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Assessment of quality of life among head-and-neck cancer patients 头颈癌患者生活质量评价
Pub Date : 2021-12-17 DOI: 10.25259/ijms_344_2021
Afsana Nizar, B. R. Isaac
To assess QOL of different head and neck cancer patients.A cross sectional study of 35 subjects with HNC was selected based on the type of cancer. After a background study, 35 subjects were chosen classifying on the type of cancer and were assessed using an interview schedule.Physical as well as emotional score was poor among the group (312.5 and 349.5). The results had a high degree of variation.QOL among HNC patients were concluded to be poor.
目的:评价不同类型头颈部肿瘤患者的生活质量。根据癌症类型选择了35名HNC患者的横断面研究。在背景研究之后,根据癌症的类型选择了35名受试者,并通过访谈时间表对其进行评估。他们的身体和情绪得分都很低(分别为312.5分和349.5分)。结果有很大的差异。HNC患者的生活质量较差。
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引用次数: 0
Determinants of quality of life among COVID-19 patients in Southwestern region of Bangladesh 孟加拉国西南地区COVID-19患者生活质量的决定因素
Pub Date : 2021-12-06 DOI: 10.25259/ijms_337_2021
Md. Injamul Haq Methun, M. G. Uddin, Iqramul Haq, Md Asaduzzaman Noor, M. Habib, Md. Ismail Hossain, A. Saleheen, S. Roy, Shatabdi Shamrita Ume, Md. Rukonozzaman Rukon, Md. Amit Hasan, Md. jahangir Alam
The outbreak of COVID-19 has caused an unprecedented health crisis and dramatically changed human lives. This study aims to identify risk factors related to health-related quality of life (HRQoL) among COVID-19 patients who were discharged from the hospital.A total of 557 COVID-19 patients of Jhenaidah district of Bangladesh who had tested positive before February 1 of 2021 were selected for this cross-sectional study. The EuroQol 5-dimensional-5 level questionnaire was used to measure the HRQoL. Thai value set was used to assess the full health status. Chi-square test was used to find out the association of HRQoL with sociodemographic and clinical factors. Finally, logistic regression was used to find out the predictors of the dimensions of HRQoL.Using the Thai value set, it is observed that 57.27% of participants had reported that they had experienced moderate or severe health problems. About 40.57% of the respondent reported anxiety or depression, whereas 39.14% of the participants had experienced moderate or severe pain or discomfort. The result of the logistic regression showed that age, gender, occupation, place of care, heart problems, and diabetes significantly affect various dimensions of the HRQoL.The COVID-19 significantly depletes the health condition of the patients in both mental and physical aspects. Therefore, the policy-makers and government should need to come with comprehensive strategies to reduce the psychological and physical health woe of COVID-19 patients.
新冠肺炎疫情引发了前所未有的健康危机,极大地改变了人类的生活。本研究旨在确定与出院的COVID-19患者健康相关生活质量(HRQoL)相关的危险因素。本横断面研究选择了2021年2月1日之前孟加拉国吉纳伊达地区检测呈阳性的557例COVID-19患者。采用EuroQol 5维5级问卷测量HRQoL。使用泰国值集评估完全健康状态。采用卡方检验探讨HRQoL与社会人口学及临床因素的相关性。最后,采用logistic回归分析找出影响HRQoL各维度的预测因子。使用泰国值集,可以观察到57.27%的参与者报告说他们经历过中度或严重的健康问题。约40.57%的受访者表示焦虑或抑郁,而39.14%的参与者经历过中度或重度疼痛或不适。logistic回归分析结果显示,年龄、性别、职业、就诊地点、心脏问题、糖尿病对HRQoL各维度均有显著影响。新冠肺炎严重损害了患者的身心健康状况。因此,政策制定者和政府应该制定全面的战略,以减少新冠肺炎患者的心理和身体健康痛苦。
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引用次数: 0
Alcohol-based hand sanitizer-induced burns: A harsh reality in current times 含酒精的洗手液引起的烧伤:当今时代的残酷现实
Pub Date : 2021-11-22 DOI: 10.25259/ijms_365_2021
D. Gupta, Amrita More
Due to the recent coronavirus pandemic, there is a steep rise in the use of alcohol-based hand sanitizers (ABHSs) over the past few months. For them to be effective against microorganisms, the minimum recommended concentration of alcohol is 60%. This high alcohol content makes the sanitizers easily flammable. Although, they are extremely convenient to use, they can also prove to be a hazard if used in an improper manner. Guidelines have been published for safe manufacturing and distribution of these sanitizers. There are recommendations for storage and use, which should be adhered to in a strict manner. Their use by children should always be supervised. We report four cases of burn injuries caused by injudicious use of alcohol-based sanitizers. The flammable nature of ABHSs can also be exploited as witnessed in one of our cases. With this report, we wish to emphasize that judicious and correct use of these seemingly benign products is essential.
