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Pilot Study of a Mobile, Virtual Reality-Based Digital Therapeutic for Smoking Cessation: Randomized Controlled Trial. 一种基于虚拟现实的移动数字戒烟疗法的初步研究:随机对照试验。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-12 DOI: 10.2196/66411
Yeong-Seon Jo, Arom Pyeon, Min-Kyung Hu, SungMin Kim, In-Young Choi, Dai-Jin Kim, Ji-Won Chun
<p><strong>Background: </strong>Smoking cessation remains a global challenge, with traditional treatments showing limited long-term success due to low adherence and accessibility issues. Digital therapeutics, such as mobile apps and virtual reality (VR)-based interventions, could offer innovative solutions for smoking cessation treatment. NICO-THERA is a digital therapeutic program integrating cognitive behavioral therapy (CBT) and motivational enhancement therapy (MET) to address nicotine dependence.</p><p><strong>Objective: </strong>This study aims to evaluate the safety and efficacy of NICO-THERA, a digital therapeutic intervention combining VR and mobile apps, for supporting smoking cessation among individuals with nicotine dependence. The primary focus was on smoking abstinence, nicotine dependence reduction, and motivation to quit smoking over a 12-week intervention period.</p><p><strong>Methods: </strong>This open-label, exploratory, randomized controlled trial involved 30 participants randomly assigned to the digital therapeutic group (DTG; n=15; mean age 43.1 years; mean number of daily cigarettes: 9.5) or basic treatment group (BTG; n=15; mean age 48.7 years; mean number of daily cigarettes: 9.2). The DTG received the NICO-THERA program, involving VR sessions (relaxation training, craving coping, and refusal skills) and mobile app-based CBT and MET modules for daily therapeutic exercises. The BTG received basic care including video education and printed materials. The primary outcomes were the 7-day point prevalence abstinence (PPA) and 30-day PPA at 8 weeks and 12 weeks. Secondary outcomes included nicotine dependence (Fagerström Test for Nicotine Dependence [FTND]) and motivation to change (Stages of Change Readiness and Treatment Eagerness Scale-Smoking [SOCRATES-S]).</p><p><strong>Results: </strong>There were no significant differences in 7-day and 30-day PPA between the DTG and BTG. However, in within-group analyses, the DTG showed significant improvements in both 7-day and 30-day PPA at week 8 (z=-2.00, P=.046), along with consistent reductions in smoking days and cigarette consumption across all time points. The BTG only significantly decreased cigarette consumption at week 8. Additionally, the DTG exhibited a significant increase in taking steps of motivation at week 12 (U=19.00, P=.048) compared with the BTG. No adverse device effects were reported. Adherence to smoking cessation diaries and medication logs was higher in the DTG (mean 83 of 84 days, 99%; 9 participants) than in the BTG (mean 74 of 84 days, 88%; 12 participants), based on the 12-week average adherence among those who completed the study.</p><p><strong>Conclusions: </strong>The NICO-THERA digital therapeutic program demonstrated preliminary effectiveness at reducing nicotine dependence. Additionally, participants in the DTG group exhibited a progressive improvement in their motivation to quit smoking, as reflected by a significant reduction in ambivalence at week
背景:戒烟仍然是一个全球性的挑战,由于低依从性和可及性问题,传统的治疗方法显示有限的长期成功。数字疗法,如移动应用程序和基于虚拟现实(VR)的干预措施,可以为戒烟治疗提供创新的解决方案。NICO-THERA是一个整合认知行为疗法(CBT)和动机增强疗法(MET)的数字治疗项目,旨在解决尼古丁依赖问题。目的:本研究旨在评估NICO-THERA的安全性和有效性,NICO-THERA是一种结合VR和移动应用程序的数字治疗干预,用于支持尼古丁依赖者戒烟。在为期12周的干预期内,主要关注戒烟、减少尼古丁依赖和戒烟动机。方法:本开放标签、探索性、随机对照试验纳入30例受试者,随机分为数字治疗组(DTG, n=15,平均年龄43.1岁,平均每日吸烟9.5支)和基础治疗组(BTG, n=15,平均年龄48.7岁,平均每日吸烟9.2支)。DTG接受NICO-THERA项目,包括VR会话(放松训练、渴望应对和拒绝技能)和基于移动应用程序的CBT和MET模块的日常治疗练习。BTG得到了包括视频教育和印刷材料在内的基本照顾。主要结果是在8周和12周时的7天点流行戒断(PPA)和30天PPA。次要结局包括尼古丁依赖(Fagerström尼古丁依赖测试[FTND])和改变动机(改变准备阶段和治疗渴望量表-吸烟[SOCRATES-S])。结果:DTG组与BTG组7天、30天PPA差异无统计学意义。然而,在组内分析中,DTG在第8周的7天和30天PPA均显示出显着改善(z=-2.00, P= 0.046),同时在所有时间点吸烟天数和卷烟消费量均一致减少。BTG仅在第8周显著减少香烟消费量。此外,与BTG相比,DTG在第12周表现出动机步骤的显著增加(U=19.00, P= 0.048)。无不良器械效应报告。根据完成研究的参与者的12周平均依从性,DTG组(84天中平均83天,99%;9名参与者)比BTG组(84天中平均74天,88%;12名参与者)更坚持戒烟日记和服药日志。结论:NICO-THERA数字治疗程序在减少尼古丁依赖方面显示出初步的有效性。此外,DTG组的参与者在戒烟动机方面表现出了渐进式的改善,这反映在第8周矛盾心理的显著减少和第12周主动戒烟努力的增加。这些结果表明,NICO-THERA项目中MET和CBT的结构化整合有效地增强了戒烟的心理准备,促进了对行为改变的持续承诺。试验注册:韩国临床研究信息服务中心KCT0009801;https://cris.nih.go.kr/cris/search/detailSearch.do?seq=28285&status=5&seq_group=28285&search_page=M。
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引用次数: 0
Effects of a Transtheoretical Model-Based mHealth Intervention on Transition Readiness in Adolescents With Epilepsy: Quasi-Experimental Study. 基于跨理论模型的移动健康干预对青少年癫痫患者过渡准备的影响:准实验研究
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-11 DOI: 10.2196/70085
Qing Xia, Shuangzi Li, Ting Wang, Mingping Fan, Jie Xia, Lingling Xie, Huaying Yin
