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Using Storytelling Robot for Supporting Autistic Children in Theory of Mind 用讲故事机器人支持自闭症儿童的心智理论
Pub Date : 2019-01-01 DOI: 10.17706/IJBBB.2019.9.2.100-108
Sujirat Attawibulkul, Natthanicha Sornsuwonrangsee, Wisanu Jutharee, B. Kaewkamnerdpong
Autistic children have deficit in the understanding of how other people think and feel which is an important factor for social interaction and social communication. The understanding of how other people think and feel is called theory of mind. The storytelling activity could help the autistic children to learn about the theory of mind from the communication between the characters in the story stand point. This study investigated the use of BLISS robot with mobile application in the storytelling activity for supporting the theory of mind in autistic children. Five children between 4 and 12 years old were recruited. All children listened to the story and answered questions about theory of mind from their parents in first week. For second week, all children listened to the story and answered question from BLISS robot that was controlled by their parents. Experimental result suggested that all children stay engaged throughout the storytelling activity. It was shown that BLISS robot can be used to reduce the burden of parent in storytelling activity. Moreover, some autistic children can answer all questions about theory of mind correctly.
自闭症儿童在理解他人的想法和感受方面存在缺陷,这是社会互动和社会沟通的重要因素。对他人如何思考和感受的理解被称为心理理论。讲故事活动可以帮助自闭症儿童从故事中人物的交流中学习心理理论。本研究探讨了移动应用BLISS机器人在自闭症儿童讲故事活动中对心智理论的支持。招募了5名4至12岁的儿童。在第一周,所有的孩子都听了这个故事,并回答了父母关于心理理论的问题。第二周,所有孩子听故事并回答由父母控制的BLISS机器人的问题。实验结果表明,所有儿童在整个讲故事活动中都保持专注。结果表明,BLISS机器人可以减轻家长讲故事活动的负担。此外,一些自闭症儿童可以正确回答所有关于心理理论的问题。
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引用次数: 8
BreastNet: Entropy-Regularized Transferable Multi-task Learning for Classification with Limited Breast Data 乳房网:用有限乳房数据进行分类的熵正则化可转移多任务学习
Pub Date : 2019-01-01 DOI: 10.17706/IJBBB.2019.9.1.20-26
Jialin Shi, Ji Wu, Ping Lv, Jiajia Guo
We describe a framework to automatically separate malignant from benign breast lesions using limited breast ultrasound data. The main uniqueness of this framework includes: (1) in terms of the unique shape features of breast lesions, two types of image patches are designed to fine-tune pre-trained models, aiming to characterize the overall appearance and heterogeneity in shapes of breast lesions. (2) taking the BI-RADS regression task as an auxiliary task, a multi-task architecture is proposed to improve the accuracy of classification. (3) instead of prevalent cross-entropy loss, we introduce training with confusion by means of regularizing prediction entropy to prevent overfitting. Extensive experimental results on small-scale breast ultrasound dataset corroborate that the proposed framework is superior to the state-of-the-art approaches in breast lesions classification with limited data. Besides, we provide detailed analysis of the choice of regularizing parameter and visual evidence that introduction of confusion leads to increase in feature generalization.
我们描述了一个框架,自动区分恶性和良性乳腺病变使用有限的乳房超声数据。该框架的主要独特性包括:(1)针对乳腺病变独特的形状特征,设计了两种类型的图像补丁来微调预训练模型,旨在表征乳腺病变的整体外观和形状的异质性。(2)以BI-RADS回归任务为辅助任务,提出多任务架构,提高分类准确率。(3)代替普遍存在的交叉熵损失,采用正则化预测熵的方法引入带混淆的训练,防止过拟合。在小规模乳腺超声数据集上的大量实验结果证实,该框架在数据有限的情况下优于最先进的乳腺病变分类方法。此外,我们对正则化参数的选择进行了详细的分析,并给出了引入混淆导致特征泛化提高的视觉证据。
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引用次数: 5
Comparative Study on Does Energy Drink Effect on the Reaction Time? 功能饮料对反应时间影响的比较研究
Pub Date : 2019-01-01 DOI: 10.17706/IJBBB.2019.9.1.59-64
Mashal Fatima, Aimen Malik, Seerat Fatima, M. Shafique
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引用次数: 0
Lipid-Lowering Property of Flavonoid-Rich Portion of Combretum Micranthumon High Fat Diet Induced Hyperlipidemic Rats 高脂血症大鼠高脂饮食中富黄酮部分的降脂作用
Pub Date : 2019-01-01 DOI: 10.17706/IJBBB.2019.9.1.42-50
A. Babandi, N. Musa, M. Ya’u, H. Yakasai, D. Shehu, K. Babagana, A. Ibrahim
The lipid-lowering potential of flavonoid-rich portion of Combretum micranthum (CM) on a high-fat diet (HFD) induced albino rats was evaluated. Hyperlipidaemic rats were divided into six groups. Group I (Normal control), group II (HFD-fed only), while group III, IV and V received aqueous methanol (80%) leaf extract of CM at varied doses of 100, 200 and 400 mg/kg, respectively, while group VI were given the standard drugAtorvastatin (4 mg/kg) for two weeks. Total Cholesterol (TC), Triacylglycerol (TAG), High Density Lipoproteins (HDL-C), Creatine Kinase (CK), and Lactate Dehydrogenase (LDH) were assayed spectrophotometrically and Atherogenic Index (AI) calculated using standard formula. GC-MS revealed 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one, 5-oxycatechol and 1,2,3benzenetriol to be the principal compounds. Significant reduction in TC, TAG, LDL-C, AI, CK, LDH and increased in HDL-C were observed compared to hyperlipidemic control (p<0.05) hence CM could be used in the management of risk of CVDs.
