International dental journal最新文献

{"title":"Clinical, Immunological and Microbiological Improvements With Zinc-Coated Healing Abutments During the Healing Phase","authors":"Yu Zhu ,&nbsp;Shu-li Liu ,&nbsp;Xiong Lu ,&nbsp;Gang Luo ,&nbsp;Zuo-hui Xiao ,&nbsp;Ying-kai Wang ,&nbsp;Jie Zhou ,&nbsp;Shi-chong Qiao","doi":"10.1016/j.identj.2025.109338","DOIUrl":"10.1016/j.identj.2025.109338","url":null,"abstract":"<div><h3>Purpose</h3><div>The aim of this study was to evaluate the clinical, immunological, and microbiological effects of zinc-coated healing abutments (Zn-TiO₂ abutments) on peri-implant soft tissue as compared with the commercially used ones (Ti abutments).</div></div><div><h3>Methods</h3><div>The study was a prospective, non-randomised, single-centre, open-label, proof-of-concept clinical trial. The Ti and Zn-TiO₂ abutments were non-randomly connected to 2 neighbouring implants in the posterior region in each eligible patient. The bleeding-on-probing proportion (BOP%), probing pocket depth (PPD), the concentration of the pro-inflammatory cytokine (TNF-α, IL-6) in the peri-implant crevicular fluid (PICF), and the early microbial communities assessed by 16S rRNA sequencing were recorded.</div></div><div><h3>Results</h3><div>Eleven patients with 22 implants attended the 8-week examination. The BOP% was significantly lower in the Zn-TiO₂ abutments than that in the Ti abutments (24.23% ± 13.67% versus 42.42% ± 29.22%, <em>P</em> = .019). The concentration of TNF-α in PICF was significantly lower in the Zn-TiO₂ abutments than that in the Ti abutments (22.86 ± 11.21 versus 32.05 ± 16.28, <em>P</em> = .022). No significant differences in PPD and IL-6 were found between the two groups. Based on the microbiome assessments, higher microbial richness and lower presence of <em>Lancefieldella</em> were also observed in the Zn-TiO₂ abutments as compared with the Ti abutments.</div></div><div><h3>Conclusion</h3><div>Within the limitations of the study, the zinc-coated healing abutments improved early peri-implant soft tissue health clinically and immunologically. However, further studies are still needed to exclude the interference of soft tissue phenotype and confirm the relationship between microbial and clinical findings.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109338"},"PeriodicalIF":3.7,"publicationDate":"2026-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Sodium Fluoride Safety Signals: Dual-Database Pharmacovigilance","authors":"Wanchen Ning ,&nbsp;Xiangyu Huang ,&nbsp;Simin Li ,&nbsp;Linxin Jiang ,&nbsp;Daniel R Reissmann ,&nbsp;Deborah Kreher ,&nbsp;Gerhard Schmalz ,&nbsp;Lei Chen ,&nbsp;Shaohong Huang","doi":"10.1016/j.identj.2026.109423","DOIUrl":"10.1016/j.identj.2026.109423","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Sodium fluoride is widely used in preventive dentistry, yet its global safety profile has not been comprehensively characterised using real-world data. This study aimed to characterise reporting patterns and safety signals associated with sodium fluoride through an integrated pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) and the World Health Organization (WHO) VigiBase.</div></div><div><h3>Methods</h3><div>Adverse event (AE) reports related to sodium fluoride were extracted from FAERS (2004-2024) and VigiBase (1971-2024). Reporting characteristics, including demographic distributions, reporter type, and event seriousness, were summarised descriptively. AEs were coded using the medical dictionary for regulatory activities (MedDRA) at the preferred term (PT) and system organ class (SOC) levels. Disproportionality-based signal detection was performed using multiple algorithms, and cross-database validation was applied to evaluate signal consistency and database-specific reporting features.</div></div><div><h3>Results</h3><div>Reporting patterns differed between the two systems: FAERS reports were predominantly submitted from the United States and by consumers, whereas VigiBase reports were mainly from Europe, with a higher proportion of health care professionals reporting. Reports involving female individuals were more frequently observed in both databases. Safety signals were primarily concentrated in oral and dental conditions, including dental fluorosis and acute oral mucosal reactions. Overall, 122 shared safety signals were identified across the two databases, with 62% involving oral or dental tissues. Adult populations accounted for a substantial proportion of reported signals, and a high proportion of reports were classified as serious, with predominantly early reported onset intervals.