由于最近的冠状病毒大流行,在过去几个月里,含酒精的洗手液(abhs)的使用急剧增加。为了使它们对微生物有效,建议的最低酒精浓度为60%。这种高酒精含量使消毒液容易易燃。虽然它们使用起来非常方便,但如果使用不当,它们也可能被证明是一种危险。已经发布了安全生产和分发这些消毒剂的指南。有储存和使用的建议,应严格遵守。儿童使用时应经常受到监督。我们报告四个病例烧伤造成不明智的使用酒精为基础的消毒剂。在我们的一个案例中,abhs的可燃性也可以被利用。在这份报告中,我们希望强调,明智和正确使用这些看似无害的产品是至关重要的。
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引用次数: 0
Knowledge, attitude, and prevention of self-medication practices among the general population of Gujarat 古吉拉特邦普通民众自我药疗实践的知识、态度和预防
Pub Date : 2021-11-22 DOI: 10.25259/ijms_354_2021
H. Shah, B. Arora
The practice of self-medication (SM) without consulting a health-care professional among the populace of both developed and developing countries like India may lead to a delay in therapeutic effectiveness. The present study was conducted to assess the knowledge, attitude, and practice of SM among the general population of Gujarat.An observational, cross-sectional questionnaire-based study was conducted among 488 participants between April 2021 and May 2021 to evaluate the several aspects of SM. In April 2021, this study was conducted on both the genders of 18–80 years of urban and rural areas of Gujarat. Data were analyzed for descriptive statistics. The data presented in the form of percentages using tables and figures. The responses were collected and analyzed using GraphPad v.8 and Microsoft Excel for percentage and statistical significance.Prevalence of SM was 78.3%. It was found to be practiced more among the younger age group (55.32%) than the older. Graduates practiced SM more than the others (P < 0.004). Significant association was found between its practice and residency (P < 0.03), marital status (P < 0.003), education (P < 0.004), and occupation (P < 0.0007). Fever, cough, and cold were the most common conditions noted for SM practice followed by headache. It was noticed that 63.5% participants were procured medications from pharmacy. Multivitamins, nonsteroidal anti-inflammatory drugs, and antibiotics were the most frequent medications used by participants.The prevalence of SM is alarming which causes serious health issues and needs an intervention. Planning of health awareness programs, educating people, and pharmacists are necessary for promoting rational use of medication.
