Pub Date : 2017-01-01DOI: 10.14303/IMAGING-MEDICINE.1000042
R. Asadov, T. Y. Kuzan, R. Ergelen, T. Demirbaş, Davut Tuney
A parastomal hernia is an incisional hernia related to an abdominal wall stoma. Parastomal hernia occurs frequently after the formation of a colostomy or ileostomy and it is the most common late stoma complication. Contents of parastomal hernia almost exclusively are limited to the mobile structures of the abdomen. Parastomal hernia including stomach is extremely rare. We describe a case of parastomal hernia containing stomach in a 65 year old woman who underwent rectal resection and left lower quadrant colostomy two years ago for rectal adenocarcinoma. The patient was presented to our emergency department with abdominal pain, vomiting and upper abdominal distension proceeding for 2 weeks. Abdominal CT revealed mild gastric dilatation associated with a parastomal hernia that contained the gastric corpus and antrum. The parastomal hernia was manually reduced. After 7 days, the patient fully recovered and was discharged. Parastomal hernia may contain stomach in patients presenting with obstructive symptoms. To the best of our knowledge, the current case has been published the ninth of such cases. Although rare, the present case is noteworthy in highlighting both the importance of being aware of this entity as well as radiologic confirmation to make correct diagnosis.
{"title":"Uncommon parastomal herniacontaining stomach: CT findings andreview of literature","authors":"R. Asadov, T. Y. Kuzan, R. Ergelen, T. Demirbaş, Davut Tuney","doi":"10.14303/IMAGING-MEDICINE.1000042","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000042","url":null,"abstract":"A parastomal hernia is an incisional hernia related to an abdominal wall stoma. Parastomal hernia occurs frequently after the formation of a colostomy or ileostomy and it is the most common late stoma complication. Contents of parastomal hernia almost exclusively are limited to the mobile structures of the abdomen. Parastomal hernia including stomach is extremely rare. We describe a case of parastomal hernia containing stomach in a 65 year old woman who underwent rectal resection and left lower quadrant colostomy two years ago for rectal adenocarcinoma. The patient was presented to our emergency department with abdominal pain, vomiting and upper abdominal distension proceeding for 2 weeks. Abdominal CT revealed mild gastric dilatation associated with a parastomal hernia that contained the gastric corpus and antrum. The parastomal hernia was manually reduced. After 7 days, the patient fully recovered and was discharged. Parastomal hernia may contain stomach in patients presenting with obstructive symptoms. To the best of our knowledge, the current case has been published the ninth of such cases. Although rare, the present case is noteworthy in highlighting both the importance of being aware of this entity as well as radiologic confirmation to make correct diagnosis.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"8 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89407459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/Imaging-Medicine.1000041
Mudge Cs, M. Sd
A 13 year old boy with history of phosphaturic mesenchymal tumor of the proximal tibia, resected two years previously, developed biochemical evidence of recurrence. Radiographs and MRI of the resection site failed to identify the site of recurrence. 18FDG-PET/CT and 111In-Octreoscan were performed concurrently, and both identified a site of abnormal uptake adjacent to the resection margin in the proximal tibia. Phosphaturic mesenchymal tumor is a pediatric rare tumor associated with tumor-induced osteomalacia. This unique case demonstrates the utility of nuclear medicine imaging in localizing recurrence of an uncommon tumor, and the potential role of 18FDG-PET/CT in managing these patients.
{"title":"Localization of recurrent phosphaturic mesenchymal tumor in a child using 18FDG-PET/CT and 111In-Octreoscan","authors":"Mudge Cs, M. Sd","doi":"10.14303/Imaging-Medicine.1000041","DOIUrl":"https://doi.org/10.14303/Imaging-Medicine.1000041","url":null,"abstract":"A 13 year old boy with history of phosphaturic mesenchymal tumor of the proximal tibia, resected two years previously, developed biochemical evidence of recurrence. Radiographs and MRI of the resection site failed to identify the site of recurrence. 18FDG-PET/CT and 111In-Octreoscan were performed concurrently, and both identified a site of abnormal uptake adjacent to the resection margin in the proximal tibia. Phosphaturic mesenchymal tumor is a pediatric rare tumor associated with tumor-induced osteomalacia. This unique case demonstrates the utility of nuclear medicine imaging in localizing recurrence of an uncommon tumor, and the potential role of 18FDG-PET/CT in managing these patients.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"28 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77772858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/Imaging-Medicine.1000067
D. Koundal, Bhisham Sharma EktaG, Otra
Segmentation of images is one of the most challenging tasks because of restricted observation of the specialists and uncertainties presented in medical knowledge. Crisp values are inadequate to model real situation due to imprecise information frequently used in decision making process. Various intuitive methods have been explored to understand the ambiguity and uncertainty of medical images to carry out segmentation task. Therefore, in this paper, an attempt has been made to segment the medical images using clustering method based on Intuitionistic fuzzy set. With the incorporation of spatial information into intuitionistic clustering named as Spatial Intuitionistic Fuzzy C Means (SIFCM), the object of interest is segmented more accurately and effectively. The benefits of incorporating spatial information is that it is a powerful method for noisy image segmentation and works for both single and multiple-feature data with spatial information as well as capable of reduction of noisy spots and spurious blobs. The performances of proposed methods are evaluated for real images. The results indicate that SIFCM is more effective, and noise tolerant as compared with the fuzzy c-means clustering.
