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Open-access publishing: Boon or bane for Indian medical researchers? 开放获取出版:印度医学研究人员的福还是祸?
Pub Date : 2022-07-28 DOI: 10.25259/ijms_375_2021
V. Dhiman, R. Tiwari
The concept of Open-Access (OA) publishing was initiated in the early 2000s with the idea to provide free, equal, and OA of scientific knowledge to all communities and countries. The article published in an OA journal is freely available on the public internet and permits any users to read, download, copy, distribute, and print. The OA articles are published much sooner and are believed to get more citations than the articles published in subscription-based journals. Since the end-user does not have to pay to read an OA article, the author usually pays Article Processing Charges (APCs) to get his/her work published in OA journals. High APCs of OA journals are usually a serious concern for medical researchers in India, which restricts them to publish in OA journals. Since most OA journals are new, they tend to have low impact factors as compared to subscription-based journals, which prevent many good researchers to get their work published in OA journals. Furthermore, predatory journals exploit the idea of OA and tend to publish poor or very low-quality research papers. This has resulted in distrust among the authors and readers that OA publishing is not peer-reviewed or has low quality. In conclusion, publishing in OA journals has both pros and cons. With the Government of India’s ambitious “One Nation, One Subscription” policy in the pipeline, medical researchers in India are hopeful that soon both access and publishing in scientific journals will be free for all in the country.
开放获取(OA)出版的概念始于21世纪初,其理念是向所有社区和国家提供免费、平等和OA的科学知识。发表在OA期刊上的文章可以在公共互联网上免费获得,并且允许任何用户阅读、下载、复制、分发和打印。OA文章发表得更快,被认为比在订阅期刊上发表的文章得到更多的引用。由于最终用户阅读OA文章不需要付费,因此作者通常需要支付文章处理费(apc)才能将其作品发表在OA期刊上。开放获取期刊的高apc通常是印度医学研究人员严重关注的问题,这限制了他们在开放获取期刊上发表文章。由于大多数开放获取期刊都是新的,与基于订阅的期刊相比,它们的影响因子往往较低,这使得许多优秀的研究人员无法在开放获取期刊上发表他们的研究成果。此外,掠夺性期刊利用开放获取的理念,倾向于发表质量很差或非常低质量的研究论文。这导致了作者和读者之间的不信任,认为OA出版没有经过同行评审或质量很低。总之,在开放获取期刊上发表论文有利有弊。随着印度政府雄心勃勃的“一国一订阅”政策正在酝酿之中,印度的医学研究人员希望,在不久的将来,所有人都能免费获取和发表科学期刊。
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引用次数: 0
COVID-19 in people living with HIV – A case series COVID-19感染艾滋病毒感染者-病例系列
Pub Date : 2022-07-28 DOI: 10.25259/ijms_492_2021
Bhavya Chadalavada, M. R. Rao, Deepak Pandharpurkar
People with chronic diseases, old age, obesity, and immunosuppression are more susceptible to infections, including COVID-19. Human immunodeficiency virus (HIV) is widely prevalent in India, yet, the number of COVID cases in people living with HIV is low. We report six cases of COVID-19 in patients with HIV who face various challenges in the intensive care unit. The severity of their COVID infection varies from patient to patient depending on their immune status and treatment with antiretroviral therapy.
患有慢性病、老年、肥胖和免疫抑制的人更容易受到感染,包括COVID-19。人类免疫缺陷病毒(HIV)在印度广泛流行,但艾滋病毒感染者的COVID病例数量很低。我们报告了6例在重症监护病房面临各种挑战的艾滋病毒患者中的COVID-19病例。患者感染COVID的严重程度因其免疫状况和抗逆转录病毒治疗而异。
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引用次数: 0
Reactivation of cytomegalovirus infection in a post-COVID patient leading to cytomegalovirus pneumonia and colitis 1例covid后患者巨细胞病毒感染再激活导致巨细胞病毒肺炎和结肠炎
Pub Date : 2022-05-11 DOI: 10.25259/ijms_29_2022
S. Sachan, Ashutosh Kumar Singh, A. Shukla
COVID-19 is a severe disease characterized by a multifactorial immunodeficient state in critically ill patients who have had no prior immunodeficiencies. Much of the mortality in COVID has been attributed to an unprecedented high number of secondary coinfections ranging from bacterial pneumonia to opportunistic infections such as invasive aspergillosis and mucormycosis. Case reports reporting reactivation of cytomegalovirus (CMV) infection are scanty. To the best of our knowledge, we describe one of the very few cases of a previously immunocompetent healthy individual who suffered from reactivation of CMV infection and involvement of invasive infection (CMV pneumonia and CMV colitis).
