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Implementation of the 2015 Guidelines on the standardization of protocols in Radiological Diagnostics in the ASL BT 2015年ASL BT放射诊断方案标准化指南的实施
Pub Date : 2023-03-31 DOI: 10.36017/jahc202351131
Claudia Ferraro, Samantha Cornacchia, Giuseppe Walter Antonucci, Maria Urbano, Giuseppe Guglielmi
Drafting of standardized protocols referring to standard patients according to the 2015 National Guidelines, each of which will be associated with a dose index (“dose class”), pursuant to Legislative Decree 101/2020, article 161, paragraph No. 6.study, data were collected from the execution on at least 5 patients of the practices admitted to standardization, for each hospital belonging to the ASL BT, using a CR detector and the values of the set parameters were recorded (kV, mA, exposure time, fi e-bed distance, focus-detector distance, field size, SEV, use or not of the AEC, possible use of the anti-diffusion grid). For each protocol, the associated effective dose was then calculated and the corresponding dose class assigned.Starting from the analysis of the data, 33 standard protocols were proposed for the execution of bone densitometric radiographic examinations, with a single densitometric model, and traditional radiology with two different OPT equipment and a remote-controlled model, installed in the ASL BT facilities.The study represents the proposal of 33 standard protocols for the execution of radiological examinations on the examined equipment, for each of which the associated dose class has been verified, which agrees with the reference one. Starting from the protocols obtained, it has been shown that the use of AEC involves a dose saving for the patient. In the ASL BT it is therefore possible to proceed with the implementation of the Guidelines.
根据2015年国家指南起草涉及标准患者的标准化方案,根据第101/2020号法令第161条第6段,每个标准患者将与剂量指数(“剂量等级”)相关联。研究中,收集了至少5例标准化实践患者的执行数据,每个医院属于ASL BT,使用CR检测器并记录设置参数的值(kV, mA,暴露时间,床位距离,焦点检测器距离,场大小,SEV,使用或不使用AEC,可能使用抗扩散网格)。对于每个方案,然后计算相关的有效剂量并指定相应的剂量等级。从数据分析出发,提出了33个标准方案,用于执行骨密度放射检查,使用单一密度测量模型,传统放射学使用两种不同的OPT设备和一个远程控制模型,安装在ASL BT设施中。这项研究提出了对被检查设备进行放射检查的33项标准规程,每项规程的相关剂量等级都已核实,与参考标准一致。从获得的方案开始,已经表明使用AEC可以为患者节省剂量。因此,在ASL BT中,可以继续实施指南。
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引用次数: 0
Comparison of two pre-treatment verification methods for arc – IMRT plans 弧- IMRT计划两种预处理验证方法的比较
Pub Date : 2023-03-31 DOI: 10.36017/jahc202351127
Marianna Aromando, Samantha Cornacchia, Marialuisa Doronzo, Maria Urbano, Giuseppe Guglielmi
In radiotherapy, the application of the IMRT arc technique, a special technique of external beam irradiation, while providing greater ballistic accuracy and personalization of treatment, as well as better speed of execution, requires special attention to the development of the treatment plan and its verification.Therefore, tools and methods of physical-health analysis that allow verification of the accuracy of the delivery of the radiant beam in the stages prior to treatment are essential. At the unit of Medical Physics at Dimiccoli Hospital Barletta, a prospective experimental study was conducted based on the comparison of two different methods of pre-treatment verification in patients treated for prostate cancer with the aim of increasing the performance of the treatment workflow.A comparative evaluation of gamma analysis results on images acquired with a 2D flat panel detector EPID (Electronic Portal Imaging Device) on the one hand and a 2D ionizing chambers detector on the other hand was conducted. The study sample included 38 patients undergoing radiotherapy with IMRT between December 2021 and October 2022, and each subject was studied and verified with both methods.The results of gamma analysis conducted with the two methods of pre-treatment verification of patients with prostate cancer are superimposable. In addition, with EPID we have a significant saving of machine time and thus allows an increase in the number of patients undergoing daily radiotherapy.In light of internationally accepted dosimetric and radiation protection accuracy standards according to Decree 101/2020, pre-treatment verification of dose distributions, using a 2D flat panel detection system (EPID), was found to be in line with waiting list reduction goals.
