Pub Date : 2021-11-01DOI: 10.22271/flora.2021.v9.i6a.781
Febitha M Das, Aruna Mv
Morinda citrifolia is used traditionally for the treatment of infectious diseases. This study aims to investigate phytochemical screening and examines the antioxidant and antibacterial property of leaves. The shade dried leaf powder was extracted serially using hexane, acetone, and water. All three extracts were subjected to phytochemical screenings and only water extract is subjected to antibacterial and antioxidant analysis. Preliminary phytochemical screening was carried out by different chemical tests. Amino acid, Carbohydrate, Protein were the primary metabolites found to be present. The Alkaloids, Flavonoids, Terpenoids, Steroids, Saponins, Phenol, Tannin, and Cardiac glycosides showed to be present as the secondary metabolites. The terpenoids were found only in acetone extract. The evaluation of antibacterial activity of the aqueous extract of Morinda citrifolia against Escherichia coli and Pseudomonas aeruginosa at concentrations 10, 50,100μl. The bacterial strains are sub-cultured on nutrient broth. The aqueous extract of Morinda citrifolia shows maximum antibacterial activity in 100μl concentrations, in Pseudomonas aeruginosa it will be 61.46% and in the case of Escherichia coli 52.24%. The antioxidant activity of aqueous extract of Morinda citrifolia was carried out by 2,2-diphenyl-1picrylhydrazyl (DPPH) assay. Different concentration of the extract was taken and the percentage of inhibition was calculated. Maximum radical scavenging activity was observed in 100μl concentration i.e. 68.94% and minimum in 50μl concentration. i.e., 49.47%. So as the concentration increases the antioxidant activity also increases. The data generated as a result of this investigation has provided the scientific basis for its use as therapeutic in traditional medicine.
{"title":"Phytochemical screening, antioxidant and antibacterial activity of leaf extract of Morinda citrifolia L. against Escherichia coli & Pseudomonas aeruginosa","authors":"Febitha M Das, Aruna Mv","doi":"10.22271/flora.2021.v9.i6a.781","DOIUrl":"https://doi.org/10.22271/flora.2021.v9.i6a.781","url":null,"abstract":"Morinda citrifolia is used traditionally for the treatment of infectious diseases. This study aims to investigate phytochemical screening and examines the antioxidant and antibacterial property of leaves. The shade dried leaf powder was extracted serially using hexane, acetone, and water. All three extracts were subjected to phytochemical screenings and only water extract is subjected to antibacterial and antioxidant analysis. Preliminary phytochemical screening was carried out by different chemical tests. Amino acid, Carbohydrate, Protein were the primary metabolites found to be present. The Alkaloids, Flavonoids, Terpenoids, Steroids, Saponins, Phenol, Tannin, and Cardiac glycosides showed to be present as the secondary metabolites. The terpenoids were found only in acetone extract. The evaluation of antibacterial activity of the aqueous extract of Morinda citrifolia against Escherichia coli and Pseudomonas aeruginosa at concentrations 10, 50,100μl. The bacterial strains are sub-cultured on nutrient broth. The aqueous extract of Morinda citrifolia shows maximum antibacterial activity in 100μl concentrations, in Pseudomonas aeruginosa it will be 61.46% and in the case of Escherichia coli 52.24%. The antioxidant activity of aqueous extract of Morinda citrifolia was carried out by 2,2-diphenyl-1picrylhydrazyl (DPPH) assay. Different concentration of the extract was taken and the percentage of inhibition was calculated. Maximum radical scavenging activity was observed in 100μl concentration i.e. 68.94% and minimum in 50μl concentration. i.e., 49.47%. So as the concentration increases the antioxidant activity also increases. The data generated as a result of this investigation has provided the scientific basis for its use as therapeutic in traditional medicine.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84975840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-11-01DOI: 10.22271/flora.2021.v9.i6a.784
Shreyasi Halder, K. Khaled
{"title":"Anti-nutritional profiling from the edible flowers of Allium cepa, Cucurbita maxima and Carica papaya and its comparison with other commonly consumed flowers","authors":"Shreyasi Halder, K. Khaled","doi":"10.22271/flora.2021.v9.i6a.784","DOIUrl":"https://doi.org/10.22271/flora.2021.v9.i6a.784","url":null,"abstract":"","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89801179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.22271/flora.2020.v8.i6a.706
D. Hemalika, U. Chandrika
Dengue viral infections have shown to infect 390 million individuals annually, causing severe clinical disease in the form of dengue hemorrhagic fever (DHF). The World Health Organization (WHO) has identified dengue as one of the top ten global health threats in year 2019. There is currently no specific drug for treatment of this potentially fatal disease. Although a vaccine was recently licensed to prevent infection, it was found to have poor efficacy against some dengue virus (DENV) serotypes. Therefore, researchers are now seeking herbal treatments for the dengue based on ethno medical usage. This review provides information on herbal plants commonly found in tropical countries which documented for anti-dengue properties by enough scientific experimental details. We hope to encourage more studies on plants described in this review for the development of new therapeutic targets for the management of dengue fever.
