Pub Date : 2018-01-01DOI: 10.14303/IMAGING-MEDICINE.1000116
Nguyen Minh Duc Huynh Quang Huy
High-intensity focused ultrasound (HIFU) treatment for prostate cancer and benign prostatic hyperplasia (BPH) was utilized worldwide owing to benefits of non-invasive treatment, fast recovery time, and low rate of complications. There are many approaches of HIFU for BPH and prostate cancer under the guidance of real-time magnetic resonance imaging or ultrasound and the location of treatment transducer inside the rectum or urethra. In this article, we aimed to introduce these approaches for clinicians to consider as an alternative treatment option.
{"title":"A Technical Update Of High-intensity Focused Ultrasound Ablation For Prostate Cancer And Benign Prostatic Hyperplasia","authors":"Nguyen Minh Duc Huynh Quang Huy","doi":"10.14303/IMAGING-MEDICINE.1000116","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000116","url":null,"abstract":"High-intensity focused ultrasound (HIFU) treatment for prostate cancer and benign prostatic hyperplasia (BPH) was utilized worldwide owing to benefits of non-invasive treatment, fast recovery time, and low rate of complications. There are many approaches of HIFU for BPH and prostate cancer under the guidance of real-time magnetic resonance imaging or ultrasound and the location of treatment transducer inside the rectum or urethra. In this article, we aimed to introduce these approaches for clinicians to consider as an alternative treatment option.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"167 1","pages":"139-142"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80496443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/IMAGING-MEDICINE.1000121
C. Lauridsen, Thomas Axelsen, M. Hansen, E. Fallentin, M. Nielsen, R. Eefsen, M. Illemann, L. Engelholm, B. Vainer, G. Høyer-Hansen, I. Lund, G. Willemoe, H. Rolff, M. Osterlind
Background: Dynamic contrast-enhanced computed tomography (DCE-CT) is a promising non-invasive method that provides the functional evaluation of the vascularity in normal and malignant tissue. The objectives of this consecutive study were to investigate the possible correlation between the perfusion characteristics of colorectal cancer liver metastases as examined by (DCE-CT) and the microvessel density of resected metastases. An additional aim was to investigate the correlation between the urokinase plasminogen activation receptor (uPAR) and perfusion values. Methods and findings: Eleven patients fulfilled the criteria for comparative analyses. The microvessel density values,uPAR level and the DCE-CT values were analysed. A perfusion index (PI) based on the measurement of arterial and portal flow (AF, PF) was defined as follows: PI=AF/ (AF+PF)%. The DCE-CT measurements were compared between metastatic and normal liver tissues. A Spearman correlation test was used for statistical analysis. The perfusion index and microvessel density values were significantly correlated (r=0.75; p=0.01). Furthermore, a higher volume of metastases significantly correlated with higher plasma levels of the uPAR forms (0.72 ≤ r ≥ 0.89; p < 0.05). Conclusions: DCE-CT may have the potential to measure the vascularity of colorectal liver metastases; however, the correlation between microvessel density and the perfusion values appears vague.
