The lifestyle diseases which are becoming chronic noncommunicable disorders contribute to about 53% of death rate in India affecting the DALY to a greater extent. These lifestyle illnesses are proving to be a great challenge in public health as they are necessitating for the advanced modalities of screening techniques that have to be in place for early detection. The objectives of the study were to assess the prevalence and determinants of chronic illness and quality of life among rural residents of Pondicherry. The study is a descriptive observational study using a validated structured questionnaire among rural residents who have crossed the adolescent period. The subjects included people aged above 18 years. It is observed that about 45.5% of the study population are between 38 and 58 years and about 24% of the study population were skilled, 10.6% are illiterate and 59.8% of the study population are not regular visitors to any health center, about 72% of them attend a health facility once in 3- 5–7 months/year. It is observed that about 24.6% have had the disease for 6–10 years. Among them, 25.9% are diabetic, 7.3% are hypertensive, 8% have both, 3.7% had asthma, 0.3% are CAD, and 0.7% had a stroke. According to physical (median = 26), psychological (median = 21), social (median = 11), and environmental (median = 29) domains, quality of life was moderately good. This study revealed that all the domains are affected in the quality of life even in a rural area where urbanisation and industrialisation is not establihed.
{"title":"Prevalence and determinants of chronic illness and quality of life among rural residents of Pondicherry - A descriptive cross-sectional study","authors":"Mani Mercy Jafrin","doi":"10.25259/ijms_102_2022","DOIUrl":"https://doi.org/10.25259/ijms_102_2022","url":null,"abstract":"\u0000\u0000The lifestyle diseases which are becoming chronic noncommunicable disorders contribute to about 53% of death rate in India affecting the DALY to a greater extent. These lifestyle illnesses are proving to be a great challenge in public health as they are necessitating for the advanced modalities of screening techniques that have to be in place for early detection. The objectives of the study were to assess the prevalence and determinants of chronic illness and quality of life among rural residents of Pondicherry.\u0000\u0000\u0000\u0000The study is a descriptive observational study using a validated structured questionnaire among rural residents who have crossed the adolescent period.\u0000\u0000\u0000\u0000The subjects included people aged above 18 years. It is observed that about 45.5% of the study population are between 38 and 58 years and about 24% of the study population were skilled, 10.6% are illiterate and 59.8% of the study population are not regular visitors to any health center, about 72% of them attend a health facility once in 3- 5–7 months/year. It is observed that about 24.6% have had the disease for 6–10 years. Among them, 25.9% are diabetic, 7.3% are hypertensive, 8% have both, 3.7% had asthma, 0.3% are CAD, and 0.7% had a stroke. According to physical (median = 26), psychological (median = 21), social (median = 11), and environmental (median = 29) domains, quality of life was moderately good.\u0000\u0000\u0000\u0000This study revealed that all the domains are affected in the quality of life even in a rural area where urbanisation and industrialisation is not establihed.\u0000","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82768183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence and ChatGPT in the legal context","authors":"P. Gandhi, V. Talwar","doi":"10.25259/ijms_34_2023","DOIUrl":"https://doi.org/10.25259/ijms_34_2023","url":null,"abstract":"","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91166014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purvish M. Parikh, Dinesh M. Shah, Kairav P. Parikh
Chat Generative Pre-Trained Transformer (ChatGPT) has revolutionized how we perceive artificial intelligence (AI).: Judge Juan Manuel Padilla Garcia created history by mentioning its use while passing judgment about an autistic child and payment for his medical treatment by his insurance company. The use of AI is not new and is helping the judiciary system in many ways. However, this judgment given on January 30, 2023, has ignited controversy among Judge Garcia’s peers and the global community (a Google search produced more than 70 million hits on February 5, 2023). EU has established guidelines that are to be followed before calling any AI tool trustworthy. This requires stringent compliance with the verification and due diligence process. In this instance, ChatGPT was used within 2 months of its launch, even when it has been shown to give incomplete, incorrect, and misleading answers in many instances. Hasty adaption of unproven technology, however good it may be, should not be our path. This might fuel the misguided fear amongst people about robots taking over from human judges.
