Nikesh Bhandari, B. Thakur, Shashank Shrestha, Ashish Kharel
Ultrasound (US) is a very common tool in today’s clinical practice. Lung ultrasound was popularized by Daniel Lichtenstein, a French intensivist. He noted that sonographic artifacts during lung ultrasound could differentiate between various lung diseases and subsequently noted the ultrasound’s ability to differentiate various diseases. He also popularized the points of probe placement and various signs and lines in lung ultrasound, which includes the A line, B-lines, Lung sliding sign, seashore sign etc. based upon which the BLUE protocol was introduced. Lung ultrasound has rapidly gained popularity over the past 10 years, mainly due to its wide availability in emergency and trauma settings, lack of radiation exposure, easy availability and cost effectiveness. Although there are limitation to Lung ultrasound, like being user dependent, limited role in surgical emphysema, in severely obese patients, and CT still remains a gold standard for diagnosis of lung pathologies, ultrasound has shown to be equally effective or even better in diagnosis and management of patients in critically ill patients, where obtaining CT scan or other imaging technique is not feasible. Hence, lung ultrasound is a must have tool and knowledge and skills related to lung ultrasound should not only be limited to Radiologist, but also to all thoracic surgeons and physicians involved in managing critically ill patients.
{"title":"Ultrasound of Lung","authors":"Nikesh Bhandari, B. Thakur, Shashank Shrestha, Ashish Kharel","doi":"10.3126/njc.v6i2.48770","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48770","url":null,"abstract":"Ultrasound (US) is a very common tool in today’s clinical practice. Lung ultrasound was popularized by Daniel Lichtenstein, a French intensivist. He noted that sonographic artifacts during lung ultrasound could differentiate between various lung diseases and subsequently noted the ultrasound’s ability to differentiate various diseases. He also popularized the points of probe placement and various signs and lines in lung ultrasound, which includes the A line, B-lines, Lung sliding sign, seashore sign etc. based upon which the BLUE protocol was introduced. Lung ultrasound has rapidly gained popularity over the past 10 years, mainly due to its wide availability in emergency and trauma settings, lack of radiation exposure, easy availability and cost effectiveness. Although there are limitation to Lung ultrasound, like being user dependent, limited role in surgical emphysema, in severely obese patients, and CT still remains a gold standard for diagnosis of lung pathologies, ultrasound has shown to be equally effective or even better in diagnosis and management of patients in critically ill patients, where obtaining CT scan or other imaging technique is not feasible. Hence, lung ultrasound is a must have tool and knowledge and skills related to lung ultrasound should not only be limited to Radiologist, but also to all thoracic surgeons and physicians involved in managing critically ill patients.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131426676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shashank Shrestha, B. Thakur, M. Devkota, Nikesh Bhandari, Ashish Kharel, A. Thapa
Background: Fiberoptic bronchoscopy is the most important diagnostic tool for lung cancer. Early tissue diagnosis and proper staging remains the key to the management of the lung cancer patient. Endobronchial forceps biopsy has high diagnostic yield from the visible lesions. The aim of the study was to evaluate diagnostic yield of endobronchial biopsy. Methods: A retrospective cross-sectional study was conducted at B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal. Bronchoscopy reports of 1074 patients from January 2000 to December 2009 were included. Endobronchial biopsy was the main procedure performed. Results: A total of 1074 patients underwent bronchoscopy for suspected lung cancer. Majority of the patients (N=340) had lesion in lobar bronchus. Squamous cell carcinoma was the most common histological diagnosis. The diagnostic yield of endobronchial biopsy was 75%. The diagnostic yield for central tumor was 82.3% which was statistically significant (p<0.001) compared to peripheral tumor and extrinsic compression. Conclusion: Endobronchial biopsy provides good diagnostic yield especially in central tumors. Fiberoptic bronchoscopy is a safe procedure.