<p><strong>Background: </strong>Enhancing self-management and transition readiness in adolescents with epilepsy is essential for successful transition to adult care. The combination of the transtheoretical model (TTM) and mobile health (mHealth) management provides a framework for reducing intervention costs while personalizing care.</p><p><strong>Objective: </strong>This quasi-experimental study evaluates the feasibility of TTM-based mHealth management for improving transition services in adolescents with epilepsy.</p><p><strong>Methods: </strong>A total of 98 adolescent patients with epilepsy aged 12-18 years were recruited. Using a nonrandomized design based on treatment locations, they were allocated into either the intervention group (n=49) or the control group (n=49). The intervention group received a TTM-based mHealth management program, which included phase-specific group sessions led by a multidisciplinary team and conducted via Tencent Meeting every 2 weeks or monthly (biweekly for the precontemplation, contemplation, and preparation, and monthly for the action and maintenance). The sessions involved lectures, discussions, and a mini-program that provided disease management support, motivational strategies, and digital reminders tailored to each stage. The control group received conventional remote extended care, consisting of biweekly group lectures and discussions for all patients and their families via Tencent Meeting, supplemented by regular health education materials delivered through a WeChat group. Telephone follow-ups were conducted at the third and sixth months. The total intervention duration was 6 months for both groups. Outcomes were assessed after 6 months using the self-management stage, Self-Management and Transition to Adulthood with Rx=Treatment questionnaire, and a self-developed program acceptability questionnaire.</p><p><strong>Results: </strong>Postintervention, the intervention group demonstrated significantly better self-management behavior stages compared with controls. At the end of 6 months of intervention, the majority of participants in the intervention group reached the action stage (16/49, 32.65%) and maintenance stage (14/49, 28.57%), whereas most controls remained in precontemplation (12/49, 24.49%) and contemplation stages (13/49, 26.53%). Both groups showed significant improvements from baseline in medication management, health care participation, disease knowledge, doctor-patient communication, and transition readiness total scores at 6-month follow-up (all P<.05). Notably, the intervention group achieved additional incremental benefits versus controls (medication management: 3.81, 95% CI 1.26-6.36; health care engagement: 2.77, 95% CI 0.52-5.02; disease knowledge: 1.30, 95% CI 0.28-2.31; provider communication: 3.42, 95% CI 1.62-5.22; transition readiness: 11.30, 95% CI 5.70-6.89; effect sizes [Cohen d] ranged from 0.527 to 0.864, indicating moderate-to-large clinical effects). The overall satisfactio
背景:加强青少年癫痫患者的自我管理和过渡准备对于成功过渡到成人护理至关重要。跨理论模型(TTM)和移动医疗(mHealth)管理的结合提供了一个框架,可以在个性化护理的同时降低干预成本。目的:本准实验研究评估基于ttm的移动健康管理改善青少年癫痫患者过渡服务的可行性。方法:选取年龄12 ~ 18岁的青少年癫痫患者98例。采用基于治疗地点的非随机设计,将他们分为干预组(n=49)和对照组(n=49)。干预组接受基于ttm的移动健康管理计划,其中包括由多学科团队领导的特定阶段小组会议,每两周或每月通过腾讯会议进行一次(每两周进行一次预演,沉思和准备,每月进行一次行动和维护)。会议包括讲座、讨论和一个小程序,该程序提供疾病管理支持、激励策略和针对每个阶段量身定制的数字提醒。对照组接受常规远程延伸护理,包括每两周通过腾讯会议对所有患者和家属进行小组讲座和讨论,并通过微信小组定期提供健康教育资料。在第三个月和第六个月进行了电话随访。两组总干预时间均为6个月。6个月后,使用自我管理阶段、自我管理和成年过渡期Rx=治疗问卷以及自行开发的项目可接受性问卷对结果进行评估。结果:干预后,干预组自我管理行为阶段明显优于对照组。干预6个月结束时,干预组大多数参与者进入行动阶段(16/49,32.65%)和维持阶段(14/49,28.57%),而对照组大多数仍处于预思考阶段(12/49,24.49%)和沉思阶段(13/49,26.53%)。在6个月的随访中,两组在药物管理、医疗保健参与、疾病知识、医患沟通和过渡准备总分方面均较基线有显著改善。结论:基于ttm的移动健康管理项目可以有效改善青少年癫痫患者的自我管理行为改变,增强过渡准备,从而促进青少年癫痫患者顺利过渡到成人医疗保健。该方案具有较高的可接受性,可为建立临床过渡服务方案提供参考。然而,本研究为单中心、准实验试验,样本量小,干预时间短。这些发现需要通过更大规模的随机对照试验来证实其有效性。
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引用次数: 0
Leveraging Social Media and Crowdsourcing to Recruit and Retain Military Veterans With Posttraumatic Stress Disorder or Experience of Harmful Gambling for mHealth Interventions: Descriptive Study. 利用社交媒体和众包招募和留住有创伤后应激障碍或有害赌博经历的退伍军人进行移动健康干预:描述性研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-11 DOI: 10.2196/73706
Conor Heath, Jess M Williams, Daniel Leightley, Dominic Murphy, Simon Dymond

Background: Military veterans may be at increased risk of posttraumatic stress disorder (PTSD) compared to the general population. PTSD is often comorbid with harmful and problematic patterns of gambling. Behavioral therapies such as acceptance and commitment therapy have shown promise in treating these co-occurring disorders, especially if combined with mobile health (mHealth) interventions to circumvent known help-seeking barriers faced by veterans. However, to date, recruitment for mHealth interventions has been challenging and may impact intervention feasibility.

Objective: In this paper, our objectives were to describe the strategies used to recruit UK military veterans with PTSD or experience of harmful gambling to a pilot study of a smartphone-based digital intervention, ACT Vet.

Methods: We used several recruitment strategies, such as direct mailing, paid study advertising on social media (Facebook) and an online research platform (Prolific), study-specific website management, in-person event hosting with veterans' charities, snowball sampling, and incentives for completion.

Results: Results showed that, over 27 days, recruitment through Facebook accounted for 21 eligible veterans (n=7, 33% through unpaid advertising and n=14, 67% through paid advertising), whereas Prolific accounted for 50 veterans. Additional strategies recruited 8 eligible veterans. In total, 79 eligible military veterans were recruited for ACT Vet, with 24 (30%) completing the final steps of the study.

Conclusions: Difficulties such as low advertisement conversion rate and participant and data attrition arose throughout this study. Our findings illustrate the relative effectiveness of social media- and online platform-based initiatives in recruiting veterans with PTSD or harmful gambling. Future research should consider establishing an online presence for effective digital intervention recruitment with diverse branding to attract representative samples of veterans for mHealth research.

