JACC. Cardiovascular interventions最新文献

{"title":"Atherectomy Is Not Associated With Improved Limb-Based Outcomes Among Patients in the BEST-CLI Trial Undergoing Endovascular Revascularization","authors":"Caitlin W. Hicks MD, MS ,&nbsp;Alik Farber MD, MBA ,&nbsp;Gheorghe Doros PhD, MBA ,&nbsp;Scott Kinlay MBBS, PhD ,&nbsp;Richard J. Powell MD ,&nbsp;Michael B. Strong MA ,&nbsp;Kenneth Rosenfield MD, MSc ,&nbsp;Hanaa Aridi MD ,&nbsp;Raghu Motaganahalli MD ,&nbsp;Andrew Barleben MD ,&nbsp;Jeffrey J. Siracuse MD ,&nbsp;Ezana Azene MD ,&nbsp;Mahmoud Malas MD ,&nbsp;Michael S. Conte MD ,&nbsp;Mohamed Zayed MD, PhD, MBA ,&nbsp;Matthew T. Menard MD","doi":"10.1016/j.jcin.2025.10.065","DOIUrl":"10.1016/j.jcin.2025.10.065","url":null,"abstract":"<div><h3>Background</h3><div>There are substantial data supporting the use of atherectomy for the treatment of coronary artery disease, but data regarding its efficacy for treating chronic limb-threatening ischemia (CLTI) are less robust.</div></div><div><h3>Objectives</h3><div>The authors aimed to evaluate the association of atherectomy with limb-based outcomes among patients managed with endovascular revascularization in the BEST-CLI (Best Endovascular vs Best Surgical Therapy in Patients With CLTI; <span><span>NCT02060630</span><svg><path></path></svg></span>) trial.</div></div><div><h3>Methods</h3><div>BEST-CLI was a prospective randomized trial comparing open and endovascular revascularization strategies for patients with CLTI. We included all patients treated with endovascular revascularization and stratified them according to whether they were treated with or without atherectomy. We evaluated whether atherectomy was associated with major adverse limb events (MALE) (including major reintervention or above-ankle amputation in the index limb) and secondary outcomes using Kaplan-Meier analyses and Cox proportional hazards models.</div></div><div><h3>Results</h3><div>923 patients underwent an endovascular intervention in the BEST-CLI trial (mean age 67.3 ± 10.0 years, 71.1%[656/923] male, 72.3%[662/916] White race), of which 132 (14.3%) received an atherectomy. After risk adjustment, MALE (adjusted HR [aHR]: 1.30; 95% CI: 0.92-1.84), major reintervention (aHR: 1.07; 95% CI: 0.67-1.73), above-ankle amputation (aHR: 1.32; 95% CI: 0.81-2.15), and all-cause death (aHR: 1.06; 95% CI: 0.75-1.49) were similar for patients who were treated with and without atherectomy. In a sensitivity analysis limited to patients with technical success, atherectomy was associated with higher MALE (unadjusted log-rank <em>P =</em> 0.02; aHR: 1.51; 95% CI: 1.03-2.22).</div></div><div><h3>Conclusions</h3><div>Atherectomy was associated with similar or slightly worse limb-based outcomes among patients undergoing endovascular revascularization for CLTI compared with other available endovascular technologies.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Pages 96-107"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S1936-8798(25)03221-2","DOIUrl":"10.1016/S1936-8798(25)03221-2","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Pages I-CXLVII"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRODIGY Reclassification May Alter the Meta-Analytical Results on Aspirin vs P2Y12 Inhibitor Monotherapy After Short DAPT","authors":"Grzegorz Procyk MD ,&nbsp;Kamil Tkacz","doi":"10.1016/j.jcin.2025.09.051","DOIUrl":"10.1016/j.jcin.2025.09.051","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Page 137"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes After Melody Transcatheter Pulmonary Valve Implant in Patients Weighing ≤30 kg","authors":"Elisa K. McCarthy MD ,&nbsp;Stanimir Georgiev MD ,&nbsp;Yulin Zhang PhD ,&nbsp;Matthew E. Boucek MD ,&nbsp;Kirby C. Johnson ,&nbsp;Ayush Jaggi MPH ,&nbsp;Daniel S. Levi MD ,&nbsp;Lynn F. Peng MD ,&nbsp;Mary Hunt Martin MD ,&nbsp;Brian H. Morray MD ,&nbsp;Athar M. Qureshi MD ,&nbsp;Alejandro J. Torres MD ,&nbsp;Allison K. Cabalka MD ,&nbsp;Holly Bauser-Heaton MD, PhD ,&nbsp;Felix Berger MD ,&nbsp;Peter Ewert MD ,&nbsp;Doff B. McElhinney MD","doi":"10.1016/j.jcin.2025.10.049","DOIUrl":"10.1016/j.jcin.2025.10.049","url":null,"abstract":"<div><h3>Background</h3><div>Small multicenter studies have shown that transcatheter pulmonary valve replacement (TPVR) can be performed with good procedural and early hemodynamic results in patients weighing &lt;30 kg; little is known about longer term outcomes.