{"title":"Bronchoscopy findings in 1074 lung cancer patients in a tertiary care center in Nepal","authors":"Shashank Shrestha, B. Thakur, M. Devkota, Nikesh Bhandari, Ashish Kharel, A. Thapa","doi":"10.3126/njc.v6i2.48767","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48767","url":null,"abstract":"Background: Fiberoptic bronchoscopy is the most important diagnostic tool for lung cancer. Early tissue diagnosis and proper staging remains the key to the management of the lung cancer patient. Endobronchial forceps biopsy has high diagnostic yield from the visible lesions. The aim of the study was to evaluate diagnostic yield of endobronchial biopsy.\u0000Methods: A retrospective cross-sectional study was conducted at B.P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal. Bronchoscopy reports of 1074 patients from January 2000 to December 2009 were included. Endobronchial biopsy was the main procedure performed.\u0000Results: A total of 1074 patients underwent bronchoscopy for suspected lung cancer. Majority of the patients (N=340) had lesion in lobar bronchus. Squamous cell carcinoma was the most common histological diagnosis. The diagnostic yield of endobronchial biopsy was 75%. The diagnostic yield for central tumor was 82.3% which was statistically significant (p<0.001) compared to peripheral tumor and extrinsic compression.\u0000Conclusion: Endobronchial biopsy provides good diagnostic yield especially in central tumors. Fiberoptic bronchoscopy is a safe procedure.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131569233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To study the protective effect of Esculetin on myocardial injury induced by doxorubicin and explore the mechanism of doxorubicin on myocardial injury in rats. Methods: Doxorubicin(2.5mg/kg) was injected intraperitoneally every other day for 6 times to establish a rat model of myocardial injury. The effects of different doses of Esculetin (10mg/kg & 20mg/kg) on serum myocardial enzymes and myocardial tissue were observed. Results: Doxorubicin significantly increased serum myocardial enzymes and the content of myocardial interstitial collagen fibers in mice. Different doses of Esculetin could reduce myocardial injury in a dose-dependent manner. Conclusion: Esculetin has a protective effect on myocardial injury induced by doxorubicin.
{"title":"Protective effect of Esculetin on myocardial injury induced by doxorubicin","authors":"Fan Xu, Xiao Li, Xiaolei Yu","doi":"10.3126/njc.v6i2.48773","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48773","url":null,"abstract":"Objective: To study the protective effect of Esculetin on myocardial injury induced by doxorubicin and explore the mechanism of doxorubicin on myocardial injury in rats.\u0000Methods: Doxorubicin(2.5mg/kg) was injected intraperitoneally every other day for 6 times to establish a rat model of myocardial injury. The effects of different doses of Esculetin (10mg/kg & 20mg/kg) on serum myocardial enzymes and myocardial tissue were observed.\u0000Results: Doxorubicin significantly increased serum myocardial enzymes and the content of myocardial interstitial collagen fibers in mice. Different doses of Esculetin could reduce myocardial injury in a dose-dependent manner.\u0000Conclusion: Esculetin has a protective effect on myocardial injury induced by doxorubicin.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133408845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To investigate the correlation between clinico-pathological features and lymph node metastasis of papillary thyroid microcarcinoma (PTMC). Methods: The clinico-pathological data of 142 cases of papillary thyroid microcarcinoma were collected. The relationship between sex, age, tumor location, multi-focality and cervical lymph node metastasis were analyzed. Results: There was increased rate of lymph node metastasis in male patients with PTMC. There was no significant correlation between age, multifocality and lymph node metastasis. Conclusion: The histological subtypes of PTMC have different clinicopathological characteristics and are important factors for cervical lymph node metastasis. Further evaluation of its histological classification is helpful for clinical treatment strategy.
