Pub Date : 2023-06-28DOI: 10.56042/ijeb.v61i07.2213
{"title":"Association of FokI polymorphism of vitamin D receptor gene with vitamin D and parathyroid hormone levels in stage IV-V chronic kidney disease patients","authors":"","doi":"10.56042/ijeb.v61i07.2213","DOIUrl":"https://doi.org/10.56042/ijeb.v61i07.2213","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41843779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-28DOI: 10.56042/ijeb.v61i07.2826
{"title":"Machine Learning to Predict Etiology for Infectious Diseases of Classic Fever of Unknown Origin in Adults","authors":"","doi":"10.56042/ijeb.v61i07.2826","DOIUrl":"https://doi.org/10.56042/ijeb.v61i07.2826","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43309507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-28DOI: 10.56042/ijeb.v61i07.2211
{"title":"Transcriptional reprogramming under vancomycin pressure in Staphylococcus aureus","authors":"","doi":"10.56042/ijeb.v61i07.2211","DOIUrl":"https://doi.org/10.56042/ijeb.v61i07.2211","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46477374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-28DOI: 10.56042/ijeb.v61i07.3117
{"title":"Effect of exogenous pulmonary surfactant on infectious pneumonia, serum procalcitonin, high-sensitivity C-reactive protein and interleukin-6 in neonates","authors":"","doi":"10.56042/ijeb.v61i07.3117","DOIUrl":"https://doi.org/10.56042/ijeb.v61i07.3117","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48099745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-28DOI: 10.56042/ijeb.v61i07.2323
{"title":"Association of immune status with haematology and inflammatory markers in treatment naïve HIV positive patients from a tertiary health care institute e HIV Positive Patients from a Tertiary Health Care Institute","authors":"","doi":"10.56042/ijeb.v61i07.2323","DOIUrl":"https://doi.org/10.56042/ijeb.v61i07.2323","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49222641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-28DOI: 10.56042/ijeb.v61i07.2212
{"title":"Hypermethylation and reduced expression of lipoprotein metabolism genes ABCG1, LIPC and PLTP in Obese and Diabetic subjects: Potential risk factors for Coronary artery disease","authors":"","doi":"10.56042/ijeb.v61i07.2212","DOIUrl":"https://doi.org/10.56042/ijeb.v61i07.2212","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45309606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-28DOI: 10.56042/ijeb.v61i07.2215
{"title":"Clinical features and biochemical parameters influencing mortality in COVID-19 patients — Retrospective study from Telangana, India","authors":"","doi":"10.56042/ijeb.v61i07.2215","DOIUrl":"https://doi.org/10.56042/ijeb.v61i07.2215","url":null,"abstract":"","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46139791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.56042/ijeb.v61i06.1931
Ay ş egül Yildiz, Süleyman Emre, Ayd ı n Him
Glucagon-like peptide-1 receptors are widely expressed in the brain and its association with nitric oxide is suggestive of its role in epilepsy. In this study, we investigated the effects of exenatide, a glucagon-like peptide-1 receptor agonist, on the epileptiform activity induced by penicillin injection. The study used 72 male Wistar albino rats in 9 groups. All groups except the last group which received only exenatide, received intracortical penicillin injection to induce epileptiform activity. Exenatide was intraperitoneally injected in II-IV groups, at doses of 50, 100, 200 μ g/kg, respectively. Sodium nitroprusside (SNP) and N ω -nitro-L-arginine methyl ester (L-NAME) were injected to the V-VIII groups either alone or with exenatide. Electrocorticography was recorded for 3 h. While administration of 200 μ g/kg exenatide reduced the frequency of epileptiform activity, 50 and 100 μ g/kg doses of exenatide were not effective. When the effective dose of exenatide and the SNP were injected together the spike frequency decreased significantly. When the effective dose of exenatide was given with L-NAME spike frequency significantly decreased only between 90 and 110 min. There was no statistically significant difference in terms of latency and amplitude between the experimental groups. Exenatide had an anticonvulsant effect in penicillin-induced acute epilepsy model which is possibly via nitric oxide and include another pathway since its effect was partially blocked by L-NAME and potentiated by SNP.
