Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.013
A. Subbian, Jeevithan Shanmugam, Uma Ram
: SARS COV-2 vaccination was a global effort to tackle the Covid-19 pandemic. During the vaccination drive, several concerns were raised about the potential adverse effects of the Covid-19 vaccines, which included the impact on menstruation and fertility in women. This study aimed to assess experiences of Indian Women with covid vaccination and its effects on their menstruation. A prospective web-based survey was conducted targeting women aged 18years and above and who had taken atleast one dose of the covid vaccine. : The total number of responses received were 363. After excluding those with missing details, 342 respondents were included in the analysis. The mean age of the participants was 38.02 ± 7.8 years. 68.1% of the respondents (233/342) reported no change in the periodicity of their cycles post vaccination and 79.5% (272/342) reported no change in the menstrual flow. Forty three women (12.6%) reported experiencing heavy flow post vaccination. In this group which experienced heavy menses, 81.5% (35/43) reported that the heavy menses was self-limiting and did not require any treatment. 9.3% (4/43) of these symptomatic women recorded that short term treatment was sought. Another 9.3% of women reported persisting menstrual changes, at the time of the survey, despite taking prescribed treatment. It was also noted that the changes in menstrual cycles were significantly more in vaccinated nulliparous women.: Covid vaccination appears to have no or little impact on menstrual cycles in two-thirds of the women taking the vaccine. 31.9% of the women in the survey reported some change in their menstrual timing or flow. Most changes were self -limiting. About 1% (4/342) may have longer standing menstrual impact, requiring treatment.
{"title":"The effect of covid vaccination on menstruation and attitude to the vaccine among Indian women – Results of a prospective survey","authors":"A. Subbian, Jeevithan Shanmugam, Uma Ram","doi":"10.18231/j.ijogr.2024.013","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.013","url":null,"abstract":": SARS COV-2 vaccination was a global effort to tackle the Covid-19 pandemic. During the vaccination drive, several concerns were raised about the potential adverse effects of the Covid-19 vaccines, which included the impact on menstruation and fertility in women. This study aimed to assess experiences of Indian Women with covid vaccination and its effects on their menstruation. A prospective web-based survey was conducted targeting women aged 18years and above and who had taken atleast one dose of the covid vaccine. : The total number of responses received were 363. After excluding those with missing details, 342 respondents were included in the analysis. The mean age of the participants was 38.02 ± 7.8 years. 68.1% of the respondents (233/342) reported no change in the periodicity of their cycles post vaccination and 79.5% (272/342) reported no change in the menstrual flow. Forty three women (12.6%) reported experiencing heavy flow post vaccination. In this group which experienced heavy menses, 81.5% (35/43) reported that the heavy menses was self-limiting and did not require any treatment. 9.3% (4/43) of these symptomatic women recorded that short term treatment was sought. Another 9.3% of women reported persisting menstrual changes, at the time of the survey, despite taking prescribed treatment. It was also noted that the changes in menstrual cycles were significantly more in vaccinated nulliparous women.: Covid vaccination appears to have no or little impact on menstrual cycles in two-thirds of the women taking the vaccine. 31.9% of the women in the survey reported some change in their menstrual timing or flow. Most changes were self -limiting. About 1% (4/342) may have longer standing menstrual impact, requiring treatment.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.020
S. Lad, Chaya Chourasia, Pavan Gulhane
We report a case of scar ectopic pregnancy which is the rarest type of all ectopic pregnancies. We need to diagnose & treat this condition in the early weeks of pregnancy to avoid the complication. This case of Caesarean scar ectopic pregnancy (CSEP) was diagnosed during an antenatal ultrasound scan, at six weeks of pregnancy. An ultrasound scan of this case revealed the gestation sac in the lower uterine segment at the previous caesarean scar.
