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The relationship between mother's age and newborn birth weight: a retrospective study 母亲年龄与新生儿体重关系的回顾性研究
Pub Date : 2023-10-23 DOI: 10.18203/issn.2454-2156.intjscirep20233165
Leila Sekhavat, Atiyeh Javaheri
Background: The objective of this study is to assess the impact of maternal age on neonatal birth weight. Methods: A retrospective study was conducted to evaluate the neonatal birth weight of singleton term infants born to nulliparous, non-diabetic, urban women who delivered at Shahid Sadoughi hospital in Yazd, Iran, between 2020 and 2021. Maternal age groups were defined as adolescents (≤19 years old) and adults (20-40 years old) using data from archived files. Results: A total of 963 cases were included in this study, with 217 adolescents and 746 adults. The incidence of low birth weight (LBW) (<2500 gr) was 10.6% (102 cases), and macrosomia (>4000 gr) was observed in 7.1% (68 cases) of the neonates. There was a significantly higher rate of neonatal LBW among adolescent mothers. Conclusions: Our study demonstrates that maternal age has an impact on neonatal birth weight. The incidence of LBW is increased among adolescent mothers.
背景:本研究目的是评估产妇年龄对新生儿出生体重的影响。 方法:回顾性研究了2020年至2021年期间在伊朗亚兹德Shahid Sadoughi医院分娩的无产、非糖尿病的城市妇女所生的单胎足月婴儿的新生儿出生体重。使用存档文件中的数据,将产妇年龄组定义为青少年(≤19岁)和成年人(20-40岁)。 结果:共纳入963例,其中青少年217例,成人746例。低出生体重(LBW)(2500克)发生率为10.6%(102例),巨大儿(4000克)发生率为7.1%(68例)。青少年母亲的新生儿低体重率显著高于青少年母亲。 结论:我们的研究表明,产妇年龄对新生儿出生体重有影响。少女母亲中LBW的发病率有所增加。
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引用次数: 0
Assessment of knowledge of differentiated service delivery among HIV-positive patients receiving care in a Southeastern Nigerian State 评估尼日利亚东南部一个州接受治疗的艾滋病毒阳性患者对差异化服务提供的了解
Pub Date : 2023-10-23 DOI: 10.18203/issn.2454-2156.intjscirep20233164
Azubuike A. Ekwuofu, Obinna F. Dim, Maxwell O. Adibe, Uzoma B. Okwara
Background: Since the adoption of the differentiated service delivery (DSD) as a programmatic strategy in the delivery of antiretroviral therapy (ART) in Imo state, no research has assessed the level of knowledge of DSD among HIV-positive patients receiving ART in the state, a research gap which this study aimed to fill. Methods: This was a cross sectional study carried out among the adult patients receiving ART in three DSD models and the usual care group at one tertiary and three secondary hospitals using a structured questionnaire validated by the researcher. Descriptive and inferential analyses were performed using the statistical product and service solutions (SPSS) version 24. All the analysis was performed at p≤0.05. Results: Of the 542 questionnaires retrieved, the female gender was predominant in all the groups. Up to 57.3% and 55.5% of the patients had good knowledge and perception towards differentiated care respectively. A significant difference was found in the mean perception among the groups (F (3.538)=9.309, p<0.05). While education and participation in HIV activities were found to be significant predators of knowledge of DSD, (F (10.466)=3.082, R2 of 0.062, p<0.05), only education was found to be determinant of perception. Conclusions: This study has shown that the patients had fair knowledge of the DSD in all the models examined, as well as the usual group; and this did not differ significantly across the groups. However, there is need to improve on patients' enlightenment of the initiative, especially for those in the usual care group.
