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Association of Insomnia with Comorbidities among Patients Visiting Tertiary Care Hospitals Lahore 在拉合尔三级医院就诊的患者中失眠与合并症的关系
Pub Date : 2022-03-25 DOI: 10.54692/lgujls.2022.0601199
S. Khalid, M. Ulfat, S. Bashir, Tabeen Irfan, Kinza Seher, Milhan Tanveer, Fiza Latif, Fariha Mehdi, Z. Rashid, M. Riaz
Insomnia is a condition that affects an individual by inability to get sufficient quality sleep or problem in maintaining sleep that is important for healthy functioning, performance and wellbeing. There is very scarce data regarding insomnia and its relation with different diseases. The present study was aimed to find out the association of insomnia with comorbidities among patients visiting Tertiary Care Hospitals, Lahore. A cross sectional study was conducted from May 2019 to September 2019 in Tertiary Care Hospitals district Lahore. Interviews were conducted by researchers to collect data through Pre-Tested Questionnaire. Informed consent was first taken from all participants. Data were analyzed by using Chi-square to find out the association of insomnia with comorbidities through SPSS version 25.0. Thousand (n=1000) patients suffering from different diseases randomly selected to participate, of which 43.6% were male and 56.4% were female. Results of present study revealed that association of insomnia with the diseases such as cardiovascular diseases (p=0.05), diabetes mellitus m(p=0.001), gastrointestinal problems (p=0.034), premenstrual syndrome (p=0.00), joint pains (p=0.01) and prostate cancer (p=0.01) was found to be significant. While an insignificant association of insomnia was noticed with hypertension (p=0.850), hearing impairments (p=1.22), COPD (p=0.288). It was concluded that insomnia was most commonly present in the patients of cardiovascular diseases, diabetes mellitus, premenstrual syndrome, gastro-intestinal problems, joint pains and prostate cancer.
失眠是一种影响个体的状况,无法获得足够的高质量睡眠,或者无法维持对健康功能、表现和幸福很重要的睡眠。关于失眠及其与不同疾病的关系的资料很少。本研究旨在了解在拉合尔三级医院就诊的患者失眠与合并症的关系。2019年5月至2019年9月在拉合尔三级保健医院区进行了一项横断面研究。研究人员进行访谈,通过预测问卷收集数据。首先获得所有参与者的知情同意。数据采用卡方分析,通过SPSS 25.0版本分析失眠与合并症的关系。随机抽取1000例(n=1000)不同疾病的患者参与,其中男性43.6%,女性56.4%。本研究结果显示,失眠与心血管疾病(p=0.05)、糖尿病(p=0.001)、胃肠疾病(p=0.034)、经前综合征(p=0.00)、关节痛(p=0.01)、前列腺癌(p=0.01)等疾病有显著相关性。而失眠与高血压(p=0.850)、听力障碍(p=1.22)、慢性阻塞性肺病(p=0.288)的相关性不显著。结果表明,失眠最常见于心血管疾病、糖尿病、经前综合征、胃肠道疾病、关节痛和前列腺癌患者。
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引用次数: 0
Incidence of Psychiatric Disorders in Children affected with Intellectual Disability 智力残疾儿童精神疾病的发病率
Pub Date : 2022-03-25 DOI: 10.54692/lgujls.2022.0601200
S. Naz, Wajeeha Salamat, M. Aslam, S. Sharif, Shama Sadaf
Intellectual disability is caused by environmental influences, genetic disorders and infections including perinatal, postnatal and neonatal infections. Physical disabilities are also associated with intellectual disability (ID) children.Identification of ID patients occurred by test of intellectual disfunctioning. A cross sectional and analytical study was performed from September 2019 to March 2020on intellectually disabled children on the Pakistan Air Force (PAF) children school Lahore, Fountain house in Sargodha and Shadab institute of special education, Punjab, Pakistan. The level of intellectual disability was based on the intelligence quotient (IQ). In present study, out of 200 children, 80 children were suffered from this disease, 56 were males and 24 were females. Cases related to intellectual disability were identified with in different age groups such as age group 0-5 (N = 13), 6-10 (N = 27), 11-15 (N = 27), 16-20 (N = 10), 21-25 (N = 3) and 26-30 (N = 3). A total of 33.75% were belong to 6-10 years of age group. Out of 80 children 27.50% (N = 22) were affected due to malnutrition in pregnancy, 16.25% (N = 13) children had folic acid deficiency, 15% (N = 12) children were due to exposure to the chemicals or radiations in pregnancy, 21.25% (N = 17) children had hypothyroidism and 16% (N = 20) children had other gene disorder associated with intellectual disability. Proper recognition of disorder can play an important role in dealing with psychiatrists patients.
