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Empty pelvis syndrome as a cause of major morbidity after pelvic exenteration: validation of a core data set. 骨盆空综合征是骨盆切除后主要发病的原因:对核心数据集的验证。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf070
Charles T West,Abhinav Tiwari,Julian Smith,Hideaki Yano,Malcolm A West,Alex H Mirnezami,
BACKGROUNDPelvic exenteration (PE) is a potentially curative treatment for advanced pelvic cancers. However, PE procedures are associated with empty pelvis syndrome (EPS), a spectrum of complications including pelvic sepsis, sinus formation, fistulae, and bowel obstruction. Inconsistent reporting has impeded progress in understanding EPS. The PelvEx Collaborative introduced a core data set of descriptors and outcomes to address these issues and the aim of this study was to validate this data set.METHODSAn observational cohort study applied the EPS core data set to a prospectively maintained PE database. Patterns of major and minor manifestations were evaluated; logistic regression was used to explore relationships between descriptors and outcomes, and inter-descriptor correlation was assessed using Cramer's V.RESULTSEPS occurred in 32.1% of patients (105 of 327) and was the leading cause of major morbidity. Infected pelvic collections (occurring in 23.5%) were associated with subsequent chronic sinus formation (OR 3.08, P = 0.01) and fistulae (P = 0.05). The risk of EPS increased with external beam radiotherapy (OR 1.01 per 1 Gy, P = 0.01), sacrectomy (OR 3.78, P < 0.001), total cystectomy (OR 2.46, P = 0.001), internal iliac vessel ligation (unilateral OR 1.94, P = 0.045; bilateral OR 3.65, P < 0.001), and infralevator exenteration (OR 3.69, P < 0.001). Omentoplasty reduced pelvic bowel obstruction (OR 0.27, P = 0.004) and perineal flaps were linked to a higher rate of reconstruction-related major morbidity compared with biological mesh alone (20.8% versus 1.2% respectively, P = 0.002).CONCLUSIONThe PelvEx Collaborative core data set standardizes reporting of EPS, with this study detailing the acute and chronic complications arising as a consequence. Biological mesh was associated with reduced reconstruction-related morbidity compared with perineal flaps. Further validation in additional cohorts is required to address potential confounding factors.
盆腔切除术(PE)是一种治疗晚期盆腔癌的潜在治疗方法。然而,PE手术与骨盆空综合征(EPS)相关,包括骨盆败血症、窦形成、瘘管和肠梗阻等一系列并发症。不一致的报告阻碍了对每股收益的理解。PelvEx协作引入了一个描述符和结果的核心数据集来解决这些问题,本研究的目的是验证该数据集。方法一项观察性队列研究将EPS核心数据集应用于前瞻性维护的PE数据库。评估主要和次要表现的模式;使用逻辑回归来探索描述符与结果之间的关系,并使用Cramer's v评估描述符间的相关性。结果327例患者中有105例发生了tsps,是主要发病的主要原因。感染盆腔积液(23.5%)与随后的慢性窦形成(OR 3.08, P = 0.01)和瘘管(P = 0.05)相关。外束放疗(OR 1.01 / 1gy, P = 0.01)、骶骨切除术(OR 3.78, P < 0.001)、全膀胱切除术(OR 2.46, P = 0.001)、髂内血管结扎(OR 1.94, P = 0.045;双侧OR 3.65, P < 0.001)和提下肌拔出(OR 3.69, P < 0.001)。网膜成形术减少盆腔肠梗阻(OR 0.27, P = 0.004)和会阴皮瓣与单独使用生物补片相比,与重建相关的主要发病率更高(20.8%对1.2%,P = 0.002)。结论:PelvEx协作核心数据集标准化了EPS的报告,该研究详细说明了由此引起的急性和慢性并发症。与会阴皮瓣相比,生物补片可降低重建相关的发病率。需要在其他队列中进一步验证以解决潜在的混杂因素。
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引用次数: 0
Obesity is more than a number: a framework for treatment. 肥胖不仅仅是一个数字,而是一个治疗框架。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf100
Ricardo V Cohen,Gerhard Prager,Paulina Salminen
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引用次数: 0
