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Infrarenal endovascular repair of abdominal aortic aneurysm with hostile aortic neck configuration by primary placement of an infrarenal Palmaz stent followed by an endoprosthesis with suprarenal fixation (the "Neoneck" technique). 通过首先放置肾下Palmaz支架,然后再植入肾上固定的假体(“Neoneck”技术),在肾下血管内修复具有不良主动脉颈构型的腹主动脉瘤。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202400452
André Pinheiro Ribeiro Alves, Queise da Costa Cettolin, Yasmin Falcon Lacerda, Mauricio de Amorim Aquino, Gustavo Dos Santos Domingues

Background: The Endovascular Repair (EVAR) is the first-choice technique for Abdominal Aortic Aneurysm (AAA). Treatment success is dependent on favorable anatomy and an adequate sealing zone formed by a straight aortic neck (slightly angled). Endoprostheses implanted at critical aortic angles (above 75º) may result in unfavorable results such as fracture, migration, and type Ia endoleak. The technique for creating a proximal "Neoneck" consists of implanting the Palmaz stent in the proximal neck of the AAA, before placement of the endoprosthesis, allowing remodeling and rectification of the aortic neck.

Objectives: To describe the "Neoneck" technique and report the early results of three cases with rectification of the proximal neck angle using a Palmaz stent, enabling treatment in these cases with angulated necks.

Methods: We analyzed data collected from patients in whom Palmaz stents were placed, constructing a proximal Neoneck, during EVAR for infrarenal AAA with very tortuous proximal aortic neck, assessing anatomy, devices and perioperative results, including success rates, complications, mortality, and patency in the short and medium term.

Results: All patients presented satisfactory evolution with immediate technical success. There were no cases of migration, fracture, or type Ia endoleaks. There was evidence of aneurysmal sac reduction after six months. There were no complications related to surgical access or deaths.

Conclusions: In cases of angled aortic necks, when open AAA repair is not possible, in the absence of ideal devices or in urgent cases, prior rectification of the aortic neck deploying the Palmaz stent is feasible and effective. Long-term studies are still needed to validate the technique and assess safety.

背景:血管内修复术(EVAR)是腹主动脉瘤(AAA)治疗的首选技术。治疗的成功取决于良好的解剖结构和由直主动脉颈形成的足够的密封区(略微倾斜)。在主动脉临界角(75º以上)处植入内假体可能导致骨折、移位和Ia型内漏等不良后果。制造近端“Neoneck”的技术包括在AAA近端颈部植入Palmaz支架,然后放置内假体,允许主动脉颈部重塑和矫正。目的:描述“Neoneck”技术,并报告三例使用Palmaz支架矫正颈近端角的早期结果,使这些颈成角的病例能够得到治疗。方法:我们分析了在EVAR中放置Palmaz支架,构建近端Neoneck的患者收集的数据,评估解剖结构,设备和围手术期结果,包括成功率,并发症,死亡率和中短期通畅。结果:所有患者均表现出满意的进展,并立即取得技术上的成功。无移位、骨折或Ia型内漏病例。6个月后动脉瘤囊缩小。没有与手术通路或死亡相关的并发症。结论:在主动脉颈有角度的情况下,当无法开放AAA修复时,在没有理想的设备或紧急情况下,预先矫正主动脉颈部署Palmaz支架是可行和有效的。仍然需要长期研究来验证该技术并评估其安全性。
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引用次数: 0
Instrument for assessing surgical skills related to performing a vascular anastomosis. 评估进行血管吻合手术技巧的仪器。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202400312
Gabriela de Oliveira Buril, Joseph Monteiro de Carvalho, Vânia Dos Santos Nunes-Nogueira

Technical skill is one of the most important components of surgical competence and must be thoroughly learned and developed over the course of surgical residency. However, there are still few instruments for directly appraising and quantifying surgical skill and the majority of centers rely on the subjective observations of tutors. The objective of this study was to conduct a scoping review on the subject of instruments for appraisal of surgical skills available for assessment of vascular anastomosis performed by vascular surgery residents. A review was conducted using the following search terms: "educational measurement", "vascular surgery", and "internship and residency". The initial search results comprised 616 articles. After application of the eligibility criteria, just four studies were included in the review, only one of which was conducted in Brazil. Three of the studies used Objective Structured Assessment of Technical Skill (OSATS) to assess residents. However, all used separate and different supplementary checklists for evaluation of specific skills related to anastomoses. Appropriate appraisal and precise feedback during residency training are an extremely important part of residents' training. Systematic and objective feedback enables errors to be corrected and skills to be polished. Since there is no instrument for assessment of the surgical skills needed to perform anastomosis, after completion of the review a rating instrument was proposed focused on this important skill that vascular surgery residents must acquire. The instrument comprises a compilation of the instruments reviewed and includes a proposed checklist for use in real-world settings.

