Objective: Acne is a prevalent skin condition affecting a wide range of age groups, often leading to severe scarring if left untreated. The use of subcision combined with fractional CO2 laser therapy has been posited as a potentially more effective treatment method for atrophic acne scars compared to standalone laser treatment. Methods: This clinical trial was conducted at Asha Derma Clinic, Gorakhpur, Uttar Pradesh, from 30th March 2023 to 30th March 2024. Thirty patients with ice pick and rolling-type atrophic acne scars were enrolled. Participants were treated on one side of their face with five sessions of fractional CO2 laser and on the other side with one session of subcision with fractional CO2 laser combined with four sessions of fractional CO2 laser alone. Outcomes were assessed through scar improvement and patient satisfaction at 1, 2, and 6 mo post-treatment, with data analysis performed using ANOVA and the Wilcoxon rank-sum test. Results: Significant improvements were observed in both recovery levels and patient satisfaction. The combined method showed higher recovery percentages (40-65%, Mean±SD: 54.7±7) compared to the laser alone (30-55%, Mean±SD: 43±11.1), with a p-value of 0.0005. Patient satisfaction also favored the combined method (1.8-3, Mean±SD: 6.6±1.2) over laser treatment alone (1.6-4, Mean±SD: 5.2±1.8), with a p-value of 0.0007. Conclusion: The study demonstrated that subcision combined with fractional CO2 laser therapy significantly enhances recovery levels and patient satisfaction in the treatment of atrophic acne scars, suggesting a robust advantage of integrating both treatments.
{"title":"THE USE OF SUBCISION IN CONJUNCTION WITH FRACTIONAL CARBON DIOXIDE LASER TO IMPROVE ATROPHIC ACNE SCARS","authors":"Priyanka Sharma, Ajit Singh, Aditya Kumar Tripathi","doi":"10.22159/ijcpr.2024v16i4.5019","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5019","url":null,"abstract":"Objective: Acne is a prevalent skin condition affecting a wide range of age groups, often leading to severe scarring if left untreated. The use of subcision combined with fractional CO2 laser therapy has been posited as a potentially more effective treatment method for atrophic acne scars compared to standalone laser treatment.\u0000Methods: This clinical trial was conducted at Asha Derma Clinic, Gorakhpur, Uttar Pradesh, from 30th March 2023 to 30th March 2024. Thirty patients with ice pick and rolling-type atrophic acne scars were enrolled. Participants were treated on one side of their face with five sessions of fractional CO2 laser and on the other side with one session of subcision with fractional CO2 laser combined with four sessions of fractional CO2 laser alone. Outcomes were assessed through scar improvement and patient satisfaction at 1, 2, and 6 mo post-treatment, with data analysis performed using ANOVA and the Wilcoxon rank-sum test.\u0000Results: Significant improvements were observed in both recovery levels and patient satisfaction. The combined method showed higher recovery percentages (40-65%, Mean±SD: 54.7±7) compared to the laser alone (30-55%, Mean±SD: 43±11.1), with a p-value of 0.0005. Patient satisfaction also favored the combined method (1.8-3, Mean±SD: 6.6±1.2) over laser treatment alone (1.6-4, Mean±SD: 5.2±1.8), with a p-value of 0.0007.\u0000Conclusion: The study demonstrated that subcision combined with fractional CO2 laser therapy significantly enhances recovery levels and patient satisfaction in the treatment of atrophic acne scars, suggesting a robust advantage of integrating both treatments.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.5045
D. Pitale, S. N. Jadhav
Objective: The organisation of the human society has undergone a unique transition throughout the last decades. With the rise of ever growing technologization and disruptive innovations, populations also demand more social and environmental initiatives from firms and governments. In 2015, the United Nations (UN) member states agreed upon a 2030 Agenda for Sustainable Development. Developing a sustainable UHC is decisive to ensure better economic prospects and social equality across socioeconomic classes. This can be achieved by lowering the barriers to access health services to the most vulnerable groups and improve mortality and disability rates in the potential workforce. Methods: The present study was conducted in a remote location defence hospital catering to the health care needs of serving personnel of Indian armed forces and civilians residing in this peripheral area. The basic specialties including Obstetrics, paediatrics, medicine and general surgery are provided at this centre 24*7 by the dedicated medical officers of Indian Armed forces. Results: Sustainability of care continuously evolves towards becoming a major factor for public healthcare organisations, and more accountability will likely be demanded of managers to deliver on each aspect of its triple bottom line. This study shows that prevention and patient empowerment both carry great potential to attain this objective. Conclusion: It is necessary to set priorities and act according to available resources and organisational vision. The central threats to sustainability of public health care welfare systems in peripheral hospitals identified, namely the ageing population and rise in chronic diseases. UHC at a meso and micro level, could provide a much better rationale for scholars to evaluate the need for change, and contribute to draft more inclusive sustainable strategies.
