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International Journal of Research in Pharmaceutical Sciences最新文献

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Test 测试
Pub Date : 2023-02-04 DOI: 10.26452/ijrps.v14i1.4222
KP Arun
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引用次数: 0
Test 测试
Pub Date : 2023-02-01 DOI: 10.26452/ijrps.v14i1.4208
Neelam Injeti
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{"title":"Test","authors":"Neelam Injeti","doi":"10.26452/ijrps.v14i1.4208","DOIUrl":"https://doi.org/10.26452/ijrps.v14i1.4208","url":null,"abstract":"check","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136171988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Test 测试
Pub Date : 2023-01-09 DOI: 10.26452/ijrps.v14i1.4178
Anandaraj
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引用次数: 0
Test 测试
Pub Date : 2023-01-05 DOI: 10.26452/ijrps.v14i1.4175
Neelam Injeti
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引用次数: 0
Test-anandh Test-anandh
Pub Date : 2023-01-05 DOI: 10.26452/ijrps.v14i1.4176
Neelam Injeti
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引用次数: 0
Test 测试
Pub Date : 2023-01-05 DOI: 10.26452/ijrps.v14i1.4174
Neelam Injeti
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引用次数: 0
Test-anandh Test-anandh
Pub Date : 2023-01-05 DOI: 10.26452/ijrps.v14i1.4177
Neelam Injeti
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引用次数: 0
Comparison of Fixation and Uptake of Split Skin Graft Using Autologous Platelet Rich Plasma with Conventional Method for Ulcer 自体富血小板血浆与常规植皮法治疗溃疡的固定与吸收比较
Pub Date : 2022-12-29 DOI: 10.26452/ijrps.v13i4.4149
Raguram V., Jai Vinod Kumar R., Velineni Bharath
Platelet Rich Plasma contains a major Growth factor and has adhesive and healing properties. PRP promotes angiogenesis, collagen synthesis, and wound healing. The main aim of this study is to compare the efficacy of SSG fixation using autologous platelet-rich plasma with the conventional method like suturing. In this study, patients who were admitted with a diagnosis of ”ulcer” in the General Surgery department in SRM medical college hospital and research centre were included and would be taken as subjects for this study. It is a randomized, controlled study with a sample size of 60. Thirty people were put in the autologous PRP group, and another 30 people were put in the suture group. Instant graft uptake of SSG to the ulcer was statistically significant in the PRP group. The seroma formation, the number of dressings and the period of hospital stay were comparatively increased in the suture group than in the PRP. The usage of PRP is secure and efficient in healing ulcer. It has been discovered to be very advantageous in many ways for both the patient and the surgeon. Based on what we found, we recommend using autologous PRP on wounds before resurfacing to help them heal better and faster than suturing.
富血小板血浆含有一种主要的生长因子,具有粘附和愈合特性。PRP促进血管生成、胶原合成和伤口愈合。本研究的主要目的是比较自体富血小板血浆与缝合等常规方法固定SSG的疗效。本研究纳入SRM医学院附属医院及研究中心普外科以“溃疡”诊断入院的患者作为本研究的研究对象。这是一项随机对照研究,样本量为60人。自体PRP组30人,缝合组30人。在PRP组,即刻移植到溃疡的SSG吸收具有统计学意义。缝合组血肿形成、敷料次数、住院时间均较PRP组明显增加。应用PRP治疗溃疡安全、有效。人们发现它在许多方面对病人和外科医生都是非常有利的。根据我们的发现,我们建议在伤口表面重新铺设之前使用自体PRP,以帮助伤口愈合得更好更快。
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引用次数: 0
A Randomised Control Trial in Comparison of Polypropylene Mesh Versus Polyester Mesh in Open Inguinal Hernia Repair 聚丙烯网片与聚酯网片在开放式腹股沟疝修补中的比较的随机对照试验
Pub Date : 2022-12-16 DOI: 10.26452/ijrps.v13i4.3959
K. Arun
a
一个
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引用次数: 0
Development and Validation of Simple UV Spectrophotometric Method for the Determination of Pretomanid 紫外分光光度法测定Pretomanid的建立与验证
Pub Date : 2022-12-14 DOI: 10.26452/ijrps.v13i4.3939
Vaishali Pardeshi, Tushar Lokhande, Ashwini Shelke
In order to treat multidrug resistant TB, pretomanid, a nitroimidazooxazine antimycobacterial agent, is used with other antituberculosis medications. There is no technique for its analysis that uses spectroscopy, HPLC or HPTLC. Since a UV spectrophotometric approach for Pretomanid analysis must be developed. Utilizing a Shimadzu UV-2600, a quick, accurate, straightforward, and affordable UV spectrophotometric approach has been devised to determine Pretomanid. Solvent made of methanol to assess the bulk Pretomanid concentration. The detection process was placed at a wavelength of 321 nm. The parameters linearity, accuracy, precision, ruggedness, and robustness were taken into consideration during method validation in accordance with ICH Q2R1 criteria, as well as LOD and LOQ. It demonstrated linearity in the 10– 30(g/mL) range at a predetermined max of 321 nm, and had a strong correlation coefficient (R2-0.997) and outstanding mean recovery (99.00–100.07%). In terms of intraday and interday precision, Pretomanid’s% RSD was discovered to be 0.6366 and 0.666, respectively. Pretomanid identification using this approach was effective. The method’s  linearity,  accuracy,  repeatability, and reproducibility were statistically and empirically verified. The out- comes demonstrated the method’s applicability for both routine examinations of protomanid bulks and industrial formulations. The suggested UV-Vis Spectrophotometric approach was verified in accordance with ICH requirements and found to be simple, accurate, precise and quick for the determination of Pretomanid.
为了治疗耐多药结核病,与其他抗结核药物一起使用了一种硝基咪唑嗪类抗细菌剂pretomanid。目前还没有光谱、高效液相色谱或HPTLC分析技术。由于紫外分光光度法分析Pretomanid必须发展。利用岛津UV-2600,设计了一种快速、准确、直接、经济的紫外分光光度法来测定Pretomanid。用甲醇配制的溶剂来评估Pretomanid的体积浓度。检测过程的波长为321 nm。根据ICH Q2R1标准以及定量限和定量限进行方法验证,考虑参数的线性、准确度、精密度、坚固性和稳健性。在10 ~ 30(g/mL)范围内呈良好的线性关系,在321 nm范围内具有较强的相关系数(r2 ~ 0.997),平均回收率为99.00 ~ 100.07%。在日内和日间精度方面,Pretomanid的% RSD分别为0.6366和0.666。用这种方法鉴定Pretomanid是有效的。方法的线性度、准确度、重复性和再现性经统计学和经验验证。结果表明,该方法适用于原动物体和工业制剂的常规检查。经验证,该方法简便、准确、精密度高、快速,符合ICH要求。
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引用次数: 0
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International Journal of Research in Pharmaceutical Sciences
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