{"title":"Transvaginal sonographic diagnosis of caesarean scar ectopic pregnancy: A case report","authors":"S. Lad, Chaya Chourasia, Pavan Gulhane","doi":"10.18231/j.ijogr.2024.020","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.020","url":null,"abstract":"We report a case of scar ectopic pregnancy which is the rarest type of all ectopic pregnancies. We need to diagnose & treat this condition in the early weeks of pregnancy to avoid the complication. This case of Caesarean scar ectopic pregnancy (CSEP) was diagnosed during an antenatal ultrasound scan, at six weeks of pregnancy. An ultrasound scan of this case revealed the gestation sac in the lower uterine segment at the previous caesarean scar.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.018
Archana Sampath
Leiomyoma, a benign solid tumour found in the female genital tract, affects 3%-13% of pregnancies. These growths occur as sub serosal, intramural, or submucosal tumours. Approximately 10%–30% of pregnant women experience fibroid-related complications, such as spontaneous abortion, preterm labour, soft tissue dystocia, uterine inertia, feto pelvic disproportion, fetal malposition, and postpartum hemorrhage and a higher risk of caesarean delivery. This case report aims to shed light on the complexities arising in the postpartum period for women previously diagnosed with large fibroids during pregnancy. By exploring a specific case, this report emphasizes the importance of understanding and addressing these complications comprehensively. A 27-year-old primigravida sought antenatal care at 8 weeks of gestation with a 6cm intramural fibroid. Her pregnancy progressed smoothly, leading to a healthy vaginal delivery. However, at 7 weeks postpartum, she experienced pelvic discomfort, heavy lochia, and bleeding. Imaging revealed a submucosal fibroid protruding into the endometrial cavity with degenerating component Myomectomy performed. This case underscores the necessity of a comprehensive understanding of complications associated with large fibroids, spanning both the antenatal and postpartum periods. Heightened awareness and timely intervention are crucial to ensuring optimal outcomes for both maternal and foetal health.
{"title":"Perilous myoma in the puerperium: A case report","authors":"Archana Sampath","doi":"10.18231/j.ijogr.2024.018","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.018","url":null,"abstract":"Leiomyoma, a benign solid tumour found in the female genital tract, affects 3%-13% of pregnancies. These growths occur as sub serosal, intramural, or submucosal tumours. Approximately 10%–30% of pregnant women experience fibroid-related complications, such as spontaneous abortion, preterm labour, soft tissue dystocia, uterine inertia, feto pelvic disproportion, fetal malposition, and postpartum hemorrhage and a higher risk of caesarean delivery. This case report aims to shed light on the complexities arising in the postpartum period for women previously diagnosed with large fibroids during pregnancy. By exploring a specific case, this report emphasizes the importance of understanding and addressing these complications comprehensively. A 27-year-old primigravida sought antenatal care at 8 weeks of gestation with a 6cm intramural fibroid. Her pregnancy progressed smoothly, leading to a healthy vaginal delivery. However, at 7 weeks postpartum, she experienced pelvic discomfort, heavy lochia, and bleeding. Imaging revealed a submucosal fibroid protruding into the endometrial cavity with degenerating component Myomectomy performed. This case underscores the necessity of a comprehensive understanding of complications associated with large fibroids, spanning both the antenatal and postpartum periods. Heightened awareness and timely intervention are crucial to ensuring optimal outcomes for both maternal and foetal health.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.030
R. K. Garg
{"title":"Nurturing a healthy future: The impact of the mothers' absolute affection (MAA) programme on infant and young child feeding","authors":"R. K. Garg","doi":"10.18231/j.ijogr.2024.030","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.030","url":null,"abstract":"","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140455995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.012
Sreelakshmy K, Shahnas M
: The body mass index (BMI) before pregnancy and gestational weight gain (GWG) may have an association with the outcome of pregnancies. Preeclampsia, gestational diabetes, macrosomia show an association with the BMI. A retrospective analysis of the data collected from 720 pregnant mothers during the period from January 2017 to January 2019 in a tertiary health care centre. The chi-square test was done to assess the categorical data.: Gestational hypertension was significant in overweight women and those who gained weight above recommended range. (22.4% Vs. 0%; p <0.001) GDM was noted in a significant percentage of pregnant women within the recommended weight gain group. (12.4% Vs. 0%; p<0.001).: Pre-pregnancy dietary counselling, physical and lifestyle modifications have a role in bringing down the incidence of GDM and gestational hypertension.
