Breastfeeding is widely acknowledged as the preferred and recommended mode of infant nutrition. However, women who have undergone cesarean deliveries may face an increased risk of inadequate breast milk production, which can be addressed through various techniques, including the use of galactagogues, which stimulate breast milk production. Galactagogues are synthetic or plant molecules that induce, maintain, and increase milk production.In this current real-world evidence study, 53 lactating women were enrolled. During the study, they received lactobites bar for 28 days. The intestinal health of the baby, incidences of formula feeding, the volume of breast milk, baby's anthropometric measures: such as changes in height, changes in the quality of hair and skin of the mother were evaluated. The feeling of wellness in the mother and haemoglobin levels were also assessed during the study.The haemoglobin levels were significantly increased in mothers who were given lactobites bar. A significant increase was observed in hours of night and day sleep, stool frequency per day, vol. of breast milk [baseline vs 28 day: 30.19 ± 34.4 vs 448.06 ± 651.11; P<0.05], no. of diapers per day, height [baseline vs 28th day: 47.39±1.72 vs 50.1±1.62; P<0.05], changes in quality of hair and skin of mother, and the feeling of wellness in mother [baseline vs 28th day: 0.04 ± 0.19 vs 1.88 ± 0.32; P<0.05]. A significant reduction was observed in formula feeding incidence (<0.001). No side effects were reported. Lactobites bar can be used as a galactagogue to increase the human milk volume in lactating women.
母乳喂养是公认的首选和推荐的婴儿营养方式。然而，剖宫产妇女可能会面临母乳分泌不足的风险，这可以通过各种技术来解决，包括使用刺激母乳分泌的促乳剂。在目前这项真实世界证据研究中，有 53 名哺乳期妇女参加了研究。在这项研究中，53 名哺乳期妇女参加了研究。在研究期间，她们接受了为期 28 天的乳糖棒治疗。对婴儿的肠道健康、配方奶粉喂养的发生率、母乳量、婴儿的人体测量指标（如身高变化）、母亲头发和皮肤质量的变化进行了评估。在研究期间，还对母亲的健康感和血红蛋白水平进行了评估。日夜睡眠时间、每天大便次数、母乳量[基线与 28 天：30.19 ± 34.4 vs 448.06 ± 651.11；P<0.05]、每天尿布数量、身高[基线与 28 天：30.19 ± 34.4 vs 448.06 ± 651.11；P<0.05]、血红蛋白水平[基线与 28 天：30.19 ± 34.4 vs 448.06 ± 651.11；P<0.05]]均明显增加。身高[基线与第 28 天：47.39±1.72 vs 50.1±1.62；P<0.05]、母亲头发和皮肤质量的变化以及母亲的健康感[基线与第 28 天：0.04±0.19 vs 1.88±0.32；P<0.05]。配方奶喂养的发生率明显降低（<0.001）。没有副作用的报告。乳糖棒可作为催乳剂用于增加哺乳期妇女的母乳量。
{"title":"A study to evaluate the effect of Lactobites bar as a galactagogue to increase the production of milk in lactating women and promote overall healthy recovery of lactating mothers","authors":"Anish Desai, Narendra Malhotra, Neharika Malhotra, Nikhil Datar","doi":"10.18231/j.ijogr.2024.002","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.002","url":null,"abstract":"Breastfeeding is widely acknowledged as the preferred and recommended mode of infant nutrition. However, women who have undergone cesarean deliveries may face an increased risk of inadequate breast milk production, which can be addressed through various techniques, including the use of galactagogues, which stimulate breast milk production. Galactagogues are synthetic or plant molecules that induce, maintain, and increase milk production.In this current real-world evidence study, 53 lactating women were enrolled. During the study, they received lactobites bar for 28 days. The intestinal health of the baby, incidences of formula feeding, the volume of breast milk, baby's anthropometric measures: such as changes in height, changes