Sander J M van Hootegem,Niels A D Guchelaar,Karen van der Sluis,Lianne Triemstra,Stefan P Mönig,Karol Rawicz-Pruszyński,Riccardo Rosati,Paolo Morgagni,Maria Erodotou,Leonardo Solaini,Giovanni De Manzoni,Wojciech Polkowski,Francesco Puccetti,Simone Giacopuzzi,Suzanne S Gisbertz,Jimmy B Y So,Jelle P Ruurda,Pieter S L van der Sluis,Sjoerd M Lagarde,Johanna W van Sandick,Bas P L Wijnhoven,
{"title":"Staging laparoscopy for gastric cancer: European consensus.","authors":"Sander J M van Hootegem,Niels A D Guchelaar,Karen van der Sluis,Lianne Triemstra,Stefan P Mönig,Karol Rawicz-Pruszyński,Riccardo Rosati,Paolo Morgagni,Maria Erodotou,Leonardo Solaini,Giovanni De Manzoni,Wojciech Polkowski,Francesco Puccetti,Simone Giacopuzzi,Suzanne S Gisbertz,Jimmy B Y So,Jelle P Ruurda,Pieter S L van der Sluis,Sjoerd M Lagarde,Johanna W van Sandick,Bas P L Wijnhoven, ","doi":"10.1093/bjs/znaf144","DOIUrl":"https://doi.org/10.1093/bjs/znaf144","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"15 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144995875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges of decision-making after treatment with immunotherapy in metastatic deficient DNA mismatch repair/microsatellite unstable colorectal cancer.","authors":"Julien Taieb,Mehdi Karoui","doi":"10.1093/bjs/znaf178","DOIUrl":"https://doi.org/10.1093/bjs/znaf178","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"163 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Chatbot Assessment Reporting Tool (CHART) is a reporting guideline developed to provide reporting recommendations for studies evaluating the performance of generative artificial intelligence (AI)-driven chatbots when summarizing clinical evidence and providing health advice, referred to as chatbot health advice studies. CHART was developed in several phases after performing a comprehensive systematic review to identify variation in the conduct, reporting, and method in chatbot health advice studies. Findings from the review were used to develop a draft checklist that was revised through an international, multidisciplinary, modified, asynchronous Delphi consensus process of 531 stakeholders, three synchronous panel consensus meetings of 48 stakeholders, and subsequent pilot testing of the checklist. CHART includes 12 items and 39 subitems to promote transparent and comprehensive reporting of chatbot health advice studies. These include title (subitem 1a), abstract/summary (subitem 1b), background (subitems 2a,b), model identifiers (subitems 3a,b), model details (subitems 4a-c), prompt engineering (subitems 5a,b), query strategy (subitems 6a-d), performance evaluation (subitems 7a,b), sample size (subitem 8), data analysis subitem 9a), results (subitems 10a-c), discussion (subitems 11a-c), disclosures (subitem 12a), funding (subitem 12b), ethics (subitem 12c), protocol (subitem 12d), and data availability (subitem 12e). The CHART checklist and corresponding diagram of the method were designed to support key stakeholders including clinicians, researchers, editors, peer reviewers, and readers in reporting, understanding, and interpreting the findings of chatbot health advice studies.