研究了高脂饮食诱导的白化病大鼠的降脂作用。将高脂血症大鼠分为6组。I组(正常对照)、II组(仅饲喂hfd), III、IV、V组分别给予100、200、400 mg/kg不同剂量的紫荆叶提取物水溶液(80%),VI组给予标准药物阿托伐他汀(4 mg/kg),疗程2周。分光光度法测定总胆固醇(TC)、三酰甘油(TAG)、高密度脂蛋白(HDL-C)、肌酸激酶(CK)、乳酸脱氢酶(LDH),并用标准公式计算致动脉粥样硬化指数(AI)。GC-MS显示2,3-二氢-3,5-二羟基-6-甲基- 4h -吡喃-4- 1,5 -氧儿茶酚和1,2,3苯三醇是主要化合物。与高脂血症对照组相比,TC、TAG、LDL-C、AI、CK、LDH均显著降低,HDL-C升高(p<0.05), CM可用于心血管疾病的风险管理。
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引用次数: 2
Anthelmintic Potential of Tamarind (Tamarindus indica) Seeds 罗望子种子的驱虫潜力
Pub Date : 2019-01-01 DOI: 10.17706/ijbbb.2019.9.3.194-201
Andrea Nicolas, Liwayway H. Acero
Ascaris suum is known to be the prevalent internal parasites affecting swine. Swine raisers are beset with poor average daily gain in weight of swine, once this parasite competes with the nutritional requirement of the animal. The seeds of Tamarindus indica are commonly thrown after consumption of the fruit pericarp, without realizing its potential anthelmintic use. This study determined the mortality of A. suum exposure to different concentrations of Tamarind seed extract at 36 hours observation. Experimental research method with 4 treatments and 10 samples per treatment was used to gather pertinent data in this study. Thad 10 A. suum exopose to Goodwins solution, T+ had 10 A. suum exposure to Goodwins and Albendazole, T1 had 10 A. suum, Goodwins solution and 40% Tamarind seed extract (TSE) and T2 had 10 A. suum, Goodwins solution and 80% TSE. Data were analyzed by Analysis of Variance and Fisher Least Significant Difference test was employed to determine what treatment is significant over the other.. Result of the study revealed that T2 (80% TSE) killed the A. suum as early as 12 hours of exposure while A. suum in T1 (40% TSE) had 90% mortality at 24 hours of exposure. This implies that TSE is potent at 12 hours of exposure at 80% concentration and can be used as anthelmintics from herbal source.