智力残疾是由环境影响、遗传疾病和感染(包括围产期、产后和新生儿感染)造成的。身体残疾也与智力残疾儿童有关。通过智力障碍测验对ID患者进行鉴定。2019年9月至2020年3月,对巴基斯坦空军拉合尔儿童学校、萨戈达Fountain house和旁遮普Shadab特殊教育学院的智障儿童进行了横断面分析研究。智力残疾的程度以智商(IQ)为基础。在本研究中,200名儿童中有80名儿童患有此病,其中56名是男性,24名是女性。智力障碍病例分布在0-5岁(N = 13)、6-10岁(N = 27)、11-15岁(N = 27)、16-20岁(N = 10)、21-25岁(N = 3)、26-30岁(N = 3)等不同年龄组,其中6-10岁占33.75%。在80名儿童中,27.50% (N = 22)的儿童因怀孕期间营养不良而受到影响,16.25% (N = 13)的儿童患有叶酸缺乏症,15% (N = 12)的儿童因怀孕期间接触化学物质或辐射而受到影响,21.25% (N = 17)的儿童患有甲状腺功能减退症,16% (N = 20)的儿童患有与智力残疾相关的其他基因疾病。对精神障碍的正确认识在治疗精神病患者中起着重要的作用。
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引用次数: 0
Prevalence and Associated Risk Factors of Coccidiosis in Small Ruminants in Dera Ghazi Khan, Punjab, Pakistan 巴基斯坦旁遮普省Dera Ghazi Khan地区小反刍动物球虫病患病率及相关危险因素
Pub Date : 2021-12-23 DOI: 10.54692/lgujls.2021.0504190
M. Avais, G. Rashid, M. Awais, S. Zaman, M. Arif Khan, Syed Saleem Ahmad, Sadia Amjad
The goal of the present research was to figure out the prevalence and risk factors of coccidiosis in goats and sheep in Dera Ghazi Khan. For this 752 (goats=376; sheep=376) fecal specimens were obtained, and were analyzed by coprological examination. The prevalence of coccidiosis in sheep (52.92 %) was significantly higher (P<0.05) than the goats (44.41 %). In females, infection with Eimeria was significantly higher (P<0.05) as compared to male animals. Coccidiosis was significantly more common (P<0.05) in sheep and goats aged ≤6 months compared to sheep and goats older than 6 months but less than a year, and older than a year. There was a clear distinction (P<0.05) in prevalence of coccidiosis in animals that are stall fed and housed in comparison with the animals that graze in open grasslands. Prevalence of coccidiosis in animals with low BCS was considerably higher (P<0.05) as compared to the animals in good health. The prevalence of Eimeria infection and fecal score had a significant correlation (P<0.05). Prevalence of coccidiosis was higher in August while in October it was lowest. The highest prevalence (56.78%) was of E. ovinoidal is followed in order by 47.23 % E. ahsata, 35.67 % E. parva, 30.15 % E. intricate, 26.63 % E. faurei and 19.09 % E. pallid in sheep. In case of goats, highest prevalence (68.86%) was of E. ninakohlyakimovae, followed by 59.88% E. alijevi, 53.29% E. arloingi, 46.70 % E. caprinaand 22.15 % E. hirci were among the most common Eimeria spp. It was concluded that different Eimeria spp. Prevailing in study area with variable risk factors and the incidence of coccidiosis in research area was affected by various risk variables.
