Introduction: Post-herpetic neuralgia (PHN) is the most troublesome complication of herpes zoster (HZ). It often occurs in elderly and immunocompromised persons. PHN is a chronic neuropathic pain that can persist months to years after HZ rashes have healed. The persisting pain causes physical and psychological distress and negatively impacts the quality of life. The conventional method of treatment (CMT) is often only partially effective. In patients with inadequate response, or intolerance to current conventional treatments for pain relief, homoeopathy may be considered. Case Summary: A 64-year-old woman presented with severe neuralgic pain on the right upper chest wall and upper arm with a recent history of HZ. The acute neuralgic pain was accompanied with HZ rashes. Within 1 month of CMT, HZ healed, but neuralgic pain persisted. Homoeopathic medicines Hypericum perforatum and Sulphur were prescribed as per the totality of symptoms and individualisation, which relieved PHN (assessed by ‘Visual Analogue Scale’ [VAS]). It was accompanied with relief in associated symptoms and improvement in functional daily activities. The causal attribution of the improvement was assessed using the Modified Naranjo Criteria. This case report suggests that homoeopathic intervention may be the choice of treatment for relief of pain of PHN along with improvement in the psychological distress and quality of life.
{"title":"Elderly patient with post-herpetic neuralgia treated with homoeopathic medicine: A case report","authors":"Suraia Parveen, Subhra Das","doi":"10.53945/2320-7094.1034","DOIUrl":"https://doi.org/10.53945/2320-7094.1034","url":null,"abstract":"Introduction: Post-herpetic neuralgia (PHN) is the most troublesome complication of herpes zoster (HZ). It often occurs in elderly and immunocompromised persons. PHN is a chronic neuropathic pain that can persist months to years after HZ rashes have healed. The persisting pain causes physical and psychological distress and negatively impacts the quality of life. The conventional method of treatment (CMT) is often only partially effective. In patients with inadequate response, or intolerance to current conventional treatments for pain relief, homoeopathy may be considered. Case Summary: A 64-year-old woman presented with severe neuralgic pain on the right upper chest wall and upper arm with a recent history of HZ. The acute neuralgic pain was accompanied with HZ rashes. Within 1 month of CMT, HZ healed, but neuralgic pain persisted. Homoeopathic medicines Hypericum perforatum and Sulphur were prescribed as per the totality of symptoms and individualisation, which relieved PHN (assessed by ‘Visual Analogue Scale’ [VAS]). It was accompanied with relief in associated symptoms and improvement in functional daily activities. The causal attribution of the improvement was assessed using the Modified Naranjo Criteria. This case report suggests that homoeopathic intervention may be the choice of treatment for relief of pain of PHN along with improvement in the psychological distress and quality of life.","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47866903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Another pandemic year: What it means for homoeopathy","authors":"Anil Khurana","doi":"10.53945/2320-7094.1120","DOIUrl":"https://doi.org/10.53945/2320-7094.1120","url":null,"abstract":"","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42557108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Intellectual disability (ID) is characterised by below-average intelligence and a lack of skills necessary for day-to-day living. A study was conducted by our institute at a school for students of special needs. Objectives: The objectives of the study were to demonstrate the role of homoeopathic management in ID. Methods: A purposive, non-randomised, self-controlled, preand post-intervention study of 25 participants was done. The initial 6 months were the control period, thereafter, the same participants were treated for 18 months, with homoeopathy. Treatment outcomes were assessed using domains of Diagnostic and Statistical Manual-V-V. Scores of each domain were observed at 6 months interval and analysed. Results: A statistically significant difference (P < 0.001) was observed in adaptive functioning treatment scores for conceptual domain, social domain and practical