Pub Date : 2019-10-31DOI: 10.26438/ijsrbs/v6i5.1518
G. Suja, T. V. Kumar, P. Suganya
The present study attempts to evaluate the phytochemical activity and in vitro anticancer activity of Eupatorium triplinerve methanol extract against lung cancer cell line A-549 and normal cell line Vero. The compound was analyzed for the presence of various phytoconstituents and screened for its cytotoxicity at five different concentrations by MTT assay. The phytochemical profile exhibited the presence of alkaloids, phenolics, flavonoids and steroids. The study documented that the percentage of cell viability has been reduced with the increased concentration, as evidenced by cell death. Eupatorium triplinerve extract shows potential cytotoxic activity with CTC50 of 450 μg/ml and 110 μg/ml against A-549 and Vero cell line respectively. The result obtained was comparably potent, the crude extract showed moderate activity against cancer cells and it was less toxic to the normal cells. In future, research need to be explored in the purification of this extract and identification of lead compound which could be used as a therapeutic tool against lung cancer.
{"title":"Evaluation of Phytochemicals and In Vitro Anticancer Activity of Eupatorium Triplinerve","authors":"G. Suja, T. V. Kumar, P. Suganya","doi":"10.26438/ijsrbs/v6i5.1518","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i5.1518","url":null,"abstract":"The present study attempts to evaluate the phytochemical activity and in vitro anticancer activity of Eupatorium triplinerve methanol extract against lung cancer cell line A-549 and normal cell line Vero. The compound was analyzed for the presence of various phytoconstituents and screened for its cytotoxicity at five different concentrations by MTT assay. The phytochemical profile exhibited the presence of alkaloids, phenolics, flavonoids and steroids. The study documented that the percentage of cell viability has been reduced with the increased concentration, as evidenced by cell death. Eupatorium triplinerve extract shows potential cytotoxic activity with CTC50 of 450 μg/ml and 110 μg/ml against A-549 and Vero cell line respectively. The result obtained was comparably potent, the crude extract showed moderate activity against cancer cells and it was less toxic to the normal cells. In future, research need to be explored in the purification of this extract and identification of lead compound which could be used as a therapeutic tool against lung cancer.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91054066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.89100
A. Ammanagi, A. Badiger, C T Shivasharana
{"title":"Bioprospecting of Fungi for Melanin fabrication A Comprehensive Review","authors":"A. Ammanagi, A. Badiger, C T Shivasharana","doi":"10.26438/ijsrbs/v6i4.89100","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.89100","url":null,"abstract":"","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82457252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.6888
P. Ganesan, S. Rajan, D. Magesh, T. Williamraja, M. G. Paulraj, S. Ignacimuthu
Essential oils from medicinal plants are widely used all over the world as insect repellents as they are highly safe and beneficial to environment with least ill-effects on animal and public health. Electronic databases including Science direct, PubMed, Scopus, Cochrane library and Scifinder were searched for papers on essential oils from plants with mosquito repellent efficacy. Ethnobotany, phytochemistry and repellent efficacy of plant essential oils were also discussed in this review. This review discusses in detail the mosquito-repellent plant essential oils which would be helpful in effective formulation of different essential oils for efficient control of mosquitoes, thus vector-borne diseases and for pharmacological studies, i.e., drug designing. This review would assist in finding studies on different mosquito-repellent plant essential oils at one stop, since it summarizes a large number of reports on essential oils.