在放射治疗中,IMRT弧线技术是一种特殊的外射技术,在提供更高的弹道精度和个性化治疗以及更好的执行速度的同时,需要特别注意治疗计划的制定及其验证。因此,身体健康分析的工具和方法必须能够在治疗前阶段验证辐射光束传输的准确性。在Barletta Dimiccoli医院的医学物理单元,为了提高治疗流程的性能,在比较前列腺癌患者治疗前验证的两种不同方法的基础上,进行了一项前瞻性实验研究。对二维平板探测器EPID (Electronic Portal Imaging Device)和二维电离室探测器采集的图像进行了伽玛分析结果的对比评价。研究样本包括在2021年12月至2022年10月期间接受IMRT放疗的38例患者,每个受试者都使用两种方法进行研究和验证。用两种方法对前列腺癌患者进行治疗前验证的伽马分析结果是重叠的。此外,有了EPID,我们大大节省了机器时间,从而增加了每天接受放疗的患者数量。根据国际公认的剂量学和辐射防护精度标准,根据第101/2020号法令,使用二维平板检测系统(EPID)对剂量分布进行预处理验证,发现符合减少等候名单的目标。
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引用次数: 0
Development of an organisational model for the preparation of the mRNA-bnt162B2 vaccine: the experience of the Clinical Galenics Laboratory of the Hospital Pharmacy of the Mauriziano Hospital, Turin 研制mRNA-bnt162B2疫苗的组织模式:都灵Mauriziano医院药房临床盖伦学实验室的经验
Pub Date : 2023-02-15 DOI: 10.36017/jahc2302-02
Eleonora Chiaramonte, Kristela Bushkolaj, Paola Aluffi, Rosanna Borello, G. Galota, Annalisa Luchin, Emma Miotto, Antonietta Smaldone, Domenico Tripodi, Mario Michelotti, M. Bellero, Alessandra Bianco, G. Fazzina, M. Marcato, S. Masucci, Danilo Pennetta, M. Azzolina, A. Gasco
The centralised preparation of the mRNA-bnt162B2 vaccine at the Clinical Galenics Laboratory of the Hospital Pharmacy of the Mauriziano Hospital in Turin is an organisational model designed to guarantee the quality of the drug to be administered, the safety of both the vaccinee and the vaccinating personnel, and the traceability of all operations performed. The preparation in ready-for-use syringes individually packaged and labelled, according to the Good Manufacturing Practice (GMP) of the Official Pharmacopoeia, was entrusted to the Biomedical Laboratory Technician (BLT) under the responsibility of the Hospital Pharmacist. In compliance with the GMP, the model was developed through dedicated premises, specific staff training and written procedures concerning the handling of vaccines. The entire production process was guaranteed by: a Hospital Pharmacist and two interchangeable BLTs, one preparer and one assistant. They were necessary to maintain the aseptic technique and the cross-checking of all operations. Labels were prepared showing qualitative-quantitative composition, batch and expiry date, validity of the preparation, pharmacist's signature. The label applied to each syringe, together with the daily work plan, ensured traceability of the process at every stage. The efficient model proposed has always proved adaptable to the changes that characterised the vaccination campaign. From 27/12/2020 to 31/03/2022 a total of 48.017 doses were prepared. The centralisation of the vaccine preparation in the Clinical Galenics Laboratory of the Hospital Pharmacy also reduced handling errors, as well as the waste from unused residues, which proved to be only 0.08%.
