Introduction: Cystoscopy is a common urological procedure done for diagnosis and surveillance of patients with urological ailments. With various lower urinary tract symptoms, flexible cystoscopy can be performed with a minimal discomfort to the patient and in a outpatient setting under local anesthesia. Materials and Methods: We retrospectively analyzed 468 patients undergoing flexible cystoscopy from January 2022 to July 2022 over a period of six months in the outpatient services of B.P. Koirala Memorial Cancer Hospital. Results: Majority of the patients (56.2%) had some pathology of the lower urinary tract among which urinary bladder mass or malignancy was the predominant findings with 35%. Conclusion: Flexible cystoscopy is an important tool in urology with high diagnostic yield.
{"title":"An analysis of flexible cystoscopic findings among patients visiting Urology outpatient services at a tertiary cancer center in Nepal","authors":"U. Nepal, Bharat Mani Pokharel, Sulav Pradhan, Binod Babu Gharti, Gyan Prasad Pokharel, Nirmal Lamichhane","doi":"10.3126/njc.v7i1.60155","DOIUrl":"https://doi.org/10.3126/njc.v7i1.60155","url":null,"abstract":"Introduction: Cystoscopy is a common urological procedure done for diagnosis and surveillance of patients with urological ailments. With various lower urinary tract symptoms, flexible cystoscopy can be performed with a minimal discomfort to the patient and in a outpatient setting under local anesthesia. Materials and Methods: We retrospectively analyzed 468 patients undergoing flexible cystoscopy from January 2022 to July 2022 over a period of six months in the outpatient services of B.P. Koirala Memorial Cancer Hospital. Results: Majority of the patients (56.2%) had some pathology of the lower urinary tract among which urinary bladder mass or malignancy was the predominant findings with 35%. Conclusion: Flexible cystoscopy is an important tool in urology with high diagnostic yield.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139335551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chin Bahadur Pun Magar, R. Bhatta, G. Pandey, S. Uprety, I. Dhungana, N. Jha
Introduction: Colorectal carcinoma is primary epithelial malignancy arising in the colorectum areas. 98% of colonic and rectum cancers are adenocarcinomas. The prevalence of colorectal cancer has been dramatically growing at an alarming rate globally in recent years. Materials and methods: This is retrospective study at Department of Pathology in B P Koirala Memorial Cancer Hospital effective from 1st January 2018 to 31st December 2019. All the data were retrieved and analyzed. Results:Total 56 colorectal cancer cases were analyzed, among them 36 cases were males accounting 64 % and 20 cases were females accounting 36 %. Rectum was the commonest site and commonest age group was 61-70 years accounting 55.3%. 44.6% cases were in advanced stage either stage III or IV. Conclusion:Colorectal cancer is more common in males than in females. Most commonly affected age group was 61-70 years. Most common histological type was well differentiated adenocarcinoma. 44.6% cases were diagnosed in advanced stage either stage III or IV.
{"title":"An Overview of Colorectal Cancer in Tertiary care Cancer Center of Nepal","authors":"Chin Bahadur Pun Magar, R. Bhatta, G. Pandey, S. Uprety, I. Dhungana, N. Jha","doi":"10.3126/njc.v6i2.48766","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48766","url":null,"abstract":"Introduction: Colorectal carcinoma is primary epithelial malignancy arising in the colorectum areas. 98% of colonic and rectum cancers are adenocarcinomas. The prevalence of colorectal cancer has been dramatically growing at an alarming rate globally in recent years.\u0000Materials and methods: This is retrospective study at Department of Pathology in B P Koirala Memorial Cancer Hospital effective from 1st January 2018 to 31st December 2019. All the data were retrieved and analyzed.\u0000Results:Total 56 colorectal cancer cases were analyzed, among them 36 cases were males accounting 64 % and 20 cases were females accounting 36 %. Rectum was the commonest site and commonest age group was 61-70 years accounting 55.3%. 44.6% cases were in advanced stage either stage III or IV.\u0000Conclusion:Colorectal cancer is more common in males than in females. Most commonly affected age group was 61-70 years. Most common histological type was well differentiated adenocarcinoma. 44.6% cases were diagnosed in advanced stage either stage III or IV.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126162813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sailuja Maharjan, B. Satyal, Reena Baidya, P. Neupane
Primary amelanotic melanoma of rectum is a very rare tumor accounting for less than 2% of melanomas. It is a highly aggressive tumor that often tends to invade lymph nodes or metastasize in the early course of disease. The prognosis of this tumor is very bismal with five year survival of less than 20%. We report a case of primary amelanotic melanoma of anorectum in which preoperative biopsy was inconclusive, thus highlighting the role of immunohistochemical markers to reach to a correct diagnosis. This is the first case of amelanotic anorectal melanoma reported from Nepal.
