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The effect of covid vaccination on menstruation and attitude to the vaccine among Indian women – Results of a prospective survey 接种柯维疫苗对月经的影响以及印度妇女对疫苗的态度--前瞻性调查的结果
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.013
A. Subbian, Jeevithan Shanmugam, Uma Ram
: SARS COV-2 vaccination was a global effort to tackle the Covid-19 pandemic. During the vaccination drive, several concerns were raised about the potential adverse effects of the Covid-19 vaccines, which included the impact on menstruation and fertility in women. This study aimed to assess experiences of Indian Women with covid vaccination and its effects on their menstruation. A prospective web-based survey was conducted targeting women aged 18years and above and who had taken atleast one dose of the covid vaccine. : The total number of responses received were 363. After excluding those with missing details, 342 respondents were included in the analysis. The mean age of the participants was 38.02 ± 7.8 years. 68.1% of the respondents (233/342) reported no change in the periodicity of their cycles post vaccination and 79.5% (272/342) reported no change in the menstrual flow. Forty three women (12.6%) reported experiencing heavy flow post vaccination. In this group which experienced heavy menses, 81.5% (35/43) reported that the heavy menses was self-limiting and did not require any treatment. 9.3% (4/43) of these symptomatic women recorded that short term treatment was sought. Another 9.3% of women reported persisting menstrual changes, at the time of the survey, despite taking prescribed treatment. It was also noted that the changes in menstrual cycles were significantly more in vaccinated nulliparous women.: Covid vaccination appears to have no or little impact on menstrual cycles in two-thirds of the women taking the vaccine. 31.9% of the women in the survey reported some change in their menstrual timing or flow. Most changes were self -limiting. About 1% (4/342) may have longer standing menstrual impact, requiring treatment.
:SARS COV-2 疫苗接种是全球应对 Covid-19 大流行的一项努力。在疫苗接种过程中,人们对 Covid-19 疫苗的潜在不良影响提出了一些担忧,其中包括对女性月经和生育能力的影响。本研究旨在评估印度妇女接种 Covid 疫苗的经历及其对月经的影响。我们针对 18 岁及以上、至少接种过一剂科维疫苗的女性开展了一项前瞻性网络调查。 收到的回复总数为 363 份。在剔除缺失详细信息的受访者后,有 342 名受访者被纳入分析。参与者的平均年龄为 38.02±7.8 岁。68.1%的受访者(233/342)表示接种疫苗后月经周期没有变化,79.5%的受访者(272/342)表示月经量没有变化。有 43 名妇女(12.6%)表示接种疫苗后月经过多。在这组月经过多的妇女中,81.5%(35/43)表示月经过多是自限性的,不需要任何治疗。根据记录,这些有症状的妇女中有 9.3%(4/43)曾寻求短期治疗。另有 9.3%的妇女表示,尽管接受了处方治疗,但在调查时月经仍持续发生变化。调查还注意到,接种疫苗的无阴道妇女的月经周期变化明显更大:接种 Covid 疫苗似乎对三分之二的妇女的月经周期没有影响或影响很小。调查显示,31.9%的妇女的月经时间或月经量发生了一些变化。大多数变化是自限性的。约 1%(4/342)的妇女可能会受到较长时间的月经影响,需要进行治疗。
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引用次数: 0
Transvaginal sonographic diagnosis of caesarean scar ectopic pregnancy: A case report 经阴道超声诊断剖腹产疤痕异位妊娠:病例报告
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.020
S. Lad, Chaya Chourasia, Pavan Gulhane
We report a case of scar ectopic pregnancy which is the rarest type of all ectopic pregnancies. We need to diagnose & treat this condition in the early weeks of pregnancy to avoid the complication. This case of Caesarean scar ectopic pregnancy (CSEP) was diagnosed during an antenatal ultrasound scan, at six weeks of pregnancy. An ultrasound scan of this case revealed the gestation sac in the lower uterine segment at the previous caesarean scar.