技术技能是外科能力最重要的组成部分之一,必须在外科住院医师的过程中彻底学习和发展。然而,直接评价和量化手术技能的工具仍然很少,大多数中心依赖于导师的主观观察。本研究的目的是对血管外科住院医师进行血管吻合评估的外科技能评估工具进行范围审查。使用以下搜索词进行回顾:“教育测量”、“血管外科”和“实习和住院医师”。最初的搜索结果包括616篇文章。在适用资格标准后,只有四项研究被纳入审查,其中只有一项是在巴西进行的。其中三项研究使用客观结构化技术技能评估(OSATS)来评估居民。然而,他们都使用单独的和不同的补充检查表来评估与吻合有关的特定技能。住院医师培训中恰当的评估和准确的反馈是住院医师培训中极其重要的一部分。系统和客观的反馈使错误得到纠正,技能得到完善。由于没有评估吻合术所需手术技能的工具,在完成审查后,提出了一个评估工具,重点关注血管外科住院医师必须掌握的这一重要技能。该仪器包括已审查仪器的汇编,并包括在实际环境中使用的建议清单。
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引用次数: 0
The relationship between abdominal aortic aneurysm diameter and its risk factors: a retrospective cohort study. 腹主动脉瘤直径与其危险因素的关系:一项回顾性队列研究。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202301102
João Victor Domiciano Martins, Rodrigo Mendes, Ronald Luiz Gomes Flumignan, Luiz Carlos Uta Nakano, Jorge Eduardo de Amorim, Henrique Jorge Guedes

Background: Abdominal aortic aneurysm is defined as a focal and persistent dilatation of the abdominal portion of the aorta to a diameter ≥50% larger than the diameter of adjacent segments and involving all three layers of the vessel wall.

Objectives: To evaluate whether risk factors (diabetes mellitus, hypertension, dyslipidemia, smoking, and age) influence aneurysm expansion.

Methods: This is a retrospective observational study of a series of cases that included 299 patients treated from January 2007 to January 2020, separated into exposed and unexposed groups by risk factors. Student's t test was used to assess whether mean aneurysm diameters showed statistically relevant differences between groups. A multivariate regression analysis was also conducted with the same groups.

Results: Smokers had larger aneurysms than those who had never smoked (p=0.002) and than former smokers (p<0.01) and patients ≤65 years old had larger diameters compared to patients aged 66 to 75 years old (p=0.0226). There were no significant correlations with the other risk factors (diabetes mellitus, dyslipidemia, hypertension). Multivariate regression analysis confirmed the same result, but with a coefficient of determination of 0.0608. Furthermore, smokers, patients with hypertension, patients with dyslipidemia, and patients without diabetes had higher frequencies of much larger aneurysm diameters.

Conclusions: It was observed that age ≤65 years and current smoking were related to greater aneurysm diameter. In contrast, the same statistical relationship was not observed for hypertension, absence of diabetes, or dyslipidemia, since there was a greater frequency of discrepant values for these groups. Studies are needed with a more comprehensive analysis of determinants of aneurysm diameter.

背景:腹主动脉瘤被定义为主动脉腹部部分的局灶性持续扩张,其直径大于相邻节段的直径≥50%,并累及所有三层血管壁。目的:评价危险因素(糖尿病、高血压、血脂异常、吸烟和年龄)是否影响动脉瘤扩张。方法:对2007年1月至2020年1月期间接受治疗的299例患者进行回顾性观察性研究,按危险因素分为暴露组和未暴露组。采用学生t检验评估组间平均动脉瘤直径是否有统计学差异。对同一组进行多元回归分析。结果:吸烟者动脉瘤直径大于非吸烟者(p=0.002),大于戒烟者(p=0.002)。结论:年龄≤65岁、吸烟与动脉瘤直径增大有关。相比之下,在高血压、无糖尿病或血脂异常组中没有观察到相同的统计关系,因为这些组中差异值的频率更高。研究需要对动脉瘤直径的决定因素进行更全面的分析。
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引用次数: 0
Post-saphenous vein ablation compression therapy practices: a study among members of the Brazilian society of angiology and vascular surgery. 后隐静脉消融压迫治疗实践:巴西血管学和血管外科学会成员的研究。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202301822
Fabricio Duarte, Flavia Del Castanhel, Marcondes Antônio de Medeiros Figueiredo, Getúlio Rodrigues de Oliveira

Background: Despite considerable study, there is still no consensus defining the ideal compression regimen after ablation of the great saphenous vein with radio frequency or endolaser.