本研究的目的是了解德拉加齐汗地区山羊和绵羊球虫病的流行情况及其危险因素。752(山羊=376;采集绵羊粪便标本376例,进行粪学检查。绵羊球虫病患病率(52.92%)显著高于山羊(44.41%)(P<0.05)。雌性艾美耳球虫感染率显著高于雄性(P<0.05)。年龄≤6月龄的绵羊和山羊球虫病发生率明显高于年龄大于6月龄但小于1周岁的绵羊和山羊,差异有统计学意义(P<0.05)。棚户饲养与露天放牧的动物球虫病患病率差异有统计学意义(P<0.05)。低BCS动物球虫病患病率显著高于健康动物(P<0.05)。艾美耳虫感染率与粪便评分有显著相关性(P<0.05)。球虫病发病率以8月最高,10月最低。绵羊的感染率最高(56.78%),其次为大腹棘球绦虫(47.23%)、细小棘球绦虫(35.67%)、复杂棘球绦虫(30.15%)、山羊棘球绦虫(26.63%)和苍白棘球绦虫(19.09%)。在山羊中,最常见的艾美耳球虫属为尼纳科利亚基莫氏艾美耳球虫(68.86%),其次为阿利耶氏艾美耳球虫(59.88%)、阿洛伊氏艾美耳球虫(53.29%)、辣椒艾美耳球虫(46.70%)和hirci艾美耳球虫(22.15%)。由此可见,不同艾美耳球虫属在研究地区的流行具有不同的危险因素,研究地区球虫病的发病率受各种危险因素的影响。
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引用次数: 0
Adverse Effects of COVID-19 in Patients with Age Associated Diseases: A Mini Review COVID-19在年龄相关疾病患者中的不良反应:一项小型综述
Pub Date : 2021-12-23 DOI: 10.54692/lgujls.2021.0504189
Humaira Niamat, Afeefa Chaudhry
The world is currently suffering from a pandemic called COVID- 19 caused by the SARS-CoV-2 extreme acute respiratory syndrome coronavirus, first identified on December 31, 2019 in Wuhan, Hubei Province, China. In this review, the main focus is on the individuals infected with coronavirus while suffering from various age associated diseases such as hypertension, diabetes, obesity, and coronary heart diseases. The risk of complications such as Adult Respiratory Distress Syndrome and multi-organ failure is higher for coronavirus patients with diabetes. Depending on the global region, 20–50% of patients who were COVID positive had diabetes. Moreover, 30% of the COVID-19 patients were found with hypertension. Among COVID patients of age 50 and above, hypertension was observed as one of the most common comorbidities with increased rate of hospitalization and death. This short review highlights the basics of corona viruses, focusing on COVID-19 as well as their effects on people with age associated diseases.
目前,世界正在遭受由SARS-CoV-2极端急性呼吸综合征冠状病毒引起的COVID- 19大流行,该病毒于2019年12月31日首次在中国湖北省武汉市被发现。本综述主要关注冠状病毒感染者同时患有各种年龄相关疾病,如高血压、糖尿病、肥胖和冠心病。冠状病毒合并糖尿病患者出现成人呼吸窘迫综合征和多器官衰竭等并发症的风险更高。根据全球地区的不同,20% - 50%的COVID阳性患者患有糖尿病。此外,30%的新冠肺炎患者发现高血压。在50岁及以上的COVID患者中,高血压是最常见的合并症之一,住院率和死亡率均增加。这篇简短的综述重点介绍了冠状病毒的基础知识,重点介绍了COVID-19及其对年龄相关疾病患者的影响。
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引用次数: 0
Prevalence of Diabetes and Hypertension in Young females of Lahore College for Women University, Lahore 拉合尔女子大学年轻女性糖尿病和高血压患病率
Pub Date : 2021-12-23 DOI: 10.54692/lgujls.2021.0504185
S. Sharif, Kashaful Frasat, S. Naz, Muhammad Saqib, Rabia Maqbool
Diabetes and hypertension are non-communicable diseases. Diabetes is a significant cause of early death and debility globally. The objective of the present study is to find out the percentage incidence of diabetes and hypertension in young females of Lahore College for Women University Jail Road, Lahore. This cross-sectional study was conducted, January 2017 to June 2017. It was included 200 subjects. The average age of the population under study was 20 ± 0.17 years. About 4.5% (n=9) of the population was pre-diabetic and all were obese. While, 36% (n=73) of population was suffering from prehypertension and 5% (n=10) with hypertension. Among a total of 83 subjects with elevated systolic blood pressure (SBP), 41 were overweight and obese. According to diastolic blood pressure (DBP) 7% (n=14) of the population was suffering from pre-hypertension and 6% (n=12) with hypertension. 26 subjects had elevated diastolic blood pressure and among these, 20 subjects were overweight and obese. The whole population is divided among 4 groups according to the age groups. Body mass index was moreprevalent in the age group 25-27 years. It is stated that overweight and obesity are strongly associated with diabetes and hypertension. It was concluded that increased BMI was the main predictor of diabetes and hypertension. However no diabetic patient were found in population and the prevalence of pre-diabetic subjects were 4.5 % and according to SBP and DBP 5% and 6 % of the population were hypertensive.