{"title":"Essential Oils from Plants A Review on Eco-Friendly Mosquito Repellents","authors":"P. Ganesan, S. Rajan, D. Magesh, T. Williamraja, M. G. Paulraj, S. Ignacimuthu","doi":"10.26438/ijsrbs/v6i4.6888","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.6888","url":null,"abstract":"Essential oils from medicinal plants are widely used all over the world as insect repellents as they are highly safe and beneficial to environment with least ill-effects on animal and public health. Electronic databases including Science direct, PubMed, Scopus, Cochrane library and Scifinder were searched for papers on essential oils from plants with mosquito repellent efficacy. Ethnobotany, phytochemistry and repellent efficacy of plant essential oils were also discussed in this review. This review discusses in detail the mosquito-repellent plant essential oils which would be helpful in effective formulation of different essential oils for efficient control of mosquitoes, thus vector-borne diseases and for pharmacological studies, i.e., drug designing. This review would assist in finding studies on different mosquito-repellent plant essential oils at one stop, since it summarizes a large number of reports on essential oils.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75298864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.1216
M. Bencela, S. Kumari, T. S. Parmila
Ni(II) and Zn(II) metal complexes with Schiff base derived from Citral and Valine are synthesised and characterized on the basis of spectroscopic techniques (FT-IR, and UV-Visible) and magnetic susceptibility studies The IR spectral data indicated that the Schiff base coordinated to central Ni(II) and Zn(II) ions in a bridged-tridentate and bidentate fashion respectively. Magnetic moment and spectral studies suggest distorted octahedral around the Ni(II) ion and tetrahedral geomtry around Zn(II) ion. The preliminary antimicrobial activity has been evaluated against two Gram-negative bacteria; namely, Pseudomonas aeroginosa and Escherichia coli, one gram-positive bacteria Staphylococcus aureus, and antifungal activity are tested against Aspergillus sps and Candida albicans using disc diffusion method. The result revealed that Ni(II) complex exhibited potent activity when compared to Zn(II) complex and Schiff base. Keywords— Schiff base, Citral, valine, metal complexes, antimicrobial activity.
{"title":"Investigation on Antimicrobial Activity of Nickel(II) and Zinc(II) Complexes with Schiff Base Derived from Aminoacid Valine With Citral Synthesis, Spectroscopic Analysis","authors":"M. Bencela, S. Kumari, T. S. Parmila","doi":"10.26438/ijsrbs/v6i4.1216","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.1216","url":null,"abstract":"Ni(II) and Zn(II) metal complexes with Schiff base derived from Citral and Valine are synthesised and characterized on the basis of spectroscopic techniques (FT-IR, and UV-Visible) and magnetic susceptibility studies The IR spectral data indicated that the Schiff base coordinated to central Ni(II) and Zn(II) ions in a bridged-tridentate and bidentate fashion respectively. Magnetic moment and spectral studies suggest distorted octahedral around the Ni(II) ion and tetrahedral geomtry around Zn(II) ion. The preliminary antimicrobial activity has been evaluated against two Gram-negative bacteria; namely, Pseudomonas aeroginosa and Escherichia coli, one gram-positive bacteria Staphylococcus aureus, and antifungal activity are tested against Aspergillus sps and Candida albicans using disc diffusion method. The result revealed that Ni(II) complex exhibited potent activity when compared to Zn(II) complex and Schiff base. Keywords— Schiff base, Citral, valine, metal complexes, antimicrobial activity.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83111049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.5155
Rajkumar T. Pawar, T. Pathan, Y. Bhosale
An avifaunal survey was conducted at Majalgaon Reservoir for two years, starting from July 2016 to June 2018. The study reveals a rich avian diversity a total of 84 species of birds belonging to 15 orders and 30 families were identified. As the water of the wetland is clear, rich in dissolved oxygen and supports variety of aquatic weeds and fishes, it has been found to be suitable for birds and attracts many migratory birds like large egert, purple heron, white bellied heron, asian open bill stork, greater flamingo, white naked stork etc. Continuous monitoring on the avifaunal diversity was suggested to evaluate the ecological status of the habitats and birds. It can be considered as an efficient tool to the environmentalists, policy makers in order to conserve such species, because, the role of birds in an ecosystem cannot be ignored.