in the quality of hair and skin of the mother were evaluated. The feeling of wellness in the mother and haemoglobin levels were also assessed during the study.The haemoglobin levels were significantly increased in mothers who were given lactobites bar. A significant increase was observed in hours of night and day sleep, stool frequency per day, vol. of breast milk [baseline vs 28 day: 30.19 ± 34.4 vs 448.06 ± 651.11; P<0.05], no. of diapers per day, height [baseline vs 28th day: 47.39±1.72 vs 50.1±1.62; P<0.05], changes in quality of hair and skin of mother, and the feeling of wellness in mother [baseline vs 28th day: 0.04 ± 0.19 vs 1.88 ± 0.32; P<0.05]. A significant reduction was observed in formula feeding incidence (<0.001). No side effects were reported. Lactobites bar can be used as a galactagogue to increase the human milk volume in lactating women.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.026
Manish R Pandya, Kishan S Adroja, Vaishvi C Patel
Key to a successful outcome in a rare life threatening condition like cesarean scar ectopic pregnancy is early diagnosis and treatment. The risk of massive haemorrhage can lead inevitably to a hysterectomy in past. The most effective method of treatment is not yet found. We report a case of a previous LCSC and one D& E of 35-year-old female (G3P1A1L1) with 7 weeks of amenorrhea and vaginal bleeding. A gestational sac with an embryo in the cesarean scar canal was seen on ultrasonography. The fertility-sparing therapeutic strategy involved cesarean scar curettage to remove the trophoblastic under ultrasound.
{"title":"A skillful approach in a case of caesarean scar ectopic pregnancy","authors":"Manish R Pandya, Kishan S Adroja, Vaishvi C Patel","doi":"10.18231/j.ijogr.2024.026","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.026","url":null,"abstract":"Key to a successful outcome in a rare life threatening condition like cesarean scar ectopic pregnancy is early diagnosis and treatment. The risk of massive haemorrhage can lead inevitably to a hysterectomy in past. The most effective method of treatment is not yet found. We report a case of a previous LCSC and one D& E of 35-year-old female (G3P1A1L1) with 7 weeks of amenorrhea and vaginal bleeding. A gestational sac with an embryo in the cesarean scar canal was seen on ultrasonography. The fertility-sparing therapeutic strategy involved cesarean scar curettage to remove the trophoblastic under ultrasound.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"2 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.022
Saswati Mukhopadhyay
Hb Lepore is a fusion globin protein made of fused chains of delta and beta globin. It is a deletion haemoglobinopathy. In homozygote form, it is similar to transfusion dependent beta thalassaemia major, and in the heterozygous form, it causes mild microcytic hypochromic anaemia. In this case report, the couple has heterozygous Hb Lepore and heterozygous beta thalassaemia, with a pregnancy of 15weeks gestation. Prenatal testing by amniocentesis and HBB gene analysis for the fetus was done by sequencing and MLPA to detect the different types of mutations present in the parents. This case report reveals the importance of MLPA to be done along with sanger sequencing, to detect all types of mutations in the HBB gene.