Objective: To identify the Brazilian Society of Angiology and Vascular Surgery members' current compression therapy practices after ablation of the great saphenous vein.

Methods: A multiple-choice electronic questionnaire on post-endovenous ablation compression was developed and made available on-line to Brazilian vascular surgeons for 60 days.

Results: A total of 430 responses were received, 362 (84.2%) of which were considered valid. Laser ablation was the predominant technique (73.5%) and the majority of procedures were conducted in hospitals or day hospitals. Ninety-four percent of the surgeons treated associated varicose veins in the same procedure, for which phlebectomy was the technique most employed. After ablation of the great saphenous vein, 99% of the surgeons applied compression immediately; 34.3% used 35 mmHg compression stockings, 26% preferred crepe bandages, and 12.4% opted for 20-30 mmHg compression stockings, with an average duration of 2.79 (±2 days). After this period, 88.4% used additional compression, with 20-30 mmHg compression stockings (80.9%) and an average duration of 39.3 (±24.0 days).

Conclusions: Compression therapy is widely employed after thermal ablation of the great saphenous vein. Practice immediately after ablation was divergent, but after the initial phase, the majority of surgeons prescribed additional compression, predominantly using 20-30 mmHg stockings.

背景:尽管进行了大量的研究,但射频或激光消融大隐静脉后理想的压迫方案仍未达成共识。目的:了解巴西血管学和血管外科学会成员目前对大隐静脉消融后的压迫治疗做法。方法:开发了一份关于静脉内消融后压迫的多项选择电子问卷,并在线提供给巴西血管外科医生60天。结果:共收到问卷430份,有效问卷362份(84.2%)。激光消融是主要技术(73.5%),大多数手术在医院或日间医院进行。94%的外科医生在同样的手术中治疗了相关的静脉曲张,其中静脉切除术是最常用的技术。大隐静脉消融后,99%的外科医生立即施加压迫;34.3%的患者使用35 mmHg的压缩袜,26%的患者选择绉布绷带,12.4%的患者选择20-30 mmHg的压缩袜,平均使用时间为2.79(±2天)。在此之后,88.4%的患者使用了额外的压缩,20-30 mmHg的压缩袜(80.9%),平均持续时间为39.3(±24.0天)。结论:大隐静脉热消融后广泛采用压迫治疗。消融后立即实施的做法是有分歧的,但在初始阶段之后,大多数外科医生都规定了额外的压迫,主要是使用20-30 mmHg的长袜。
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引用次数: 0
Efficacy and safety of paclitaxel drug-coated balloon angioplasty for stenosis of hemodialysis vascular access: 6-month results from a brazilian multicenter prospective study. 紫杉醇药物包被球囊血管成形术治疗血液透析血管通路狭窄的有效性和安全性:巴西一项为期6个月的多中心前瞻性研究结果
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202401032
Leonardo de Oliveira Harduin, Thiago Almeida Barroso, Julia Bandeira Guerra, Márcio Gomes Filippo, Leonardo Cortizo de Almeida, Carlos Alexandre Rosa Gama, Brunno Ribeiro Vieira, Renata Silveira Mello, Adriano Martins Galhardo, Jorge Paulo Strogoff-de-Matos

Background: Stenosis resulting from neointimal hyperplasia remains a significant concern associated with dysfunction of arteriovenous fistulas (AVF).

Objectives: To investigate the safety and efficacy of paclitaxel drug-coated balloon (DCB) angioplasty for treating failing AVFs.