</div></div><div><h3>Conclusion</h3><div>This dual-database pharmacovigilance analysis identified consistent sodium fluoride-associated safety signals with a predominant oral and dental focus, alongside notable geographic and demographic reporting differences. Cross-database validation highlighted complementary strengths of FAERS and VigiBase for global safety surveillance of fluoride-containing dental products.</div></div><div><h3>Clinical relevance</h3><div>These findings support enhanced awareness of sodium fluoride-related safety patterns and may inform targeted monitoring strategies in preventive dental practice.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109423"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long Noncoding RNA SATB1-AS1 Suppresses Inflammatory Response and Injury in Dental Pulp Stem Cells Through the miR-15a-5p/E2F3 Axis","authors":"Shuyue Ding ,&nbsp;Yuan Shi","doi":"10.1016/j.identj.2026.109412","DOIUrl":"10.1016/j.identj.2026.109412","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Pulpitis represents a prevalent dental condition where inflammatory tissue damage can advance into irreversible stages or pulp death, ultimately compromising oral health-related quality of life. This study investigated the role and underlying mechanisms of long noncoding RNA SATB1-AS1 in pulpitis progression, offering potential therapeutic targets for this condition.</div></div><div><h3>Methods</h3><div>This study included 50 patients with irreversible pulpitis (pulpitis group) and 50 age- and gender-matched orthodontic extraction controls (control group). The expression of SATB1-AS1 in pulpitis tissues was assayed using real-time quantitative PCR. A pulpitis model was established by treating human dental pulp stem cells (DPSCs) with lipopolysaccharide (LPS). Evaluation of DPSC proliferation was performed using CCK-8. The levels of cell cycle-related proteins and inflammatory factors were measured by ELISA, and oxidative stress was evaluated by detecting superoxide dismutase, glutathione peroxidase, glutathione, and malondialdehyde. Bioinformatics tools were utilized to identify potential targets, followed by experimental validation through dual-luciferase reporter assays.</div></div><div><h3>Results</h3><div>Downregulation of SATB1-AS1 was identified in diseased pulpitis tissues and cell models. In LPS-induced DPSCs, SATB1-AS1 facilitated cell proliferation and modulated Cyclin D1 and p21 expression. Furthermore, SATB1-AS1 alleviated the LPS-induced release of IL-1β, IL-6, and IL-8, and mitigated oxidative stress-related injury by altering the levels of superoxide dismutase, glutathione peroxidase, glutathione, and malondialdehyde. MiR-15a-5p was negatively modulated by SATB1-AS1. Concurrent expression of miR-15a-5p eliminated the beneficial effects of SATB1-AS1 on DPSC function. Further investigation identified E2F3 as a target of miR-15a-5p, establishing the SATB1-AS1/miR-15a-5p/E2F3 axis as a regulatory pathway in LPS-treated DPSCs.</div></div><div><h3>Conclusion</h3><div>The findings indicate that SATB1-AS1 potentially mitigates inflammatory processes and oxidative damage via modulation of the miR-15a-5p/E2F3 axis, consequently suppressing pulpitis development.</div></div><div><h3>Clinical relevance</h3><div>This study suggests that SATB1-AS1 may serve as a novel diagnostic biomarker and therapeutic target for pulpitis, providing a potential strategy to preserve pulp vitality and improve clinical outcomes.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109412"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developing an Interpretable Machine Learning Framework to Predict and Analyse Early Childhood Caries in Children Aged 2 to 6 Years: A Single-centre Observational Study","authors":"Xinyue Yuan,&nbsp;Yiting Chu,&nbsp;Wenyan Cai","doi":"10.1016/j.identj.2026.109419","DOIUrl":"10.1016/j.identj.2026.109419","url":null,"abstract":"<div><h3>Background</h3><div>Early childhood caries (ECC) is a prevalent global oral health condition, exerting profound adverse effects on children’s oral health, general health, and quality of life. Its onset involves demographic, socioeconomic, behavioural, and clinical factors. While many studies report individual risks, systematic analyses to prioritise predictors remain limited.