</div></div><div><h3>Objectives</h3><div>The aim of this study was to characterize long-term outcomes after Melody valve placement in patients weighing ≤30 kg.</div></div><div><h3>Methods</h3><div>Selected centers participating in prior registry studies provided updated outcome data.</div></div><div><h3>Results</h3><div>Between April 2009 and April 2019, 199 patients weighing ≤30kg underwent successful Melody valve placement across 10 centers. During a median follow-up period of nearly 8 years, 78 patients underwent initial reintervention with balloon dilation (n = 20), transcatheter valve-in-valve (n = 30), or explantation (n = 28). Among patients who had not undergone reintervention, 81% of those with available echocardiograms had good valve function. Thirty-two patients developed endocarditis, 20 with predisposing factors; 9 were managed medically. Estimated freedom from pulmonary valve reintervention at 10 years was 46% (95% CI: 36%-55%). On age- and weight-adjusted multivariable Cox regression, right ventricular systolic pressure immediately after implantation (HR: 1.03; 95% CI: 1.00-1.05; <em>P</em> = 0.026) was associated with freedom from reintervention. Freedom from Melody valve explantation at 10 years was 78% (95% CI: 69%-85%), and freedom from endocarditis was 79% (95% CI: 71%-86%). These outcomes did not vary significantly according to weight, delivery system, or era of implantation.</div></div><div><h3>Conclusions</h3><div>In this large multicenter study, longer term survival and freedom from reintervention or explantation after TPVR were similar to previously reported data for small patients with a surgical pulmonary conduit or bioprosthetic valve. These findings support the utility of TPVR with a Melody valve for delaying surgical valve replacement in small patients.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Pages 80-92"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conflict of Interest Among Journal Authors","authors":"Christopher J. White MD (Associate Editor, JACC: Cardiovascular Interventions)","doi":"10.1016/j.jcin.2025.10.048","DOIUrl":"10.1016/j.jcin.2025.10.048","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Pages 142-143"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Repeated Drug-Coated Balloon for Restenosis Following Femoropopliteal Drug-Coated Balloon Treatment","authors":"Yoshimitsu Soga MD, PhD ,&nbsp;Mitsuyoshi Takahara MD, PhD ,&nbsp;Osamu Iida MD, PhD ,&nbsp;Yusuke Tomoi MD ,&nbsp;Daizo Kawasaki MD, PhD ,&nbsp;Akiko Tanaka MD ,&nbsp;Yasutaka Yamauchi MD, PhD ,&nbsp;Kazuki Tobita MD ,&nbsp;Amane Kozuki MD, PhD ,&nbsp;Masahiko Fujihara MD ,&nbsp;OYSTER Investigators","doi":"10.1016/j.jcin.2025.10.043","DOIUrl":"10.1016/j.jcin.2025.10.043","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Pages 111-114"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mind the Gap!","authors":"Mara Pilati MD ,&nbsp;Fabiola Boccuto MD ,&nbsp;Claudia Montanaro MD ,&nbsp;Paolo Ciancarella MD ,&nbsp;Gianfranco Butera MD","doi":"10.1016/j.jcin.2025.10.061","DOIUrl":"10.1016/j.jcin.2025.10.061","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Pages 122-124"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Papillary Muscle Banding to Reshape Failing Left Ventricle","authors":"Piotr Musialek MD, DPhil ,&nbsp;Lukasz Tekieli MD, PhD ,&nbsp;Adam Mazurek MD, PhD ,&nbsp;Lukasz Czyz MD ,&nbsp;Jakub Chmiel MD ,&nbsp;Krzysztof Bartus MD, PhD ,&nbsp;R. Pawel Banys MSc (Eng) ,&nbsp;Joanna Szachowicz-Jaworska MD ,&nbsp;Jacek Piatek MD, PhD ,&nbsp;Andrzej Gackowski MD, PhD","doi":"10.1016/j.jcin.2025.10.047","DOIUrl":"10.1016/j.jcin.2025.10.047","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Pages 127-133"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stress Hyperglycemia Should Not Be Confused With Diabetes Mellitus","authors":"Hao Yang MM,&nbsp;Jieyi Wang MD,&nbsp;Aisong Zhu MD","doi":"10.1016/j.jcin.2025.04.052","DOIUrl":"10.1016/j.jcin.2025.04.052","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Page 139"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OCT-Guided Clues","authors":"Ioannis Skalidis MD, PhD,&nbsp;Thierry Unterseeh MD,&nbsp;Pietro Laforgia MD,&nbsp;Stephane Chapagne MD,&nbsp;Nicolas Amabile MD, PhD","doi":"10.1016/j.jcin.2025.05.048","DOIUrl":"10.1016/j.jcin.2025.05.048","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 1","pages":"Page 141"},"PeriodicalIF":11.4,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145950254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}