{"title":"Risk factors of lymph node metastasis in central region in Papillary thyroid micro carcinoma","authors":"Xing Zhao, Ming Zhao, Gang Zhang","doi":"10.3126/njc.v6i2.48764","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48764","url":null,"abstract":"Objective: To investigate the correlation between clinico-pathological features and lymph node metastasis of papillary thyroid microcarcinoma (PTMC).\u0000Methods: The clinico-pathological data of 142 cases of papillary thyroid microcarcinoma were collected. The relationship between sex, age, tumor location, multi-focality and cervical lymph node metastasis were analyzed.\u0000Results: There was increased rate of lymph node metastasis in male patients with PTMC. There was no significant correlation between age, multifocality and lymph node metastasis.\u0000Conclusion: The histological subtypes of PTMC have different clinicopathological characteristics and are important factors for cervical lymph node metastasis. Further evaluation of its histological classification is helpful for clinical treatment strategy.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121460172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Being in the close vicinity, chances of ureteral injury is high while doing radical operation for cervical cancer. Although the incidence is low, if it is not found during the operation, it can lead to serious complications such as urinary fistula. Timely detection and repair of ureteral injury can reduce the occurrence of serious complications.The placement of ureteral catheter before radical hysterectomy can be a good method to identify the ureter during operation to prevent injury.The objective of the study was to explore the advantages and disadvantages of the placement of ureteral catheter in radical operation of cervical cancer. Methods: 103 patients who were diagnosed as cervical cancer and underwent operation in the department of Obstetrics and Gynecology, Jinling Hospital from January 2019 to April 2020 were analyzed in this study. The clinical stage ranges from IA to IIA. Among them, 23 cases were placed with double J stent before operation (observation group), 80 cases were operated without stent (control group). The intra-operative condition, operation and postoperative complications were analyzed retrospectively. Results: There was a significant difference in the operation time and intra-operative blood loss between the two groups (P< 0.05), and there was no significant difference in blood transfusion between the two groups (P> 0.05). There was no significant difference in the incidence of urinary tract infection and urinary retention between the two groups (P> 0.05). The incidence of postoperative hematuria (including microscopic hematuria) was significant in two groups（P< 0.05). Ureteric injury occurred in the 9 patients in the control group (11.25%). Conclusion: Ureteral catheter inserted before radical operation of cervical cancer can help to identify the ureter easily, decrease urinary tract injury, shorten operation time and reduce intra-operative blood loss, and will not increase urinary retention and urinary tract infection. It is safe and effective method especially for young gynecologists.
{"title":"Clinical Value of Ureteral Catheterization before Trans-abdominal Radical Hysterectomy and Pelvic Lymphadenectomy","authors":"Yong Zhang, Xiao-ying Yin, Jin-Xia Liu","doi":"10.3126/njc.v6i2.48753","DOIUrl":"https://doi.org/10.3126/njc.v6i2.48753","url":null,"abstract":"Introduction: Being in the close vicinity, chances of ureteral injury is high while doing radical operation for cervical cancer. Although the incidence is low, if it is not found during the operation, it can lead to serious complications such as urinary fistula. Timely detection and repair of ureteral injury can reduce the occurrence of serious complications.The placement of ureteral catheter before radical hysterectomy can be a good method to identify the ureter during operation to prevent injury.The objective of the study was to explore the advantages and disadvantages of the placement of ureteral catheter in radical operation of cervical cancer.\u0000Methods: 103 patients who were diagnosed as cervical cancer and underwent operation in the department of Obstetrics and Gynecology, Jinling Hospital from January 2019 to April 2020 were analyzed in this study. The clinical stage ranges from IA to IIA. Among them, 23 cases were placed with double J stent before operation (observation group), 80 cases were operated without stent (control group). The intra-operative condition, operation and postoperative complications were analyzed retrospectively.\u0000Results: There was a significant difference in the operation time and intra-operative blood loss between the two groups (P< 0.05), and there was no significant difference in blood transfusion between the two groups (P> 0.05). There was no significant difference in the incidence of urinary tract infection and urinary retention between the two groups (P> 0.05). The incidence of postoperative hematuria (including microscopic hematuria) was significant in two groups（P< 0.05). Ureteric injury occurred in the 9 patients in the control group (11.25%).\u0000Conclusion: Ureteral catheter inserted before radical operation of cervical cancer can help to identify the ureter easily, decrease urinary tract injury, shorten operation time and reduce intra-operative blood loss, and will not increase urinary retention and urinary tract infection. It is safe and effective method especially for young gynecologists.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126075464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C1q and tumor necrosis factor (TNF)-related proteins (CTRPs) are a superfamily of proteins secreted in adipose tissues that are highly homologous to lipocalin. Previous studies have shown that this family has important biological functions in diseases such as metabolic disorders, cardiovascular diseases and inflammation in many types of tissues. C1q-like protein 4 (C1ql4) is one of the members of this family, which is mainly expressed in the testis and adipose tissue, and plays an important role in promoting angiogenesis, regulating lipid synthesis, inducting testosterone secretion, inhibiting ovarian granulosa cell apoptosis and myoblast fusion. This article reviews the current progress on molecular structure, tissue expression, and the main biological functions of C1ql4.