{"title":"HOSPITAL ADMINISTRATION IN A PERIPHERAL REMOTE LOCATION HOSPITAL: A EVIDENCE BASED STUDY","authors":"D. Pitale, S. N. Jadhav","doi":"10.22159/ijcpr.2024v16i4.5045","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5045","url":null,"abstract":"Objective: The organisation of the human society has undergone a unique transition throughout the last decades. With the rise of ever growing technologization and disruptive innovations, populations also demand more social and environmental initiatives from firms and governments. In 2015, the United Nations (UN) member states agreed upon a 2030 Agenda for Sustainable Development. Developing a sustainable UHC is decisive to ensure better economic prospects and social equality across socioeconomic classes. This can be achieved by lowering the barriers to access health services to the most vulnerable groups and improve mortality and disability rates in the potential workforce.\u0000Methods: The present study was conducted in a remote location defence hospital catering to the health care needs of serving personnel of Indian armed forces and civilians residing in this peripheral area. The basic specialties including Obstetrics, paediatrics, medicine and general surgery are provided at this centre 24*7 by the dedicated medical officers of Indian Armed forces.\u0000Results: Sustainability of care continuously evolves towards becoming a major factor for public healthcare organisations, and more accountability will likely be demanded of managers to deliver on each aspect of its triple bottom line. This study shows that prevention and patient empowerment both carry great potential to attain this objective.\u0000Conclusion: It is necessary to set priorities and act according to available resources and organisational vision. The central threats to sustainability of public health care welfare systems in peripheral hospitals identified, namely the ageing population and rise in chronic diseases. UHC at a meso and micro level, could provide a much better rationale for scholars to evaluate the need for change, and contribute to draft more inclusive sustainable strategies.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 73","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The human ears are specific to an individual because the auricle is also a distinctive feature of a person like other identification features so it is used in various areas of science like forensic medicine, anthropology, and biology. The ear lobule is the last part of the auricle to develop. Methods: This study was carried out among 100 students (50 Male and 50 Female) with age range from 18 to 25 years. The study was conducted in the Department of Anatomy, Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India. Results: Total ear length and ear width were significantly higher in male than female (p value<0.0001) in this study. Lobule length and lobule width of left ear were compared by independent t-test, it was found nonsignificant (p value 0.5706) and significantly higher in male than female (p 0.0017) respectively. The mean value of lobule index of left ear was found significant with higher value in male while the mean value of ear index of left ear was found nonsignificant. Conclusion: Results according to genders who participated in the study where all dimensions (total ear length, ear width, lobule width and lobule index) were higher in male as compared to the female subjects. Although there was no significant difference observed in lobule length and ear index of left ear of male and female subjects.