{"title":"Reporting guideline for chatbot health advice studies: the Chatbot Assessment Reporting Tool (CHART) statement.","authors":" ","doi":"10.1093/bjs/znaf142","DOIUrl":"https://doi.org/10.1093/bjs/znaf142","url":null,"abstract":"The Chatbot Assessment Reporting Tool (CHART) is a reporting guideline developed to provide reporting recommendations for studies evaluating the performance of generative artificial intelligence (AI)-driven chatbots when summarizing clinical evidence and providing health advice, referred to as chatbot health advice studies. CHART was developed in several phases after performing a comprehensive systematic review to identify variation in the conduct, reporting, and method in chatbot health advice studies. Findings from the review were used to develop a draft checklist that was revised through an international, multidisciplinary, modified, asynchronous Delphi consensus process of 531 stakeholders, three synchronous panel consensus meetings of 48 stakeholders, and subsequent pilot testing of the checklist. CHART includes 12 items and 39 subitems to promote transparent and comprehensive reporting of chatbot health advice studies. These include title (subitem 1a), abstract/summary (subitem 1b), background (subitems 2a,b), model identifiers (subitems 3a,b), model details (subitems 4a-c), prompt engineering (subitems 5a,b), query strategy (subitems 6a-d), performance evaluation (subitems 7a,b), sample size (subitem 8), data analysis subitem 9a), results (subitems 10a-c), discussion (subitems 11a-c), disclosures (subitem 12a), funding (subitem 12b), ethics (subitem 12c), protocol (subitem 12d), and data availability (subitem 12e). The CHART checklist and corresponding diagram of the method were designed to support key stakeholders including clinicians, researchers, editors, peer reviewers, and readers in reporting, understanding, and interpreting the findings of chatbot health advice studies.","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"16 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144756184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Protocol for the GOLF trial: randomized clinical trial on the LINX management system versus fundoplication for the surgical treatment of gastro-oesophageal reflux disease.","authors":"Sheraz R Markar,Begum Zeybek Saglam,Nainika Menon,Ahmed Ahmed,Nick Maynard,James Gossage,Filipa Landeiro,Jane Blazeby,Nicola Mills,Tim Underwood,Mimi McCord,T Martyn Hill,Amy Taylor,Natalie Blencowe,Jesper Lagergren","doi":"10.1093/bjs/znaf141","DOIUrl":"https://doi.org/10.1093/bjs/znaf141","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"23 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144612878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hila Zelicha,Douglas S Bell,Yijun Chen,Edward H Livingston
{"title":"Potential for error when relying on administrative data.","authors":"Hila Zelicha,Douglas S Bell,Yijun Chen,Edward H Livingston","doi":"10.1093/bjs/znaf139","DOIUrl":"https://doi.org/10.1093/bjs/znaf139","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"10 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144645910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scaling the impact of surgical complications.","authors":"Oleksandr Khoma,Jerome Laurence,Bas Wijnhoven","doi":"10.1093/bjs/znaf145","DOIUrl":"https://doi.org/10.1093/bjs/znaf145","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"13 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144612877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BACKGROUNDSentinel lymph node (SLN) staging is essential in breast cancer. Superparamagnetic iron oxide nanoparticles (SPIO) is a tracer where the optimal injection technique is yet not defined. The aim was to evaluate SLN detection using 0.1 ml SPIO intradermally compared to technetium-99 m (Tc99) ± blue dye.METHODPatients planned for breast surgery and SLN biopsy received 0.1 ml SPIO intradermally at the areolar border or over the tumour. Tc99 ± blue dye was administered per clinical routine. Magnetic, radioactive, or blue nodes were removed and analysed separately. SLN detection and numbers, concordance, and skin discoloration were analysed.RESULTSA total of 216 patients were included at five hospitals. Median age was 63 years, tumour size 15.9 mm, and 91.7% underwent breast conservation. SPIO was injected a median of 12 days before surgery. SLN detection was 211/216 (97.7%; 95% c.i.: 94.7 to 99.2) and 215/216 (99.5%; 95% c.i.: 98.6 to 100.0) for SPIO and Tc99 ± blue dye (P = 0.111) respectively. In total, 403 SLNs were removed; 341 detected by SPIO and 349 by Tc99 ± blue dye. The median number of SLNs was 1 (iqr: 1-2) for both tracer methods. Among 46 SLN-positive patients, 42 were correctly staged with both tracers, two with SPIO only and two with Tc99 ± blue dye only. Skin discoloration was evaluated in 107 patients. The median discoloured area was 0 cm2 (iqr: 0-0.7) among 49 patients with the injection site surgically removed and 1.3 cm2 (iqr: 0.6-2.8) among 58 without removal.CONCLUSIONAn ultra-low dose of 0.1 ml intradermal injection of SPIO was non-inferior to Tc99 ± blue dye for SLN detection. Skin discoloration was limited and further reduced by removal during surgery.