{"title":"Progress in the understanding of C1q-like protein 4 (C1ql4) and its use in oncology","authors":"Z. Qing, Li Qing-shan, Han Wan-Yue, Xu Fan","doi":"10.3126/njc.v6i1.44203","DOIUrl":"https://doi.org/10.3126/njc.v6i1.44203","url":null,"abstract":"C1q and tumor necrosis factor (TNF)-related proteins (CTRPs) are a superfamily of proteins secreted in adipose tissues that are highly homologous to lipocalin. Previous studies have shown that this family has important biological functions in diseases such as metabolic disorders, cardiovascular diseases and inflammation in many types of tissues. C1q-like protein 4 (C1ql4) is one of the members of this family, which is mainly expressed in the testis and adipose tissue, and plays an important role in promoting angiogenesis, regulating lipid synthesis, inducting testosterone secretion, inhibiting ovarian granulosa cell apoptosis and myoblast fusion. This article reviews the current progress on molecular structure, tissue expression, and the main biological functions of C1ql4.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132551478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Sapkota, D. K. Mallik, Bhawna Wagle, Sunil Dhakal, Sapana Bhandari
Background: Carcinoma stomach is a multifactorial disease accounting for second most common cancer among male and fifth most common cancer among Nepalese population. The prevalence of stomach cancer is partially influenced by geographical variation, social and cultural factors that significantly affect disease reporting and seeking medical care. In this study we have analyzed geographical trends in prevalence of stomach cancer among patients visiting BPKMCH. Materials and Methods: A single center descriptive retrospective study to analyze the geographical trends among stomach cancer patients visiting BPKMCH from January 2013 to December 2017 was designed and patients’ information available at medical record were obtained. Analysis was completed with SPSS Statistics. Results: During the period of 5-year total 832 cases of stomach cancer were seen at the Department of Surgical Oncology at BPKMCH. These cases comprised of 349 female and 483 males with male to female (M: F) ratio of 1.4:1. The mean age of presentation was 55 years. Maximum number of cases 57.3% (477) were from terai region of Nepal. Conclusions: This study provides clue regarding higher cases of stomach cancer among male patients and from terai region of Nepal.
{"title":"Geographical Trends in Prevalence of Stomach Cancer in Nepal","authors":"G. Sapkota, D. K. Mallik, Bhawna Wagle, Sunil Dhakal, Sapana Bhandari","doi":"10.3126/njc.v6i1.44254","DOIUrl":"https://doi.org/10.3126/njc.v6i1.44254","url":null,"abstract":"Background: Carcinoma stomach is a multifactorial disease accounting for second most common cancer among male and fifth most common cancer among Nepalese population. The prevalence of stomach cancer is partially influenced by geographical variation, social and cultural factors that significantly affect disease reporting and seeking medical care. In this study we have analyzed geographical trends in prevalence of stomach cancer among patients visiting BPKMCH. \u0000Materials and Methods: A single center descriptive retrospective study to analyze the geographical trends among stomach cancer patients visiting BPKMCH from January 2013 to December 2017 was designed and patients’ information available at medical record were obtained. Analysis was completed with SPSS Statistics. \u0000Results: During the period of 5-year total 832 cases of stomach cancer were seen at the Department of Surgical Oncology at BPKMCH. These cases comprised of 349 female and 483 males with male to female (M: F) ratio of 1.4:1. The mean age of presentation was 55 years. Maximum number of cases 57.3% (477) were from terai region of Nepal. \u0000Conclusions: This study provides clue regarding higher cases of stomach cancer among male patients and from terai region of Nepal. \u0000 ","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125900843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Devkota, B. Thakur, Puroshattam Adhikari, Yogesh Regmi
