Pub Date : 2023-07-01DOI: 10.22271/27069567.2023.v5.i3a.497
Gehad Abd Alalim Ali Goma, M. Hantera, Ghada Abd Almomen Soliman, S. Hammoudah
{"title":"Procalcitonin levels in COVID-19 patients recruited from Tanta University Hospitals","authors":"Gehad Abd Alalim Ali Goma, M. Hantera, Ghada Abd Almomen Soliman, S. Hammoudah","doi":"10.22271/27069567.2023.v5.i3a.497","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3a.497","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"360 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76753845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.22271/27069567.2023.v5.i3a.501
Hanan M Elgushi, Amr M Gawaly, Heba A Mourad, Waleed S Mohamed
{"title":"Trefoil factor 3, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio as predictor markers in ulcerative colitis activity","authors":"Hanan M Elgushi, Amr M Gawaly, Heba A Mourad, Waleed S Mohamed","doi":"10.22271/27069567.2023.v5.i3a.501","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3a.501","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77257793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.22271/27069567.2023.v5.i3a.499
Mai Elsaid Kiwan, Mervat Ismaeil Hussein, E. Kassem, Amira Yousf Ahmed, D. Alashkar
{"title":"Neutrophil extracellular traps and common carotid intema media thickness as predictors of cardio vascular risk in patients with systemic lupus erythematous","authors":"Mai Elsaid Kiwan, Mervat Ismaeil Hussein, E. Kassem, Amira Yousf Ahmed, D. Alashkar","doi":"10.22271/27069567.2023.v5.i3a.499","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3a.499","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87681314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.22271/27069567.2023.v5.i3a.495
Aya Abd El Hamied El Shintenawy, Sara El Sharkawy, G. Taher, Hanan M. Elsaadany, Mervat Ismaeil Hussein
{"title":"Metabolic syndrome and its risk factors in Rheumatoid arthritis","authors":"Aya Abd El Hamied El Shintenawy, Sara El Sharkawy, G. Taher, Hanan M. Elsaadany, Mervat Ismaeil Hussein","doi":"10.22271/27069567.2023.v5.i3a.495","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3a.495","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"998 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77144092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.22271/27069567.2023.v5.i3a.494
Basma Ali Elsaadany, E. Elhawary, K. M. Ayad, M. Alshishtawy
{"title":"Effect of continued support and mother's counseling on the duration of exclusive breastfeeding in a rural area in Egypt","authors":"Basma Ali Elsaadany, E. Elhawary, K. M. Ayad, M. Alshishtawy","doi":"10.22271/27069567.2023.v5.i3a.494","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3a.494","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"13 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72615039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.22271/27069567.2023.v5.i3a.492
Sara Adel Elsendiony, Muhammad Tarek Abdel Ghafar, M. Sweilam, Nesreen Ahmad Kotb, Morad Ahmad Morad
Background: One of the most prevalent and serious side effects of diabetes mellitus (DM) is diabetic nephropathy (DN), which is linked to higher mortality and morbidity rates in diabetic individuals. Autophagy is essential for the survival of podocytes. This work was designed to assess autophagy in individuals with type 2 diabetes mellitus (T2DM) with and without diabetic nephropathy (DN). Methods: This case-control work was performed on 50 patients with T2DM. They were divided according to urinary albumin creatinine ratio (UACR) into the following subgroups; Group IA: 25 individuals without DN and Group IB: 25 individuals with DN. Every individual who participated had a medical taking of history and laboratory tests including routine investigations of Fasting blood sugar (FBS), HbA1c, Urinary albumin creatinine ratio (UACR), Estimated Glomerular Filtration Rate (eGFR) and C-reactive protein (CRP) and specific Detection of LAMP2 relative gene expressions in peripheral leucocytes by quantitative reverse transcription-real time PCR (qRT-qPCR). Results: LAMP2 mRNA expression levels were substantially decreased in diabetic individuals with nephropathy than in those without. Conclusions: These data suggest that there was inhibition of the autophagy pathway in diabetic individuals with DN than in those without and that impaired autophagy may be involved in the progression to DN.
