Heart, Lung and Circulation最新文献

{"title":"Diabetes is an Increasingly Common Issue After Heart Transplantation: A Case for Integrated Diabetes Care","authors":"Lisa M. Raven MBBS ,&nbsp;Andrew Jabbour PhD ,&nbsp;Peter S. Macdonald PhD ,&nbsp;Jerry R. Greenfield PhD ,&nbsp;Christopher A. Muir PhD","doi":"10.1016/j.hlc.2025.04.081","DOIUrl":"10.1016/j.hlc.2025.04.081","url":null,"abstract":"<div><h3>Background</h3><div>Orthotopic heart transplantation (OHT) survival rates have improved with advances in immunosuppression over the last 20 years. With these improvements, there has been a greater focus on post-transplant care. Diabetes is common after transplantation and may be pre-existing (type 2 diabetes mellitus [T2DM]) or develop after transplant (post-transplant diabetes mellitus [PTDM]). The aim of this study was to compare the incidence and prevalence of diabetes in OHT recipients in two cohorts separated by 20 years.</div></div><div><h3>Methods</h3><div>Retrospective audit comparing the prevalence of T2DM and cumulative 2-year incidence of PTDM in 88 consecutive OHT recipients in 1996–1998 and 141 consecutive OHT recipients in 2015–2018 at the same tertiary referral teaching hospital.</div></div><div><h3>Results</h3><div>The prevalence of pre-transplant T2DM at the time of OHT increased three-fold between 1998 and 2018, from 6% (n=5) to 18% (n=25) respectively (p=0.009). Similarly, the incidence of PTDM increased from 16% (n=13) in 1998 to 36% (n=42) in 2018 (p=0.001). OHT recipients who developed PTDM were older in 2018 vs 1998 (mean age 52 [±11] vs 44 [±9] years; p=0.03). The mean age was not different between individuals with T2DM between the 1998 and 2018 eras. Body mass index was not different between the 1998 and 2018 eras in any of the diabetes status subgroups.</div></div><div><h3>Conclusions</h3><div>The incidence and prevalence of diabetes after OHT at our Australian institution has increased over 20 years. With improved OHT survival and rates of diabetes, endocrinologists should be incorporated into the care teams of heart transplant recipients. Further studies of glucose-lowering therapies in patients with diabetes after transplantation are warranted.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1290-1294"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Utility of Infrared Thermography and Hyperspectral Imaging in Peripheral Artery Disease: A Systematic Review","authors":"Olavi Yli-Harja BM ,&nbsp;Tomppa Pakarinen DSc ,&nbsp;Emmi Peltola MSc ,&nbsp;Meri Hämäläinen MSc ,&nbsp;Antti Vehkaoja DSc ,&nbsp;Niku Oksala MD, PhD, DSc","doi":"10.1016/j.hlc.2025.03.017","DOIUrl":"10.1016/j.hlc.2025.03.017","url":null,"abstract":"<div><h3>Background</h3><div>Peripheral artery disease (PAD) is a prevalent vascular disorder that reduces blood flow and tissue oxygenation. Early detection is crucial to optimise treatment outcomes and minimise ulceration or gangrene and possible subsequent amputations. This systematic review evaluated the diagnostic significance and clinical utility of infrared thermography (IRT) and hyperspectral imaging (HSI) as non-invasive, contactless techniques for PAD and chronic limb-threatening ischaemia assessment. Infrared thermography assesses blood perfusion by detecting temperature changes in limbs and HSI can be utilised to evaluate oxygen saturation, and deoxyhaemoglobin and oxyhaemoglobin concentrations in superficial tissue.</div></div><div><h3>Methods</h3><div>After a comprehensive PubMed literature search, a total of 15 articles were included in the final analysis: eight studies utilising IRT for circulation assessment, six studies employing HSI, and one study combining the two. A total 607 participants with PAD were included.</div></div><div><h3>Results</h3><div>In the IRT studies, varying levels of correlations were found between established assessment modalities and temperature changes. Significant, but mostly modest, correlations were discovered in the HSI studies—particularly with deoxyhaemoglobin, oxyhaemoglobin, and the ankle–brachial index—making the clinical significance of the results unclear, but still suggesting that HSI has potential for assessing and screening PAD. Head-to-head, HSI accurately detected immediate perfusion changes after PAD treatment, while IRT did not, suggesting that HSI-derived parameters may be more precise for perfusion assessment.</div></div><div><h3>Conclusions</h3><div>The results indicate that both IRT and HSI hold promise for assessing circulation, oxygenation, and perfusion in participants with vascular deficiency. Further research with larger sample sizes and standardised measurement protocols is needed to validate the clinical utility of IRT and HSI.