{"title":"Spatial intuitionistic fuzzy set basedimage segmentation","authors":"D. Koundal, Bhisham Sharma EktaG, Otra","doi":"10.14303/Imaging-Medicine.1000067","DOIUrl":"https://doi.org/10.14303/Imaging-Medicine.1000067","url":null,"abstract":"Segmentation of images is one of the most challenging tasks because of restricted observation of the specialists and uncertainties presented in medical knowledge. Crisp values are inadequate to model real situation due to imprecise information frequently used in decision making process. Various intuitive methods have been explored to understand the ambiguity and uncertainty of medical images to carry out segmentation task. Therefore, in this paper, an attempt has been made to segment the medical images using clustering method based on Intuitionistic fuzzy set. With the incorporation of spatial information into intuitionistic clustering named as Spatial Intuitionistic Fuzzy C Means (SIFCM), the object of interest is segmented more accurately and effectively. The benefits of incorporating spatial information is that it is a powerful method for noisy image segmentation and works for both single and multiple-feature data with spatial information as well as capable of reduction of noisy spots and spurious blobs. The performances of proposed methods are evaluated for real images. The results indicate that SIFCM is more effective, and noise tolerant as compared with the fuzzy c-means clustering.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"47 1","pages":"95-101"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80802220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/IMAGING-MEDICINE.1000045
L. Nissim, Conrad. Braun
Traumatic pseudoaneurysms of the visceral arteries are a rare but described entity. Typically, these are associated with penetrating trauma to the torso. They may present as a diagnostic challenge, as detection on conventional CT angiography is limited in the absence of surrounding hematoma or evidence for soft tissue or visceral organ injury. Clinically, this form of injury may present in both acute and delayed fashions. Post-traumatic pseudoaneurym of the left gastric artery is a seldom-described entity, particularly when encountered after blunt trauma. Here we present a young patient who sustained extensive injury after motor vehicle accident, with hemorrhagic shock on ER admission. Pseudoaneurysm with active bleeding from the left gastric artery was promptly detected on CT and immediately treated by angiographic embolization. A discussion of the available literature follows the case report.
{"title":"Embolization of left gastric artery pseudoaneurysm after blunt trauma","authors":"L. Nissim, Conrad. Braun","doi":"10.14303/IMAGING-MEDICINE.1000045","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000045","url":null,"abstract":"Traumatic pseudoaneurysms of the visceral arteries are a rare but described entity. Typically, these are associated with penetrating trauma to the torso. They may present as a diagnostic challenge, as detection on conventional CT angiography is limited in the absence of surrounding hematoma or evidence for soft tissue or visceral organ injury. Clinically, this form of injury may present in both acute and delayed fashions. Post-traumatic pseudoaneurym of the left gastric artery is a seldom-described entity, particularly when encountered after blunt trauma. Here we present a young patient who sustained extensive injury after motor vehicle accident, with hemorrhagic shock on ER admission. Pseudoaneurysm with active bleeding from the left gastric artery was promptly detected on CT and immediately treated by angiographic embolization. A discussion of the available literature follows the case report.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"8 1","pages":"15-17"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86213211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/Imaging-Medicine.1000077
Bonne Lee
A 36 year old woman presented with a 1 year history of nasal obstruction, exertional dyspnea with biphasic stridor and 10 kg unintentional weight loss. Laboratory investigations revealed that her hemoglobin level was 8.1 g/ dL and erythrocyte sedimentation rate was 41 mmph. Her anti-neutrophil cytoplasmic antibodies were positive. Chest radiograph revealed a small faint patch over left upper lung. Sinoscopy revealed a roomy nasal cavity caused by atrophy of the mucosa, thick discharge, lots of dark yellow crusts, epistaxis and a large perforation of the nasal septum. These findings suggested atrophic rhinitis complicated with perforation of the nasal septum (FIGURE 1 arrows: perforation of the nasal septum, asterisk: atrophy of the inferior turbinate). Bronchoscopy revealed approximately 80% stenosis of the subglottis (grade III, Cotton-Myer grading system) (FIGURE 2 arrows) and long-segmental subglottic granulomatous masses involving the glottis (stage IV, McCaffrey classification system) (FIGURE 3 arrow). An impending life-threatening subglottic stenosis was noted. Therefore, the patient underwent ventilation bronchoscopy and laryngotracheal reconstruction
