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An observational study on the effect of individualised homoeopathic medicine administered based on totality of symptoms vis-à-vis personality in cases of osteoarthritis knee 一项观察性研究,针对骨性膝关节炎患者,基于总体症状与-à-vis人格的个体化顺势疗法药物治疗效果
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_86_19
NHarihara Iyer, NRajeev Kumar
Background: Individualisation is the process of arriving at the image of the patient for the selection of remedy. The customary way of individualisation of the patient is through the construction of totality of symptoms. The little explored area in Homoeopathy is individualisation solely based on personality characteristics. Objective: The objective of this study was to compare the effect of individualised homoeopathic medicine administered based on totality of symptoms vis-à-vis personality in patients suffering from knee osteoarthritis. Methods: The observational study includes 60 clinically diagnosed cases of osteoarthritis knee, of which 30 cases were administered the homoeopathic medicine selected on the basis of totality of symptoms and thirty cases based on personality. Randomisation was done using computer-generated numbers. The personality of the patients was assessed through the 44-item Big-Five Inventory. A self-made tool, transcribing trait items to rubrics of the homoeopathic repertory, was prepared. The knee osteoarthritis scores on physical function, pain and patient global estimate in Routine Assessment of Patient Index Data 3 (RAPID3) sheet, before and after treatment, were compared. Results: The paired difference mean of RAPID3 in totality of symptom-based administration was 4.06 and for personality-based administration was 1.92 with a standard deviation of 3.91 and 3.29, respectively. The test result is statistically significant at 0.05 level (P < 0.05). Conclusion: Administration of individualised Homoeopathy medicine based on totality of symptoms is found to be more effective as compared to individualised Homoeopathy medicine based on personality amongst patients suffering from osteoarthritis knee.
背景:个体化是到达患者的形象,以选择补救措施的过程。病人个体化的习惯方法是通过构建症状的整体。顺势疗法中很少被探索的领域是完全基于人格特征的个体化。目的:本研究的目的是比较基于整体症状与-à-vis人格的个体化顺势疗法药物对膝骨关节炎患者的疗效。方法:对60例临床诊断为膝骨性关节炎的患者进行观察性研究,其中30例根据症状总体选择顺势疗法药物,30例根据患者个性选择顺势疗法药物。随机化使用计算机生成的数字。通过44项大五人格量表对患者进行人格评估。自制工具,将特质项目转录到顺势疗法资料库的标题中。比较治疗前后膝关节骨性关节炎患者生理功能评分、疼痛评分和患者总体评分(RAPID3)。结果:RAPID3在以症状为基础给药总体上的配对差异均值为4.06,在以人格为基础给药总体上的配对差异均值为1.92,标准差分别为3.91和3.29。检验结果在0.05水平上有统计学意义(P < 0.05)。结论:与基于个性的个体化顺势疗法药物相比,基于整体症状的个体化顺势疗法药物治疗对膝骨关节炎患者更有效。
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引用次数: 2
In vivo study of homoeopathic preparation of Gymnema sylvestre mother tincture, 30C and 200C on streptozotocin-induced diabetic rats 顺势制剂藤母酊剂30C和200C对链脲佐菌素诱导的糖尿病大鼠的体内研究
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_72_20
Avanish Shukla, I. Mhaisker, K. Rampal, R. Sheshala
Introduction: Gymnema sylvestre (GS) is a medicinal plant commonly used in complementary medicine to treat diabetes mellitus. This plant is proven scientifically to reduce blood glucose levels in the diabetic condition. However, till date, only little literature is published about the efficacy of GS prepared homoeopathically. Objective: In this study, we assessed the efficacy of homoeopathic preparation of GS (HPGS) in Q, 30C and 200C potencies in streptozotocin-induced diabetic rats. Materials and Methods: Diabetic rats were administered with 4.7 mL/kg of HPGS mother tincture (Q) for anti-hyperglycaemic efficacy on daily bases over a period of 14 days and HPGS Q, HPGS 30C and HPGS 200C potencies for dose-dependent testing on daily basis for 90 days. Results: On completion of treatment period, HPGS Q and HPGS 200C significantly reduced the blood glucose levels in diabetic rats (P < 0.05). Conclusion: Current research findings showed that HPGS mother tincture and HPGS 200C have the ability to lower blood glucose levels in diabetic rats, suggesting its efficacy in vivo.