domain. It justifies the clinically significant improvement in the features of ID, reflected in all domains of adaptive functioning, cognition, hyperactivity, behavioural dysfunction and communication difficulty. Furthermore, it was seen that the dosage of pharmacological medicines was gradually tapered off in most cases. Conclusion: The study has demonstrated the utility of homoeopathic treatment as an adjuvant in the management of ID, which is reflected through significant improvement in psychosocial adaptation of the subjects and improved their quality of life. Acknowledgments and Source of Funding Nil This original article is available in Indian Journal of Research in Homoeopathy: https://ijrh.researchcommons.org/ journal/vol15/iss4/2
背景:智力残疾(ID)的特征是智力低于平均水平，缺乏日常生活所需的技能。我们研究所在一所有特殊需要的学生学校进行了一项研究。目的:本研究的目的是证明顺势疗法治疗在ID中的作用。方法:一项有目的、非随机、自我控制、干预前和干预后25名参与者的研究。最初的6个月为对照期，之后，同样的参与者用顺势疗法治疗18个月。使用诊断和统计手册- v - v的域评估治疗结果。每隔6个月观察各领域评分并进行分析。结果:适应功能治疗在概念领域、社会领域和实践领域得分差异有统计学意义(P < 0.001)。这证明了ID的临床显著改善，反映在适应功能、认知、多动、行为障碍和沟通困难的所有领域。此外，在大多数情况下，药理学药物的剂量逐渐减少。结论:本研究证明了顺势疗法作为辅助治疗ID的效用，这反映在受试者的社会心理适应和生活质量的显著改善上。本文原文发表于印度顺势疗法研究杂志:https://ijrh.researchcommons.org/ Journal /vol15/iss4/2
{"title":"Role of adjuvant homoeopathic medicines in the management of intellectual disability – A purposive, non-randomised, self-controlled, pre- and post-intervention pilot study","authors":"Dhara Arora","doi":"10.53945/2320-7094.1079","DOIUrl":"https://doi.org/10.53945/2320-7094.1079","url":null,"abstract":"Background: Intellectual disability (ID) is characterised by below-average intelligence and a lack of skills necessary for day-to-day living. A study was conducted by our institute at a school for students of special needs. Objectives: The objectives of the study were to demonstrate the role of homoeopathic management in ID. Methods: A purposive, non-randomised, self-controlled, preand post-intervention study of 25 participants was done. The initial 6 months were the control period, thereafter, the same participants were treated for 18 months, with homoeopathy. Treatment outcomes were assessed using domains of Diagnostic and Statistical Manual-V-V. Scores of each domain were observed at 6 months interval and analysed. Results: A statistically significant difference (P < 0.001) was observed in adaptive functioning treatment scores for conceptual domain, social domain and practical domain. It justifies the clinically significant improvement in the features of ID, reflected in all domains of adaptive functioning, cognition, hyperactivity, behavioural dysfunction and communication difficulty. Furthermore, it was seen that the dosage of pharmacological medicines was gradually tapered off in most cases. Conclusion: The study has demonstrated the utility of homoeopathic treatment as an adjuvant in the management of ID, which is reflected through significant improvement in psychosocial adaptation of the subjects and improved their quality of life. Acknowledgments and Source of Funding Nil This original article is available in Indian Journal of Research in Homoeopathy: https://ijrh.researchcommons.org/ journal/vol15/iss4/2","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43519123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: As much as the prevention and treatment of COVID 19 has posed challenge, its post infection sequelae have not been any less challenging. There has been an emerging menace and concern for post COVID 19 illnesses. Patients with microbiological recovery from COVID‐19 show most common symptoms like fatigue, dyspnoea, cough, headache, tightness of chest, arthralgia, muscle pain with drop in the quality of life. Limited treatment options are available in the conventional set up. Cases summary: We present nine cases that were treated for post COVID 19 symptoms at Regional Research Institute (H.), Mumbai, under Central Council for Research in Homoeopathy. Out of these, seven cases were of acute Post Covid condition and two presented with Chronic Covid sequelae. All these patients were under standard conventional care/treatment but had no resolution of Post Covid symptoms. The Post Covid symptoms reported in these cases were fatigue, dyspnoea on exertion, cough, profuse perspiration, chest tightness and profuse perspiration. Bryonia Alba was the most useful remedy apart from Sulphur, Arsenicum Album, Rhus Toxicodendron and Calcarea Carbonicum. The cases have demonstrated a positive role of homoeopathic treatment in relieving the Post COVID illnesses. Acknowledgments and Source of Funding