{"title":"Subglottic stenosis in granulomatosis with polyangiitis (Wegener granulomatosis)","authors":"Bonne Lee","doi":"10.14303/Imaging-Medicine.1000077","DOIUrl":"https://doi.org/10.14303/Imaging-Medicine.1000077","url":null,"abstract":"A 36 year old woman presented with a 1 year history of nasal obstruction, exertional dyspnea with biphasic stridor and 10 kg unintentional weight loss. Laboratory investigations revealed that her hemoglobin level was 8.1 g/ dL and erythrocyte sedimentation rate was 41 mmph. Her anti-neutrophil cytoplasmic antibodies were positive. Chest radiograph revealed a small faint patch over left upper lung. Sinoscopy revealed a roomy nasal cavity caused by atrophy of the mucosa, thick discharge, lots of dark yellow crusts, epistaxis and a large perforation of the nasal septum. These findings suggested atrophic rhinitis complicated with perforation of the nasal septum (FIGURE 1 arrows: perforation of the nasal septum, asterisk: atrophy of the inferior turbinate). Bronchoscopy revealed approximately 80% stenosis of the subglottis (grade III, Cotton-Myer grading system) (FIGURE 2 arrows) and long-segmental subglottic granulomatous masses involving the glottis (stage IV, McCaffrey classification system) (FIGURE 3 arrow). An impending life-threatening subglottic stenosis was noted. Therefore, the patient underwent ventilation bronchoscopy and laryngotracheal reconstruction","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"2004 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86261155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/IMAGING-MEDICINE.1000043
Puneeth Shridhar, G. Eles, D. Lasorda, Youngjae Chun
Renal artery stenosis is a major cause of secondary hypertension. Bilateral non-atherosclerotic non-dysplastic renal artery stenosis can be seen following compression of the renal arteries by diaphragmatic crura/median arcuate ligament or external masses or fibrous bands. Never before, dynamic bilateral proximal stenosis, a new entity has been reported. The treatment is unknown. The learning point is that the patients undergoing angiographic screening for renovascular hypertension should undergo ‘breath in breath out’ test in order to visualize renal artery motion.
{"title":"Dynamic renal artery stenosis: Anincidental angiographic diagnosis or isthere more to it than meets the eye?","authors":"Puneeth Shridhar, G. Eles, D. Lasorda, Youngjae Chun","doi":"10.14303/IMAGING-MEDICINE.1000043","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000043","url":null,"abstract":"Renal artery stenosis is a major cause of secondary hypertension. Bilateral non-atherosclerotic non-dysplastic renal artery stenosis can be seen following compression of the renal arteries by diaphragmatic crura/median arcuate ligament or external masses or fibrous bands. Never before, dynamic bilateral proximal stenosis, a new entity has been reported. The treatment is unknown. The learning point is that the patients undergoing angiographic screening for renovascular hypertension should undergo ‘breath in breath out’ test in order to visualize renal artery motion.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"1 1","pages":"9-10"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79018696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/IMAGING-MEDICINE.1000078
N. Fukumitsu, T. Terunuma, T. Okumura, H. Numajiri, K. Murofushi, K. Ohnishi, M. Mizumoto, T. Aihara, H. Ishikawa, Koji Tsuboi Hideyuki Sakurai
Objective: To identify the previously irradiated region is important in re-irradiation. We investigated the long-term transition of geometrical accuracy of a commercially available rigid and deformable image registration (RIR, DIR) software product, MIM Maestro, in livers of patients who underwent proton beam therapy (PBT). Methods: Image registration of pre-treatment and post-treatment CT was performed in 15 liver tumor patients who received PBT and follow up post-treatment CT examination was performed over time (2-7 times each, a total of 54 times). We performed RIR and DIR of pre-treatment CT and compared the post-treatment CT by calculating the similarity of whole liver (Dice similarity coefficient: DSC) and dislocation of metallic markers implanted close to the tumor (fiducial registration error). Results: In the plain CT, the DSC was bigger with RIR in 1 case and DIR in 53 cases (0.83 ± 0.07 vs. 0.92 ± 0.04), then consistently bigger with DIR in 14 patients. The fiducial registration error was smaller with RIR in 10 cases, DIR in 43 cases, and equal error in 1 case (11.8 ± 6.9 vs. 7.6 ± 9.7 mm), then consistently smaller with DIR in 10 patients. In the contrast-enhanced CT, the DSC was consistently bigger with DIR in all 15 patients, 54 cases in all (0.84 ± 0.06 vs. 0.92 ± 0.03). The fiducial registration error was smaller with RIR in 7 cases and DIR in 47 cases (11.0 ± 6.3 vs. 6.3 ± 7.3 mm), then consistently smaller with DIR in 12 patients. Conclusion: The DIR performance of MIM is therefore superior to that of RIR and its advantage is independent the term after PBT.