Three-year patient-reported outcomes of the BOOG 2013-08 RCT evaluating omission of sentinel lymph node biopsy in early-stage breast cancer patients treated with breast conserving surgery: Impact of personality traits on health-related quality of life. BOOG 2013-08随机对照试验评估早期乳腺癌保乳手术患者遗漏前哨淋巴结活检的三年患者报告结果:人格特质对健康相关生活质量的影响
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf031
Veerle M Wintraecken,Lori M van Roozendaal,Janine M Simons,Jolanda de Vries,Sander M J van Kuijk,Marissa L G Vane,Thijs van Dalen,Helena Sackey,Jos A van der Hage,Luc J A Strobbe,Sabine C Linn,Marc B I Lobbes,Philip M P Poortmans,Vivianne C G Tjan-Heijnen,Koen K B T van de Vijver,Helen H Westenberg,Carmen D Dirksen,Johan H W de Wilt,Liesbeth J Boersma,Marjolein L Smidt
BACKGROUNDThe non-inferiority randomized controlled trial BOOG 2013-08 investigates the oncological safety and impact on health-related quality of life (HRQoL) of sentinel lymph node biopsy (SNLB) omission in cT1-2 N0 breast cancer. The primary aim of the present study was to compare patient-reported arm function and HRQoL up to 3 years after study inclusion in cT1-2 N0 patients with breast cancer undergoing breast-conserving surgery (BCS) with or without SLNB. The secondary aim was to explore the association between personality traits 'trait anxiety' and 'neuroticism', and perceived arm function and HRQoL.METHODSA total of 1733 women with unilateral cT1-2 N0 invasive breast cancer treated with BCS with or without SLNB were included. The primary outcomes of arm function (assessed using the Lymphoedema Functioning, Disability, and Health Questionnaire) and HRQoL (assessed using the European Organisation for Research and Treatment of Cancer QLQ-C30 and QLQ-BR-23 questionnaires) were analysed.RESULTSAnalyses included 821 patients (383 with SLNB and 438 without SLNB). Those in the SLNB group experienced a slight, temporary decline in arm function (P < 0.025) and reported more HRQoL arm and breast symptoms (P < 0.049). High trait anxiety or neuroticism was associated with significant poorer arm function and lower HRQoL.CONCLUSIONSLNB slightly reduced arm function, temporarily affecting HRQoL arm and breast symptoms. Neuroticism significantly negatively impacted arm function and HRQoL. Measuring and stratifying for personality traits is crucial for interpreting patient-reported outcomes and to identify patients needing additional support after surgery.REGISTRATION NUMBERNCT02271828 (http://www.clinicaltrials.gov).
背景:BOOG 2013-08非效性随机对照试验调查了cT1-2 N0乳腺癌前哨淋巴结活检(SNLB)遗漏的肿瘤安全性和对健康相关生活质量(HRQoL)的影响。本研究的主要目的是比较cT1-2 N0乳腺癌患者接受保乳手术(BCS)伴或不伴SLNB后3年患者报告的手臂功能和HRQoL。第二个目的是探索人格特征“特质焦虑”和“神经质”之间的关系,以及感知手臂功能和HRQoL之间的关系。方法共纳入1733例单侧cT1-2 N0浸润性乳腺癌患者,BCS合并或不合并SLNB。对手臂功能(使用淋巴水肿功能、残疾和健康问卷进行评估)和HRQoL(使用欧洲癌症研究和治疗组织QLQ-C30和QLQ-BR-23问卷进行评估)的主要结果进行分析。结果共纳入821例患者,其中383例合并SLNB, 438例未合并SLNB。SLNB组的患者出现了轻微的、暂时的手臂功能下降(P < 0.025),并且报告了更多的HRQoL手臂和乳房症状(P < 0.049)。高特质焦虑或神经质与明显较差的手臂功能和较低的HRQoL相关。结论:slnb轻度降低手臂功能,暂时影响HRQoL手臂和乳房症状。神经质对手臂功能和HRQoL有显著负向影响。人格特征的测量和分层对于解释患者报告的结果和确定术后需要额外支持的患者至关重要。注册号:02271828 (http://www.clinicaltrials.gov)。
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引用次数: 0
Correction to: Endovascular treatment of peripheral arterial disease: Endo-STAR framework for the design, conduct, and reporting of trials. 外周动脉疾病的血管内治疗:试验设计、实施和报告的Endo-STAR框架。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf105
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引用次数: 0
Beyond the operating room: surgeons' perceptions of the environmental footprint of the healthcare sector. 手术室之外:外科医生对医疗保健行业环境足迹的看法。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf088