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1194-1208"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144855097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validating Biventricular Pressure–Volume Loop–Derived Cardiac Output Against Thermodilution: A Step Towards Precision Haemodynamic Assessment","authors":"Mohammad Sarraf MD ,&nbsp;Vinayak Nagaraja MBBS, MBiostat, FRACP","doi":"10.1016/j.hlc.2025.10.004","DOIUrl":"10.1016/j.hlc.2025.10.004","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1147-1149"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145478818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral Versus Bilateral Antegrade Cerebral Perfusion in Aortic Arch Surgery: Systematic Review and Meta-Analysis of Randomised Controlled Trials and Propensity-Matched Studies","authors":"Kristine Santos BSc ,&nbsp;Emmanuel Mark Velasco MD ,&nbsp;Mohammad Mawasi ,&nbsp;Tomasz Płonek MD, PhD, FEBCTS(cardiac)","doi":"10.1016/j.hlc.2025.03.018","DOIUrl":"10.1016/j.hlc.2025.03.018","url":null,"abstract":"<div><h3>Background</h3><div>Selective antegrade cerebral perfusion<span><span>, via unilateral antegrade cerebral perfusion (uACP) or bilateral antegrade cerebral perfusion (bACP) approaches, is used in aortic arch surgery to protect the brain during circulatory arrest. Previous meta-analyses, based on unmatched observational data, found no differences between these techniques. Our updated meta-analysis exclusively examines high-quality evidence from </span>randomised controlled trials and propensity-matched studies.</span></div></div><div><h3>Method</h3><div>A literature search of MEDLINE, Scopus, and Cochrane databases identified relevant studies up to November 2024. Pooled odds ratios (ORs) and mean differences with 95% confidence intervals (CIs) were calculated using RevMan version 8.13.0.</div></div><div><h3>Results</h3><div><span>We included eight studies comprising 2,072 patients, with 1,025 (49.5%) patients in the uACP group. The pooled analysis revealed that uACP was associated with a shorter hospital length of stay (mean differences −2.2 days; 95% CI −3.6 to −0.7; p&lt;0.05) and a reduced incidence of permanent neurological dysfunction (OR 0.7; 95% CI 0.5 to 0.9; p&lt;0.05). However, uACP was linked to a higher incidence of acute kidney injury (OR 1.5; 95% CI 1.1 to 2.0; p&lt;0.05). No statistically significant differences were observed between uACP and bACP in terms of aortic cross-clamp time, </span>cardiopulmonary bypass<span> duration, ventilation time, transient neurological deficits, intensive care unit<span> length of stay, 30-day mortality, and re-exploration for bleeding.</span></span></div></div><div><h3>Conclusions</h3><div>Our meta-analysis confirmed several comparable outcomes between uACP and bACP as reported in previous reviews. However, our study identified additional findings, such as a reduced hospital length of stay and lower incidence of permanent neurological dysfunction associated with uACP, alongside a higher risk of acute kidney injury.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1218-1227"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Cardiac Output Measurement Techniques: Thermodilution Versus Biventricular Pressure-Volume Loop Recordings in Pigs","authors":"Simone Juel Dragsbaek MD ,&nbsp;Mathilde Emilie Kirk MD ,&nbsp;Cecilie Dahl Baltsen BMSc ,&nbsp;Asger Andersen MD, PhD ,&nbsp;Mads Dam Lyhne MD, PhD","doi":"10.1016/j.hlc.2025.05.080","DOIUrl":"10.1016/j.hlc.2025.05.080","url":null,"abstract":"<div><h3>Background</h3><div>Cardiac output (CO) measurement is crucial in cardiovascular research. Pressure-volume (PV) loop recordings provide detailed information on cardiac function, including CO. This study aimed to compare CO measurements obtained from biventricular PV loop recordings with thermodilution (TD) as a reference method in pigs.</div></div><div><h3>Method</h3><div>The TD-CO was measured by right heart catheterisation. The PV-derived CO was obtained from both ventricles simultaneously, both during ongoing ventilation and in transient apnoea. Data were compared using the Bland-Altman method. The percentage error (PE%) and linear regression were calculated between the TD-CO and PV-derived CO.</div></div><div><h3>Results</h3><div>Simultaneous CO measurements from 43 pigs were analysed. Compared to thermodilution, the lowest bias was found in PV-derived CO from the left ventricle during ongoing ventilation (0.02 L/min, 95% confidence interval [0.2–0.3]) with a PE% of 30% during ongoing ventilation. The highest bias was found in PV-derived CO from the right ventricle during ongoing ventilation (0.9 L/min, 95% CI [0.5–1.3]) with a PE% of 67% during ongoing ventilation.