{"title":"Association of pre-pregnancy body mass index to gestational weight gain, diabetes mellitus and hypertension","authors":"Sreelakshmy K, Shahnas M","doi":"10.18231/j.ijogr.2024.012","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.012","url":null,"abstract":": The body mass index (BMI) before pregnancy and gestational weight gain (GWG) may have an association with the outcome of pregnancies. Preeclampsia, gestational diabetes, macrosomia show an association with the BMI. A retrospective analysis of the data collected from 720 pregnant mothers during the period from January 2017 to January 2019 in a tertiary health care centre. The chi-square test was done to assess the categorical data.: Gestational hypertension was significant in overweight women and those who gained weight above recommended range. (22.4% Vs. 0%; p <0.001) GDM was noted in a significant percentage of pregnant women within the recommended weight gain group. (12.4% Vs. 0%; p<0.001).: Pre-pregnancy dietary counselling, physical and lifestyle modifications have a role in bringing down the incidence of GDM and gestational hypertension.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.006
Nidhi Mimani Gupta, Hina Mittal, Neha Kachroo, Neelam Goyal
Cervical cancer stands as the second most prevalent cancer among women in the reproductive age bracket. According to Globocan 2020, there were 604,100 newly diagnosed cases of cervical cancer worldwide, resulting in 341,831 fatalities. In India, there are 436.76 million women aged 15 and older who face the risk of developing cervical cancer. To explore the basic knowledge of cervical cancer, its risk factors, and preventive measures among female healthcare professionals and medical students.A cross-sectional study among all 205 female healthcare providers comprising of doctors, medical students (1st, 2nd & 3rd-year MBBS), and nurses was conducted at Gautam Buddha Chikitsa Mahavidyalaya, Jhajhra, Dehradun, in December 2023. Google Forms platform was used to conduct the pre-composed online survey. Data was entered and analyzed with SPSS software version 26.A maximum number (141) of participants identified HPV infection as a risk factor for cervical cancer followed by multiple sexual partners (137) while 41.95% of subjects knew about early pregnancy as a risk factor for cervical cancer. Knowledge of risk factors for cervical cancer is highest among doctors followed by nurses and students. 81.95% of participants knew that cervical cancer is preventable and screening helps in the prevention of cervical cancer.Regular upgradation of knowledge of female nursing personnel is crucial since women tend to seek advice from them more often. Similarly, HPV and cervical cancer should be strategically incorporated at the beginning of the medical curriculum.
{"title":"Awareness about cervical cancer risk factors and its prevention among female healthcare professionals in north India","authors":"Nidhi Mimani Gupta, Hina Mittal, Neha Kachroo, Neelam Goyal","doi":"10.18231/j.ijogr.2024.006","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.006","url":null,"abstract":"Cervical cancer stands as the second most prevalent cancer among women in the reproductive age bracket. According to Globocan 2020, there were 604,100 newly diagnosed cases of cervical cancer worldwide, resulting in 341,831 fatalities. In India, there are 436.76 million women aged 15 and older who face the risk of developing cervical cancer. To explore the basic knowledge of cervical cancer, its risk factors, and preventive measures among female healthcare professionals and medical students.A cross-sectional study among all 205 female healthcare providers comprising of doctors, medical students (1st, 2nd & 3rd-year MBBS), and nurses was conducted at Gautam Buddha Chikitsa Mahavidyalaya, Jhajhra, Dehradun, in December 2023. Google Forms platform was used to conduct the pre-composed online survey. Data was entered and analyzed with SPSS software version 26.A maximum number (141) of participants identified HPV infection as a risk factor for cervical cancer followed by multiple sexual partners (137) while 41.95% of subjects knew about early pregnancy as a risk factor for cervical cancer. Knowledge of risk factors for cervical cancer is highest among doctors followed by nurses and students. 81.95% of participants knew that cervical cancer is preventable and screening helps in the prevention of cervical cancer.Regular upgradation of knowledge of female nursing personnel is crucial since women tend to seek advice from them more often. Similarly, HPV and cervical cancer should be strategically incorporated at the beginning of the medical curriculum.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139962667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.007
Sunil K S, Sunil C V, Apoorva Jain
: During an evaluation of infertile men when all standard semen parameters are normal, a significant proportion of infertile men are found to have increased levels of DNA damage that may adversely affect fertility. To evaluate the correlation between sperm DNA Fragmentation Index (DFI) with demographic characteristics, sexual history, social habits, chronic illness, BMI, physical characteristics, and abstinence period. The current study was carried out among male patients visiting an infertility clinic at SDM College of Medical Sciences and Hospital, Dharwad.The present has shownno statistically significant association between DFI and socio-demographic characteristics like age, married life, contraceptive usage, sexual factors, personal habits, chronic illness, BMI, and physical characteristics of semen analysis like liquefaction and viscosity of the study participants. DFI categories and semen traits including normal forms, head defects, tail defects, amorphous forms, droplet forms, and viable sperms had different means, however these differences (p=0.4378) were not statistically significant.