{"title":"Primary Anorectal Amelanotic Melanoma: Case Report and Review of Literature","authors":"Sailuja Maharjan, B. Satyal, Reena Baidya, P. Neupane","doi":"10.3126/njc.v6i2.48771","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48771","url":null,"abstract":"Primary amelanotic melanoma of rectum is a very rare tumor accounting for less than 2% of melanomas. It is a highly aggressive tumor that often tends to invade lymph nodes or metastasize in the early course of disease. The prognosis of this tumor is very bismal with five year survival of less than 20%. We report a case of primary amelanotic melanoma of anorectum in which preoperative biopsy was inconclusive, thus highlighting the role of immunohistochemical markers to reach to a correct diagnosis. This is the first case of amelanotic anorectal melanoma reported from Nepal.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130469526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
U. Nepal, Binod Babu Gharti, B. Pokharel, G. Pandey, Pradipti Adhikari, N. Lamichhane
Introduction: Carcinoma of Penis is not an uncommon disease in Nepal and comprises 1-10% of all the malignancies in males. The objective of this study is to retrospectively analyze the geographical distribution of these patients who visited Urology clinics at B P Koirala Memorial Cancer Hospital (BPKMCH), Bharatpur, Nepal during the specified time period. Materials and Methods:Altogether 183 patients from January 2012 to December 2016 with penile cancer were included. All others who had incomplete information about their address or those patients from neighboring countries were excluded. Data was collected and analyzed to find out the commonest provinces and districts in the country with the disease. Results: Madhesh Province also known as province No 2 was found to have the maximum disease burden. Out of the total 183 patients analysed, 87 were from Madhesh Province. The ratio of patients coming from this province was much more as compared to other provinces in the country. All the districts in this province showed a large disease burden with the maximum number of patients coming from Sarahi and Siraha districts. We did not receive any patient from Karnali Province during the specified time Period. Conclusions: Considering the fact that we are receiving a large number of patients from Madhesh province, we think we have to start educating the public in those districts. Regular early detection health camps to evaluate for any genital symptoms or lesions would have been beneficial. Educating them of hygiene, initiating vaccination programs would benefit. Remoteness of Karnali Province might have caused nil patient visiting for care. It can be proposed that government service and hospital services should reach these places to serve these remote areas.
