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100.33 Comparison of Clinical Outcomes Between First- and Second-Generation Drug-Eluting Stents in Multi-Vessel Disease Patients: 10-Year Follow-Up Results
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.081
Seung-Woon Rha , Byoung Geol Choi , Se Yeon Choi , Jinah Cha , Woo Jin Ahn , Wonsang Chu , Soohyung Park , Ji Young Park , Cheol Ung Choi , Chang Gyu Park
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引用次数: 0
100.69 Diagnostic And Prognostic Utility of FFR in In-Stent Restenosis
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.069
Malek Al-Hawwas , Srikanth Vallurupalli , Abdul Hakeem , Shiv Agarwal , Sandeep Randhawa , Barry Uretsky
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引用次数: 0
100.45 Clinical Outcomes Among Patients With Prior Coronary Artery Bypass Graft Surgery Undergoing Percutaneous Coronary Intervention of Native Vessel Versus Saphenous Vein Graft During Non-ST Elevation Myocardial Infarction
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.113
Beni Rai Verma , Abhinav Sood , Abhishek Chaturvedi , Abdullah K. Al Qaraghuli , Cheng Zhang , Sevket Ozturk , Vaishnavi Sawant , Jason Galo , Dan Haberman , Itsik Ben-Dor , Hayder Hashim , Ron Waksman
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引用次数: 0
100.23 Calcium Thickness and Stent Expansion for Concentric or Eccentric Calcified Lesions After Intravascular Lithotripsy 100.23 血管内碎石术后同心或偏心钙化病变的钙厚度和支架膨胀率
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.057
Koki Shishido, Yutaka Tanaka, Daisuke Sato, Masato Murakami, Shigeru Saito
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引用次数: 0
200.11 Transfemoral Carotid Artery Stenting Has Very Low Stroke, Death, and TIA Rates in Septuagenarians and Octogenarians in Hands of Experienced Interventional Cardiologists 200.11 经口颈动脉支架植入术在经验丰富的介入心脏病专家手中,七十岁和八十岁老人的中风、死亡和 TIA 发生率极低
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.127
Kevin Kang , Gurjaipal S. Kang , Robert L. Maholic , Silvia Kang , John S. Wilson
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引用次数: 0
Low-Gradient Severe Aortic Stenosis 低梯度重度主动脉瓣狭窄:来自当前AS登记的见解-2。
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2024.09.044
Tomohiko Taniguchi MD , Takeshi Morimoto MD, MPH , Yasuaki Takeji MD , Shinichi Shirai MD , Kenji Ando MD , Hiroyuki Tabata MD , Ko Yamamoto MD , Ryosuke Murai MD , Kohei Osakada MD , Hiroki Sakamoto MD , Tomohisa Tada MD , Koichiro Murata MD , Yuki Obayashi MD , Masashi Amano MD , Takeshi Kitai MD , Chisato Izumi MD , Mamoru Toyofuku MD , Norio Kanamori MD , Makoto Miyake MD , Hiroyuki Nakayama MD , Kouji Ueyama

Background

Low-gradient (LG) aortic stenosis (AS) has not been fully characterized compared with high-gradient (HG) AS in terms of cardiac damage, frailty, aortic valve calcification, and clinical outcomes.

Objectives

The aim of this study was to compare the clinical characteristics and outcomes between each hemodynamic type of LG AS and HG AS.

Methods

The current study included 3,363 patients in the CURRENT AS (Contemporary outcomes after sURgery and medical tREatmeNT in patients with severe Aortic Stenosis) Registry-2 after excluding patients without indexed stroke volume or left ventricular ejection fraction (LVEF) data. Patients were divided into 4 groups (LG AS with reduced LVEF: n = 285; paradoxical low flow, low gradient [LFLG]: n = 220; normal flow, low gradient [NFLG]: n = 872; HG: n = 1,986).