{"title":"ANTHROPOMETRIC STUDY OF LEFT EXTERNAL EAR: A CROSS-SECTIONAL STUDY IN MEDICAL STUDENTS OF UDAIPUR, RAJASTHAN","authors":"Shrivastava Bhavana, Acharya Sunita, Bharambe Vaishaly Kishore, Medatwal Bhupesh","doi":"10.22159/ijcpr.2024v16i4.5052","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5052","url":null,"abstract":"Objective: The human ears are specific to an individual because the auricle is also a distinctive feature of a person like other identification features so it is used in various areas of science like forensic medicine, anthropology, and biology. The ear lobule is the last part of the auricle to develop.\u0000Methods: This study was carried out among 100 students (50 Male and 50 Female) with age range from 18 to 25 years. The study was conducted in the Department of Anatomy, Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India.\u0000Results: Total ear length and ear width were significantly higher in male than female (p value<0.0001) in this study. Lobule length and lobule width of left ear were compared by independent t-test, it was found nonsignificant (p value 0.5706) and significantly higher in male than female (p 0.0017) respectively. The mean value of lobule index of left ear was found significant with higher value in male while the mean value of ear index of left ear was found nonsignificant.\u0000Conclusion: Results according to genders who participated in the study where all dimensions (total ear length, ear width, lobule width and lobule index) were higher in male as compared to the female subjects. Although there was no significant difference observed in lobule length and ear index of left ear of male and female subjects.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 45","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.4096
Vijay Laxmi Sharma, D. Phirke, Shraddha Khalate
Objective: Mechanical ventilation has been proven to be lifesaving and has significantly reduced mortality in the pediatric population. Despite its life-saving advantages, mechanical ventilation is associated with complications. The study aimed to assess the complications of mechanical ventilation in children up to 12 y of age admitted to the intensive care unit. Methods: The present descriptive, observational, cross-sectional study was conducted on 165 children aged between 0 to 12 y, who were mechanically ventilated for>48 h. Patients were observed daily until the desired result was achieved and were checked to look for complications or negative effects of mechanical ventilation. Results: The majority of subjects belonged to<1 mo of age (77.58%) whereas the maximum number of patients were male (64.24%). In 77.58% of patients, the indication for mechanical ventilation was respiratory failure. The duration of ventilation in 62.43% of patients was>7 d. A total of n=62 (37.58%) patients had ventilator-associated complications. The most common complication was ventilator-associated pneumonia (n=30, 48.38%). The mean hospital stay was found to be 22.88±7.96 d. Whereas the mean hospital stay in patients without complications was significantly less compared to patients with complications (18.57±10.09 d vs 27.19±5.83 d, P=0.00015). The mortality rate was found to be 47.27%. Conclusion: Respiratory cause was the most common indication for mechanical ventilation. The most common complication was ventilator-associated pneumonia. The subjects with complications had prolonged hospital stays.
{"title":"COMPLICATIONS OF MECHANICAL VENTILATION IN CHILDREN UP TO 12 Y OF AGE","authors":"Vijay Laxmi Sharma, D. Phirke, Shraddha Khalate","doi":"10.22159/ijcpr.2024v16i4.4096","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4096","url":null,"abstract":"Objective: Mechanical ventilation has been proven to be lifesaving and has significantly reduced mortality in the pediatric population. Despite its life-saving advantages, mechanical ventilation is associated with complications. The study aimed to assess the complications of mechanical ventilation in children up to 12 y of age admitted to the intensive care unit.\u0000Methods: The present descriptive, observational, cross-sectional study was conducted on 165 children aged between 0 to 12 y, who were mechanically ventilated for>48 h. Patients were observed daily until the desired result was achieved and were checked to look for complications or negative effects of mechanical ventilation.\u0000Results: The majority of subjects belonged to<1 mo of age (77.58%) whereas the maximum number of patients were male (64.24%). In 77.58% of patients, the indication for mechanical ventilation was respiratory failure. The duration of ventilation in 62.43% of patients was>7 d. A total of n=62 (37.58%) patients had ventilator-associated complications. The most common complication was ventilator-associated pneumonia (n=30, 48.38%). The mean hospital stay was found to be 22.88±7.96 d. Whereas the mean hospital stay in patients without complications was significantly less compared to patients with complications (18.57±10.09 d vs 27.19±5.83 d, P=0.00015). The mortality rate was found to be 47.27%.\u0000Conclusion: Respiratory cause was the most common indication for mechanical ventilation. The most common complication was ventilator-associated pneumonia. The subjects with complications had prolonged hospital stays.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.5046
T. M. S. S. S. Vani
Objective: Re-emergent cases of rickettsial disease, the scrub typhus is seen prevalent in cases of acute febrile illness. The objective of this study was to study the magnitude and prevalence of scrub typhus in a tertiary care hospital. Methods: This prospective study was carried on for a period of one year from February 2023 to February 2024. Inpatients between the age group of 16 to 25 y with a triad of fever for more than 5 d of onset with or without an eschar, headache, myalgia and abnormal haematological and biochemical parameters were included in the study. IgM ELISA for scrub typhus was performed. Results: Prevalence of scrub typhus in this study was 9.4% with higher male preponderance of 69.4% in 18 y age group 28.6%. Positive cases were recorded higher during post monsoon season of September 18.9%. Co-infection with dengue and malaria observed in 2 cases and ARDS was the complication in 3 cases. No mortality in this study. Conclusion: It is important to get familiar with the clinical and diagnostic laboratory findings of scrub typhus so as to differentiate it from other aetiologies of acute febrile illness.