:在对精液所有标准参数都正常的不育男性进行评估时，发现相当一部分不育男性的 DNA 损伤程度增加，可能会对生育能力产生不利影响。目的：评估精子 DNA 碎片指数（DFI）与人口统计学特征、性史、社会习惯、慢性疾病、体重指数、身体特征和禁欲时间之间的相关性。本研究在达尔瓦德 SDM 医学院和医院不孕不育门诊就诊的男性患者中进行。研究结果表明，精子 DNA 碎片指数（DFI）与研究对象的年龄、婚姻生活、避孕药具使用情况、性因素、个人习惯、慢性疾病、体重指数等社会人口学特征以及精液分析的液化度和粘度等物理特征之间没有统计学意义上的显著关联。DFI 类别和精液特征（包括正常形态、头部缺陷、尾部缺陷、无定形形态、液滴形态和有活力精子）的平均值不同，但这些差异（P=0.4378）在统计学上并不显著。
{"title":"Correlation between sperm DNA fragmentation index (DFI) with demographic characteristics, sexual history, social habits, chronic illness, BMI: A cross-sectional study","authors":"Sunil K S, Sunil C V, Apoorva Jain","doi":"10.18231/j.ijogr.2024.007","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.007","url":null,"abstract":": During an evaluation of infertile men when all standard semen parameters are normal, a significant proportion of infertile men are found to have increased levels of DNA damage that may adversely affect fertility. To evaluate the correlation between sperm DNA Fragmentation Index (DFI) with demographic characteristics, sexual history, social habits, chronic illness, BMI, physical characteristics, and abstinence period. The current study was carried out among male patients visiting an infertility clinic at SDM College of Medical Sciences and Hospital, Dharwad.The present has shownno statistically significant association between DFI and socio-demographic characteristics like age, married life, contraceptive usage, sexual factors, personal habits, chronic illness, BMI, and physical characteristics of semen analysis like liquefaction and viscosity of the study participants. DFI categories and semen traits including normal forms, head defects, tail defects, amorphous forms, droplet forms, and viable sperms had different means, however these differences (p=0.4378) were not statistically significant.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.015
Anirudh Mehta, Saurabh Dani, Alaka Godbole
The study evaluated the efficacy and safety of colloidal nano silver gel (SilverSol Vagigel) (A patented technology from American Biotech Labs, USA) in combination with 0.2% lactic acid in the female subjects for the treatment of vaginal infections.This study was a multicenter, randomized, double-blind, placebo-controlled pilot study in which post-menarchal female subjects between 18 and 65 years of age clinically diagnosed with bacterial vaginosis and vulvovaginal candidiasis were enrolled. The participants were randomized to receive treatment with SilverSol Vagigel or placebo (vehicle) gel (both treatments as one 4 gm application inserted into the vagina with an applicator device, once daily at bedtime for internal use and 2 gm gel for local application to the vulva and vagina for external use twice daily for a period of 14 days). The primary endpoint evaluated was the proportion of subjects achieving clinical cure. The secondary endpoint was the proportion of subjects achieving microbiological cure at the end of the study visit. A total of 57 subjects were randomized in the study out of which 38 subjects were randomized in SilverSol Vagigel arm and 19 subjects were randomized in placebo arm. SilverSol Vagigel significantly improved cure rates of vaginal infections compared to placebo. The proportion of subjects achieving clinical cure of vaginal infections was higher i.e., 33 (86.84%) subjects in SilverSol Vagigel arm compared to 07 (41.18%) subjects in Placebo gel arm (p-value: 0.0009). The clinical cure rate with SilverSol Vagigel was 81.82% (P=0.1758) for bacterial vaginosis and 92.59% (P=0.0010) for vulvovaginal candidiasis patients at the end of the study. Overall SilverSol Vagigel treatment resulted in a significantly higher microbial cure of vaginal infections (P=0.0028) compared to placebo, with a microbial cure rate of 100% for bacterial vaginosis (P=0.0330) and 85.19% for vulvovaginal candidiasis (P=0.0097). No adverse events were reported in subjects treated with SilverSol Vagigel.Colloidal Nano Silver Gel (SilverSol Vagigel) was effective and safe in treating bacterial vaginosis and vulvovaginal candidiasis.