{"title":"Anti-dengue effects of medicinal plants: A review","authors":"D. Hemalika, U. Chandrika","doi":"10.22271/flora.2020.v8.i6a.706","DOIUrl":"https://doi.org/10.22271/flora.2020.v8.i6a.706","url":null,"abstract":"Dengue viral infections have shown to infect 390 million individuals annually, causing severe clinical disease in the form of dengue hemorrhagic fever (DHF). The World Health Organization (WHO) has identified dengue as one of the top ten global health threats in year 2019. There is currently no specific drug for treatment of this potentially fatal disease. Although a vaccine was recently licensed to prevent infection, it was found to have poor efficacy against some dengue virus (DENV) serotypes. Therefore, researchers are now seeking herbal treatments for the dengue based on ethno medical usage. This review provides information on herbal plants commonly found in tropical countries which documented for anti-dengue properties by enough scientific experimental details. We hope to encourage more studies on plants described in this review for the development of new therapeutic targets for the management of dengue fever.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86387123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.22271/flora.2020.v8.i6a.705
Mohd Aleem, I. Khan, Fayyaz Ahmad Shakshaz, Nusra Akbari, Daraksha Anwar
Antibiotic resistance in every corner of the planet is growing to dangerously high levels. New mechanisms of resistance are emerging and spreading globally which threatens our ability to treat common infectious diseases. Many scientists documented some plants having antimicrobial properties. Zingiber officinale Roscoe (ZO), the most recognised member of Zingiber, is one of them. This review aims to validate the antimicrobial activity of ginger. The information and data on ZO were collated from various resources like ethnobotanical textbooks, Pub Med, Google Scholar, Science Direct, Web of Science, and Scopus. ZO has many medicinal, nutritional and ethnomedical values and is commonly used as a spice, flavouring agent and herbal remedy worldwide. In addition to giving ginger its pungent aroma, volatile oil gingerol and other pungent principles are the most medically potent since they inhibit the production of prostaglandin and leukotriene, which are chemicals that affect blood flow and inflammation. Traditionally, it has been used as an herbal remedy for centuries in Ayurvedic, Tibb-Unani, Chinese, Islamic, Africans, the Caribbean and many other medicinal systems to cure a variety of diseases like throat infections, asthma, inflammation, dyspepsia, loss of appetite, palpitation, constipation and indigestion, colds, arthritis, nausea, hypertension, migraines, and many more. It has a high proportion of α-Zingiberene, β-sesquiphellandrene, (E,E)- α-farnesene, geranial and ar-curcumene. The ZO extracts, essential oil and chemical constituents exhibited antimicrobial, anticonvulsant, analgesic, anti-inflammatory, antiulcer, immunomodulatory, and other beneficial activities. The research suggests that there are marked antimicrobial activities in the ginger that could be beneficial and applied in various research areas, such as the pharmaceutical and food industries. To understand the molecular mechanisms by which these effects are exerted, more research may be required.
