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A review on medicinal plants used in the treatment of rheumatoid arthritis 类风湿性关节炎的药用植物研究进展
Pub Date : 2023-03-07 DOI: 10.46796/ijpc.v4i1.422
S. R, Ruchitha J U, Sagheer Ahmed Syed, R. M, Sahana N
Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation in the joints. It usually attacks synovial joints and cartilage, causing joint destruction and long-term disability. Herbal medicines are becoming more popular in recent years due to their safety, efficacy, and ease of access. There have been numerous reports of medicinal plants being used to treat Rheumatoid arthritis. The current review summarises the use of medicinal plants in the treatment of rheumatoid arthritis.
类风湿性关节炎是一种引起关节慢性炎症的自身免疫性疾病。它通常攻击滑膜关节和软骨,造成关节破坏和长期残疾。近年来,草药因其安全性、有效性和易于获取而变得越来越受欢迎。有许多药用植物被用来治疗类风湿性关节炎的报道。现就药用植物在类风湿关节炎治疗中的应用作一综述。
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引用次数: 0
A review on phytosomes as innovative delivery systems for phytochemicals 磷脂小体作为植物化学物质的新型传递系统的研究进展
Pub Date : 2023-02-19 DOI: 10.46796/ijpc.v4i1.416
Anil Kumar Tallam, A. Sahithi, Mohana Vamsi Nuli
Nowadays, medicinal herbs and their phytochemicals have emerged as great therapeutic options for many disorders. However, poor bioavailability and selectivity might limit their clinical application. Therefore, bioavailability is considered a notable challenge to improving bio-efficacy in transporting dietary phytochemicals. Different methods have been proposed for generating effective carrier systems to enhance the bioavailability of Phytochemicals. Among them, nano-vesicles have been introduced as promising candidates for the delivery of insoluble phytochemicals. Due to the easy preparation of the bilayer vesicles and their adaptability, they have been widely used and approved by the scientific literature. The first part of the review is focused on introducing pyrosomes technology as well as its applications, with emphasis on principles of formulations and characterization. The second part provides a wide overview of the biological activities of commercial and non-commercial pyrosomes, divided by systems and related pathologies. These results confirm the greater effectiveness of pyrosomes, both in terms of biological activity or reduced dosage, high-lighting curcumin, and Silymarin as the most formulated compounds. Finally, we describe the promising clinical and experimental findings regarding the applications of pyrosomes. The conclusion of this study encourages the researchers to transfer their knowledge from laboratories to the market, for further development of these products.
如今,草药及其植物化学物质已成为许多疾病的重要治疗选择。然而,较差的生物利用度和选择性可能限制其临床应用。因此,生物利用度被认为是提高膳食植物化学物质运输生物功效的重要挑战。为了提高植物化学物质的生物利用度,已经提出了不同的方法来产生有效的载体系统。其中,纳米囊泡已被介绍为输送不溶性植物化学物质的有希望的候选者。由于双层囊泡制备简单,适应性强,得到了科学文献的广泛应用和认可。第一部分主要介绍了火小体技术及其应用,重点介绍了其配方原理和表征。第二部分提供了商业和非商业火体生物活性的广泛概述,按系统和相关病理划分。这些结果证实,无论是在生物活性方面还是在减少剂量方面,火小体都具有更大的有效性,高光姜黄素和水飞蓟素是配方最多的化合物。最后,我们描述了有关火小体应用的临床和实验结果。这项研究的结论鼓励研究人员将他们的知识从实验室转移到市场,以进一步开发这些产品。
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引用次数: 1
A review on traditional uses and pharmacological action of psidium guajava linn plant 瓜爪哇番石榴的传统用途及药理作用综述
Pub Date : 2022-12-07 DOI: 10.46796/ijpc.v3i4.369
Bharathi D R, Kiran Kumar Marati, M. C, Ajay B V, M. V, R. M, R. B.