</div></div><div><h3>Conclusions</h3><div>PV-derived CO from the left ventricle showed very good agreement with TD-CO, with minimal bias, while PV-CO measurements from the right ventricle showed higher inaccuracy, likely due to anatomical differences between the ventricles.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1295-1300"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144882790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyrotropin Modulates Calcium Handling and Contractility in Adult Cardiac Myocytes","authors":"Marisa Sepúlveda PhD ,&nbsp;Florencia Racioppi PhD ,&nbsp;Juan Ignacio Burgos PhD ,&nbsp;Alexandra Murillo MD ,&nbsp;Julieta Fernandez-Ruocco PhD ,&nbsp;Luis Gonano PhD ,&nbsp;Gabriel Neiman PhD ,&nbsp;Santiago Miriuka PhD ,&nbsp;Andrea Fellet PhD ,&nbsp;Oscar Casis PhD ,&nbsp;Emiliano Medei PhD ,&nbsp;German Colareda PhD ,&nbsp;Martín Vila Petroff PhD","doi":"10.1016/j.hlc.2025.07.009","DOIUrl":"10.1016/j.hlc.2025.07.009","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages e153-e156"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145307937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Timing, Diagnosis, and Potential Preventability of 30-Day Unplanned Readmissions After a Heart Failure Hospitalisation: Implications for Care Quality","authors":"James Fryar MD ,&nbsp;Sunnya Khawaja MPH ,&nbsp;Trang Dang MA, MHlthEcPol ,&nbsp;Wandy Chan MBChB, PhD ,&nbsp;Maryam Khorramshahi Bayat MD ,&nbsp;William Parsonage BM, BS, DM ,&nbsp;Isuru Ranasinghe MBChB, MMed(Clin Epi), PhD","doi":"10.1016/j.hlc.2025.04.085","DOIUrl":"10.1016/j.hlc.2025.04.085","url":null,"abstract":"<div><h3>Aim</h3><div>To assess timing, causes, and potential preventability of unplanned readmissions within 30 days of heart failure hospitalisation and how they vary by age and sex across the population.</div></div><div><h3>Method</h3><div>We conducted a cohort study using hospitalisation data from 2013 to 2017 from all public and most private hospitals in Australia and New Zealand, including 197,648 patients aged ≥18 years (mean age 78.2 [standard deviation 12.3] years, 52.4% male, 13.3% &lt;65 years) with a primary diagnosis of heart failure. The main outcomes included the timing of 30-day unplanned readmissions, the diagnoses associated with these, and their potential preventability. Preventability was determined by categorising readmission diagnoses into the following: 1) potential hospital-acquired complication, 2) recurrent heart failure, 3) clinically related to heart failure, and 4) all other diagnoses. Groups 1 and 2 were deemed most preventable.</div></div><div><h3>Results</h3><div>A total of 43,011 (21.8%) patients had one or more unplanned readmissions within 30 days. The peak readmission risk occurred on days 2–4 post-discharge with 25,318 (58.9%) occurring within 2 weeks. When grouped, diagnoses consistent with a potential hospital-acquired complication (group 1) accounted for 41.7% (most commonly pneumonia, atrial fibrillation/flutter, and myocardial infarction), readmission for recurrent heart failure (group 2) comprised 38.2%, and groups 3 and 4 consisted of 11.5% and 8.6%, respectively. Although heart failure hospitalisation occurred more frequently in older adults, the risk of readmission exceeded 20% in all age groups, and the timing and potential preventability were not clinically significantly different across age and sex.</div></div><div><h3>Conclusions</h3><div>The peak risk of unplanned readmission occurred in the first few days after discharge, often for potentially preventable reasons such as hospital-acquired complications and recurrent heart failure. Such early and potentially preventable readmissions suggest many may be related to suboptimal quality of hospital care and discharge practices. Future clinical and policy interventions should target improving hospital-based heart failure care quality to reduce avoidable readmissions.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1281-1289"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographical and Temporal Variation in Coronary Intravascular Imaging Utilisation and Barriers to Wider Adoption: A Systematic Review and Pooled Analysis","authors":"Samuel Norman MChD ,&nbsp;Anoop N. Koshy MBBS, PhD ,&nbsp;Anna Wan MBBS ,&nbsp;Sinjini Biswas MBBS, PhD ,&nbsp;William Wilson MBBS ,&nbsp;David Eccleston MBBS, MMedSci ,&nbsp;Jeffrey Lefkovits MBBS","doi":"10.1016/j.hlc.2025.04.086","DOIUrl":"10.1016/j.hlc.2025.04.086","url":null,"abstract":"<div><h3>Background</h3><div>Despite the accumulation of randomised data demonstrating improved outcomes with intravascular imaging (IVI)-guided percutaneous coronary intervention (PCI), utilisation is uncommon in most countries. This systematic review maps geographical and temporal trends in IVI use using PCI registry and government data.