</div></div><div><h3>Methods</h3><div>This single-centre observational study included 900 children who visited the hospital between October 2022 and May 2024. Collected variables included age, parental background, feeding practices, general health status, oral hygiene and dietary habits. Univariate and multivariate analyses were conducted to identify factors associated with ECC. Five machine learning (ML) models – logistic regression (LR), random forest (RF), decision tree (DT), k-nearest neighbours (KNN) and support vector machine (SVM) – were developed to predict ECC. ECC presence or absence was used as the clinical outcome. Risk stratification classified children into low-, moderate-, and high-risk groups.</div></div><div><h3>Results</h3><div>Significant predictors included age, maternal education, vitamin supplementation during pregnancy and for the child, carbohydrate intake, nighttime feeding behaviours, cessation timing, light exposure during sleep and outdoor activity (<em>P</em> &lt; .05). LR achieved the highest accuracy (99.4%), followed by SVM (98.9%), RF (96.7%), DT (95.0%) and KNN (91.1%).</div></div><div><h3>Conclusion</h3><div>The machine learning models effectively identified key determinants of ECC, underscoring the critical roles of maternal education, dietary patterns, and lifestyle-related factors. Risk-based stratification derived from these models may inform targeted early preventive interventions in both clinical and community settings, thereby contributing to a reduction in the overall burden of ECC.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109419"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multimodal Model for Caries Screening Using Intraoral Images and Questionnaires","authors":"Zhuoying Liu ,&nbsp;Junjie Li ,&nbsp;Siwei Wang ,&nbsp;Weijia Liu ,&nbsp;Wenyu Wang ,&nbsp;Huancai Lin ,&nbsp;Liangyue Pang","doi":"10.1016/j.identj.2026.109420","DOIUrl":"10.1016/j.identj.2026.109420","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>To develop a multimodal deep learning model for dental caries screening in children by integrating intraoral photographs and questionnaire-based data, and to compare its performance against that of a unimodal model utilising images alone.</div></div><div><h3>Methods</h3><div>In total, 7671 images (3913 occlusal and 3758 smooth surfaces) were collected from children across different dentition stages. Oral health questionnaires were also conducted. The images were clinically labelled into three categories: caries-free, early caries, and moderate-to-severe caries. A multimodal model integrating intraoral images and questionnaire data was trained and evaluated against an image-only unimodal model. The performance metrics included accuracy, precision, recall, F1 score, and the area under the receiver operating characteristic curve (ROC-AUC). SHapley Additive exPlanations (SHAP) analysis was conducted to interpret feature importance.</div></div><div><h3>Results</h3><div>For the multimodal model, occlusal surface classification achieved an accuracy of 92.3% for the caries-free category, 89.2% for the early caries category, and 93.7% for the moderate-to-severe caries category, with ROC-AUCs of 0.967, 0.911, and 0.972, respectively. The performance of smooth surfaces was similarly strong (an accuracy of 92.1% for the caries-free category, 96.7% for the early caries category, and 93.4% for the moderate-to-severe caries category), with ROC-AUCs of 0.938, 0.908, and 0.963, respectively. Incorporating questionnaire data improved recall for the early caries category without compromising overall accuracy. SHAP analysis provided interpretable insights into model decision-making.</div></div><div><h3>Conclusion</h3><div>Compared with the image-only unimodal model, the multimodal deep learning model increased early caries recall while preserving overall diagnostic performance.</div></div><div><h3>Clinical relevance</h3><div>This study describes a multimodal caries intelligent screening model, demonstrating its potential as a population-level screening tool. However, further large-scale, multicentre validation is necessary to confirm its generalisability and effectiveness.