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JACC. Cardiovascular interventions最新文献

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100.15 Diagnostic Implications of Circulating Micro RNAs 208a and 223-3p in Patients With Coronary Artery Disease
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.088
Mohammed S. Gomaa (Dr)
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引用次数: 0
100.83 The Efficacy of Glycoprotein IIb/IIIa Inhibitors in Achieving TIMI 3 Flow in Acute Coronary Syndrome Patients With Large Thrombus Burden: A Meta-Analysis
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.117
Mehmet Cilingiroglu, Cezar Iliescu, Kostas Marmagkiolis, Ibrahim Inanc
{"title":"100.83 The Efficacy of Glycoprotein IIb/IIIa Inhibitors in Achieving TIMI 3 Flow in Acute Coronary Syndrome Patients With Large Thrombus Burden: A Meta-Analysis","authors":"Mehmet Cilingiroglu, Cezar Iliescu, Kostas Marmagkiolis, Ibrahim Inanc","doi":"10.1016/j.jcin.2025.01.117","DOIUrl":"10.1016/j.jcin.2025.01.117","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Page S34"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
100.39 Traditional Risk Factors are not Associated With Development of Allograft Vasculopathy, but They are Associated With More Severe Lesion Requiring Percutaneous Coronary Intervention
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.093
Mehrtash Hashemzadeh , Mohammad Reza Movahed
{"title":"100.39 Traditional Risk Factors are not Associated With Development of Allograft Vasculopathy, but They are Associated With More Severe Lesion Requiring Percutaneous Coronary Intervention","authors":"Mehrtash Hashemzadeh , Mohammad Reza Movahed","doi":"10.1016/j.jcin.2025.01.093","DOIUrl":"10.1016/j.jcin.2025.01.093","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Page S28"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Clinical Outcomes After IFR- vs FFR-Guided Coronary Revascularization
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2024.12.003
Matthias Götberg MD, PhD , Karolina Berntorp MD , Allen Jeremias MD, MSc , Troels Yndigegn MD, PhD , Sacharias von Koch MD , Rickard Linder MD, PhD , Sasha Koul MD, PhD , Ole Fröbert MD, PhD , David Erlinge MD, PhD , Moman A. Mohammad MD, PhD

Background

Long-term data on safety and efficacy of instantaneous wave-free ratio (IFR) vs fractional flow reserve (FFR) in guiding percutaneous coronary intervention (PCI) is lacking.

Objectives

This study sought to evaluate the 5-year clinical outcomes of IFR- vs FFR-guided PCI in a real-world setting.

Methods

We assessed the 5-year outcomes of all patients undergoing IFR or FFR assessment between January 1, 2014, and February 16, 2022, using data from the SWEDEHEART (Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies) registry. Two-to-1 propensity score matching was used to adjust for differences between groups. Additional analyses adjusted for propensity score, PCI center, and baseline differences remaining after matching were conducted. The primary outcome was major adverse cardiac events (MACE) defined as first occurrence of all-cause death, myocardial infarction, or repeat revascularization within 5 years.

Results

Among 16,152 (65.6%) of 24,623 FFR and 8,471 (34.4%) of 24,623 IFR patients, IFR led to more frequent deferral of revascularization (5,964 of 8,471 [70.4%] vs 10,615 of 24,623 [65.7%]; P < 0.001). There was no significant difference in Kaplan-Meier event rates in MACE at 5 years between patients who underwent IFR or FFR-guided revascularization (1,993 [31.3% (95% CI: 30.0%-32.6%)] vs 3,961 [31.9% (95% CI: 31.0%-32.8%)]; adjusted HR: 0.96; 95% CI: 0.82-1.12; P = 0.60), including all-cause death, cardiovascular death, cardiac death, coronary death, new myocardial infarction, or revascularization. Subgroup analysis of deferred and treated patients revealed no difference between groups regarding MACE or its individual components.