在都灵Mauriziano医院药房临床Galenics实验室集中制备mRNA-bnt162B2疫苗是一种组织模式,旨在保证所给药物的质量、接种者和接种人员的安全以及所进行的所有操作的可追溯性。根据《官方药典》的良好生产规范(GMP),将即用型注射器的制备单独包装和贴标签,委托给医院药剂师负责的生物医学实验室技术员(BLT)。根据GMP,该模型是通过专门的场所、专门的工作人员培训和有关疫苗处理的书面程序开发的。整个生产过程由以下人员保证:一名医院药剂师和两名可互换的blt,一名制备人员和一名助理。它们对于保持无菌技术和所有操作的交叉检查是必要的。制作标签,显示定性定量组成,批号和有效期,制剂的有效性,药剂师的签名。每个注射器上的标签以及日常工作计划,确保了每个阶段过程的可追溯性。所提出的有效模型一直被证明能够适应疫苗接种运动所特有的变化。从2020年12月27日至2022年3月31日,共制备了48.017剂。将疫苗制备集中在医院药房临床盖伦学实验室也减少了处理错误,以及未使用残留物的浪费,这一比例仅为0.08%。
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引用次数: 0
Development of an organisational model for the preparation of the mRNA-bnt162B2 vaccine: the experience of the Clinical Galenics Laboratory of the Hospital Pharmacy of the Mauriziano Hospital, Turin 研制mRNA-bnt162B2疫苗的组织模式:都灵Mauriziano医院药房临床盖伦学实验室的经验
Pub Date : 2023-02-15 DOI: 10.36017/jahc202351137
Eleonora Chiaramonte, Kristela Bushkolaj, Paolo Aluffi, Rosanna Borello, Giusi Galota, Annalisa Luchin, Emma Miotto, Antonietta Smaldone, Domenico Tripodi, Mario Michelotti, Marco Bellero, Alessandra Bianco, Giovanna Fazzina, Maddalena Marcato, Simona Masucci, Danilo Pennetta, Maria Carmen Azzolina, Annalisa Gasco
The centralised preparation of the mRNA-bnt162B2 vaccine at the Clinical Galenics Laboratory of the Hospital Pharmacy of the Mauriziano Hospital in Turin is an organisational model designed to guarantee the quality of the drug to be administered, the safety of both the vaccinee and the vaccinating personnel, and the traceability of all operations performed. The preparation in ready-for-use syringes individually packaged and labelled, according to the Good Manufacturing Practice (GMP) of the Official Pharmacopoeia, was entrusted to the Biomedical Laboratory Technician (BLT) under the responsibility of the Hospital Pharmacist.In compliance with the GMP, the model was developed through dedicated premises, specific staff training and written procedures concerning the handling of vaccines. The entire production process was guaranteed by: a Hospital Pharmacist and two interchangeable BLTs, one preparer and one assistant. They were necessary to maintain the aseptic technique and the cross-checking of all operations. Labels were prepared showing qualitative-quantitative composition, batch and expiry date, validity of the preparation, pharmacist’s signature. The label applied to each syringe, together with the daily work plan, ensured traceability of the process at every stage.The efficient model proposed has always proved adaptable to the changes that characterised the vaccination campaign. From 27/12/2020 to 31/03/2022 a total of 48.017 doses were prepared. The centralisation of the vaccine preparation in the Clinical Galenics Laboratory of the Hospital Pharmacy also reduced handling errors, as well as the waste from unused residues, which proved to be only 0.08%.
在都灵Mauriziano医院药房临床Galenics实验室集中制备mRNA-bnt162B2疫苗是一种组织模式,旨在保证所给药物的质量、接种者和接种人员的安全以及所进行的所有操作的可追溯性。根据《官方药典》的良好生产规范(GMP),将即用型注射器的制备单独包装和贴标签,委托给医院药剂师负责的生物医学实验室技术员(BLT)。根据GMP,该模型是通过专门的场所、专门的工作人员培训和有关疫苗处理的书面程序开发的。整个生产过程由以下人员保证:一名医院药剂师和两名可互换的blt,一名制备人员和一名助理。它们对于保持无菌技术和所有操作的交叉检查是必要的。制作标签,显示定性定量组成,批号和有效期,制剂的有效性,药剂师的签名。每个注射器上的标签以及日常工作计划,确保了每个阶段过程的可追溯性。所提出的有效模型一直被证明能够适应疫苗接种运动所特有的变化。从2020年12月27日至2022年3月31日,共制备了48.017剂。将疫苗制备集中在医院药房临床盖伦学实验室也减少了处理错误,以及未使用残留物的浪费,这一比例仅为0.08%。
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引用次数: 0
Training: implementation of laboratory tests for molecular, antigenic and serological diagnostics of SARS CoV2 and reorganization of work activities 培训:实施SARS CoV2分子、抗原和血清学诊断的实验室检测,重组工作活动
Pub Date : 2023-02-14 DOI: 10.36017/jahc2302-01
Claudia Corinaldesi, Rosa Maria Oliverio, L. Mitello, Marina Macari, Marina Bertolini