{"title":"Geographical Distribution Of Carcinoma Penis patients from Nepal: Retrospective analysis from a tertiary care cancer centre","authors":"U. Nepal, Binod Babu Gharti, B. Pokharel, G. Pandey, Pradipti Adhikari, N. Lamichhane","doi":"10.3126/njc.v6i2.48763","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48763","url":null,"abstract":"Introduction: Carcinoma of Penis is not an uncommon disease in Nepal and comprises 1-10% of all the malignancies in males. The objective of this study is to retrospectively analyze the geographical distribution of these patients who visited Urology clinics at B P Koirala Memorial Cancer Hospital (BPKMCH), Bharatpur, Nepal during the specified time period.\u0000Materials and Methods:Altogether 183 patients from January 2012 to December 2016 with penile cancer were included. All others who had incomplete information about their address or those patients from neighboring countries were excluded. Data was collected and analyzed to find out the commonest provinces and districts in the country with the disease.\u0000Results: Madhesh Province also known as province No 2 was found to have the maximum disease burden. Out of the total 183 patients analysed, 87 were from Madhesh Province. The ratio of patients coming from this province was much more as compared to other provinces in the country. All the districts in this province showed a large disease burden with the maximum number of patients coming from Sarahi and Siraha districts. We did not receive any patient from Karnali Province during the specified time Period.\u0000Conclusions: Considering the fact that we are receiving a large number of patients from Madhesh province, we think we have to start educating the public in those districts. Regular early detection health camps to evaluate for any genital symptoms or lesions would have been beneficial. Educating them of hygiene, initiating vaccination programs would benefit. Remoteness of Karnali Province might have caused nil patient visiting for care. It can be proposed that government service and hospital services should reach these places to serve these remote areas.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117278181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To analyze the effect of multi-directional continuous nursing on improving the quality of life of patients with cancer pain after discharge. Methods: According to the method of random number table, 80 patients with cancer pain were divided into control group and intervention group, with 40 patients in each group. The control group received routine nursing and the intervention group received multi-directional continuous nursing. The quality of life of the two groups before and after nursing were compared and observed, and the satisfaction score was investigated. Results: The quality of life in the intervention group was higher than that in the control group (P<0.05); The nursing satisfaction of the intervention group was higher than that of the control group (P<0.05). Conclusion: The implementation of multi-directional continuous nursing for cancer pain patients can improve the quality of life and increase the satisfaction of patients.
{"title":"Effect of continuous nursing on quality of life and pain management of patients with cancer pain","authors":"Xiaolei Yu, Wenxin Li, Qingshan Li","doi":"10.3126/njc.v6i2.48756","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48756","url":null,"abstract":"Objective: To analyze the effect of multi-directional continuous nursing on improving the quality of life of patients with cancer pain after discharge.\u0000Methods: According to the method of random number table, 80 patients with cancer pain were divided into control group and intervention group, with 40 patients in each group. The control group received routine nursing and the intervention group received multi-directional continuous nursing. The quality of life of the two groups before and after nursing were compared and observed, and the satisfaction score was investigated.\u0000Results: The quality of life in the intervention group was higher than that in the control group (P<0.05); The nursing satisfaction of the intervention group was higher than that of the control group (P<0.05).\u0000Conclusion: The implementation of multi-directional continuous nursing for cancer pain patients can improve the quality of life and increase the satisfaction of patients.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"6 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114107035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swechha Maskey, S. Karki, A. Pradhan, P. Paudyal, C. Agrawal