{"title":"STUDY OF PREVALENCE OF SCRUB TYPHUS IN ACUTE FEBRILE ILLNESS IN A TERTIARY CARE HOSPITAL, VISAKHAPATNAM","authors":"T. M. S. S. S. Vani","doi":"10.22159/ijcpr.2024v16i4.5046","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5046","url":null,"abstract":"Objective: Re-emergent cases of rickettsial disease, the scrub typhus is seen prevalent in cases of acute febrile illness. The objective of this study was to study the magnitude and prevalence of scrub typhus in a tertiary care hospital.\u0000Methods: This prospective study was carried on for a period of one year from February 2023 to February 2024. Inpatients between the age group of 16 to 25 y with a triad of fever for more than 5 d of onset with or without an eschar, headache, myalgia and abnormal haematological and biochemical parameters were included in the study. IgM ELISA for scrub typhus was performed.\u0000Results: Prevalence of scrub typhus in this study was 9.4% with higher male preponderance of 69.4% in 18 y age group 28.6%. Positive cases were recorded higher during post monsoon season of September 18.9%. Co-infection with dengue and malaria observed in 2 cases and ARDS was the complication in 3 cases. No mortality in this study.\u0000Conclusion: It is important to get familiar with the clinical and diagnostic laboratory findings of scrub typhus so as to differentiate it from other aetiologies of acute febrile illness.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.5010
Ankita Chandwani, K. Modi, Kaushik Shah, Mamta Shah
Objective: The present study aims to develop a novel mouth dissolving tablets containing a combination of herbal extracts and a bioactive constituent and evaluating it for activity against common respiratory diseases (in silico studies). Methods: Docking study was done to provide a scientific foundation, keeping the traditional knowledge as a base. Four trial batches were developed. The final batch was then formulated and various pre and post-compression and assays were performed to evaluate the formation of good quality of product. The final batch was prepared by the method of direct compression and taken for accelerated stability studies. Results: The final batch containing 10 % active ingredients, 7.5 % super-disintegrant and 47 % diluent was found to be stable, easily producible and economic. Conclusion: This research work grasps possibilities for researchers in the development and evaluation of mouth-dissolving tablets with significant bioactive potential against common respiratory diseases.