背景:与普通人群相比,退伍军人患创伤后应激障碍(PTSD)的风险可能更高。创伤后应激障碍通常与有害和有问题的赌博模式并存。接受和承诺疗法等行为疗法在治疗这些共同发生的疾病方面显示出希望,特别是如果与移动健康(mHealth)干预措施相结合,以规避退伍军人面临的已知寻求帮助障碍。然而,迄今为止,移动医疗干预措施的招聘一直具有挑战性,并可能影响干预措施的可行性。目的:在本文中,我们的目标是描述用于招募患有创伤后应激障碍或有有害赌博经历的英国退伍军人的策略,以进行基于智能手机的数字干预ACT Vet的试点研究。方法:我们采用了几种招聘策略,如直接邮寄、在社交媒体(Facebook)和在线研究平台(高产)上进行付费研究广告、针对研究的网站管理、与退伍军人慈善机构共同举办现场活动、滚雪球抽样和完成奖励。结果显示,在27天的时间里,通过Facebook招募的退伍军人人数为21人(n= 7.33%通过免费广告招募,n= 14.67%通过付费广告招募),而通过多产渠道招募的退伍军人人数为50人。其他策略招募了8名符合条件的退伍军人。总共招募了79名符合条件的退伍军人参加ACT Vet,其中24人(30%)完成了研究的最后步骤。结论:在整个研究过程中,出现了广告转化率低、参与者和数据流失等问题。我们的研究结果说明了基于社交媒体和在线平台的举措在招募患有创伤后应激障碍或有害赌博的退伍军人方面的相对有效性。未来的研究应该考虑建立一个有效的数字干预招聘的在线存在,以不同的品牌吸引有代表性的退伍军人样本进行移动健康研究。
{"title":"Leveraging Social Media and Crowdsourcing to Recruit and Retain Military Veterans With Posttraumatic Stress Disorder or Experience of Harmful Gambling for mHealth Interventions: Descriptive Study.","authors":"Conor Heath, Jess M Williams, Daniel Leightley, Dominic Murphy, Simon Dymond","doi":"10.2196/73706","DOIUrl":"10.2196/73706","url":null,"abstract":"<p><strong>Background: </strong>Military veterans may be at increased risk of posttraumatic stress disorder (PTSD) compared to the general population. PTSD is often comorbid with harmful and problematic patterns of gambling. Behavioral therapies such as acceptance and commitment therapy have shown promise in treating these co-occurring disorders, especially if combined with mobile health (mHealth) interventions to circumvent known help-seeking barriers faced by veterans. However, to date, recruitment for mHealth interventions has been challenging and may impact intervention feasibility.</p><p><strong>Objective: </strong>In this paper, our objectives were to describe the strategies used to recruit UK military veterans with PTSD or experience of harmful gambling to a pilot study of a smartphone-based digital intervention, ACT Vet.</p><p><strong>Methods: </strong>We used several recruitment strategies, such as direct mailing, paid study advertising on social media (Facebook) and an online research platform (Prolific), study-specific website management, in-person event hosting with veterans' charities, snowball sampling, and incentives for completion.</p><p><strong>Results: </strong>Results showed that, over 27 days, recruitment through Facebook accounted for 21 eligible veterans (n=7, 33% through unpaid advertising and n=14, 67% through paid advertising), whereas Prolific accounted for 50 veterans. Additional strategies recruited 8 eligible veterans. In total, 79 eligible military veterans were recruited for ACT Vet, with 24 (30%) completing the final steps of the study.</p><p><strong>Conclusions: </strong>Difficulties such as low advertisement conversion rate and participant and data attrition arose throughout this study. Our findings illustrate the relative effectiveness of social media- and online platform-based initiatives in recruiting veterans with PTSD or harmful gambling. Future research should consider establishing an online presence for effective digital intervention recruitment with diverse branding to attract representative samples of veterans for mHealth research.</p>","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e73706"},"PeriodicalIF":6.2,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12604826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145495504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AI-Driven Real-Time Monitoring of Cardiovascular Conditions With Wearable Devices: Scoping Review. 人工智能驱动的心血管疾病实时监测与可穿戴设备:范围审查。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-11 DOI: 10.2196/73846
Ali Abedi, Anshul Verma, Dherya Jain, Jathushan Kaetheeswaran, Cynthia Chui, Milad Lankarany, Shehroz S Khan
<p><strong>Background: </strong>Cardiovascular diseases remain the leading cause of mortality worldwide, accounting for 18 million deaths annually. Detection and prediction of cardiovascular conditions are essential for timely intervention and improved patient outcomes. Wearable devices offer a promising, noninvasive solution for continuous monitoring of cardiovascular signals, vital signs, and physical activity. However, the large data volumes generated by these devices and the rapid fluctuations in cardiovascular signals necessitate advanced artificial intelligence (AI) techniques for real-time analysis and effective clinical decision-making.</p><p><strong>Objective: </strong>The objective of this scoping review was to identify the main challenges of AI-driven platforms for real-time cardiovascular condition monitoring with wearable devices and explore potential solutions. In addition, this review aimed to examine how AI algorithms are developed for robust monitoring and how deployment pipelines are optimized to enable real-time cardiovascular condition monitoring.</p><p><strong>Methods: </strong>A comprehensive search was conducted in the following electronic databases: MEDLINE(R) ALL (Ovid), Embase (Ovid), Cochrane Central Register of Controlled Trials (Ovid), Web of Science Core Collection (Clarivate), IEEE Xplore, and ACM Digital Library, yielding 2385 unique records. Inclusion criteria focused on studies that used wearable devices for participant data collection and applied AI algorithms for real-time analysis to detect or predict cardiovascular events and diseases. After title and abstract screening, 153 papers remained, and following a full-text review, 19 studies met the inclusion criteria.</p><p><strong>Results: </strong>The findings indicate that despite the promise of AI and wearable devices, research on real-time cardiovascular monitoring remains limited and lacks comprehensive validation. Most studies relied on publicly available wearable datasets rather than real-world validation with recruited participants in community settings. Studies that deployed AI algorithms in real time frequently failed to report operational characteristics and challenges. Electrocardiography-based wearable sensors were the most frequently used devices, primarily in hospital settings. A variety of AI techniques, ranging from traditional machine learning to lightweight deep learning algorithms, were deployed either on wearable devices or via cloud-based processing.</p><p><strong>Conclusions: </strong>Robust, interdisciplinary research is needed to harness the full potential of AI-driven, real-time cardiovascular health management using wearable devices. This includes the development and validation of scalable solutions for continuous community-based deployment. Furthermore, real-world challenges such as participant compliance, hardware and connectivity constraints, and AI model optimization for real-time continuous monitoring must be carefully addressed.</