简介:匙羹藤(Gymnema sylvestre, GS)是一种常用的辅助治疗糖尿病的药用植物。科学证明,这种植物可以降低糖尿病患者的血糖水平。然而,迄今为止,关于顺势疗法制备GS的疗效的文献很少。目的:观察顺势疗法制剂GS (HPGS)在Q、30C、200C三效期对链脲佐菌素诱导的糖尿病大鼠的作用。材料与方法:糖尿病大鼠每日给予4.7 mL/kg的HPGS母酊剂(Q)抗高血糖作用,连续14 d;每日给予HPGS Q、HPGS 30C、HPGS 200C三种药效,连续90 d进行剂量依赖性试验。结果:治疗结束时,HPGS Q、HPGS 200C均能显著降低糖尿病大鼠血糖水平(P < 0.05)。结论:目前的研究结果表明,HPGS母酊剂和HPGS 200C具有降低糖尿病大鼠血糖水平的作用,提示其体内有效。
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引用次数: 1
A group of homoeopathic medicines for COVID-19: A systematic review of clinical features 一组治疗COVID-19的顺势疗法药物:临床特征的系统综述
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_106_20
Horacio Escalante, N. Hasan, Adriana Delgado, S. Soto, Jessica Vivas
Background: Historically, several homoeopathic medicines are known to have attributed a significant role in the control and management of infectious epidemic diseases. Objectives: This study aimed to compile a list of prospective homoeopathic medicines for the treatment and prophylaxis of the COVID-19 epidemic by conducting a systematic review and statistical analysis of clinical characteristics of this emerging coronavirus disease. Materials and Methods: A> systematic review protocol was developed according to the reporting items of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Articles for review were selected from PubMed, World Health Organization database, MedRxiV, and BioRxiv. Studies in English and simplified Chinese from December 2019 to March 26 2020 were included. Data on clinical characteristics, laboratory and CT chest results of COVID-19 were extracted and analysed. Several symptoms and their intensity were statistically analysed. Results: Seventy-three studies were included. Amongst COVID-19 patients, fever (119.869 ± 24.425 [95% confidence intervals: 71.149–168.589]), dry cough (91.028 ± 19.555 [52.007–130.050]) and dyspnoea (24.594 ± 5.949 [12.722–36.465]) were the most common symptoms. Leucopenia (16.06 ± 5.07 [5.95–26.18]) in blood, ground-glass opacity (62.23 ± 18.82 [24.74–99.72]), patchy (21.48 ± 12.36 [3.13–46.11]) and consolidation (18.67 ± 9.18 [0.373–36.968]) in the lungs were observed. The selected sign and symptoms were repertorised, which resulted in a list of multiple homoeopathic medicines as potential medicines for COVID-19, led by Arsenic Album (94.59%) and Bryonia alba (91.89%). Conclusion: Considering the current clinical manifestations, this is a pioneer study related to finding a plausible list of homoeopathic medicines that might help the profession in the treatment as well as to select a prophylactic of COVID-19 disease.
