Pub Date : 2023-11-20DOI: 10.26452/ijrps.v14i4.4479
Selvi G
Autoimmunity is a misguided immune response that occurs when the immune system becomes disorganized and attacks the body. While autoimmunity is prevalent to some extent in most of us, it is often harmless. This immune response can sometimes cause a wide range of diseases known as autoimmune diseases. Autoimmune diseases start when there is a development from submissive autoimmunity to pathogenic autoimmunity. This progression is influenced by both genetic and environmental factors and mostly remains dormant for a period. A sudden recurrence of emergencies occurs with few options for survival. When T or B-cells or both get stimulated in the absence of infection, it results in a state where the immune system is unable to distinguish between self or non-self. This results in the efflux of immune cells leading to the destruction of self-molecules. The exact process governing this event is still inconclusive, but the research done so far predicts that genetics, habitat, and infections must be major causes of abnormal activation of the autoimmune reaction.
自身免疫是一种被误导的免疫反应，当免疫系统变得混乱并攻击身体时就会发生。虽然自身免疫在我们大多数人身上都普遍存在，但它通常是无害的。这种免疫反应有时会导致多种疾病，即所谓的自身免疫性疾病。自身免疫性疾病始于从顺从性自身免疫发展到致病性自身免疫。这种发展受遗传和环境因素的影响，大多会休眠一段时间。在几乎没有生存选择的情况下，紧急情况突然复发。当 T 细胞或 B 细胞或两者在没有感染的情况下受到刺激时，就会导致免疫系统无法区分自身或非自身。这导致免疫细胞外流，从而破坏自身分子。这一事件的确切过程尚无定论，但迄今为止的研究预测，遗传、生境和感染一定是导致自身免疫反应异常激活的主要原因。
{"title":"An insight into the little-known, menacing facts of autoimmune disorder","authors":"Selvi G","doi":"10.26452/ijrps.v14i4.4479","DOIUrl":"https://doi.org/10.26452/ijrps.v14i4.4479","url":null,"abstract":"Autoimmunity is a misguided immune response that occurs when the immune system becomes disorganized and attacks the body. While autoimmunity is prevalent to some extent in most of us, it is often harmless. This immune response can sometimes cause a wide range of diseases known as autoimmune diseases. Autoimmune diseases start when there is a development from submissive autoimmunity to pathogenic autoimmunity. This progression is influenced by both genetic and environmental factors and mostly remains dormant for a period. A sudden recurrence of emergencies occurs with few options for survival. When T or B-cells or both get stimulated in the absence of infection, it results in a state where the immune system is unable to distinguish between self or non-self. This results in the efflux of immune cells leading to the destruction of self-molecules. The exact process governing this event is still inconclusive, but the research done so far predicts that genetics, habitat, and infections must be major causes of abnormal activation of the autoimmune reaction.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"24 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139256584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-21DOI: 10.26452/ijrps.v9i4.4454
None Deepak Nallaswamy, None Vishnu Priya V, None Gayathri R
Flipped classroom alters the conventional learning environment and brings out innovation and creativity in the teaching-learning process. The flipped classroom has begun to enhance the way the students receive information from their mentors. Audiovisual aids create a virtual classroom at home. Classroom time is more focused on student-centred learning activities, such as concept mapping, process-oriented guided inquiry learning, peer-led team-based learning, game-based learning, critical pedagogy. This improves better understanding of the subject, develop cognitive skills and enhance the conceptual learning of the students. Academic performance of the students exposed to flipped videos integrated with iBooks was evaluated and com- pared with the traditional learning environment.