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109420"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exopolysaccharides of Streptococcus mutans Enhance Oral Colonisation and Drug Tolerance in Helicobacter pylori","authors":"Yujia Hao ,&nbsp;Yuqiu Huang ,&nbsp;Ruonan Chen ,&nbsp;Yuqing Li ,&nbsp;Xiaojing Huang","doi":"10.1016/j.identj.2026.109405","DOIUrl":"10.1016/j.identj.2026.109405","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>The oral cavity is an extragastric reservoir for <em>Helicobacter pylori</em> (<em>H. pylori</em>), preventing its gastric eradication and causing recurrence. However, the oral environment is not ideal for <em>H. pylori</em>, and the factors facilitating oral <em>H. pylori</em> survival and colonisation are unclear. We explored how exopolysaccharides (EPSs), the fundamental building blocks of <em>Streptococcus mutans</em> (<em>S. mutans</em>) biofilms, affect <em>H. pylori</em> colonisation and drug tolerance in the oral cavity.</div></div><div><h3>Methods</h3><div>The EPS contents of 3 <em>S. mutans</em> biofilms (UA159, UA159Δ<em>gtfB</em>, and UA159Δ<em>gtfBC</em>) were determined via confocal laser scanning microscopy (CLSM). A coculture system of the <em>H. pylori</em> Sydney strain (SS1) and the 3 biofilms was established. The bacterial morphology and adhesive forces of the coculture systems were detected by scanning electron microscopy (SEM) and atomic force microscopy (AFM), respectively. CLSM observations confirmed the ability of glucosyltransferases (Gtfs) from <em>S. mutans</em> to form EPSs around SS1. The tolerance of SS1 to 2 representative antibiotics in the presence of EPSs was confirmed via colony-forming unit (CFU) counting and <em>in vivo</em> experiments.</div></div><div><h3>Results</h3><div>As the EPS content of the <em>S. mutans</em> biofilms increased, both the adhesive forces between SS1 and the <em>S. mutans</em> biofilms and the number of colonised SS1 cells increased. We extracted active Gtfs from UA159 and confirmed that Gtfs synthesised EPSs around SS1. The EPSs gradually accumulated over time, eventually encapsulating SS1. Both <em>in vitro</em> and <em>in vivo</em> experiments confirmed that <em>S. mutans</em> EPSs help protect SS1 against amoxicillin or clarithromycin, potentially confounding gastric lesion outcomes.</div></div><div><h3>Conclusions</h3><div><em>S. mutans</em> biofilms mediate the adhesion, colonisation, and antibiotic tolerance of oral <em>H. pylori</em> via Gtf-driven EPS biosynthesis.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109405"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NLRP12 Alleviated Periodontal Destruction via Suppressing Nuclear Factor Kappa-B Signalling Pathway","authors":"Shuangshuang Xu ,&nbsp;Weiping Wang ,&nbsp;Yuhui Sun,&nbsp;Juefei Wu,&nbsp;Wenting Zhang,&nbsp;Gang Ding","doi":"10.1016/j.identj.2026.109417","DOIUrl":"10.1016/j.identj.2026.109417","url":null,"abstract":"<div><h3>Objective</h3><div>Periodontal ligament stem cells (PDLSCs) have been shown to demonstrate robust tissue regeneration capabilities. NACHT, leucine-rich repeat and PYD-containing 12 (NLRP12) could exerts negative inflammatory regulatory role in various pathological contexts. The effects of NLRP12 on the inflammatory responses and osteogenesis of PDLSCs under inflammatory microenvironment and underlying mechanisms remain unknown.</div></div><div><h3>Methods</h3><div>PDLSCs were isolated, cultured, and characterized, and the expression level of NLRP12 was analysed following lipopolysaccharide (LPS) treatment. Then, <em>NLRP12</em> was overexpressed in PDLSCs via lentivirus transfection. Inflammatory factors were detected by quantitative real-time polymerase chain reaction, osteogenic markers were quantified using quantitative real-time polymerase chain reaction, Western blot, and the capability of osteogenesis was assessed through alkaline phosphatase staining and alizarin red staining. The underlying signalling pathways were examined by Western blot analysis and agonist treatment. Moreover, rat periodontitis models established by ligature method were used to evaluate the regulatory effects of NLRP12 on PDLSC-mediated anti-inflammation and periodontal regeneration <em>in vivo</em>.