{"title":"Haemoglobin lepore and beta thalassaemia traits – Prenatal testing by both sequence analysis and MLPA for HBB gene: A case report","authors":"Saswati Mukhopadhyay","doi":"10.18231/j.ijogr.2024.022","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.022","url":null,"abstract":"Hb Lepore is a fusion globin protein made of fused chains of delta and beta globin. It is a deletion haemoglobinopathy. In homozygote form, it is similar to transfusion dependent beta thalassaemia major, and in the heterozygous form, it causes mild microcytic hypochromic anaemia. In this case report, the couple has heterozygous Hb Lepore and heterozygous beta thalassaemia, with a pregnancy of 15weeks gestation. Prenatal testing by amniocentesis and HBB gene analysis for the fetus was done by sequencing and MLPA to detect the different types of mutations present in the parents. This case report reveals the importance of MLPA to be done along with sanger sequencing, to detect all types of mutations in the HBB gene.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pregnancy is an immune-compromised state and pregnancy affected with COVID-19 infection is at a higher risk of adverse perinatal results. Data on feto-maternal outcomes in pregnancies infected with COVID-19 is sparse, which makes it difficult to draw conclusions on vertical transmission.To study the perinatal outcomes of covid-19 affected pregnant women.A prospective observational study was conducted over eighteen months, on 320 COVID-19 positive antenatal patients. Clinical manifestations of pregnancies with COVID-19, demographic profile, pregnancy outcomes were recorded. Important laboratory parameters were assessed along with COVID-19 inflammatory markers like serum ferritin,D-Dimer, CRP etc. Neonatal outcomes assessed included APGAR score, fetal deaths, birth weight, NICU admissions. Neonatal infections were screened by testing for SARS-CoV-2 positivity in neonatal throat swab samples.61.5% of patients complained of pain abdomen, followed by bleeding PV in 1.9%. 52.19% of the patients were asymptomatic for COVID-19 symptoms, followed by fever in 34.69%. Most common risk factor associated was hypothyroidism. Anemia was found in 22%, coagulation parameters were elevated in 30% and COVID-19 inflammatory markers were raised in more than 90% cases. Maternal and neonatal ICU admission rates were 4.69% and 30.34% respectively. Neonatal infection rate was 3.1%.COVID-19 was mainly seen in primigravida, without affecting the birth weight of babies. Coagulation profile and renal parameters were deranged in 30 percent of the patients, without any life any threatening complications. COVID-19 specific inflammatory markers showed derangement in more than 90% cases, although majority of them were asymptomatic. The rate of COVID-19 positivity among newborns was 3.1%.
{"title":"Perinatal outcomes of COVID-19 affected pregnant women in a tertiary care center of eastern India","authors":"Sujata Pendyala, Shiwangi Kumari, Tanushree Sandipta Rath, Chandrabhanu Dalal, Dattatreya Kar, Sujata Priyadarshini Mishra","doi":"10.18231/j.ijogr.2024.014","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.014","url":null,"abstract":"Pregnancy is an immune-compromised state and pregnancy affected with COVID-19 infection is at a higher risk of adverse perinatal results. Data on feto-maternal outcomes in pregnancies infected with COVID-19 is sparse, which makes it difficult to draw conclusions on vertical transmission.To study the perinatal outcomes of covid-19 affected pregnant women.A prospective observational study was conducted over eighteen months, on 320 COVID-19 positive antenatal patients. Clinical manifestations of pregnancies with COVID-19, demographic profile, pregnancy outcomes were recorded. Important laboratory parameters were assessed along with COVID-19 inflammatory markers like serum ferritin,D-Dimer, CRP etc. Neonatal outcomes assessed included APGAR score, fetal deaths, birth weight, NICU admissions. Neonatal infections were screened by testing for SARS-CoV-2 positivity in neonatal throat swab samples.61.5% of patients complained of pain abdomen, followed by bleeding PV in 1.9%. 52.19% of the patients were asymptomatic for COVID-19 symptoms, followed by fever in 34.69%. Most common risk factor associated was hypothyroidism. Anemia was found in 22%, coagulation parameters were elevated in 30% and COVID-19 inflammatory markers were raised in more than 90% cases. Maternal and neonatal ICU admission rates were 4.69% and 30.34% respectively. Neonatal infection rate was 3.1%.COVID-19 was mainly seen in primigravida, without affecting the birth weight of babies. Coagulation profile and renal parameters were deranged in 30 percent of the patients, without any life any threatening complications. COVID-19 specific inflammatory markers showed derangement in more than 90% cases, although majority of them were asymptomatic. The rate of COVID-19 positivity among newborns was 3.1%.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"5 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.008
K. Nayar, Prabhsimran Singh, T. Kiruthiga
: This study aims to develop a semi-quantitative Food Frequency Questionnaire (FFQ) to assess vitamin A levels using 24-hour food recall in pregnant women and further validate the formulated FFQ. Our study found a significant correlation between the 24-hour recall and FFQ results, indicating that the developed FFQ is a valid and useful tool for assessing vitamin A intake in pregnant women.: This was a two-phase study conducted at a Tertiary health care centre in Chennai, Tamil Nadu, consisting of two groups: Group A (55 participants) and Group B (68 participants). Phase I consisted of administering a 24-hour food recall to group A participants to collect their vitamin A intake and develop a FFQ. During Phase II of the study, FFQ was administered to Group B participants, which estimated vitamin A intake over the past 30 days. These patients were then contacted within a week of the administration of FFQ, and a 24-hour recall was administered. The results collected from the 24-hour recall were used to validate FFQ.: Results showed r value under Pearson coefficient was 0.743 (95% CI = 0.613 - 0.834, p <0.001), indicating a strong and significant relationship, and rho under Spearman coefficient was 0.686 (95% CI = 0.535 - 0.794, p <0.001) indicated the presence of a significant correlation suggesting the FFQ is valid.: The results of this study found that the developed FFQ is a valid and useful tool for assessing vitamin A intake in pregnant women and can be utilised to assess vitamin A intake.