Methods: Investigators analyzed 58 hemodialysis patients treated with RangerTM DCBs from December 2022 to December 2023 across four centers. Lesions treated were de novo or restenotic and located in the juxta-anastomosis, cannulation zone, and outflow segment. Patients were evaluated through physical examinations and Duplex ultrasound at 1, 3, and 6 months. The primary efficacy endpoint was target lesion primary patency at 1, 3, and 6 months, and the primary safety endpoint was freedom from serious adverse events through 30 days post-procedure. Secondary endpoints were access circuit primary patency and technical and procedural success.

Results: Nine patients (16%) had thrombosed access at the initial presentation, and 31 (53%) presented with recurrent stenosis. The target lesion primary patency rate at 6 months was 85.7%, and the access circuit primary patency rate at 6 months was 67.5%. No serious adverse events, either local or systemic, were reported. Sex, age, stenosis location, type of lesion, presence of thrombosis, lesion recurrence, diabetes status, or whether post-ballooning dilation was performed did not significantly affect the 6-month target lesion primary patency.

Conclusions: DCB angioplasty was shown to be safe and effective for treating peripheral stenosis in vascular access.

背景:由新生内膜增生引起的狭窄仍然是与动静脉瘘(AVF)功能障碍相关的一个重要问题。目的:探讨紫杉醇药物包被球囊(DCB)血管成形术治疗房颤衰竭的安全性和有效性。方法:研究人员分析了2022年12月至2023年12月在四个中心接受RangerTM DCBs治疗的58例血液透析患者。治疗的病变为新发或再狭窄,位于吻合口旁、插管区和流出段。分别于1、3、6个月时通过体格检查和双工超声对患者进行评估。主要疗效终点是1、3和6个月时的靶病变原发通畅,主要安全性终点是术后30天内无严重不良事件发生。次要终点是通路初级通畅和技术和程序成功。结果:9名患者(16%)在首次就诊时有血栓形成,31名患者(53%)出现复发性狭窄。靶病变6个月初发通畅率为85.7%,通路6个月初发通畅率为67.5%。没有严重的不良事件,无论是局部或全身,报告。性别、年龄、狭窄位置、病变类型、血栓形成、病变复发、糖尿病状况、是否进行球囊扩张对6个月目标病变原发通畅无显著影响。结论:DCB血管成形术治疗血管通路外周狭窄安全有效。
{"title":"Efficacy and safety of paclitaxel drug-coated balloon angioplasty for stenosis of hemodialysis vascular access: 6-month results from a brazilian multicenter prospective study.","authors":"Leonardo de Oliveira Harduin, Thiago Almeida Barroso, Julia Bandeira Guerra, Márcio Gomes Filippo, Leonardo Cortizo de Almeida, Carlos Alexandre Rosa Gama, Brunno Ribeiro Vieira, Renata Silveira Mello, Adriano Martins Galhardo, Jorge Paulo Strogoff-de-Matos","doi":"10.1590/1677-5449.202401032","DOIUrl":"10.1590/1677-5449.202401032","url":null,"abstract":"<p><strong>Background: </strong>Stenosis resulting from neointimal hyperplasia remains a significant concern associated with dysfunction of arteriovenous fistulas (AVF).</p><p><strong>Objectives: </strong>To investigate the safety and efficacy of paclitaxel drug-coated balloon (DCB) angioplasty for treating failing AVFs.</p><p><strong>Methods: </strong>Investigators analyzed 58 hemodialysis patients treated with Ranger<sup>TM</sup> DCBs from December 2022 to December 2023 across four centers. Lesions treated were de novo or restenotic and located in the juxta-anastomosis, cannulation zone, and outflow segment. Patients were evaluated through physical examinations and Duplex ultrasound at 1, 3, and 6 months. The primary efficacy endpoint was target lesion primary patency at 1, 3, and 6 months, and the primary safety endpoint was freedom from serious adverse events through 30 days post-procedure. Secondary endpoints were access circuit primary patency and technical and procedural success.</p><p><strong>Results: </strong>Nine patients (16%) had thrombosed access at the initial presentation, and 31 (53%) presented with recurrent stenosis. The target lesion primary patency rate at 6 months was 85.7%, and the access circuit primary patency rate at 6 months was 67.5%. No serious adverse events, either local or systemic, were reported. Sex, age, stenosis location, type of lesion, presence of thrombosis, lesion recurrence, diabetes status, or whether post-ballooning dilation was performed did not significantly affect the 6-month target lesion primary patency.</p><p><strong>Conclusions: </strong>DCB angioplasty was shown to be safe and effective for treating peripheral stenosis in vascular access.</p>","PeriodicalId":14814,"journal":{"name":"Jornal Vascular Brasileiro","volume":"24 ","pages":"e20240103"},"PeriodicalIF":0.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11841609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous aneurysm of a common digital artery: a rare entity. 指总动脉自发性动脉瘤:罕见病例。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202400832
Thilina Gunawardena