{"title":"Avifaunal study of Majalgaon Reservoir and their tributaries, District Beed, Marathwada region of Maharashtra, India","authors":"Rajkumar T. Pawar, T. Pathan, Y. Bhosale","doi":"10.26438/ijsrbs/v6i4.5155","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.5155","url":null,"abstract":"An avifaunal survey was conducted at Majalgaon Reservoir for two years, starting from July 2016 to June 2018. The study reveals a rich avian diversity a total of 84 species of birds belonging to 15 orders and 30 families were identified. As the water of the wetland is clear, rich in dissolved oxygen and supports variety of aquatic weeds and fishes, it has been found to be suitable for birds and attracts many migratory birds like large egert, purple heron, white bellied heron, asian open bill stork, greater flamingo, white naked stork etc. Continuous monitoring on the avifaunal diversity was suggested to evaluate the ecological status of the habitats and birds. It can be considered as an efficient tool to the environmentalists, policy makers in order to conserve such species, because, the role of birds in an ecosystem cannot be ignored.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80715829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.5661
Snigdha Singh, I. Chaudhary, Pankaj Kumar
Rapid urbanization and industrialization are the leading causes of environmental pollution nowadays. Heavy metals are serious toxic pollutants in soil, water, and air environments. Anthropogenic activity including industrial waste and dust is a widely known source for metal pollution. Various techniques are being used including ion-exchange, membrane filtration, electrolysis, coagulation, flotation, and adsorption for the removal of heavy metals from the environment. However, these techniques have high operating cost, sludge generation and selectivity of metals. Among them, heavy metal removal by the plant is an eco-friendly, sustainable, rapid and economic process. The adsorbent capacity of metal ions by plant and its removal varies, depending on the nature of the plants, particle size, and metal concentrations. This review paper focuses on the idea of using various agricultural wastes for the removal of heavy metals and also a way to management of waste generated by agriculture field. In this context, agricultural biomass is the best technique for the removal of heavy metals and need to improve the utilization of agricultural waste as sustainable way.
{"title":"Utilization of Low-cost Agricultural Waste for Removal of Toxic Metals from Environment A Review","authors":"Snigdha Singh, I. Chaudhary, Pankaj Kumar","doi":"10.26438/ijsrbs/v6i4.5661","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.5661","url":null,"abstract":"Rapid urbanization and industrialization are the leading causes of environmental pollution nowadays. Heavy metals are serious toxic pollutants in soil, water, and air environments. Anthropogenic activity including industrial waste and dust is a widely known source for metal pollution. Various techniques are being used including ion-exchange, membrane filtration, electrolysis, coagulation, flotation, and adsorption for the removal of heavy metals from the environment. However, these techniques have high operating cost, sludge generation and selectivity of metals. Among them, heavy metal removal by the plant is an eco-friendly, sustainable, rapid and economic process. The adsorbent capacity of metal ions by plant and its removal varies, depending on the nature of the plants, particle size, and metal concentrations. This review paper focuses on the idea of using various agricultural wastes for the removal of heavy metals and also a way to management of waste generated by agriculture field. In this context, agricultural biomass is the best technique for the removal of heavy metals and need to improve the utilization of agricultural waste as sustainable way.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79715908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.4350
G. Indravathi, P. S. Babu
The anatomical, morphological and physiological characteristics of the in vitro developed micro shoots, for a majority of the woody species, have a great impact on subsequent rooting and survival after transfer to greenhouse conditions. Any effort to improve these characteristics by controlling the stressful culture conditions undoubtedly contributes to better rooting of micro cuttings and/or acclimatization of the microplants. In the present investigation, timber yielding leguminous tree, Albizia amara has been selected for micropropagation owing to their, importance as a plant with potential medicinal value. Micropropagated plantlets usually exhibit high mortality rate upon their transfer from lab to land as a result of transplantation shock caused by abiotic and biotic stresses and weak root system. Biotization is the metabolic response of in vitro grown plant material to a microbial inoculum. It leads to morphological and physiological development of plant material thereby enhancing biotic and abiotic stress resistance. The in vitro grown micro shoots of Albizia amara with root primordia were treated with bio inoculants namely Pseudomonas fluorescens and Trichoderma viride and transferred to plastic pots containing sterilized potting mixture (soil: peat : vermiculite: perlite in 2:1:1:1). There were four treatments viz. control, treatment with T . v i r i d e and P. fluorescens separately and dual inoculation. Percent survival of plantlets was observed maximum (82%) in dual inoculation, this must be due to the positive interaction between T.viride and P. fluorescens and their ability to enhance stress tolerance by protecting them from subsequent „transplantation shock‟. These plantlets also exhibited an increase in root length, the number of lateral roots, shoot length, leaf number, and plant biomass .