{"title":"Homoeopathy for Post COVID 19 illnesses: A Case Series","authors":"V. Shinde, Ramesh Bawaskar","doi":"10.53945/2320-7094.1029","DOIUrl":"https://doi.org/10.53945/2320-7094.1029","url":null,"abstract":"Introduction: As much as the prevention and treatment of COVID 19 has posed challenge, its post infection sequelae have not been any less challenging. There has been an emerging menace and concern for post COVID 19 illnesses. Patients with microbiological recovery from COVID‐19 show most common symptoms like fatigue, dyspnoea, cough, headache, tightness of chest, arthralgia, muscle pain with drop in the quality of life. Limited treatment options are available in the conventional set up. Cases summary: We present nine cases that were treated for post COVID 19 symptoms at Regional Research Institute (H.), Mumbai, under Central Council for Research in Homoeopathy. Out of these, seven cases were of acute Post Covid condition and two presented with Chronic Covid sequelae. All these patients were under standard conventional care/treatment but had no resolution of Post Covid symptoms. The Post Covid symptoms reported in these cases were fatigue, dyspnoea on exertion, cough, profuse perspiration, chest tightness and profuse perspiration. Bryonia Alba was the most useful remedy apart from Sulphur, Arsenicum Album, Rhus Toxicodendron and Calcarea Carbonicum. The cases have demonstrated a positive role of homoeopathic treatment in relieving the Post COVID illnesses. Acknowledgments and Source of Funding","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48659414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Treatment of infantile spasms (ISs) with allopathic medicines along with homeopathy is poorly understood in context with the seizure profile, psychomotor outcome, and electroencephalogram (EEG) changes. Objectives: The objective of the study was to evaluate the role of homeopathic treatment in seizure control, psychomotor development, and EEG changes in patients of IS. Materials and Methods: An open label, single-arm, clinical trial was conducted. Patients found eligible were enrolled (n = 30) and given individualized homeopathic intervention along with conventional medicine for 3 months. Follow-up assessment was done weekly based on 7 points: Sense of well-being, changes in cognitive behavior, changes in activity level, changes in seizure ictal period, changes in hypsarrhythmia, changes in speech, and gross and fine motor development. Results: About 76.66% (n = 23) of patients had improved clinically (sense of well-being, activity level, and seizure ictal period). Cognitive behavior improved in 50% (n = 9), while hypsarrhythmia improved in 16.66% (n = 5) of patients. Speech improved in 13.33% (n = 4), while gross and fine motor skills improved in 21% (n = 4) and 16% (n = 4), respectively. Calcarea carbonica (n = 4, 13.33%), Arsenic album (n = 4, 13.33%), Causticum (n = 4, 13.33%), Lycopodium (n = 3, 10%), and Nux vomica (n = 2, 6.66%) were frequently used medicines. Conclusion: Homeopathy plays a positive role in seizures in IS patients. More multicentric, randomized trials are required to make conclusions. Acknowledgments and Source of Funding N/A This original article is available in Indian Journal of Research in Homoeopathy: https://ijrh.researchcommons.org/ journal/vol15/iss3/3
{"title":"Homoeopathy for infantile spasms: An open label, single arm, clinical trial","authors":"Savita Kumari, N. Kalra","doi":"10.53945/2320-7094.1036","DOIUrl":"https://doi.org/10.53945/2320-7094.1036","url":null,"abstract":"Background: Treatment of infantile spasms (ISs) with allopathic medicines along with homeopathy is poorly understood in context with the seizure profile, psychomotor outcome, and electroencephalogram (EEG) changes. Objectives: The objective of the study was to evaluate the role of homeopathic treatment in seizure control, psychomotor development, and EEG changes in patients of IS. Materials and Methods: An open label, single-arm, clinical trial was conducted. Patients found eligible were enrolled (n = 30) and given individualized homeopathic intervention along with conventional medicine for 3 months. Follow-up assessment