Traditional medicines cure cancer, inflammation, and other illnesses using the leaves of Psidium guajava L. (Myrtaceae). The hypoglycemic, antibacterial, anti-inflammatory, antioxidant, and anticancer effects of guava are well established. Triterpenoids, sesquiterpenes, and flavonoids were investigated in this study as possible targets of guava leaf components. The goal of the current review is to raise awareness among the general public about this substance's enormous potential for both preventing and treating a number of prevalent ailments.
传统医学用番石榴的叶子来治疗癌症、炎症和其他疾病。番石榴的降糖、抗菌、抗炎、抗氧化和抗癌作用是公认的。研究了番石榴叶中三萜类、倍半萜类和类黄酮类化合物的活性。本次审查的目的是提高公众对这种物质在预防和治疗许多常见疾病方面的巨大潜力的认识。
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引用次数: 0
Pharmacological review of achyranthes aspera linn. 阿奇兰人的药学审查。
Pub Date : 2022-12-03 DOI: 10.46796/ijpc.v3i4.365
Rupesh kumar Mani, Umakanth B S, N. M., Hithesh Gowda H S, A. Babu, Syed sagheer Ahmed, Bharathi D R, R. B.
India is home to the annual herb Achyranthes aspera linn., which belongs to the Amaranthaceae family and is used medicinally. Numerous antioxidants with different pharmacological effects, including as alkaloids, terpenoids, saponins, etc., are present in this plant. Additionally, this plant has been used to isolate numerous chemical components using a variety of methods. The treatment of a wide range of human illnesses is made possible by all chemical components and pharmacological qualities. The pharmacological, phytochemical and ethnobotanical uses of Achyranthes aspera are fully discussed in this paper. The details provided here regarding A. aspera may be useful to researchers conducting additional research.
印度是一年生草本植物牛膝草(Achyranthes aspera linn)的故乡。它属于苋科,是药用的。这种植物中含有多种具有不同药理作用的抗氧化剂,包括生物碱、萜类、皂苷等。此外,这种植物已被用来分离许多化学成分使用各种方法。各种各样的人类疾病的治疗是由所有的化学成分和药理学性质。本文对牛膝的药理、植物化学和民族植物学用途进行了全面论述。这里提供的关于曲霉的细节可能对进行其他研究的研究人员有用。
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引用次数: 0
Plants used in tribal medicine due to culture and tradition factors 由于文化和传统因素,在部落医药中使用的植物
Pub Date : 2022-11-26 DOI: 10.46796/ijpc.v3i4.361
Radha S
Indian folk medicine is an age old system practiced by primitive people, particularly; the tribal’s residing in remote villages and forests. The knowledge gained over the years - through trial and error methods - about the medicinal uses of local flora are transmitted from one generation to another. It is an outcome of bold experimentation and useful observations made over several hundreds of years and are in fact considered as mother of all other traditional systems of medicine. This system is losing ground with time and getting influenced by modern medicinal practices. The depletion of the forest resources and lack of proper recognition to the traditional healers, is posing threat of losing the valuable age old knowledge. Traditional indigenous medicinal practice is a repository of knowledge that needs to dovetail with the innovations and practices of modern medicine for betterment of mankind.The “Study of Traditional medicinal practice among the Tribals of Andhra Pradesh and Telangana” was primarily undertaken to document and recognize the sustainable indigenous medicinal knowledge and practices of the tribals located in the Eastern Ghats of Srikakulam and Visakhapatnam in Andhra Pradesh and in Adilabad in Telangana. It is a qualitative and quantitative study, where data were gathered through interviews, direct observation, focus group discussions and questionnaires, and analyzed. The study brings to light that, how unique and innovative they were and how, over a period of time, the practices and knowledge is losing its ground and its impact on mankind, and environment, It has also raised pertinent questions on sustainability and the increased vulnerability of traditional healers.