:本研究旨在开发一种半定量食物频率问卷（FFQ），利用 24 小时食物回忆来评估孕妇的维生素 A 水平，并进一步验证所制定的 FFQ。我们的研究发现，24 小时食物回忆与 FFQ 结果之间存在明显的相关性，这表明所开发的 FFQ 是评估孕妇维生素 A 摄入量的有效且有用的工具。 这是一项在泰米尔纳德邦钦奈市一家三级医疗保健中心开展的分两个阶段进行的研究，包括两组：A 组（55 人）和 B 组（68 人）。第一阶段包括对 A 组参与者进行 24 小时食物回忆，以收集他们的维生素 A 摄入量并编制 FFQ。在研究的第二阶段，对 B 组参与者进行了 FFQ 调查，以估计过去 30 天的维生素 A 摄入量。然后，在发放 FFQ 后一周内与这些患者取得联系，并进行 24 小时回忆。结果显示，Pearson 系数下的 r 值为 0.743（95% CI = 0.613 - 0.834，p <0.001），表明两者关系密切且显著；Spearman 系数下的 rho 值为 0.686（95% CI = 0.535 - 0.794，p <0.001），表明两者关系密切且显著。本研究结果表明，开发的 FFQ 是评估孕妇维生素 A 摄入量的有效和有用的工具，可用于评估维生素 A 摄入量。
{"title":"Assessing vitamin A intake among pregnant women: The creation and validation of a semi-quantitative FFQ specific for vitamin A in a tertiary healthcare center","authors":"K. Nayar, Prabhsimran Singh, T. Kiruthiga","doi":"10.18231/j.ijogr.2024.008","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.008","url":null,"abstract":": This study aims to develop a semi-quantitative Food Frequency Questionnaire (FFQ) to assess vitamin A levels using 24-hour food recall in pregnant women and further validate the formulated FFQ. Our study found a significant correlation between the 24-hour recall and FFQ results, indicating that the developed FFQ is a valid and useful tool for assessing vitamin A intake in pregnant women.: This was a two-phase study conducted at a Tertiary health care centre in Chennai, Tamil Nadu, consisting of two groups: Group A (55 participants) and Group B (68 participants). Phase I consisted of administering a 24-hour food recall to group A participants to collect their vitamin A intake and develop a FFQ. During Phase II of the study, FFQ was administered to Group B participants, which estimated vitamin A intake over the past 30 days. These patients were then contacted within a week of the administration of FFQ, and a 24-hour recall was administered. The results collected from the 24-hour recall were used to validate FFQ.: Results showed r value under Pearson coefficient was 0.743 (95% CI = 0.613 - 0.834, p <0.001), indicating a strong and significant relationship, and rho under Spearman coefficient was 0.686 (95% CI = 0.535 - 0.794, p <0.001) indicated the presence of a significant correlation suggesting the FFQ is valid.: The results of this study found that the developed FFQ is a valid and useful tool for assessing vitamin A intake in pregnant women and can be utilised to assess vitamin A intake.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"21 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The diagnosis of placenta accreta spectrum (PAS) in pregnancy is associated with severe maternal complications and is potentially life threatening. Moreover, PAS is difficult to diagnose in the first trimester, and the accuracy is low. A prenatal diagnosis is pivotal for planning an optimal management in PAS. A first trimester US(Ultrasound) can detect PAS in good proportion of cases, although the sensitivity is lower than a second or third trimester US. An early first trimester US can further help predict severity of PAS and its surgical outcome. As the management and diagnosis remains a challenge as far as PAS in early pregnancy is concerned, a high clinical suspicion especially in cases of previous uterine scar and bleeding following a surgical evacuation cannot be overemphasised. We report a case of Placenta Percreta in First Trimester, its rarity and diagnostic dilemma.