{"title":"A multicentre, randomized, double blind, placebo controlled pilot study to evaluate the efficacy and safety of colloidal Nano silver gel (SilverSol) in the treatment of bacterial vaginosis, vulvovaginal candidiasis and trichomoniasis","authors":"Anirudh Mehta, Saurabh Dani, Alaka Godbole","doi":"10.18231/j.ijogr.2024.015","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.015","url":null,"abstract":"The study evaluated the efficacy and safety of colloidal nano silver gel (SilverSol Vagigel) (A patented technology from American Biotech Labs, USA) in combination with 0.2% lactic acid in the female subjects for the treatment of vaginal infections.This study was a multicenter, randomized, double-blind, placebo-controlled pilot study in which post-menarchal female subjects between 18 and 65 years of age clinically diagnosed with bacterial vaginosis and vulvovaginal candidiasis were enrolled. The participants were randomized to receive treatment with SilverSol Vagigel or placebo (vehicle) gel (both treatments as one 4 gm application inserted into the vagina with an applicator device, once daily at bedtime for internal use and 2 gm gel for local application to the vulva and vagina for external use twice daily for a period of 14 days). The primary endpoint evaluated was the proportion of subjects achieving clinical cure. The secondary endpoint was the proportion of subjects achieving microbiological cure at the end of the study visit. A total of 57 subjects were randomized in the study out of which 38 subjects were randomized in SilverSol Vagigel arm and 19 subjects were randomized in placebo arm. SilverSol Vagigel significantly improved cure rates of vaginal infections compared to placebo. The proportion of subjects achieving clinical cure of vaginal infections was higher i.e., 33 (86.84%) subjects in SilverSol Vagigel arm compared to 07 (41.18%) subjects in Placebo gel arm (p-value: 0.0009). The clinical cure rate with SilverSol Vagigel was 81.82% (P=0.1758) for bacterial vaginosis and 92.59% (P=0.0010) for vulvovaginal candidiasis patients at the end of the study. Overall SilverSol Vagigel treatment resulted in a significantly higher microbial cure of vaginal infections (P=0.0028) compared to placebo, with a microbial cure rate of 100% for bacterial vaginosis (P=0.0330) and 85.19% for vulvovaginal candidiasis (P=0.0097). No adverse events were reported in subjects treated with SilverSol Vagigel.Colloidal Nano Silver Gel (SilverSol Vagigel) was effective and safe in treating bacterial vaginosis and vulvovaginal candidiasis.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.029
Prantik Meddya, Malay Kumar Nandi
A pregnancy which develops outside uterus is called ectopic pregnancy that comprises nearly two percent of total pregnancies. In first case a 25years old female presented with lower abdominal pain and bleeding per vagina with 3 months of amenorrhea and history of irregular oral contraceptive pill use. A live ectopic pregnancy of 12 weeks 3 days gestation found on right fallopian tube during laparotomy and right salpingectomy was done. In second case, a third gravida mother presented with bleeding per vagina and lower abdominal pain with history of 2.5 months of amenorrhea and chronic pelvic inflammatory disease. During laparotomy, both sided hydrosalpinx and left sided live ectopic pregnancy found on the distal end of fallopian tube and left salpingectomy with fimbriectomy with right sided tubal ligation was done. In third case, a third gravida mother with history of lower uterine caesarean section and ruptured left sided tubal ectopic pregnancy previously, presented with lower abdominal pain with 2 months of amenorrhea. Ultrasonography diagnosed a live right sided cornual ectopic pregnancy of 6weeks 6days and conservative management with injection methotrexate was started. Later due to sudden hemodynamic instability, emergency laparotomy was done and ruptured right cornual ectopic pregnancy was found and treated with total abdominal hysterectomy. All these cases were managed successfully. This case series emphasizes that early serological and sonographic diagnosis of location of pregnancy is necessary, there should be high suspicion for ectopic pregnancy even beyond the first trimester and the decision of conservative management in early ectopic pregnancy should be taken judiciously after checking all parameters of the patient.
