Pub Date : 2026-02-10DOI: 10.1016/j.jaci.2025.12.865
Erin Steinbach, Katelyn Clough, Ismael Gomez-Martinez, Gabrielle Cannon, Nathan VanLandingham, Benjamin Huan, Zena Khaled, Sophie Kennedy, Valerie Gartner, Matthew Schaner, Maria Chettoor, Grace Lian, Gwen Lau, Sophie Silverstein, Caroline Beasley, David Weaver, Brady Furey, Sabina Mir, Matthew Egberg, Austin Hepperla, A. Wesley Burks, Terrence Furey, Shehzad Sheikh
{"title":"Paneth Cell-Derived Lysozyme Is Deficient In Peanut Allergy","authors":"Erin Steinbach, Katelyn Clough, Ismael Gomez-Martinez, Gabrielle Cannon, Nathan VanLandingham, Benjamin Huan, Zena Khaled, Sophie Kennedy, Valerie Gartner, Matthew Schaner, Maria Chettoor, Grace Lian, Gwen Lau, Sophie Silverstein, Caroline Beasley, David Weaver, Brady Furey, Sabina Mir, Matthew Egberg, Austin Hepperla, A. Wesley Burks, Terrence Furey, Shehzad Sheikh","doi":"10.1016/j.jaci.2025.12.865","DOIUrl":"https://doi.org/10.1016/j.jaci.2025.12.865","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":"21 1","pages":""},"PeriodicalIF":14.2,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146152879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-10DOI: 10.1016/j.jaci.2025.12.400
Punam Rawal, Alfred Lee, Diego Gamboa, Heather Stacy, Keith Graver, Ingeborg Langohr, Hong Ma, Colleen Maloney, Caroline Morel, Dinesh Bangari, Adnan Khan, Alexandra Hicks, Mithilesh Jha
{"title":"Elucidating the Mechanisms Underpinning Eosinophilic Esophagitis","authors":"Punam Rawal, Alfred Lee, Diego Gamboa, Heather Stacy, Keith Graver, Ingeborg Langohr, Hong Ma, Colleen Maloney, Caroline Morel, Dinesh Bangari, Adnan Khan, Alexandra Hicks, Mithilesh Jha","doi":"10.1016/j.jaci.2025.12.400","DOIUrl":"https://doi.org/10.1016/j.jaci.2025.12.400","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":"1 1","pages":""},"PeriodicalIF":14.2,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146152882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-09DOI: 10.1016/j.jaci.2026.01.012
Wan Chi Chang, Lisa J Martin, Latha Satish, Lindsey Williams, Mindy Hammonds, Seth Jenkins, Garrett Osswald, Julie Caldwell, Marc E Rothenberg, Gurjit K Khurana Hershey, Jocelyn M Biagini
{"title":"Longitudinal enrichment of eosinophilic esophagitis in children with AD: The MPAACH cohort.","authors":"Wan Chi Chang, Lisa J Martin, Latha Satish, Lindsey Williams, Mindy Hammonds, Seth Jenkins, Garrett Osswald, Julie Caldwell, Marc E Rothenberg, Gurjit K Khurana Hershey, Jocelyn M Biagini","doi":"10.1016/j.jaci.2026.01.012","DOIUrl":"10.1016/j.jaci.2026.01.012","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":" ","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-09DOI: 10.1016/j.jaci.2026.01.007
Georgia Wells, Sophie Grice, Joscelyn Sarsby, Dean Naisbitt, Xiaoli Meng
{"title":"Covalent binding of flucloxacillin to 14-3-3 proteins promotes naive T-cell activation.","authors":"Georgia Wells, Sophie Grice, Joscelyn Sarsby, Dean Naisbitt, Xiaoli Meng","doi":"10.1016/j.jaci.2026.01.007","DOIUrl":"https://doi.org/10.1016/j.jaci.2026.01.007","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":" ","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-09DOI: 10.1016/j.jaci.2025.12.1014