{"title":"Flipped Classroom – A novel breakthrough in learning","authors":"None Deepak Nallaswamy, None Vishnu Priya V, None Gayathri R","doi":"10.26452/ijrps.v9i4.4454","DOIUrl":"https://doi.org/10.26452/ijrps.v9i4.4454","url":null,"abstract":"Flipped classroom alters the conventional learning environment and brings out innovation and creativity in the teaching-learning process. The flipped classroom has begun to enhance the way the students receive information from their mentors. Audiovisual aids create a virtual classroom at home. Classroom time is more focused on student-centred learning activities, such as concept mapping, process-oriented guided inquiry learning, peer-led team-based learning, game-based learning, critical pedagogy. This improves better understanding of the subject, develop cognitive skills and enhance the conceptual learning of the students. Academic performance of the students exposed to flipped videos integrated with iBooks was evaluated and com- pared with the traditional learning environment.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"48 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135511899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-17DOI: 10.26452/ijrps.v14i4.4452
Hana J. Al Khabbaz
Adverse drug reaction (ADR) reporting is an important aspect of pharmacovigilance (PV) in ensuring drug safety during the post-marketing surveillance phase. Currently, the National Pharmacovigilance Center (NPC) established by the Saudi Food and Drug Authority (SFDA) is the regulatory authority receiving ADR reports in Saudi Arabia. Spontaneous ADR reports from healthcare professionals and the public are received by the NPC through an electronic platform known as the Saudi Vigilance System. Signal analysis of the received ADR reports aids the decision-making initiatives related to the reported drugs. Stakeholders’ contribution to ADR reporting, and implementation of effective electronic platforms are important factors affecting the national PV performance. The concept of stakeholders reporting on ADR is relatively new in Saudi Arabia, especially to the public. In this narrative review the national studies describing the stakeholders’ knowledge, perception and barriers toward ADR reporting, and the incidence of ADR reporting by healthcare institutions in Saudi Arabia were evaluated. The findings indicate that more efforts are needed by the SFDA to educate stakeholders about the importance of ADR reporting. The study recommends ADR electronic systems integration between the SFDA and healthcare institutions to improve the frequency and quality of ADR reports, and regular feedback on decisions made about ADR reports should be provided by the SFDA to stakeholders to improve their awareness of the importance of ADR reporting and enhance their contribution to PV and ADR reporting process.
{"title":"Pharmacovigilance in Saudi Arabia: A Narrative Review on Adverse Drug Reaction Reporting","authors":"Hana J. Al Khabbaz","doi":"10.26452/ijrps.v14i4.4452","DOIUrl":"https://doi.org/10.26452/ijrps.v14i4.4452","url":null,"abstract":"Adverse drug reaction (ADR) reporting is an important aspect of pharmacovigilance (PV) in ensuring drug safety during the post-marketing surveillance phase. Currently, the National Pharmacovigilance Center (NPC) established by the Saudi Food and Drug Authority (SFDA) is the regulatory authority receiving ADR reports in Saudi Arabia. Spontaneous ADR reports from healthcare professionals and the public are received by the NPC through an electronic platform known as the Saudi Vigilance System. Signal analysis of the received ADR reports aids the decision-making initiatives related to the reported drugs. Stakeholders’ contribution to ADR reporting, and implementation of effective electronic platforms are important factors affecting the national PV performance. The concept of stakeholders reporting on ADR is relatively new in Saudi Arabia, especially to the public. In this narrative review the national studies describing the stakeholders’ knowledge, perception and barriers toward ADR reporting, and the incidence of ADR reporting by healthcare institutions in Saudi Arabia were evaluated. The findings indicate that more efforts are needed by the SFDA to educate stakeholders about the importance of ADR reporting. The study recommends ADR electronic systems integration between the SFDA and healthcare institutions to improve the frequency and quality of ADR reports, and regular feedback on decisions made about ADR reports should be provided by the SFDA to stakeholders to improve their awareness of the importance of ADR reporting and enhance their contribution to PV and ADR reporting process.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136032475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-06DOI: 10.26452/ijrps.v14i4.4448
Noor Mohamed M, Parameswari M, Pavithra B, Naveen Kumar S, Nirmal Kumar P, Jothirani P
Raphinus sativus extract was prepared by Soxhlet extraction method using various solvents such as ethyl acetate (polar solvent) water and ethanol (nonpolar). The chemical test was performed to identify the presence of flavonoid content. Among them ethyl acetate extract shows a high flavonoid content.So it was used for further studies. By using the in vitro agar well diffusion method, antibacterial activity was measured in all extracts. 2 strains of bacteria were chosen for testing, including gram-positive (Staphylococcus aureus, ATCC25923) and gram-negative (E. coli, ATCC25922) bacteria. The diameter of the zone of inhibition were measured and compared to the amoxicillin reference standard.Compared to gram-positive bacteria, the extract exhibits higher potential activity against gram-negative bacteria. Concentration directly relates to how much action is taken.