{"title":"Enhancing acclimatization of tissue cultured plants of Albizia amara by Biotization","authors":"G. Indravathi, P. S. Babu","doi":"10.26438/ijsrbs/v6i4.4350","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.4350","url":null,"abstract":"The anatomical, morphological and physiological characteristics of the in vitro developed micro shoots, for a majority of the woody species, have a great impact on subsequent rooting and survival after transfer to greenhouse conditions. Any effort to improve these characteristics by controlling the stressful culture conditions undoubtedly contributes to better rooting of micro cuttings and/or acclimatization of the microplants. In the present investigation, timber yielding leguminous tree, Albizia amara has been selected for micropropagation owing to their, importance as a plant with potential medicinal value. Micropropagated plantlets usually exhibit high mortality rate upon their transfer from lab to land as a result of transplantation shock caused by abiotic and biotic stresses and weak root system. Biotization is the metabolic response of in vitro grown plant material to a microbial inoculum. It leads to morphological and physiological development of plant material thereby enhancing biotic and abiotic stress resistance. The in vitro grown micro shoots of Albizia amara with root primordia were treated with bio inoculants namely Pseudomonas fluorescens and Trichoderma viride and transferred to plastic pots containing sterilized potting mixture (soil: peat : vermiculite: perlite in 2:1:1:1). There were four treatments viz. control, treatment with T . v i r i d e and P. fluorescens separately and dual inoculation. Percent survival of plantlets was observed maximum (82%) in dual inoculation, this must be due to the positive interaction between T.viride and P. fluorescens and their ability to enhance stress tolerance by protecting them from subsequent „transplantation shock‟. These plantlets also exhibited an increase in root length, the number of lateral roots, shoot length, leaf number, and plant biomass .","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85701611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.101104
N. Sisodia, S. Gaherwal, R. Jain
The present study deals with the determination of different disease and preventive measures of mulberry silkworm, (Bombyx mori). Epizootiology, development of immunodiagnostic kit, fluorescent antibody technique and use of ideal disinfectant, chemotherapy and thermo-therapy techniques and management strategies have been addressed for identification, destruction, prevention and control of disease causing micro-organisms. Three years survey was conducted on the incidence of silkworm diseases namely, Grasserie, Flacherie, Muscardine and pebrine, the data revealed that grasserie and flacherie incidence were maximum in summer season and minimum in winter season whereas muscardine was observed high in winter.
{"title":"Determination of Different Diseases and Preventive Measures of Mulberry Silkworm","authors":"N. Sisodia, S. Gaherwal, R. Jain","doi":"10.26438/ijsrbs/v6i4.101104","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.101104","url":null,"abstract":"The present study deals with the determination of different disease and preventive measures of mulberry silkworm, (Bombyx mori). Epizootiology, development of immunodiagnostic kit, fluorescent antibody technique and use of ideal disinfectant, chemotherapy and thermo-therapy techniques and management strategies have been addressed for identification, destruction, prevention and control of disease causing micro-organisms. Three years survey was conducted on the incidence of silkworm diseases namely, Grasserie, Flacherie, Muscardine and pebrine, the data revealed that grasserie and flacherie incidence were maximum in summer season and minimum in winter season whereas muscardine was observed high in winter.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77144605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.2932
K. Jaleel, S. Ghosh, V. Joseph
All Severe incidence of banana leaf roller Erionota spp. has been noticed in banana plantations of Malabar region of Kerala a part of Western Ghat, India. It is currently proposed that banana defoliater E. thrax and E. torus occur together in Kerala and many researchers have treated them as a single species. At present there is no published information regarding whether, one or both the species of Erionota coexist during the occasional outbreak of banana skipper in Kerala.Also it is unknown whether in the field the associated parasitoids attack both species ,equally or showed some preference for one or the other .This information is essential for the implementation of effective biological control programmes against this pest. Since the early stages of E. thrax and E. torus cannot be distinguished easily , and as they are common pests of banana, morphological identification of species is difficult. The present study is aimed to confirm the Erionota species from Malabar region of Kerala by using a molecular genetic approach. We sequenced the partial mitochondrial cytochrome oxidase I gene sequence (COI ) having 650 base pair DNA from specimens collected from selected localities of Malabar region of Kerala ,India. The COI sequences of the banana skipper supported the existence of E.torus species in the infested areas and all the parasitoid species collected during the course of study where that of E.torus . Keywords—Erionota torus,Erionota thrax,COX I,DNA barcoding ,Musa spp.