背景:心血管疾病仍然是全世界死亡的主要原因,每年造成1800万人死亡。检测和预测心血管疾病对于及时干预和改善患者预后至关重要。可穿戴设备为持续监测心血管信号、生命体征和身体活动提供了一种有前途的、无创的解决方案。然而,这些设备产生的大数据量和心血管信号的快速波动需要先进的人工智能(AI)技术进行实时分析和有效的临床决策。目的:本综述的目的是确定人工智能驱动的可穿戴设备实时心血管状况监测平台的主要挑战,并探索潜在的解决方案。此外,本综述旨在研究如何开发用于鲁棒监测的人工智能算法,以及如何优化部署管道以实现实时心血管状况监测。方法:在MEDLINE(R) ALL (Ovid)、Embase (Ovid)、Cochrane Central Register of Controlled Trials (Ovid)、Web of Science Core Collection (Clarivate)、IEEE Xplore和ACM Digital Library等电子数据库中进行全面检索,得到2385条唯一记录。纳入标准侧重于使用可穿戴设备收集参与者数据并应用人工智能算法进行实时分析以检测或预测心血管事件和疾病的研究。在标题和摘要筛选后,153篇论文被保留下来,在全文审查后,19项研究符合纳入标准。结果:研究结果表明,尽管人工智能和可穿戴设备前景广阔,但对实时心血管监测的研究仍然有限,缺乏全面的验证。大多数研究依赖于公开可用的可穿戴数据集,而不是在社区环境中招募参与者进行真实验证。实时部署人工智能算法的研究经常无法报告操作特征和挑战。基于心电图的可穿戴传感器是最常用的设备,主要用于医院环境。各种各样的人工智能技术,从传统的机器学习到轻量级的深度学习算法,要么部署在可穿戴设备上,要么通过基于云的处理。结论:需要进行强有力的跨学科研究,以利用可穿戴设备充分利用人工智能驱动的实时心血管健康管理的潜力。这包括为持续的基于社区的部署开发和验证可伸缩的解决方案。此外,现实世界的挑战,如参与者的合规性、硬件和连接限制,以及实时连续监测的人工智能模型优化,必须仔细解决。
{"title":"AI-Driven Real-Time Monitoring of Cardiovascular Conditions With Wearable Devices: Scoping Review.","authors":"Ali Abedi, Anshul Verma, Dherya Jain, Jathushan Kaetheeswaran, Cynthia Chui, Milad Lankarany, Shehroz S Khan","doi":"10.2196/73846","DOIUrl":"10.2196/73846","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Cardiovascular diseases remain the leading cause of mortality worldwide, accounting for 18 million deaths annually. Detection and prediction of cardiovascular conditions are essential for timely intervention and improved patient outcomes. Wearable devices offer a promising, noninvasive solution for continuous monitoring of cardiovascular signals, vital signs, and physical activity. However, the large data volumes generated by these devices and the rapid fluctuations in cardiovascular signals necessitate advanced artificial intelligence (AI) techniques for real-time analysis and effective clinical decision-making.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;The objective of this scoping review was to identify the main challenges of AI-driven platforms for real-time cardiovascular condition monitoring with wearable devices and explore potential solutions. In addition, this review aimed to examine how AI algorithms are developed for robust monitoring and how deployment pipelines are optimized to enable real-time cardiovascular condition monitoring.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A comprehensive search was conducted in the following electronic databases: MEDLINE(R) ALL (Ovid), Embase (Ovid), Cochrane Central Register of Controlled Trials (Ovid), Web of Science Core Collection (Clarivate), IEEE Xplore, and ACM Digital Library, yielding 2385 unique records. Inclusion criteria focused on studies that used wearable devices for participant data collection and applied AI algorithms for real-time analysis to detect or predict cardiovascular events and diseases. After title and abstract screening, 153 papers remained, and following a full-text review, 19 studies met the inclusion criteria.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The findings indicate that despite the promise of AI and wearable devices, research on real-time cardiovascular monitoring remains limited and lacks comprehensive validation. Most studies relied on publicly available wearable datasets rather than real-world validation with recruited participants in community settings. Studies that deployed AI algorithms in real time frequently failed to report operational characteristics and challenges. Electrocardiography-based wearable sensors were the most frequently used devices, primarily in hospital settings. A variety of AI techniques, ranging from traditional machine learning to lightweight deep learning algorithms, were deployed either on wearable devices or via cloud-based processing.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Robust, interdisciplinary research is needed to harness the full potential of AI-driven, real-time cardiovascular health management using wearable devices. This includes the development and validation of scalable solutions for continuous community-based deployment. Furthermore, real-world challenges such as participant compliance, hardware and connectivity constraints, and AI model optimization for real-time continuous monitoring must be carefully addressed.&lt;/","PeriodicalId":14756,"journal":{"name":"JMIR mHealth and uHealth","volume":"13 ","pages":"e73846"},"PeriodicalIF":6.2,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12777649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145495387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
User Experience in mHealth Research: Bibliometric Analysis of Trends and Developments (2007-2023). 移动医疗研究中的用户体验:趋势和发展的文献计量学分析(2007-2023)。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-10 DOI: 10.2196/75909
Bashaer Alkhwaiter, Monira Aloud, Nora Almezeini
<p><strong>Background: </strong>The significance of mobile health (mHealth) apps transforms traditional health care delivery and enables individuals to actively manage their health. The success and effectiveness of mHealth apps heavily depend on the user experience and satisfaction. Previous studies have examined mHealth adoption through systematic literature reviews, focusing on mental health, chronic disease management, fitness, and public health responses to crises like the COVID-19 pandemic. However, the state of research, the key trends, themes, and gaps in the user experience and satisfaction with mHealth apps remain unexplored.</p><p><strong>Objective: </strong>This study aimed to investigate the state of research on user experience in mHealth apps through a bibliometric analysis. Furthermore, the study aims to systematically identify research trends and themes by extending the analysis of the science mapping technique, co-word analysis, and bibliographic coupling.</p><p><strong>Methods: </strong>The bibliographic data corpus was collected from Scopus and Web of Science and systematically analyzed using bibliometric performance analysis and science mapping techniques. The methodology incorporates various data processing and visualization tools, including VOS Viewer, OriginLab, and SiteSpace. Then, a comprehensive review metric, combining the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework and a 4-step approach from data collection to interpretation is used.</p><p><strong>Results: </strong>The bibliographic analysis spans 16 years and includes 814 unique publications authored by 4870 researchers from 81 countries and 1948 organizations, published across 351 high-impact journals and prominent conferences. The analysis of research trends identifies 2 key trends: the differentiation in keyword usage for user experience and user satisfaction, and the research methodologies used within the domain. Furthermore, 5 research themes were identified exploring critical aspects of technology use, user engagement, and clinical integration. Although all 5 themes overlap, each theme focuses on distinct elements that help delineate their contributions to the overall understanding of mHealth apps: technological evaluation (Theme 1), design features for engagement (Theme 2), patient usability (Theme 3), long-term engagement factors (Theme 4), and clinical integration (Theme 5).</p><p><strong>Conclusions: </strong>This study offers a fundamental understanding of the bibliographic landscape of research on user experience and satisfaction with mHealth apps. By identifying major research clusters, influential works, and emerging topics, this analysis provides evidence-based guidance for researchers, developers, and health informatics practitioners. Furthermore, based on the research trends findings, future research should prioritize expanding the scope of user experience (UX) evaluation by incorporating diverse user populatio