背景:自Imo州将差异化服务提供(DSD)作为提供抗逆转录病毒治疗(ART)的一项规划策略以来,尚未有研究评估该州接受抗逆转录病毒治疗的hiv阳性患者对DSD的了解水平,本研究旨在填补这一研究空白。方法:这是一项横断面研究,采用经研究者验证的结构化问卷,在三家三级和三家二级医院的三个DSD模型和常规护理组接受ART治疗的成年患者中进行。使用统计产品和服务解决方案(SPSS)版本24进行描述性和推断性分析。所有分析均以p≤0.05进行。 结果:在542份问卷中,各组均以女性为主。分别有57.3%和55.5%的患者对差异化护理有良好的认识和感知。组间平均知觉差异有统计学意义(F (3.538)=9.309, p<0.05)。教育程度和艾滋病活动的参与程度是影响艾滋病知识的显著因素(F (10.466)=3.082, R2为0.062,p<0.05),只有教育程度是影响艾滋病知识的决定因素。 结论:本研究表明,与正常组相比,所有模型的患者对DSD的认识都比较公平;这在两组之间并没有显著差异。但是,对患者主动性的启蒙,特别是常规护理组的启蒙还有待提高。
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引用次数: 0
Predicting the potential worldwide distribution of Aedes aegypti under climate change scenarios 预测气候变化情景下埃及伊蚊的潜在全球分布
Pub Date : 2023-10-23 DOI: 10.18203/issn.2454-2156.intjscirep20233163
Sanad H. Ragab, Michael G. Tyshenko
Background: Climate change is one of the most important factors associated with medically important insect pests such as mosquitoes (Diptera: Culicidae). Diseases spread by mosquitoes are increasing due to changes in global temperature and weather patterns that are altering vector host ranges allowing spread into new regions. Zika, dengue fever, chikungunya and yellow fever are arboviral infections that are spread by Aedes aegypti (Culicidae). The objective of the current research is to study the potential geographic distribution habitats of Ae. aegypti in the world under current and future climate conditions. Methods: Data of Ae. aegypti was obtained from the global biodiversity information facility and used 19 bioclimatic layers (bio01-bio19) and elevation from the WorldClim database. The scenarios used are the Beijing climate center climate system model (BCC-CSM2-MR) and the institute Pierre-Simon Laplace, coupled model intercomparison project (IPSL-CM6A-LR) with two shared socio-economic pathways (SSPs) for each of the general circulation model (GCMs): SSP126 and SSP585. Results: The results revealed that altitude, temperature, seasonality (standard deviation *100) (bio4), and annual precipitation (bio12) were the most important environmental variables that affect the distribution of Ae. aegypti. Conclusions: The models showed that Africa and South America maintained very high and excellent habitat suitability for Ae. Aegypti under the current potential distribution map.
背景:气候变化是与蚊子(双翅目:库蚊科)等医学重要害虫相关的最重要因素之一。由于全球温度和天气模式的变化正在改变病媒宿主的范围,从而使疾病传播到新的地区,蚊子传播的疾病正在增加。寨卡病毒、登革热、基孔肯雅热和黄热病是由埃及伊蚊(库蚊科)传播的虫媒病毒感染。本研究的目的是研究伊蚊的潜在地理分布生境。埃及伊蚊在当前和未来气候条件下的分布。方法:采沙伊蚊;埃及伊蚊从全球生物多样性信息设施获得,并利用世界气候数据库中的19个生物气候层(bio01-bio19)和海拔。使用的情景是北京气候中心气候系统模式(BCC-CSM2-MR)和皮埃尔-西蒙·拉普拉斯研究所耦合模式比较项目(IPSL-CM6A-LR),每个环流模式(GCMs): SSP126和SSP585都有两个共享的社会经济路径(ssp)。结果:海拔高度、气温、季节(标准差*100)(bio4)和年降水量(bio12)是影响伊蚊分布的最重要环境变量。蚊。结论:模拟结果表明,非洲和南美洲对白纹伊蚊的生境适宜性非常高。埃及伊蚊在当前潜在分布图下的分布。
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引用次数: 0
COVID-19 cases prediction with negative group delays digital function 用负组延迟数字功能预测新冠肺炎病例
Pub Date : 2023-10-23 DOI: 10.18203/issn.2454-2156.intjscirep20233166
Blaise Ravelo, Mathieu Guerin, Habachi Bilal, Sylcolin Rakotonandrasana, Wenceslas Rahajandraibe
The negative group delay (NGD) is an uncommon function enabling to propagate arbitrary waveform signals with time-advance behavior. The counterintuitive NGD function was initially experimented for anticipating typically fast and short duration electronic signals in micro- and milli-second time scale. The application of NGD function to large time scale signal attracts more and more the attention of data processing engineer. This paper aims to investigate on the ability of NGD function to predict time- dependent social data with someday time-advances. As practical case of study, an innovative application of NGD function for predicting disease cases is treated. The digital circuit theory enabling to understand the low-pass (LP) NGD canonical TF and the characterization approach is established. It is shown in which condition the first order difference equation represents a LP-NGD circuit. Then, the design method of typical LP-NGD predictor as numerical circuit is introduced in function of the expected time-advance. The NGD predictor time-variation property is theoretically initiated. The NGD time-advance varied from -7 days to -1/2 days is investigated with deterministic data prediction processing from 5-months bi- exponential waveform data. The predicted data with time-advance of about -4 days was confirmed by analytical computation and simulation. The LP-NGD digital predictor feasibility is validated with monthly COVID-19 randomly arbitrary data by computed and virtually tested results. It was investigated with sensitivity analysis that the prediction performance is better when the input signal is smoothed enough. As expected, prediction result showing very good correlation with input data is demonstrated.