The U.O.C. of Microbiology and Virology experienced a disruption of work activity in the year 2020 due to the COVID 19 emergency .. On 3 April 2020 the U.O.C. of Microbiology and Virology of the San Camillo-Forlanini Company is included in the network of CORONET laboratories for molecular, antigenic and serological diagnostics of SARS CoV2. To cope with this emergency it was necessary to reorganize the entire laboratory activity, so as to be able to carry out both the routine activities and those concerning the diagnosis of SARS CoV2, coming not only from the San Camillo-Forlanini company, but also from the territorial ASL, Case di Cira, RSA, Drive in and Walk in. The complex and unexpected scenario brought out the need to quickly create an organizational model that could guarantee the execution of routine exams, but also provide a diagnostic priority for SARS-Cov2. The initial phases were difficult on various fronts: in a very short time the laboratory technicians had to learn the most sophisticated molecular techniques indispensable for the diagnosis of SARS CoV2, moreover, it was necessary to face the serious shortage of reagents difficult to find on the market. Europe. However, the biggest challenge was managing the hundreds of daily samples. Thanks to the reorganization implemented, the U.O.C. of Microbiology and Virology is able to carry out surveys on increasingly large population samples, in compliance with regional and national guidelines.
由于COVID - 19紧急情况,2020年微生物学和病毒学u.o.c的工作活动中断。2020年4月3日,圣卡米洛-弗拉尼尼公司微生物学和病毒学u.o.c被纳入冠状病毒实验室网络,进行SARS冠状病毒2的分子、抗原和血清学诊断。为了应对这一紧急情况,有必要重组整个实验室的活动,以便能够开展常规活动和与SARS CoV2诊断有关的活动,这些活动不仅来自圣卡米拉-弗兰尼尼公司,还来自领土ASL, Case di Cira, RSA, Drive in和Walk in。这种复杂和意外的情况使我们有必要迅速建立一个组织模型,既能保证常规检查的执行,又能优先诊断SARS-Cov2。最初阶段在各个方面都很困难:在很短的时间内,实验室技术人员必须学习诊断SARS CoV2所必需的最复杂的分子技术,此外,必须面对市场上难以找到的试剂严重短缺的问题。欧洲。然而,最大的挑战是管理每天数百个样本。由于实施了重组,微生物学和病毒学联合委员会能够按照区域和国家指导方针,对越来越多的人口样本进行调查。
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引用次数: 0
Training: implementation of laboratory tests for molecular, antigenic and serological diagnostics of SARS CoV2 and reorganization of work activities 培训:实施SARS CoV2分子、抗原和血清学诊断的实验室检测,重组工作活动
Pub Date : 2023-02-14 DOI: 10.36017/jahc202351140
Claudia Corinaldesi, Rosa Maria Oliverio, Lucia Mitello, Marina Macari, Marina Bertolini
The U.O.C. of Microbiology and Virology experienced a disruption of work activity in the year 2020 due to the COVID 19 emergency .On 3 April 2020 the U.O.C. of Microbiology and Virology of the San Camillo-Forlanini Company is included in the network of CORONET laboratories for molecular, antigenic and serological diagnostics of SARS CoV2.To cope with this emergency it was necessary to reorganize the entire laboratory activity, so as to be able to carry out both the routine activities and those concerning the diagnosis of SARS CoV2, coming not only from the San Camillo-Forlanini company, but also from the territorial ASL, Case di Cira, RSA, Drive in and Walk in.The complex and unexpected scenario brought out the need to quickly create an organizational model that could guarantee the execution of routine exams, but also provide a diagnostic priority for SARS-Cov2.The initial phases were difficult on various fronts: in a very short time the laboratory technicians had to learn the most sophisticated molecular techniques indispensable for the diagnosis of SARS CoV2, moreover, it was necessary to face the serious shortage of reagents difficult to find on the market. Europe.However, the biggest challenge was managing the hundreds of daily samples.Thanks to the reorganization implemented, the U.O.C. of Microbiology and Virology is able to carry out surveys on increasingly large population samples, in compliance with regional and national guidelines.