COVID-19是一种严重疾病,其特征是在先前没有免疫缺陷的危重患者中出现多因素免疫缺陷状态。COVID中的大部分死亡归因于继发性合并感染的数量空前之高,从细菌性肺炎到侵袭性曲霉病和毛霉病等机会性感染。报告巨细胞病毒(CMV)感染再激活的病例报告很少。据我们所知,我们描述了一个以前免疫功能正常的健康个体遭受CMV感染再激活和侵袭性感染(CMV肺炎和CMV结肠炎)的极少数病例之一。
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引用次数: 0
The effect of hemodialysis on hearing in chronic kidney disease patients – A systematic review 血液透析对慢性肾病患者听力的影响——系统综述
Pub Date : 2022-01-25 DOI: 10.25259/ijms_135_2021
K. Kumar, Aiman Danieal Bin Hishamudin, Durga Krishnan, Harvind Lingam, Jivananthini A/P Manogaran, Nurul Asyiqin Binti Yahya, A. Jeppu
Hemodialysis as a treatment modality for Stage V chronic kidney disease (CKD) has significantly decreased mortality. However, there have been several studies reporting sensorineural hearing loss (SNHL) in these patients which affects their quality of life. The role of hemodialysis in its etiology has been widely debated and the strength of available evidence has not yet been evaluated. A systematic literature review was conducted to identify a possible association of hemodialysis to hearing loss and guide in making informed decisions in the management of CKD patients. Relevant articles from PubMed, ScienceDirect, EBSCO Medline, SCOPUS, Google Scholar, and Clinical Key were identified using Preferred Reporting Items for Systematic Review and Meta-Analyses framework. Studies that were published since the inception of the database to May 2020 and written in the English language were analyzed. A total of 36 articles on hemodialysis and sudden or SNHL were retrieved. Many were observational (13 cohorts, 10 case-control, seven case series, and six cross-sectional) studies involving 99,020 participants with ages ranging from 1 to 80 years. This review elucidates the occurrence of SNHL in CKD patients on hemodialysis. Yet, the available literature fails to provide conclusive evidence on hemodialysis as a causative agent for SNHL. Audiological assessment of all CKD patients before hemodialysis and regular follow-up may help in early diagnosis and better management of hearing loss.
血液透析作为V期慢性肾脏疾病(CKD)的一种治疗方式显著降低了死亡率。然而,有几项研究报道了这些患者的感觉神经性听力损失(SNHL),影响了他们的生活质量。血液透析在其病因中的作用一直存在广泛的争论,现有证据的强度尚未得到评估。我们进行了一项系统的文献综述,以确定血液透析与听力损失的可能关联,并指导在CKD患者管理中做出明智的决策。使用系统评价和荟萃分析框架的首选报告项目对来自PubMed、ScienceDirect、EBSCO Medline、SCOPUS、Google Scholar和Clinical Key的相关文章进行识别。分析了自数据库建立以来至2020年5月发表的以英语撰写的研究报告。共检索到36篇关于血液透析和突发或SNHL的文章。许多是观察性研究(13个队列,10个病例对照,7个病例系列和6个横断面),涉及99,020名参与者,年龄从1岁到80岁不等。本文综述了CKD血液透析患者SNHL的发生情况。然而,现有文献未能提供血液透析作为SNHL病原体的确凿证据。所有CKD患者血液透析前的听力学评估和定期随访可能有助于早期诊断和更好地管理听力损失。
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引用次数: 0
Recommendations by experts fail to impress 专家的建议并没有给人留下深刻的印象
Pub Date : 2021-12-23 DOI: 10.25259/ijms_316_2021
V. Gumaste
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引用次数: 0
Omicron in Delta dominant India: Implications and outcome 欧米克隆在三角洲占主导地位的印度:影响和结果
Pub Date : 2021-12-23 DOI: 10.25259/ijms_561_2021
Shashank V. Joshi
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引用次数: 1
Fat graft myringoplasty: A clinical study and review of literature 脂肪移植鼓膜成形术:临床研究及文献回顾
Pub Date : 2021-12-23 DOI: 10.25259/ijms_174_2021
R. Mahajan, N. Mahajan, Bavneet Kour
There are numerous surgical techniques that have been demonstrated and utilized to repair small perforations in the tympanic membrane (TM) with various graft materials such as veins, perichondrium, periosteum, and others. In our study, fat was taken as the graft material and the main aim of the study was to evaluate the success rate of graft uptake, assessment of hearing improvement, and complications of the operative procedure.In this single-center study, 46 patients underwent fat myringoplasty, 52 ears were operated from October 2016 to September 2017 for a period of 1 year. A detailed history, general physical, and a through ear, nose, and throat examination were done. Audiometric assessment was done using pure tone audiometry. Patients between the age group of 15 and 50 years were included in the study.A total of 46 patients were included in the study who met the inclusion criteria. Six patients had bilateral perforations and 40 patients had unilateral perforation, a total of 52 perforations were operated. Forty-three (82.69%) patients had successful graft uptake and graft failure was seen in 9 (17.30%) patients. Maximum gain in hearing was seen in in patients with hearing loss between 20 and 30 dB, that is, 24 patients (46.1%).Fat myringoplasty is a methodized, precise, inexpensive, mini-invasive, and cosmetic outpatient procedure for small perforations of TM. It can be done under local anesthesia and has a good success rate if the patient selection is done appropriately.