{"title":"The Antibacterial Activity of Various Solvent Extracts of Leaves of Raphunus sativus","authors":"Noor Mohamed M, Parameswari M, Pavithra B, Naveen Kumar S, Nirmal Kumar P, Jothirani P","doi":"10.26452/ijrps.v14i4.4448","DOIUrl":"https://doi.org/10.26452/ijrps.v14i4.4448","url":null,"abstract":"Raphinus sativus extract was prepared by Soxhlet extraction method using various solvents such as ethyl acetate (polar solvent) water and ethanol (nonpolar). The chemical test was performed to identify the presence of flavonoid content. Among them ethyl acetate extract shows a high flavonoid content.So it was used for further studies. By using the in vitro agar well diffusion method, antibacterial activity was measured in all extracts. 2 strains of bacteria were chosen for testing, including gram-positive (Staphylococcus aureus, ATCC25923) and gram-negative (E. coli, ATCC25922) bacteria. The diameter of the zone of inhibition were measured and compared to the amoxicillin reference standard.Compared to gram-positive bacteria, the extract exhibits higher potential activity against gram-negative bacteria. Concentration directly relates to how much action is taken.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135350937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-19DOI: 10.26452/ijrps.v14i3.4310
M. C., Hasna P, Nayana Km, Jassim M, Aparna Ks
Stroke comprises of a broad term encompassing many disorders of the blood vessels of the central nervous system that may result from either inadequate blood flow to the brain with subsequent infarction of the involved portion of the CNS or haemorrhages into the parenchyma or subarachnoid space of the CNS causing neurologic dysfunction. Stroke is one of the major cause of mortality worldwide. The objective of the study was to assess the drug utilization pattern (DUP) and to evaluate the impact of counseling on medication adherence for stroke patient admitted in the hospital. Dual antiplatelet therapy (69.4%) was mostly given over monotherapy (28.2%). CCB (28.2%) was the most commonly prescribed antihypertensive drug class and amlodipine (77.1%) was the major CCB given in this study. 96.5 prescriptions comply AHA/ASA guidelines. Unintentional reasons for nonadherence were been reported more frequently than intentional reasons prior to the counseling. The commonest reported unintentional reasons were Forgetfulness (96.0%), Confusion (80.0%) and intentional reasons are carelessness (92%), avoiding dosing schedule (78%). Medication adherence before and after counseling was compared and was found to be improved with a statistically significant (p
{"title":"Drug Utilization Pattern and Role of Clinical Pharmacist in Medication Adherence of Stroke Patients in a Tertiary Care Hospital, South India: A Prospective Observational Study","authors":"M. C., Hasna P, Nayana Km, Jassim M, Aparna Ks","doi":"10.26452/ijrps.v14i3.4310","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4310","url":null,"abstract":"Stroke comprises of a broad term encompassing many disorders of the blood vessels of the central nervous system that may result from either inadequate blood flow to the brain with subsequent infarction of the involved portion of the CNS or haemorrhages into the parenchyma or subarachnoid space of the CNS causing neurologic dysfunction. Stroke is one of the major cause of mortality worldwide. The objective of the study was to assess the drug utilization pattern (DUP) and to evaluate the impact of counseling on medication adherence for stroke patient admitted in the hospital. Dual antiplatelet therapy (69.4%) was mostly given over monotherapy (28.2%). CCB (28.2%) was the most commonly prescribed antihypertensive drug class and amlodipine (77.1%) was the major CCB given in this study. 