2020年,由于COVID - 19紧急情况,微生物学和病毒学u.o.c的工作活动中断。2020年4月3日,圣卡米洛-弗拉尼尼公司微生物学和病毒学u.o.c被纳入冠状病毒实验室网络,用于SARS CoV2的分子、抗原和血清学诊断。为了应对这一紧急情况,有必要重组整个实验室的活动,以便能够开展常规活动和与SARS CoV2诊断有关的活动,这些活动不仅来自圣卡米拉-弗兰尼尼公司,还来自领土ASL, Case di Cira, RSA, Drive in和Walk in。这种复杂和意外的情况使我们有必要迅速建立一个组织模型,既能保证常规检查的执行,又能优先诊断SARS-Cov2。最初阶段在各个方面都很困难:在很短的时间内,实验室技术人员必须学习诊断SARS CoV2所必需的最复杂的分子技术,此外,必须面对市场上难以找到的试剂严重短缺的问题。欧洲。然而,最大的挑战是管理每天数百个样本。由于实施了重组,微生物学和病毒学联合委员会能够按照区域和国家指导方针,对越来越多的人口样本进行调查。
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引用次数: 0
The activity of the speech therapist at the time of COVID 19: survey of the Campania region 新冠肺炎时期语言治疗师的活动:坎帕尼亚地区的调查
Pub Date : 2022-11-14 DOI: 10.36017/jahc2211-02
Girolamo Verlanti, Tiziana Sivo, Maria Francesca Zupi, Federica Brancati, Sara Panizzolo
Our government has enacted restrictive and isolation measures, also in the field of rehabilitation, to combat and contain the spread of the SARS-CoV-2 virus. These have had a major impact on the working methods and activities performed by the Speech Therapist. The Board of Speech Therapists of the Interprovincial Order of NA-AV-BN-CE conducted an anonymous survey to observe the phenomenon. The study aimed to assess how and to what extent the health measures in place influenced occupational activities and work-related discomfort. A questionnaire was structured to investigate, anonymously, different areas of professional interest (how therapeutic activities are carried out, work-related stress management, changes in human relations, specific needs), disseminated via the web thanks to the Google platform, and available from 15/06/2020 to 15/11/2022 for all speech therapists belonging to the interprovincial order of NA-AV-BN-CE. 161 Speech Therapists, aged between 21 and 40 years (73.9 per cent), took part in the survey. They worked mainly in a combined telerehabilitation and outpatient setting (64.12 per cent), and were provided with appropriate PPE for the treatment (65.8 per cent). Speech and language therapists reported a low to medium level of frustration (63.9%) and work-related stress (63.4%) for telerehabilitation treatment, to a high level for outpatient or home treatment (69.6%). Medium to high values (81.4%) of anxiety, worry and work-related distress are reported, favoured by social isolation and a perception of less support among colleagues, with a perceived need for psychological support from specialised figures to manage the emotional burden. The results suggest a medium to high level of work-related discomfort during the pandemic period, mainly for speech therapists who performed outpatient/domiciliary activities, entailing the risk of developing psychological distress. Further research should be undertaken, with multicentre and larger sample size studies, to define the relationships between the working methods promoted, work-related stress and the need to manage it.