我们报告了一例疤痕宫外孕,这是所有宫外孕中最罕见的一种。我们需要在孕早期诊断和治疗这种情况,以避免并发症的发生。这例剖腹产疤痕宫外孕(CSEP)是在怀孕六周时进行产前超声波扫描时被诊断出来的。超声波扫描显示,妊娠囊位于前次剖腹产疤痕处的子宫下段。
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引用次数: 0
Perilous myoma in the puerperium: A case report 产褥期危险肌瘤:病例报告
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.018
Archana Sampath
Leiomyoma, a benign solid tumour found in the female genital tract, affects 3%-13% of pregnancies. These growths occur as sub serosal, intramural, or submucosal tumours. Approximately 10%–30% of pregnant women experience fibroid-related complications, such as spontaneous abortion, preterm labour, soft tissue dystocia, uterine inertia, feto pelvic disproportion, fetal malposition, and postpartum hemorrhage and a higher risk of caesarean delivery. This case report aims to shed light on the complexities arising in the postpartum period for women previously diagnosed with large fibroids during pregnancy. By exploring a specific case, this report emphasizes the importance of understanding and addressing these complications comprehensively. A 27-year-old primigravida sought antenatal care at 8 weeks of gestation with a 6cm intramural fibroid. Her pregnancy progressed smoothly, leading to a healthy vaginal delivery. However, at 7 weeks postpartum, she experienced pelvic discomfort, heavy lochia, and bleeding. Imaging revealed a submucosal fibroid protruding into the endometrial cavity with degenerating component Myomectomy performed. This case underscores the necessity of a comprehensive understanding of complications associated with large fibroids, spanning both the antenatal and postpartum periods. Heightened awareness and timely intervention are crucial to ensuring optimal outcomes for both maternal and foetal health.
子宫肌瘤是女性生殖道中的一种良性实体瘤,占妊娠的 3%-13%。这些肿瘤以浆膜下、壁内或粘膜下肿瘤的形式生长。约 10%-30%的孕妇会出现与子宫肌瘤相关的并发症,如自然流产、早产、软组织难产、子宫惰性、胎盆不称、胎位不正、产后出血以及较高的剖腹产风险。本病例报告旨在阐明曾在妊娠期被诊断出患有巨大子宫肌瘤的妇女在产后出现的复杂情况。通过探讨一个具体病例,本报告强调了全面了解和解决这些并发症的重要性。一名 27 岁的初产妇在妊娠 8 周时因患 6 厘米壁内肌瘤而寻求产前护理。她的孕期进展顺利,最终经阴道健康分娩。然而,在产后 7 周,她出现了盆腔不适、大量白带和出血。影像学检查显示,粘膜下子宫肌瘤突入子宫内膜腔,并伴有变性成分,遂行子宫肌瘤剔除术。本病例强调了全面了解巨大子宫肌瘤相关并发症的必要性,包括产前和产后并发症。提高认识和及时干预对于确保产妇和胎儿的最佳健康结果至关重要。
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引用次数: 0
Nurturing a healthy future: The impact of the mothers' absolute affection (MAA) programme on infant and young child feeding 培育健康的未来:母亲绝对关爱(MAA)计划对婴幼儿喂养的影响
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.030
R. K. Garg
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引用次数: 0
Association of pre-pregnancy body mass index to gestational weight gain, diabetes mellitus and hypertension 孕前体重指数与妊娠体重增加、糖尿病和高血压的关系
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.012
Sreelakshmy K, Shahnas M
: The body mass index (BMI) before pregnancy and gestational weight gain (GWG) may have an association with the outcome of pregnancies. Preeclampsia, gestational diabetes, macrosomia show an association with the BMI. A retrospective analysis of the data collected from 720 pregnant mothers during the period from January 2017 to January 2019 in a tertiary health care centre. The chi-square test was done to assess the categorical data.: Gestational hypertension was significant in overweight women and those who gained weight above recommended range. (22.4% Vs. 0%; p <0.001) GDM was noted in a significant percentage of pregnant women within the recommended weight gain group. (12.4% Vs. 0%; p<0.001).: Pre-pregnancy dietary counselling, physical and lifestyle modifications have a role in bringing down the incidence of GDM and gestational hypertension.