Introduction: Anastomotic leak after esophagectomy for cancer of mid and lower esophagus and gastroesophageal junction (GEJ) still remains a major challenge. Poor perfusion of the gastric conduit remains the main factor for leak. Intra-operative assessment of the gastric conduit with indocyanine green (ICG) angiography helps to select a properly perfused site for anastomosis, thus minimizing the leak. Methods: Patients undergoing surgery for cancer of esophagus and GEJ either through open or minimally approach were taken up for this study. Stomach was used for reconstruction and anastomosis was made in neck. A 0.1ml of test dose of ICG was given intra-dermally to look for any reaction. After that a dose of 5-10 milligrams was injected intravenously. Perfusion was assessed with infrared light using laparoscopic telescope. The timing of perfusion of the conduit was recorded. Well perfused segment was used for gastroesophageal anastomosis. Different parameters including leak were compared with non-ICG group. Results: We studied 474 patients. Among these patients 67 were in ICG group and 407 were in non-ICG group. Mean age, mean weight loss and co-morbidities were similar in both groups. 72% of patients in ICG group and 50% of patient in non-ICG groups had multimodality treatment. 67% of patients in ICG group and 46% of patients in non-ICG group underwent minimally invasive surgery (p<0.001). Post-operative complications like pneumonia, recurrent laryngeal nerve palsy and surgical site infection were similar in both groups. Post-operative mortality was seen in 1.5% and 3.7% in ICG group and non-ICG group respectively (p=0.4). Overall leak in ICG group was 9% and 16.5% in non-ICG group (p=0.06). In ICG group with the perfusion time of more than 60 seconds, the leak rate was only 3.5% in comparison to 16.5% in non ICG group (p=0.009). Conclusion: ICG angiography provides an objective assessment about the perfusion of gastric conduit during the time of anastomosis. Anastomosis at area of gastric conduit with perfusion time less than 60 seconds, minimizes leak rate in neck.
{"title":"Use of Indocyanine green (ICG) angiography to minimize anastomotic leak in the neck after esophagectomy","authors":"M. Devkota, B. Thakur, Puroshattam Adhikari, Yogesh Regmi","doi":"10.3126/njc.v6i1.44212","DOIUrl":"https://doi.org/10.3126/njc.v6i1.44212","url":null,"abstract":"Introduction: Anastomotic leak after esophagectomy for cancer of mid and lower esophagus and gastroesophageal junction (GEJ) still remains a major challenge. Poor perfusion of the gastric conduit remains the main factor for leak. Intra-operative assessment of the gastric conduit with indocyanine green (ICG) angiography helps to select a properly perfused site for anastomosis, thus minimizing the leak.\u0000Methods: Patients undergoing surgery for cancer of esophagus and GEJ either through open or minimally approach were taken up for this study. Stomach was used for reconstruction and anastomosis was made in neck. A 0.1ml of test dose of ICG was given intra-dermally to look for any reaction. After that a dose of 5-10 milligrams was injected intravenously. Perfusion was assessed with infrared light using laparoscopic telescope. The timing of perfusion of the conduit was recorded. Well perfused segment was used for gastroesophageal anastomosis. Different parameters including leak were compared with non-ICG group.\u0000Results: We studied 474 patients. Among these patients 67 were in ICG group and 407 were in non-ICG group. Mean age, mean weight loss and co-morbidities were similar in both groups. 72% of patients in ICG group and 50% of patient in non-ICG groups had multimodality treatment. 67% of patients in ICG group and 46% of patients in non-ICG group underwent minimally invasive surgery (p<0.001). Post-operative complications like pneumonia, recurrent laryngeal nerve palsy and surgical site infection were similar in both groups. Post-operative mortality was seen in 1.5% and 3.7% in ICG group and non-ICG group respectively (p=0.4). Overall leak in ICG group was 9% and 16.5% in non-ICG group (p=0.06). In ICG group with the perfusion time of more than 60 seconds, the leak rate was only 3.5% in comparison to 16.5% in non ICG group (p=0.009).\u0000Conclusion: ICG angiography provides an objective assessment about the perfusion of gastric conduit during the time of anastomosis. Anastomosis at area of gastric conduit with perfusion time less than 60 seconds, minimizes leak rate in neck.