聊天生成预训练转换器(ChatGPT)彻底改变了我们对人工智能(AI)的看法。当前位置法官胡安·曼努埃尔·帕迪拉·加西亚(Juan Manuel Padilla Garcia)在对一名自闭症儿童及其保险公司支付医疗费用的案件作出判决时，提到了它的使用，创造了历史。人工智能的使用并不新鲜，它在很多方面都在帮助司法系统。然而，这一判决于2023年1月30日作出，在加西亚法官的同行和全球社会中引发了争议(2023年2月5日，谷歌搜索产生了7000多万次点击)。在称任何人工智能工具值得信赖之前，欧盟已经制定了需要遵循的指导方针。这需要严格遵守核查和尽职调查过程。在这个例子中，ChatGPT在发布后2个月内就被使用了，即使它在许多情况下给出了不完整、不正确和误导性的答案。仓促采用未经验证的技术，不管它有多好，都不应该成为我们的道路。这可能会加剧人们对机器人取代人类法官的错误恐惧。
{"title":"Judge Juan Manuel Padilla Garcia, ChatGPT, and a controversial medicolegal milestone","authors":"Purvish M. Parikh, Dinesh M. Shah, Kairav P. Parikh","doi":"10.25259/ijms_31_2023","DOIUrl":"https://doi.org/10.25259/ijms_31_2023","url":null,"abstract":"Chat Generative Pre-Trained Transformer (ChatGPT) has revolutionized how we perceive artificial intelligence (AI).: Judge Juan Manuel Padilla Garcia created history by mentioning its use while passing judgment about an autistic child and payment for his medical treatment by his insurance company. The use of AI is not new and is helping the judiciary system in many ways. However, this judgment given on January 30, 2023, has ignited controversy among Judge Garcia’s peers and the global community (a Google search produced more than 70 million hits on February 5, 2023). EU has established guidelines that are to be followed before calling any AI tool trustworthy. This requires stringent compliance with the verification and due diligence process. In this instance, ChatGPT was used within 2 months of its launch, even when it has been shown to give incomplete, incorrect, and misleading answers in many instances. Hasty adaption of unproven technology, however good it may be, should not be our path. This might fuel the misguided fear amongst people about robots taking over from human judges.","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81776980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cerebellar ataxic syndromes, although uncommon, have been reported previously in patients taking metronidazole. However, almost all cases describe instances where patients were taking prolonged or high doses of the drug. We report a 65-year-old man who consumed 400 mg of metronidazole 3 times over 1 day and presented with slurring of speech, imbalance while walking and diplopia. The symptoms developed the day after consumption of metronidazole. Examination showed slurring of speech, gaze-evoked nystagmus, and dysmetria in all limbs. MRI brain revealed symmetric hyperintense lesions in the dentate nucleus and pons on T2-weighted imaging and FLAIR, which have a well-established association with metronidazole-induced central nervous system (CNS) toxicity. On discontinuation of the drug, symptoms improved, and complete recovery was noted at follow-up 2 weeks later. This case indicates that CNS side effects of metronidazole may not necessarily occur only at high doses or after prolonged courses of metronidazole, but may occur as an idiosyncratic reaction to the drug. Reasons for variable susceptibility require further investigation.