糖尿病和高血压是非传染性疾病。糖尿病是全球早期死亡和衰弱的一个重要原因。本研究的目的是了解拉合尔女子大学监狱路拉合尔学院年轻女性糖尿病和高血压的发病率百分比。这项横断面研究于2017年1月至2017年6月进行。共纳入200名受试者。研究人群的平均年龄为20±0.17岁。约4.5% (n=9)的人群为糖尿病前期,且均为肥胖。36% (n=73)的人群存在高血压前期,5% (n=10)的人群存在高血压。在83例收缩压升高的受试者中,41例超重和肥胖。根据舒张压(DBP), 7% (n=14)的人群患有高血压前期,6% (n=12)的人群患有高血压。26名受试者舒张压升高,其中20名受试者超重和肥胖。全体人口按年龄组分为4组。体重指数在25-27岁年龄组中更为普遍。研究表明,超重和肥胖与糖尿病和高血压密切相关。由此得出结论,BMI升高是糖尿病和高血压的主要预测指标。然而,人群中未发现糖尿病患者,糖尿病前期患病率为4.5%,根据收缩压和舒张压,5%和6%的人群患有高血压。
{"title":"Prevalence of Diabetes and Hypertension in Young females of Lahore College for Women University, Lahore","authors":"S. Sharif, Kashaful Frasat, S. Naz, Muhammad Saqib, Rabia Maqbool","doi":"10.54692/lgujls.2021.0504185","DOIUrl":"https://doi.org/10.54692/lgujls.2021.0504185","url":null,"abstract":"Diabetes and hypertension are non-communicable diseases. Diabetes is a significant cause of early death and debility globally. The objective of the present study is to find out the percentage incidence of diabetes and hypertension in young females of Lahore College for Women University Jail Road, Lahore. This cross-sectional study was conducted, January 2017 to June 2017. It was included 200 subjects. The average age of the population under study was 20 ± 0.17 years. About 4.5% (n=9) of the population was pre-diabetic and all were obese. While, 36% (n=73) of population was suffering from prehypertension and 5% (n=10) with hypertension. Among a total of 83 subjects with elevated systolic blood pressure (SBP), 41 were overweight and obese. According to diastolic blood pressure (DBP) 7% (n=14) of the population was suffering from pre-hypertension and 6% (n=12) with hypertension. 26 subjects had elevated diastolic blood pressure and among these, 20 subjects were overweight and obese. The whole population is divided among 4 groups according to the age groups. Body mass index was moreprevalent in the age group 25-27 years. It is stated that overweight and obesity are strongly associated with diabetes and hypertension. It was concluded that increased BMI was the main predictor of diabetes and hypertension. However no diabetic patient were found in population and the prevalence of pre-diabetic subjects were 4.5 % and according to SBP and DBP 5% and 6 % of the population were hypertensive.","PeriodicalId":148827,"journal":{"name":"Lahore Garrison University Journal of Life Sciences","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131513126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Knowledge, Belief, and Practices Regarding Cirrhosis among the Students of the University of Lahore 拉合尔大学学生关于肝硬化的知识、信念和行为评估
Pub Date : 2021-12-23 DOI: 10.54692/lgujls.2021.0504184
Zarmeena Mehmood, Hadia Tariq, N. Kiran, Saira Batool, Khansa Zaib Mughal, S. Farooq, B. Rizwan
Cirrhosis is a liver injury, which leads to portal hypertension, hepatic encephalopathy, ascites, and end-stage liver disease. The study aimed to explore how much students know about liver cirrhosis and its complexity. The crosssectional study was conducted on university students in the year 2020. A selfstructured questionnaire was used in this study. It was divided into three portions, i.e., knowledge-related questions, belief-related questions and practice-related questions. Fifty-eight studentsparticipated in this study. 34.3% of students knew about the term cirrhosis, 55.2% knew about the causes of cirrhosis, 7.1% were not aware of its complications, 62.1% of students knew that dysphagia is the leading cause of malnutrition in cirrhosis, and 44.8% knew that hepatic encephalopathy leads to coma. Additionally, 46.6% believed that end-stage liver disease and cirrhosis are the same, and 77.6% believed that jaundice leads to liver disease. Furthermore, 36.2% had previously participated in a nutrition education program related to hepatic diseases, and 24.1% recommended Child-Pugh score to cirrhotic patients to assess liver function. Conclusively, some students had necessary information on liver cirrhosis, whereas some did not know about it. Moreover, the practices of the students were not according to the knowledge they had. As a health professional, the students who do not know cirrhosis well will inefficiently deal with the patients suffering from cirrhosis.