在地球的每一个角落，抗生素耐药性正在增长到危险的高水平。新的耐药机制正在出现并在全球蔓延，威胁到我们治疗常见传染病的能力。许多科学家记录了一些具有抗菌特性的植物。Zingiber officinale Roscoe (ZO)是Zingiber中最知名的成员之一。本文旨在验证生姜的抗菌活性。关于ZO的信息和数据是从民族植物学教科书、Pub Med、Google Scholar、Science Direct、Web of Science和Scopus等多种资源中整理的。ZO具有许多药用、营养和民族医学价值，在世界范围内通常用作香料、调味剂和草药。除了赋予生姜辛辣的香气，姜辣素和其他刺激性成分在医学上是最有效的，因为它们抑制前列腺素和白三烯的产生，这是影响血液流动和炎症的化学物质。传统上，几个世纪以来，它一直被用作阿育吠陀、蒂布-乌纳尼、中国、伊斯兰、非洲、加勒比和许多其他医疗系统的草药，用于治疗各种疾病，如喉咙感染、哮喘、炎症、消化不良、食欲不振、心悸、便秘和消化不良、感冒、关节炎、恶心、高血压、偏头痛等等。它含有高比例的α-姜黄烯、β-倍半黄烯、(E,E)- α-法尔尼烯、香樟烯和ar-姜黄烯。ZO提取物、精油和化学成分具有抗菌、抗惊厥、镇痛、抗炎、抗溃疡、免疫调节等有益活性。研究表明，生姜具有明显的抗菌活性，可用于制药和食品工业等各个研究领域。为了了解这些作用产生的分子机制，可能需要进行更多的研究。
{"title":"Botany, phytochemistry and antimicrobial activity of ginger (Zingiber officinale): A review","authors":"Mohd Aleem, I. Khan, Fayyaz Ahmad Shakshaz, Nusra Akbari, Daraksha Anwar","doi":"10.22271/flora.2020.v8.i6a.705","DOIUrl":"https://doi.org/10.22271/flora.2020.v8.i6a.705","url":null,"abstract":"Antibiotic resistance in every corner of the planet is growing to dangerously high levels. New mechanisms of resistance are emerging and spreading globally which threatens our ability to treat common infectious diseases. Many scientists documented some plants having antimicrobial properties. Zingiber officinale Roscoe (ZO), the most recognised member of Zingiber, is one of them. This review aims to validate the antimicrobial activity of ginger. The information and data on ZO were collated from various resources like ethnobotanical textbooks, Pub Med, Google Scholar, Science Direct, Web of Science, and Scopus. ZO has many medicinal, nutritional and ethnomedical values and is commonly used as a spice, flavouring agent and herbal remedy worldwide. In addition to giving ginger its pungent aroma, volatile oil gingerol and other pungent principles are the most medically potent since they inhibit the production of prostaglandin and leukotriene, which are chemicals that affect blood flow and inflammation. Traditionally, it has been used as an herbal remedy for centuries in Ayurvedic, Tibb-Unani, Chinese, Islamic, Africans, the Caribbean and many other medicinal systems to cure a variety of diseases like throat infections, asthma, inflammation, dyspepsia, loss of appetite, palpitation, constipation and indigestion, colds, arthritis, nausea, hypertension, migraines, and many more. It has a high proportion of α-Zingiberene, β-sesquiphellandrene, (E,E)- α-farnesene, geranial and ar-curcumene. The ZO extracts, essential oil and chemical constituents exhibited antimicrobial, anticonvulsant, analgesic, anti-inflammatory, antiulcer, immunomodulatory, and other beneficial activities. The research suggests that there are marked antimicrobial activities in the ginger that could be beneficial and applied in various research areas, such as the pharmaceutical and food industries. To understand the molecular mechanisms by which these effects are exerted, more research may be required.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86997033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-10-08DOI: 10.21203/rs.3.rs-86484/v1
K. Hamwenye, Helena Shindaadhi, E. Sivhute, P. H. Hal, C. Samundengu
BackgroundHibiscus sabdariffa is popularly known as food and herbal drink with numerous health benefits. The phytochemical compounds present in Hibiscus sabdariffa calyces are important in developing nutraceutical foods. In this study hibiscus jam and yoghurt were produced from dried hibiscus calyces’ powder.MethodsThe phytochemical content and antioxidant activity of these products were then analysed in terms of Total phenolic content (TPC), Total flavonoid content (TFC), Condensed tannins (CT) and DPPH Scavenging activity.ResultsThe results showed the presence of all phytochemical compounds (TPC, TFC, CT) and antioxidant activity in all Hibiscus sabdariffa products. The hibiscus calyces powder showed the highest phytochemical contents of 35.24 mg GAE. g -1 , 0.91 mg QE. g -1 , 2.85 mg CAE. g -1 and 48.2 % inhibition for TPC, TFC, CT and DPPH Scavenging activity, respectively. Hibiscus jam and Hibiscus yoghurt had phytochemical contents of 6.44 and 4.81 mg GAE. g -1 , 0.19 & 0.24 mg QE. g -1 , 1.40 & 0.66 mg CAE. g -1 and 26.2 & 39.3 % inhibition for TPC, TFC, TC and DPPH Scavenging activity, respectively.ConclusionsThe results of the current study showed that there is potential in using Hibiscus sabdariffa to develop functional foods.