有许多外科技术已经被证明并用于修复鼓膜(TM)上的小穿孔,使用各种移植材料,如静脉、软骨膜、骨膜等。在我们的研究中,脂肪作为移植材料,研究的主要目的是评估移植的成功率,评估听力的改善,以及手术的并发症。在这项单中心研究中,2016年10月至2017年9月,46名患者接受了脂肪鼓膜成形术,52只耳手术,为期1年。详细病史,一般体格检查,耳鼻喉检查。听力评估采用纯音测听法。年龄在15岁到50岁之间的患者被纳入研究。本研究共纳入46例符合纳入标准的患者。双侧穿孔6例,单侧穿孔40例,共手术穿孔52例。43例(82.69%)患者移植成功,9例(17.30%)患者移植失败。听力损失在20 ~ 30 dB的患者中听力增益最大,即24例(46.1%)。脂肪鼓膜成形术是一种系统化的、精确的、廉价的、微创的、美容的门诊部手术,用于治疗TM的小穿孔。如果病人选择得当,可在局部麻醉下进行,成功率高。
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引用次数: 0
Kikuchi disease: An unusual cause of cervical lymphadenopathy in a young female 菊池病:年轻女性颈部淋巴结病的一种罕见病因
Pub Date : 2021-12-23 DOI: 10.25259/ijms_386_2021
Vidyulata Madhu, R. Sreedharan, V. Vinukumar
Kikuchi-Fujimoto disease (KD), also known as histiocytic necrotizing lymphadenitis, is a rare cause of unilateral cervical lymphadenopathy usually described in adolescents and young adults with female preponderance. Clinically patients present with palpable lymphadenopathy, fever, and loss of weight. Hence, it should be differentiated from other causes of lymphadenopathy such as tuberculosis, lymphoma, or malignancy. Although the majority resolve spontaneously without treatment some may require non-steroidal anti-inflammatory drug or steroids. It may also be associated with systemic lupus erythematosus. Hence early detection, prompt diagnosis, and follow-up of the patient are essential in all cases of unilateral cervical lymphadenopathy in young adults. Here, we describe a 22-year old female who presented with unilateral neck swelling and was clinically diagnosed initially as a case of tuberculous lymphadenitis which on biopsy turned out to be KD.
Kikuchi-Fujimoto病(KD),也被称为组织细胞坏死性淋巴结炎,是一种罕见的单侧颈部淋巴结病,通常发生在青少年和年轻成人中,以女性为主。临床表现为可触及的淋巴结病、发热和体重减轻。因此,它应与其他原因的淋巴结病如结核、淋巴瘤或恶性肿瘤区分开来。虽然大多数不需治疗自行消退,但有些可能需要非甾体抗炎药或类固醇。它也可能与系统性红斑狼疮有关。因此,早期发现,及时诊断,并随访患者是必要的,在所有情况下单侧颈淋巴肿大的年轻人。在这里,我们描述了一位22岁的女性,她表现为单侧颈部肿胀,最初被临床诊断为结核性淋巴结炎,活检结果为KD。
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引用次数: 0
A complicated case of delayed onset intermediate syndrome post organophosphorus poisoning: A rare case report 有机磷中毒后并发迟发性中间综合征1例:罕见病例报告
Pub Date : 2021-12-23 DOI: 10.25259/ijms_218_2021
Navtej Singh, Tarun Arora, Ankit Chamoli
Herein, we present a case of 44-year-old male who landed in our emergency department with altered mental status with difficulty in breathing after 14 days of consumption of chlorpyrifos. Organophosphorus (OP) poisoning is one of the most common causes of poisoning encountered in rural India. There are reported cases of its acute and sub-acute atypical presentation but very few of delayed onset intermediate syndrome. By means of this case report, we want to emphasize on the delayed complications post OP poisoning and importance of treating physician’s awareness to recognize and treat such complications.