Background: Angiogenesis plays an important role in carcinogenesis. Angiogenesis is studied by calculating the microvessel density. The purpose of this study is to determine whether angiogenesis can be documented in colorectal tumor progression and to assess whether the quantification of microvessels can be correlated to tumor aggressiveness. Methods: This is a hospital based descriptive cross-sectional study, done from August 2015 to July 2016 after obtaining ethical approval from Institutional Review Committee. We quantified microvessel density in colorectal carcinoma. An immunohistochemical study was performed using mouse monoclonal antibody against CD34, which was used for localizing endothelial cell lined blood vessels & cluster of endothelial cells without lumen formation. Counting was done in 10 consecutive high power fields (40x). The data were analyzed after the counting was done. Results: We compared microvessel density with age, gender, tumor size, histologic differentiation, tumoral invasion, lymph node metastasis and tumor stage. No significant correlation was found between microvessel density and the aforementioned parameters (p>0.05). Conclusions: The correlation between microvessel density and tumor progression was non-significant. Hence we conclude that there is a need to undertake studies involving larger samples, and also assessment of the other factors associated with angiogenesis should be done to have a better information on prognostic values
{"title":"Angiogenesis in Colorectal Carcinoma: An Immunohistochemical study","authors":"Swechha Maskey, S. Karki, A. Pradhan, P. Paudyal, C. Agrawal","doi":"10.3126/njc.v6i2.48772","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48772","url":null,"abstract":"Background: Angiogenesis plays an important role in carcinogenesis. Angiogenesis is studied by calculating the microvessel density. The purpose of this study is to determine whether angiogenesis can be documented in colorectal tumor progression and to assess whether the quantification of microvessels can be correlated to tumor aggressiveness.\u0000Methods: This is a hospital based descriptive cross-sectional study, done from August 2015 to July 2016 after obtaining ethical approval from Institutional Review Committee. We quantified microvessel density in colorectal carcinoma. An immunohistochemical study was performed using mouse monoclonal antibody against CD34, which was used for localizing endothelial cell lined blood vessels & cluster of endothelial cells without lumen formation. Counting was done in 10 consecutive high power fields (40x). The data were analyzed after the counting was done.\u0000Results: We compared microvessel density with age, gender, tumor size, histologic differentiation, tumoral invasion, lymph node metastasis and tumor stage. No significant correlation was found between microvessel density and the aforementioned parameters (p>0.05).\u0000Conclusions: The correlation between microvessel density and tumor progression was non-significant. Hence we conclude that there is a need to undertake studies involving larger samples, and also assessment of the other factors associated with angiogenesis should be done to have a better information on prognostic values","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124614108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Thakur, M. Devkota, Nikesh Bhandari, Shashank Shrestha, Ashish Kharel
Background: Esophagectomy is a complex operation. Minimally invasive esophagectomy (MIE) may decrease the morbidity and mortality of resection. The aim of this study was to produce long term outcome of MIE from a single center in Nepal. Methods: Patients with squamous cell carcinoma and adenocarcinoma of esophagus/ gastroesophageal junction who underwent MIE between 2001-2018 were analyzed. Results: 215 patients were taken for MIE during 2001-2018. There was 11.2% conversion rate. Totally MIE approach was performed in 43% cases and hybrid MIE in 57% cases. Mean operative time, intra operative blood loss, anastomotic leak, pulmonary infection, recurrent laryngeal nerve injury and in-hospital mortality were 246 min, 286 ml, 13.1%, 9%, 6.8% and 3%, respectively. Final histopathology revealed most common Stages III and IV in 51.2% and 36.1%, respectively. The median survival was 34 months and 5-OS was 27%. 5-OS was 27% and o% for R0 and R+ resection (p<.001). Median survival after radical and non-radical lymphadenectomy was 36 months and 25 months (p=.003), respectively. Responders to neoadjuvant treatment had the best survival. Conclusion: MIE has got acceptable post operative morbidities. R0 resection, early stage of disease, radical lymphadenectomy and responders to neoadjuvant treatment had got the best survival results
{"title":"Minimally invasive esophagectomy/ gastroesophagectomy for cancer - Long term results from a single institution","authors":"B. Thakur, M. Devkota, Nikesh Bhandari, Shashank Shrestha, Ashish Kharel","doi":"10.3126/njc.v6i2.48754","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48754","url":null,"abstract":"Background: Esophagectomy is a complex operation. Minimally invasive esophagectomy (MIE) may decrease the morbidity and mortality of resection. The aim of this study was to produce long term outcome of MIE from a single center in Nepal.\u0000Methods: Patients with squamous cell carcinoma and adenocarcinoma of esophagus/ gastroesophageal junction who underwent MIE between 2001-2018 were analyzed.\u0000Results: 215 patients were taken for MIE during 2001-2018. There was 11.2% conversion rate. Totally MIE approach was performed in 43% cases and hybrid MIE in 57% cases. Mean operative time, intra operative blood loss, anastomotic leak, pulmonary infection, recurrent laryngeal nerve injury and in-hospital mortality were 246 min, 286 ml, 13.1%, 9%, 6.8% and 3%, respectively. Final histopathology revealed most common Stages III and IV in 51.2% and 36.1%, respectively. The median survival was 34 months and 5-OS was 27%. 5-OS was 27% and o% for R0 and R+ resection (p<.001). Median survival after radical and non-radical lymphadenectomy was 36 months and 25 months (p=.003), respectively. Responders to neoadjuvant treatment had the best survival.\u0000Conclusion: MIE has got acceptable post operative morbidities. R0 resection, early stage of disease, radical lymphadenectomy and responders to neoadjuvant treatment had got the best survival results","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125696006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Lamichhane, Suraj Suwal, R. Rana, Rishikesh Narayan Shrestha