{"title":"Phytochemical Evaluation of Hibiscus Sabdariffa Powder, Jam and Yoghurt","authors":"K. Hamwenye, Helena Shindaadhi, E. Sivhute, P. H. Hal, C. Samundengu","doi":"10.21203/rs.3.rs-86484/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-86484/v1","url":null,"abstract":"\u0000 BackgroundHibiscus sabdariffa is popularly known as food and herbal drink with numerous health benefits. The phytochemical compounds present in Hibiscus sabdariffa calyces are important in developing nutraceutical foods. In this study hibiscus jam and yoghurt were produced from dried hibiscus calyces’ powder.MethodsThe phytochemical content and antioxidant activity of these products were then analysed in terms of Total phenolic content (TPC), Total flavonoid content (TFC), Condensed tannins (CT) and DPPH Scavenging activity.ResultsThe results showed the presence of all phytochemical compounds (TPC, TFC, CT) and antioxidant activity in all Hibiscus sabdariffa products. The hibiscus calyces powder showed the highest phytochemical contents of 35.24 mg GAE. g -1 , 0.91 mg QE. g -1 , 2.85 mg CAE. g -1 and 48.2 % inhibition for TPC, TFC, CT and DPPH Scavenging activity, respectively. Hibiscus jam and Hibiscus yoghurt had phytochemical contents of 6.44 and 4.81 mg GAE. g -1 , 0.19 & 0.24 mg QE. g -1 , 1.40 & 0.66 mg CAE. g -1 and 26.2 & 39.3 % inhibition for TPC, TFC, TC and DPPH Scavenging activity, respectively.ConclusionsThe results of the current study showed that there is potential in using Hibiscus sabdariffa to develop functional foods.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"86 1","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2020-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75841413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi Xuan, Dalian Ding, Weijun Xuan, Liyi Huang, Junbo Tang, Yulong Wei, Sizhong Chen, Michael R Hamblin
Age-related hearing loss (AHL) or presbycusis is steadily increasing due to the overall aging of the Chinese population. Traditional Chinese medicine (TCM) has long been used to prevent and treat deafness, but its effectiveness and mechanism of action are still uncertain. The present study tested a TCM preparation called "Jian Er" in a mouse model of prebycusis.
{"title":"A traditional Chinese medicine compound (Jian Er) for presbycusis in a mouse model: Reduction of apoptosis and protection of cochlear sensorineural cells and hearing.","authors":"Yi Xuan, Dalian Ding, Weijun Xuan, Liyi Huang, Junbo Tang, Yulong Wei, Sizhong Chen, Michael R Hamblin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Age-related hearing loss (AHL) or presbycusis is steadily increasing due to the overall aging of the Chinese population. Traditional Chinese medicine (TCM) has long been used to prevent and treat deafness, but its effectiveness and mechanism of action are still uncertain. The present study tested a TCM preparation called \"Jian Er\" in a mouse model of prebycusis.</p>","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"6 6","pages":"127-135"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6936738/pdf/nihms-1012046.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37503456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-11-01DOI: 10.22271/FLORA.2016.V4.I6C.03
Abderrahim Benslama, Abdenassar Harrar
The aim of this study is to evaluate antioxidant activity of aqueous (Aq.E) and methanolic (Met.E) extracts of Zygophyllum album L. (Zygophyllaceae) and Arthrophytum scoparium (Chenpodiacea), two medicinal plant from Algerian Sahara used in traditional pharmacopoeia. The results showed that Aq.E have the heights yields 24% and 22.3% for Z. album and A. scoparium respectively. Qualitative analysis of showed that the Met.E of Z. album of had the highest amount of polyphenols (202.26±4.73 μg GAE/mg E) and flavonoids (15.77±0.94 μg QE/mg E). The antioxidant activity of extracts was evaluated by 2, 2’-diphenyl-1-picrylhydrazyl (DPPH) and reducing power assay. Results showed that the extracts of A. scoparium. Have the highest free radical scavenger activity in DPPH test (EC50=0.096±0.001 and 0.108±0.002 mg/ml for Met.E and Aq.E respectively). In addition, the results of reducing power assay demonstrated that Met.E of Z. album had the highest effect with 2399.65±12.31 μg ascorbic acid equivalent/mg E.Our results showed that the methanolic extract reported a considerable free radicals scavenging activity and reducing effect, may be due to their richness on polyphenols and flavonoids.
