S. Alkan, Emine Kübra Dindar Demiray, Nurullah Tarhan, T. Önder
Brucellosis is a zoonotic disease, seen globally, especially in developing countries and it can affect many organs. Urinary involvement of this disease is a very rare. Pyelonephritis, interstitial nephritis, glomerulonephritis, nephropathy are the reported urinary involvements. In this study, we aimed to report a case of Brucella pyelonephritis, who had complaints mimicking acute bacterial pyelonephritis, with a history of polycystic kidney disease and calculi in the left kidney.
{"title":"A case of Brucella pyelonephritis: a rare case","authors":"S. Alkan, Emine Kübra Dindar Demiray, Nurullah Tarhan, T. Önder","doi":"10.53986/ibjm.2022.0012","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0012","url":null,"abstract":"Brucellosis is a zoonotic disease, seen globally, especially in developing countries and it can affect many organs. Urinary involvement of this disease is a very rare. Pyelonephritis, interstitial nephritis, glomerulonephritis, nephropathy are the reported urinary involvements. In this study, we aimed to report a case of Brucella pyelonephritis, who had complaints mimicking acute bacterial pyelonephritis, with a history of polycystic kidney disease and calculi in the left kidney.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"66 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79779752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Epicardial fat tissue (EFT) is a significant risk factor for cardiovascular diseases. This study aimed to investigate whether there is a relationship between the fibrosis-4 index (FIB-4 index) and EFT in newly-diagnosed hypertensive patients and explore the usability of the FIB-4 index in predicting non-dipper blood pressure (BP) pattern. Materials and methods: Our case–control study consisted of 210 patients in 3 groups according to BP values, namely normotensive, dipper, and non-dipper groups. Transthoracic echocardiography and 24-h ambulatory BP monitoring were performed in all patients. Results: The median FIB-4 index was higher in the non-dipper group [1.56 (1.10-2)] than in the dipper [1 (0.71-1.32)] and normotensive groups [0.96 (0.69-1.32)] (p < 0.001, for both). A positive correlation was observed between EFT and the FIB-4 index (r=0.389, p<0.001). In multivariate logistic regression analysis, EFT (odds ratio (OR): 0.506, 95% confidence interval (CI): 1.288-2.135; p<0.001) and FIB-4 index (OR: 1.099, 95% CI: 1.621–5.556; p<0.001) were found to be independent predictors of non-dipper BP. In the receiver operating characteristic curve analysis, the FIB-4 index had 68% sensitivity and 72% specificity at a value >1.25 (area under the curve: 0.751, 95%CI: 0.679-0.823, p<0.001). Conclusions: In newly-diagnosed hypertensive people, the FIB-4 index is related to non-dipper BP patterns. FIB-4 index appears to be a helpful tool in assessing risk associated with cardiovascular disease.
心外膜脂肪组织(EFT)是心血管疾病的重要危险因素。本研究旨在探讨新诊断高血压患者的纤维化-4指数(FIB-4指数)与EFT之间是否存在相关性，并探讨FIB-4指数在预测非杓型血压(BP)模式中的可用性。材料与方法:我们的病例对照研究包括210例患者，根据血压值分为3组，即正常血压组、北斗组和非北斗组。所有患者均行经胸超声心动图和24小时动态血压监测。结果:非侧翻组FIB-4指数中位数[1.56(1.10-2)]高于侧翻组[1(0.71-1.32)]和正常血压组[0.96 (0.69-1.32)](p均< 0.001)。EFT与FIB-4指数呈正相关(r=0.389, p = 1.25，曲线下面积0.751,95%CI: 0.679 ~ 0.823, p<0.001)。结论:在新诊断的高血压患者中，FIB-4指数与非降血压模式有关。FIB-4指数似乎是评估心血管疾病相关风险的有用工具。
{"title":"Fibrosis-4 index: A new marker to predict non-dipper blood pressure pattern in patients with newly diagnosed hypertension","authors":"U. Küçük, K. Arslan","doi":"10.53986/ibjm.2022.0011","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0011","url":null,"abstract":"Introduction: Epicardial fat tissue (EFT) is a significant risk factor for cardiovascular diseases. This study aimed to investigate whether there is a relationship between the fibrosis-4 index (FIB-4 index) and EFT in newly-diagnosed hypertensive patients and explore the usability of the FIB-4 index in predicting non-dipper blood pressure (BP) pattern. Materials and methods: Our case–control study consisted of 210 patients in 3 groups according to BP values, namely normotensive, dipper, and non-dipper groups. Transthoracic echocardiography and 24-h ambulatory BP monitoring were performed in all patients. Results: The median FIB-4 index was higher in the non-dipper group [1.56 (1.10-2)] than in the dipper [1 (0.71-1.32)] and normotensive groups [0.96 (0.69-1.32)] (p < 0.001, for both). A positive correlation was observed between EFT and the FIB-4 index (r=0.389, p<0.001). In multivariate logistic regression analysis, EFT (odds ratio (OR): 0.506, 95% confidence interval (CI): 1.288-2.135; p<0.001) and FIB-4 index (OR: 1.099, 95% CI: 1.621–5.556; p<0.001) were found to be independent predictors of non-dipper BP. In the receiver operating characteristic curve analysis, the FIB-4 index had 68% sensitivity and 72% specificity at a value >1.25 (area under the curve: 0.751, 95%CI: 0.679-0.823, p<0.001). Conclusions: In newly-diagnosed hypertensive people, the FIB-4 index is related to non-dipper BP patterns. FIB-4 index appears to be a helpful tool in assessing risk associated with cardiovascular disease.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"216 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74936868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kukov, M. Peruhova, Atanas Syarov, I. Altankova, N. Yurukova, A. Goncharov, R. Vazharova, Anoaneta Mihova, T. Velikova, Y. Uzunova