96.5 prescriptions comply AHA/ASA guidelines. Unintentional reasons for nonadherence were been reported more frequently than intentional reasons prior to the counseling. The commonest reported unintentional reasons were Forgetfulness (96.0%), Confusion (80.0%) and intentional reasons are carelessness (92%), avoiding dosing schedule (78%). Medication adherence before and after counseling was compared and was found to be improved with a statistically significant (p","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79302939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-16DOI: 10.26452/ijrps.v14i3.4308
Hemamalini K, Sadanandam Palle, Kanakam Vijayabhaskar, Supraja U
Liver injury is a common disorder where natural remedies are practiced from ancient time from plant source which shows alternative treatment in a safe manner. The Hepatoprotective activity of methanolic extract of Prosopis juiliflora bark part was taken for evaluation in screening. The model chosen for the study is carbon tetrachloride (0.1ml/kg) and the standard drug silymarin of 20mg/kg was used for the study for 21 days. The hepatoprotective effect of the methanolic extract against the carbon tetrachloride-induced hepatotoxicity in wistar rats has been demonstrated by the substantial and severe reduction of enzymes in the serum.
{"title":"Phytochemical and Hepatoprotective Activity of Prosopis juliflora Barks on Different Models","authors":"Hemamalini K, Sadanandam Palle, Kanakam Vijayabhaskar, Supraja U","doi":"10.26452/ijrps.v14i3.4308","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4308","url":null,"abstract":"Liver injury is a common disorder where natural remedies are practiced from ancient time from plant source which shows alternative treatment in a safe manner. The Hepatoprotective activity of methanolic extract of Prosopis juiliflora bark part was taken for evaluation in screening. The model chosen for the study is carbon tetrachloride (0.1ml/kg) and the standard drug silymarin of 20mg/kg was used for the study for 21 days. The hepatoprotective effect of the methanolic extract against the carbon tetrachloride-induced hepatotoxicity in wistar rats has been demonstrated by the substantial and severe reduction of enzymes in the serum.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84886566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-11DOI: 10.26452/ijrps.v14i3.4306
Akighir J, Yakubu O E, Imo C, Ojogbane E, Owuna R I, Jato J A
In order to assess the total antioxidant capacity (TAC), total polyphenol content (TPC), and total flavonoid content (TFC) in ethanol fruit extract, as well as to ascertain the relationship between the antioxidant effects and phytochemical levels, this study looked at all three variables. 11 groups of 10 rats each were formed out of the experimental animals. All experimental subjects received a single intraperitoneal injection of aluminium chloride, 4.2 mg/kg body weight. Groups 4 and 5 received n-hexane fraction at 10 and 20 mg/kg b. w., respectively, whereas the other groups received various fractions and crude extracts of R. hookeri. Ethyl acetate fraction was given to groups 6 and 7 at doses of 10 and 20 mg/kg b. w. Aqueous fractions at 10 and 20 mg/kg b. w. were given to groups 8 and 9. While groups 10 and 11 got ethanolic crude extract daily for 21 days at doses of 200 mg/kg b. w. and 400 mg/kg b. w., respectively. All groups that were given AlCl3 - induced TBARS showed a significant (P 0.05) increase in vivo antioxidant activity. However, in the liver, kidney, and testes of all treatment groups, superoxide dismutase (SOD) and catalase (CAT) activity considerably increased (P 0.05). This suggests that a significant portion of the antioxidant activity displayed by the ethanolic fruit extract of R. hookeri is due to flavonoids.