Russell S Martins,Warda Ahmed,M Umar Mahar,Ayilkin Çelik,Jeffrey Luo,Syed S Razi,Kostantinos Poulikidis,M Jawad Latif,Kyle Tafuri,Mahim A Malik,Faiz Y Bhora,
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引用次数: 0
Sigmoid volvulus: outcomes of surgery and conservative management after initial colonoscopic decompression (the VOLVUCOL study). 乙状结肠扭转:初始结肠镜减压后手术和保守治疗的结果(VOLVUCOL研究)。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf085
Lucie Audeguy,Mattia Stella,Damien Duprez,Astrid Laurent,Fatah Tidadini,Alison Foote,Joey Fournier,Bertrand Trilling,Jean-Luc Faucheron
{"title":"Sigmoid volvulus: outcomes of surgery and conservative management after initial colonoscopic decompression (the VOLVUCOL study).","authors":"Lucie Audeguy,Mattia Stella,Damien Duprez,Astrid Laurent,Fatah Tidadini,Alison Foote,Joey Fournier,Bertrand Trilling,Jean-Luc Faucheron","doi":"10.1093/bjs/znaf085","DOIUrl":"https://doi.org/10.1093/bjs/znaf085","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"109 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of revision surgery after implant-based breast reconstruction between smooth, textured, and polyurethane-covered implants: results from the Dutch Breast Implant Registry. 光滑的、有纹理的和聚氨酯覆盖的假体乳房重建后修复手术的比较:来自荷兰乳房假体注册中心的结果。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf082
J Xavier Harmeling,J Juliët Vrolijk,Erik Heeg,Babette E Becherer,Hinne A Rakhorst,Eveline M L Corten,Marta Fiocco,Marc A M Mureau
BACKGROUNDImplant-based breast reconstruction is the most common technique after mastectomy. Breast implants are categorized by surface type as smooth, textured, or polyurethane-covered, each with specific attributed advantages and complication profiles. High-quality comparative studies are, however, limited. This study compared revision incidence and indications for revision among these implant types.METHODSA prospective, nationwide cohort from the Dutch Breast Implant Registry was analysed. Permanent implants used between 2017 and 2022 for direct-to-implant or two-stage reconstruction were included. Surface-related revision was the primary outcome. Cumulative incidences were estimated using a competing risk model. Cause-specific hazard ratios (HRcs) were calculated using univariable and multivariable models, accounting for implant clustering and confounders. Subgroup analyses examined revisions for specific complications.RESULTSOf 3996 implants, 76.9% were textured, 12.4% smooth, and 10.8% polyurethane-covered. At 4 years, the cumulative incidence of revision surgeries did not differ between textured (11.1%; 95% c.i. = 9.9 to 12.5), smooth (13.0%; 95% c.i. = 8.5 to 18.4), and polyurethane-covered (16.1%; 95% c.i. = 12.4 to 20.2) implants. Multivariable analysis found no association between surface type and surface-related revision. Subgroup analysis however revealed that polyurethane-covered implants had increased hazards of revision for capsular contracture (HRcs = 2.49; 95% c.i. = 1.24 to 5.01) and asymmetry (HRcs = 2.31; 95% c.i. = 1.33 to 4.02).CONCLUSIONAfter adjusting for confounders and clustering, surface-related revision in a reconstructive setting did not significantly different among breast implant surface types overall. Polyurethane-covered implants may, however, require more revisions due to capsular contracture and asymmetry.