was done weekly based on 7 points: Sense of well-being, changes in cognitive behavior, changes in activity level, changes in seizure ictal period, changes in hypsarrhythmia, changes in speech, and gross and fine motor development. Results: About 76.66% (n = 23) of patients had improved clinically (sense of well-being, activity level, and seizure ictal period). Cognitive behavior improved in 50% (n = 9), while hypsarrhythmia improved in 16.66% (n = 5) of patients. Speech improved in 13.33% (n = 4), while gross and fine motor skills improved in 21% (n = 4) and 16% (n = 4), respectively. Calcarea carbonica (n = 4, 13.33%), Arsenic album (n = 4, 13.33%), Causticum (n = 4, 13.33%), Lycopodium (n = 3, 10%), and Nux vomica (n = 2, 6.66%) were frequently used medicines. Conclusion: Homeopathy plays a positive role in seizures in IS patients. More multicentric, randomized trials are required to make conclusions. Acknowledgments and Source of Funding N/A This original article is available in Indian Journal of Research in Homoeopathy: https://ijrh.researchcommons.org/ journal/vol15/iss3/3","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41960699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Central Council for Research in Homoeopathy organized a scientific convention on the World Homoeopathy Day on 10th and 11thApril, 2021 to commemorate the 266th birth anniversary of Dr Christian Fredrich Samuel Hahnemann at Vigyan Bhawan, New Delhi, India. The theme of the conference was ‘Homoeopathy – Roadmap for Integrative Medicine’. There were oral presentations and a panel discussion during the convention organized in the hybrid mode, with participants and presenters attending the convention either physically, or remotely through video link. Recommendations to develop a roadmap for Homoeopathy for integrative care were also proposed during the convention. Integration is not simply co-location of all systems but a wholesome clinical approach for the public health benefit where systems have known limitations. Specific strategic actions are needed at research, practice and education levels to promote integrative care with Homoeopathy as a key contributor. Acknowledgments and Source of Funding Financial support and sponsorship: Nil This conference report is available in Indian Journal of Research in Homoeopathy: https://ijrh.researchcommons.org/ journal/vol15/iss3/5
顺势疗法研究中央委员会于2021年4月10日和11日世界顺势疗法日在印度新德里的Vigyan Bhawan组织了一次科学大会，以纪念Christian Fredrich Samuel Hahnemann博士诞辰266周年。会议的主题是“顺势疗法——中西医结合的路线图”。大会期间以混合模式组织了口头报告和小组讨论，与会者和演讲人或亲自出席会议，或通过视频连接远程参加会议。会议期间还提出了制定顺势疗法综合护理路线图的建议。整合不是简单地将所有系统置于同一地点，而是在已知系统存在局限性的情况下，为公共卫生利益提供一种有益的临床方法。需要在研究、实践和教育层面采取具体的战略行动，以促进以顺势疗法为主要贡献者的综合护理。本次会议报告发表于印度顺势疗法研究杂志:https://ijrh.researchcommons.org/ Journal /vol15/iss3/5
{"title":"National Convention on World Homoeopathy Day – A conference report","authors":"Anupam Mukherjee, D. Taneja, A. Khurana","doi":"10.53945/2320-7094.1038","DOIUrl":"https://doi.org/10.53945/2320-7094.1038","url":null,"abstract":"Central Council for Research in Homoeopathy organized a scientific convention on the World Homoeopathy Day on 10th and 11thApril, 2021 to commemorate the 266th birth anniversary of Dr Christian Fredrich Samuel Hahnemann at Vigyan Bhawan, New Delhi, India. The theme of the conference was ‘Homoeopathy – Roadmap for Integrative Medicine’. There were oral presentations and a panel discussion during the convention organized in the hybrid mode, with participants and presenters attending the convention either physically, or remotely through video link. Recommendations to develop a roadmap for Homoeopathy for integrative care were also proposed during the convention. Integration is not simply co-location of all systems but a wholesome clinical approach for the public health benefit where systems have known limitations. Specific strategic actions are needed at research, practice and education levels to promote integrative care with Homoeopathy as a key contributor. Acknowledgments and Source of Funding Financial support and sponsorship: Nil This conference report is available in Indian Journal of Research in Homoeopathy: https://ijrh.researchcommons.org/ journal/vol15/iss3/5","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43213990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Homoeopathy in Covid19: Building