{"title":"Assessment Of The Correlation Between Dynamic Contrast Enhanced Computed Tomography And Histological And Vascular Biomarkers In Patients Resected For Colorectal Liver Metastases","authors":"C. Lauridsen, Thomas Axelsen, M. Hansen, E. Fallentin, M. Nielsen, R. Eefsen, M. Illemann, L. Engelholm, B. Vainer, G. Høyer-Hansen, I. Lund, G. Willemoe, H. Rolff, M. Osterlind","doi":"10.14303/IMAGING-MEDICINE.1000121","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000121","url":null,"abstract":"Background: Dynamic contrast-enhanced computed tomography (DCE-CT) is a promising non-invasive method that provides the functional evaluation of the vascularity in normal and malignant tissue. The objectives of this consecutive study were to investigate the possible correlation between the perfusion characteristics of colorectal cancer liver metastases as examined by (DCE-CT) and the microvessel density of resected metastases. An additional aim was to investigate the correlation between the urokinase plasminogen activation receptor (uPAR) and perfusion values. Methods and findings: Eleven patients fulfilled the criteria for comparative analyses. The microvessel density values,uPAR level and the DCE-CT values were analysed. A perfusion index (PI) based on the measurement of arterial and portal flow (AF, PF) was defined as follows: PI=AF/ (AF+PF)%. The DCE-CT measurements were compared between metastatic and normal liver tissues. A Spearman correlation test was used for statistical analysis. The perfusion index and microvessel density values were significantly correlated (r=0.75; p=0.01). Furthermore, a higher volume of metastases significantly correlated with higher plasma levels of the uPAR forms (0.72 ≤ r ≥ 0.89; p < 0.05). Conclusions: DCE-CT may have the potential to measure the vascularity of colorectal liver metastases; however, the correlation between microvessel density and the perfusion values appears vague.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"1 1","pages":"147-154"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76938047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/imaging-medicine.1000125
Sindhu P Kumar
{"title":"Imaging characteristics of mature cystic teratoma","authors":"Sindhu P Kumar","doi":"10.14303/imaging-medicine.1000125","DOIUrl":"https://doi.org/10.14303/imaging-medicine.1000125","url":null,"abstract":"","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"64 1","pages":"15-16"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84579890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/imaging-medicine.1000100
Yavuz Yuksel, O. Gok
Background: Gallbladder perforation secondary to cholecystitis are rarely seen. Gallbladder perforation is associated with intra or extra-hepatic abscesses and peritonitis and is high mortality rates. We report a case of gallbladder perforation. Case presentation: An 80 year old male patient was admitted to our hospital with abdominal pain. The aspartate aminotransferase, alanine aminotransferase and C-reactive protein values of the patient were high. The patient underwent intravenous contrast-enhanced abdominal computed tomography. Abdominal computed tomography showed a hydropic gallbladder, loculated fluid collections surrounding the liver and an increase in the gallbladder wall thickness. There was also defect in fundus of the gallbladder. The patient was operated based on clinical and radiological findings. Operative findings confirmed preoperative radiological findings. Conclusion: Gallbladder perforation is rare but in such cases early diagnosis is of vital importance. Ultrasonography and computed tomography are the imaging modalities for the diagnosis of gallbladder perforation.
{"title":"A rare complication of acute cholecystitis leading to perihepatic abscess: gall bladder perforation","authors":"Yavuz Yuksel, O. Gok","doi":"10.14303/imaging-medicine.1000100","DOIUrl":"https://doi.org/10.14303/imaging-medicine.1000100","url":null,"abstract":"Background: Gallbladder perforation secondary to cholecystitis are rarely seen. Gallbladder perforation is associated with intra or extra-hepatic abscesses and peritonitis and is high mortality rates. We report a case of gallbladder perforation. Case presentation: An 80 year old male patient was admitted to our hospital with abdominal pain. The aspartate aminotransferase, alanine aminotransferase and C-reactive protein values of the patient were high. The patient underwent intravenous contrast-enhanced abdominal computed tomography. Abdominal computed tomography showed a hydropic gallbladder, loculated fluid collections surrounding the liver and an increase in the gallbladder wall thickness. There was also defect in fundus of the gallbladder. The patient was operated based on clinical and radiological findings. Operative findings confirmed preoperative radiological findings. Conclusion: Gallbladder perforation is rare but in such cases early diagnosis is of vital importance. Ultrasonography and computed tomography are the imaging modalities for the diagnosis of gallbladder perforation.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"27 1","pages":"47-49"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88918551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/imaging-medicine.1000097
Nguyen Huy
Appearance of bowel loops in the sonication beam path during high-intensity focused ultrasound (HIFU) ablation therapy is a problematic condition. Filling bladder, filling rectum and, emptying bladder (BRB) maneuver technique might be helpful in producing a non-bowel treatment window for HIFU ablation of uterine fibroids and adenomyosis and ensuring the safety profile for patients.