{"title":"Ultra-low dose superparamagnetic iron oxide nanoparticle injection for sentinel lymph node detection in breast cancer: prospective cohort study.","authors":"Lovisa Sundh,Marya Alzoubi,Nizar Abu-Oddos,Sarah Båtelsson,Per Nyman,Andreas Karakatsanis,Staffan Eriksson,Mookaiah Ravichandran,Kian Chin,Roger Olofsson Bagge,Nushin Mirzaei,Fredrik Wärnberg","doi":"10.1093/bjs/znaf129","DOIUrl":"https://doi.org/10.1093/bjs/znaf129","url":null,"abstract":"BACKGROUNDSentinel lymph node (SLN) staging is essential in breast cancer. Superparamagnetic iron oxide nanoparticles (SPIO) is a tracer where the optimal injection technique is yet not defined. The aim was to evaluate SLN detection using 0.1 ml SPIO intradermally compared to technetium-99 m (Tc99) ± blue dye.METHODPatients planned for breast surgery and SLN biopsy received 0.1 ml SPIO intradermally at the areolar border or over the tumour. Tc99 ± blue dye was administered per clinical routine. Magnetic, radioactive, or blue nodes were removed and analysed separately. SLN detection and numbers, concordance, and skin discoloration were analysed.RESULTSA total of 216 patients were included at five hospitals. Median age was 63 years, tumour size 15.9 mm, and 91.7% underwent breast conservation. SPIO was injected a median of 12 days before surgery. SLN detection was 211/216 (97.7%; 95% c.i.: 94.7 to 99.2) and 215/216 (99.5%; 95% c.i.: 98.6 to 100.0) for SPIO and Tc99 ± blue dye (P = 0.111) respectively. In total, 403 SLNs were removed; 341 detected by SPIO and 349 by Tc99 ± blue dye. The median number of SLNs was 1 (iqr: 1-2) for both tracer methods. Among 46 SLN-positive patients, 42 were correctly staged with both tracers, two with SPIO only and two with Tc99 ± blue dye only. Skin discoloration was evaluated in 107 patients. The median discoloured area was 0 cm2 (iqr: 0-0.7) among 49 patients with the injection site surgically removed and 1.3 cm2 (iqr: 0.6-2.8) among 58 without removal.CONCLUSIONAn ultra-low dose of 0.1 ml intradermal injection of SPIO was non-inferior to Tc99 ± blue dye for SLN detection. Skin discoloration was limited and further reduced by removal during surgery.","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"52 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144684168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas F Stoop,Ingmar F Rompen,Mahsoem Ali,Bas Groot Koerkamp,Bert A Bonsing,Jan Willem B de Groot,Geert A Cirkel,Hjalmar C van Santvoort,Inez M Verpalen,I Quintus Molenaar,Johanna W Wilmink,Judith de Vos-Geelen,Lois A Daamen,Marc R W Engelbrecht,Marjolein Y V Homs,Martijn P W Intven,Martijn W J Stommel,Vincent E de Meijer,Lydia G van der Geest,Marc G Besselink,
{"title":"Resectability stages of pancreatic cancer: nationwide reference.","authors":"Thomas F Stoop,Ingmar F Rompen,Mahsoem Ali,Bas Groot Koerkamp,Bert A Bonsing,Jan Willem B de Groot,Geert A Cirkel,Hjalmar C van Santvoort,Inez M Verpalen,I Quintus Molenaar,Johanna W Wilmink,Judith de Vos-Geelen,Lois A Daamen,Marc R W Engelbrecht,Marjolein Y V Homs,Martijn P W Intven,Martijn W J Stommel,Vincent E de Meijer,Lydia G van der Geest,Marc G Besselink, ","doi":"10.1093/bjs/znaf120","DOIUrl":"https://doi.org/10.1093/bjs/znaf120","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"23 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: EGS SO28 - Management of oesophageal diverticulitis in a 71-year-old female: Case report and review of management approaches.","authors":"","doi":"10.1093/bjs/znaf165","DOIUrl":"10.1093/bjs/znaf165","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 7","pages":""},"PeriodicalIF":8.8,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144726193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Deffrennes,Serena MacMillan,Anna Paterson,Michael L Nicholson,Sarah A Hosgood
{"title":"Subnormothermic acellular machine perfusion for prolonged preservation of human kidneys.","authors":"Sara Deffrennes,Serena MacMillan,Anna Paterson,Michael L Nicholson,Sarah A Hosgood","doi":"10.1093/bjs/znaf147","DOIUrl":"https://doi.org/10.1093/bjs/znaf147","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"44 4 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144684289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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