{"title":"A case series on live ectopic pregnancy","authors":"Prantik Meddya, Malay Kumar Nandi","doi":"10.18231/j.ijogr.2024.029","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.029","url":null,"abstract":"A pregnancy which develops outside uterus is called ectopic pregnancy that comprises nearly two percent of total pregnancies. In first case a 25years old female presented with lower abdominal pain and bleeding per vagina with 3 months of amenorrhea and history of irregular oral contraceptive pill use. A live ectopic pregnancy of 12 weeks 3 days gestation found on right fallopian tube during laparotomy and right salpingectomy was done. In second case, a third gravida mother presented with bleeding per vagina and lower abdominal pain with history of 2.5 months of amenorrhea and chronic pelvic inflammatory disease. During laparotomy, both sided hydrosalpinx and left sided live ectopic pregnancy found on the distal end of fallopian tube and left salpingectomy with fimbriectomy with right sided tubal ligation was done. In third case, a third gravida mother with history of lower uterine caesarean section and ruptured left sided tubal ectopic pregnancy previously, presented with lower abdominal pain with 2 months of amenorrhea. Ultrasonography diagnosed a live right sided cornual ectopic pregnancy of 6weeks 6days and conservative management with injection methotrexate was started. Later due to sudden hemodynamic instability, emergency laparotomy was done and ruptured right cornual ectopic pregnancy was found and treated with total abdominal hysterectomy. All these cases were managed successfully. This case series emphasizes that early serological and sonographic diagnosis of location of pregnancy is necessary, there should be high suspicion for ectopic pregnancy even beyond the first trimester and the decision of conservative management in early ectopic pregnancy should be taken judiciously after checking all parameters of the patient.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-15DOI: 10.18231/j.ijogr.2024.028
Rupita Kulshrestha, Neetu Singh, Mona Mishra
Corpus luteal cyst rupture presents with acute pain abdomen, hemoperitoneum and features of shock. The condition clinically closely mimics acute rupture ectopic pregnancy but has negative urine pregnancy test. Massive hemoperitoneum requires urgent surgical exploration and achievement of hemostasis. Here is a case series describing 3 cases of corpus luteal cyst rupture in patients with diagnosed dengue fever presenting with features of acute abdomen with or without shock at emergency. All were managed surgically, did well in postoperative period, had transfusions of blood and blood products and finally discharged in satisfactory condition. The objective of this series is to highlight the importance of this condition as a differential diagnosis in patients with acute abdomen which is not much described in medical literature.
{"title":"Corpus luteal cyst rupture presenting as massive spontaneous hemoperitoneum in women with dengue infection: A case series","authors":"Rupita Kulshrestha, Neetu Singh, Mona Mishra","doi":"10.18231/j.ijogr.2024.028","DOIUrl":"https://doi.org/10.18231/j.ijogr.2024.028","url":null,"abstract":"Corpus luteal cyst rupture presents with acute pain abdomen, hemoperitoneum and features of shock. The condition clinically closely mimics acute rupture ectopic pregnancy but has negative urine pregnancy test. Massive hemoperitoneum requires urgent surgical exploration and achievement of hemostasis. Here is a case series describing 3 cases of corpus luteal cyst rupture in patients with diagnosed dengue fever presenting with features of acute abdomen with or without shock at emergency. All were managed surgically, did well in postoperative period, had transfusions of blood and blood products and finally discharged in satisfactory condition. The objective of this series is to highlight the importance of this condition as a differential diagnosis in patients with acute abdomen which is not much described in medical literature.","PeriodicalId":13288,"journal":{"name":"Indian Journal of Obstetrics and Gynecology Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139963312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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