负群延迟(NGD)是一种不常见的函数,可以传播任意波形信号。反直觉的NGD函数最初被用于在微毫秒和毫秒的时间尺度上预测通常快速和短时间的电子信号。NGD函数在大时间尺度信号中的应用越来越受到数据处理工程师的关注。本文旨在探讨NGD函数对时变社会数据的预测能力。作为实际研究案例,探讨了NGD函数在疾病病例预测中的创新应用。建立了能够理解低通(LP) NGD规范TF的数字电路理论和表征方法。在这种情况下,一阶差分方程表示一个LP-NGD电路。然后,介绍了典型的LP-NGD预测器作为数字电路的设计方法,以期望时间提前为函数。从理论上提出了NGD预测器的时变特性。利用5个月双指数波形资料进行确定性预测处理,研究了NGD时间提前-7 ~ -1/2天的变化规律。通过解析计算和模拟验证了预测数据,预测时间提前约为-4天。通过每月COVID-19随机数据的计算和虚拟测试结果验证了LP-NGD数字预测器的可行性。通过灵敏度分析研究,当输入信号足够平滑时,预测效果较好。正如预期的那样,预测结果与输入数据具有很好的相关性。
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引用次数: 0
Leveraging electronic health records and stem cell transplants: a review 利用电子健康记录和干细胞移植:综述
Pub Date : 2023-10-23 DOI: 10.18203/issn.2454-2156.intjscirep20233167
K. S. Ravi Teja, Sai Lakshmi Gundimeda, Amulya Kolipakula, Anushree Ramprasad, Sandhya Kanti Nuzella, A. Ranganadha Reddy
Biomedical informatics is a burgeoning multidisciplinary field that seeks to optimize the utilization of biomedical data, information, and knowledge for the purposes of scientific research, inquiry, problem-solving, and decision-making, all with the overarching objective of enhancing human health and well-being. Information, informatics, and its applications are used in organ transplantations, such as stem cell transplantation programs, and in programs that directly change disorders. So, many hospitals can maintain EMRs (Electronic medical records), but few are supporting C programs. So, using informatics, we introduced software and programs to run these SCT applications in a very short period of time without any effect.
生物医学信息学是一个新兴的多学科领域,旨在优化生物医学数据、信息和知识的利用,用于科学研究、探究、解决问题和决策,所有这些都以提高人类健康和福祉为总体目标。信息、信息学及其应用被用于器官移植,如干细胞移植项目,以及直接改变疾病的项目。因此,许多医院可以维护emr(电子医疗记录),但很少支持C程序。因此,利用信息学,我们引入了软件和程序来运行这些SCT应用程序,在很短的时间内没有任何效果。
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引用次数: 0
Support vector machines in neonatal mortality detection: a comprehensive scoping review with disease-specific emphasis 支持向量机在新生儿死亡率检测:一个全面的范围审查与特定疾病的重点
Pub Date : 2023-09-27 DOI: 10.18203/issn.2454-2156.intjscirep20232912
None Zoya Aamir, None Mahrosh Kasbati, None Arusha Hasan, None Sonia Hurjkaliani, None Rayaan Imran
Neonatal mortality is a widely significant problem since diseases such as sepsis, apnea and jaundice have claimed the lives of 2.3 million neonates in 2021. As such, better tools need to be developed to reduce its rate. While traditional methods like Clinical risk index (CRIB) and Score for neonatal acute physiology (SNAP) have proven helpful in predicting neonatal mortality, there is a need for more efficient measures. One such approach is support vector machine (SVM), a supervised machine-learning algorithm that is primarily used for classification. SVM can perform both linear and non-linear classification; it conducts the latter with the assistance of the kernel trick and functions such as polynomial, gaussian, RBF and sigmoid functions. This narrative review aims to explore the potential and limitations of SVM in predicting major global causes of neonatal mortality. We searched through articles employing SVM to predict different diseases and symptoms such as sepsis, seizures, fetal heart rate, low birth weight, hypoxic-ischemic encephalopathy, apnea, jaundice and neonatal respiratory distress syndrome, and concluded that while SVM has its merits and has shown promising results in many aspects, it also has its demerits such as requiring an extensive training time to achieve higher accuracy and precision.