印度民间医学是一种古老的制度,特别是原始人;这个部落居住在偏远的村庄和森林里。多年来通过试验和错误方法获得的关于当地植物药用的知识代代相传。它是数百年来大胆实验和有益观察的结果,实际上被认为是所有其他传统医学体系之母。随着时间的推移,这一体系正逐渐失势,并受到现代医学实践的影响。森林资源的枯竭和对传统治疗师缺乏适当认识,正威胁着失去宝贵的古老知识。传统的土著医学做法是一个知识宝库,需要与现代医学的创新和实践相结合,以改善人类。“安得拉邦和特伦甘纳邦部落传统医学实践研究”主要是为了记录和认可安得拉邦斯里卡库拉姆和维沙卡帕特南的东高止人部落以及特伦甘纳邦阿迪拉巴德的土著医学知识和实践。这是一项定性和定量研究,通过访谈,直接观察,焦点小组讨论和问卷调查收集数据,并进行分析。这项研究揭示了他们是多么独特和创新,以及在一段时间内,这些实践和知识是如何失去其基础及其对人类和环境的影响的。它还提出了有关可持续性和传统治疗师日益脆弱的相关问题。
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引用次数: 0
A contemporary review on pharmacognosy and pharmacological activities of mentha arvensis. 薄荷的生药学和药理活性研究进展。
Pub Date : 2022-07-30 DOI: 10.46796/ijpc.v3i3.344
Hamsa. C.B, Aishwarya B, Roopa D, R. M, B. Dr, Agheer Ahmed Syed
Mentha arvensis belongs to the family Lamiaceae, it is also called Japanese menthol mint. This plant is endemic to Japan, as well as other parts of Europe, Central Asia, and Eastern Siberia. The pharmacological activity of M. arvensis is anti-microbial, anti-ulcer, radioprotective, cardiovascular, antioxidant activity, anti-allergic activity, and antidiabetic activity, cytotoxic properties, which are consistent with the plant's ethnopharmacological applications. Menthol is obtained from plant leaves of M. arvensis. Natural menthol is widely used in foods, confections, and cigarettes because of the cooling impact it has on the skin and mucous membranes of various body organs. Traditionally it is used as a contraceptive, carminative, antispasmodic, anti-peptic ulcer healing agent, and as a treatment for cough and cold. M. arvensis also used to treat liver and spleen illnesses, as well as asthma and jaundice. The leaf extract is used to treat rheumatoid arthritis, treat infections, and prevent mosquitoes.
薄荷属薄荷科,又称日本薄荷。这种植物是日本以及欧洲其他地区、中亚和东西伯利亚的特有植物。M. arvensis的药理活性是抗微生物、抗溃疡、抗辐射、心血管、抗氧化、抗过敏、抗糖尿病和细胞毒性,这与该植物的民族药理学应用是一致的。薄荷醇是从M. arvensis植物的叶子中提取的。天然薄荷醇被广泛应用于食品、糖果和香烟中,因为它对人体各器官的皮肤和粘膜具有冷却作用。传统上,它被用作避孕、驱风、解痉、抗消化性溃疡愈合剂,并用于治疗咳嗽和感冒。黄芪也用于治疗肝脏和脾脏疾病,以及哮喘和黄疸。叶提取物用于治疗类风湿性关节炎,治疗感染,并防止蚊子。
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引用次数: 0
A detailed study of phytochemical and invitro anticancer study on euphorbia heterophylla .l 大戟植物化学及体外抗癌研究的详细研究
Pub Date : 2022-06-15 DOI: 10.46796/ijpc.v3i2.326
S. M, Beebi Hazara M, D. P, S. M, A. S, S. Y
Health is the main issue of today’s life. Most the diseases are due to improper life style, Taking improper functional foods and by depend on fast, junk foods. Due to these foods, oxidation takes place and oxidation causes lysis of cell and it causes cancer Plants such as Euphorbia heterophylla are commonly found in our surroundings. They are also used for the management of different human diseases. The anticancer activities of leaves from these plants were investigated using aqueous extracts. The extracts are subjected to phytochemical analysis. The invitro methods were used for significant cytotoxicity on Human ovarian cancer cell lines, viz., Pa-1 cells with the IC50 concentrations (The Concentration of the Compound have the capacity to kill 50% of Viable Cells) at 57.08ug/ml respectively after the incubation period of 24hrs. The MTT assay is a colorimetric assay used for the determination of cell proliferation and cytotoxicity, based on reduction of the yellow coloured water soluble tetrazolium dye MTT to formazan crystals. The obtained results suggesting us that the EHE may have effective anticancer potential against the Human ovarian cancer (Pa-1) cells due to its low IC50 value.