在发达国家和印度等发展中国家的民众中,没有咨询保健专业人员就自行用药的做法可能会导致治疗效果的延迟。本研究旨在评估古吉拉特邦普通人群中SM的知识、态度和实践。在2021年4月至2021年5月期间,对488名参与者进行了一项基于横断面问卷的观察性研究,以评估SM的几个方面。2021年4月,这项研究对古吉拉特邦城市和农村地区18-80岁的男女进行了研究。对数据进行描述性统计分析。数据采用表格和数字以百分比形式呈现。收集回复并使用GraphPad v.8和Microsoft Excel进行百分比和统计显著性分析。SM患病率为78.3%。研究发现,较年轻的年龄组(55.32%)比较年长的年龄组更常使用这种方法。大学毕业生的SM实践多于其他学生(P < 0.004)。医师执业与住院医师(P < 0.03)、婚姻状况(P < 0.003)、学历(P < 0.004)、职业(P < 0.0007)有显著相关。发烧、咳嗽和感冒是SM实践中最常见的症状,其次是头痛。值得注意的是,63.5%的参与者从药房购买药物。多种维生素、非甾体抗炎药和抗生素是参与者最常用的药物。性行为的流行令人震惊,它造成了严重的健康问题,需要进行干预。规划健康意识项目、教育民众和药师是促进合理用药的必要条件。
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引用次数: 0
Brain stem auditory evoked potential response in neonates after recovery from hyperbilirubinemia: A neurophysiological approach to screening neuronal hearing loss 新生儿从高胆红素血症恢复后的脑干听觉诱发电位反应:筛选神经性听力损失的神经生理学方法
Pub Date : 2021-11-20 DOI: 10.25259/ijms_342_2021
R. Yadav, L. Yadav, Pujan Bhusal, Sameer Timilsina, Niraj Sapkota, Md. Nazrul Islam
Neonatal hyperbilirubinemia leads to neurological damages including encephalopathy and hearing loss. This study aimed to screen and evaluate the hearing loss in neonates after recovery from hyperbilirubinemia using the Brainstem evoked response audiometry (BERA) test.This cross-sectional comparative study was conducted in Physiology Department at Chitwan Medical College, Nepal. It included 20 age and sex-matched neonates recently recovered from hyperbilirubinemia and 20 normal healthy controls. The external acoustic canals of subjects were checked for any blockage or collapse before BERA testing. The BERA recordings were performed after the neonate’s natural sleep following a standard lab protocol explained by Taylor’s Evoked Potential in Clinical Testing.The BERA wave latencies were delayed with a higher number of case group neonates I (IL-75%, IR-80%), III (IIIL-70%, III R-80%), and V (VL-80%, VR-85%) than those of controls. The percentage of neonates with delayed interwave latencies was comparable between groups. The neonate’s hearing sensitivity assessed using the grades of hearing impairment by WHO revealed slight (threshold of hearing left ear [THL]-25% and threshold of hearing right ear [THR]-30%) and moderate (THL-40% and THR-35%) grades among cases whereas no impairment (THL-60% and THR-55%) in controls. The hearing thresholds were more in cases.The auditory pathway is highly sensitive to elevated serum bilirubin. BERA detects even a minute degree of hearing damage seen after complete treatment of hyperbilirubinemia. Therefore, BERA is a helpful tool in the early screening of hearing impairment in neonates. This improves prognosis by early management so that the neurosensory systems develop to their full extent and one can enjoy a normal social life.
新生儿高胆红素血症导致神经损伤,包括脑病和听力丧失。本研究旨在利用脑干诱发反应测听(BERA)试验筛选和评估新生儿高胆红素血症恢复后的听力损失。本横断面比较研究在尼泊尔奇旺医学院生理学系进行。该研究包括20名年龄和性别匹配的刚从高胆红素血症中恢复过来的新生儿和20名正常的健康对照。在进行BERA测试前,检查受试者的外耳道是否有堵塞或塌陷。贝拉记录是在新生儿自然睡眠后进行的,遵循泰勒诱发电位在临床测试中解释的标准实验室方案。与对照组相比,病例组新生儿I (IL-75%, IR-80%)、III (III -70%, III R-80%)和V (VL-80%, VR-85%)的BERA波潜伏期延迟。波间潜伏期延迟的新生儿百分比在两组之间具有可比性。根据世卫组织的听力损伤等级对新生儿的听力敏感性进行评估,发现病例中轻度(左耳听力阈值[THL]-25%,右耳听力阈值[THR]-30%)和中度(THL-40%和THR-35%)等级,而对照组中无损伤(THL-60%和THR-55%)。病例的听力阈值较高。听觉通路对血清胆红素升高高度敏感。在完全治疗高胆红素血症后,BERA甚至可以检测到一分钟程度的听力损伤。因此,BERA是早期筛查新生儿听力障碍的有用工具。这可以通过早期治疗改善预后,使神经感觉系统充分发展,使患者能够享受正常的社会生活。