Introduction: Recent studies have shown that the intestinal microbiota can modulate certain systemic metabolic and immune responses, including liver graft function and the development of complications in patients after liver transplantation (LT). Akkermansia muciniphila (AKM) and Faecalibacterium prausnitzii (FAEP) are two of the most abundant gut commensal bacteria, with mucosa-protective and anti-inflammatory effects that are important for maintaining normal intestinal homeostasis and gut barrier function. Our objective was to quantify levels of Akkermansia muciniphila and Faecalibacterium prausnitzii in immunosuppressed patients with LT. Materials and methods: Fecal samples from 23 liver transplant patients (15 adults and 8 children) and 9 non-LT controls were examined. Bacterial DNA was isolated from the samples using the stool DNA isolation kit and the obtained DNA was analyzed with commercially available qPCR kit for AKM and FAEP. Results: We found a statistically significant decrease in the amount of AKM and FAEP compared to the control group. The median values were: for AKM 8.75 for patients and 10.25 for the control group (p = 0.030), and for FAEP 9.72 and 10.47, p = 0.003, respectively. In children after LT, this difference was also statistically significant: AKM (p = 0.051) and FAEP (p = 0.014). In contrast no statistically significant differences were found between adult patients and controls, AKM (p = 0.283) and FAEP (p = 0.056), although the amount of both bacteria showed tendency for reduction. Conclusions: In this pilot study, we found a reduction in the total amount of the two studied bacteria in transplanted patients compared to the control healthy group.
{"title":"Alterations of gut bacteria Akkermansia muciniphila and Faecalibacterium prausnitzii in late post-transplant period after liver transplantation","authors":"A. Kukov, M. Peruhova, Atanas Syarov, I. Altankova, N. Yurukova, A. Goncharov, R. Vazharova, Anoaneta Mihova, T. Velikova, Y. Uzunova","doi":"10.53986/ibjm.2022.0010","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0010","url":null,"abstract":"Introduction: Recent studies have shown that the intestinal microbiota can modulate certain systemic metabolic and immune responses, including liver graft function and the development of complications in patients after liver transplantation (LT). Akkermansia muciniphila (AKM) and Faecalibacterium prausnitzii (FAEP) are two of the most abundant gut commensal bacteria, with mucosa-protective and anti-inflammatory effects that are important for maintaining normal intestinal homeostasis and gut barrier function. Our objective was to quantify levels of Akkermansia muciniphila and Faecalibacterium prausnitzii in immunosuppressed patients with LT. Materials and methods: Fecal samples from 23 liver transplant patients (15 adults and 8 children) and 9 non-LT controls were examined. Bacterial DNA was isolated from the samples using the stool DNA isolation kit and the obtained DNA was analyzed with commercially available qPCR kit for AKM and FAEP. Results: We found a statistically significant decrease in the amount of AKM and FAEP compared to the control group. The median values were: for AKM 8.75 for patients and 10.25 for the control group (p = 0.030), and for FAEP 9.72 and 10.47, p = 0.003, respectively. In children after LT, this difference was also statistically significant: AKM (p = 0.051) and FAEP (p = 0.014). In contrast no statistically significant differences were found between adult patients and controls, AKM (p = 0.283) and FAEP (p = 0.056), although the amount of both bacteria showed tendency for reduction. Conclusions: In this pilot study, we found a reduction in the total amount of the two studied bacteria in transplanted patients compared to the control healthy group.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79115491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Yıldız, Murat Emre Tokur, Bugra Özlem, Özlem Arık, Canan Balcı