Isabel María Jiménez-Sánchez, Raquel Jurado-Escobar, Inmaculada Doña, Rocío Sáenz de Santa María, Rafael Núñez, José Triano-Cornejo, Juan J Cortés-Collado, José J Laguna, David Loli-Ausejo, Antonio Vega-Rioja, José D López-Sánchez, María J Torres, José A Cornejo-García
{"title":"Reply.","authors":"Isabel María Jiménez-Sánchez, Raquel Jurado-Escobar, Inmaculada Doña, Rocío Sáenz de Santa María, Rafael Núñez, José Triano-Cornejo, Juan J Cortés-Collado, José J Laguna, David Loli-Ausejo, Antonio Vega-Rioja, José D López-Sánchez, María J Torres, José A Cornejo-García","doi":"10.1016/j.jaci.2025.12.1014","DOIUrl":"https://doi.org/10.1016/j.jaci.2025.12.1014","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":" ","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-09DOI: 10.1016/j.jaci.2026.01.014
Baodong Wang, Jiayuan Huang, Zhiyun Chen
{"title":"Beyond association: Defining the hybrid endotype and environmental interplay in NSAID-induced urticaria/angioedema.","authors":"Baodong Wang, Jiayuan Huang, Zhiyun Chen","doi":"10.1016/j.jaci.2026.01.014","DOIUrl":"https://doi.org/10.1016/j.jaci.2026.01.014","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":" ","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146142662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-05DOI: 10.1016/j.jaci.2026.01.024
Leonardo M. Ologundudu, Melanie M. Wong, Nazmul Islam, Daniel G. Rayner, Alexandro W.L. Chu, Mark Loeb, Katherine Rivera-Spoljaric, Bradley Chipps, Kaharu Sumino, John Oppenheimer, Sharmilee M. Nyenhuis, Elliot Israel, Flavia Hoyte, Tamara T. Perry, Ellen McCabe, Valerie G. Press, Susana Rangel, Gordon H. Guyatt, Lindsay E. Shade, Paul M. O’Byrne, Hilarry Orr, Dia Sue-Wah-Sing, Angel Melendez, Tonya Winders, Donna D. Gardner, Kathyrn Przywara, Giselle Mosnaim, Leonard B. Bacharier, Matthew A. Rank, Derek K. Chu
{"title":"Macrolides for asthma: a systematic review and meta-analysis of randomized trials","authors":"Leonardo M. Ologundudu, Melanie M. Wong, Nazmul Islam, Daniel G. Rayner, Alexandro W.L. Chu, Mark Loeb, Katherine Rivera-Spoljaric, Bradley Chipps, Kaharu Sumino, John Oppenheimer, Sharmilee M. Nyenhuis, Elliot Israel, Flavia Hoyte, Tamara T. Perry, Ellen McCabe, Valerie G. Press, Susana Rangel, Gordon H. Guyatt, Lindsay E. Shade, Paul M. O’Byrne, Hilarry Orr, Dia Sue-Wah-Sing, Angel Melendez, Tonya Winders, Donna D. Gardner, Kathyrn Przywara, Giselle Mosnaim, Leonard B. Bacharier, Matthew A. Rank, Derek K. Chu","doi":"10.1016/j.jaci.2026.01.024","DOIUrl":"https://doi.org/10.1016/j.jaci.2026.01.024","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":"95 1","pages":""},"PeriodicalIF":14.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-05DOI: 10.1016/j.jaci.2026.01.026
Amer Al-Musa, Craig Platt, Megan Elkins, Tanya Novak, Brian Woods, Aleksandra Bourdine, Logan Magin, Brittany G. Craiglow, Margaret M. Newhams, Michele Kong, Adrienne Randolph, Janet Chou