Results

Compared with HG AS, LG AS with reduced LVEF more often had cardiovascular comorbidities, advanced cardiac damage, and frailty with less severe valve calcification and paradoxical LFLG AS more often had atrial fibrillation, advanced cardiac damage, and frailty with less severe valve calcification, while NFLG AS had comparable cardiac damage and frailty with less severe valve calcification. Cumulative 3-year incidence of death or heart failure hospitalization was higher in LG AS with reduced LVEF and paradoxical LFLG than in HG AS. After adjusting for confounders, LG AS with reduced LVEF and paradoxical LFLG compared with HG AS were independently associated with higher risk for death or heart failure hospitalization (HR: 1.82; 95% CI: 1.49-2.23; P < 0.001; and HR: 1.43; 95% CI: 1.13-1.82; P = 0.003, respectively) but NFLG AS was not (HR: 1.03; 95% CI: 0.88-1.21; P = 0.68).

Conclusions

Clinical outcomes were significantly worse in LG AS with reduced LVEF and paradoxical LFLG AS and comparable in NFLG AS compared with HG AS.
背景:在心脏损伤、虚弱、主动脉瓣钙化和临床结果方面,低梯度(LG)主动脉瓣狭窄(AS)与高梯度(HG)主动脉瓣狭窄(AS)的特征尚未完全明确。目的:本研究的目的是比较各血流动力学类型的LG AS和HG AS的临床特征和结局。方法:目前的研究纳入了3363例患者,纳入了current AS(严重主动脉瓣狭窄患者手术和药物治疗后的当代结局)登记-2,排除了没有索引卒中容量或左心室射血分数(LVEF)数据的患者。患者分为4组(LVEF降低的LG AS: 285例;矛盾低流量,低梯度[LFLG]: n = 220;正常流量,低梯度[NFLG]: n = 872;HG: n = 1986)。结果:与HG AS相比,LVEF降低的LG AS更容易出现心血管合并症、晚期心脏损伤和虚弱,瓣膜钙化程度较轻;而矛盾LFLG AS更容易出现房颤、晚期心脏损伤和虚弱,瓣膜钙化程度较轻,而NFLG AS有类似的心脏损伤和虚弱,瓣膜钙化程度较轻。LVEF降低和矛盾LFLG的LG AS的累计3年死亡或心力衰竭住院发生率高于HG AS。在调整混杂因素后,与HG AS相比,LVEF降低的LG AS和矛盾的LFLG与死亡或心力衰竭住院的高风险独立相关(HR: 1.82;95% ci: 1.49-2.23;P < 0.001;HR: 1.43;95% ci: 1.13-1.82;P = 0.003),但NFLG AS无统计学意义(HR: 1.03;95% ci: 0.88-1.21;P = 0.68)。结论:与HG AS相比,LVEF降低的LG AS和矛盾的LFLG AS的临床结果明显更差,而NFLG AS的临床结果与HG AS相当。
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引用次数: 0
200.32 Mortality and Restenosis After Intracranial Stenting: Identifying Predictive Factors for 1-Year Survival
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.131
Yusuf Inanc , Ibrahim Halil Inanc , Yilmaz Inanc , Cengiz Sabanoglu , Esra Polat , Mesut Karatas , Mehmet Cilingiroglu
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引用次数: 0
100.32 Efficacy and Safety of Drug-Coated Balloons Compared to Drug-Eluting Stents in De-Novo Coronary Artery Disease: A Meta-Analysis
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.065
Saad Farooq , Mobeen Z. Haider , Abdul Qadeer , Muneeb Khawar , Saliha Maryam , Muhammad Haris Khan , Gaurav Kumar , Moosa Mubarika , Sultana Jahan , Yousra Khalid , Shazia Aziz , Robert W. Kirchoff , Muhammad Aamir , Nainesh Patel
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引用次数: 0
200.15 Twenty Four Week Safety and Efficacy of a Novel Extravascular Renal Denervation Device in a Porcine Model at an Elevated Temperature Setting
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2025.01.124
Chang Wook Jeong , Jay Budrewicz , John H. Keating , Misty Williams-Fritze , Peter Markham , Abraham R. Tzafriri
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引用次数: 0
Percutaneous Release of Thrombosed Mechanical Mitral Valve Leaflet
IF 11.7 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Pub Date : 2025-02-24 DOI: 10.1016/j.jcin.2024.11.029
Carlos Vergara Sanchez MD, Nahyr Lugo-Fagundo MD, Mays Ali MD, Jordan Ray MD, Prajwal Reddy MD, Michael S. Gharacholou MD, Abdallah El Sabbagh MD
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引用次数: 0
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JACC. Cardiovascular interventions
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