妊娠期胎盘早剥谱（PAS）的诊断与严重的孕产妇并发症有关，并可能危及生命。此外，PAS 在妊娠头三个月很难诊断，准确率也很低。产前诊断对于制定最佳治疗方案至关重要。虽然敏感性低于第二或第三孕期的 US，但第一孕期的 US（超声波）可以检测出相当一部分的 PAS 病例。妊娠头三个月的早期超声检查可进一步帮助预测 PAS 的严重程度及其手术结果。就孕早期胎盘早剥而言，管理和诊断仍是一项挑战，因此临床上必须高度怀疑，尤其是在既往有子宫疤痕和手术排空后出血的病例中，这一点无论如何强调都不为过。我们报告了一例孕早期前置胎盘及其罕见性和诊断难题。
{"title":"Placenta percreta in first trimester – A rarity and diagnostic dilemma","authors":"Bhavika Kalthe, Tejinder Kaur, Anshu Mujalda, Reena Bisht, Pinakin Kaushik","doi":"10.18231/j.ijogr.2024.021","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.021","url":null,"abstract":"The diagnosis of placenta accreta spectrum (PAS) in pregnancy is associated with severe maternal complications and is potentially life threatening. Moreover, PAS is difficult to diagnose in the first trimester, and the accuracy is low. A prenatal diagnosis is pivotal for planning an optimal management in PAS. A first trimester US(Ultrasound) can detect PAS in good proportion of cases, although the sensitivity is lower than a second or third trimester US. An early first trimester US can further help predict severity of PAS and its surgical outcome. As the management and diagnosis remains a challenge as far as PAS in early pregnancy is concerned, a high clinical suspicion especially in cases of previous uterine scar and bleeding following a surgical evacuation cannot be overemphasised. We report a case of Placenta Percreta in First Trimester, its rarity and diagnostic dilemma.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"23 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.023
Astha Chetan Saravia, Suman Gupta, Kumari Tripti
WHO in a publication about neurological disorders states, “adequate pain treatment is a human right and it is the duty of every health care system to provide it.” Pregnancy being a hyperestrogenic state, is a predisposing factor, for Trigeminal Neuralgia. Trigeminal neuralgia is a debilitating condition that causes serious morbidity to the patient, thus hampering the daily activities of a patient. Thus, it becomes imperative to effectively manage and treat patients with trigeminal neuralgia. Various treatment regimens are being practised to manage trigeminal neuralgia. Carbamazepine is the drug of choice but being teratogenic, it can not be used during pregnancy. Radiofrequency ablation is another treatment modality for treatment of trigeminal neuralgia which is safer compared to the medical management.