{"title":"Cerebellar ataxia after a single day of metronidazole use: Case report","authors":"S. Parekh, M. Dsouza, S. Bhaisare, Arshad Abdulla","doi":"10.25259/ijms_272_2022","DOIUrl":"https://doi.org/10.25259/ijms_272_2022","url":null,"abstract":"Cerebellar ataxic syndromes, although uncommon, have been reported previously in patients taking metronidazole. However, almost all cases describe instances where patients were taking prolonged or high doses of the drug. We report a 65-year-old man who consumed 400 mg of metronidazole 3 times over 1 day and presented with slurring of speech, imbalance while walking and diplopia. The symptoms developed the day after consumption of metronidazole. Examination showed slurring of speech, gaze-evoked nystagmus, and dysmetria in all limbs. MRI brain revealed symmetric hyperintense lesions in the dentate nucleus and pons on T2-weighted imaging and FLAIR, which have a well-established association with metronidazole-induced central nervous system (CNS) toxicity. On discontinuation of the drug, symptoms improved, and complete recovery was noted at follow-up 2 weeks later. This case indicates that CNS side effects of metronidazole may not necessarily occur only at high doses or after prolonged courses of metronidazole, but may occur as an idiosyncratic reaction to the drug. Reasons for variable susceptibility require further investigation.","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79073593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sanjana Rameshkumar, S. Viswanathan, A. R. Jagadeesan, Yallakanti Dhanunjaya
Iron deficiency anemia (IDA) is the most common nutritional deficiency among pregnant women in India. Iron can be supplemented orally or intravenously to treat IDA. Intravenous supplementation of iron can be risky as there is more possibility for the production of free iron in circulation. The role of free iron in the generation of free radicals and thereby oxidative stress is well known. The present study tends to evaluate oxidative stress and antioxidant status of intravenous iron sucrose treated pregnant women. This prospective study was conducted in ACS Medical College and Hospital, Chennai. Twenty pregnant women with moderate IDA (Hb: 7–9.9 g/dl) were included in the present study. Blood samples were collected before and after the treatment with intravenous iron sucrose to measure antioxidants such as reduced glutathione, catalase and superoxide dismutase, and lipid peroxidation marker such as malondialdehyde. In the present study, plasma malondialdehyde levels were increased significantly after the treatment with intravenous iron sucrose. No significant alterations were observed in the levels of reduced glutathione and activities of catalase and superoxide dismutase. In the present study, intravenous iron sucrose infusion was associated with oxidative stress as evidenced by increased lipid peroxidation in antenatal women with IDA. Hence, treatment with antioxidants during iron infusions can be considered.
{"title":"A pilot study on effect of intravenous iron sucrose on oxidative stress and antioxidant status of pregnant women with iron deficiency anemia","authors":"Sanjana Rameshkumar, S. Viswanathan, A. R. Jagadeesan, Yallakanti Dhanunjaya","doi":"10.25259/ijms_402_2021","DOIUrl":"https://doi.org/10.25259/ijms_402_2021","url":null,"abstract":"\u0000\u0000Iron deficiency anemia (IDA) is the most common nutritional deficiency among pregnant women in India. Iron can be supplemented orally or intravenously to treat IDA. Intravenous supplementation of iron can be risky as there is more possibility for the production of free iron in circulation. The role of free iron in the generation of free radicals and thereby oxidative stress is well known. The present study tends to evaluate oxidative stress and antioxidant status of intravenous iron sucrose treated pregnant women.\u0000\u0000\u0000\u0000This prospective study was conducted in ACS Medical College and Hospital, Chennai. Twenty pregnant women with moderate IDA (Hb: 7–9.9 g/dl) were included in the present study. Blood samples were collected before and after the treatment with intravenous iron sucrose to measure antioxidants such as reduced glutathione, catalase and superoxide dismutase, and lipid peroxidation marker such as malondialdehyde.\u0000\u0000\u0000\u0000In the present study, plasma malondialdehyde levels were increased significantly after the treatment with intravenous iron sucrose. No significant alterations were observed in the levels of reduced glutathione and activities of catalase and superoxide dismutase.\u0000\u0000\u0000\u0000In the present study, intravenous iron sucrose infusion was associated with oxidative stress as evidenced by increased lipid peroxidation in antenatal women with IDA. Hence, treatment with antioxidants during iron infusions can be considered.\u0000","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"os-46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87354436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Perception about radiology as a medical subspecialty among secondary school students","authors":"Bhuvan Botchu, Molly Rennie, R. Botchu","doi":"10.25259/ijms_222_2022","DOIUrl":"https://doi.org/10.25259/ijms_222_2022","url":null,"abstract":"","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90496237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Body mass index (BMI) is a traditional measurement practice that divides a person’s weight by their height to find out whether they have a healthy range of weight. The objective of this study is to understand the relation between BMI and prevalence of diabetes mellitus, hypertension, and dyslipidemia. BMI distribution among these patients was compared with and without hypertension and dyslipidemia. The improper of secretion of insulin leads to changes in metabolism of lipids, proteins, and carbohydrates also characterized hyperglycemia generally considered as diabetes mellitus (DM). The excessive formation of free radicals induces oxidative stress, and the antioxidant defense system becomes weaken and hence arises diabetic disorder and overproduction of malondialdehyde (MDA). In cells, the polyunsaturated fatty acid peroxidation is considered as the final product and marker of oxidative stress. In this study, significantly increased BMI is observed in diabetic victims in comparison with control group. A significant positive correlation was noticed between glycated hemoglobin, cholesterol, and MDA. In conclusion, for the prevention and management of vascular complication in type 2 diabetes mellitus, maintaining normal levels of MDA and body weight are very important. Further large-scale studies are required to confirm it.