{"title":"High-intensity focused ultrasound of uterine fibroids and adenomyosis: maneuver technique for bowel loops located inside the treatment window","authors":"Nguyen Huy","doi":"10.14303/imaging-medicine.1000097","DOIUrl":"https://doi.org/10.14303/imaging-medicine.1000097","url":null,"abstract":"Appearance of bowel loops in the sonication beam path during high-intensity focused ultrasound (HIFU) ablation therapy is a problematic condition. Filling bladder, filling rectum and, emptying bladder (BRB) maneuver technique might be helpful in producing a non-bowel treatment window for HIFU ablation of uterine fibroids and adenomyosis and ensuring the safety profile for patients.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"22 1","pages":"29-31"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74878101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/Imaging-Medicine.1000091
Z. Alaya, Mouna Braham, E. Bouajina
Background: Extra-articular manifestations in rheumatoid arthritis (RA) are rare and generally occur in an advanced stage of the disease. We report a case of an unusual onset of early RA. Case presentation: A 21 year old male complains of polyathritis involving small and large joints, associated with fever, asthenia, anorexia and weight loss. The temperature was up to 38.8°. There was a left cervical adenopathies, hepato-splenomegaly and there were synovitis in all joints sparing distal interphalangial joints. The erythrocyte sedimentation rate was accelerated; the C-reactive protein was up to 222 mg/l. The number of white blood cells were 9000/mm3 with monocytosis, lymphocytosis and thrombocytosis at 986000/mm3 . There was cholestasis with cytolysis. Rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibodies (ACCP) were positive. The hands X-ray didn’t show any RA specific signs. The chest X-Ray showed a left pleurisy. The CT scan showed multiple axillar and mediastinal lymphadenopathies, hepato-splenomegaly with multiple coelio-mesenteric and retroperitoneal lymph nodes. The pleural biopsy as well as the biopsy of the adenopathy and the salivary glands didn’t show any specific abnormalities or signs of lymphoma. The hepatic biopsy revealed an inflammatory lymphohistiocytic infiltrate with rare foci of necrosis and a dilatation of the hepatic sinusoids. The diagnosis of RA was suspected and confirmed by the MRI of the hands. Conclusion: RA may have an unusual onset such as hematologic, hepatic, pleuropulmonary features or tumor syndrome, but it is rarely reported. The diagnosis in this case is difficult
{"title":"Tumor syndrome, hepatic and hematological features revealing undiagnosed early rheumatoid arthritis","authors":"Z. Alaya, Mouna Braham, E. Bouajina","doi":"10.14303/Imaging-Medicine.1000091","DOIUrl":"https://doi.org/10.14303/Imaging-Medicine.1000091","url":null,"abstract":"Background: Extra-articular manifestations in rheumatoid arthritis (RA) are rare and generally occur in an advanced stage of the disease. We report a case of an unusual onset of early RA. Case presentation: A 21 year old male complains of polyathritis involving small and large joints, associated with fever, asthenia, anorexia and weight loss. The temperature was up to 38.8°. There was a left cervical adenopathies, hepato-splenomegaly and there were synovitis in all joints sparing distal interphalangial joints. The erythrocyte sedimentation rate was accelerated; the C-reactive protein was up to 222 mg/l. The number of white blood cells were 9000/mm3 with monocytosis, lymphocytosis and thrombocytosis at 986000/mm3 . There was cholestasis with cytolysis. Rheumatoid factor (RF) and anti-cyclic citrullinated peptide antibodies (ACCP) were positive. The hands X-ray didn’t show any RA specific signs. The chest X-Ray showed a left pleurisy. The CT scan showed multiple axillar and mediastinal lymphadenopathies, hepato-splenomegaly with multiple coelio-mesenteric and retroperitoneal lymph nodes. The pleural biopsy as well as the biopsy of the adenopathy and the salivary glands didn’t show any specific abnormalities or signs of lymphoma. The hepatic biopsy revealed an inflammatory lymphohistiocytic infiltrate with rare foci of necrosis and a dilatation of the hepatic sinusoids. The diagnosis of RA was suspected and confirmed by the MRI of the hands. Conclusion: RA may have an unusual onset such as hematologic, hepatic, pleuropulmonary features or tumor syndrome, but it is rarely reported. The diagnosis in this case is difficult","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"5 1","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90107891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/imaging-medicine.1000109
Ramya Ch, B. Ra, aru N Rachegowda
Purpose: To evaluate USG and CT imaging findings in differentiating transudative and exudative pleural effusion. Materials and methods: A prospective observational study was performed over a period of eighteen months between January 2016 and June 2017. Eighty patients with pleural effusion were included and were evaluated with USG and CT along with diagnostic thoracocentesis. USG appearances and CT attenuation values along with additional findings like presence of pleural thickening, pleural nodules and loculation were evaluated. Results: 24 (30%) were transudates and 56 (70%) were exudates. Transudative were always anechoic. Exudates were complex septated (62.5%), echogenic (25%) or complex non-septated (8.9%) on USG with very few being anechoic (3.5%). Loculations were better appreciated on ultrasound while pleural thickening and nodules were better seen on CT. Mean attenuation values were significantly higher in exudates (14.65 ± 6.07; mean ± SD, range: 4.5 to 34) than transudates (4.66 ± 2.29; mean ± SD, range: 1.3 to 8.2) with a P value <0.01. Effusions can be considered as transudative if the CT attenuation value is <8, with a sensitivity of 91.6% and specificity of 82.7% with a significant P value <0.01. Pleural thickening, nodules and loculations were seen commonly in exudates than transudates with a high specificity (91.6 %, 95.8% and 100% respectively). Conclusion: USG is a helpful non-invasive and bedside tool in determining the nature of pleural effusion. CT attenuation values play a useful role in differentiating the nature of pleural effusion. Transudative effusions can be considered when HU values are <8.