Conclusions

In a large nationwide registry of patients undergoing physiology-based coronary revascularization, there were no significant differences in MACE or all-cause mortality between IFR and FFR-guided revascularization at 5 years.
{"title":"Long-Term Clinical Outcomes After IFR- vs FFR-Guided Coronary Revascularization","authors":"Matthias Götberg MD, PhD ,&nbsp;Karolina Berntorp MD ,&nbsp;Allen Jeremias MD, MSc ,&nbsp;Troels Yndigegn MD, PhD ,&nbsp;Sacharias von Koch MD ,&nbsp;Rickard Linder MD, PhD ,&nbsp;Sasha Koul MD, PhD ,&nbsp;Ole Fröbert MD, PhD ,&nbsp;David Erlinge MD, PhD ,&nbsp;Moman A. Mohammad MD, PhD","doi":"10.1016/j.jcin.2024.12.003","DOIUrl":"10.1016/j.jcin.2024.12.003","url":null,"abstract":"<div><h3>Background</h3><div>Long-term data on safety and efficacy of instantaneous wave-free ratio (IFR) vs fractional flow reserve (FFR) in guiding percutaneous coronary intervention (PCI) is lacking.</div></div><div><h3>Objectives</h3><div>This study sought to evaluate the 5-year clinical outcomes of IFR- vs FFR-guided PCI in a real-world setting.</div></div><div><h3>Methods</h3><div>We assessed the 5-year outcomes of all patients undergoing IFR or FFR assessment between January 1, 2014, and February 16, 2022, using data from the SWEDEHEART (Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommended Therapies) registry. Two-to-1 propensity score matching was used to adjust for differences between groups. Additional analyses adjusted for propensity score, PCI center, and baseline differences remaining after matching were conducted. The primary outcome was major adverse cardiac events (MACE) defined as first occurrence of all-cause death, myocardial infarction, or repeat revascularization within 5 years.</div></div><div><h3>Results</h3><div>Among 16,152 (65.6%) of 24,623 FFR and 8,471 (34.4%) of 24,623 IFR patients, IFR led to more frequent deferral of revascularization (5,964 of 8,471 [70.4%] vs 10,615 of 24,623 [65.7%]; <em>P</em> &lt; 0.001). There was no significant difference in Kaplan-Meier event rates in MACE at 5 years between patients who underwent IFR or FFR-guided revascularization (1,993 [31.3% (95% CI: 30.0%-32.6%)] vs 3,961 [31.9% (95% CI: 31.0%-32.8%)]; adjusted HR: 0.96; 95% CI: 0.82-1.12; <em>P</em> = 0.60), including all-cause death, cardiovascular death, cardiac death, coronary death, new myocardial infarction, or revascularization. Subgroup analysis of deferred and treated patients revealed no difference between groups regarding MACE or its individual components.</div></div><div><h3>Conclusions</h3><div>In a large nationwide registry of patients undergoing physiology-based coronary revascularization, there were no significant differences in MACE or all-cause mortality between IFR and FFR-guided revascularization at 5 years.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Pages 455-467"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143479994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
100.25 Impact of Cangrelor on Patients With Acute Myocardial Infarction-Induced Cardiogenic Shock Undergoing Percutaneous Coronary Intervention
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.105
Waiel Abusnina, Kalyan R. Chitturi, Beni R. Verma, Abhishek Chaturvedi, Lior Lupu, Dan Haberman, Jason Galo, Matteo Cellamare, Vaishnavi Sawant, Sevket Ozturk, Cheng Zhang, Itsik Ben-Dor, Hayder D. Hashim, Brian C. Case, Ron Waksman
{"title":"100.25 Impact of Cangrelor on Patients With Acute Myocardial Infarction-Induced Cardiogenic Shock Undergoing Percutaneous Coronary Intervention","authors":"Waiel Abusnina,&nbsp;Kalyan R. Chitturi,&nbsp;Beni R. Verma,&nbsp;Abhishek Chaturvedi,&nbsp;Lior Lupu,&nbsp;Dan Haberman,&nbsp;Jason Galo,&nbsp;Matteo Cellamare,&nbsp;Vaishnavi Sawant,&nbsp;Sevket Ozturk,&nbsp;Cheng Zhang,&nbsp;Itsik Ben-Dor,&nbsp;Hayder D. Hashim,&nbsp;Brian C. Case,&nbsp;Ron Waksman","doi":"10.1016/j.jcin.2025.01.105","DOIUrl":"10.1016/j.jcin.2025.01.105","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Page S32"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