新生儿死亡率是一个广泛存在的重大问题,因为败血症、呼吸暂停和黄疸等疾病在2021年夺去了230万新生儿的生命。因此,需要开发更好的工具来降低其发生率。虽然临床风险指数(CRIB)和新生儿急性生理评分(SNAP)等传统方法已被证明有助于预测新生儿死亡率,但仍需要更有效的措施。其中一种方法是支持向量机(SVM),这是一种主要用于分类的监督机器学习算法。支持向量机可以进行线性和非线性分类;利用核函数技巧和多项式函数、高斯函数、RBF函数、sigmoid函数等进行后一种求解。本文旨在探讨支持向量机在预测全球新生儿死亡主要原因方面的潜力和局限性。我们检索了利用SVM预测脓毒症、癫痫发作、胎心率、低出生体重、缺氧缺血性脑病、呼吸暂停、黄疸、新生儿呼吸窘迫综合征等不同疾病和症状的文章,发现SVM有其优点,在许多方面显示出良好的效果,但也有缺点,需要大量的训练时间才能达到更高的准确性和精度。
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引用次数: 0
Gestational diabetes screening and management: the issues of GDM risk factors and phone number documentations 妊娠期糖尿病筛查和管理:GDM危险因素和电话号码文件的问题
Pub Date : 2023-09-27 DOI: 10.18203/issn.2454-2156.intjscirep20232909
Fortunatus D. Gbeinbo, Phillip T. Bwititi, Ezekiel U. Nwose
Background: Gestational diabetes mellitus (GDM) if unmanaged can complicate pregnancy outcomes. Selective screening of GDM is a common policy hence, the need for complete medical records of patients. The extent and pattern that documentation of patients’ records can impact GDM screening-by-telehealth requires elucidation. The aim was to describe the effectiveness of phone contacts on medical records and GDM risk factors among a hospital-based antenatal clinic setting Methods: This was an observational study in which previously reported antenatal records of patients screened for GDM were reviewed for effectiveness of phone contacts to do telehealth, and this was with simultaneous GDM risk assessment. Data were analysed by descriptive frequency counting. Results: On effectiveness of phone details on medical records, 41/98 cases were reached, of which 31.7% have three or more GDM risk factors to fulfil selection criteria for laboratory screening of GDM. Prevalence of risk factors in initial routine data collection (24.9%), previous history assessment (21.3%) and at antenatal monitoring phase (37.8%), Among the 57/98 phone contacts that were unreached, 59.6% are switched off. Conclusions: The observations highlight the need of concerted focus on policy and education, for both staff and patients, to improve documentation of correct and valid telephone details in medical records.
背景:妊娠期糖尿病(GDM)如果不加以控制会使妊娠结局复杂化。GDM的选择性筛查是一项普遍政策,因此需要完整的患者医疗记录。患者记录的程度和模式可以影响GDM远程医疗筛查需要阐明。目的是描述医院产前诊所设置中电话联系对医疗记录和GDM风险因素的有效性。方法:这是一项观察性研究,回顾了先前报道的GDM筛查患者的产前记录,以了解电话联系进行远程医疗的有效性,同时进行了GDM风险评估。采用描述性频率计数法分析数据。结果:病历电话信息的有效性达到41/98,其中有3个及以上GDM危险因素符合GDM实验室筛查选择标准的占31.7%。在最初的常规资料收集(24.9%)、既往史评估(21.3%)和产前监测阶段(37.8%)中危险因素的流行程度,在未联系的57/98电话联系人中,59.6%被关闭。结论:观察结果突出表明,需要协调一致地注重政策和对工作人员和患者的教育,以改进病历中正确有效的电话详细信息的记录。
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引用次数: 0
LC16m8: long term immunity is the way to eradicate monkey pox LC16m8:长期免疫是根除猴痘的途径
Pub Date : 2023-09-27 DOI: 10.18203/issn.2454-2156.intjscirep20232914
Ahmad Shahid, Maheera Khan, Manahil Mubeen, Affan Abid
Another addition to the trend of infectious epidemic diseases instituted by Corona Virus is the monkey pox virus, a concept endemic to the nations of Africa but now globalized in the 2022-2023 epidemic.