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引用次数: 0
Coping with COVID-19 pandemic lockdown – The lady doctors perspective 应对COVID-19大流行的封锁——女医生的观点
Pub Date : 2021-09-24 DOI: 10.25259/ijms_319_2021
I. Aggarwal, Jaishree Ganjiwale, Aparna Parikh, N. Trivedi, Satinderbir Kaur, R. Chennamaneni, N. Choudhary, Roshni Pande, Sonal Dande, P. Iyer
This study is about the challenges faced by the women doctors in India during the first wave of the COVID-19 pandemic.We conducted an online survey in 2020 for women doctors who were professionally engaged in active patient management in India before the onset of the current pandemic.A total of 260 valid responses were received. Only 28% (73/260) were able to provide at least 50% of professional services as compared to the pre COVID-19 lockdown period. Statistically significant differences related to emotional health (feelings), physical activity, changes in how family sees the lady professional, personal free time availability, and family bonding.COVID-19 has led to the following important concerns for professional women - academic productivity; work-life balance; missed opportunities for collaborating; mental health, the need for equity-minded academic leadership, and decision-making. Our study showed that majority were stressed during the COVID-19 lockdown – with the impact being highest among those giving more than 50% of their time to professional medical services outside their homes.
这项研究是关于印度女医生在第一波COVID-19大流行期间面临的挑战。我们在2020年对当前大流行爆发前在印度从事积极患者管理专业的女医生进行了一项在线调查。我们共收到260份有效回复。只有28%(73/260)的医院能够提供至少50%的专业服务。统计上的显著差异与情绪健康(感觉)、身体活动、家庭对职业女性看法的变化、个人空闲时间的可用性和家庭关系有关。COVID-19给职业女性带来了以下重要担忧:学术生产力;工作与生活的平衡;错失合作机会;心理健康,需要公平的学术领导和决策。我们的研究表明,在COVID-19封锁期间,大多数人都感到压力很大——在那些把50%以上的时间花在家庭以外的专业医疗服务上的人身上,这种影响最大。
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引用次数: 0
The visionary who transformed private health care in India 有远见的人改变了印度的私人医疗保健
Pub Date : 2021-08-23 DOI: 10.25259/ijms_403_2021
Raju Vaishya
Dr. Prathap Chandra Reddy is the Founder-Chairman of the Apollo Hospitals Group (AHG) and is considered a living legend and architect of modern private health care in India. In 1983, Dr. Reddy started the first professionally run private hospital – Apollo Hospitals in Madras (now Chennai). Since then, the AHG has expanded to over 73 hospitals across the country. The state-of-the-art facilities have made advanced health-care services accessible and affordable to all in need. AHG has a presence in primary care, secondary care, tertiary care, quarterly care, health IT, tele-health (tele-consults, tele-pathology, tele-cardiology, and tele-radiology), eICU pharmacy retailing, project consultancy, research, and academics. He catalyzed a “reverse brain drain” by inspiring hundreds of Non-Resident Indian Doctors to come back to India, by creating opportunities and providing them with a world class medical ecosystem. Dr. Reddy’s contributions are widely recognized by patients, doctors, the health-care fraternity across the world, the community at large, and by the Government of India.