我国政府已制定了限制和隔离措施,包括在康复领域,以对抗和遏制SARS-CoV-2病毒的传播。这些都对言语治疗师的工作方法和活动产生了重大影响。全国语言治疗师协会跨省会语言治疗师委员会进行了一项匿名调查,以观察这一现象。这项研究旨在评估现有的健康措施如何以及在多大程度上影响职业活动和与工作有关的不适。问卷的结构是匿名调查不同领域的专业兴趣(如何开展治疗活动,工作压力管理,人际关系的变化,特殊需求),通过谷歌平台通过网络传播,并于2020年6月15日至2022年11月15日提供给属于NA-AV-BN-CE跨省顺序的所有语言治疗师。共有161名言语治疗师(73.9%)参与调查,年龄介乎21至40岁。他们主要在远程康复和门诊结合的环境中工作(64.12%),并为治疗提供适当的个人防护装备(65.8%)。言语和语言治疗师报告了远程康复治疗中低水平的挫败感(63.9%)和工作压力(63.4%),门诊或家庭治疗的高水平(69.6%)。据报告,焦虑、担忧和与工作有关的痛苦程度中至高(81.4%),主要是社会孤立和认为同事之间的支持较少,认为需要专业人士的心理支持来管理情绪负担。结果表明,在大流行期间,与工作有关的不适程度为中等至高度,主要是从事门诊/住家活动的语言治疗师,有产生心理困扰的风险。应进行进一步的研究,包括多中心和更大的样本量研究,以确定所提倡的工作方法、与工作有关的压力和管理压力的需要之间的关系。
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引用次数: 0
Clinical risk management in the 99m-Tc-MIBI quality control procedure in nuclear medicine. Case study. 核医学99m-Tc-MIBI质量控制程序的临床风险管理。案例研究。
Pub Date : 2022-11-12 DOI: 10.36017/jahc2211-01
Rossetti Filippo, Rizzo Vincenzo, De Francesco Leonardo, Spirito Marco, Farese Raffaele, Pastore Simone, Frasca Carmine
The work is based on daily work protocols used within a Nuclear Medicine Operating Unit in which all modern radiopharmaceuticals are used and quality control procedures are applied to the latter. It is essential to underline, also with the production of this article, the importance of quality controls and the collaboration of the various figures in the field in order to avoid inappropriate injection of radiopharmaceuticals and to guarantee the safety and appropriateness of the procedures with an effective clinical risk management in contrast and prevent technical errors and penalizing the injection and acquisition of diagnostic tests, sometimes urgent, and indispensable for the diagnosis of even delicate pathologies.
这项工作是根据核医学操作股使用的日常工作规程进行的,该股使用所有现代放射性药物,并对后者实施质量控制程序。在编写这篇文章的同时,还必须强调质量控制的重要性以及该领域各方的合作,以避免放射性药物的不当注射,并通过有效的临床风险管理来保证程序的安全性和适当性,防止技术错误和处罚注射和获取诊断测试(有时是紧急的),即使是细微病变的诊断也离不开它。
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引用次数: 0
4D Free-Breathing Sequence For The Study Of Pancreatic Lesions In MRI 3 Tesla 4D自由呼吸序列对MRI 3特斯拉胰腺病变的研究
Pub Date : 2022-10-08 DOI: 10.36017/jahc2210-01
Curatolo Calogero, Siino Manfredi, Cannella Roberto, Loverro Giuseppe, Brancatelli Giuseppe
Pancreatic cancer is the fourth leading cause of cancer death in both the United States and Europe. A fundamental role in the characterization, early diagnosis, and staging of pancreatic cancer is played by Magnetic Resonance. An innovative and recently implemented sequence, the 4D Free-Breathing sequence, is demonstrating remarkable efficiency in the characterization of pancreatic lesions, as it allows to obtain images with high temporal resolution on the arterial phase, maintaining high spatial and temporal resolution, with the patient free breathing and with compensation of respiratory movement artifacts. The aim of this study was to analyze the 4D Free-Breathing sequence technique and to evaluate its advantages in terms of image quality and diagnostic value in the characterization of pancreatic lesions. The 4D Free Breathing sequence replaces the acquisition of the classic arterial post-contrast phase obtained with the 3D-THRIVE sequence: after a first acquisition of the k-space data in the non-contrast phase (lasting 58 seconds), multiple arterial subphases, each one lasting about 5 seconds, will be acquired with a complete coverage of the post-contrast phase of about 90 seconds. This sequence exploits the k-space sampling technique called "Stack of Stars", based on a radial sampling in the XY plane. In detail, along the slice phase-encoding direction (kz), uniform Cartesian-grid sampling is maintained. Within each kz-encoded plane, radial data is collected with consecutive views (1 per sequence repetition time TR) rotated by a golden-angle of 111.25°, allowing the sampling of a complete circle, also determining a considerably reduced presence of breath artifacts.