{"title":"DNA barcoding and evolutionary lineage of banana skipper Erionota torus (Evans) (Lepidoptera Hesperiidae) from Malabar, a part of Southern WesternGhats, India","authors":"K. Jaleel, S. Ghosh, V. Joseph","doi":"10.26438/ijsrbs/v6i4.2932","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.2932","url":null,"abstract":"All Severe incidence of banana leaf roller Erionota spp. has been noticed in banana plantations of Malabar region of Kerala a part of Western Ghat, India. It is currently proposed that banana defoliater E. thrax and E. torus occur together in Kerala and many researchers have treated them as a single species. At present there is no published information regarding whether, one or both the species of Erionota coexist during the occasional outbreak of banana skipper in Kerala.Also it is unknown whether in the field the associated parasitoids attack both species ,equally or showed some preference for one or the other .This information is essential for the implementation of effective biological control programmes against this pest. Since the early stages of E. thrax and E. torus cannot be distinguished easily , and as they are common pests of banana, morphological identification of species is difficult. The present study is aimed to confirm the Erionota species from Malabar region of Kerala by using a molecular genetic approach. We sequenced the partial mitochondrial cytochrome oxidase I gene sequence (COI ) having 650 base pair DNA from specimens collected from selected localities of Malabar region of Kerala ,India. The COI sequences of the banana skipper supported the existence of E.torus species in the infested areas and all the parasitoid species collected during the course of study where that of E.torus . Keywords—Erionota torus,Erionota thrax,COX I,DNA barcoding ,Musa spp.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74013970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-31DOI: 10.26438/ijsrbs/v6i4.2228
Ajitha S. Nair, Aparna V. Dubhashi
This work encompasses the use of a sporulating probiotic culture, Brevibacillus borstelensis, to prepare a nutraceutical product with a mixed fruit juice as a carrier for the culture. Lyophilization of the formulation was carried out using different dehydrating agents, pectin, ascorbic acid, gelatin, gum Arabic and maltodextrin in specific permissible concentrations. Pectin gave the best results in terms of consistency and appearance of the nutraceutical powder, hence was used in the final formulation. The nutraceutical powder was then analysed for its shelf life, physical, chemical and nutritional profile. It was also tested for heavy metal contaminants, antibacterial activity and cholesterol reduction capability. Microbiological safety of the formulation was verified according to FSSAI manual. Encouraging results were obtained from the analyses. Lyophilization helped retain the nutrients of the fruits as well as improved the keeping quality of the formulation. The novel probiotic containing nutraceutical powder prepared could be helpful to lactose intolerant population. Its cholesterol reduction property could be beneficial to hypercholesteraemic individuals.
{"title":"Novel Fruit Juice Based Nutraceutical Formulation with Probiotic and Cholesterol Reduction Properties","authors":"Ajitha S. Nair, Aparna V. Dubhashi","doi":"10.26438/ijsrbs/v6i4.2228","DOIUrl":"https://doi.org/10.26438/ijsrbs/v6i4.2228","url":null,"abstract":"This work encompasses the use of a sporulating probiotic culture, Brevibacillus borstelensis, to prepare a nutraceutical product with a mixed fruit juice as a carrier for the culture. Lyophilization of the formulation was carried out using different dehydrating agents, pectin, ascorbic acid, gelatin, gum Arabic and maltodextrin in specific permissible concentrations. Pectin gave the best results in terms of consistency and appearance of the nutraceutical powder, hence was used in the final formulation. The nutraceutical powder was then analysed for its shelf life, physical, chemical and nutritional profile. It was also tested for heavy metal contaminants, antibacterial activity and cholesterol reduction capability. Microbiological safety of the formulation was verified according to FSSAI manual. Encouraging results were obtained from the analyses. Lyophilization helped retain the nutrients of the fruits as well as improved the keeping quality of the formulation. The novel probiotic containing nutraceutical powder prepared could be helpful to lactose intolerant population. Its cholesterol reduction property could be beneficial to hypercholesteraemic individuals.","PeriodicalId":14378,"journal":{"name":"International Journal of Scientific Research in Biological Sciences","volume":"106 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80680877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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