背景:植体乳房重建是乳房切除术后最常见的技术。乳房植入物按表面类型分为光滑,有纹理或聚氨酯覆盖,每种都具有特定的优点和并发症概况。然而,高质量的比较研究是有限的。本研究比较了这些种植体类型的翻修发生率和翻修适应症。方法对来自荷兰乳房植入物注册中心的前瞻性全国队列进行分析。包括2017年至2022年间用于直接种植体或两阶段重建的永久种植体。表面相关修复是主要结果。使用竞争风险模型估计累积发生率。使用单变量和多变量模型计算原因特异性风险比(HRcs),考虑植入物聚类和混杂因素。亚组分析检查了针对特定并发症的修订。结果3996个种植体中,76.9%有纹理,12.4%光滑,10.8%聚氨酯覆盖。在4年的时间里,修复手术的累积发生率在纹理(11.1%;95% ci = 9.9 ~ 12.5),平滑(13.0%;95% c.i. = 8.5至18.4),聚氨酯覆盖(16.1%;95% c.i. = 12.4 ~ 20.2)种植体。多变量分析发现表面类型和表面相关修正之间没有关联。然而,亚组分析显示聚氨酯覆盖种植体增加了包膜挛缩翻修的危险(HRcs = 2.49;95% ci = 1.24 ~ 5.01)和不对称(HRcs = 2.31;95% ci = 1.33 ~ 4.02)。结论:在调整混杂因素和聚类因素后,乳房植入物表面类型在重建环境中的表面相关翻修总体上没有显著差异。然而,由于包膜挛缩和不对称,聚氨酯覆盖的植入物可能需要更多的修正。
{"title":"Comparison of revision surgery after implant-based breast reconstruction between smooth, textured, and polyurethane-covered implants: results from the Dutch Breast Implant Registry.","authors":"J Xavier Harmeling,J Juliët Vrolijk,Erik Heeg,Babette E Becherer,Hinne A Rakhorst,Eveline M L Corten,Marta Fiocco,Marc A M Mureau","doi":"10.1093/bjs/znaf082","DOIUrl":"https://doi.org/10.1093/bjs/znaf082","url":null,"abstract":"BACKGROUNDImplant-based breast reconstruction is the most common technique after mastectomy. Breast implants are categorized by surface type as smooth, textured, or polyurethane-covered, each with specific attributed advantages and complication profiles. High-quality comparative studies are, however, limited. This study compared revision incidence and indications for revision among these implant types.METHODSA prospective, nationwide cohort from the Dutch Breast Implant Registry was analysed. Permanent implants used between 2017 and 2022 for direct-to-implant or two-stage reconstruction were included. Surface-related revision was the primary outcome. Cumulative incidences were estimated using a competing risk model. Cause-specific hazard ratios (HRcs) were calculated using univariable and multivariable models, accounting for implant clustering and confounders. Subgroup analyses examined revisions for specific complications.RESULTSOf 3996 implants, 76.9% were textured, 12.4% smooth, and 10.8% polyurethane-covered. At 4 years, the cumulative incidence of revision surgeries did not differ between textured (11.1%; 95% c.i. = 9.9 to 12.5), smooth (13.0%; 95% c.i. = 8.5 to 18.4), and polyurethane-covered (16.1%; 95% c.i. = 12.4 to 20.2) implants. Multivariable analysis found no association between surface type and surface-related revision. Subgroup analysis however revealed that polyurethane-covered implants had increased hazards of revision for capsular contracture (HRcs = 2.49; 95% c.i. = 1.24 to 5.01) and asymmetry (HRcs = 2.31; 95% c.i. = 1.33 to 4.02).CONCLUSIONAfter adjusting for confounders and clustering, surface-related revision in a reconstructive setting did not significantly different among breast implant surface types overall. Polyurethane-covered implants may, however, require more revisions due to capsular contracture and asymmetry.","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"58 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Round ligament coverage with polyglycol acid mesh and fibrin glue on pancreatic stump may decrease postoperative pancreatic fistula in distal pancreatectomy. 聚乙二醇酸网和纤维蛋白胶覆盖胰腺残端圆形韧带可减少远端胰腺切除术后胰瘘。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf101