:孕前体重指数(BMI)和妊娠体重增加(GWG)可能与妊娠结果有关。先兆子痫、妊娠糖尿病、巨大儿与体重指数有关。一项回顾性分析收集了一家三级医疗保健中心2017年1月至2019年1月期间720名孕妇的数据。对分类数据进行了卡方检验:超重妇女和体重增加超过建议范围的妇女妊娠高血压显著。(22.4%对0%;P<0.001)建议体重增加组中有相当大比例的孕妇患有妊娠高血压。(12.4%对0%;P<0.001):孕前饮食咨询、身体和生活方式的调整对降低 GDM 和妊娠高血压的发病率有一定作用。
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引用次数: 0
Awareness about cervical cancer risk factors and its prevention among female healthcare professionals in north India 印度北部女性医护人员对宫颈癌风险因素及其预防的认识
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.006
Nidhi Mimani Gupta, Hina Mittal, Neha Kachroo, Neelam Goyal
Cervical cancer stands as the second most prevalent cancer among women in the reproductive age bracket. According to Globocan 2020, there were 604,100 newly diagnosed cases of cervical cancer worldwide, resulting in 341,831 fatalities. In India, there are 436.76 million women aged 15 and older who face the risk of developing cervical cancer. To explore the basic knowledge of cervical cancer, its risk factors, and preventive measures among female healthcare professionals and medical students.A cross-sectional study among all 205 female healthcare providers comprising of doctors, medical students (1st, 2nd & 3rd-year MBBS), and nurses was conducted at Gautam Buddha Chikitsa Mahavidyalaya, Jhajhra, Dehradun, in December 2023. Google Forms platform was used to conduct the pre-composed online survey. Data was entered and analyzed with SPSS software version 26.A maximum number (141) of participants identified HPV infection as a risk factor for cervical cancer followed by multiple sexual partners (137) while 41.95% of subjects knew about early pregnancy as a risk factor for cervical cancer. Knowledge of risk factors for cervical cancer is highest among doctors followed by nurses and students. 81.95% of participants knew that cervical cancer is preventable and screening helps in the prevention of cervical cancer.Regular upgradation of knowledge of female nursing personnel is crucial since women tend to seek advice from them more often. Similarly, HPV and cervical cancer should be strategically incorporated at the beginning of the medical curriculum.
宫颈癌是育龄妇女第二大高发癌症。根据 Globocan 2020 的数据,全球新确诊的宫颈癌病例为 604 100 例,造成 341 831 人死亡。在印度,有 4.3676 亿 15 岁及以上的女性面临罹患宫颈癌的风险。这项横断面研究于 2023 年 12 月在德拉敦 Jhajhra 的 Gautam Buddha Chikitsa Mahavidyalaya 对所有 205 名女性医疗保健提供者(包括医生、医学生(MBBS 一、二、三年级)和护士)进行。调查使用谷歌表格平台进行。最多参与者(141 人)认为 HPV 感染是宫颈癌的风险因素,其次是多个性伴侣(137 人),41.95% 的受试者知道早孕是宫颈癌的风险因素。医生对宫颈癌风险因素的了解程度最高,其次是护士和学生。81.95%的受试者知道宫颈癌是可以预防的,筛查有助于预防宫颈癌。定期提高女性护理人员的知识水平至关重要,因为妇女往往更经常向她们寻求建议。同样,HPV 和宫颈癌也应战略性地纳入医学课程的起始部分。
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引用次数: 0
Correlation between sperm DNA fragmentation index (DFI) with demographic characteristics, sexual history, social habits, chronic illness, BMI: A cross-sectional study 精子 DNA 碎片指数 (DFI) 与人口统计学特征、性史、社会习惯、慢性疾病和体重指数之间的相关性:横断面研究
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.007
Sunil K S, Sunil C V, Apoorva Jain
: During an evaluation of infertile men when all standard semen parameters are normal, a significant proportion of infertile men are found to have increased levels of DNA damage that may adversely affect fertility. To evaluate the correlation between sperm DNA Fragmentation Index (DFI) with demographic characteristics, sexual history, social habits, chronic illness, BMI, physical characteristics, and abstinence period. The current study was carried out among male patients visiting an infertility clinic at SDM College of Medical Sciences and Hospital, Dharwad.The present has shownno statistically significant association between DFI and socio-demographic characteristics like age, married life, contraceptive usage, sexual factors, personal habits, chronic illness, BMI, and physical characteristics of semen analysis like liquefaction and viscosity of the study participants. DFI categories and semen traits including normal forms, head defects, tail defects, amorphous forms, droplet forms, and viable sperms had different means, however these differences (p=0.4378) were not statistically significant.