由冠状病毒引起的传染性流行病趋势的另一个新成员是猴痘病毒,这是非洲国家特有的概念,但现在在2022-2023年的流行病中全球化了。
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引用次数: 0
Intimate partner violence; breaking the silence on male victims in Nigeria 亲密伴侣暴力;打破了对尼日利亚男性受害者的沉默
Pub Date : 2023-09-27 DOI: 10.18203/issn.2454-2156.intjscirep20232913
Gbolahan D. Olatunji, Entonu I. Alexander, Samson Ojedokun
Globally, men have always been seen as perpetrators of aggression in romantic relationship which constitute intimate partner violence (IPV). In Nigeria, they are mostly considered as the villains due to the patriarchal nature of the society. However, there have many cases of violence by intimate partners where men were the victims. Very few of such cases were reported either to the hospital or to the police due to many reasons ranging from sociocultural, ethnic, economic and religious values among others. In a patriarchal society like Nigeria, men experience various form of violence which could be physical, psychological, sexual and socioeconomic from intimate partners. Therefore, this article attempts to review the reported incidence of male victims of IPV in Nigeria and the peculiarities involved while providing recommendations. Some of the factors identified for the low incidence report includes; lack of routine screening for domestic violence in health facilities, the fact that psychological violence is not considered as violence in some Nigerian society, shame about disclosing family violence, poor socioeconomic status and many more. Additionally, a major predictor of female-perpetrated IPV was childhood exposure to violence. This paper recommends that several actions which would improve the report of IPV against men while ameliorating IPV in Nigeria may involve: raising public awareness, legal protection, increasing health care worker sensitivity, provision of support services, research and proper data collection among others.
在全球范围内,男性一直被视为浪漫关系中侵犯行为的肇事者,构成亲密伴侣暴力。在尼日利亚,由于社会的父权性质,他们大多被认为是恶棍。然而,在许多亲密伴侣施暴的案件中,男性是受害者。由于社会文化、种族、经济和宗教价值观等诸多原因,很少有人向医院或警方报告这类案件。在尼日利亚这样的父权社会中,男性会遭受来自亲密伴侣的各种形式的暴力,包括身体、心理、性和社会经济暴力。因此,本文试图审查报告的IPV在尼日利亚的男性受害者的发病率和特殊性,同时提供建议。低发病率报告确定的一些因素包括:卫生机构缺乏对家庭暴力的常规筛查,心理暴力在某些尼日利亚社会不被视为暴力,对披露家庭暴力感到羞耻,社会经济地位低下等等。此外,女性实施IPV的一个主要预测因素是童年遭受暴力。本文建议采取若干行动,改善尼日利亚针对男子的IPV报告,同时改善IPV情况,这些行动可能涉及:提高公众认识、法律保护、提高保健工作者的敏感性、提供支助服务、研究和适当的数据收集等。
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引用次数: 0
Myoid hamartoma of breast: a rare case report with review of literature 乳房肌样错构瘤1例并文献复习
Pub Date : 2023-09-27 DOI: 10.18203/issn.2454-2156.intjscirep20232911
Nimisha Dhankar, Nita Khurana, Jyoti Kumar, Sushanto Neogi
Myoid hamartomas of breast are extremely rare lesions with poorly defined pathogenesis. They are composed of differentiated mammary glandular and stromal structures with areas of smooth muscle differentiation. They are postulated to arise from walls of the blood vessels and/or muscularis mammillae of the areolae. They usual present as a well demarcated lump and it is difficult to diagnose them on clinical and radiological basis. Diagnosis requires demonstration of smooth muscle phenotype using immunohistochemistry by smooth muscle actin and desmin. Surgical resection is the curative treatment. We reported a case of myoid hamartoma in a 50-year-old postmenopausal lady with its clinical, radiological and histopathological discussion. The lesion presented as a painless lump and was initially reported as BIRADS 4a on mammography. Apart from the stroma showing spindle cell component with smooth muscle differentiation, the histopathology also showed epithelial changes including epithelial hyperplasia and columnar cell change.
摘要乳房肌样错构瘤是极为罕见的病变,其发病机制不明确。它们由分化的乳腺和间质结构组成,并有平滑肌分化区。它们被认为起源于血管壁和/或乳晕的乳头肌层。它们通常表现为界限清楚的肿块,难以在临床和放射学基础上诊断。诊断需要使用平滑肌肌动蛋白和desmin的免疫组织化学来证明平滑肌表型。手术切除是根治性治疗。我们报告了一例50岁绝经后妇女的肌样错构瘤,并对其临床、影像学和组织病理学进行了讨论。病变表现为无痛性肿块,最初在乳房x光检查中报告为BIRADS 4a。除间质呈梭形细胞成分,平滑肌分化外,组织病理学还显示上皮增生和柱状细胞改变。
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引用次数: 0
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International Journal of Scientific Reports
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