Pressure-volume (PV) loop analysis remains the gold standard for studying cardiac physiology by offering a comprehensive analysis and quantitative assessment of the heart. The PV loop analysis uncovers the complex interplay between pressure and volume within the ventricle during each cardiac cycle and provide clinicians and researchers with invaluable insights into the efficiency and performance of the heart. By plotting ventricular pressure against ventricular volume, PV loops create a closed curve, signifying the dynamic changes occurring throughout the entire cardiac cycle. This review examines the importance of mastering the fundamentals of the PV loop and understanding valvular heart disease impacting the left heart.
{"title":"Understanding the Pressure-Volume Loop in Valvular Heart Disease","authors":"Mohammad Sarraf MD , Omar Chehab MD , Vinayak Nagaraja MBBS, MBiostat, FRACP","doi":"10.1016/j.hlc.2025.05.101","DOIUrl":"10.1016/j.hlc.2025.05.101","url":null,"abstract":"<div><div>Pressure-volume (PV) loop analysis remains the gold standard for studying cardiac physiology by offering a comprehensive analysis and quantitative assessment of the heart. The PV loop analysis uncovers the complex interplay between pressure and volume within the ventricle during each cardiac cycle and provide clinicians and researchers with invaluable insights into the efficiency and performance of the heart. By plotting ventricular pressure against ventricular volume, PV loops create a closed curve, signifying the dynamic changes occurring throughout the entire cardiac cycle. This review examines the importance of mastering the fundamentals of the PV loop and understanding valvular heart disease impacting the left heart.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages 31-44"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145742215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Community-based peer-support exercise programs are important for enhancing the quality of life for older people with chronic lung disease. Given the strong evidence base for these programs, it is important to have a strong understanding of the factors that facilitate participation and engagement from the perspective of participants. This study aimed to derive empirical evidence from qualitative studies on the facilitating factors supporting the participation of older people with chronic lung disease in community-based peer-support exercise programs.
Methods
Five online databases (Scopus, Medline, CINAHL, PsychInfo, and Web of Science) were searched post-2012. Data were analysed using Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Studies were assessed for quality and data extracted. Results were synthesised using qualitative metasynthesis techniques.
Results
A total of 12 studies met the inclusion criteria and were included in the review. Three themes were identified as facilitators that support the participation of older people with chronic lung disease in community exercise programs: 1. benefits of pulmonary rehabilitation, with subthemes of health benefits, psychosocial benefits, supportive safe environment, and sustained benefits; 2. barriers to pulmonary rehabilitation, with subthemes of access barriers and personal barriers; and 3. overcoming barriers and building resilience, with subthemes building knowledge and awareness and regaining independence.
Conclusions
The review highlights that physical and psychosocial benefits of pulmonary rehabilitation community-based exercise programs for older people with chronic lung disease are facilitators for participation. Peer support in understanding the experiences of others can help increase engagement. There is a need to construct approaches that address the social determinants of health in overcoming barriers to participation in community peer-support exercise programs. A limitation is a risk of losing the nuances of contextual and theoretical aspects of individual studies.
背景与目的：以社区为基础的同伴支持运动项目对提高老年慢性肺病患者的生活质量非常重要。鉴于这些项目有强有力的证据基础，从参与者的角度对促进参与和参与的因素有一个深刻的理解是很重要的。本研究旨在从定性研究中获得支持慢性肺病老年人参与社区同伴支持运动项目的促进因素的经验证据。方法：检索2012年后的Scopus、Medline、CINAHL、PsychInfo和Web of Science 5大数据库。使用系统评价和元分析指南的首选报告项目对数据进行分析。评估了研究的质量和提取的数据。结果采用定性合成技术合成。结果：共有12项研究符合纳入标准并被纳入本综述。三个主题被确定为支持患有慢性肺病的老年人参与社区锻炼计划的促进因素：1。肺康复的益处，分主题为健康益处、社会心理益处、支持性安全环境和持续益处；2. 肺部康复障碍，分主题为获取障碍和个人障碍；和3。克服障碍，建立复原力，分主题是建立知识和意识，重获独立。结论：该综述强调，肺康复社区运动项目对慢性肺病老年人的身体和心理社会益处是促进参与的因素。在理解他人经历方面的同伴支持有助于提高参与度。有必要建立解决健康的社会决定因素的方法，以克服参与社区同伴支持运动项目的障碍。限制是一种失去个体研究的背景和理论方面的细微差别的风险。
{"title":"Factors Facilitating Participation of Older Adults With Chronic Lung Disease in Community-Based, Peer-Support Exercise Programs: A Metasynthesis","authors":"Rebekkah Middleton RN, MN(Res), PhD , Christine Metusela PhD , Patricia M. Davidson RN, PhD","doi":"10.1016/j.hlc.2025.07.011","DOIUrl":"10.1016/j.hlc.2025.07.011","url":null,"abstract":"<div><h3>Background & Aim</h3><div>Community-based peer-support exercise programs are important for enhancing the quality of life for older people with chronic lung disease. Given the strong evidence base for these programs, it is important to have a strong understanding of the factors that facilitate participation and engagement from the perspective of participants. This study aimed to derive empirical evidence from qualitative studies on the facilitating factors supporting the participation of older people with chronic lung disease in community-based peer-support exercise programs.</div></div><div><h3>Methods</h3><div>Five online databases (Scopus, Medline, CINAHL, PsychInfo, and Web of Science) were searched post-2012. Data were analysed using Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Studies were assessed for quality and data extracted. Results were synthesised using qualitative metasynthesis techniques.