目的:明确前辐照区在再辐照中的重要作用。我们研究了商业上可用的刚性和可变形图像配准(RIR, DIR)软件产品MIM Maestro在接受质子束治疗(PBT)的患者肝脏中的几何精度的长期转变。方法:对15例肝肿瘤患者行PBT治疗前后CT图像配准，并随访治疗后CT检查(各2 ~ 7次，共54次)。我们对治疗前CT进行RIR和DIR，并通过计算全肝的相似度(Dice similarity coefficient: DSC)和靠近肿瘤植入的金属标记物的错位度(基准点配准误差)来比较治疗后CT。结果:CT平扫中，1例DSC随RIR增大，53例DSC随DIR增大(0.83±0.07∶0.92±0.04)，14例DSC随DIR增大。10例RIR患者的基准登记误差较小，43例DIR患者的基准登记误差较小，1例误差相等(11.8±6.9 vs. 7.6±9.7 mm)， 10例DIR患者的基准登记误差一致较小。15例患者均有54例(0.84±0.06比0.92±0.03)，增强CT显示DSC均大于DIR。7例RIR和47例DIR的基准登记误差较小(11.0±6.3 vs. 6.3±7.3 mm)， 12例DIR的基准登记误差一致较小。结论:MIM的DIR性能优于RIR，且其优势在PBT后独立。
{"title":"Comparison of rigid and deformable image registration accuracy of the liver during long-term transition after proton beam therapy","authors":"N. Fukumitsu, T. Terunuma, T. Okumura, H. Numajiri, K. Murofushi, K. Ohnishi, M. Mizumoto, T. Aihara, H. Ishikawa, Koji Tsuboi Hideyuki Sakurai","doi":"10.14303/IMAGING-MEDICINE.1000078","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000078","url":null,"abstract":"Objective: To identify the previously irradiated region is important in re-irradiation. We investigated the long-term transition of geometrical accuracy of a commercially available rigid and deformable image registration (RIR, DIR) software product, MIM Maestro, in livers of patients who underwent proton beam therapy (PBT). Methods: Image registration of pre-treatment and post-treatment CT was performed in 15 liver tumor patients who received PBT and follow up post-treatment CT examination was performed over time (2-7 times each, a total of 54 times). We performed RIR and DIR of pre-treatment CT and compared the post-treatment CT by calculating the similarity of whole liver (Dice similarity coefficient: DSC) and dislocation of metallic markers implanted close to the tumor (fiducial registration error). Results: In the plain CT, the DSC was bigger with RIR in 1 case and DIR in 53 cases (0.83 ± 0.07 vs. 0.92 ± 0.04), then consistently bigger with DIR in 14 patients. The fiducial registration error was smaller with RIR in 10 cases, DIR in 43 cases, and equal error in 1 case (11.8 ± 6.9 vs. 7.6 ± 9.7 mm), then consistently smaller with DIR in 10 patients. In the contrast-enhanced CT, the DSC was consistently bigger with DIR in all 15 patients, 54 cases in all (0.84 ± 0.06 vs. 0.92 ± 0.03). The fiducial registration error was smaller with RIR in 7 cases and DIR in 47 cases (11.0 ± 6.3 vs. 6.3 ± 7.3 mm), then consistently smaller with DIR in 12 patients. Conclusion: The DIR performance of MIM is therefore superior to that of RIR and its advantage is independent the term after PBT.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"16 1","pages":"149-154"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86858641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/IMAGING-MEDICINE.1000075
A. Sugitachi, K. Otsuka, F. Endo, Toshimoto Kimura, T. Takahara, Y. Akiyama, T. Iwaya, H. Nitta, K. Koeda, Masaru Mizuno Akira Sasaki
Nerve-preservation technique plays an important role in surgery. Intraoperative nerve injuries often cause permanent neurogenic untoward events such as functional disorders, palsy, pain and numbness. To avoid such accidents, we devised an intraoperative fluorescence-imaging of peripheral nerves as a contribution to navigation surgery. Myelin-targeting fluorescent agents; namely, amphotericin B and fluorescinisothyanate, were used as markers of nerves in this study since myelin was a main component of Schwann sheath in peripheral nerve. In in vitro, cultured Schwann cells were served as model of peripheral nerves. After treating Schwann cells with each fluorescent agent, we observed the fluorescence emitted in a dark room. Then, we carried out in vivo studies with rats following the results of in vitro data and assessed the clinical significance of our newly devised method. We could clearly observe specific florescence the Schwann cells radiated in in vitro and discriminated peripheral nerve fibres from surrounding tissues in in vivo. These results strongly suggested a clinical usefulness of intraoperative visualization of peripheral nerve fibres. Our novel method would promote intraoperative nerve- preservation.