{"title":"Efficacy Of ultrasonography and computed tomography in differentiating transudate from exudate in patients with pleural effusion","authors":"Ramya Ch, B. Ra, aru N Rachegowda","doi":"10.14303/imaging-medicine.1000109","DOIUrl":"https://doi.org/10.14303/imaging-medicine.1000109","url":null,"abstract":"Purpose: To evaluate USG and CT imaging findings in differentiating transudative and exudative pleural effusion. Materials and methods: A prospective observational study was performed over a period of eighteen months between January 2016 and June 2017. Eighty patients with pleural effusion were included and were evaluated with USG and CT along with diagnostic thoracocentesis. USG appearances and CT attenuation values along with additional findings like presence of pleural thickening, pleural nodules and loculation were evaluated. Results: 24 (30%) were transudates and 56 (70%) were exudates. Transudative were always anechoic. Exudates were complex septated (62.5%), echogenic (25%) or complex non-septated (8.9%) on USG with very few being anechoic (3.5%). Loculations were better appreciated on ultrasound while pleural thickening and nodules were better seen on CT. Mean attenuation values were significantly higher in exudates (14.65 ± 6.07; mean ± SD, range: 4.5 to 34) than transudates (4.66 ± 2.29; mean ± SD, range: 1.3 to 8.2) with a P value <0.01. Effusions can be considered as transudative if the CT attenuation value is <8, with a sensitivity of 91.6% and specificity of 82.7% with a significant P value <0.01. Pleural thickening, nodules and loculations were seen commonly in exudates than transudates with a high specificity (91.6 %, 95.8% and 100% respectively). Conclusion: USG is a helpful non-invasive and bedside tool in determining the nature of pleural effusion. CT attenuation values play a useful role in differentiating the nature of pleural effusion. Transudative effusions can be considered when HU values are <8.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"69 1","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79610198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/imaging-medicine.1000101
Ina Zhika
Introduction: Lung cancer is one of the most common and serious types of cancer. Cancer that begins in the lungs is called primary lung cancer. Cancer that spreads to the lungs from another place in the body is known as secondary lung cancer. There are two main types of primary lung cancer. These are classified by the type of cells in which the cancer starts. They are: 1. Non-small-cell lung cancer – the most common type, accounting for more than 80% of cases; can be squamous cell carcinoma, adenocarcinoma or large-cell carcinoma. 2. Small-cell lung cancer – a less common type that usually spreads faster than non-small-cell lung cancer. Imaging techniques used for the detection, characterisation, staging and follow-up of lung cancer are: • Conventional chest radiography, • Computed tomography (CT), • Magnetic resonance (MR), • Positron emission tomography (PET). Methods: This research is descriptive with retrospective components and the data are taken from the book of protocol of the people with Lung Cancer treated in the hospital Center “Xhaferr Kongoli” in the period time of 2013-2015. This study involved 47 patients. Results: From 47 patients 45 are males (96 %) and 2 are females (4%). From these 26 patients or 55% are from the city and 21 patients or 45% are from village. The most affected age is 55-64 years old with 26 patients (55%), over 65 years old with 14 patients (30%), 45-54 years old with 7 patients (15%). From 47 patients 30 are smokers (64%) and 17 patients are non-smokers (36%). Conclusion: Based on the date obtained from patients treated for lung cancer we conclude that: 1. The most frequently affected age group is 55-64 years old. 2. The most affected sex is male. 3. It is more spread in urban areas than rural ones. Lung cancer mainly affects smokers versus non-smokers.