</div></div><div><h3>Results</h3><div>A total of 12 studies met the inclusion criteria and were included in the review. Three themes were identified as facilitators that support the participation of older people with chronic lung disease in community exercise programs: 1. benefits of pulmonary rehabilitation, with subthemes of health benefits, psychosocial benefits, supportive safe environment, and sustained benefits; 2. barriers to pulmonary rehabilitation, with subthemes of access barriers and personal barriers; and 3. overcoming barriers and building resilience, with subthemes building knowledge and awareness and regaining independence.</div></div><div><h3>Conclusions</h3><div>The review highlights that physical and psychosocial benefits of pulmonary rehabilitation community-based exercise programs for older people with chronic lung disease are facilitators for participation. Peer support in understanding the experiences of others can help increase engagement. There is a need to construct approaches that address the social determinants of health in overcoming barriers to participation in community peer-support exercise programs. A limitation is a risk of losing the nuances of contextual and theoretical aspects of individual studies.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages 45-61"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145603922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.07.013
Juan Mundisugih MBBS , Ashwin Bhaskaran MBBS, MSc , Kaimin Huang MBBS , Kasun De Silva MBBS , Samual Turnbull BSc , Tai Chung So MBBS , Kenji Hashimoto MD, PhD , Anunay Gupta MD, DM , Richard G. Bennett BSc, MBChB, PhD , Yasuhito Kotake MD, PhD , Max Bickley BSc , Timothy Campbell BSc, PhD , Saurabh Kumar MBBS, PhD
Catheter ablation has emerged as a pivotal therapeutic strategy for managing scar-related ventricular tachycardia (VT) in patients with structural heart disease (SHD). However, VT ablation can be complex and challenging because of the nature of VT circuit configurations and their interplay with the underlying SHD. This review outlines our systematic approach to VT ablation within the context of SHD, focusing on preprocedural assessment, procedural techniques, and postprocedural care. By adopting a systematic approach and leveraging technological advancements, successful VT ablation outcomes can be achieved in patients with SHD.
{"title":"Stepwise Approach to Ventricular Tachycardia Ablation in Structural Heart Disease","authors":"Juan Mundisugih MBBS , Ashwin Bhaskaran MBBS, MSc , Kaimin Huang MBBS , Kasun De Silva MBBS , Samual Turnbull BSc , Tai Chung So MBBS , Kenji Hashimoto MD, PhD , Anunay Gupta MD, DM , Richard G. Bennett BSc, MBChB, PhD , Yasuhito Kotake MD, PhD , Max Bickley BSc , Timothy Campbell BSc, PhD , Saurabh Kumar MBBS, PhD","doi":"10.1016/j.hlc.2025.07.013","DOIUrl":"10.1016/j.hlc.2025.07.013","url":null,"abstract":"<div><div>Catheter ablation has emerged as a pivotal therapeutic strategy for managing scar-related ventricular tachycardia (VT) in patients with structural heart disease (SHD). However, VT ablation can be complex and challenging because of the nature of VT circuit configurations and their interplay with the underlying SHD. This review outlines our systematic approach to VT ablation within the context of SHD, focusing on preprocedural assessment, procedural techniques, and postprocedural care. By adopting a systematic approach and leveraging technological advancements, successful VT ablation outcomes can be achieved in patients with SHD.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages 62-73"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145695929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.12.010
Paloma Remior Pérez MD a,b, Robyn J. Hylind MS, CGC a, Thomas M. Roston MD, PhD a,c, Vassilios J. Bezzerides MD, PhD a,1,∗∗, Dominic J. Abrams MBBS, MD, MBA a,1,∗
{"title":"Corrigendum to: “Gene Therapy for Catecholaminergic Polymorphic Ventricular Tachycardia” [Heart Lung Circ. 32(7), (2023) 790–797.]","authors":"Paloma Remior Pérez MD a,b, Robyn J. Hylind MS, CGC a, Thomas M. Roston MD, PhD a,c, Vassilios J. Bezzerides MD, PhD a,1,∗∗, Dominic J. Abrams MBBS, MD, MBA a,1,∗","doi":"10.1016/j.hlc.2025.12.010","DOIUrl":"10.1016/j.hlc.2025.12.010","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Page e14"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.12.005
Salvatore Pepe PhD, FAHA, FESC, FCSANZ
{"title":"Innovations in Cardiovascular Care: From AI to Community Support, Celebrating 35 Years of Heart Lung and Circulation","authors":"Salvatore Pepe PhD, FAHA, FESC, FCSANZ","doi":"10.1016/j.hlc.2025.12.005","DOIUrl":"10.1016/j.hlc.2025.12.005","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages 1-4"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145904180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.hlc.2025.04.089
Andrey V. Protopopov MD , Alexander V. Bogachev-Prokophiev MD, PhD , Alexander V. Afanasyev MD, PhD , Dmitry A. Sirota MD, PhD , Sergey Ye. Khrushchev PhD , Pavel S. Ruzankin PhD , Maxim O. Zhulkov MD, PhD , Aleksandr M. Chernyavskiy MD, PhD
Aim
The optimal surgical strategy for patients with post-infarction left ventricular aneurysms remains unclear. The superiority of the Dor technique over the Cooley repair has not been demonstrated in terms of long-term outcomes. This study aimed to compare the clinical outcomes between the Dor and Cooley repair techniques.