{"title":"IN SILICO DOCKING STUDY OF HERBAL COMPOSITION AND DEVELOPMENT OF MOUTH DISSOLVING TABLETS FOR COMMON RESPIRATORY DISEASES THEREOF","authors":"Ankita Chandwani, K. Modi, Kaushik Shah, Mamta Shah","doi":"10.22159/ijcpr.2024v16i4.5010","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5010","url":null,"abstract":"Objective: The present study aims to develop a novel mouth dissolving tablets containing a combination of herbal extracts and a bioactive constituent and evaluating it for activity against common respiratory diseases (in silico studies).\u0000Methods: Docking study was done to provide a scientific foundation, keeping the traditional knowledge as a base. Four trial batches were developed. The final batch was then formulated and various pre and post-compression and assays were performed to evaluate the formation of good quality of product. The final batch was prepared by the method of direct compression and taken for accelerated stability studies.\u0000Results: The final batch containing 10 % active ingredients, 7.5 % super-disintegrant and 47 % diluent was found to be stable, easily producible and economic.\u0000Conclusion: This research work grasps possibilities for researchers in the development and evaluation of mouth-dissolving tablets with significant bioactive potential against common respiratory diseases.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.4091
Smriti Sharma, Shaloo Negi, Aditya Kashyap
Objective: This study aims to assess the prevalence, causes, and socio-economic impacts of visual impairment in the Chamba District of Himachal Pradesh, India. It seeks to identify the major factors contributing to visual disability and the role of literacy and employment status in influencing the lives of the visually impaired. Methods: A cross-sectional, hospital-based study was conducted over a period of one year, enrolling patients from the outpatient department of ophthalmology who were applying for visual disability certification. The study utilized a randomized sampling method and a semi-structured interview along with an examination form for data collection. Ethical approval was obtained, and the study adhered to ICMR and Helsinki Declaration guidelines. Participants underwent comprehensive ophthalmic evaluations, and data were analyzed using SPSS version 17.0. Results: Among the 270 participants evaluated, a higher prevalence of visual impairment was observed in males (n=149) compared to females (n=121), particularly within the age group of 21-40 y. The leading causes of visual disability included Corneal Opacity (16.25%), Retinitis Pigmentosa (15.83%), and Congenital Malformation (14.17%). Furthermore, literacy played a crucial role in employment opportunities, with 75.83% of the literate participants being employed, indicating a significant impact on the socio-economic status. Conclusion: The study highlights the multifaceted nature of visual impairment in the Chamba District, emphasizing the need for integrated public health strategies to address the identified challenges. Enhancing preventive measures, improving access to healthcare, and supporting rehabilitation services are essential steps towards mitigating the burden of visual impairment.
{"title":"A STUDY TO EVALUATE THE TYPE AND CAUSE OF BLINDNESS/LOW VISION IN APPLICATIONS FOR BLINDNESS CERTIFICATE PRESENTING IN CHAMBA DISTRICT OF HIMACHAL PRADESH","authors":"Smriti Sharma, Shaloo Negi, Aditya Kashyap","doi":"10.22159/ijcpr.2024v16i4.4091","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4091","url":null,"abstract":"Objective: This study aims to assess the prevalence, causes, and socio-economic impacts of visual impairment in the Chamba District of Himachal Pradesh, India. It seeks to identify the major factors contributing to visual disability and the role of literacy and employment status in influencing the lives of the visually impaired.\u0000Methods: A cross-sectional, hospital-based study was conducted over a period of one year, enrolling patients from the outpatient department of ophthalmology who were applying for visual disability certification. The study utilized a randomized sampling method and a semi-structured interview along with an examination form for data collection. Ethical approval was obtained, and the study adhered to ICMR and Helsinki Declaration guidelines. Participants underwent comprehensive ophthalmic evaluations, and data were analyzed using SPSS version 17.0.\u0000Results: Among the 270 participants evaluated, a higher prevalence of visual impairment was observed in males (n=149) compared to females (n=121), particularly within the age group of 21-40 y. The leading causes of visual disability included Corneal Opacity (16.25%), Retinitis Pigmentosa (15.83%), and Congenital Malformation (14.17%). Furthermore, literacy played a crucial role in employment opportunities, with 75.83% of the literate participants being employed, indicating a significant impact on the socio-economic status.\u0000Conclusion: The study highlights the multifaceted nature of visual impairment in the Chamba District, emphasizing the need for integrated public health strategies to address the identified challenges. Enhancing preventive measures, improving access to healthcare, and supporting rehabilitation services are essential steps towards mitigating the burden of visual impairment.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.5026
Ksk Divya, Bnv Mounisha, R. V. Sowmya
Objective: The present study aimed to determine the prevalence of PCOS among young adults attended to medical OP in a Tertiary care teaching hospital. Materials: It is a retrospective study conducted in a Tertiary care teaching hospital, Visakhapatnam using existing records in the Department of Obstetrics and Gynaecology. The study was conducted from July 2021 to July 2023. The study population includes young adults of age in between 18-30 y. PCOS was defined by Rotterdam's criteria having presence of any two of the three features. Hormonal assays were conducted using immunoradiometric assay for TSH, LH, FSH. Results: Majority of the PCOS cases 39% were reported in the age group of 26-30 Y. Among the 100 cases reported, the majority of them are reported with menstrual irregularity 62%. However, it was identified from the results that the mean values of cholesterol and triglycerides levels are quite higher suggested hyperlipidemia. The hormonal levels of TSH, LH and FSH were normal. Conclusion: Although the overall frequency of PCOS is low and evaluating PCOS in young adults can be difficult, the condition is becoming more common at this age. Changes in lifestyle are essential at this age to avoid long-term metabolic and reproductive issues.