背景:从历史上看,已知几种顺势疗法药物在传染病的控制和管理中发挥了重要作用。目的:本研究旨在通过对这种新出现的冠状病毒疾病的临床特征进行系统回顾和统计分析,编制一份用于治疗和预防新冠肺炎流行病的前瞻性顺势疗法药物清单。材料和方法:根据系统评价首选报告项目和荟萃分析报表的报告项目,制定系统评价方案。供审查的文章选自PubMed、世界卫生组织数据库、MedRxiV和BioRxiv。包括2019年12月至2020年3月26日期间的英语和简体中文学习。提取并分析了新冠肺炎的临床特征、实验室和CT胸部结果数据。对几种症状及其强度进行了统计分析。结果:纳入73项研究。在新冠肺炎患者中,发烧(119.869±24.425[95%置信区间:71.149–168.589])、干咳(91.028±19.555[52.007–130.050])和呼吸困难(24.594±5.949[12.722–36.465])是最常见的症状。观察到血液中的白细胞减少(16.06±5.07[5.95–26.18])、磨玻璃样混浊(62.23±18.82[24.74–99.72])、斑片状(21.48±12.36[3.13–46.11])和肺实变(18.67±9.18[0.373–36.968])。对所选体征和症状进行了再治疗,形成了多种同病药物作为新冠肺炎的潜在药物清单,以砷相册(94.59%)和白叶藻(91.89%)为首。结论:考虑到目前的临床表现,这是一项开拓性的研究,旨在寻找一份合理的顺势疗法药物清单,这可能有助于该行业的治疗以及选择新冠肺炎疾病的预防药物。
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引用次数: 3
A case report of hyperuricaemia with nephrolithiasis treated with homoeopathy 顺势疗法治疗高尿酸血症伴肾结石1例
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_6_20
Pooja Gautam
Introduction: Hyperuricaemia is serum urate concentration exceeding the limit of solubility, leading to its precipitation and predisposing the affected persons to gout. The increased level of uric acid in urinary excretion can also lead to nephrolithiasis. It has also been implicated as an indicator for diseases such as metabolic syndrome, diabetes mellitus, cardiovascular disease and chronic renal disease. Whereas homoeopathic literature enlists many medicines for this condition, there is a paucity of evidence-based published studies. Case Summary: The case presented here reported with the complaint of renal stone secondary to high serum uric acid levels. A single homoeopathic medicine Lycopodium was prescribed after thorough case taking which led to improvement in subjective symptoms and objectively reflecting in gradually decreasing levels of serum uric acid after elimination of stone. During the course of treatment, old symptoms also re-appeared depicting improvement in accordance with Hering's law of cure. The Modified Naranjo Criteria score after treatment was 8, which explicitly shows the positive causal attribution of the individualised homoeopathic medicine Lycopodium in this case. Homoeopathic treatment has shown favourable results in this case and demonstrates the scope of Homoeopathy in such cases.
简介:高尿酸血症是指血清尿酸盐浓度超过溶解度极限,导致其沉淀,使患者易患痛风。尿液排泄物中尿酸水平升高也会导致肾结石。它也被认为是代谢综合征、糖尿病、心血管疾病和慢性肾脏疾病等疾病的指标。尽管顺势疗法文献中有许多治疗这种疾病的药物,但很少有基于证据的已发表研究。病例总结:本文报告的病例为高血清尿酸水平继发肾结石。在彻底服药后,开了一种单一的顺势疗法药物Lycopodium,这导致主观症状的改善,并客观地反映为消除结石后血清尿酸水平的逐渐降低。在治疗过程中,旧的症状也再次出现,根据赫林治疗定律,症状有所改善。治疗后的改良Naranjo标准评分为8分,这明确显示了该病例中个体化顺势疗法药物Lycopodium的积极因果归因。顺势疗法在这种情况下显示出良好的结果,并证明了这种情况下顺势疗法的范围。
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引用次数: 4
Second wave of COVID-19: Steps and future vision 第二波新冠肺炎:步骤和未来愿景
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_52_21
A. Khurana
India has recently seen a devastating second wave of the COVID-19 pandemic, with a record high of over 414,000[1] new cases on 6th May 2021. The unprecedented wave hit the country in several ways, with many states imposing complete or partial lockdowns to check further spread, their people struggling to come to terms with magnitude of the wave, and most unfortunately, many families losing their dear ones to COVID-19. The entire world was hoping and praying for India’s recovery from this biggest jolt ever of severe acute respiratory syndrome coronavirus-2 virus epidemic.