背景:移动医疗(mHealth)应用程序的意义改变了传统的医疗保健服务,使个人能够主动管理自己的健康。移动健康应用程序的成功和有效性在很大程度上取决于用户体验和满意度。之前的研究通过系统的文献综述考察了移动医疗的采用情况,重点关注心理健康、慢性疾病管理、健身和对COVID-19大流行等危机的公共卫生反应。然而,研究现状、主要趋势、主题以及用户体验和移动健康应用满意度方面的差距仍未得到探索。目的:本研究旨在通过文献计量学分析调查移动健康应用程序中用户体验的研究现状。在此基础上,通过对科学制图技术、共词分析和书目耦合的扩展分析,系统地识别研究趋势和主题。方法:采用文献计量学绩效分析和科学制图技术对Scopus和Web of Science的文献数据语料库进行系统分析。该方法结合了各种数据处理和可视化工具,包括VOS Viewer、OriginLab和SiteSpace。然后,使用综合评价指标,结合PRISMA(系统评价和荟萃分析的首选报告项目)框架和从数据收集到解释的四步方法。结果:文献分析跨越16年,包括来自81个国家和1948个组织的4870名研究人员撰写的814篇独特出版物,发表在351个高影响力期刊和著名会议上。对研究趋势的分析确定了两个关键趋势:用户体验和用户满意度关键字使用的差异,以及领域内使用的研究方法。此外,确定了5个研究主题,探索技术使用、用户参与和临床整合的关键方面。虽然所有5个主题重叠,但每个主题都侧重于不同的元素,这些元素有助于描述它们对移动健康应用程序的整体理解:技术评估(主题1)、参与设计功能(主题2)、患者可用性(主题3)、长期参与因素(主题4)和临床整合(主题5)。结论:本研究提供了对移动健康应用程序用户体验和满意度研究的文献景观的基本理解。通过确定主要的研究集群、有影响力的作品和新兴主题,本分析为研究人员、开发人员和卫生信息学从业者提供了基于证据的指导。此外,根据研究趋势发现,未来的研究应优先考虑扩大用户体验(UX)评估的范围,包括不同的用户群体、纵向研究以及人工智能和个性化干预等新兴技术。整合跨学科视角的见解,如人机交互、行为科学和医疗保健信息学,可以增强对用户需求和应用程序有效性的理解。还建议使用更标准化的框架来评估移动健康应用程序中的用户体验,以促进研究之间的可比性,并改进应用程序设计,以最大限度地提高用户参与度和健康结果。
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引用次数: 0
Calorie Counting Apps for Monitoring and Managing Calorie Intake in Adults living with Weight-Related Chronic Diseases: A Decade-long Scoping Review (2013-2024). 用于监测和管理患有体重相关慢性疾病的成人卡路里摄入的卡路里计数应用程序:长达十年的范围审查(2013-2024)。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-07 DOI: 10.2196/64139
Kaylee Rose Dugas, Marie-Andrée Giroux, Abdelatif Guerroudj, Jazna Leger, Asal Rouhafzay, Ghazal Rouhafzay, Jalila Jbilou
<p><strong>Background: </strong>Overweight and obesity, as defined by the World Health Organization, correspond to body mass index (BMI) values of 25.0-29.9 kg/m² for overweight and ≥ 30 kg/m² for obesity. Both conditions remain major public health challenges worldwide due to their strong link with type 2 diabetes, cardiovascular disease, and hypertension, which place a heavy clinical and economic burden on healthcare systems. In Canada, obesity rates are notably high, with vulnerable populations disproportionately affected due to socioeconomic barriers, limited access to preventive care, and higher comorbidity rates. Mobile health (mHealth) technologies, particularly calorie-counting apps, have emerged as promising tools for dietary self-monitoring and weight control. However, their heterogeneity in design and evidence base complicates the evaluation of their clinical feasibility and real-world effectiveness.</p><p><strong>Objective: </strong>This study systematically evaluated the structure and content of 46 calorie-counting apps, identify factors of their acceptability and feasibility among adults living with obesity or weight-related chronic diseases, and formulate evidence-based recommendations for app developers, clinicians, and researchers.</p><p><strong>Methods: </strong>We conducted a scoping review of the literature on calorie counting apps published between January 2013 and March 2024. A total of 771 records were identified and, after following PRISMA-ScR guidance, sixty-eight studies met the inclusion criteria. Data were extracted on app functionalities, features, and user engagement metrics, as well as factors influencing app acceptability and feasibility among adults living with overweight or weight-related chronic conditions. The findings were synthesized to provide practical recommendations for the design and clinical implementation of calorie counting apps.</p><p><strong>Results: </strong>Sixty-eight studies met the inclusion criteria and were included in the analysis. Randomized controlled trials (34.0%) and cohort studies (24.0%) were the most common designs. Most studies targeted adults with overweight or obesity (78.0%), while diabetes and hypertension were less frequently represented. In total, forty-six distinct calorie counting apps were identified, with MyFitnessPal and Lose It! being the most frequently studied. Nearly all apps (98.0%) offered calorie logging, often through manual entry supported by food databases, and about half included goal-setting features. Factors of acceptability most often cited were personalization, automated functionalities, user-friendly design, and data sharing with healthcare professionals, while barriers included technical issues, limited food databases, and the time burden of manual entry. Adherence declined over time. For example, self-monitoring with MyFitnessPal decreased from 5.4 days/week at 4 weeks to 1.4 days/week at 12 weeks, while daily use of Lose It! dropped to 4 days/week by the
背景:根据世界卫生组织的定义,超重和肥胖对应于体重指数(BMI)值,超重为25.0-29.9 kg/m²,肥胖为≥30 kg/m²。由于这两种疾病与2型糖尿病、心血管疾病和高血压密切相关,给卫生保健系统带来了沉重的临床和经济负担,因此仍是全球主要的公共卫生挑战。在加拿大,肥胖率非常高,由于社会经济障碍、获得预防保健的机会有限以及较高的合并症率,弱势群体受到了不成比例的影响。移动健康(mHealth)技术,特别是卡路里计算应用程序,已经成为饮食自我监测和体重控制的有前途的工具。然而,它们在设计和证据基础上的异质性使其临床可行性和实际有效性的评估复杂化。目的:本研究系统评估了46款卡路里计数app的结构和内容,确定其在肥胖或体重相关慢性疾病成年人中的可接受性和可行性因素,并为app开发者、临床医生和研究人员制定基于证据的建议。方法:我们对2013年1月至2024年3月期间发布的卡路里计算应用程序的文献进行了范围审查。在遵循PRISMA-ScR指南后,共确定了771份记录,其中68项研究符合纳入标准。数据提取了应用程序的功能、特性和用户参与度指标,以及影响超重或体重相关慢性疾病成年人应用程序可接受性和可行性的因素。这些研究结果被综合起来,为卡路里计算应用程序的设计和临床应用提供实用建议。结果:68项研究符合纳入标准并被纳入分析。随机对照试验(34.0%)和队列研究(24.0%)是最常见的设计。大多数研究针对超重或肥胖的成年人(78.0%),而糖尿病和高血压的研究较少。总共确定了46个不同的卡路里计算应用程序,包括MyFitnessPal和Lose It!最常被研究的。几乎所有的应用程序(98.0%)都提供卡路里记录,通常是通过食物数据库支持的手动输入,大约一半的应用程序包含目标设定功能。最常被引用的可接受性因素是个性化、自动化功能、用户友好设计和与医疗保健专业人员共享数据,而障碍包括技术问题、有限的食品数据库和手动输入的时间负担。依从性随着时间的推移而下降。例如,使用MyFitnessPal进行自我监测,从第4周的5.4天/周减少到第12周的1.4天/周,而每天使用Lose It!12周后降至每周4天。总共提出了12项建议,以提高患有体重相关慢性疾病的人使用卡路里计算应用程序的可行性和可接受性。结论:卡路里计算应用程序有潜力成为支持肥胖和体重相关慢性疾病患者的工具。为了增强其临床效用,应用程序开发人员应该专注于通过个性化和自动化功能来提高用户参与度,确保全面的食物数据库,并最大限度地减少饮食自我监测所需的工作量。需要进一步的研究来验证这些应用程序的有效性,并探索维持用户依从性的策略。这些发现为开发更有效和用户友好的移动医疗干预措施提供了有价值的见解。临床试验:
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引用次数: 0
Cluster-Based Predictive Modeling of User Ratings for Physical Activity Apps Using Mobile App Rating Scale (MARS) Dimensions: Model Development and Validation. 使用移动应用评级量表(MARS)维度的基于聚类的体育活动应用用户评级预测建模:模型开发与验证。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-06 DOI: 10.2196/70987
Ayush Bhattacharya, Jose Fernando Florez-Arango

Background: The expansion of mobile health app or apps has created a growing need for structured and predictive tools to evaluate app quality before deployment. The Mobile App Rating Scale (MARS) offers a standardized, expert-driven assessment across 4 key dimensions-engagement, functionality, aesthetics, and information-but its use in forecasting user satisfaction through predictive modeling remains limited.