{"title":"PREVALENCE OF POLYCYSTIC OVARIAN SYNDROME AMONG YOUNG WOMEN WHO ATTENDED TERTIARY CARE HOSPITAL, VISAKHAPATNAM","authors":"Ksk Divya, Bnv Mounisha, R. V. Sowmya","doi":"10.22159/ijcpr.2024v16i4.5026","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5026","url":null,"abstract":"Objective: The present study aimed to determine the prevalence of PCOS among young adults attended to medical OP in a Tertiary care teaching hospital.\u0000Materials: It is a retrospective study conducted in a Tertiary care teaching hospital, Visakhapatnam using existing records in the Department of Obstetrics and Gynaecology. The study was conducted from July 2021 to July 2023. The study population includes young adults of age in between 18-30 y. PCOS was defined by Rotterdam's criteria having presence of any two of the three features. Hormonal assays were conducted using immunoradiometric assay for TSH, LH, FSH.\u0000Results: Majority of the PCOS cases 39% were reported in the age group of 26-30 Y. Among the 100 cases reported, the majority of them are reported with menstrual irregularity 62%. However, it was identified from the results that the mean values of cholesterol and triglycerides levels are quite higher suggested hyperlipidemia. The hormonal levels of TSH, LH and FSH were normal.\u0000Conclusion: Although the overall frequency of PCOS is low and evaluating PCOS in young adults can be difficult, the condition is becoming more common at this age. Changes in lifestyle are essential at this age to avoid long-term metabolic and reproductive issues.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.5021
Yogesh Yadav, Jyoti Choudhary, Mohammed Nasir Khan
Objective: This study aimed to identify drug-resistant tuberculosis cases and treatment results. Because it is one of the few studies that have looked at the results of TB treatment among children in the nation, this one was noteworthy. Methods: Drug-resistant cases of paediatric TB were recruited from various districts of Western Rajasthan. Drug resistance in Mycobacterium tuberculosis was detected by line Probe Assay. The cases were followed up for treatment. Results: A total of 41 drug-resistant TB cases were evaluated. Out of 41, 21 were rifampicin mono-resistant, 8 were isoniazid mono-resistant, MDR and pre-XDR were 5 each, and XDR cases were 2. 19 cases were successfully cured and there was one death reported during treatment. Conclusion: Cure rate of paediatric TB is less than 50% in our region. Adherence to treatment and contact isolation are crucial to increase cure rate and decrease the incidence of drug-resistant TB.