Evidence","authors":"A. Khurana","doi":"10.53945/2320-7094.1085","DOIUrl":"https://doi.org/10.53945/2320-7094.1085","url":null,"abstract":"","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41951059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research Highlights (July-September 2021)","authors":"Navita Bagdi","doi":"10.53945/2320-7094.1011","DOIUrl":"https://doi.org/10.53945/2320-7094.1011","url":null,"abstract":"","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49230333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Homoeopathic medicine Arsenicum album (Ars. alb) has been advised by the Ministry of AYUSH, Government of India based on the recommendations of Central Council for Research in Homoeopathy (CCRH) as a prophylactic/ immune booster for prevention of COVID-19 disease. This paper narrates available evidence from laboratory studies, clinical studies, toxicological studies for Ars. alb. as a prophylactic/ immune booster. Methods: Published literature regarding immuno-modulatory, toxicological and therapeutic effects of the Homoeopathic Medicine Ars. alb. was reviewed. Results: Homoeopathic literature records the use of Ars.alb. for fever, cough, shortness of breath, loss of smell, coryza, fatigue, diarrhea, nausea, etc. Ars. alb. in its crude form is toxic, acting over numerous systems of the human body. It acts over the macrophages and lymphocytes hindering normal immune response. The toxic effects of crude arsenic are neutralized by ultra-high dilution of arsenic trioxide thus stimulating an immune response, the memory of which retained by the organism helps to prevent the infection. Highly diluted Ars.alb. modulates reactive oxygen species (ROS), and cytokine secretion, decrease in interleukin-6 production in macrophages, which are central mediators of the immune system, wound healing, and body homeostasis. The molecular effects and clinical presentation of the COVID-19 and Ars. alb. are similar over the response to the immune system and clinically is similar to a great extent. Conclusion: Primary evidence suggests possibility of homoeopathic medicine Ars. alb. as a prophylactic immune booster medicine, maintaining an optimal immune response in the human body. Further preclinical and clinical studies are warranted. Acknowledgments and Source of Funding
背景:顺势疗法药物Arsenicum album (Ars。印度政府AYUSH部根据顺势疗法研究中央委员会(CCRH)的建议，建议将alb作为预防COVID-19疾病的预防性/免疫增强剂。本文叙述了从实验室研究、临床研究和毒理学研究中获得的证据。铝青铜。作为预防/免疫增强剂。方法:查阅已发表的有关顺势疗法药物的免疫调节、毒理学和治疗作用的文献。铝青铜。综述了。结果:顺势疗法文献记录了白藜芦醇的使用。用于发热、咳嗽、气短、嗅觉丧失、鼻塞、疲劳、腹泻、恶心等。农业研究所。铝青铜。它的原始形态是有毒的，对人体的许多系统起作用。它作用于巨噬细胞和淋巴细胞，阻碍正常的免疫反应。粗砷的毒性作用可通过超高稀释的三氧化二砷来中和，从而刺激免疫反应，生物体对其保留的记忆有助于预防感染。高度稀释的砷。调节活性氧(ROS)和细胞因子分泌，减少巨噬细胞中白细胞介素-6的产生，巨噬细胞是免疫系统、伤口愈合和身体稳态的中心介质。COVID-19和Ars的分子效应和临床表现。铝青铜。在免疫系统的反应上是相似的，在临床上也是很大程度上相似的。结论:初步证据提示顺势疗法药物的可能性。铝青铜。作为一种预防性免疫增强药物，维持人体内最佳的免疫反应。进一步的临床前和临床研究是必要的。致谢和资金来源
{"title":"Homoeopathic Medicine Arsenicum album, the prophylactic/immune booster in COVID-19 pandemic","authors":"Baidurjya Bhattacharjee, V. Roja, A. Khurana","doi":"10.53945/2320-7094.1028","DOIUrl":"https://doi.org/10.53945/2320-7094.1028","url":null,"abstract":"Background: Homoeopathic medicine Arsenicum album (Ars. alb) has been advised by the Ministry of AYUSH, Government of India based on the recommendations of Central Council for Research in Homoeopathy (CCRH) as a prophylactic/ immune booster for prevention of COVID-19 disease. This paper narrates available evidence from laboratory studies, clinical studies, toxicological studies for Ars. alb. as a prophylactic/ immune booster. Methods: Published literature regarding immuno-modulatory, toxicological and therapeutic effects of the Homoeopathic Medicine Ars. alb. was reviewed. Results: Homoeopathic literature records the use of Ars.alb. for fever, cough, shortness of breath, loss of smell, coryza, fatigue, diarrhea, nausea, etc. Ars. alb. in its crude form is toxic, acting over numerous systems of the human body. It acts over the macrophages and lymphocytes hindering normal immune response. The toxic effects of crude arsenic are neutralized by ultra-high dilution of arsenic trioxide thus stimulating an immune response, the memory of which retained by the organism helps to prevent the infection. Highly diluted Ars.alb. modulates reactive oxygen species (ROS), and cytokine secretion, decrease in interleukin-6 production in macrophages, which are central mediators of