Objective: This study aimed to investigate how k-means clustering, combined with machine learning models, can predict user ratings for physical activity apps based on MARS dimensions, with the goal of forecasting ratings before production and uncovering insights into user satisfaction drivers.

Methods: We analyzed a dataset of 155 MARS-rated physical activity apps with user ratings. The dataset was split into training (n=111) and testing (n=44) subsets. K means clustering was applied to the training data, identifying 2 clusters. Exploratory data analysis included box plots, summary statistics, and component+residual plots to visualize linearity and distribution patterns across MARS dimensions. Correlation analysis was performed to quantify relationships between each MARS dimension and user ratings. In total, 5 machine learning models-generalized additive models, k-nearest neighbors, random forest, extreme gradient boosting, and support vector regression-were trained with and without clustering. Models were hypertuned and trained separately on each cluster, and the best-performing model for each cluster was selected. These predictions were combined to compute final performance metrics for the test set. Performance was evaluated using correct prediction percentage (0.5 range), mean absolute error, and R². Validation was performed on 2 additional datasets: mindfulness (n=85) and older adults (n=55) apps.

Results: Exploratory data analysis revealed that apps in cluster 1 were feature-rich and scored higher across all MARS dimensions, reflecting comprehensive and engagement-oriented designs. In contrast, cluster 2 comprised simpler, utilitarian apps focused on basic functionality. Component+residual plots showed nonlinear relationships, which became more interpretable within clusters. Correlation analysis indicated stronger associations between user ratings and engagement and functionality, but weaker or negative correlations with aesthetics and information, particularly in cluster 2. In the unclustered dataset, k nearest neighbors achieved 79.55% accuracy, mean absolute error=0.26, and R²=0.06. The combined support vector regression (cluster 1)+k-nearest neighbors (cluster 2) model achieved the highest performance: 88.64% accuracy, mean absolute error=0.27, and R²=0.04. Clustering improved prediction accuracy and enhanced alignment between predicted and actual user ratings. Models also generalized well to the external datasets.

Conclusions:

背景:随着移动健康应用的不断扩展,人们越来越需要结构化和预测性工具来评估应用的质量。移动应用评级量表(MARS)提供了一个标准化的、专家驱动的评估,涉及4个关键维度——参与度、功能、美学和信息——但它在通过预测建模预测用户满意度方面的应用仍然有限。目的:本研究旨在探讨k-means聚类结合机器学习模型如何基于MARS维度预测体育活动应用的用户评分,目的是在生产前预测评分,并揭示用户满意度驱动因素的见解。方法:我们分析了155个带有用户评分的mars评级体育活动应用程序的数据集。数据集被分成训练子集(n=111)和测试子集(n=44)。对训练数据进行K均值聚类,识别出2个聚类。探索性数据分析包括箱形图、汇总统计和成分+残差图,以可视化火星各维度的线性和分布模式。进行相关分析以量化每个MARS维度与用户评分之间的关系。总共有5个机器学习模型——广义加性模型、k近邻、随机森林、极端梯度增强和支持向量回归——在聚类和不聚类的情况下进行了训练。在每个聚类上分别对模型进行超调和训练,并为每个聚类选择性能最好的模型。将这些预测组合起来计算测试集的最终性能指标。使用正确的预测百分比(0.5范围)、平均绝对误差和R²来评估性能。在另外两个数据集上进行验证:正念(n=85)和老年人(n=55)应用程序。结果:探索性数据分析显示,集群1中的应用程序功能丰富,在所有MARS维度上得分更高,反映了全面和参与性导向的设计。相比之下,集群2包含更简单、实用的应用程序,专注于基本功能。分量+残差图呈现非线性关系,在聚类内更具可解释性。相关性分析表明,用户评分与用户粘性和功能之间存在更强的关联,但与美学和信息之间的相关性较弱或呈负相关,尤其是在集群2中。在未聚类的数据集中,k个最近邻的准确率达到79.55%,平均绝对误差=0.26,R²=0.06。组合支持向量回归(聚类1)+k近邻(聚类2)模型的准确率最高,达到88.64%,平均绝对误差为0.27,R²=0.04。聚类提高了预测的准确性,并增强了预测和实际用户评分之间的一致性。模型也可以很好地推广到外部数据集。结论:聚类和建模相结合的方法提高了预测的准确性,并揭示了用户满意度驱动因素在不同应用类型之间的差异。通过将MARS从描述性工具转变为预测性框架,本研究提供了一种可扩展的、透明的方法来预测应用程序开发过程中的用户评级,这在早期阶段或低数据设置中特别有用。
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引用次数: 0
The Effectiveness of an Artificial Intelligence-Based Gamified Intervention for Improving Maternal Health Outcomes Among Refugees and Underserved Women in Lebanon: Community Interventional Trial. 基于人工智能的游戏化干预对改善黎巴嫩难民和服务不足妇女孕产妇健康结果的有效性:社区干预试验。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-04 DOI: 10.2196/65599
Shadi Saleh, Nour El Arnaout, Nadine Sabra, Asmaa El Dakdouki, Zahraa Chamseddine, Randa Hamadeh, Abed Shanaa, Mohamad Alameddine
<p><strong>Background: </strong>In Lebanon, disadvantaged pregnant women show poor maternal outcomes due to limited access to antenatal care (ANC) and a strained health care system, compounded by ongoing conflicts and a significant refugee population. Despite substantial efforts to improve maternal health, the provision of maternal health services in primary health care centers (PHCs) still faces significant challenges. Mobile health (mHealth) interventions, particularly those using artificial intelligence (AI) and gamification, are proving effective in addressing gaps in maternal health services by offering scalable and accessible care.</p><p><strong>Objective: </strong>This study aimed to evaluate the effects of an AI-based gamified intervention, Gamification and Artificial Intelligence and mHealth Network for Maternal Health Improvement (GAIN MHI), on maternal health outcomes and uptake of ANC services among disadvantaged populations in Lebanon.</p><p><strong>Methods: </strong>The study was a community interventional trial with historical controls, conducted across 19 randomly allocated PHCs in 5 Lebanese governorates. Participants included pregnant women in their first trimester visiting PHCs. The intervention used mHealth tools, including educational mobile-based messages, appointment reminders, and the GAIN MHI app, which provided AI-driven and gamified learning for health care providers (HCPs). Data collected covered demographics, medical history, and maternal and neonatal health outcomes. Key outcome measures included uptake of health care services (eg, ANC visits, supplement intake, ultrasound completion, lab tests) and maternal and neonatal outcomes (eg, term delivery, normal delivery, abortion rate, neonatal morbidity, maternal complications).