猪蛔虫是一种常见的猪体内寄生虫。一旦这种寄生虫与动物的营养需求竞争,养猪户就会受到猪平均日增重差的困扰。柽柳的种子通常在食用果皮后被扔掉,而没有意识到它潜在的驱虫作用。本研究测定了不同浓度罗望子提取物暴露于南角田鼠36小时的死亡率。本研究采用4个处理,每个处理10个样本的实验研究方法来收集相关数据。T+组暴露于固胜液10次,T+组暴露于固胜液和阿苯达唑10次,T1组暴露于固胜液和40%罗望子提取物(TSE) 10次,T2组暴露于固胜液和80% TSE。采用方差分析方法对数据进行分析,并采用Fisher最小显著性差异检验来确定哪种治疗比其他治疗显著。结果表明,T2(80%的TSE)暴露在12小时内就杀死了水蛭,而T1(40%的TSE)暴露在24小时内的水蛭死亡率为90%。这意味着TSE在80%浓度下暴露12小时时是有效的,并且可以用作草药来源的驱虫剂。
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引用次数: 2
Comparison of EPS Extraction Efficiences from Spirogyra fluviatilis by Chemical and Physical Extraction Methods 化学和物理提取法提取水绵中EPS的效果比较
Pub Date : 2019-01-01 DOI: 10.17706/ijbbb.2019.9.4.202-209
Shuiping Chang, Hwey-Lin Sheu, Yi-Chao Lee
The algal extracellular polymeric sustances (EPS) have been studied as natural resources for a number of applications. For a macroalgae Spirogyra fluviatilis, the aboundant extracellular matrix on the surface of algae cell. EPS has a gel-like structure that could fractioned into loosely bound EPS (LB-EPS) and tightly bound EPS (TB-EPS). The contents and extraction rate of EPS were compared two chemical (formaldehyde-NaOH and NH4OH) and two physical (ultrasonication and heating) extraction methods. The analysis demonstrated that extraction rates of EPS followed heating (7.94 mg g-1 fresh algae) > ultrasonication (5.02 mg g-1 fresh algae) > formaldehyde-NaOH (3.12 mg g-1 fresh algae) > NH4OH (2.01 mg g-1 fresh algae). The protein to polysaccharides ratio (P/S) in EPS is between 0.23 to 0.35 by chemical methods and between 0.27 to 0.37 by physical methods. The P/S ratio is LB-EPS is higher than TB-EPS. The results indicated that the EPS could be efficiently extracted by the heating method, the influence of P/S ratios were obvious different.
藻类细胞外聚合物(EPS)作为一种天然资源被广泛应用。对于一种大型藻,水绵藻细胞表面丰富的细胞外基质。EPS具有凝胶状结构,可分为松散结合的EPS (LB-EPS)和紧密结合的EPS (TB-EPS)。比较了两种化学方法(甲醛- naoh和NH4OH)和两种物理方法(超声波和加热)提取EPS的含量和提取率。分析表明,EPS的提取率依次为加热(7.94 mg g-1鲜藻)、超声波(5.02 mg g-1鲜藻)、甲醛-氢氧化钠(3.12 mg g-1鲜藻)、氨水(2.01 mg g-1鲜藻)。化学法测定EPS的蛋白多糖比为0.23 ~ 0.35,物理法测定EPS的蛋白多糖比为0.27 ~ 0.37。市盈率为LB-EPS高于TB-EPS。结果表明:采用加热法提取EPS是有效的,但P/S比的影响有明显差异。
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引用次数: 5
Investigation of Antioxidant Properties on Some Garlic Varieties and Influence of Farming Inputs on the Quality of Garlic 部分大蒜品种抗氧化性能及农作投入对大蒜品质影响的研究
Pub Date : 2019-01-01 DOI: 10.17706/ijbbb.2019.9.3.180-187
U. Fitrotin, B. N. Hidayah
The antioxidant activities of garlic are influenced by its variety and farming practices. The objectives of this research were to determine the phenolic compounds and antioxidant activities of garlic varieties which were marketed in Indonesia. The phenolic compounds were determined with Folin-Ciocalteu and antioxidant activities were examined using 2,2-diphenyl-2-phicrylhydrazyl (DPPH). Ascorbic acid was used as antioxidant reference. In this experiment, nine garlic varieties from different region in the world, as well as in Indonesia were investigated. Those varieties were Chinese, Egyptian, Indian, Sangga Sembalun (purple), Sangga Sembalun (white), Sangga Nunggal, Lumbu Kuning, Lumbu Hijau, and Ncuna Sambori. The results showed that antioxidant activities of Lumbu Hijau, Sangga Sembalun (white) and Ncuna Sambori were among the highest but not different statistically (p<0.05). Moreover, Sangga Sembalun (purple), Lumbu Kuning, Indian, Sangga Nunggal and ascorbic acid 15 ppm (as comparison) were in the second level and not different statistically (p<0.05), while Chinese and Egyptian varieties were the lowest. Sangga Sembalun (white) variety was further cultivated with different dose of farming inputs (manure, dolomite, NPK, SP-36, ZA, Urea and KCl). Results showed that the antioxidant activities of Sangga Sembalun (white) which was cultivated with different dose of farming inputs were not different statistically (p<0.05). In general, different dose of farming inputs in farming practices were not changed the antioxidant activities of garlic variety.