</div></div><div><h3>Results</h3><div>PDLSCs exhibited mesenchymal stem cell characteristics with multilineage differentiation. NLRP12 was downregulated in LPS-treated PDLSCs. LPS upregulated inflammatory factor expression while downregulating anti-inflammatory factors and suppressing PDLSCs’ osteogenic differentiation, which were reversed by <em>NLRP12</em> overexpression. Mechanistically, nuclear factor kappa-B signalling pathway participated in these processes. Furthermore, microscopic computed tomography scanning, histological analysis, and immunohistochemical staining revealed that NLRP12 ameliorated inflammation and enhanced periodontal regeneration in periodontitis animal models.</div></div><div><h3>Conclusions</h3><div>NLRP12 suppressed inflammatory responses while enhancing osteogenic differentiation of PDLSCs via downregulating the activation of the nuclear factor kappa-B pathway, indicating that NLRP12 is a latent target for enhancing PDLSCs-based periodontal tissue regeneration.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109417"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics, Citation Analysis, and Altmetrics Impact of Retracted Papers in Dentistry (2001-2024)","authors":"Alireza Jafari ,&nbsp;Shohreh SeyyedHosseini ,&nbsp;Reza BasirianJahromi","doi":"10.1016/j.identj.2026.109406","DOIUrl":"10.1016/j.identj.2026.109406","url":null,"abstract":"<div><h3>Background</h3><div>Retraction is a mechanism for correcting published scholarly literature and alerting readers to seriously flawed or erroneous content, or ethical issues, in the literature they are reading. The objectives of this study were to identify the reasons for retraction, analyse citations, and describe the scientific and Altmetrics impacts of retracted papers in dentistry, oral health, and medicine.</div></div><div><h3>Methods</h3><div>The present study was an applied, descriptive-analytical investigation conducted using Scientometric methods and the Altmetrics index. The research population consisted of 231 retracted scientific articles in the subject areas of Dentistry, Oral Surgery, and Medicine, which were indexed in the Web of Science database between 2001 and 2024. Statistical methods, including frequency, mean, and Spearman’s correlation, were employed for data analysis using R software.</div></div><div><h3>Results</h3><div>The findings showed that out of the 231 retracted articles, 156 articles collectively received 2271 citations. Q1 journals have hosted the most retracted articles. Spain has the highest number of retracted articles in the field of dentistry worldwide. Falsification/fabrication of data is the most important reason for the retraction of articles. Mendeley had the highest share of retracted papers in dentistry among the reference management tools. The correlation coefficient between Altmetrics impact and scientific impact was significant (<em>P</em> &lt; .05).</div></div><div><h3>Conclusion</h3><div>As dentistry and oral health are a pivotal field within the biomedical sciences, they exert a substantial influence on the health of the population. For the preceding decades, it has remained imperative for dentistry researchers to dedicate greater attention to all phases of their research process, encompassing the study design, review process, and publication stage.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109406"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographical Variation in Lip Print Patterns Among Adolescents from the High Andean Quechua and Suni Regions in Perú","authors":"Juan Espinoza ,&nbsp;Cesar Mauricio-Vilchez ,&nbsp;Julia Medina ,&nbsp;Fran Espinoza-Carhuancho ,&nbsp;Ivan Calderon ,&nbsp;Arnaldo Munive-Degregori ,&nbsp;Frank Mayta-Tovalino","doi":"10.1016/j.identj.2026.109416","DOIUrl":"10.1016/j.identj.2026.109416","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study was to determine the lip print patterns among adolescents from the Quechua and Suni ecological regions of Ancash, Peru, and to explore the relationship between the variables and their differentiation using logistic regression models.</div></div><div><h3>Methods</h3><div>A quantitative, observational, prospective, cross-sectional, and analytical study was conducted. The sample comprised 192 adolescents from representative educational institutions, who requested the informed consent of their relatives. Personal and anthropometric data were recorded, and lip prints were obtained according to the conventional system of lipstick and adhesive tape using the classifications by Suzuki &amp;Tsuchihashi and Renaud.