Aneurysms of arteries of the hand are rarely encountered. Literature reports such aneurysms in the distal ulnar artery, the palmar artery, and the digital arteries. Most are false aneurysms involving trauma-induced defects of the vessel wall. True aneurysms with intact intimal, medial, and adventitial layers of the arterial wall are more unusual. In this case report, we present a 77-year-old previously healthy lady who was diagnosed with a true aneurysm of a common digital artery when she presented with a pulsatile lump over her left palm.

手部动脉动脉瘤是罕见的。文献报道这类动脉瘤位于尺动脉远端、掌动脉和指动脉。大多数是假性动脉瘤,涉及外伤引起的血管壁缺陷。具有完整动脉壁内膜、内侧和外膜的真动脉瘤更为罕见。在本病例报告中,我们报告了一位77岁的健康女性,当她在左手掌出现搏动性肿块时,被诊断为真指总动脉动脉瘤。
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引用次数: 0
Accuracy of duplex ultrasound in peripheral artery disease: a systematic review and meta-analysis. 超声诊断外周动脉疾病的准确性:一项系统综述和荟萃分析。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202400332
Silfayner Victor Mathias Dias, Ronald Luiz Gomes Flumignan, Nelson Carvas, Wagner Iared

Lower limb peripheral artery disease (PAD) is highly prevalent. Current guidelines recommend duplex ultrasound (DUS) with spectral analysis for diagnosis. This systematic review and meta-analysis assessed the diagnostic accuracy of DUS in symptomatic PAD patients. We searched electronic databases for studies comparing DUS and arteriography. Arteries were analyzed individually and grouped into segments (aorto-common femoral, femoropopliteal, below the knee, and the entire lower limb). The meta-analysis estimated sensitivity, specificity, likelihood, and diagnostic odds ratios (DOR). Fifteen studies were included, analyzing 9,067 arteries. DUS accuracy for symptomatic PAD was 0.86 (95% CI 0.81-0.90) for sensitivity and 0.95 (95% CI 0.78-0.97) for specificity. The best results were observed for the femoropopliteal segment: sensitivity 0.86 (95% CI 0.80-0.90), specificity 0.95 (95% CI 0.93-0.97). The poorest performance was observed for the below-the-knee segment: sensitivity 0.78 (95% CI 0.60-0.89), specificity 0.92 (95% CI 0.78-0.97). Most studies had high and unclear risk of bias. There is significant heterogeneity in results, with a limited number of primary studies for each arterial segment, especially for the below-the-knee segment.

下肢外周动脉疾病(PAD)非常普遍。目前的指南推荐双超声(DUS)与光谱分析诊断。本系统综述和荟萃分析评估了DUS在有症状的PAD患者中的诊断准确性。我们检索了电子数据库中比较DUS和动脉造影的研究。单独分析动脉,并将其分组(主动脉-股总动脉、股腘动脉、膝下动脉和整个下肢动脉)。该荟萃分析估计了敏感性、特异性、可能性和诊断优势比(DOR)。纳入了15项研究,分析了9067条动脉。症状性PAD的DUS敏感性为0.86 (95% CI 0.81-0.90),特异性为0.95 (95% CI 0.78-0.97)。在股腘段观察到最好的结果:敏感性0.86 (95% CI 0.80-0.90),特异性0.95 (95% CI 0.93-0.97)。膝关节以下部位表现最差:敏感性0.78 (95% CI 0.60-0.89),特异性0.92 (95% CI 0.78-0.97)。大多数研究的偏倚风险高且不明确。结果存在显著的异质性,对每个动脉段的初步研究数量有限,尤其是对膝盖以下的动脉段。
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引用次数: 0
Portal-splenic-mesenteric venous thrombosis in COVID-19 patients: a systematic review. COVID-19患者门静脉-脾-肠系膜静脉血栓形成:系统综述。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202301282
Ricardo Zanetti Gomes, Matheus Von Jelita Salina, Vitor Hugo Moro Pironatto, Julia Kapp Lepinski, Tiago Daniel Gueiber, Beatriz Moreira Salles Juliatto, Milena Zadra Prestes, Camila Marinelli Martins