200.08 Radiofrequency Renal Denervation Improves Cardiac Energetics: 3-month Analysis From SPYRAL HTN-OFF MED
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.122
Joachim Weil , Laura Nickel , Felix Mahfoud , David E. Kandzari , Raymond R. Townsend , Kazuomi Kario , Michael A. Weber , Roland E. Schmieder , Konstantinos Tsioufis , Minglei Liu , Michael Böhm
{"title":"200.08 Radiofrequency Renal Denervation Improves Cardiac Energetics: 3-month Analysis From SPYRAL HTN-OFF MED","authors":"Joachim Weil ,&nbsp;Laura Nickel ,&nbsp;Felix Mahfoud ,&nbsp;David E. Kandzari ,&nbsp;Raymond R. Townsend ,&nbsp;Kazuomi Kario ,&nbsp;Michael A. Weber ,&nbsp;Roland E. Schmieder ,&nbsp;Konstantinos Tsioufis ,&nbsp;Minglei Liu ,&nbsp;Michael Böhm","doi":"10.1016/j.jcin.2025.01.122","DOIUrl":"10.1016/j.jcin.2025.01.122","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Pages S35-S36"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
101.04 Same-Day Discharge Percutaneous Coronary Intervention in Women
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.102
Juan Manuel Telayna Jr., Juan Ignacio Damonte, Juan Manuel Telayna, Ricardo Andres Costantini
{"title":"101.04 Same-Day Discharge Percutaneous Coronary Intervention in Women","authors":"Juan Manuel Telayna Jr.,&nbsp;Juan Ignacio Damonte,&nbsp;Juan Manuel Telayna,&nbsp;Ricardo Andres Costantini","doi":"10.1016/j.jcin.2025.01.102","DOIUrl":"10.1016/j.jcin.2025.01.102","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Page S31"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143478511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
100.02 Improving Outcomes in LAD Lesions - Insights From the BIOADAPTOR-RCT
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.084
Shigeru Saito , Johan Bennet , Holger M. Nef , Mark Webster , Stefan Verheye
{"title":"100.02 Improving Outcomes in LAD Lesions - Insights From the BIOADAPTOR-RCT","authors":"Shigeru Saito ,&nbsp;Johan Bennet ,&nbsp;Holger M. Nef ,&nbsp;Mark Webster ,&nbsp;Stefan Verheye","doi":"10.1016/j.jcin.2025.01.084","DOIUrl":"10.1016/j.jcin.2025.01.084","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Page S24"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143478723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
100.28 Meta-Analysis: Guideline-Directed Optimal Medical Therapy vs. Percutaneous Coronary Intervention for Chronic Total Occlusion Lesions With a Large Ischemic Burden
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.042
Mehmet Cilingiroglu, Cezar Iliescu, Kostas Marmagkiolis, Ibrahim Inanc
{"title":"100.28 Meta-Analysis: Guideline-Directed Optimal Medical Therapy vs. Percutaneous Coronary Intervention for Chronic Total Occlusion Lesions With a Large Ischemic Burden","authors":"Mehmet Cilingiroglu,&nbsp;Cezar Iliescu,&nbsp;Kostas Marmagkiolis,&nbsp;Ibrahim Inanc","doi":"10.1016/j.jcin.2025.01.042","DOIUrl":"10.1016/j.jcin.2025.01.042","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Page S11"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
100.49 Stents, Scalpel, or Stability: Revascularization in Patients Over 75 With Acute Coronary Syndrome
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
JACC. Cardiovascular interventions
Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.014
Samantha Pozo Navarro , Kendall Hammonds , Timothy Mixon , Jose Emilio Exaire , Christopher Douglas Chiles , Molly Szerlip , J. Michael DiMaio , R. Jay Widmer
{"title":"100.49 Stents, Scalpel, or Stability: Revascularization in Patients Over 75 With Acute Coronary Syndrome","authors":"Samantha Pozo Navarro ,&nbsp;Kendall Hammonds ,&nbsp;Timothy Mixon ,&nbsp;Jose Emilio Exaire ,&nbsp;Christopher Douglas Chiles ,&nbsp;Molly Szerlip ,&nbsp;J. Michael DiMaio ,&nbsp;R. Jay Widmer","doi":"10.1016/j.jcin.2025.01.014","DOIUrl":"10.1016/j.jcin.2025.01.014","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 4","pages":"Page S2"},"PeriodicalIF":11.7,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143480343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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