</div></div><div><h3>Results</h3><div>The population was predominantly male (55.2%) and more represented from the Quechua population (61.5%). Regarding their nutritional status, it was found that more than half were in average nutritional status (53.6%), although a significant proportion was overweight (41.8%). Regarding the Suzuki patterns, there was a predominance of types II (52.1–55.8%) and IV (50.5%), while the Renaud patterns presented a predominance of types G (49% in the upper left quadrant) and E (36.4–38.1%) in the lower quadrants. In the multivariate analysis, it could be identified that the only factor significantly associated with the Suzuki pattern was the geographical region. Adolescents from the Suni region presented this pattern more frequently than those of the Quechua population (60% lower odds, compared with Quechua adolescents: OR = 0.40; 95% CI: 0.22–0.73; p = 0.003). Sex, age, weight and height had no significant associations.</div></div><div><h3>Conclusion</h3><div>The results indicate that lip print patterns have a characteristic dominant pattern in high Andean adolescents, with a significant influence of the geographic region on the morphology of the lips. The results underscore the significance of lip prints as a biometric method and offer proof of the morphological diversity of the Andean populations.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109416"},"PeriodicalIF":3.7,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Self-Medication Behaviour in Response to Dental Pain in Two Populations, France","authors":"Louise Le Texier ,&nbsp;Chantal Savanovitch ,&nbsp;Emmanuel Nicolas ,&nbsp;Pierre-Yves Cousson","doi":"10.1016/j.identj.2026.109418","DOIUrl":"10.1016/j.identj.2026.109418","url":null,"abstract":"<div><h3>Introduction and aims</h3><div>Self-medication appears to be a common practice for dental pain. However, in France, its prevalence and patterns in dentistry have never been studied. The primary objective was to assess the prevalence and self-medication behaviours in two at-risk populations: patients consulting for acute pulpal or periapical pain and patients with dental anxiety requiring treatment under general anaesthesia. The secondary objective was to examine the influence of socio-behavioural factors on these practices.</div></div><div><h3>Method</h3><div>Between April 2021 and May 2023, the behaviours of two at-risk population regarding self-medication were analysed in a cross-sectional observational study. The first population regrouped patients referred to an endodontic postemergency care unit after visiting the emergency service of a dental hospital. These patients were referred due to acute pulpal or periapical pain (Endodontic Group). The second population regrouped patients referred to a special care unit for dental treatment under general anaesthesia due to dental anxiety (Anxiety Group). Self-medication behaviours of the two at-risk populations were analysed with 5 self-administered questionnaires (self-medication, EPICES, IDAF-4C, Pain Catastrophizing Scale, Socio-demographic data). Comparisons between the two population were done using Pearson’s chi-square and Student’s <em>t</em> tests.</div></div><div><h3>Results</h3><div>During the study period, 43 patients were included in the endodontic group and 66 in the anxiety group. Socio-demographic and behavioural data differed between the two groups. However, self-medication prevalence was similar (51.2% in the Endodontic Group <em>vs</em> 45.5% in the Anxiety Group), as were self-medication behaviours (types and number of substances used, methods of acquisition, knowledge). No socio-demographic or behavioural factors explained these attitudes.</div></div><div><h3>Conclusion</h3><div>Self-medication in dentistry is often overlooked or poorly managed. Preventive measures and patient education on the proper use of medication are essential.</div></div><div><h3>Clinical relevance</h3><div>Standardized cooperation protocols should be developed involving dentists and community pharmacists to optimize the management of patients suffering from dental pain.</div></div>","PeriodicalId":13785,"journal":{"name":"International dental journal","volume":"76 2","pages":"Article 109418"},"PeriodicalIF":3.7,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}