</p><p><strong>Results: </strong>This study included 3989 participants, divided between a control group (n=1993, 50%) and an intervention group (n=1996, 50%). Regression models adjusting for demographics, health, and obstetric characteristics showed significantly higher odds in the intervention group for completing 4 or more ANC visits (odds ratio [OR] 1.569, 95% CI 1.329-1.852, P<.05), completing lab tests (OR 1.821, 95% CI 1.514-2.191, P<.05), 2 or more ultrasound screenings (OR 7.984, 95% CI 6.687-9.523, P<.05), urine analysis (OR 4.399, 95% CI 3.631-5.330, P<.05), and supplement intake (OR 3.508, 95% CI 2.982-4.128, P<.05). Regarding outcomes, the intervention group had 29.5% increased odds of a term delivery (OR 1.295, 95% CI 1.095-1.532, P=.002) and 58% increased odds of avoiding neonatal morbidity (OR 1.580, 95% CI 1.185-2.108, P=.002). However, both groups showed decreased odds of normal delivery (intervention: OR 0.774, 95% CI 0.657-0.911; control: OR 0.823, 95% CI 0.701-0.964) and increased odds of maternal complications (intervention: OR 0.535, 95% CI 0.449-0.637; control: OR 0.586, 95% CI 0.474-0.723; P<.05).</p><p><strong>Conclusions: </strong>The GAIN MHI intervention effectively imp
背景:在黎巴嫩,由于获得产前保健(ANC)的机会有限和卫生保健系统紧张,加上持续的冲突和大量难民人口,处境不利的孕妇表现出不良的孕产妇结局。尽管为改善产妇保健作出了重大努力,但初级保健中心提供产妇保健服务仍然面临重大挑战。事实证明,移动保健(mHealth)干预措施,特别是使用人工智能(AI)和游戏化的干预措施,通过提供可扩展和可获得的护理,有效地解决了孕产妇保健服务方面的差距。目的:本研究旨在评估基于人工智能的游戏化干预、游戏化和人工智能以及孕产妇健康改善移动医疗网络(GAIN MHI)对黎巴嫩弱势群体孕产妇健康结果和ANC服务接受情况的影响。方法:该研究是一项具有历史对照的社区干预试验,在黎巴嫩5个省随机分配的19个初级保健中心进行。参与者包括孕期前三个月访问初级保健医院的孕妇。干预使用了移动健康工具,包括基于移动的教育信息、预约提醒和GAIN MHI应用程序,该应用程序为医疗保健提供者(hcp)提供人工智能驱动和游戏化学习。收集的数据包括人口统计、病史、孕产妇和新生儿健康结果。关键结果指标包括保健服务的接受情况(如产前检查、补充剂摄入、超声检查完成情况、实验室检查)以及产妇和新生儿结果(如足月分娩、正常分娩、流产率、新生儿发病率、产妇并发症)。结果:本研究共纳入3989名受试者,分为对照组(n=1993, 50%)和干预组(n=1996, 50%)。调整人口统计学、健康和产科特征的回归模型显示,干预组完成4次或4次以上ANC就诊的几率显著更高(优势比[or] 1.569, 95% CI 1.329-1.852, p)。结论:GAIN MHI干预有效改善了ANC的吸收,改善了孕产妇和新生儿的预后。我们的研究结果强调了移动医疗干预在提高医疗服务提供方面的潜力。为了维持这些改善,未来的研究应侧重于将移动医疗与其他解决社会经济和环境因素的干预措施相结合。这种方法将进一步优化弱势群体的孕产妇和新生儿健康结果。
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引用次数: 0
Evaluating the Clinical Effectiveness and Patient Experience of a Large Language Model-Based Digital Tool for Home-Based Blood Pressure Management: Mixed Methods Study. 评估基于大型语言模型的家庭血压管理数字工具的临床效果和患者体验:混合方法研究。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-11-03 DOI: 10.2196/68361
Alan Jelic, Igor Sesto, Luka Rotkvic, Luka Pavlovic, Nikola Erceg, Nina Sesto, Zeljko Kraljevic, Joshua Au Yeung, Amos Folarin, Richard Dobson, Petroula Laiou
<p><strong>Background: </strong>Hypertension, one of the most common cardiovascular conditions worldwide, necessitates comprehensive management due to its association with multiple health risks. Effective control often involves lifestyle changes and continuous monitoring, yet many individuals struggle to adhere to traditional management approaches. Digital health tools are emerging as promising alternatives, offering remote monitoring and real-time support. This study focuses on evaluating a digital tool specifically designed for hypertension management, analyzing its effectiveness, and gathering user perspectives on its functionality and impact.</p><p><strong>Objective: </strong>The primary objective of this study is to assess the effectiveness of a digital health tool in managing hypertension. Additionally, the study aims to understand user experiences and satisfaction levels to gauge the tool's acceptance and potential for long-term use. By analyzing data from a large cohort, we seek to determine whether the tool can contribute to meaningful reductions in blood pressure and support sustained engagement over time.</p><p><strong>Methods: </strong>The study includes a cohort of 5136 participants who used the digital hypertension management tool. This tool provides continuous blood pressure monitoring, real-time feedback, and personalized health recommendations, which are crucial for tailored intervention. Participants recorded their blood pressure values over time, and we tracked retention rates to measure adherence. An online survey was administered to gather user feedback, focusing on ease of use, satisfaction levels, and perceived health benefits.</p><p><strong>Results: </strong>Our analysis indicates a significant reduction in blood pressure values among users, with a positive correlation observed between the duration of use and the extent of blood pressure reduction. We performed a 1-sided Wilcoxon Rank Sum test to compare systolic blood pressure values in the first and last biweekly use intervals, and descriptive statistics were used to assess survey responses. High retention rates were observed, with 2583 (50.3%) participants using the tool after 1 year. Survey responses revealed high satisfaction, with users highlighting the tool's ease of use and noting reduced anxiety related to blood pressure management. These results suggest that users found the digital tool both effective and convenient.</p><p><strong>Conclusions: </strong>This study demonstrates the potential benefits of digital health tools in managing hypertension, emphasizing their ability to engage users over long periods and support blood pressure reduction. The high satisfaction rates and positive user feedback underscore the importance of user-centered design in creating effective health interventions. Overall, the findings suggest that digital tools, when designed with a focus on user experience, could be a valuable component in hypertension management strategies, complement