肝硬化是一种肝损伤,可导致门脉高压、肝性脑病、腹水和终末期肝病。这项研究旨在探索学生对肝硬化及其复杂性的了解程度。横断面研究是在2020年对大学生进行的。本研究采用自构式问卷。它分为三个部分,即知识相关问题,信念相关问题和实践相关问题。58名学生参与了这项研究。34.3%的学生知道肝硬化一词,55.2%的学生知道肝硬化的原因,7.1%的学生不知道肝硬化的并发症,62.1%的学生知道吞咽困难是肝硬化中营养不良的主要原因,44.8%的学生知道肝性脑病导致昏迷。此外,46.6%的人认为终末期肝病和肝硬化是相同的,77.6%的人认为黄疸导致肝脏疾病。此外,36.2%的人以前参加过与肝病相关的营养教育计划,24.1%的人向肝硬化患者推荐Child-Pugh评分来评估肝功能。最后,一些学生对肝硬化有必要的了解,而一些学生不知道。此外,学生的实践并不是根据他们所拥有的知识。作为一名卫生专业人员,不了解肝硬化的学生将无法有效地应对肝硬化患者。
{"title":"Assessment of Knowledge, Belief, and Practices Regarding Cirrhosis among the Students of the University of Lahore","authors":"Zarmeena Mehmood, Hadia Tariq, N. Kiran, Saira Batool, Khansa Zaib Mughal, S. Farooq, B. Rizwan","doi":"10.54692/lgujls.2021.0504184","DOIUrl":"https://doi.org/10.54692/lgujls.2021.0504184","url":null,"abstract":"Cirrhosis is a liver injury, which leads to portal hypertension, hepatic encephalopathy, ascites, and end-stage liver disease. The study aimed to explore how much students know about liver cirrhosis and its complexity. The crosssectional study was conducted on university students in the year 2020. A selfstructured questionnaire was used in this study. It was divided into three portions, i.e., knowledge-related questions, belief-related questions and practice-related questions. Fifty-eight studentsparticipated in this study. 34.3% of students knew about the term cirrhosis, 55.2% knew about the causes of cirrhosis, 7.1% were not aware of its complications, 62.1% of students knew that dysphagia is the leading cause of malnutrition in cirrhosis, and 44.8% knew that hepatic encephalopathy leads to coma. Additionally, 46.6% believed that end-stage liver disease and cirrhosis are the same, and 77.6% believed that jaundice leads to liver disease. Furthermore, 36.2% had previously participated in a nutrition education program related to hepatic diseases, and 24.1% recommended Child-Pugh score to cirrhotic patients to assess liver function. Conclusively, some students had necessary information on liver cirrhosis, whereas some did not know about it. Moreover, the practices of the students were not according to the knowledge they had. As a health professional, the students who do not know cirrhosis well will inefficiently deal with the patients suffering from cirrhosis.","PeriodicalId":148827,"journal":{"name":"Lahore Garrison University Journal of Life Sciences","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132022000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phytochemical Composition of Mint (Mentha), its Nutritional and Pharmacological Potential 薄荷(Mentha)的植物化学成分及其营养和药理潜力
Pub Date : 2021-12-23 DOI: 10.54692/lgujls.2021.0504188
S. Hussain, Maria Tanvir, M. Ahmad, K. Munawar
Current studies were made to investigate the phytochemical, nutritional and medicinal importance of the mint plant. Mint plantgenerally contains menthol (40.7%), menthone (23.4%), methylacetate (0.7-23%), eucalyptol (1-13%), carveol (0.31%), piperitone (3.20%) and fiber (1.75%±0.1). The important nutritional contents include iron (0.262%), calcium (0.158%), phytic acid (0.00092%), proteins (0.6%), vitamin E (9.89±0.15%), ascorbic acid (0.96±0.06%) and axerophthol (0.426±0.05%). Mint is one of most familiar plants that iswidely cultivated throughout the planet. The plant finds immense importance in the pharmaceutical and food industry. The plant also finds colossal applicationsas antimicrobial,n anti-oxidant, anti-bacterial and anti-inflammatory agent. The promising capability of the plant towards the field of therapeutic drugs development has been widely investigated.