在此,我们报告一例44岁男性患者,在服用毒死蜱14天后,因精神状态改变和呼吸困难而来到我们的急诊科。有机磷(OP)中毒是印度农村最常见的中毒原因之一。有急性和亚急性非典型表现的病例报道,但很少有迟发性中间综合征。通过本病例报告,我们想强调OP中毒后的延迟并发症,以及治疗医师认识和治疗此类并发症的重要性。
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引用次数: 1
Efficacy of screening cancer patients at hospital entrance for COVID-19 with a questionnaire and thermal scanning: An audit 问卷和热扫描在医院入口处筛查癌症患者COVID-19的效果:审计
Pub Date : 2021-12-17 DOI: 10.25259/ijms_193_2021
G. Mishra, N. Goel, Sudeep Gupta, S. Laskar, Apoorva V. Tiloda, Ankita A. Bhagwat, V. Kulkarni, H. Shaikh, C. Pramesh, S. Tandon, Sandeep S. Sawakare, M. Sengar, S. Biswas, S. Epari, O. Shetty, S. Desai, R. Badwe
Although commonly practiced, the accuracy, effectiveness, and safety of screening patients for COVID-19 at hospital entrances is not well documented.We performed a retrospective analysis of single institution data involving screening patients for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at hospital entrances by trained health personnel, with thermal scanning and administration of a standard questionnaire eliciting risk factors and symptoms of COVID-19. SARS-CoV-2 positivity among patients screened positive and negative and among personnel involved in screening were estimated.Between May 22, 2020, and July 4, 2020, a total of 20152 patients involving 54955 hospital visits were screened at hospital entrances of whom 668 (3.31%, 95% CI 3.07–3.57) were screened positive for suspected COVID-19 and 19484 (96.69%, 95% CI 96.44–96.93) were screened negative. Among patients screened positive, of the 638 patients with available records, 109 (17.08%, 95% CI 14.24–20.23) were confirmed to be SARS-CoV-2 positive by polymerase chain reaction test, 288 (45.14%, 95% CI 41.23–49.10) were negative, 71 (11.13%, 95% CI 8.79–13.83) were not tested after secondary assessment, and 170 (26.65%, 95% CI 23.25–30.26) patients declined the test. Among screen negative patients, 162 (0.83%, 95% CI 0.71–0.97) were SARS-CoV-2 positive. Of the 104 personnel involved in screening, 03 (2.88%, 95% CI 0.60–8.20) were confirmed to be SARS-CoV-2 positive during study period.Screening patients with a combination of thermal scanning and a standard questionnaire for COVID-19 has a high positive predictive value for detecting this infection with low risk of SARS-COV-2 transmission to the involved health personnel.
尽管这种做法很普遍,但在医院入口处对患者进行COVID-19筛查的准确性、有效性和安全性并没有得到很好的记录。我们对单个机构的数据进行了回顾性分析,这些数据涉及由训练有素的卫生人员在医院入口处筛查严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)感染患者,并使用热扫描和标准问卷调查,以了解COVID-19的危险因素和症状。估计筛查阳性和阴性患者以及参与筛查人员的SARS-CoV-2阳性情况。2020年5月22日至7月4日期间,在医院入口处共筛查了20152例患者,涉及54955次就诊,其中668例(3.31%,95% CI 3.07-3.57)为疑似COVID-19阳性,19484例(96.69%,95% CI 96.44-96.93)为阴性。在筛查阳性的638例有记录的患者中,聚合酶链反应试验确诊SARS-CoV-2阳性109例(17.08%,95% CI 14.24 ~ 20.23),阴性288例(45.14%,95% CI 41.23 ~ 49.10),二次评估后未检测71例(11.13%,95% CI 8.79 ~ 13.83),拒绝检测170例(26.65%,95% CI 23.25 ~ 30.26)。在筛查阴性患者中,162例(0.83%,95% CI 0.71-0.97)为SARS-CoV-2阳性。在参与筛查的104名人员中,有03人(2.88%,95% CI 0.60-8.20)在研究期间被确认为SARS-CoV-2阳性。结合热扫描和标准问卷筛查患者COVID-19,对相关卫生人员发现这种低风险的SARS-COV-2感染具有较高的阳性预测价值。
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引用次数: 0
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Indian journal of medical sciences
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