{"title":"The cases treated with lung cancer in the hospital center xhaferr kongoli in the period time of 2013-2015","authors":"Ina Zhika","doi":"10.14303/imaging-medicine.1000101","DOIUrl":"https://doi.org/10.14303/imaging-medicine.1000101","url":null,"abstract":"Introduction: Lung cancer is one of the most common and serious types of cancer. Cancer that begins in the lungs is called primary lung cancer. Cancer that spreads to the lungs from another place in the body is known as secondary lung cancer. There are two main types of primary lung cancer. These are classified by the type of cells in which the cancer starts. They are: 1. Non-small-cell lung cancer – the most common type, accounting for more than 80% of cases; can be squamous cell carcinoma, adenocarcinoma or large-cell carcinoma. 2. Small-cell lung cancer – a less common type that usually spreads faster than non-small-cell lung cancer. Imaging techniques used for the detection, characterisation, staging and follow-up of lung cancer are: • Conventional chest radiography, • Computed tomography (CT), • Magnetic resonance (MR), • Positron emission tomography (PET). Methods: This research is descriptive with retrospective components and the data are taken from the book of protocol of the people with Lung Cancer treated in the hospital Center “Xhaferr Kongoli” in the period time of 2013-2015. This study involved 47 patients. Results: From 47 patients 45 are males (96 %) and 2 are females (4%). From these 26 patients or 55% are from the city and 21 patients or 45% are from village. The most affected age is 55-64 years old with 26 patients (55%), over 65 years old with 14 patients (30%), 45-54 years old with 7 patients (15%). From 47 patients 30 are smokers (64%) and 17 patients are non-smokers (36%). Conclusion: Based on the date obtained from patients treated for lung cancer we conclude that: 1. The most frequently affected age group is 55-64 years old. 2. The most affected sex is male. 3. It is more spread in urban areas than rural ones. Lung cancer mainly affects smokers versus non-smokers.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"22 1","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80116986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.14303/IMAGING-MEDICINE.1000106
A. Corti, H. Poteca, M. Garavaglia
The optical biopsy is a noninvasive diagnostic procedure that performs an analysis of the tissue with an optical system that allows reaching a result without extracting the sample (excisional biopsy) from the body tissue. Particularly, we are making spectrofluorometry (SFM) observations in loci lesions and healthy surrounding areas. The tissue is accessed through the body surface, including the analysis of the skin itself or mucosal surface, or by endoscope into any cavity. We have found spectral similarities in the detection of infectious diseases of their natural spectral fluorescence. Specifically, in the analyzed cases of DNA-HPV+ patients, we observed in all of their fluorescence spectra the same type of relevant peaks. So, we present here the SFM observation of HPV6 infected hard palate case. In addition, we show in this case the positive reaction images after the topication with 3-5% acetic acid as it occurs in the cervix uterine lesion.
{"title":"Case report: optical biopsy in HPV6 lesion","authors":"A. Corti, H. Poteca, M. Garavaglia","doi":"10.14303/IMAGING-MEDICINE.1000106","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000106","url":null,"abstract":"The optical biopsy is a noninvasive diagnostic procedure that performs an analysis of the tissue with an optical system that allows reaching a result without extracting the sample (excisional biopsy) from the body tissue. Particularly, we are making spectrofluorometry (SFM) observations in loci lesions and healthy surrounding areas. The tissue is accessed through the body surface, including the analysis of the skin itself or mucosal surface, or by endoscope into any cavity. We have found spectral similarities in the detection of infectious diseases of their natural spectral fluorescence. Specifically, in the analyzed cases of DNA-HPV+ patients, we observed in all of their fluorescence spectra the same type of relevant peaks. So, we present here the SFM observation of HPV6 infected hard palate case. In addition, we show in this case the positive reaction images after the topication with 3-5% acetic acid as it occurs in the cervix uterine lesion.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"1 1","pages":"85-87"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84179776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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