{"title":"Free radicals scavenging activity and reducing power of two Algerian Sahara medicinal plants extracts","authors":"Abderrahim Benslama, Abdenassar Harrar","doi":"10.22271/FLORA.2016.V4.I6C.03","DOIUrl":"https://doi.org/10.22271/FLORA.2016.V4.I6C.03","url":null,"abstract":"The aim of this study is to evaluate antioxidant activity of aqueous (Aq.E) and methanolic (Met.E) extracts of Zygophyllum album L. (Zygophyllaceae) and Arthrophytum scoparium (Chenpodiacea), two medicinal plant from Algerian Sahara used in traditional pharmacopoeia. The results showed that Aq.E have the heights yields 24% and 22.3% for Z. album and A. scoparium respectively. Qualitative analysis of showed that the Met.E of Z. album of had the highest amount of polyphenols (202.26±4.73 μg GAE/mg E) and flavonoids (15.77±0.94 μg QE/mg E). The antioxidant activity of extracts was evaluated by 2, 2’-diphenyl-1-picrylhydrazyl (DPPH) and reducing power assay. Results showed that the extracts of A. scoparium. Have the highest free radical scavenger activity in DPPH test (EC50=0.096±0.001 and 0.108±0.002 mg/ml for Met.E and Aq.E respectively). In addition, the results of reducing power assay demonstrated that Met.E of Z. album had the highest effect with 2399.65±12.31 μg ascorbic acid equivalent/mg E.Our results showed that the methanolic extract reported a considerable free radicals scavenging activity and reducing effect, may be due to their richness on polyphenols and flavonoids.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"116 1","pages":"158-161"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79367368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2016-05-01DOI: 10.22271/FLORA.2016.V4.I3.05
Krishnasis Chakraborty, A. Shivakumar, Sundaram Ramachandran
Herbal medicines have been used from years throughout the world; especially in India, herbal medicines are in high demand. The use of herbal medicines has increased because of their ability to treat different diseases with fewer side effects. The development of novel drug delivery system (NDDS) is of considerable importance to overcome various constraints like poor bioavailability, in vivo stability, aqueous insolubility, intestinal absorption and unspecific site of action. The integration of the Nano science as a NDDS in traditional system of medicine enriches the potential of herbal drugs for treating chronic diseases such as cancer and ravaging diseases. The synthesis of nanoparticles can be achieved by adopting the novel methodologies such as Polymer nanoparticle, Magnetic nanoparticle and Metallic nanoparticle depending on characteristic of the nanoparticles. The advanced technologies will shed lights for characterizing the nanoparticles to determine the toxicity profiles for their physical and chemical properties. This review article will provide a brief discussion of Nanoparticles synthesis, characterization by various techniques for production and its future impact of nanotechnology on smart herbal drugs.
{"title":"Nano-technology in herbal medicines: A review","authors":"Krishnasis Chakraborty, A. Shivakumar, Sundaram Ramachandran","doi":"10.22271/FLORA.2016.V4.I3.05","DOIUrl":"https://doi.org/10.22271/FLORA.2016.V4.I3.05","url":null,"abstract":"Herbal medicines have been used from years throughout the world; especially in India, herbal medicines are in high demand. The use of herbal medicines has increased because of their ability to treat different diseases with fewer side effects. The development of novel drug delivery system (NDDS) is of considerable importance to overcome various constraints like poor bioavailability, in vivo stability, aqueous insolubility, intestinal absorption and unspecific site of action. The integration of the Nano science as a NDDS in traditional system of medicine enriches the potential of herbal drugs for treating chronic diseases such as cancer and ravaging diseases. The synthesis of nanoparticles can be achieved by adopting the novel methodologies such as Polymer nanoparticle, Magnetic nanoparticle and Metallic nanoparticle depending on characteristic of the nanoparticles. The advanced technologies will shed lights for characterizing the nanoparticles to determine the toxicity profiles for their physical and chemical properties. This review article will provide a brief discussion of Nanoparticles synthesis, characterization by various techniques for production and its future impact of nanotechnology on smart herbal drugs.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"62 1","pages":"21-27"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82360398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-10-01DOI: 10.22271/FLORA.2015.V3.I4.08
P. Biswajit
The paper reports 94 plant species under 83 genera and 44 families of which 34 are dicot, 7 monocot and 3 pteridophyta. The plant species constitute 34 herbs, 10 shrubs, 9 climbers and 41 tree species. There are no gymnosperm species found in the forest. The forests are dry deciduous type and dominated by Rakta Chandan (Pterocarpus santalinus L.). In this forest 737 red sandal trees were present.