{"title":"Antiepileptic effects of exenatide in penicillin induced acute epilepsy model in rats","authors":"Ay ş egül Yildiz, Süleyman Emre, Ayd ı n Him","doi":"10.56042/ijeb.v61i06.1931","DOIUrl":"https://doi.org/10.56042/ijeb.v61i06.1931","url":null,"abstract":"Glucagon-like peptide-1 receptors are widely expressed in the brain and its association with nitric oxide is suggestive of its role in epilepsy. In this study, we investigated the effects of exenatide, a glucagon-like peptide-1 receptor agonist, on the epileptiform activity induced by penicillin injection. The study used 72 male Wistar albino rats in 9 groups. All groups except the last group which received only exenatide, received intracortical penicillin injection to induce epileptiform activity. Exenatide was intraperitoneally injected in II-IV groups, at doses of 50, 100, 200 μ g/kg, respectively. Sodium nitroprusside (SNP) and N ω -nitro-L-arginine methyl ester (L-NAME) were injected to the V-VIII groups either alone or with exenatide. Electrocorticography was recorded for 3 h. While administration of 200 μ g/kg exenatide reduced the frequency of epileptiform activity, 50 and 100 μ g/kg doses of exenatide were not effective. When the effective dose of exenatide and the SNP were injected together the spike frequency decreased significantly. When the effective dose of exenatide was given with L-NAME spike frequency significantly decreased only between 90 and 110 min. There was no statistically significant difference in terms of latency and amplitude between the experimental groups. Exenatide had an anticonvulsant effect in penicillin-induced acute epilepsy model which is possibly via nitric oxide and include another pathway since its effect was partially blocked by L-NAME and potentiated by SNP.","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41887199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.56042/ijeb.v61i06.1942
The marketability of cut flowers relies on its postharvest longevity, making it crucial to develop technologies that can extend its vase life. The vase life in chrysanthemum is dependent upon floret senescence and leaf yellowing. In view of extending the vase life, the present study elucidates the implication of plant growth regulators viz. benzyl adenine (BA), thidiazuron (TDZ) and salicylic acid (SA) on postharvest performance and flower longevity of chrysanthemum stems. The harvested stems were treated with various concentrations viz. BA and SA at 50,100,150 and 200 µM and TDZ at 5,10,15 and 20 µM. Treatments containing 10 µM TDZ and 100 µM BA were most effective in improving the longevity (23.35 and 20.32 days respectively) of cut chrysanthemum stems. However, TDZ outplayed BA followed by SA extends the flower longevity through the maintenance of higher physiological and biochemical characteristics. Cluster analysis inferred that the treatments of 50 and100 µM BA and 5 and10 µM TDZ were found to be efficient in delaying floret senescence (24.01 days) and leaf yellowing (20.54 days) in cut chrysanthemum stems. Postharvest longevity exhibited a positive correlation with antioxidant activities, total soluble sugars and proteins, while it showed a negative correlation with anthocyanin and carotenoid contents. The results have demonstrated that use of growth regulators such as benzyl adenine, thidiazuron and salicylic acid may preserve the quality of cut chrysanthemum stems and delay their senescence
{"title":"Plant growth regulators improved cutting induced physio-biochemical responses to postponement senescence in chrysanthemum","authors":"","doi":"10.56042/ijeb.v61i06.1942","DOIUrl":"https://doi.org/10.56042/ijeb.v61i06.1942","url":null,"abstract":"The marketability of cut flowers relies on its postharvest longevity, making it crucial to develop technologies that can extend its vase life. The vase life in chrysanthemum is dependent upon floret senescence and leaf yellowing. In view of extending the vase life, the present study elucidates the implication of plant growth regulators viz. benzyl adenine (BA), thidiazuron (TDZ) and salicylic acid (SA) on postharvest performance and flower longevity of chrysanthemum stems. The harvested stems were treated with various concentrations viz. BA and SA at 50,100,150 and 200 µM and TDZ at 5,10,15 and 20 µM. Treatments containing 10 µM TDZ and 100 µM BA were most effective in improving the longevity (23.35 and 20.32 days respectively) of cut chrysanthemum stems. However, TDZ outplayed BA followed by SA extends the flower longevity through the maintenance of higher physiological and biochemical characteristics. Cluster analysis inferred that the treatments of 50 and100 µM BA and 5 and10 µM TDZ were found to be efficient in delaying floret senescence (24.01 days) and leaf yellowing (20.54 days) in cut chrysanthemum stems. Postharvest longevity exhibited a positive correlation with antioxidant activities, total soluble sugars and proteins, while it showed a negative correlation with anthocyanin and carotenoid contents. The results have demonstrated that use of growth regulators such as benzyl adenine, thidiazuron and salicylic acid may preserve the quality of cut chrysanthemum stems and delay their senescence","PeriodicalId":13290,"journal":{"name":"Indian journal of experimental biology","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43436784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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