Introduction: Treatment approach in COVID-19 infection consists of antiviral, immunomodulatory, and supportive treatments. Convalescent plasma, immune plasma or hyperimmune plasma refers to the plasma that consisting of high titer polyclonal antibodies against the virus and are amidst the immunomodulatory treatments. Although it has been reported that immune plasma treatment of COVID-19 reduces hospital stay and mortality, the efficacy of immune plasma with COVID-19 infection is not clear yet. The present study aims to investigate the efficacy of immune plasma in patients who are followed up in the intensive care unit with the diagnosis of COVID-19. Materials and methods: In this retrospective study, the patients who were hospitalized in the intensive care unit with the diagnosis of COVID-19 infection were divided into two groups: those who received IP treatment (Group 1; n=28) and those who did not (Group 2; n=25). The biochemical C -reactive protein, lactate-dehydrogenase, ferritin, D-dimer, total bilirubin, creatine levels, hematological parameters (Leukocyte, neutrophil, lymphocyte, platelet counts), clinical sepsis scores (SOFA, APACHE scores) and mortality rates of the patients were evaluated according to groups. Results: There was no statistically significant difference between Group 1 and Group 2 in terms of the presence of mechanical ventilation support and tracheostomy, comorbidities, laboratory values, C -reactive protein, SOFA, APACHE scores. The mortality rate was 61% in Group 1 and 52% in Group 2. Conclusions: Our findings revealed that immune plasma treatment was not effective in recovery and decreasing the mortality rates in the COVID-19 infected intensive care unit patients. Further studies are needed to investigate the efficacy of administering immunomodulatory therapies on the outcome before the hyper inflammatory process starts.
{"title":"Evaluation of the efficacy of immune plasma treatment in COVID-19 infected intensive care unit patients","authors":"E. Yıldız, Murat Emre Tokur, Bugra Özlem, Özlem Arık, Canan Balcı","doi":"10.53986/ibjm.2022.0009","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0009","url":null,"abstract":"Introduction: Treatment approach in COVID-19 infection consists of antiviral, immunomodulatory, and supportive treatments. Convalescent plasma, immune plasma or hyperimmune plasma refers to the plasma that consisting of high titer polyclonal antibodies against the virus and are amidst the immunomodulatory treatments. Although it has been reported that immune plasma treatment of COVID-19 reduces hospital stay and mortality, the efficacy of immune plasma with COVID-19 infection is not clear yet. The present study aims to investigate the efficacy of immune plasma in patients who are followed up in the intensive care unit with the diagnosis of COVID-19. Materials and methods: In this retrospective study, the patients who were hospitalized in the intensive care unit with the diagnosis of COVID-19 infection were divided into two groups: those who received IP treatment (Group 1; n=28) and those who did not (Group 2; n=25). The biochemical C -reactive protein, lactate-dehydrogenase, ferritin, D-dimer, total bilirubin, creatine levels, hematological parameters (Leukocyte, neutrophil, lymphocyte, platelet counts), clinical sepsis scores (SOFA, APACHE scores) and mortality rates of the patients were evaluated according to groups. Results: There was no statistically significant difference between Group 1 and Group 2 in terms of the presence of mechanical ventilation support and tracheostomy, comorbidities, laboratory values, C -reactive protein, SOFA, APACHE scores. The mortality rate was 61% in Group 1 and 52% in Group 2. Conclusions: Our findings revealed that immune plasma treatment was not effective in recovery and decreasing the mortality rates in the COVID-19 infected intensive care unit patients. Further studies are needed to investigate the efficacy of administering immunomodulatory therapies on the outcome before the hyper inflammatory process starts.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84255795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antibiotic resistance is a significant issue for the medical community, worldwide. Many bacteria develop drug resistance by utilizing multidrug resistant or MDR efflux pumps that can export antibiotics from bacterial cells. Antibiotics are expelled from bacteria by efflux pumps a part of the resistance nodulation division (RND) family. Types of RND efflux pumps include the AcrAB-TolC tripartite protein pump. There are an excessive number of antibiotic compounds that have been discovered; however, only a few antibiotics are effective against MDR bacteria. Many bacteria become drug resistant when sharing genes that encode MDR efflux pump expression. MDR efflux pump encoding genes are incorporated into plasmids and then shared among bacteria. As a consequence, advancements in genetic engineering can sufficiently target and edit pathogenic bacterial genomes for perturbing drug resistance mechanisms. In this perspective and review, support will be provided for utilizing genetic modifications as an antimicrobial approach and tool that may effectively combat bacterial MDR. Ayhan et al. found that deleting acrB, acrA, and tolC increased the levels of antibiotic sensitivity in Escherichia coli. Researchers also found that glucose, glutamate, and fructose all induced the absorption of antibiotics by upregulating the gene expression of maeA and maeB that is a part of the MAL-pyruvate pathway. Therefore, the current perspective and review will discuss the potential efficacy of reducing antibiotic resistance by inhibiting genes that encode efflux protein pump expression while simultaneously upregulating metabolic genes for increased antibiotic uptake.