Prathap Chandra Reddy博士是阿波罗医院集团(AHG)的创始人兼董事长,被认为是印度现代私人医疗保健的传奇人物和建筑师。1983年,雷迪博士在马德拉斯(现金奈)开办了第一家专业经营的私立医院——阿波罗医院。从那时起,AHG已经扩展到全国超过73家医院。最先进的设施使所有有需要的人都能获得和负担得起先进的保健服务。AHG在初级保健、二级保健、三级保健、季度保健、卫生IT、远程保健(远程咨询、远程病理学、远程心脏病学和远程放射学)、eICU药房零售、项目咨询、研究和学术领域都有业务。他通过创造机会并为他们提供世界一流的医疗生态系统,激励数百名非居民印度医生回到印度,从而催化了一场“逆转人才流失”。Reddy博士的贡献得到了全世界病人、医生、卫生保健界、整个社会以及印度政府的广泛认可。
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引用次数: 1
Risk assessment of acquiring SARS-CoV-2 infection among employees of a tertiary cancer care center 某三级癌症护理中心工作人员SARS-CoV-2感染风险评估
Pub Date : 2021-08-21 DOI: 10.25259/ijms_194_2021
Sandeep S. Sawakare, S. Tandon, C. Pramesh, Sudeep Gupta, M. Sengar, S. Laskar, S. Nair, G. Mishra, N. Goel, S. Patkar, R. Badwe
Continuation of health-care facilities for non-COVID illness during the SARS-CoV-2 pandemic is mired with apprehension of infection to health care workers (HCWs). The lack of facilities can result in dire outcomes for patients of NCDs such as cancer. The Objective of this paper is to assess the risk of running a healthcare facility during the pandemic.A retrospective analysis was carried out at a tertiary cancer hospital to understand the quantum of risk to HCWs while providing care to patients of cancer and to SARS-CoV-2 patients, within the same set-up with optimal segregation. Data were collected for 6 weeks during which attendance, exposure, and infection status of doctors and nurses were recorded along with comorbidities.Of 1041 doctors and nurses who attended duties during the study period, 299 worked in dedicated COVID care areas while 742 worked in routine cancer care areas. The proportion of HCWs that developed symptoms or were tested positive for COVID-19 was 3.7% and 3.9%, respectively, with no statistically significant difference between the two. The proportion for the same was found to be 1.2% among the 645 staffs who were on leave. No correlation could be established between pre-existing comorbidities and risk of acquiring infection.Providing COVID care and routine specialty care within the same hospital premises do not put the HCWs at a drastically increased risk of acquiring infection subject to clear demarcation of work areas, screening at gates by trained personnel, regulation of number of hospital visitors, and optimal use of PPEs.
在SARS-CoV-2大流行期间,由于担心卫生保健工作者(HCWs)受到感染,卫生保健设施无法继续用于治疗非covid - 19疾病。设施的缺乏可能会给癌症等非传染性疾病患者带来可怕的后果。本文的目的是评估在大流行期间运行医疗机构的风险。在一家三级肿瘤医院进行了回顾性分析,以了解卫生保健人员在为癌症患者和SARS-CoV-2患者提供护理的同时,在最佳隔离的同一设置中所面临的风险量。收集了6周的数据,在此期间记录了医生和护士的就诊情况、暴露情况和感染状况以及合并症。在研究期间值班的1041名医生和护士中,299名在专门的COVID护理领域工作,742名在常规癌症护理领域工作。出现症状或COVID-19检测阳性的医护人员比例分别为3.7%和3.9%,两者之间无统计学差异。在645名休假员工中,这一比例为1.2%。未发现存在的合并症与感染风险之间存在相关性。在同一医院场所内提供COVID护理和常规专科护理不会使卫生保健工作者面临急剧增加的感染风险,前提是明确划分工作区域,由训练有素的人员在门口进行筛查,规范医院访客人数,并最佳地使用ppe。
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引用次数: 0
“Mucormycosis” and coronavirus disease 2019: An epidemic within the larger pandemic 2019年“毛霉病”和冠状病毒病:大流行中的流行病
Pub Date : 2021-08-21 DOI: 10.25259/ijms_234_2021
Sangeeta Shukla, Manisha Gupta, N. Agarwal, R. Shukla
India is passing through a significant impact of Wuhan origin coronavirus disease 2019 (COVID-19) pandemic in the second wave. Mucormycosis is emerging as a larger problem for our patients as compared to the first wave. Several plausible explanations have been put forth –but none has been proven as yet. We herein report eight cases of COVID-19-associated rhino-orbital mucormycosis diagnosed and managed at our center. We observed a higher risk among middle-aged men, with known or covert diabetes who received high-dose steroids and/or prolonged oxygen for COVID-19 management.