印度最近经历了毁灭性的第二波COVID-19大流行,2021年5月6日新增病例超过41.4万例,创历史新高。这一前所未有的浪潮以多种方式袭击了美国,许多州实施了完全或部分封锁,以防止进一步传播,他们的人民难以接受这一浪潮的严重性,最不幸的是,许多家庭因COVID-19失去了亲人。整个世界都希望并祈祷印度从这场有史以来最严重的严重急性呼吸系统综合征冠状病毒-2疫情中恢复过来。
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引用次数: 1
Homoeopathic pathogenetic trial of Cuprum aceticum: A multicentric, double-blind, randomized, placebo controlled trial aceticum的同源致病性试验:一项多中心、双盲、随机、安慰剂对照试验
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_54_20
P. Mehra, A. Mahajan, A. Vichitra, B. Rajakumar, J. Singh, K. Banoth, B. Arya, A. Khurana, R. Manchanda, M. Padmanabhan
Background: Although the symptomatology of Cuprum metallicum is quite vast, its other salts have fragmentary proving. Thus, homoeopathic pathogenetic trial for Cuprum aceticum (Cu acet.) was taken up. Objective: To elicit the pathogenetic response to Cu acet. in homoeopathic potencies on healthy human provers. Materials and Methods: A multi-center, double-blind randomized, placebo controlled, trial was conducted at three centers of Central Council for Research in Homoeopathy. Proving was conducted on 50 relatively healthy provers selected after conducting the Pretrial Medical Examination. All the provers were given placebo during the first phase of the trial. In the next two phases, Cu acet. was administered in 6 C and 30 C potencies, in the intervention group (n = 34); and placebo in the placebo group (n = 16), after randomization. The proving data so generated on Cu acet. were compiled and analyzed at the proving-cum-data processing cell. Results: Out of 34 provers who were on actual drug trial, only 12 provers manifested symptoms. Twenty-six and 20 symptoms were manifested in 6C and 30C potency, respectively. Conclusion: The pathogenetic response elicited during the proving trial expands the scope of use of the homoeopathic medicine C. aceticum. The symptoms generated in this trial will carry more value when verified clinically.
背景:虽然金属铜的症状非常广泛,但其其他盐的证据并不完整。因此,对铜的顺势致病机理进行了研究。目的:探讨铜酸钠的发病机制。顺势疗法在健康人身上的有效性证明。材料与方法:在顺势疗法研究中央委员会的三个中心进行了一项多中心、双盲、随机、安慰剂对照的试验。对经过审前体检后选出的50名相对健康的证人进行了证明。在试验的第一阶段,所有的证明者都服用了安慰剂。在接下来的两个阶段中,Cu将继续。干预组分别给予6c和30c剂量(n = 34);随机化后,安慰剂组的安慰剂组(n = 16)。在cuacet上生成的证明数据。在验证和数据处理单元中进行编译和分析。结果:34例实际用药患者中,仅有12例出现症状。6C期和30C期分别出现症状26例和20例。结论:在验证试验中引起的发病反应扩大了顺势疗法药物黄芩的使用范围。本试验中产生的症状在临床验证后将具有更大的价值。
{"title":"Homoeopathic pathogenetic trial of Cuprum aceticum: A multicentric, double-blind, randomized, placebo controlled trial","authors":"P. Mehra, A. Mahajan, A. Vichitra, B. Rajakumar, J. Singh, K. Banoth, B. Arya, A. Khurana, R. Manchanda, M. Padmanabhan","doi":"10.4103/ijrh.ijrh_54_20","DOIUrl":"https://doi.org/10.4103/ijrh.ijrh_54_20","url":null,"abstract":"Background: Although the symptomatology of Cuprum metallicum is quite vast, its other salts have fragmentary proving. Thus, homoeopathic pathogenetic trial for Cuprum aceticum (Cu acet.) was taken up. Objective: To elicit the pathogenetic response to Cu acet. in homoeopathic potencies on healthy human provers. Materials and Methods: A multi-center, double-blind randomized, placebo controlled, trial was conducted at three centers of Central Council for Research in Homoeopathy. Proving was