Introduction: Patients are kept nil per oral (NPO) after surgery for gastric cancer and all patients receives intravenous fluids till oral feed is commenced. There is established benefit of enteral nutrition after surgery for gastric cancer. Early oral feeding comes with lots of hesitation for execution, so to offer benefits of early enteral nutrition and to avoid early oral feeding, nasojejunal tube (NJ) feeding can be used as alternative to feeding jejunostomy (FJ) and also total parenteral nutrition (TPN) can be avoided. The aim of this study is to present our experience of early enteral feeding using NJ tube and to convey the message that early feeding using NJ tube is safe, effective and has less complications. Methods: This is a retrospective study of patients operated between April 2019 to March 2022, who had nasojejunal tube placed at the time of surgery. NJ tube was placed in the efferent limb of jejunum. Feeding was started from post operative day 1 and gradually progressed over days. NJ tube was removed after adequate oral intake. Results: Sixty patients were eligible for final analysis. Median age of patients was 61 years, IQR (53-69). Thirty-three patients underwent D2-subtotal gastrectomy, 16 underwent D2-total gastrectomy and 10 underwent gastro-jejunostomy. Median time for discharge is 12 days, IQR (12-14). The median time for NJ removal is 10 days, IQR (9-12). Thirty-four patients reported complications related to NJ feed, all were minor and easily manageable. Conclusion: NJ tube feeding offers the advantages of early enteral feeding after gastric cancer surgery. It is technically easy to use and should be advocated for its simplicity, low costs and great advantages as compared to FJ and TPN.
{"title":"Early enteral feeding using nasojejunal tube after gastric cancer surgery is safe and effective: a single unit experience from cancer hospital","authors":"D. Lamichhane, Suraj Suwal, R. Rana, Rishikesh Narayan Shrestha","doi":"10.3126/njc.v6i2.48755","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48755","url":null,"abstract":"Introduction: Patients are kept nil per oral (NPO) after surgery for gastric cancer and all patients receives intravenous fluids till oral feed is commenced. There is established benefit of enteral nutrition after surgery for gastric cancer. Early oral feeding comes with lots of hesitation for execution, so to offer benefits of early enteral nutrition and to avoid early oral feeding, nasojejunal tube (NJ) feeding can be used as alternative to feeding jejunostomy (FJ) and also total parenteral nutrition (TPN) can be avoided. The aim of this study is to present our experience of early enteral feeding using NJ tube and to convey the message that early feeding using NJ tube is safe, effective and has less complications.\u0000Methods: This is a retrospective study of patients operated between April 2019 to March 2022, who had nasojejunal tube placed at the time of surgery. NJ tube was placed in the efferent limb of jejunum. Feeding was started from post operative day 1 and gradually progressed over days. NJ tube was removed after adequate oral intake.\u0000Results: Sixty patients were eligible for final analysis. Median age of patients was 61 years, IQR (53-69). Thirty-three patients underwent D2-subtotal gastrectomy, 16 underwent D2-total gastrectomy and 10 underwent gastro-jejunostomy. Median time for discharge is 12 days, IQR (12-14). The median time for NJ removal is 10 days, IQR (9-12). Thirty-four patients reported complications related to NJ feed, all were minor and easily manageable.\u0000Conclusion: NJ tube feeding offers the advantages of early enteral feeding after gastric cancer surgery. It is technically easy to use and should be advocated for its simplicity, low costs and great advantages as compared to FJ and TPN.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"212 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133797939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashish Kharel, Shashank Shrestha, Nikesh Bhandari, B. Thakur
Primary malignant sternal tumors are rare clinical entities. We came across two such patients with primary sternal tumors. One was a chondroblastic osteosarcoma while the other was a chondrosarcoma. One patient received neoadjuvant chemotherapy followed by surgery. The second patient underwent upfront surgery. Both cases received wide excision of the tumor (sternum along with part of medial ends of bilateral clavicles and upper ribs). Reconstruction was done using autologous bone graft with prolene mesh in one case and titanium reconstruction plates in the other case. Both cases received coverage with pectoralis major muscle flaps.