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127970857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: The aim of the study is to report early experience in ultrasound guided central chemo port insertion by surgeons in cancer patients who required chemotherapy. Materials and methods: The procedure was carried out in operation theatre under local anesthesia with intravenous sedation. Linear high frequency ultrasound probe was used to visualize and cannulate left or right internal jugular vein in the neck. The reservoir was kept through a separate incision over anterior chest wall. Results: Fifty patients with mean age of 48 years underwent chemo port insertion. The indications were neoadjuvant, adjuvant and palliative chemotherapy in 30%, 58% and 12%, respectively. Cannulation was successful in 100% of cases. Two patients (4%) required port removal due to wound infection (one patient) and blockade (one patient). One patient (2%) had kinking of the catheter which required repositioning. Conclusion: Ultrasound guided central chemo port insertion by surgeons is a safe procedure with 100% success rate and minimal complications.
{"title":"Ultrasound Guided Central Chemotherapy Port Insertion by Surgeon in Cancer Patients.","authors":"M. Devkota, B. Thakur, M. Chaudhary","doi":"10.3126/njc.v6i1.44200","DOIUrl":"https://doi.org/10.3126/njc.v6i1.44200","url":null,"abstract":"Purpose: The aim of the study is to report early experience in ultrasound guided central chemo port insertion by surgeons in cancer patients who required chemotherapy.\u0000Materials and methods: The procedure was carried out in operation theatre under local anesthesia with intravenous sedation. Linear high frequency ultrasound probe was used to visualize and cannulate left or right internal jugular vein in the neck. The reservoir was kept through a separate incision over anterior chest wall.\u0000Results: Fifty patients with mean age of 48 years underwent chemo port insertion. The indications were neoadjuvant, adjuvant and palliative chemotherapy in 30%, 58% and 12%, respectively. Cannulation was successful in 100% of cases. Two patients (4%) required port removal due to wound infection (one patient) and blockade (one patient). One patient (2%) had kinking of the catheter which required repositioning.\u0000Conclusion: Ultrasound guided central chemo port insertion by surgeons is a safe procedure with 100% success rate and minimal complications.\u0000 \u0000 ","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131616999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bronchogenic cysts are rare cystic disease of the mediastinum in children. They are often asymptomatic and are diagnosed incidentally. Symptoms, if present are due to compression of the adjacent structures or the added infection. A 5 year old female child was referred to our thoracic surgery department with history of fever for 2 days. She had recurrent respiratory tract infection in the past needing treatment. CT revealed a cystic mass in the mediastinum. Video Assisted Thoracoscopic Surgery (VATS) excision of the cyst was done. The patient recovered uneventfully and the histopathological examination revealed it to be a bronchogenic cyst.
{"title":"Bronchogenic Cyst in a young Child","authors":"Niraj Bhattarai, Rasesh Shrestha, B. Thakur","doi":"10.3126/njc.v6i1.44202","DOIUrl":"https://doi.org/10.3126/njc.v6i1.44202","url":null,"abstract":"Bronchogenic cysts are rare cystic disease of the mediastinum in children. They are often asymptomatic and are diagnosed incidentally. Symptoms, if present are due to compression of the adjacent structures or the added infection. A 5 year old female child was referred to our thoracic surgery department with history of fever for 2 days. She had recurrent respiratory tract infection in the past needing treatment. CT revealed a cystic mass in the mediastinum. Video Assisted Thoracoscopic Surgery (VATS) excision of the cyst was done. The patient recovered uneventfully and the histopathological examination revealed it to be a bronchogenic cyst.","PeriodicalId":133249,"journal":{"name":"Nepalese Journal of Cancer","volume":"265 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114330261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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