胰腺癌是美国和欧洲癌症死亡的第四大原因。磁共振在胰腺癌的特征、早期诊断和分期中起着重要作用。最近实施的一项创新序列,4D自由呼吸序列,在胰腺病变表征方面显示出显著的效率,因为它允许在动脉期获得高时间分辨率的图像,保持高空间和时间分辨率,患者自由呼吸并补偿呼吸运动伪像。本研究的目的是分析4D自由呼吸序列技术,并评估其在图像质量和诊断胰腺病变特征方面的优势。4D自由呼吸序列取代了3D-THRIVE序列获得的经典动脉造影后期的采集:在非造影期(持续58秒)首次采集k空间数据后,将获得多个动脉亚期,每个亚期持续约5秒,并获得约90秒的造影后期的完整覆盖。这个序列利用了k空间采样技术,称为“星星堆栈”,基于XY平面的径向采样。详细地说,沿着切片相位编码方向(kz),保持均匀的笛卡尔网格采样。在每个kz编码平面内,径向数据是通过连续视图(每个序列重复时间TR 1)以111.25°的黄金角度旋转收集的,允许对一个完整的圆圈进行采样,也确定大大减少了呼吸伪影的存在。
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引用次数: 0
Refocus flip angle modulation on the pd tse sequences in the magnetic resonance imaging of the knee, for the evaluation of meniscal injuries 重新聚焦翻转角度调制pd tse序列在膝关节的磁共振成像,为评估半月板损伤
Pub Date : 2022-07-30 DOI: 10.36017/jahc2207-06
Curatolo Calogero, Lisanti Sara, Daricello Marco, Caruso Virginia, Candela Fabrizio, Cimino Pietro, Spoto Italia, Cutaia Giuseppe, Loverro Giuseppe, Galia Massimo
The Radiofrequency Refocused Echo Spin-Echo Echo-Train Rapid-Acquisition sequences, known as Turbo Spin Echo or Fast Spin Echo are the most commonly used sequences in Magnetic Resonance as they provide a notable contribution in morphological and anatomical terms, thanks to their high spatial and contrast resolution. Furthermore, they allow a higher signal noise ratio than the other families of sequences thanks to the numerous refocusing pulses and thanks to a TR so long as to allow sampling as many K-space phase encodings as possible and with a complete recovery of the Longitudinal Magnetization. Finally, the multiple 180 ° pulses of these sequences reduce the inhomogeneities of the Magnetic Field by minimizing the phenomena of magnetic susceptibility. However, their application, especially in scanners with a high intensity of static magnetic field B0(1.5T and/or 3T)is prevented by the deposition of RF due to the long echo trains, which sometimes involve exceeding the limits of the specific absorption rate for patient safety. Over time, a common solution to the SAR problem has been the use of refocusing angles smaller than 180°(160°-140°-120°),which lead to its reduction at the cost, however, of an obvious penalty in terms of signal-to-noise ratio. In this study we present a modulation method of the Refocus Flip-Angle applied to the DP-TSE sequences in the evaluation of meniscal lesions in the study protocol of the Magnetic Resonance of the Knee, which exploits the phenomenon of the Pseudo-Steady-State(PSS), leading to a noticeable SARreduction without loss of SNR and also providing excellent contrast resolution
射频重聚焦回波自旋回波序列快速采集序列,被称为涡轮自旋回波或快速自旋回波序列,是磁共振中最常用的序列,因为它们在形态学和解剖学方面提供了显著的贡献,这要归功于它们的高空间和对比度分辨率。此外,由于大量的重聚焦脉冲和TR,它们允许比其他系列序列更高的信噪比,只要允许采样尽可能多的k空间相位编码,并完全恢复纵向磁化。最后,这些序列的多个180°脉冲通过最小化磁化率现象来降低磁场的不均匀性。然而,它们的应用,特别是在具有高强度静态磁场B0(1.5T和/或3T)的扫描仪中,由于长回波序列导致RF沉积而受阻,有时涉及超过患者安全的特定吸收率限制。随着时间的推移,SAR问题的一个常见解决方案是使用小于180°(160°-140°-120°)的重聚焦角,这可以降低成本,但在信噪比方面有明显的损失。在本研究中,我们提出了一种用于膝关节磁共振研究方案中半月板病变评估的DP-TSE序列的再聚焦翻转角调制方法,该方法利用了伪稳态(PSS)现象,导致显著的sarr降低而不损失信噪比,并提供了出色的对比度分辨率
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Journal of Advanced Health Care
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