conducted on 50 relatively healthy provers selected after conducting the Pretrial Medical Examination. All the provers were given placebo during the first phase of the trial. In the next two phases, Cu acet. was administered in 6 C and 30 C potencies, in the intervention group (n = 34); and placebo in the placebo group (n = 16), after randomization. The proving data so generated on Cu acet. were compiled and analyzed at the proving-cum-data processing cell. Results: Out of 34 provers who were on actual drug trial, only 12 provers manifested symptoms. Twenty-six and 20 symptoms were manifested in 6C and 30C potency, respectively. Conclusion: The pathogenetic response elicited during the proving trial expands the scope of use of the homoeopathic medicine C. aceticum. The symptoms generated in this trial will carry more value when verified clinically.","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":"15 1","pages":"77 - 94"},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46509805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Homoeopathic management of wrist ganglion: Case series 顺势疗法治疗腕神经节:病例系列
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_29_20
Arunava Nath, D. Palit
Introduction: Ganglion cysts are soft tissue swellings occurring most commonly in the hand or wrist. Studies have reported 8%–50% of them resolve spontaneously in adults within 2 years approximately. Cases Summary: We present three cases of wrist ganglion treated successfully with individualized homoeopathic medicines; the results were evident within few weeks. Individual curative response of a homoeopathic medicine in each case was assessed through Modified Naranjo Criteria for Homoeopathy-Causal Attribution Inventory, which further elucidated role of constitutional treatment in homoeopathy.
简介:神经节囊肿是一种软组织肿胀,最常见于手或手腕。研究报告称,其中8%-50%在成年人中约2年内自发消退。病例总结:我们报告了三例腕神经节成功地用个体化的顺势疗法药物治疗;结果在几周内就显现出来了。通过改良Naranjo顺势疗法因果归因量表评估每个病例中顺势疗法药物的个体疗效,该量表进一步阐明了宪法治疗在顺势疗法中的作用。
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引用次数: 3
A 15-mm urinary calculus expelled with homoeopathic medicine - A case report 顺势疗法药物排出15mm尿路结石一例报告
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_19_20
S. Rai, K. Vineetha
Introduction: Renal or ureteric colic is an acute and severe pain caused by obstruction in the ureter. It usually occurs in the narrower areas of the ureter. It can be associated with severe pain, nausea, vomiting, urinary infections, haematuria, hydronephrosis, etc. Case Summary: A case of 15-mm calculus, lodged at the right ureterovesicular junction, presented with severe cutting pain extending downwards from the right lumbar region to the right groin area. The patient had severe pain at the conclusion of urination. Another calculus of size 10 mm in the lower calyx of the left kidney and 3.4-mm concretion in the right kidney was also detected. The homoeopathic medicine Sarsaparilla was given on the basis of totality of symptoms for 3 days. The pain reduced in 3 days and subsequent to an acute colicky pain and some bleeding, on the 11th day, the stone was expelled. This case report shows the potential of Homoeopathy in cases of large urinary calculi.