{"title":"Reducing bacterial antibiotic resistance by targeting bacterial metabolic pathways and disrupting RND efflux pump activity","authors":"Tatiana Hillman","doi":"10.53986/ibjm.2022.0008","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0008","url":null,"abstract":"Antibiotic resistance is a significant issue for the medical community, worldwide. Many bacteria develop drug resistance by utilizing multidrug resistant or MDR efflux pumps that can export antibiotics from bacterial cells. Antibiotics are expelled from bacteria by efflux pumps a part of the resistance nodulation division (RND) family. Types of RND efflux pumps include the AcrAB-TolC tripartite protein pump. There are an excessive number of antibiotic compounds that have been discovered; however, only a few antibiotics are effective against MDR bacteria. Many bacteria become drug resistant when sharing genes that encode MDR efflux pump expression. MDR efflux pump encoding genes are incorporated into plasmids and then shared among bacteria. As a consequence, advancements in genetic engineering can sufficiently target and edit pathogenic bacterial genomes for perturbing drug resistance mechanisms. In this perspective and review, support will be provided for utilizing genetic modifications as an antimicrobial approach and tool that may effectively combat bacterial MDR. Ayhan et al. found that deleting acrB, acrA, and tolC increased the levels of antibiotic sensitivity in Escherichia coli. Researchers also found that glucose, glutamate, and fructose all induced the absorption of antibiotics by upregulating the gene expression of maeA and maeB that is a part of the MAL-pyruvate pathway. Therefore, the current perspective and review will discuss the potential efficacy of reducing antibiotic resistance by inhibiting genes that encode efflux protein pump expression while simultaneously upregulating metabolic genes for increased antibiotic uptake.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"183 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86813367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: During COVID-19 pandemic, when social distancing becomes compulsory for all, a nation-wide school closure was implemented. The aim of this paper is to assess the impact of COVID-19 lockdown on children with ASD and their families in Tripoli, Libya. Materials and Methods: We conducted face-to-face interviews with parents of children with Autism Spectrum Disorder (ASD) during the period of the outbreak between June to December 2020. The Modified Check list of Autism in Toddlers (M-CHAT) was used to evaluate patients. Results: 250 children diagnosed of ASD were included. The prevalence of aggressive behaviour had increased by 47% that of loss of communication is 33%, that of poor interaction is 52% and that of anxiety among families is 27%, although rates were lower among girls. .60% of Young children aged between 5 to 10 years exhibit increased stereotyped behaviour, attachment to certain TV programs and other electronic devices (such as tablet, smartphone) more often and for longer periods of the day, temper tantrums, and crying and screaming for no obvious reasons as well as difficulty sleeping alone and frequent awakenings. 10% of children complained of psychosomatic symptoms, such as tummy pains, and diarrhoea. 16% of Adolescents had been found to have significantly higher rates of aggressive and antisocial behaviour when trying to switch them from one activity to another. Conclusions: Children with existing behavioural problems and those with ASD in particular had faced additional social and educational challenges during their special education years and had experienced the most negative consequences of living in a stressful situation like home lockdown, and are therefore had been particularly hard hit. COVD-19 pandemic was a neglected medical cause of deteriorating child behaviour, and the acute and chronic effects of this pandemic on these children’s health and education are among the greatest child harms of the 21st century.