{"title":"TREATMENT OUTCOME OF TUBERCULOSIS CASES AMONG PAEDIATRIC PATIENTS IN WESTERN RAJASTHAN","authors":"Yogesh Yadav, Jyoti Choudhary, Mohammed Nasir Khan","doi":"10.22159/ijcpr.2024v16i4.5021","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.5021","url":null,"abstract":"Objective: This study aimed to identify drug-resistant tuberculosis cases and treatment results. Because it is one of the few studies that have looked at the results of TB treatment among children in the nation, this one was noteworthy.\u0000Methods: Drug-resistant cases of paediatric TB were recruited from various districts of Western Rajasthan. Drug resistance in Mycobacterium tuberculosis was detected by line Probe Assay. The cases were followed up for treatment.\u0000Results: A total of 41 drug-resistant TB cases were evaluated. Out of 41, 21 were rifampicin mono-resistant, 8 were isoniazid mono-resistant, MDR and pre-XDR were 5 each, and XDR cases were 2. 19 cases were successfully cured and there was one death reported during treatment.\u0000Conclusion: Cure rate of paediatric TB is less than 50% in our region. Adherence to treatment and contact isolation are crucial to increase cure rate and decrease the incidence of drug-resistant TB.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 38","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-15DOI: 10.22159/ijcpr.2024v16i4.4092
Aditya Kashyap, Smriti Sharma, Shaloo Negi
Objective: This study aims to investigate the demographic characteristics, occupational background, and injury management of patients presenting with ocular trauma involving metallic corneal foreign bodies (FBs). Methods: A cross-sectional study was conducted at the outpatient clinic of Ophthalmology at Pt JLNGMC, Chamba. Data were collected from consecutive patients over three months. Demographic data, including age, gender, and education level, were analyzed alongside occupational background, injury context, and protective measures. Statistical analysis was performed using SPSS version 17.0, with descriptive statistics utilized to present the results. Results: The study revealed a predominance of young males (66%) in the 14-29 age group, with the metalwork industry (47%) being the primary sector where injuries occurred, mainly during metal grinding activities (53%). Lack of protective measures, such as temporary removal of eyewear (39%), contributed to the injuries. Notably, 54% of patients did not attempt self-removal of FBs. Superficial corneal FBs accounted for 45% of cases, indicating significant potential for severe injury. Conclusion: The findings underscore the urgent need for enhanced safety education, rigorous enforcement of protective eyewear usage, and targeted interventions in high-risk occupational sectors to mitigate the prevalence and severity of corneal FB injuries. Addressing these challenges is crucial for preserving vision, reducing healthcare costs, and improving occupational health and safety standards.
{"title":"A STUDY TO EVALUATE THE DEMOGRAPHIC PATTERN OF THE INJURY CAUSED BY METALLIC CORNEAL FOREIGN BODY AND ITS OUTCOME AFTER TREATMENT","authors":"Aditya Kashyap, Smriti Sharma, Shaloo Negi","doi":"10.22159/ijcpr.2024v16i4.4092","DOIUrl":"https://doi.org/10.22159/ijcpr.2024v16i4.4092","url":null,"abstract":"Objective: This study aims to investigate the demographic characteristics, occupational background, and injury management of patients presenting with ocular trauma involving metallic corneal foreign bodies (FBs).\u0000Methods: A cross-sectional study was conducted at the outpatient clinic of Ophthalmology at Pt JLNGMC, Chamba. Data were collected from consecutive patients over three months. Demographic data, including age, gender, and education level, were analyzed alongside occupational background, injury context, and protective measures. Statistical analysis was performed using SPSS version 17.0, with descriptive statistics utilized to present the results.\u0000Results: The study revealed a predominance of young males (66%) in the 14-29 age group, with the metalwork industry (47%) being the primary sector where injuries occurred, mainly during metal grinding activities (53%). Lack of protective measures, such as temporary removal of eyewear (39%), contributed to the injuries. Notably, 54% of patients did not attempt self-removal of FBs. Superficial corneal FBs accounted for 45% of cases, indicating significant potential for severe injury.\u0000Conclusion: The findings underscore the urgent need for enhanced safety education, rigorous enforcement of protective eyewear usage, and targeted interventions in high-risk occupational sectors to mitigate the prevalence and severity of corneal FB injuries. Addressing these challenges is crucial for preserving vision, reducing healthcare costs, and improving occupational health and safety standards.","PeriodicalId":13875,"journal":{"name":"International Journal of Current Pharmaceutical Research","volume":" 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141833551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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