目前对薄荷植物的植物化学、营养和药用价值进行了研究。薄荷植物一般含有薄荷醇(40.7%)、薄荷酮(23.4%)、乙酸甲酯(0.7-23%)、桉叶油醇(1-13%)、卡维罗醇(0.31%)、胡椒酮(3.20%)和纤维(1.75%±0.1)。主要营养成分为铁(0.262%)、钙(0.158%)、植酸(0.00092%)、蛋白质(0.6%)、维生素E(9.89±0.15%)、抗坏血酸(0.96±0.06%)和干草酚(0.426±0.05%)。薄荷是最熟悉的植物之一,在地球上广泛种植。这种植物在制药和食品工业中具有巨大的重要性。这种植物还被广泛应用于抗菌、抗氧化、抗菌和抗炎剂。该植物在治疗药物开发领域的潜力已被广泛研究。
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引用次数: 3
Association of Obesity with Covid-19 and Nutrition Perspective 肥胖与Covid-19的关系和营养观点
Pub Date : 2021-12-23 DOI: 10.54692/lgujls.2021.0504191
S. Khalid, Manal Fida, Hiba Irfan, Misbah Arshad, M. Imran, Noor Fatima, Muntaha Khalid, Bisma Javaid, Kainat Sadiq, M. Rashid, Esha Tariq
COVID-19 is a disease that cause respiratory illness due to novel corona virus. It was reported by WHO on December 31,2019 for the first time. The outbreak of this disease started from Wuhan city, China. Now COVID-19 has been declared as a universal pandemic. The epidemiological outcomes of COVID-2019 have not been completely understood yet. The present review tried to find association between obesity and COVID-19, also the extent of severity it may cause in the disease.
COVID-19是一种由新型冠状病毒引起的呼吸道疾病。世卫组织于2019年12月31日首次报告。该疾病的暴发始于中国武汉市。现在,COVID-19已被宣布为全球大流行。2019年冠状病毒病的流行病学结果尚未完全了解。本综述试图找出肥胖与COVID-19之间的联系,以及它可能导致疾病的严重程度。
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引用次数: 0
Antibiotic Resistance Profiling of Pseudomonas Species Isolated from Cloacal Swab of Domestic Pigeons 家鸽粪拭子假单胞菌的耐药性分析
Pub Date : 2021-07-12 DOI: 10.54692/lgujls.2021.0503173
Muhammad Ahmed Azeem
Antibiotics are used to treat a number of bacterial infections. However, overuse or misuse of antibiotics has raised serious concerns against antibioticresistance amongst bacteria. Hence, antibiotics are becoming inefficient in treating bacterial infections leading to an increase in mortality rate worldwide. The domestic animals especially birds are a major source of transmission of antibiotic resistant bacteria in human through excrement and cause bacterial diseases in human. The aim of the present study was to assess the efficacy of different antibiotics prior to their prescription as a measure to prevent antibiotic resistance in bacteria. For this 120 cloacal swab samples were collected from the domestic pigeons of District Narowal to isolate Pseudomonas sp. and assess the efficacy of different antibiotics prior to their prescription as a measure to prevent antibiotic resistance in bacteria. Antibacterial activities were evaluated by performing antibiotic susceptibility pattern of Pseudomonas isolates against 18 commercially available antibiotic discs [Trimethoprime (TMP), Clarithromycin (CLR), Gentamicin (GEN), Chloramphenicol (C), Ampicillin (AM), Streptomycin (S), Kanamycin (K), Nitrofurantoin (F), Amoxicillin (AX), Tazobactam (TPZ), Imipenem (IPM), Meropenem (MEM), Levofloxacin (LEV), Nalidixic acid (NA), Ceftriaxone (CRO), Amikacin (AK), Tetracycline (TE) and Ciprofloxacin (CIP)] by using Kirby-Bauer disc diffusion method. Amongst these antibiotics, notably Pseudomonas sp. showed highest sensitivity to Clarithromycin (93.94%), Ampicillin (100%), Amikacin (93%) and Nalidixic (100%). This study