The COVID-19 pandemic affected millions of people worldwide. In addition to respiratory impairment, this viral infection can also provoke gastrointestinal symptoms caused by vascular disorders, such as portal-splenic-mesenteric venous thrombosis (PSMVT). This systematic review aimed to investigate the profile of patients who developed PSMVT concomitant with or after viral infection and its predominant outcomes. The database searches returned 214 articles. Of these, 40 case reports were included in the review, presenting a total of 41 cases of PSMVT addressed. Males were more prevalent (n=27; 65.85%), mean age was 51.54 years, and 19.57% had a previous history of endocrine diseases. Statistically significant relationships (p<0.05) were found between patient death and tachypnea at hospital admission (p=0.043) and between patient death and age (p=0.019). It was therefore possible to identify the main profiles and risk factors for PSMVT development and mortality of COVID-19 infected patients.

2019冠状病毒病大流行影响了全球数百万人。除了呼吸障碍外,这种病毒感染还可引起由血管疾病引起的胃肠道症状,如门静脉-脾静脉-肠系膜静脉血栓形成(PSMVT)。本系统综述旨在调查伴随病毒感染或病毒感染后发生PSMVT的患者及其主要结局。数据库搜索返回214篇文章。其中,40例病例报告被纳入审查,总共涉及41例PSMVT。男性更普遍(n=27;65.85%),平均年龄51.54岁,19.57%有内分泌疾病史。统计上显著的关系(p
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引用次数: 0
Brazilian Consensus Statement on Lipedema using the Delphi methodology. 使用德尔菲方法的巴西脂水肿共识声明。
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.1590/1677-5449.202301832
Alexandre Campos Moraes Amato, Ana Paula Rolim Maia Peclat, Rodrigo Kikuchi, Antonio Carlos de Souza, Mariana Thalyta Bertolin Silva, Roney Hans Prager de Oliveira, Daniel Augusto Benitti, Julio Cesar Peclat de Oliveira

Lipedema, historically underrecognized, has recently gained attention due to advancements in research and growing public awareness. The Brazilian Consensus Statement on Lipedema, developed by the Brazilian Society of Angiology and Vascular Surgery, aims to establish clear recommendations for the diagnosis, treatment, and management of lipedema. Using the Delphi methodology, experts elaborated 90 statements about lipedema, which were then evaluated by a panel of 113 professionals. The statements were analyzed using SurveyMonkey, with a 75% agreement threshold required for their inclusion in the consensus statement. Most statements achieved significant consensus, with only 9 topics requiring further investigation. This consensus statement highlights the complexity of lipedema, the effectiveness of conservative treatment over surgery, the need for multidisciplinary approaches, and the importance of awareness to reduce underdiagnosis and stigma. It also underscores the ongoing need for research to develop more effective management strategies.

由于研究的进步和公众意识的提高,历来未被充分认识的脂肪水肿最近得到了关注。由巴西血管学和血管外科学会制定的巴西脂水肿共识声明旨在为脂水肿的诊断、治疗和管理建立明确的建议。使用德尔菲方法,专家们详细阐述了90个关于脂肪水肿的陈述,然后由113名专业人员组成的小组进行评估。这些陈述是使用SurveyMonkey进行分析的,75%的同意阈值要求将其纳入共识陈述。大多数声明达成了重要的共识,只有9个主题需要进一步调查。这一共识声明强调了脂肪水肿的复杂性、保守治疗优于手术治疗的有效性、多学科方法的必要性以及减少诊断不足和污名的重要性。它还强调目前需要进行研究,以制定更有效的管理战略。
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引用次数: 0
Andexanet alfa for oral fxa inhibitor-associated major acute intracerebral hemorrhage: insights into clinically relevant thromboembolic events from the ANNEXA-I study. anddexanet alfa用于口服fxa抑制剂相关的严重急性脑出血:来自ANNEXA-I研究的临床相关血栓栓塞事件的见解
IF 0.8 Q4 PERIPHERAL VASCULAR DISEASE Pub Date : 2025-01-20 eCollection Date: 2024-01-01 DOI: 10.1590/1677-5449.202401332
Mateo Porres-Aguilar, Luis Antonio Meillon-Garcia, João Carlos de Campos Guerra
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引用次数: 0
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Jornal Vascular Brasileiro
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