:在对精液所有标准参数都正常的不育男性进行评估时,发现相当一部分不育男性的 DNA 损伤程度增加,可能会对生育能力产生不利影响。目的:评估精子 DNA 碎片指数(DFI)与人口统计学特征、性史、社会习惯、慢性疾病、体重指数、身体特征和禁欲时间之间的相关性。本研究在达尔瓦德 SDM 医学院和医院不孕不育门诊就诊的男性患者中进行。研究结果表明,精子 DNA 碎片指数(DFI)与研究对象的年龄、婚姻生活、避孕药具使用情况、性因素、个人习惯、慢性疾病、体重指数等社会人口学特征以及精液分析的液化度和粘度等物理特征之间没有统计学意义上的显著关联。DFI 类别和精液特征(包括正常形态、头部缺陷、尾部缺陷、无定形形态、液滴形态和有活力精子)的平均值不同,但这些差异(P=0.4378)在统计学上并不显著。
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引用次数: 0
A multicentre, randomized, double blind, placebo controlled pilot study to evaluate the efficacy and safety of colloidal Nano silver gel (SilverSol) in the treatment of bacterial vaginosis, vulvovaginal candidiasis and trichomoniasis 一项多中心、随机、双盲、安慰剂对照试验研究,评估胶体纳米银凝胶(银溶胶)治疗细菌性阴道病、外阴阴道念珠菌病和滴虫病的疗效和安全性
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.015
Anirudh Mehta, Saurabh Dani, Alaka Godbole
The study evaluated the efficacy and safety of colloidal nano silver gel (SilverSol Vagigel) (A patented technology from American Biotech Labs, USA) in combination with 0.2% lactic acid in the female subjects for the treatment of vaginal infections.This study was a multicenter, randomized, double-blind, placebo-controlled pilot study in which post-menarchal female subjects between 18 and 65 years of age clinically diagnosed with bacterial vaginosis and vulvovaginal candidiasis were enrolled. The participants were randomized to receive treatment with SilverSol Vagigel or placebo (vehicle) gel (both treatments as one 4 gm application inserted into the vagina with an applicator device, once daily at bedtime for internal use and 2 gm gel for local application to the vulva and vagina for external use twice daily for a period of 14 days). The primary endpoint evaluated was the proportion of subjects achieving clinical cure. The secondary endpoint was the proportion of subjects achieving microbiological cure at the end of the study visit. A total of 57 subjects were randomized in the study out of which 38 subjects were randomized in SilverSol Vagigel arm and 19 subjects were randomized in placebo arm. SilverSol Vagigel significantly improved cure rates of vaginal infections compared to placebo. The proportion of subjects achieving clinical cure of vaginal infections was higher i.e., 33 (86.84%) subjects in SilverSol Vagigel arm compared to 07 (41.18%) subjects in Placebo gel arm (p-value: 0.0009). The clinical cure rate with SilverSol Vagigel was 81.82% (P=0.1758) for bacterial vaginosis and 92.59% (P=0.0010) for vulvovaginal candidiasis patients at the end of the study. Overall SilverSol Vagigel treatment resulted in a significantly higher microbial cure of vaginal infections (P=0.0028) compared to placebo, with a microbial cure rate of 100% for bacterial vaginosis (P=0.0330) and 85.19% for vulvovaginal candidiasis (P=0.0097). No adverse events were reported in subjects treated with SilverSol Vagigel.Colloidal Nano Silver Gel (SilverSol Vagigel) was effective and safe in treating bacterial vaginosis and vulvovaginal candidiasis.
该研究评估了胶体纳米银凝胶(SilverSol Vagigel)(美国美国生物技术实验室的专利技术)联合 0.2% 乳酸治疗女性阴道感染的疗效和安全性。该研究是一项多中心、随机、双盲、安慰剂对照试验研究,研究对象为临床诊断为细菌性阴道病和外阴阴道念珠菌病的 18 至 65 岁女性。受试者被随机分配接受 SilverSol Vagigel 或安慰剂(载体)凝胶的治疗(两种治疗方法都是用涂抹器将 4 克凝胶插入阴道,每天睡前一次,供内服;2 克凝胶供外阴和阴道局部外用,每天两次,为期 14 天)。评估的主要终点是达到临床治愈的受试者比例。次要终点是研究结束时微生物治愈的受试者比例。共有 57 名受试者被随机纳入研究,其中 38 名受试者被随机纳入 SilverSol Vagigel 治疗组,19 名受试者被随机纳入安慰剂治疗组。与安慰剂相比,SilverSol Vagigel 能明显提高阴道感染的治愈率。获得阴道感染临床治愈的受试者比例更高,即 SilverSol Vagigel 组的受试者为 33 人(86.84%),而安慰剂组的受试者为 07 人(41.18%)(P 值:0.0009)。研究结束时,细菌性阴道炎患者使用 SilverSol Vagigel 的临床治愈率为 81.82%(P=0.1758),外阴阴道念珠菌病患者的临床治愈率为 92.59%(P=0.0010)。与安慰剂相比,SilverSol Vagigel 治疗阴道感染的微生物治愈率明显更高(P=0.0028),细菌性阴道病的微生物治愈率为 100%(P=0.0330),外阴阴道念珠菌病的微生物治愈率为 85.19%(P=0.0097)。胶体纳米银凝胶(SilverSol Vagigel)在治疗细菌性阴道病和外阴阴道念珠菌病方面既有效又安全。
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引用次数: 0
A case series on live ectopic pregnancy 活体宫外孕病例系列