健康是当今生活的主要问题。大多数疾病是由于不适当的生活方式,食用不适当的功能食品和依赖快餐,垃圾食品。由于这些食物,氧化发生,氧化导致细胞裂解,并导致癌症,像大戟这样的植物在我们的环境中很常见。它们也被用于管理不同的人类疾病。采用水提液对这些植物叶片的抗癌活性进行了研究。这些提取物要经过植物化学分析。体外方法对人卵巢癌细胞系Pa-1细胞具有明显的细胞毒性,其IC50浓度为57.08ug/ml(该化合物的浓度具有杀死50%活细胞的能力),孵育24h后。MTT法是一种用于测定细胞增殖和细胞毒性的比色法,其原理是将黄色水溶性四氮唑染料MTT还原为甲醛晶体。结果提示EHE具有较低的IC50值,可能对人卵巢癌(Pa-1)细胞具有较强的抗癌作用。
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引用次数: 0
Bio-adsorption of copper (II) from synthetic wastewater using Vaucheria sp. Dead biomass 利用Vaucheria sp.死生物质吸附合成废水中的铜(II)
Pub Date : 2022-06-13 DOI: 10.46796/ijpc.v3i2.320
A. Rastogi
The ability of the yellow-green alga Vaucheria sp. to remove Copper (II) from synthetic wastewater through the adsorption process was investigated in this communication. The pH of the solution, the adsorbent dose, the initial concentration of Cu (II) ions, the contact period, and the temperature are all factors that influenced Cu (II) sorption. The adsorption capacity at 5 pH, 80 minutes of contact time, and 318 K was calculated using the Langmuir adsorption model. By comparing the coefficient correlation (R2) values, both the Langmuir and Freundlich equations were found to fit the equilibrium data. The parameters (ΔGo, ΔHo, and ΔSo) were examined during thermodynamic tests at three distinct temperatures: 298, 308, and 318 K, suggesting that the process was sustained, spontaneous, and endothermic. Pseudo-second-order kinetic models accurately described adsorption kinetics when compared to pseudo-first-order kinetic models. Finally, the current research revealed that the bio-adsorption technique utilizing Vaucheria sp. alga could be an inexpensive and effective way to adsorb and remove Cu (II) metal ions from synthetic waste waters.
研究了黄绿藻Vaucheria sp.通过吸附过程去除合成废水中铜(II)的能力。溶液的pH、吸附剂的剂量、Cu (II)离子的初始浓度、接触时间和温度都是影响Cu (II)吸附的因素。采用Langmuir吸附模型计算了在5 pH、80 min接触时间、318 K条件下的吸附量。通过比较相关系数(R2)值,发现Langmuir方程和Freundlich方程都符合平衡数据。参数(ΔGo, ΔHo和ΔSo)在三个不同的温度下进行热力学测试:298,308和318 K,表明该过程是持续的,自发的和吸热的。与伪一级动力学模型相比,伪二级动力学模型更准确地描述了吸附动力学。最后,本研究表明,利用沃氏菌藻类进行生物吸附技术是一种廉价、有效的吸附和去除合成废水中Cu (II)金属离子的方法。
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引用次数: 0
Aerva lanata: A Comprehensive Profile in the Pharmaceutical and food Industries Aerva lanata:制药和食品工业的综合概况
Pub Date : 2022-05-31 DOI: 10.46796/ijpc.v3i2.321
Gaurav M Prajapati, R. S. Kadam, Devang R. Ghuge
Aerva lanata (L.) Juss Ex. Schult is also known as Mount knotgrass and called Polphala or Gorakha Ganga belonging to the family of Amaranthaceae. There are medicinal properties present in each part of the plant including stem, leaves, flowers, etc. This article wishes to achieve ways in order to augment the application of this plant in varied sectors and stretch the therapeutic potential of Aerva lanata species pharmaceutically, in the cosmeceutical industry, agriculturally, and the food industry. Aerva lanata and all its manufactured-products are widely used as a substantial herbal medicine system. Although they are used traditionally by a huge number of people in local areas, its potential capability of therapeutic existence is still undiscovered. This organized review is an extensive compilation of all the detailed data on phytochemistry, wide ethnopharmacological uses, medicinal characteristics and commercially applicable formula of Aerva lanata in different sectors, with the potential of antimicrobial, antiparasitic, diuretic, and anti-urolithiasis, acute renal failure, anti-asthmatic, anti-infertility, anti-hyperglycemic and anti-diabetic, hypolipidemic, hepatoprotective, immunomodulatory, anti-tumor, anti-diarrheal, anti-urolithiatic, nephroprotective, anti-ulcer, anti-HIV, anti-microbial, antioxidant etc. It will also pave a path for forthcoming research for the development of herbaceous drugs and other products to be used in agricultural and the food industry, largely contributing to the development of both these tracts.