{"title":"Malignant Sternal Tumors: Report of Two Cases","authors":"Ashish Kharel, Shashank Shrestha, Nikesh Bhandari, B. Thakur","doi":"10.3126/njc.v6i2.48765","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48765","url":null,"abstract":"Primary malignant sternal tumors are rare clinical entities. We came across two such patients with primary sternal tumors. One was a chondroblastic osteosarcoma while the other was a chondrosarcoma. One patient received neoadjuvant chemotherapy followed by surgery. The second patient underwent upfront surgery. Both cases received wide excision of the tumor (sternum along with part of medial ends of bilateral clavicles and upper ribs). Reconstruction was done using autologous bone graft with prolene mesh in one case and titanium reconstruction plates in the other case. Both cases received coverage with pectoralis major muscle flaps.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132504062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Acharya, Gambhir Shrestha, P. Neupane, N. Lamichhane
Background: Cancer is a major public health problem in the world. This study aims to present a three-year trend of cancer incidence in Nepal. Methods: This study used the three-year data of National Cancer Registry Program (NCRP) from January 2013 to December 2015. NCRP currently includes 12 major hospitals where diagnostic treatment facilities are available and represent the majority of the cases in Nepal. Descriptive analysis was used to present the demographic profile of the participants and the incidence of different topography of cancer. Age-specific and age-adjusted cancer incidence per 100,000 population were presented. Results: A total of 27,483 new cancer cases were included in the study. The age-adjusted incidence rates were 39.1, 39.8 and 41.8 per 100,000 population in the year 2013, 2014 and 2015 respectively. The most common cancer in Nepal was lung followed by cervical, breast, stomach and colorectal cancer. Among males, lung cancer was the most common followed by lip and oral cavity, stomach, colorectal cancer and leukemia and among females, cervical cancer followed by breast, lung, ovary and stomach. Conclusion: Cancer incidence is rising in Nepal and thus comprehensive policies targeting prevention, early detection, and treatment programs should be carried out.
{"title":"Incidence of Cancer in Nepal: A Three-Year Trend Analysis","authors":"B. Acharya, Gambhir Shrestha, P. Neupane, N. Lamichhane","doi":"10.3126/njc.v6i2.58214","DOIUrl":"https://doi.org/10.3126/njc.v6i2.58214","url":null,"abstract":"Background: Cancer is a major public health problem in the world. This study aims to present a three-year trend of cancer incidence in Nepal. \u0000Methods: This study used the three-year data of National Cancer Registry Program (NCRP) from January 2013 to December 2015. NCRP currently includes 12 major hospitals where diagnostic treatment facilities are available and represent the majority of the cases in Nepal. Descriptive analysis was used to present the demographic profile of the participants and the incidence of different topography of cancer. Age-specific and age-adjusted cancer incidence per 100,000 population were presented. \u0000Results: A total of 27,483 new cancer cases were included in the study. The age-adjusted incidence rates were 39.1, 39.8 and 41.8 per 100,000 population in the year 2013, 2014 and 2015 respectively. The most common cancer in Nepal was lung followed by cervical, breast, stomach and colorectal cancer. Among males, lung cancer was the most common followed by lip and oral cavity, stomach, colorectal cancer and leukemia and among females, cervical cancer followed by breast, lung, ovary and stomach. \u0000Conclusion: Cancer incidence is rising in Nepal and thus comprehensive policies targeting prevention, early detection, and treatment programs should be carried out.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121170321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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