为了评估乙醇水果提取物的总抗氧化能力(TAC)、总多酚含量(TPC)和总黄酮含量(TFC)，并确定抗氧化作用与植物化学水平之间的关系，本研究考察了这三个变量。实验动物共分成11组，每组10只大鼠。所有受试者均一次性腹腔注射氯化铝，剂量为4.2 mg/kg体重。第4组和第5组分别给予10和20 mg/kg体重的正己烷部位，其余组分别给予黄颡鱼不同部位和粗提物。第6组和第7组分别以10和20 mg/kg体重给予乙酸乙酯馏分，第8组和第9组分别以10和20 mg/kg体重给予水馏分。第10组和第11组分别以200 mg/kg b. w和400 mg/kg b. w的剂量给予乙醇粗提物，连续21 d。所有给予AlCl3诱导的TBARS组的体内抗氧化活性均显著提高(p0.05)。各处理组肝脏、肾脏和睾丸超氧化物歧化酶(SOD)和过氧化氢酶(CAT)活性均显著升高(P < 0.05)。由此可见，黄酮类化合物是水仙果醇提取物抗氧化活性的重要组成部分。
{"title":"Evaluation of the total antioxidant capacity, total polyphenol content, and flavonoids content in ethanolic fruit extract of Raphia hookeri and determination of the correlation between the antioxidant effects and the phytochemical contents","authors":"Akighir J, Yakubu O E, Imo C, Ojogbane E, Owuna R I, Jato J A","doi":"10.26452/ijrps.v14i3.4306","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4306","url":null,"abstract":"In order to assess the total antioxidant capacity (TAC), total polyphenol content (TPC), and total flavonoid content (TFC) in ethanol fruit extract, as well as to ascertain the relationship between the antioxidant effects and phytochemical levels, this study looked at all three variables. 11 groups of 10 rats each were formed out of the experimental animals. All experimental subjects received a single intraperitoneal injection of aluminium chloride, 4.2 mg/kg body weight. Groups 4 and 5 received n-hexane fraction at 10 and 20 mg/kg b. w., respectively, whereas the other groups received various fractions and crude extracts of R. hookeri. Ethyl acetate fraction was given to groups 6 and 7 at doses of 10 and 20 mg/kg b. w. Aqueous fractions at 10 and 20 mg/kg b. w. were given to groups 8 and 9. While groups 10 and 11 got ethanolic crude extract daily for 21 days at doses of 200 mg/kg b. w. and 400 mg/kg b. w., respectively. All groups that were given AlCl3 - induced TBARS showed a significant (P 0.05) increase in vivo antioxidant activity. However, in the liver, kidney, and testes of all treatment groups, superoxide dismutase (SOD) and catalase (CAT) activity considerably increased (P 0.05). This suggests that a significant portion of the antioxidant activity displayed by the ethanolic fruit extract of R. hookeri is due to flavonoids.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89709304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-09DOI: 10.26452/ijrps.v14i3.4302
Nupur Shukla, Monika Gupta
In the present era, with the evolution in the medical field, many parameters have gained importance in researches by the forensic experts, anthropologists in the identification of biological remains. Nowadays, complete human skeletons can be used for the identification of the biological profile of an individual. One of the emerging parameters are the foot dimensions in identification and gender determination. The study was conducted on 207 males & 200 females from Rajasthan adult population of age group 17 to 25 years. The anthropometric measurements of left foot length and breadth were measured by the digital sliding caliper. Significant Foot index was calculated, it was found that the overall left foot index for males was 37.89 and females was 38.24. This indicates that the value of left foot index is less than 38 in male but more than 38 in females. This 38 value obtained can be the deviation point in predicting the gender, by calculating the left foot index.