{"title":"The impact of COVID-19 Lockdown on Children with Autism Spectrum Disorder and their families in Tripoli, Libya","authors":"Adel M. Zeglam, M. Al-Ogab","doi":"10.53986/ibjm.2022.0007","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0007","url":null,"abstract":"Introduction: During COVID-19 pandemic, when social distancing becomes compulsory for all, a nation-wide school closure was implemented. The aim of this paper is to assess the impact of COVID-19 lockdown on children with ASD and their families in Tripoli, Libya. Materials and Methods: We conducted face-to-face interviews with parents of children with Autism Spectrum Disorder (ASD) during the period of the outbreak between June to December 2020. The Modified Check list of Autism in Toddlers (M-CHAT) was used to evaluate patients. Results: 250 children diagnosed of ASD were included. The prevalence of aggressive behaviour had increased by 47% that of loss of communication is 33%, that of poor interaction is 52% and that of anxiety among families is 27%, although rates were lower among girls. .60% of Young children aged between 5 to 10 years exhibit increased stereotyped behaviour, attachment to certain TV programs and other electronic devices (such as tablet, smartphone) more often and for longer periods of the day, temper tantrums, and crying and screaming for no obvious reasons as well as difficulty sleeping alone and frequent awakenings. 10% of children complained of psychosomatic symptoms, such as tummy pains, and diarrhoea. 16% of Adolescents had been found to have significantly higher rates of aggressive and antisocial behaviour when trying to switch them from one activity to another. Conclusions: Children with existing behavioural problems and those with ASD in particular had faced additional social and educational challenges during their special education years and had experienced the most negative consequences of living in a stressful situation like home lockdown, and are therefore had been particularly hard hit. COVD-19 pandemic was a neglected medical cause of deteriorating child behaviour, and the acute and chronic effects of this pandemic on these children’s health and education are among the greatest child harms of the 21st century.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75034095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulaziz Dwaya, A. Urayet, Mohamed B. Milad, Abdulhamid M. Alkout
Introduction: Urinary Tract infection (UTI) is considered as the most common infections disease among women. UTI may lead to a serious complication in both kidneys. In this study, we tried to determine whether the alternation in platelet count during UTI is related to specific Gram-type of bacteria causing the infection. This assists the medical staff in selection of suitable antimicrobial drug. Material and Methods: Data of all urine cultures from Gynecology Department/ Albaraa Hospital/Tripoli processed at the Laboratory during a period of three years (2017 - 2019). All Data analysis and statistics were made with the SPSS software version 16 and performed with one-way ANOVA and a parametric test was used for categorical values and not normally distributed values. Results: A growth was detected in 101 of 193 (52%) samples and 22 (11%) were mixed growth. Gram-negative bacteria identified in 57% (45/79) while 43% (34/79) occurred with Gram-positive bacteria. Regarding to platelets count alteration, it is revealed that there was a significant difference between cases infected by Gram-negative bacteria compared to others infected by Gram-positive bacteria and control group. Conclusions: Results of the current study suggest that the change in platelet count during UTI is associated with causative bacteria’s Gram-type.