</div></div><div><h3>Method</h3><div>A systematic review adhering to the PRISMA framework was conducted to identify provincial, national, and international data sets reporting real-world IVI rates published between 2014 and 2024.</div></div><div><h3>Results</h3><div>A total of 36 publications from 24 countries were included, totalling 9,459,897 patients. Intravascular ultrasound was the preferred imaging modality, with optical coherence tomography accounting for &lt;10% of IVI. Most countries reported low rates of IVI uptake, however, significant increases over time were observed. Rates varied significantly between and within regions and countries. Asia had the highest mean utilisation rate (35.4%; standard deviation, 35.9), followed by the Americas (9.3%; 5.7), Europe (5.7%; 4.9), and Oceania (4.5%; 2.6).</div></div><div><h3>Conclusions</h3><div>Significant variability in IVI utilisation was observed across regions and countries. Most countries reported low IVI rates; however, adoption increased over time in most areas. Local variables such as health care system characteristics, physician preferences, and financial considerations appear to inform IVI rates more than clinical factors.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1179-1193"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 10-Year Review of Intravascular Imaging Use in Australia: Findings From a Statewide Registry","authors":"Arun Sharma MD, B.Biomed ,&nbsp;Riley J. Batchelor MMed, FRACP ,&nbsp;Diem Dinh PhD, BAppSc ,&nbsp;Angela Brennan CCRN ,&nbsp;Sinjini Biswas PhD, FRACP ,&nbsp;Simon Thackray MBBS ,&nbsp;Jacob Park MD ,&nbsp;Samuel Norman MChd, FRACP ,&nbsp;William Wilson FRACP ,&nbsp;Ronen Gurvitch FRACP ,&nbsp;Dion Stub PhD, FRACP ,&nbsp;Jeffrey Lefkovits FRACP, FCSANZ ,&nbsp;Anoop N. Koshy PhD, FRACP","doi":"10.1016/j.hlc.2025.08.017","DOIUrl":"10.1016/j.hlc.2025.08.017","url":null,"abstract":"<div><h3>Background</h3><div>In several recent randomised trials, intravascular imaging (IVI)-guided percutaneous intervention (PCI) has demonstrated superiority to angiography-guided PCI, particularly, in certain lesion subsets. Given the recent Medicare Benefits Schedule (MBS) criteria changes to incorporate intravascular ultrasound (IVUS) for PCI, we sought to report the real-world use of IVI.</div></div><div><h3>Methods</h3><div>Consecutive patients undergoing PCI entered into the Victorian Cardiac Outcomes Registry from 2013 to 2022 were included. Patients presenting with cardiogenic shock or out-of-hospital cardiac arrest requiring intubation were excluded given their distinct clinical urgency and unstable physiology. The overall use of either IVUS and optical coherence tomography (OCT) was assessed. Additionally, we assessed the use of IVI in PCI in scenarios as per MBS criteria: lesion length ≥28 mm (using stent length as a surrogate marker) and left main PCI, as well as in cases of in-stent restenosis.</div></div><div><h3>Results</h3><div>A total of 104,722 PCI procedures were included. IVUS/OCT was used in 3,137 (3.0%) cases. There was a significant increase in rates of IVI-PCI over the study period, increasing from 2.2% (n=105 of 4,809) in 2013 to 6.3% (n=730 of 11,651) in 2022 (p=0.005). Comparing 2013–2017 with 2018–2022, there was a significant increase in IVUS/OCT use for left main disease (p=0.01) and PCIs with stent length ≥28 mm (p=0.001). Of the 39,492 PCI cases with stent length ≥28 mm, IVUS/OCT was used in 3.3% of cases (1,313), with these patients being younger (p=0.001) and more likely to have diabetes (p=0.001) and previous PCI (p=0.001). Of the 1,831 left main PCI cases, IVI was used in 460 (25.1%).</div></div><div><h3>Conclusions</h3><div>Although IVI use has grown significantly, 75% of left main coronary artery PCIs have still been done without imaging. With recent MBS changes, we anticipate further growth for IVI-guided PCI.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages 1235-1240"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Braess's Network Paradox in Coronary and Vascular Revascularisation: Adding Game Theory to Virchow’s Triad","authors":"Hutan Ashrafian MBBS, PhD, MBA","doi":"10.1016/j.hlc.2025.04.094","DOIUrl":"10.1016/j.hlc.2025.04.094","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"34 11","pages":"Pages e164-e166"},"PeriodicalIF":2.2,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145478820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}