established a general antibiotic resistance pattern of commercially used different antibiotics for commonly encountered clinical isolates. Moreover, antibiotics susceptibility tests (AST) should be carried out prior to prescribing antibiotics to the patient. Additionally, the antibacterial activities of local clinical isolates and change in bacteriological profile due to indiscriminate use of antibiotics associated with appearance of multiple drug resistant strains should be evaluated. It was concluded that preventive measure and their implementation is quite necessary to control antibiotic resistance and domestic pigeons can be a carrier of Pseudomonas species and can transmit through their fecal material to humans and other animals.
抗生素被用来治疗许多细菌感染。然而,过度使用或滥用抗生素已经引起了对细菌抗生素耐药性的严重关注。因此,抗生素在治疗细菌感染方面变得低效,导致全球死亡率上升。家畜特别是禽鸟是人类通过粪便传播耐药细菌的主要来源,并引起人类细菌性疾病。本研究的目的是评估不同抗生素在处方前的疗效,作为防止细菌耐药的措施。为此,从Narowal地区的家鸽中采集120份粪拭子样本,分离假单胞菌,并在处方前评估不同抗生素的疗效,作为预防细菌耐药的措施。通过对18种市售抗生素片[甲氧嘧啶(TMP)、克拉霉素(CLR)、庆大霉素(GEN)、氯霉素(C)、氨苄西林(AM)、链霉素(S)、卡那霉素(K)、呋喃妥英(F)、阿莫西林(AX)、他唑巴坦(TPZ)、亚胺培南(IPM)、美罗培南(MEM)、左氧氟沙星(LEV)、萘啶酸(NA)、头孢曲松(CRO)、阿米卡星(AK)、四环素(TE)和环丙沙星(CIP)用Kirby-Bauer圆盘扩散法测定。其中,假单胞菌对克拉霉素(93.94%)、氨苄西林(100%)、阿米卡星(93%)和那利地西奇(100%)的敏感性最高。本研究建立了常见临床分离株商用不同抗生素的一般耐药模式。此外,在给患者开抗生素处方之前,应进行抗生素敏感性试验(AST)。此外,应评估当地临床分离株的抗菌活性以及因滥用抗生素而导致的细菌学特征的变化,这些变化与多重耐药菌株的出现有关。结论:预防措施的实施是控制抗生素耐药性的必要措施,家鸽可能是假单胞菌的携带者,并可通过其粪便传播给人类和其他动物。
{"title":"Antibiotic Resistance Profiling of Pseudomonas Species Isolated from Cloacal Swab of Domestic Pigeons","authors":"Muhammad Ahmed Azeem","doi":"10.54692/lgujls.2021.0503173","DOIUrl":"https://doi.org/10.54692/lgujls.2021.0503173","url":null,"abstract":"Antibiotics are used to treat a number of bacterial infections. However, overuse or misuse of antibiotics has raised serious concerns against antibioticresistance amongst bacteria. Hence, antibiotics are becoming inefficient in treating bacterial infections leading to an increase in mortality rate worldwide. The domestic animals especially birds are a major source of transmission of antibiotic resistant bacteria in human through excrement and cause bacterial diseases in human. The aim of the present study was to assess the efficacy of different antibiotics prior to their prescription as a measure to prevent antibiotic resistance in bacteria. For this 120 cloacal swab samples were collected from the domestic pigeons of District Narowal to isolate Pseudomonas sp. and assess the efficacy of different antibiotics prior to their prescription as a measure to prevent antibiotic resistance in bacteria. Antibacterial activities were evaluated by performing antibiotic susceptibility pattern of Pseudomonas isolates against 18 commercially available antibiotic discs [Trimethoprime (TMP), Clarithromycin (CLR), Gentamicin (GEN), Chloramphenicol (C), Ampicillin (AM), Streptomycin (S), Kanamycin (K), Nitrofurantoin (F), Amoxicillin (AX), Tazobactam (TPZ), Imipenem (IPM), Meropenem (MEM), Levofloxacin (LEV), Nalidixic acid (NA), Ceftriaxone (CRO), Amikacin (AK), Tetracycline (TE) and Ciprofloxacin (CIP)] by using Kirby-Bauer disc diffusion method. Amongst these antibiotics, notably Pseudomonas sp. showed