{"title":"Platelet Count as Useful Indicator for Gram-Type of Bacteria Causing Urinary Tract Infection in Women","authors":"Abdulaziz Dwaya, A. Urayet, Mohamed B. Milad, Abdulhamid M. Alkout","doi":"10.53986/ibjm.2022.0006","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0006","url":null,"abstract":"Introduction: Urinary Tract infection (UTI) is considered as the most common infections disease among women. UTI may lead to a serious complication in both kidneys. In this study, we tried to determine whether the alternation in platelet count during UTI is related to specific Gram-type of bacteria causing the infection. This assists the medical staff in selection of suitable antimicrobial drug. Material and Methods: Data of all urine cultures from Gynecology Department/ Albaraa Hospital/Tripoli processed at the Laboratory during a period of three years (2017 - 2019). All Data analysis and statistics were made with the SPSS software version 16 and performed with one-way ANOVA and a parametric test was used for categorical values and not normally distributed values. Results: A growth was detected in 101 of 193 (52%) samples and 22 (11%) were mixed growth. Gram-negative bacteria identified in 57% (45/79) while 43% (34/79) occurred with Gram-positive bacteria. Regarding to platelets count alteration, it is revealed that there was a significant difference between cases infected by Gram-negative bacteria compared to others infected by Gram-positive bacteria and control group. Conclusions: Results of the current study suggest that the change in platelet count during UTI is associated with causative bacteria’s Gram-type.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"243 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77260104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolay Paola Ojeda-Uparela, Natalia Sofía Pancho-Villareal, Fernando Jesús Yi-Quesada, Camilo Andrés Ramírez-Salgado, Luis Felipe Arias-Guerra, M. G. Ortega-Sierra, M. M. Rahman
Morning surge blood pressure as a phenotype of systemic hemodynamic atherothrombotic syndrome Carolay Paola Ojeda-Uparela a , Natalia Sofía Pancho-Villareal , Fernando Jesús YiQuesada , Camilo Andrés Ramírez-Salgado , Luis Felipe Arias-Guerra , Michael Gregorio Ortega-Sierra , Md Moshiur Rahman f,* a Department of Medicine, School of Medicine, Universidad Libre, Barranquilla, Colombia b Department of Medicine, School of Medicine, Universidad Cooperativa de Colombia, Pasto, Colombia c Department of Medicine, School of Medicine, Universidad Simón Bolivar, Barranquilla, Colombia d Department of Medicine, School of Medicine, Universidad de Sucre, Sincelejo, Colombia e Medical and Surgical Research Center, St Mary's Medical Group, Cartagena, Colombia f Department of Neurosurgery, Holy Family Red Crescent Medical College, Dhaka, Bangladesh
晨起血压升高作为全身性血流动力学动脉粥样硬化综合征的一种表型Carolay Paola Ojeda-Uparela a, Natalia Sofía Pancho-Villareal, Fernando Jesús YiQuesada, Camilo andrs Ramírez-Salgado, Luis Felipe Arias-Guerra, Michael Gregorio Ortega-Sierra, Md Moshiur Rahman f，* a哥伦比亚巴兰基利亚自由大学医学院医学系b哥伦比亚合作大学医学院医学系，Pasto，哥伦比亚c哥伦比亚巴兰基利亚玻利瓦尔大学医学院医学系Simón哥伦比亚巴兰基利亚玻利瓦尔大学医学系d哥伦比亚苏克雷大学医学院医学部医学系e哥伦比亚卡塔赫纳圣玛丽医疗集团医学和外科研究中心f孟加拉国达卡圣家族红新月医学院神经外科学系
{"title":"Morning surge blood pressure as a phenotype of systemic hemodynamic atherothrombotic syndrome","authors":"Carolay Paola Ojeda-Uparela, Natalia Sofía Pancho-Villareal, Fernando Jesús Yi-Quesada, Camilo Andrés Ramírez-Salgado, Luis Felipe Arias-Guerra, M. G. Ortega-Sierra, M. M. Rahman","doi":"10.53986/ibjm.2022.0005","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0005","url":null,"abstract":"Morning surge blood pressure as a phenotype of systemic hemodynamic atherothrombotic syndrome Carolay Paola Ojeda-Uparela a , Natalia Sofía Pancho-Villareal , Fernando Jesús YiQuesada , Camilo Andrés Ramírez-Salgado , Luis Felipe Arias-Guerra , Michael Gregorio Ortega-Sierra , Md Moshiur Rahman f,* a Department of Medicine, School of Medicine, Universidad Libre, Barranquilla, Colombia b Department of Medicine, School of Medicine, Universidad Cooperativa de Colombia, Pasto, Colombia c Department of Medicine, School of Medicine, Universidad Simón Bolivar, Barranquilla, Colombia d Department of Medicine, School of Medicine, Universidad de Sucre, Sincelejo, Colombia e Medical and Surgical Research Center, St Mary's Medical Group, Cartagena, Colombia f Department of Neurosurgery, Holy Family Red Crescent Medical College, Dhaka, Bangladesh","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"50 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72547140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mucormycosis is rare in both immunocompromised and immunocompetent patients. A Chronic Myelomonocytic Leukaemia (CMML) is among the most aggressive and poorly understood chronic myeloid malignancies, and Mucormycosis is an uncommonly encountered clinical syndrome in immunocompromised hematology patients. Patients treated with mechanical ventilation are at a substantially higher risk for infection. Also, the patients who are using home respirator devices at high risk for mucormycosis. Patients must be informed in detail about the device and its proper use. Additionally, all immunocompromised patients should be informed about the protection of the respiratory tract. Dirty or contaminated equipment are potential sources of infection. All devices and accessories should be cleaned regularly. The tubes should also be checked frequently to ensure that they are safely connected. The purpose of this case is to report an uncommon case of pulmonary mucormycosis related to the use of the home-ventilator device.