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.029
Prantik Meddya, Malay Kumar Nandi
A pregnancy which develops outside uterus is called ectopic pregnancy that comprises nearly two percent of total pregnancies. In first case a 25years old female presented with lower abdominal pain and bleeding per vagina with 3 months of amenorrhea and history of irregular oral contraceptive pill use. A live ectopic pregnancy of 12 weeks 3 days gestation found on right fallopian tube during laparotomy and right salpingectomy was done. In second case, a third gravida mother presented with bleeding per vagina and lower abdominal pain with history of 2.5 months of amenorrhea and chronic pelvic inflammatory disease. During laparotomy, both sided hydrosalpinx and left sided live ectopic pregnancy found on the distal end of fallopian tube and left salpingectomy with fimbriectomy with right sided tubal ligation was done. In third case, a third gravida mother with history of lower uterine caesarean section and ruptured left sided tubal ectopic pregnancy previously, presented with lower abdominal pain with 2 months of amenorrhea. Ultrasonography diagnosed a live right sided cornual ectopic pregnancy of 6weeks 6days and conservative management with injection methotrexate was started. Later due to sudden hemodynamic instability, emergency laparotomy was done and ruptured right cornual ectopic pregnancy was found and treated with total abdominal hysterectomy. All these cases were managed successfully. This case series emphasizes that early serological and sonographic diagnosis of location of pregnancy is necessary, there should be high suspicion for ectopic pregnancy even beyond the first trimester and the decision of conservative management in early ectopic pregnancy should be taken judiciously after checking all parameters of the patient.
在子宫外发育的妊娠称为宫外孕,占妊娠总数的近 2%。第一个病例中,一名 25 岁的女性因下腹痛和阴道出血就诊,停经 3 个月,有不规则口服避孕药史。剖腹探查时在右侧输卵管发现妊娠 12 周 3 天的活宫外孕,遂行右侧输卵管切除术。在第二个病例中,一位第三次妊娠的母亲因阴道出血和下腹痛前来就诊,并有 2.5 个月的闭经史和慢性盆腔炎病史。在腹腔镜手术中,发现输卵管远端有双侧积水和左侧活体异位妊娠,于是进行了左侧输卵管切除术和右侧输卵管结扎术。第三个病例是一位孕 3 期的母亲,曾有过子宫下段剖宫产和左侧输卵管异位妊娠破裂的病史,因下腹痛和 2 个月的闭经而就诊。超声波检查诊断为活产的右侧粟粒状异位妊娠,妊娠期为6周6天,并开始注射甲氨蝶呤进行保守治疗。后来,由于血流动力学突然不稳定,医生紧急进行了开腹手术,发现右侧粟粒状异位妊娠破裂,并进行了全腹子宫切除术。所有这些病例都得到了成功的处理。本系列病例强调,有必要及早通过血清学和超声诊断确定妊娠位置,甚至在妊娠头三个月后也应高度怀疑异位妊娠,而且在检查患者的所有指标后,应明智地决定对早期异位妊娠采取保守治疗。
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引用次数: 0
Corpus luteal cyst rupture presenting as massive spontaneous hemoperitoneum in women with dengue infection: A case series 登革热感染妇女的黄体囊肿破裂表现为大量自发性腹腔积血:病例系列
Pub Date : 2024-02-15 DOI: 10.18231/j.ijogr.2024.028
Rupita Kulshrestha, Neetu Singh, Mona Mishra
Corpus luteal cyst rupture presents with acute pain abdomen, hemoperitoneum and features of shock. The condition clinically closely mimics acute rupture ectopic pregnancy but has negative urine pregnancy test. Massive hemoperitoneum requires urgent surgical exploration and achievement of hemostasis. Here is a case series describing 3 cases of corpus luteal cyst rupture in patients with diagnosed dengue fever presenting with features of acute abdomen with or without shock at emergency. All were managed surgically, did well in postoperative period, had transfusions of blood and blood products and finally discharged in satisfactory condition. The objective of this series is to highlight the importance of this condition as a differential diagnosis in patients with acute abdomen which is not much described in medical literature.
黄体囊肿破裂表现为急性腹痛、腹腔积血和休克。这种情况在临床上与急性异位妊娠破裂相似,但尿妊娠试验呈阴性。大面积血性腹腔积液需要紧急手术探查并止血。以下是一个病例系列,描述了 3 例黄体囊肿破裂病例,患者均确诊为登革热,急诊时表现为急腹症,伴有或不伴有休克。所有患者均接受了手术治疗,术后情况良好,输血和血制品,最后均满意出院。这组病例的目的是强调该病作为急腹症患者鉴别诊断的重要性,因为医学文献中对该病的描述并不多。
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引用次数: 0
期刊
Indian Journal of Obstetrics and Gynecology Research
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