{"title":"Labanyagada: The protected red sandal forest of Gajapati district, Odisha, India","authors":"P. Biswajit","doi":"10.22271/FLORA.2015.V3.I4.08","DOIUrl":"https://doi.org/10.22271/FLORA.2015.V3.I4.08","url":null,"abstract":"The paper reports 94 plant species under 83 genera and 44 families of which 34 are dicot, 7 monocot and 3 pteridophyta. The plant species constitute 34 herbs, 10 shrubs, 9 climbers and 41 tree species. There are no gymnosperm species found in the forest. The forests are dry deciduous type and dominated by Rakta Chandan (Pterocarpus santalinus L.). In this forest 737 red sandal trees were present.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"1 1","pages":"35-40"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75785803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-04-01DOI: 10.22271/FLORA.2015.V3.I1.03
Amal K. Maji, Pratim Banerji
Chelidonium majus L. (Papaveraceae) is a medicinal herb used in various traditional systems of medicine to treat ulcer, cancer, oral infection, liver disorders, chronic bronchitis, asthma, etc. Different parts of this plant contain numerous therapeutically important alkaloidal constituents such as chelidonine, chelerythrine, sanguinarine, berberine and so on. The plant and its active compounds exhibit a wide range of pharmacological activities. The plants has long history of therapeutic use in medicines without any toxic effect. Today it is one of the important components of some pharmaceutical preparations. Consumption of C. majus preparations possesses toxic effects on the liver although the effect becomes controversial with its hepatoprotective effect. Numerous active constituents of C. majus interact with various drug metabolizing enzymes that mimic possible interactions of this herb with the conventional drugs. This review provides detailed phytochemical, pharmacological and toxicological information of C. majus along with mechanisms of action of its various active compounds on different aspects of pharmacology. This review also highlights plausible drug interaction of its various active compounds and the future prospect of this herb.
{"title":"Chelidonium majus L. (Greater celandine) – A Review on its Phytochemical and Therapeutic Perspectives","authors":"Amal K. Maji, Pratim Banerji","doi":"10.22271/FLORA.2015.V3.I1.03","DOIUrl":"https://doi.org/10.22271/FLORA.2015.V3.I1.03","url":null,"abstract":"Chelidonium majus L. (Papaveraceae) is a medicinal herb used in various traditional systems of medicine to treat ulcer, cancer, oral infection, liver disorders, chronic bronchitis, asthma, etc. Different parts of this plant contain numerous therapeutically important alkaloidal constituents such as chelidonine, chelerythrine, sanguinarine, berberine and so on. The plant and its active compounds exhibit a wide range of pharmacological activities. The plants has long history of therapeutic use in medicines without any toxic effect. Today it is one of the important components of some pharmaceutical preparations. Consumption of C. majus preparations possesses toxic effects on the liver although the effect becomes controversial with its hepatoprotective effect. Numerous active constituents of C. majus interact with various drug metabolizing enzymes that mimic possible interactions of this herb with the conventional drugs. This review provides detailed phytochemical, pharmacological and toxicological information of C. majus along with mechanisms of action of its various active compounds on different aspects of pharmacology. This review also highlights plausible drug interaction of its various active compounds and the future prospect of this herb.","PeriodicalId":14070,"journal":{"name":"International Journal of Herbal Medicine","volume":"3 1","pages":"10-27"},"PeriodicalIF":0.0,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86740465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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