Integrative medicine最新文献

Background: Rheumatoid arthritis (RA) is an autoimmune disease with prolonged dysregulation of pro- and anti-inflammatory immune pathways resulting in chronic inflammation, which alters the functional status and quality of life. The present study aimed to assess the short-term effect of yoga therapy on systemic inflammatory markers and quality of life among RA patients.

Methods: The study included one hundred RA patients aged 18-60 years and randomized into yoga (n = 50) and control (n = 50) groups. A structured yoga therapy was given for 12 weeks along with their regular disease-modifying antirheumatic medications (DMARDs). During the study period, all the participants were allowed to continue their daily lifestyle and diet.

Results: After 12 weeks of intervention, the yoga group reported a significant decrease in interleukin-6 (IL 6) (P < .001), C-reactive protein (CRP) (P < .01), rheumatoid factor (RA factor) (P = .02), and erythrocyte sedimentation rate (ESR) (P = .05), compared to the control group. Furthermore, compared to the control group, yoga participants showed significant improvement in functional status and disease activity, which included the assessment of DAS-28 (to assess the disease activity) (P < .001), patient global assessment (P < .001), and reduced Visual Analogue Scale (VAS) score (pain intensity assessment) (P < .01). The secondary outcome was the quality of life (SF-36 questionnaire), which showed significant improvement post-intervention (P = .05).

Conclusion: The present study has demonstrated that short-term yoga therapy could lower systemic inflammatory markers by maintaining immune homeostasis to improve the functional status and quality of life in RA patients.

Introduction: GLP-1 medications are widely used for weight loss in patients with and without type 2 diabetes. However, limited research exists on their effects in non-diabetic patients, particularly concerning mitochondrial function. This case report investigates the potential of altered mitochondrial dysfunction as a cause of side effects of GLP-1 medications in patients without type 2 diabetes.

Case presentation: The patient, a 43-year-old female with a BMI of 32, presented with hypoglycemia and persistent migraines with auras after Ozempic and Mounjaro injections.

Outcomes: The patient changed her diet to include 90 grams of protein and frequent small meals throughout the day. She took CoQ10, D-ribose, vitamin B complex, and acetyl-l-carnitine, to address the migraines, and this also improved the mitochondrial function. The patient reported balanced blood sugar after changing her diet; her migraines improved and did not return after taking supplementation.

Conclusion: This case report emphasizes the need for awareness and monitoring of potential mitochondrial side effects from GLP-1 injections in patients without type 2 diabetes. Nutritional and supplemental interventions effectively managed the patient's symptoms and emphasized the need for tailored interventions in patients using GLP-1 medications. Further research is needed to understand how GLP-1 injections impact mitochondrial function.

Environmental radiation is one of the key causes of the increased prevalence of infertility among couples. This type of radiation can be ionizing or non-ionizing. While ionizing radiation is known to cause sterility in both males and females, the role of low-energy non-ionizing radiation is still debated. This article will discuss the various types of environmental radiation and its consequences on male and female fertility. Recent studies suggest that continuous exposure to low-energy, non-ionizing radiation might also result in infertility. The sources of this type of radiation are generally man-made, including mobile phones, television broadcasts, radio, radars, etc. The ever-increasing use of these devices in our daily lives has introduced a new type of pollution called electropollution. The mechanisms of action by which electropollution causes infertility are still being investigated. In males, prolonged exposure to this type of radiation might negatively impact sperm parameters, such as count, motility, morphology, and viability. The evidence for female infertility caused by non-ionizing radiation is still evolving.

Clearly the current way we address health and disease in the United States is not working. We now suffer the highest burden of chronic disease in every age group ever in human history. And, at the same time, we have the most expensive health care system ever. Why? Because the actual causes of disease are not being addressed. Eight years ago, when you were first elected president, I gathered together the leadership of natural, integrative, functional, and environmental medicine to provide guidance on what needed to change. Unfortunately, none of our recommendations were addressed, every measure of health and disease burden has worsened, and health care costs continue to increase far beyond the rate of inflation. President Trump, please take a look and consider these recommendations.