{"title":"Gender Determination by Using Left Foot Index in Rajasthan Adults","authors":"Nupur Shukla, Monika Gupta","doi":"10.26452/ijrps.v14i3.4302","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4302","url":null,"abstract":"In the present era, with the evolution in the medical field, many parameters have gained importance in researches by the forensic experts, anthropologists in the identification of biological remains. Nowadays, complete human skeletons can be used for the identification of the biological profile of an individual. One of the emerging parameters are the foot dimensions in identification and gender determination. The study was conducted on 207 males & 200 females from Rajasthan adult population of age group 17 to 25 years. The anthropometric measurements of left foot length and breadth were measured by the digital sliding caliper. Significant Foot index was calculated, it was found that the overall left foot index for males was 37.89 and females was 38.24. This indicates that the value of left foot index is less than 38 in male but more than 38 in females. This 38 value obtained can be the deviation point in predicting the gender, by calculating the left foot index.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78624392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-01DOI: 10.26452/ijrps.v14i3.4301
Samera S, Jayaprakash S, J. K, Bharathi P, Suryaprakash R
Weight gain has been declared as one of the top 10 global health risks by the World Health Organization (WHO). In the past few decades, obesity has increased alarmingly around the world. Most patients with type 1 diabetes possess anti-insulin antibodies before receiving insulin therapy. About 80% of patients with type 1 diabetes have circulating islet cell antibodies. Both developed and developing countries are facing a medical disaster due to obesity. The incidence of type 2 diabetes is correlated with insulin resistance. Insulin resistance does not lead to hyperglycemia in most obese individuals. The purpose of this study is to determine whether Type 2 diabetes mellitus patients are overweight or obese, and to identify risk factors for such disease. Preventing diabetes complications and reducing its prevalence. A study was conducted to determine whether obesity increases the risk of diabetes. Identify dyslipidemia in Type 2 diabetics by studying its prevalence pattern. The age range of 40 to 70 years for type 2 diabetes mellitus patients. The study also excluded participants with dyslipidemia. Various metabolic parameters were measured as well as baseline anthropometric indices (BMI, WHR). We found 25 patients in normal weight category, 3 patients in underweight category, 50 patients in overweight category, and 53 patients in obese category among the patients aged 40-50 years. Developing appropriate and controlled strategies for improving nutrition and promoting weight loss is urgently needed to mitigate Type 2 diabetes patients' increasing health challenges.
{"title":"Descriptive and Retrospective Study on the Prevalence of Overweight and Obesity among Patients with Type 2 Diabetes Mellitus","authors":"Samera S, Jayaprakash S, J. K, Bharathi P, Suryaprakash R","doi":"10.26452/ijrps.v14i3.4301","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4301","url":null,"abstract":"Weight gain has been declared as one of the top 10 global health risks by the World Health Organization (WHO). In the past few decades, obesity has increased alarmingly around the world. Most patients with type 1 diabetes possess anti-insulin antibodies before receiving insulin therapy. About 80% of patients with type 1 diabetes have circulating islet cell antibodies. Both developed and developing countries are facing a medical disaster due to obesity. The incidence of type 2 diabetes is correlated with insulin resistance. Insulin resistance does not lead to hyperglycemia in most obese individuals. The purpose of this study is to determine whether Type 2 diabetes mellitus patients are overweight or obese, and to identify risk factors for such disease. Preventing diabetes complications and reducing its prevalence. A study was conducted to determine whether obesity increases the risk of diabetes. Identify dyslipidemia in Type 2 diabetics by studying its prevalence pattern. The age range of 40 to 70 years for type 2 diabetes mellitus patients. The study also excluded participants with dyslipidemia. Various metabolic parameters were measured as well as baseline anthropometric indices (BMI, WHR). We found 25 patients in normal weight category, 3 patients in underweight category, 50 patients in overweight category, and 53 patients in obese category among the patients aged 40-50 years. Developing appropriate and controlled strategies for improving nutrition and promoting weight loss is urgently needed to mitigate Type 2 diabetes patients' increasing health challenges.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87372263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-30DOI: 10.26452/ijrps.v14i2.4286
Anandh A
check
检查
{"title":"Test","authors":"Anandh A","doi":"10.26452/ijrps.v14i2.4286","DOIUrl":"https://doi.org/10.26452/ijrps.v14i2.4286","url":null,"abstract":"check","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136155697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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