Methods
Patients who underwent left ventricular repair between 2003 and 2021 were retrospectively recruited. All the patients underwent left ventricular aneurysm repair and coronary artery bypass grafting. For comparative assessment of outcomes between the Cooley and Dor groups, 1:2 propensity score matching was applied. The primary study endpoint was long-term mortality, whereas the secondary endpoints included major adverse cardiac and cerebrovascular events (MACCEs), defined as a combination of cardiac death, myocardial infarction, stroke, readmission due to nonfatal myocardial infarction, and repeat revascularisation.
Results
The median follow-up period was 106 months (interquartile range: 41–148). Eight hospital deaths (2.1%) occurred in the Cooley group and 11 (5.1%) in the Dor group within 30 days postoperatively. For the entire follow-up period, the Dor group had lower mortality (hazard ratio [HR] 0.67; 95% confidence interval [CI] 0.45–0.99; p=0.043) and greater freedom from myocardial infarction (HR 0.41; 95% CI 0.18–0.93; p=0.033). The overall incidence of MACCEs was significantly lower in the Dor group (HR 0.65; 95% Cl 0.48–0.88; p=0.005). The Dor group showed a notably lower readmission rate (HR 0.63; 95% Cl 0.42–0.94; p=0.022).
Conclusions
For long-term survival and MACCEs, the Dor procedure demonstrated better outcomes than the Cooley reconstruction.
{"title":"Long-Term Outcomes of Dor Versus Cooley Procedure in Patients With Post-Infarction Left Ventricular Aneurysm Repair: A Propensity Score-Matched Study","authors":"Andrey V. Protopopov MD , Alexander V. Bogachev-Prokophiev MD, PhD , Alexander V. Afanasyev MD, PhD , Dmitry A. Sirota MD, PhD , Sergey Ye. Khrushchev PhD , Pavel S. Ruzankin PhD , Maxim O. Zhulkov MD, PhD , Aleksandr M. Chernyavskiy MD, PhD","doi":"10.1016/j.hlc.2025.04.089","DOIUrl":"10.1016/j.hlc.2025.04.089","url":null,"abstract":"<div><h3>Aim</h3><div>The optimal surgical strategy for patients with post-infarction left ventricular aneurysms remains unclear. The superiority of the Dor technique over the Cooley repair has not been demonstrated in terms of long-term outcomes. This study aimed to compare the clinical outcomes between the Dor and Cooley repair techniques.</div></div><div><h3>Methods</h3><div>Patients who underwent left ventricular repair between 2003 and 2021 were retrospectively recruited. All the patients underwent left ventricular aneurysm repair and coronary artery bypass grafting. For comparative assessment of outcomes between the Cooley and Dor groups, 1:2 propensity score matching was applied. The primary study endpoint was long-term mortality, whereas the secondary endpoints included major adverse cardiac and cerebrovascular events (MACCEs), defined as a combination of cardiac death, myocardial infarction, stroke, readmission due to nonfatal myocardial infarction, and repeat revascularisation.</div></div><div><h3>Results</h3><div>The median follow-up period was 106 months (interquartile range: 41–148). Eight hospital deaths (2.1%) occurred in the Cooley group and 11 (5.1%) in the Dor group within 30 days postoperatively. For the entire follow-up period, the Dor group had lower mortality (hazard ratio [HR] 0.67; 95% confidence interval [CI] 0.45–0.99; p=0.043) and greater freedom from myocardial infarction (HR 0.41; 95% CI 0.18–0.93; p=0.033). The overall incidence of MACCEs was significantly lower in the Dor group (HR 0.65; 95% Cl 0.48–0.88; p=0.005). The Dor group showed a notably lower readmission rate (HR 0.63; 95% Cl 0.42–0.94; p=0.022).</div></div><div><h3>Conclusions</h3><div>For long-term survival and MACCEs, the Dor procedure demonstrated better outcomes than the Cooley reconstruction.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"35 1","pages":"Pages 127-136"},"PeriodicalIF":2.2,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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