印度正在经历第二波武汉冠状病毒病(COVID-19)大流行的重大影响。与第一波相比,毛霉病对我们的病人来说是一个更大的问题。人们提出了几种似是而非的解释,但没有一种得到证实。我们在此报告8例在我中心诊断和治疗的与covid -19相关的鼻-眶毛霉菌病。我们观察到,患有已知或隐性糖尿病的中年男性接受大剂量类固醇和/或长时间吸氧治疗COVID-19的风险更高。
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引用次数: 0
Management of gender incongruence and gender affirmation surgeries – The Indian perspective, from a large volume gender identity clinic 性别不一致和性别确认手术的管理-从印度的角度来看,从一个大容量的性别认同诊所
Pub Date : 2021-07-10 DOI: 10.25259/IJMS_494_2020
Richie Gupta, Rajat Gupta
A mismatch between the birth sex of a person and psychological recognition of self (gender) leads to a gender expression, which is at variance with the societal norms, and thus gives rise to a persistent distress, which is known as gender incongruence (GI) (previously gender dysphoria). These persons are known as trans genders. A subset of these individuals feels that they are trapped in the wrong sexed body and need to bring their physical sex into alignment with their gender. The “gender” is already imprinted into the brain at birth, and hence cannot be changed, but the physical sex of a person can be, through gender affirmation surgeries (GAS). There has been relative paucity of data from India regarding medical and surgical affirmative management of trans-persons, and hence, the authors present their experience in GAS together with current demography, hypothesis regarding etiology and management, as carried out in India. Authors have been providing comprehensive affirmative management to trans persons, through their multi-specialty gender identity clinic (GIC) sited in a tertiary care hospital. Over past 27 years, the senior author has performed over 3,000 GAS. The authors have noticed a 20- fold rise in presentation of these cases (from six cases per year in 1993 to now around 150 cases in the year 2019), an observation, which is similar to the experience of large volume GICs worldwide, as well as many recent publications. There has been a steep rise in the number of persons with GI worldwide, and those reporting at GICs. In the face of this rising number, authors present their experience, together with current demographics and management. Authors have also contributed to the first version of Indian Standards of Care for persons with GI and people with differences in sexual development/orientation Indian standards of care 1in November 2020.
一个人的出生性别与对自我(性别)的心理认知之间的不匹配导致性别表达与社会规范不一致,从而产生持续的痛苦,这被称为性别不一致(GI)(以前的性别不安)。这些人被称为跨性别者。这些人中的一部分人觉得他们被困在错误的性别身体里,需要让他们的生理性别与他们的性别保持一致。“性别”在出生时就已经烙印在大脑中,因此无法改变,但一个人的生理性别可以通过性别确认手术(GAS)来改变。来自印度的关于跨性别者的医疗和手术积极管理的数据相对缺乏,因此,作者介绍了他们在印度进行的跨性别者治疗方面的经验,以及目前的人口统计、关于病因和管理的假设。作者通过位于三级护理医院的多专业性别认同诊所(GIC),一直在为跨性别者提供全面的平权管理。在过去的27年里,资深作者已经执行了3000多次GAS。作者注意到这些病例的报告增加了20倍(从1993年的每年6例增加到现在的2019年约150例),这一观察结果与世界范围内大量gic的经验以及许多最近的出版物相似。全球患有GI的人数以及在GI报告的人数急剧上升。面对这个不断增长的数字,作者介绍了他们的经验,以及目前的人口统计和管理。作者还为2020年11月发布的《印度GI患者和性发展/性取向差异患者护理标准》第一版做出了贡献。
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引用次数: 0
期刊
Indian journal of medical sciences
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