highest sensitivity to Clarithromycin (93.94%), Ampicillin (100%), Amikacin (93%) and Nalidixic (100%). This study established a general antibiotic resistance pattern of commercially used different antibiotics for commonly encountered clinical isolates. Moreover, antibiotics susceptibility tests (AST) should be carried out prior to prescribing antibiotics to the patient. Additionally, the antibacterial activities of local clinical isolates and change in bacteriological profile due to indiscriminate use of antibiotics associated with appearance of multiple drug resistant strains should be evaluated. It was concluded that preventive measure and their implementation is quite necessary to control antibiotic resistance and domestic pigeons can be a carrier of Pseudomonas species and can transmit through their fecal material to humans and other animals.","PeriodicalId":148827,"journal":{"name":"Lahore Garrison University Journal of Life Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125626121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Awareness Regarding Hygienic Practices in Tuberculosis Patients of Sir Ganga Ram Hospital, Lahore 拉合尔恒河拉姆爵士医院肺结核病人的卫生习惯意识
Pub Date : 2021-07-12 DOI: 10.54692/lgujls.2021.0503176
Muniba Tariq, Misbah Arshad, Maimoona Ashfaq, Hafsa Kamran, T. Faridi, S. Khalid
Worldwide, in a working-age population the tuberculosis poses a vital health care load among young adults. As the prevalence of tuberculosis increased, therate of morbidity and mortality also increased. The objective of the study was to assess the awareness regarding hygienic practices among tuberculosis patients visiting Tertiary Care Hospital Lahore. A cross-sectional study was carried out at the chest department of Sir Ganga Ram Hospital, Lahore during November-2018 to January- 2019.A sample of 100 samples of tuberculosis patients was selected through nonprobability convenient sampling technique. Patients were assessed through pre-tested questionnaire. SPSS version 21.0 was used for data analysis. Among 100 participants, 55 patients were female and 45 patients were male. The prevalence of extra pulmonary TB is more in female 33% than male 21%. The mean age of the patients was 35 years. 63% TB patients cannot covered their face with mask when they cough or sneeze; 37 % TB patients had covered their faces with mask when they cough or sneeze. Total 79% TB patient’s houses were good ventilated while 21% TB patient’s houses or rooms were not ventilated. It was concluded that an increased family size, poor hygienic environment and low socioeconomic status were major determinants of tuberculosis
在世界范围内,在工作年龄人口中,结核病对年轻人造成了重大的卫生保健负担。随着结核病流行率的增加,发病率和死亡率也在增加。本研究的目的是评估在拉合尔三级保健医院就诊的肺结核病人对卫生习惯的认识。2018年11月至2019年1月期间,在拉合尔的恒河公羊爵士医院胸科进行了一项横断面研究。采用非概率方便抽样技术,选取100例结核病患者样本。通过预测问卷对患者进行评估。采用SPSS 21.0版本进行数据分析。100名参与者中,女性55例,男性45例。女性外肺结核患病率为33%,高于男性21%。患者的平均年龄为35岁。63%的结核病患者在咳嗽或打喷嚏时不能用口罩遮挡面部;37%的结核病患者咳嗽或打喷嚏时戴口罩。共有79%的结核病患者的房屋通风良好,21%的结核病患者的房屋或房间不通风。结论是,家庭规模扩大、卫生环境差和社会经济地位低是结核病的主要决定因素
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Lahore Garrison University Journal of Life Sciences
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