{"title":"Management of a case of trigeminal neuralgia in pregnancy with radiofrequency ablation of the nerve","authors":"Astha Chetan Saravia, Suman Gupta, Kumari Tripti","doi":"10.18231/j.ijogr.2024.023","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.023","url":null,"abstract":"WHO in a publication about neurological disorders states, “adequate pain treatment is a human right and it is the duty of every health care system to provide it.” Pregnancy being a hyperestrogenic state, is a predisposing factor, for Trigeminal Neuralgia. Trigeminal neuralgia is a debilitating condition that causes serious morbidity to the patient, thus hampering the daily activities of a patient. Thus, it becomes imperative to effectively manage and treat patients with trigeminal neuralgia. Various treatment regimens are being practised to manage trigeminal neuralgia. Carbamazepine is the drug of choice but being teratogenic, it can not be used during pregnancy. Radiofrequency ablation is another treatment modality for treatment of trigeminal neuralgia which is safer compared to the medical management.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"26 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: Anemia is a common health issue during pregnancy, with various factors influencing its occurrence. Iron deficiency often leads to iron deficiency anemia (IDA), significantly impacting maternal and fetal health.: This study aims to investigate the complete blood count and nutritional status, including serum iron profile, vitamin B12, and folate levels in antenatal patients. : The study involved 160 participants, predominantly from rural areas. The severity of anemia among the participants was classified according to WHO guidelines.: Iron deficiency was observed in 33.75% of women, folate deficiency in 20%, and vitamin B12 deficiency in 11.25%. Some women exhibited a combination of deficiencies. The average hemoglobin level was found to be 8.69 g/dL, and the mean iron level was 35.95 µg/dL. The average ferritin levels were observed to be 49.65 ng/mL. Lastly, the Vitamin B12 and folate levels averaged at 130.21 pg/mL and 14.76 ng/mL respectively.: These findings provide valuable insights into the nutritional status of pregnant women and highlight the need for targeted interventions to address micronutrient deficiencies during pregnancy.
{"title":"Anemia profiling in antenatal women at a tertiary care center in northern India: An observational study","authors":"Rupita Kulshrestha, Shivani Singh, Vandana Tiwari, Vibhav Nigam, Manish Raj Kulshrestha","doi":"10.18231/j.ijogr.2024.010","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.010","url":null,"abstract":": Anemia is a common health issue during pregnancy, with various factors influencing its occurrence. Iron deficiency often leads to iron deficiency anemia (IDA), significantly impacting maternal and fetal health.: This study aims to investigate the complete blood count and nutritional status, including serum iron profile, vitamin B12, and folate levels in antenatal patients. : The study involved 160 participants, predominantly from rural areas. The severity of anemia among the participants was classified according to WHO guidelines.: Iron deficiency was observed in 33.75% of women, folate deficiency in 20%, and vitamin B12 deficiency in 11.25%. Some women exhibited a combination of deficiencies. The average hemoglobin level was found to be 8.69 g/dL, and the mean iron level was 35.95 µg/dL. The average ferritin levels were observed to be 49.65 ng/mL. Lastly, the Vitamin B12 and folate levels averaged at 130.21 pg/mL and 14.76 ng/mL respectively.: These findings provide valuable insights into the nutritional status of pregnant women and highlight the need for targeted interventions to address micronutrient deficiencies during pregnancy.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"17 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.016
S. Elamurugan, Hemavathy Vijayakumar, Himabindu Nagulapally
Ectopic pregnancy accounts for 1 to 2% of all conception. Ectopic pregnancy in the cornua (part from where fallopian tube exit the endometrial cavity) is rare and its management is tricky. We present a case of cornual ectopic pregnancy complicated by fibroid uterus for which hysterectomy was done.