{"title":"Intraoperative fluorescence-imaging of nerves - a contribution to navigation surgery","authors":"A. Sugitachi, K. Otsuka, F. Endo, Toshimoto Kimura, T. Takahara, Y. Akiyama, T. Iwaya, H. Nitta, K. Koeda, Masaru Mizuno Akira Sasaki","doi":"10.14303/IMAGING-MEDICINE.1000075","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000075","url":null,"abstract":"Nerve-preservation technique plays an important role in surgery. Intraoperative nerve injuries often cause permanent neurogenic untoward events such as functional disorders, palsy, pain and numbness. To avoid such accidents, we devised an intraoperative fluorescence-imaging of peripheral nerves as a contribution to navigation surgery. Myelin-targeting fluorescent agents; namely, amphotericin B and fluorescinisothyanate, were used as markers of nerves in this study since myelin was a main component of Schwann sheath in peripheral nerve. In in vitro, cultured Schwann cells were served as model of peripheral nerves. After treating Schwann cells with each fluorescent agent, we observed the fluorescence emitted in a dark room. Then, we carried out in vivo studies with rats following the results of in vitro data and assessed the clinical significance of our newly devised method. We could clearly observe specific florescence the Schwann cells radiated in in vitro and discriminated peripheral nerve fibres from surrounding tissues in in vivo. These results strongly suggested a clinical usefulness of intraoperative visualization of peripheral nerve fibres. Our novel method would promote intraoperative nerve- preservation.","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"1 1","pages":"143-148"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82058095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-01-01DOI: 10.14303/IMAGING-MEDICINE.1000081
Cristian Rincón-Guio, Ana M Gomez Jose D Charry
Traumatic brain injury (TBI) is a critical public health problem. It represents one of the most important medicalsurgical pathology worldwide. The occurrence indicate that this kind of injury cause a large number of deaths and impairments leading to permanent disabilities, that is why is necessary to triage the patient and identify the injury extension. Imaging has become a significant tool not only in the diagnosis of patients with TBI, but also as a patient outcome predictor. This review of literature provides evidence of the current state of TBI imaging as to what is considered to be the indications, benefits and limitations of computed tomography (CT).
{"title":"The role of computed tomography as a prognostic tool in traumatic brain trauma","authors":"Cristian Rincón-Guio, Ana M Gomez Jose D Charry","doi":"10.14303/IMAGING-MEDICINE.1000081","DOIUrl":"https://doi.org/10.14303/IMAGING-MEDICINE.1000081","url":null,"abstract":"Traumatic brain injury (TBI) is a critical public health problem. It represents one of the most important medicalsurgical pathology worldwide. The occurrence indicate that this kind of injury cause a large number of deaths and impairments leading to permanent disabilities, that is why is necessary to triage the patient and identify the injury extension. Imaging has become a significant tool not only in the diagnosis of patients with TBI, but also as a patient outcome predictor. This review of literature provides evidence of the current state of TBI imaging as to what is considered to be the indications, benefits and limitations of computed tomography (CT).","PeriodicalId":13333,"journal":{"name":"Imaging in Medicine","volume":"38 1","pages":"171-178"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82241885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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