{"title":"A correlation biomarker between BMI and lipid peroxidation in type 2 diabetes mellitus with and without other complications","authors":"G. Premkumar, V. Bhagyalakshmi, S. Sandhya","doi":"10.25259/ijms_359_2021","DOIUrl":"https://doi.org/10.25259/ijms_359_2021","url":null,"abstract":"\u0000\u0000Body mass index (BMI) is a traditional measurement practice that divides a person’s weight by their height to find out whether they have a healthy range of weight. The objective of this study is to understand the relation between BMI and prevalence of diabetes mellitus, hypertension, and dyslipidemia.\u0000\u0000\u0000\u0000BMI distribution among these patients was compared with and without hypertension and dyslipidemia. The improper of secretion of insulin leads to changes in metabolism of lipids, proteins, and carbohydrates also characterized hyperglycemia generally considered as diabetes mellitus (DM).\u0000\u0000\u0000\u0000The excessive formation of free radicals induces oxidative stress, and the antioxidant defense system becomes weaken and hence arises diabetic disorder and overproduction of malondialdehyde (MDA). In cells, the polyunsaturated fatty acid peroxidation is considered as the final product and marker of oxidative stress.\u0000\u0000\u0000\u0000In this study, significantly increased BMI is observed in diabetic victims in comparison with control group. A significant positive correlation was noticed between glycated hemoglobin, cholesterol, and MDA. In conclusion, for the prevention and management of vascular complication in type 2 diabetes mellitus, maintaining normal levels of MDA and body weight are very important. Further large-scale studies are required to confirm it.\u0000","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79286227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Who are the real parasite publishers and journals? What prevents all medical data from being open access in real-time?","authors":"P. Parikh, A. Vora","doi":"10.25259/ijms_283_2022","DOIUrl":"https://doi.org/10.25259/ijms_283_2022","url":null,"abstract":"","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"96 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74402665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thrombus in transit (TIT) is a rare but potentially fatal condition. Transthoracic echocardiography is the diagnostic modality of choice. The major complications of TIT are pulmonary embolism, right ventricular dysfunction, obstructive shock, and paradoxical embolism through patent foramen ovale. We hereby present a case series of four patients with TIT and the challenges faced while managing them.
{"title":"Thrombus in transit – A case series on dilemma in management","authors":"Gyanendra Agrawal, Smita Sharma, B. Paul","doi":"10.25259/ijms_131_2022","DOIUrl":"https://doi.org/10.25259/ijms_131_2022","url":null,"abstract":"Thrombus in transit (TIT) is a rare but potentially fatal condition. Transthoracic echocardiography is the diagnostic modality of choice. The major complications of TIT are pulmonary embolism, right ventricular dysfunction, obstructive shock, and paradoxical embolism through patent foramen ovale. We hereby present a case series of four patients with TIT and the challenges faced while managing them.","PeriodicalId":13277,"journal":{"name":"Indian journal of medical sciences","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86573044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：