背景:高血压是世界范围内最常见的心血管疾病之一,由于其与多种健康风险相关,因此需要综合管理。有效的控制通常包括生活方式的改变和持续的监控,然而许多人很难坚持传统的管理方法。数字医疗工具正在成为有希望的替代方案,提供远程监测和实时支持。本研究的重点是评估一个专门为高血压管理设计的数字工具,分析其有效性,并收集用户对其功能和影响的看法。目的:本研究的主要目的是评估数字健康工具在管理高血压方面的有效性。此外,该研究旨在了解用户体验和满意度水平,以衡量工具的接受程度和长期使用的潜力。通过分析来自大型队列的数据,我们试图确定该工具是否有助于有意义的血压降低,并支持长期的持续参与。方法:该研究包括5136名使用数字高血压管理工具的参与者。该工具提供持续的血压监测、实时反馈和个性化的健康建议,这对量身定制的干预至关重要。参与者在一段时间内记录了他们的血压值,我们跟踪了坚持率来衡量坚持程度。进行了一项在线调查,以收集用户反馈,重点关注易用性、满意度水平和感知到的健康益处。结果:我们的分析表明,使用者的血压值显著降低,使用时间与血压降低程度呈正相关。我们采用单侧Wilcoxon秩和检验来比较第一个和最后一个双周使用间隔的收缩压值,并使用描述性统计来评估调查反应。观察到高保留率,1年后有2583(50.3%)参与者使用该工具。调查结果显示了很高的满意度,用户强调了该工具的易用性,并注意到减少了与血压管理相关的焦虑。这些结果表明,用户发现数字工具既有效又方便。结论:本研究证明了数字健康工具在管理高血压方面的潜在益处,强调了它们长期吸引用户和支持降血压的能力。高满意度和积极的用户反馈强调了以用户为中心的设计在制定有效的卫生干预措施方面的重要性。总的来说,研究结果表明,如果设计时注重用户体验,数字工具可以成为高血压管理策略的重要组成部分,补充传统的医疗保健方法。
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引用次数: 0
Within- and Between-Individual Compliance in Mobile Health: Joint Modeling Approach to Nonrandom Missingness in an Intensive Longitudinal Observational Study. 移动医疗中个体内部和个体之间的依从性:一项密集纵向观察研究中非随机缺失的联合建模方法。
IF 6.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-10-30 DOI: 10.2196/65350
Young Won Cho, Sy-Miin Chow, Jixin Li, Wei-Lin Wang, Shirlene Wang, Linying Ji, Vernon M Chinchilli, Stephen S Intille, Genevieve Fridlund Dunton
<p><strong>Background: </strong>Missing data are inevitable in mobile health (mHealth) and ubiquitous health (uHealth) research and are often driven by distinct within- and between-person factors that influence compliance. Understanding these distinct mechanisms underlying nonresponse can inform strategies to improve compliance and strengthen the validity of inferences about health behaviors. However, current missing data handling techniques rarely disentangle these different sources of nonresponse, especially when data are missing not at random.</p><p><strong>Objective: </strong>We demonstrate the usability of joint modeling in the mHealth context, showing how simultaneously accounting for the dynamics of health behavior and both within- and between-person missingness mechanisms can affect the validity of health behavior inferences. We also illustrate how joint modeling can inform distinct sources of (possibly nonignorable) missingness in studies using ecological momentary assessment and wearable devices. We provide a practical workflow for applying joint models to empirical data.</p><p><strong>Methods: </strong>We applied joint modeling on empirical data comprising 1 year of daily smartphone-based ecological momentary assessment data (affect and energetic feeling) and smartwatch-tracked physical activity (PA). The approach combined (1) a multilevel vector autoregressive model for examining the reciprocal influences between daily affect and PA, and (2) a multilevel probit model for missingness. Unlike conventional 2-stage imputation methods-which first impute missing data before fitting the main model-joint modeling handles missingness during model fitting without explicit imputation. Sensitivity analyses compared results from the proposed method to other missing data approaches that do not explicitly model missingness. A simulation study designed to mirror the temporally clustered (eg, consecutive days of missing data) and person-specific missingness patterns of the empirical data validated the feasibility of the proposed approach.</p><p><strong>Results: </strong>Sensitivity analysis indicated relative robustness of the autoregressive effects across missing data handling approaches, whereas cross-regressive effects could be detected only under the joint modeling but not with methods that did not simultaneously model missingness mechanisms. Specifically, under joint modeling approaches, participants had higher levels of PA on days following a previous day with higher self-report energy levels (95% credible interval [CrI] 0.012-0.049). Furthermore, the missing data model revealed both missing not at random and missing at random mechanisms. For example, lower PA predicted higher missingness in PA at the within-person level (95% CrI -1.528 to -1.441). Being employed was associated with higher missingness in device-tracked PA at the between-person level (95% CrI 0.148-0.574). Finally, simulation showed that joint modeling could improve the accuracy
背景:在移动健康(mHealth)和无处不在的健康(uHealth)研究中,数据缺失是不可避免的,并且通常是由影响依从性的不同内部和人与人之间的因素驱动的。了解这些不同的机制背后的不反应可以告知策略,以提高依从性和加强有关健康行为的推断的有效性。然而,目前的缺失数据处理技术很少能够理清这些不同的无响应来源,特别是当数据不是随机丢失时。目的:我们展示了联合建模在移动健康环境中的可用性,展示了如何同时考虑健康行为的动态以及人与人之间和人与人之间的缺失机制会影响健康行为推断的有效性。我们还说明了联合建模如何在使用生态瞬时评估和可穿戴设备的研究中告知不同的(可能不可忽视的)缺失来源。我们提供了将联合模型应用于经验数据的实际工作流程。方法:对基于智能手机的1年每日生态瞬间评估数据(情绪和精力感觉)和智能手表追踪的身体活动(PA)的经验数据进行联合建模。该方法结合了(1)用于检查日常影响和PA之间相互影响的多层向量自回归模型,以及(2)用于缺失的多层概率模型。与传统的两阶段插值方法(在拟合主模型之前首先输入缺失数据)不同,联合建模在模型拟合过程中处理缺失数据,而无需显式输入。敏感性分析将提出的方法的结果与其他没有明确建模缺失的缺失数据方法进行比较。一项模拟研究旨在反映时间聚类(例如,连续丢失数据的天数)和经验数据的个人特定丢失模式,验证了所提出方法的可行性。结果:敏感性分析表明,自回归效应在缺失数据处理方法中具有相对稳健性,而交叉回归效应只能在联合建模下检测到,而不同时对缺失机制建模的方法则无法检测到。具体来说,在联合建模方法下,参与者在前一天的第二天有更高的PA水平,自我报告的能量水平也更高(95%可信区间[CrI] 0.012-0.049)。此外,缺失数据模型揭示了非随机缺失和随机缺失机制。例如,较低的PA在个人水平上预示着较高的PA缺失(95% CrI为-1.528至-1.441)。在人与人之间的水平上,被雇用与更高的设备跟踪PA缺失相关(95% CrI 0.148-0.574)。最后,仿真结果表明,联合建模可以提高估计的精度,识别出不可忽略的缺失。结论:我们建议在收集大量纵向数据的移动健康/uHealth研究中使用多级分解联合建模来解决不可忽视的缺失。我们还建议使用缺失数据模型来探索缺失机制并为数据收集策略提供信息。
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JMIR mHealth and uHealth
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