Yuki Adachi,Hirohisa Okabe,Hiromitsu Hayashi,Yoshiyuki Tagayasu,Takumi Tanizaki,Shinsei Yumoto,Kosuke Kanemitsu,Takuya Tajiri,Daisuke Ogawa,Rumi Itoyama,Yuki Kitano,Shigeki Nakagawa,Hidetoshi Nitta,Toshiro Masuda,Hiroki Sugita,Masaaki Iwatsuki
{"title":"Round ligament coverage with polyglycol acid mesh and fibrin glue on pancreatic stump may decrease postoperative pancreatic fistula in distal pancreatectomy.","authors":"Yuki Adachi,Hirohisa Okabe,Hiromitsu Hayashi,Yoshiyuki Tagayasu,Takumi Tanizaki,Shinsei Yumoto,Kosuke Kanemitsu,Takuya Tajiri,Daisuke Ogawa,Rumi Itoyama,Yuki Kitano,Shigeki Nakagawa,Hidetoshi Nitta,Toshiro Masuda,Hiroki Sugita,Masaaki Iwatsuki","doi":"10.1093/bjs/znaf101","DOIUrl":"https://doi.org/10.1093/bjs/znaf101","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"9 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementing laparoscopic liver surgery in Sub-Saharan Africa: a capacity-building and hepatopancreatobiliary mentorship model. 在撒哈拉以南非洲实施腹腔镜肝脏手术:能力建设和肝胆胰指导模式。
IF 8.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znaf107
Victor Lopez-Lopez, Abdi Hakin Mohamed, Asunción López-Conesa, David Fernández, Mercedes Benítez, Ricardo Robles-Campos, Ramadhani Omari Abdalla, Jose Manuel Rodriguez
{"title":"Implementing laparoscopic liver surgery in Sub-Saharan Africa: a capacity-building and hepatopancreatobiliary mentorship model.","authors":"Victor Lopez-Lopez, Abdi Hakin Mohamed, Asunción López-Conesa, David Fernández, Mercedes Benítez, Ricardo Robles-Campos, Ramadhani Omari Abdalla, Jose Manuel Rodriguez","doi":"10.1093/bjs/znaf107","DOIUrl":"https://doi.org/10.1093/bjs/znaf107","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144126325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Consensus classification of biliary complications after liver transplantation: guidelines from the BileducTx meeting. 肝移植术后胆道并发症的共识分类:BileducTx会议指南。
IF 9.6 1区 医学 Q1 SURGERY Pub Date : 2025-04-30 DOI: 10.1093/bjs/znae321
Hannah Esser,Iris E M de Jong,Floris M Roos,Christina Bogensperger,Stefan M Brunner,Benno Cardini,Philipp Dutkowski,Hasan Eker,Sofia Ferreira-Gonzalez,Stuart J Forbes,Peter J Friend,Yiliam Fundora,Henrik Junger,Felix J Krendl,Paulo N Martins,Vincent E de Meijer,Rupert Oberhuber,Gabriel C Oniscu,Damiano Patrono,Robert J Porte,Thomas Resch,Hatem Sadik,Andrea Schlegel,Nicola De Stefano,Mathias Vidgren,Christopher J E Watson,Annemarie Weißenbacher,Stefan Schneeberger
{"title":"Consensus classification of biliary complications after liver transplantation: guidelines from the BileducTx meeting.","authors":"Hannah Esser,Iris E M de Jong,Floris M Roos,Christina Bogensperger,Stefan M Brunner,Benno Cardini,Philipp Dutkowski,Hasan Eker,Sofia Ferreira-Gonzalez,Stuart J Forbes,Peter J Friend,Yiliam Fundora,Henrik Junger,Felix J Krendl,Paulo N Martins,Vincent E de Meijer,Rupert Oberhuber,Gabriel C Oniscu,Damiano Patrono,Robert J Porte,Thomas Resch,Hatem Sadik,Andrea Schlegel,Nicola De Stefano,Mathias Vidgren,Christopher J E Watson,Annemarie Weißenbacher,Stefan Schneeberger","doi":"10.1093/bjs/znae321","DOIUrl":"https://doi.org/10.1093/bjs/znae321","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"55 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
British Journal of Surgery
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