{"title":"A Pulmonary Mucormycosis Case Related to the Use of Home-Ventilator Machine","authors":"C. Özlü, Ü. Ergene, S. Alkan","doi":"10.53986/ibjm.2022.0003","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0003","url":null,"abstract":"Mucormycosis is rare in both immunocompromised and immunocompetent patients. A Chronic Myelomonocytic Leukaemia (CMML) is among the most aggressive and poorly understood chronic myeloid malignancies, and Mucormycosis is an uncommonly encountered clinical syndrome in immunocompromised hematology patients. Patients treated with mechanical ventilation are at a substantially higher risk for infection. Also, the patients who are using home respirator devices at high risk for mucormycosis. Patients must be informed in detail about the device and its proper use. Additionally, all immunocompromised patients should be informed about the protection of the respiratory tract. Dirty or contaminated equipment are potential sources of infection. All devices and accessories should be cleaned regularly. The tubes should also be checked frequently to ensure that they are safely connected. The purpose of this case is to report an uncommon case of pulmonary mucormycosis related to the use of the home-ventilator device.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75134837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Pressure ulcers (PU) are a major health problem, causing increased health costs as well as workload of health workers. In this study, we aimed to analyze the developments in PUs and to add perspective to future studies by examining the research articles published on PUs, which is an increasing health problem worldwide. Material and methods: Bibliometric analysis method was used in this study. The data was obtained by searching the Elsevier Scopus database with using the keywords “pressure ulcer” or “bedsore” or “decubitus ulcer” or “decubitus” or “pressure sore”. Results: 4,361 articles were analyzed in terms of study criteria. The first article was published in the year 1849 and 52.94 % of articles were published after the year 2011. Most of the articles were written in English (87.6%) language. The majority 29.32%) of articles were from the United States of America (USA). USA, United Kingdom and Japan were the top three publishing countries. Most of the articles were in the area of medicine [n =2896(66.4%)] and nursing [n=1903(43.63%)]. The highest number of articles on PUs were published in the journals of Ostomy Wound Management (n=177), Journal of Wound Care (n=156), International Wound Journal (n=144), Journal of Wound Ostomy And Continence Nursing (n=141) and Journal of Tissue Viability (n=126). Conclusions: As the number of immobile and debiliated patients increase globally, the publications on PUs seem to be increase too. Studies outside of Europe and the USA should also be supported and the number of publications should be increased, especially from developing countries.
{"title":"Overview on pressure ulcers studies based on bibliometric methods","authors":"Hatice Öntürk Akyüz, Sevda Alkan, Oruç Numan Gökçe","doi":"10.53986/ibjm.2022.0004","DOIUrl":"https://doi.org/10.53986/ibjm.2022.0004","url":null,"abstract":"Introduction: Pressure ulcers (PU) are a major health problem, causing increased health costs as well as workload of health workers. In this study, we aimed to analyze the developments in PUs and to add perspective to future studies by examining the research articles published on PUs, which is an increasing health problem worldwide. Material and methods: Bibliometric analysis method was used in this study. The data was obtained by searching the Elsevier Scopus database with using the keywords “pressure ulcer” or “bedsore” or “decubitus ulcer” or “decubitus” or “pressure sore”. Results: 4,361 articles were analyzed in terms of study criteria. The first article was published in the year 1849 and 52.94 % of articles were published after the year 2011. Most of the articles were written in English (87.6%) language. The majority 29.32%) of articles were from the United States of America (USA). USA, United Kingdom and Japan were the top three publishing countries. Most of the articles were in the area of medicine [n =2896(66.4%)] and nursing [n=1903(43.63%)]. The highest number of articles on PUs were published in the journals of Ostomy Wound Management (n=177), Journal of Wound Care (n=156), International Wound Journal (n=144), Journal of Wound Ostomy And Continence Nursing (n=141) and Journal of Tissue Viability (n=126). Conclusions: As the number of immobile and debiliated patients increase globally, the publications on PUs seem to be increase too. Studies outside of Europe and the USA should also be supported and the number of publications should be increased, especially from developing countries.","PeriodicalId":13190,"journal":{"name":"Iberoamerican Journal of Medicine","volume":"199 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80048984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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