{"title":"Study of some autophagy markers in type 2 diabetic patients with and without diabetic nephropathy","authors":"Sara Adel Elsendiony, Muhammad Tarek Abdel Ghafar, M. Sweilam, Nesreen Ahmad Kotb, Morad Ahmad Morad","doi":"10.22271/27069567.2023.v5.i3a.492","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3a.492","url":null,"abstract":"Background: One of the most prevalent and serious side effects of diabetes mellitus (DM) is diabetic nephropathy (DN), which is linked to higher mortality and morbidity rates in diabetic individuals. Autophagy is essential for the survival of podocytes. This work was designed to assess autophagy in individuals with type 2 diabetes mellitus (T2DM) with and without diabetic nephropathy (DN). Methods: This case-control work was performed on 50 patients with T2DM. They were divided according to urinary albumin creatinine ratio (UACR) into the following subgroups; Group IA: 25 individuals without DN and Group IB: 25 individuals with DN. Every individual who participated had a medical taking of history and laboratory tests including routine investigations of Fasting blood sugar (FBS), HbA1c, Urinary albumin creatinine ratio (UACR), Estimated Glomerular Filtration Rate (eGFR) and C-reactive protein (CRP) and specific Detection of LAMP2 relative gene expressions in peripheral leucocytes by quantitative reverse transcription-real time PCR (qRT-qPCR). Results: LAMP2 mRNA expression levels were substantially decreased in diabetic individuals with nephropathy than in those without. Conclusions: These data suggest that there was inhibition of the autophagy pathway in diabetic individuals with DN than in those without and that impaired autophagy may be involved in the progression to DN.","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73962376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.22271/27069567.2023.v5.i3b.503
Asmaa Mohamed Kandeel, Eman Ali Younis, Gamalat Mohamed Ali, I. Kabbash
{"title":"Corona virus (COVID-19) infection: Perception based practices and obstacles of prevention among mothers in a rural area","authors":"Asmaa Mohamed Kandeel, Eman Ali Younis, Gamalat Mohamed Ali, I. Kabbash","doi":"10.22271/27069567.2023.v5.i3b.503","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3b.503","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76683289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.22271/27069567.2023.v5.i3b.513
Hasen A Alghamdi, Abdullah M Alghamdi, M. A. Alasmari, Abdullah S Mahdi, Hofan M Algarni, Abdulrahman S Almalki, Khalid S Alqurashi, Abdullah A Alzahrani, Naif S Alghamdi, Sultan F Abualhmayl, Emad A Alghamdi, Anas A Aljehani, Sami A Alghamdi, Muteb F Alotaibi
{"title":"Comprehensive review of lab findings and imaging evaluation of non-alcoholic fatty liver disease NAFLD in elderly patients","authors":"Hasen A Alghamdi, Abdullah M Alghamdi, M. A. Alasmari, Abdullah S Mahdi, Hofan M Algarni, Abdulrahman S Almalki, Khalid S Alqurashi, Abdullah A Alzahrani, Naif S Alghamdi, Sultan F Abualhmayl, Emad A Alghamdi, Anas A Aljehani, Sami A Alghamdi, Muteb F Alotaibi","doi":"10.22271/27069567.2023.v5.i3b.513","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3b.513","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139371447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.22271/27069567.2023.v5.i3b.514
Dr. Srinidhi Kondepudi
{"title":"Case report of myocardial infarction in a septuagenarian with Situs Inversus Totalis","authors":"Dr. Srinidhi Kondepudi","doi":"10.22271/27069567.2023.v5.i3b.514","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3b.514","url":null,"abstract":"","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139371913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.22271/27069567.2023.v5.i3b.505
Hend Ali El-Feky, Mohamed Enaba, Mohamed Khalfallah, Mohamed Abdelmotaal Safa
Background: NAFLD is the commonest liver pathology globally which is distinguished by hepatic steatosis without evidence of secondary injurious hepatic agents.The spectrum of liver affection in NAFLD is variable starting from mild steatosis to evident fibrosis and may extend to extra hepatic morbidities.CVD is one of the highly serious systemic comorbidities of NAFLD including various degrees of cardiovascular dysfunction especially at the level of left ventricle.Whole blood viscosity (WBV) is an important rheological parameter that affects blood flow in the circulation with subsequent affection of tissue perfusion, so investigators try to elucidate the role of WBV as a crucial player in the etiopathogenesis of LVD in NAFLD cases and hence its use as an early preditictor marker.Patients and Methods: This is a cross sectional study that was carried out on 50 NAFLD cases grouped into 2 groups based on the existence presence of LVD: Group 1 included 26 patients with LVD, group 2 included 24 patients without LVD. The patients’ demographic, clinical, laboratory and radiological data were recorded on a special observation sheet. Whole blood viscosity and ECHO cardiography assessment of the left ventricular function of patients were also recorded. Statistical analysis was done for all collected data using the IBM, SPSS version 23. Significance of obtained results was considered at p-value of less than 0.05.Results: WBV was significantly increased in group 1 compared to group 2. WBV had appeared to be an excellent predictor of LVD in patients with NAFLD; it was positively correlated with hemoglobin, hematocrit, fatty liver status and fibrosis and all LVD parameters except for ejection fraction and relative wall thickness. By logistic regression analysis hemoglobin, whole blood viscosity, and left ventricular end-diastolic diameter are the only predictors in NAFLD patients with LVD. WBV at a cut-off value of 4.38; the AUC was 0.756, the sensitivity was 96.15%, the specificity was 83.33%, the PPV was 86.20%, and the NPV was 95.23%.Conclusion: WBV is a good, easily obtained and affordable marker for the determination of LVD in cases with NAFLD.