水芹(L.)Juss Ex. Schult也被称为山红叶草,被称为Polphala或Gorakha Ganga,属于苋科。这种植物的每一部分都有药用价值,包括茎、叶、花等。本文旨在扩大该植物在各个领域的应用,并在医药、药妆工业、农业和食品工业中发挥其治疗潜力。Aerva lanata及其所有生产的产品作为一种实质性的草药系统被广泛使用。虽然它们在当地被大量的人传统地使用,但其潜在的治疗能力仍未被发现。本综述是一篇有组织的文献综述,广泛收集了黄貂鱼在不同领域的植物化学、广泛的民族药理学用途、药用特性和商业应用配方等方面的详细资料,具有抗菌、抗寄生虫、利尿、抗尿石症、急性肾衰竭、抗哮喘、抗不孕、降糖降糖、降血脂、保肝、免疫调节、抗肿瘤、抗腹泻、抗尿石、肾保护、抗溃疡、抗hiv、抗微生物、抗氧化等。它还将为即将进行的研究铺平道路,以便开发用于农业和食品工业的草本药物和其他产品,从而在很大程度上促进这两个领域的发展。
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引用次数: 0
A current study on pharmacology and phytochemistry of biophytum sensitivum 敏生菌的药理学和植物化学研究进展
Pub Date : 2022-05-22 DOI: 10.46796/ijpc.v3i2.319
Roopa D, Bharathi D R, Rupesh kumar Mani, Gurusidda, S. V
Biophytum sensitivum (L.) DC, a highly valuable medicinal herb from the Daspushpam category of Ayurvedic essential plants in the Oxalidaceae family. It is also called as, little tree plant, life plant and sensitive plant growing in Africa, South Asia and Madagascar's tropical region. It has an intriguing characteristic that is similar to that of the touch-me-not plant. This article describes the synonyms, biological source, phytoconstituents and various pharmacological activities of   Biophytum sensitivum (L.) DC, which include Anti-inflammatory, Anti diabetic, Anti urolithiatic, Antibacterial, Immunomodulatory and anti tumor activity, Nephroprotective activity, Antifertility, Radioprotective, Hypocholesterolemic effect, Wound healing, Anti-fungal activity, Antihypertensive, Analgesic activity, Antipyretic activity, Chemoprotective activity, Anti-fungal activity ,Anti angiogenic activity, Anti-metastatic activity, Larvicidal activity and Diuretic activity.
敏生植物(L.)一种非常有价值的草药,来自阿育吠陀草科必需植物的Daspushpam类别。又称小乔木、生命植物和敏感植物,生长在非洲、南亚和马达加斯加热带地区。它有一个有趣的特征,类似于不碰我的植物。本文介绍了敏生植物(Biophytum sensitivum, L.)的近义词、生物来源、植物成分及各种药理活性。DC,包括抗炎、抗糖尿病、抗尿石、抗菌、免疫调节和抗肿瘤活性、肾保护活性、抗生育、抗辐射、降胆固醇作用、伤口愈合、抗真菌活性、降压、镇痛活性、解热活性、化学保护活性、抗真菌活性、抗血管生成活性、抗转移活性、杀幼虫活性和利尿活性。
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引用次数: 0
期刊
International Journal of Pharmacognosy and Chemistry
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