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引用次数: 4
Analysis of Impact Force on Runner’s Foot during Stance Phase 跑动者站立阶段足部冲击力分析
Pub Date : 2019-01-01 DOI: 10.17706/ijbbb.2019.9.1.51-58
F. Flaviana, R. Suryantari
The aim of this research is to analyze the effect of two types of running shoes on runner’s foot during stance phase, using two force plates equipped with specified track board. The main method that will be discussed in this paper is system design of gait analysis with the specific setting, in order to acquire ground reaction force (GRF) data. Then we use that experimental data to calculate the impulse during stance phase using Trapezoidal rule. The benefit of this study is to provide information and new ideas about running and its prevention over an injury. When observed from the bar chart of the maximum GRF normalized to body weight value of the four subjects using each of the R, M, and B shoe soles, it seems that when the four subjects used footwear with R (Reg) sole shoe, the subject experienced the maximum force (i.e. 2.9 by the 3rd subject) compared when using shoe sole M (Run), or barefoot B (Bare). Whereas when the subject does not use footwear (B), they did not experience a significant difference when compared with the subject of wearing footwear with shoe sole M. That also means when the 3rd subject stands still above the force plate, it generated the force output of the gravity or the weight of the subject (the average body weight of 3rd subject is 529.2 N). The ratio of the force gain experienced by the foot of the 3rd subject during the stance phase can reach up to 2.9 times compared to when she stood still. Total impulse that were experienced by the 4th subject during stance phase are the summation of those two integrals (199.22 N.s and 190.52 N.s). The measurement of foot impulse on stance phase using Trapezoidal Rule is the approximation by integrating the area under the curve in the form of polynomial function. From the impulse data that were obtained, that have not the clear correlation between sole shoes were worn with the foot impulse on stance phase.
本研究的目的是分析两种类型的跑鞋在站立阶段对跑步者足部的影响,使用两个配有指定轨迹板的力板。本文主要讨论的方法是基于特定设定的步态分析系统设计,以获取地面反作用力数据。然后利用该实验数据,利用梯形法则计算姿态阶段的脉冲。这项研究的好处是提供了关于跑步及其预防伤害的信息和新想法。从使用R、M和B鞋底的四名受试者的最大GRF与体重值归一化的柱状图中观察,当四名受试者使用R (Reg)鞋底的鞋子时,与使用M (Run)鞋底或赤脚B (Bare)鞋底时相比,第三名受试者所承受的最大力为2.9。而当被试不穿鞋(B)时,他们与穿鞋底为m的鞋的被试相比没有显著差异。这也意味着当第三个被试静止站在测力板上方时,它产生了重力或被试体重的力输出(第三个被试的平均体重为529.2 N)。第三个被试的脚在站立阶段所承受的力与静止时的比可达2.9倍。第4个被试在站立阶段所经历的总脉冲是这两个积分(199.22 N.s和190.52 N.s)的和。用梯形法则测量脚脉冲在姿态相位上的测量是将曲线下面积以多项式函数的形式积分的近似。从所获得的脉冲数据来看,所穿鞋底与站立阶段足部脉冲之间没有明显的相关性。
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引用次数: 0
Process Mining in Cardiology: A Literature Review 心脏病学过程挖掘:文献综述
Pub Date : 2018-10-01 DOI: 10.17706/IJBBB.2018.8.4.226-236
G. Kusuma, M. Hall, C. Gale, O. Johnson
Process mining is a data analytics approach which has shown promising results in healthcare including the potential to improve the management of chronic diseases such as cardiovascular disease (CVD). CVD are one of the leading causes of premature death worldwide. Helping healthcare professionals develop a better understanding of how to improve CVD care pathways may result in better outcomes for patients. This paper describes the opportunities for process mining to support such improvements and provides a summary of process mining studies undertaken in the field of cardiology. The initial search found 1,597 potentially relevant papers which, after a systematic review, identified a final set of 32 relevant studies. These studies were analyzed across five themes: process and data types; research questions; techniques, perspective and tools; methodologies; limitations and suggested future work.
过程挖掘是一种数据分析方法,在医疗保健领域显示出有希望的结果,包括改善心血管疾病(CVD)等慢性疾病管理的潜力。心血管疾病是全世界过早死亡的主要原因之一。帮助医疗保健专业人员更好地了解如何改善心血管疾病护理途径可能会为患者带来更好的结果。本文描述了过程挖掘支持这种改进的机会,并提供了在心脏病学领域进行的过程挖掘研究的总结。最初的搜索发现了1597篇可能相关的论文,经过系统的审查,最终确定了32篇相关的研究。这些研究在五个主题上进行了分析:过程和数据类型;研究问题;技术、观点和工具;方法;局限性和建议的未来工作。
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引用次数: 17
Linear and Nonlinear Analysis of Gait Motor Signal to Diagnose Parkinson’s Disease 步态运动信号的线性和非线性分析诊断帕金森病
Pub Date : 2018-01-01 DOI: 10.17706/IJBBB.2018.8.4.202-209
M. K. Moridani, N. Shahrestani
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引用次数: 0
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International Journal of Bioscience, Biochemistry and Bioinformatics
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