引言:肾或输尿管绞痛是由输尿管梗阻引起的急性和严重疼痛。它通常发生在输尿管狭窄的区域。它可能伴有剧烈疼痛、恶心、呕吐、泌尿系统感染、血尿、肾积水等。病例摘要:一例15毫米结石,位于右输尿管膀胱交界处,表现为从右腰部向下延伸至右腹股沟的严重切割疼痛。病人在排尿结束时感到剧烈疼痛。在左肾下肾盏中还检测到另一个大小为10mm的结石,在右肾中也检测到3.4mm的结石。根据症状的总体情况给予顺势疗法药物Sarsaparilla治疗3天。疼痛在3天内减轻,随后出现急性绞痛和一些出血,在第11天,结石被排出。本病例报告显示了在大的尿路结石病例中顺势疗法的潜力。
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引用次数: 2
Physicochemical standardisation of the homoeopathic drug Rumex acetosella and its comparison with another homoeopathic drug, Rumex crispus 顺势药物牛蒡的理化标准及其与另一顺势药物牛蒡的比较
Q3 Medicine Pub Date : 2021-04-01 DOI: 10.4103/ijrh.ijrh_104_19
Dr. Bibaswan Biswas, Dr. Anjali Chatterjee, Nilakshi Dey, G. Kumar, R. Arya, A. Khurana
Background: Rumex acetosella, a relatively new drug in the homoeopathic system, is traditionally used for treating inflammation, diabetes and gastrointestinal problems, especially diarrhoea. Objective: The aim of this work is to report physicochemical standardisation of the homoeopathic drug, Rumex acetosella. Further, we propose our simple and economical method to differentiate it with a closely related species, Rumex crispus. Materials and Methods: The physicochemical study measuring several parameters was done. The pH of the mother tincture (MT) and the water extract was measured and compared. Furthermore, the chemical composition of the Rumex acetosella MT were compared with taxonomically closely related Rumex crispus MT by thin layer chromatography (TLC). Results: The results show a strong relationship between the extracting solvent's polarity and its extracting power. A simple TLC study shows a strong correlation between two drugs of the same genus, Rumex, but they can be differentiated by their unique spots. Conclusion: Our study not only provides the physicochemical standards for the drug Rumex acetosella but also shows that a simple analytical technique, a manual TLC can easily be used to distinguish two taxonomically close homoeopathic drugs.
背景:牛蒡是一种在顺势疗法系统中相对较新的药物,传统上用于治疗炎症、糖尿病和胃肠道疾病,特别是腹泻。目的:报道顺势疗法药物牛蹄草的理化标准。此外,我们还提出了一种简单而经济的方法来区分它与一个近缘种——crispus。材料与方法:进行了理化研究,测定了几个参数。测定了母酊剂(MT)和水提物的pH值,并进行了比较。采用薄层色谱法对其化学成分进行了比较。结果:萃取溶剂极性与萃取力有密切关系。一项简单的薄层色谱研究表明,同一属的两种药物之间具有很强的相关性,但它们可以通过其独特的斑点来区分。结论:本研究不仅为该药物的理化标准提供了依据,而且表明手工薄层色谱法这一简单的分析技术可以很容易地区分两种相近的顺势疗法药物。
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引用次数: 2
Usefulness of individualised homoeopathic medicine in Manic episode - A case report 个体化顺势疗法药物在躁狂发作中的应用- 1例报告
Q3 Medicine Pub Date : 2021-01-01 DOI: 10.4103/ijrh.ijrh_25_20
SKarunakara Moorthi, P. Radhika, K. Muraleedharan
Introduction: Mania is a form of mood disorder initially, characterised by elevated mood, insomnia, increased libido and grandiosity. More severe forms develop elation and grandiose delusions. Case Summary: A patient reported in the Out Patient Department with symptoms of increased delusions for 3 weeks. The consultant psychiatrist diagnosed it as a case of bipolar affective disorder, current episode manic with psychotic features. Young mania rating scale (YMRS) scored 38 at the time of admission. Lachesis mutus 200 was prescribed initially and later Lycopodium clavatum 200 was prescribed, as the symptom picture changed. Overall improvement was noticed clinically and in YMRS after treatment. In this case, individualised homoeopathic treatment has shown a positive role for the remission of manic episode with psychotic features without the support adjunctive therapy or conventional medication in the current episode.
简介:躁狂最初是一种情绪障碍,其特征是情绪升高、失眠、性欲增强和浮夸。更严重的形式发展为兴高采烈和浮夸的妄想。病例总结:一位在门诊部报告的患者妄想症状加重3周。精神科顾问诊断为双相情感障碍,现躁狂发作伴精神病性特征。青少年躁狂症量表(YMRS)在入院时得分为38分。随着症状的改变,最初开的处方是麝香草200,后来开的处方是棒状石蒜200。治疗后临床及YMRS均有整体改善。在本例中,个体化的顺势疗法治疗在没有辅助治疗或传统药物支持的情况下,对具有精神病性特征的躁狂发作的缓解有积极作用。
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引用次数: 3
期刊
Indian Journal of Research in Homoeopathy
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