{"title":"Ectopic pregnancy – A conundrum","authors":"S. Elamurugan, Hemavathy Vijayakumar, Himabindu Nagulapally","doi":"10.18231/j.ijogr.2024.016","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.016","url":null,"abstract":"Ectopic pregnancy accounts for 1 to 2% of all conception. Ectopic pregnancy in the cornua (part from where fallopian tube exit the endometrial cavity) is rare and its management is tricky. We present a case of cornual ectopic pregnancy complicated by fibroid uterus for which hysterectomy was done.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"21 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.004
J. Alegbeleye, Celestine Osita John
Cancer antigen 125 (Ca-125) is currently used as an adjunct to ovarian cancer diagnosis, prognosis, and monitoring. Platelet (PLT) count and Ca-125 levels are both prognostic markers in ovarian cancer that are linked to inflammation and immune evasion.To determine the relationship between pre-operative platelet count and serum Ca-125 level, and their diagnostic accuracy for the prediction of stage IV epithelial ovarian cancer.The study included forty-two women with histologic diagnosis of epithelial ovarian cancer managed at the University of Port Harcourt Teaching Hospital between January 1, 2016, and December 31, 2020. Following informed consent, a data collection form was used to obtain socio-demographic and clinical characteristics. Pretreatment levels of Cancer Antigen 125 (Ca-125) and Platelets count (PLT) were determined from blood samples. The Spearman correlation coefficient was used to determine the relationship between PLT and Ca-125, and the Receiver Operating Characteristic (ROC) curve analysis was used to assess the predictive accuracy of PLT count alone and PLT-Ca-125. The sample median platelet count was 308 (307) x 10/L and median Ca-125 was 286µ/ml (397). Pre-operative platelets count was significantly associated with Ca-125 (rho= 0.28 p-value = 0.03). Ca-125 had a statistically significant relationship with ovarian cancer histology (X2:19.522; p-value 0.001). PLT-Ca-125 (0.51) and PLT only (0.29) had a statistically significant positive correlation with ovarian cancer stage (p 0.001). Since it had an area under the curve (AUC) greater than 0.7, PLT-Ca-125 can be used as a predictive model to correctly stage patients with epithelial ovarian cancer. Ca-125 level (z:-2.24; p-value = 0.025) was significantly associated with thrombocytosis in ovarian cancer patients.Platelet count and Ca-125 levels do correlate in blood samples taken from ovarian cancer patients prior to treatment. Furthermore, PLT-Ca-125 levels could be used to predict advanced stage disease.
{"title":"Correlation between pre-operative platelets count and serum cancer antigen-125 level in epithelial ovarian carcer","authors":"J. Alegbeleye, Celestine Osita John","doi":"10.18231/j.ijogr.2024.004","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.004","url":null,"abstract":"Cancer antigen 125 (Ca-125) is currently used as an adjunct to ovarian cancer diagnosis, prognosis, and monitoring. Platelet (PLT) count and Ca-125 levels are both prognostic markers in ovarian cancer that are linked to inflammation and immune evasion.To determine the relationship between pre-operative platelet count and serum Ca-125 level, and their diagnostic accuracy for the prediction of stage IV epithelial ovarian cancer.The study included forty-two women with histologic diagnosis of epithelial ovarian cancer managed at the University of Port Harcourt Teaching Hospital between January 1, 2016, and December 31, 2020. Following informed consent, a data collection form was used to obtain socio-demographic and clinical characteristics. Pretreatment levels of Cancer Antigen 125 (Ca-125) and Platelets count (PLT) were determined from blood samples. The Spearman correlation coefficient was used to determine the relationship between PLT and Ca-125, and the Receiver Operating Characteristic (ROC) curve analysis was used to assess the predictive accuracy of PLT count alone and PLT-Ca-125. The sample median platelet count was 308 (307) x 10/L and median Ca-125 was 286µ/ml (397). Pre-operative platelets count was significantly associated with Ca-125 (rho= 0.28 p-value = 0.03). Ca-125 had a statistically significant relationship with ovarian cancer histology (X2:19.522; p-value 0.001). PLT-Ca-125 (0.51) and PLT only (0.29) had a statistically significant positive correlation with ovarian cancer stage (p 0.001). Since it had an area under the curve (AUC) greater than 0.7, PLT-Ca-125 can be used as a predictive model to correctly stage patients with epithelial ovarian cancer. Ca-125 level (z:-2.24; p-value = 0.025) was significantly associated with thrombocytosis in ovarian cancer patients.Platelet count and Ca-125 levels do correlate in blood samples taken from ovarian cancer patients prior to treatment. Furthermore, PLT-Ca-125 levels could be used to predict advanced stage disease.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":"16 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：