背景:NAFLD是全球最常见的肝脏病理，以肝脂肪变性为特征，无继发性肝损伤因子的证据。NAFLD对肝脏的影响范围是可变的，从轻微的脂肪变性到明显的纤维化，并可能扩展到肝外病变。CVD是NAFLD高度严重的全身合并症之一，包括不同程度的心血管功能障碍，特别是在左心室水平。全血粘度(WBV)是一个重要的流变参数，它影响循环中的血液流动，进而影响组织灌注，因此研究人员试图阐明WBV在NAFLD中LVD发病机制中的重要作用，并因此将其作为早期预测指标。患者和方法:这是一项横断面研究，对50例NAFLD患者进行研究，根据是否存在LVD分为两组:1组26例有LVD患者，2组24例无LVD患者。患者的人口学、临床、实验室和放射学数据记录在一张特殊的观察表上。记录全血黏度及超声心动图左心室功能评价。使用IBM SPSS version 23对收集到的数据进行统计分析。p值小于0.05时，认为所得结果具有显著性。结果:1组WBV明显高于2组。WBV似乎是NAFLD患者LVD的一个很好的预测指标;与血红蛋白、红细胞压积、脂肪肝状态、纤维化及除射血分数和相对壁厚外的所有LVD参数呈正相关。通过logistic回归分析，血红蛋白、全血黏度和左心室舒张末期内径是NAFLD合并LVD患者的唯一预测因子。WBV的临界值为4.38;AUC为0.756，敏感性为96.15%，特异性为83.33%，PPV为86.20%，NPV为95.23%。结论:WBV是检测NAFLD患者LVD的一种简便易行、价格合理的指标。
{"title":"Whole blood viscosity as a predictor of left ventricular dysfunction in patients with Non-Alcoholic Fatty Liver Disease (NAFLD)","authors":"Hend Ali El-Feky, Mohamed Enaba, Mohamed Khalfallah, Mohamed Abdelmotaal Safa","doi":"10.22271/27069567.2023.v5.i3b.505","DOIUrl":"https://doi.org/10.22271/27069567.2023.v5.i3b.505","url":null,"abstract":"Background: NAFLD is the commonest liver pathology globally which is distinguished by hepatic steatosis without evidence of secondary injurious hepatic agents.The spectrum of liver affection in NAFLD is variable starting from mild steatosis to evident fibrosis and may extend to extra hepatic morbidities.CVD is one of the highly serious systemic comorbidities of NAFLD including various degrees of cardiovascular dysfunction especially at the level of left ventricle.Whole blood viscosity (WBV) is an important rheological parameter that affects blood flow in the circulation with subsequent affection of tissue perfusion, so investigators try to elucidate the role of WBV as a crucial player in the etiopathogenesis of LVD in NAFLD cases and hence its use as an early preditictor marker.Patients and Methods: This is a cross sectional study that was carried out on 50 NAFLD cases grouped into 2 groups based on the existence presence of LVD: Group 1 included 26 patients with LVD, group 2 included 24 patients without LVD. The patients’ demographic, clinical, laboratory and radiological data were recorded on a special observation sheet. Whole blood viscosity and ECHO cardiography assessment of the left ventricular function of patients were also recorded. Statistical analysis was done for all collected data using the IBM, SPSS version 23. Significance of obtained results was considered at p-value of less than 0.05.Results: WBV was significantly increased in group 1 compared to group 2. WBV had appeared to be an excellent predictor of LVD in patients with NAFLD; it was positively correlated with hemoglobin, hematocrit, fatty liver status and fibrosis and all LVD parameters except for ejection fraction and relative wall thickness. By logistic regression analysis hemoglobin, whole blood viscosity, and left ventricular end-diastolic diameter are the only predictors in NAFLD patients with LVD. WBV at a cut-off value of 4.38; the AUC was 0.756, the sensitivity was 96.15%, the specificity was 83.33%, the PPV was 86.20%, and the NPV was 95.23%.Conclusion: WBV is a good, easily obtained and affordable marker for the determination of LVD in cases with NAFLD.","PeriodicalId":13835,"journal":{"name":"International Journal of Advanced Research in Medicine","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135144207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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