the immune system, wound healing, and body homeostasis. The molecular effects and clinical presentation of the COVID-19 and Ars. alb. are similar over the response to the immune system and clinically is similar to a great extent. Conclusion: Primary evidence suggests possibility of homoeopathic medicine Ars. alb. as a prophylactic immune booster medicine, maintaining an optimal immune response in the human body. Further preclinical and clinical studies are warranted. Acknowledgments and Source of Funding","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46524575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background Mangifera indica is widely used in the Homoeopathy systems of medicine. In Homoeopathy, Mang. ind. is one of the indicated medicines for passive haemorrhages, uterine, renal and gastric problems. Mangiferin is a xanthanoid present in leaves, stalks barks, peel and kernel of the mango plant. Mangiferin has antioxidant, antiviral, anticancer, antidiabetic, antiaging, immunomodulatory, hepatoprotective and analgesic properties. Therefore in the current study, we have tried to identify mangiferin and its antioxidant properties in Mang. ind. homoeopathic mother tincture. Objective The aim of the present study wais to identify Mangiferin, Total Phenol Content (TPC) and Total Flavonoid Content (TFC) in Mang. ind. homoeopathic mother tincture. Materials and Methods Mangiferin (A) was used as a primary reference standard and in sample In-house prepared mother tincture (B) and two different market samples (C and D) were used. An authentic sample of Mang. ind. bark was received from the Centre of Medicinal Plants Research in Homoeopathy, Emerald, Tamil Nadu, India for preparation of in house mother tincture. Results We have successfully identified Mangiferin in Mang. ind. in-house prepared mother tincture (B) and two market samples (C and D) by HPTLC. Total Phenolic Content (TPC) and Total Flavonoid Content (TFC) was determined by Ultraviolet–visible spectroscopy. Conclusion High Performance Thin Layer Chromatography study confirms the presence of Mangiferin whereas U. V spectroscopy proves to be a useful tool for in-vitro antioxidant assay study. Acknowledgments and Source of Funding
{"title":"High-performance thin-layer chromatography fingerprinting and antioxidant study of Mangifera indica mother tincture","authors":"B. Dwivedi, Manoj Kumar, Rakhi Mishra","doi":"10.53945/2320-7094.1033","DOIUrl":"https://doi.org/10.53945/2320-7094.1033","url":null,"abstract":"Background Mangifera indica is widely used in the Homoeopathy systems of medicine. In Homoeopathy, Mang. ind. is one of the indicated medicines for passive haemorrhages, uterine, renal and gastric problems. Mangiferin is a xanthanoid present in leaves, stalks barks, peel and kernel of the mango plant. Mangiferin has antioxidant, antiviral, anticancer, antidiabetic, antiaging, immunomodulatory, hepatoprotective and analgesic properties. Therefore in the current study, we have tried to identify mangiferin and its antioxidant properties in Mang. ind. homoeopathic mother tincture. Objective The aim of the present study wais to identify Mangiferin, Total Phenol Content (TPC) and Total Flavonoid Content (TFC) in Mang. ind. homoeopathic mother tincture. Materials and Methods Mangiferin (A) was used as a primary reference standard and in sample In-house prepared mother tincture (B) and two different market samples (C and D) were used. An authentic sample of Mang. ind. bark was received from the Centre of Medicinal Plants Research in Homoeopathy, Emerald, Tamil Nadu, India for preparation of in house mother tincture. Results We have successfully identified Mangiferin in Mang. ind. in-house prepared mother tincture (B) and two market samples (C and D) by HPTLC. Total Phenolic Content (TPC) and Total Flavonoid Content (TFC) was determined by Ultraviolet–visible spectroscopy. Conclusion High Performance Thin Layer Chromatography study confirms the presence of Mangiferin whereas U. V spectroscopy proves to be a useful tool for in-vitro antioxidant assay study. Acknowledgments and Source of Funding","PeriodicalId":13469,"journal":{"name":"Indian Journal of Research in Homoeopathy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43949183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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