{"title":"Heterozygous variants in DOCK2 leading to susceptibility to viral illnesses","authors":"Amer Al-Musa, Craig Platt, Megan Elkins, Tanya Novak, Brian Woods, Aleksandra Bourdine, Logan Magin, Brittany G. Craiglow, Margaret M. Newhams, Michele Kong, Adrienne Randolph, Janet Chou","doi":"10.1016/j.jaci.2026.01.026","DOIUrl":"https://doi.org/10.1016/j.jaci.2026.01.026","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":"27 1","pages":""},"PeriodicalIF":14.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-05DOI: 10.1016/j.jaci.2026.01.023
Elizabeth G. Schmitz, Alexander J. Paul, Rajarshi Ghosh, Nermina Saucier, Ana Leticia Kolicheski, Samuel I. Risma, Kristen P. McDaniels, Michelle Liu, Katie L. Lewis, Adriana A. de Jesus, Sara Alehashemi, Catrina C. Fronick, David Stein, Daniela Dominguez, Linda Hiraki, Jessica H. Lee, Stephanie Norman, Christine R. Peng, Brant R. Ward, Leah Pettiford, Anna Platt, Monica G. Lawrence, Joseph Rocco, Waleed AL-Herz, Christa S. Zerbe, T.Prescott Atkinson, Xiao P. Peng, Eric J. Allenspach, David P. Hoytema van Konijnenburg, Craig D. Platt, Megan Elkins, Jolan E. Walter, Jack J. Bleesing, Amy Klion, Ramya Ramaswami, Gulbu Uzel, Michail S. Lionakis, Dilan Dissanayake, Helen C. Su, Irene Cortese, Ivan J. Fuss, Jenna R.E. Bergerson, Lesia Dropulic, Irini Sereti, Andrea Lisco, Yuval Itan, Joshua D. Milner, Dusan Bogunovic, Raphaela Goldbach-Mansky, V.Koneti Rao, Ottavia M. Delmonte, Luigi D. Notarangelo, Michael D. Keller, Jessica Durkee-Shock, Jeffrey I. Cohen, Morgan N. Similuk, Steven M. Holland, Malachi Griffith, Obi L. Griffith, Tiphanie P. Vogel, Scott Canna, Alexandra F. Freeman, Magdalena A. Walkiewicz, Megan A. Cooper
{"title":"Targeted deep sequencing identifies mosaicism in patients with immune dysregulation","authors":"Elizabeth G. Schmitz, Alexander J. Paul, Rajarshi Ghosh, Nermina Saucier, Ana Leticia Kolicheski, Samuel I. Risma, Kristen P. McDaniels, Michelle Liu, Katie L. Lewis, Adriana A. de Jesus, Sara Alehashemi, Catrina C. Fronick, David Stein, Daniela Dominguez, Linda Hiraki, Jessica H. Lee, Stephanie Norman, Christine R. Peng, Brant R. Ward, Leah Pettiford, Anna Platt, Monica G. Lawrence, Joseph Rocco, Waleed AL-Herz, Christa S. Zerbe, T.Prescott Atkinson, Xiao P. Peng, Eric J. Allenspach, David P. Hoytema van Konijnenburg, Craig D. Platt, Megan Elkins, Jolan E. Walter, Jack J. Bleesing, Amy Klion, Ramya Ramaswami, Gulbu Uzel, Michail S. Lionakis, Dilan Dissanayake, Helen C. Su, Irene Cortese, Ivan J. Fuss, Jenna R.E. Bergerson, Lesia Dropulic, Irini Sereti, Andrea Lisco, Yuval Itan, Joshua D. Milner, Dusan Bogunovic, Raphaela Goldbach-Mansky, V.Koneti Rao, Ottavia M. Delmonte, Luigi D. Notarangelo, Michael D. Keller, Jessica Durkee-Shock, Jeffrey I. Cohen, Morgan N. Similuk, Steven M. Holland, Malachi Griffith, Obi L. Griffith, Tiphanie P. Vogel, Scott Canna, Alexandra F. Freeman, Magdalena A. Walkiewicz, Megan A. Cooper","doi":"10.1016/j.jaci.2026.01.023","DOIUrl":"https://doi.org/10.1016/j.jaci.2026.01.023","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":"33 1","pages":""},"PeriodicalIF":14.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146134409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-03DOI: 10.1016/j.jaci.2026.01.021
Michael T. Lam, Amrita Basu, Kailey E. Brodeur, Courtney LeSon, Evan Hsu, Musaab A. Alhezam, Rachel Weng, Seigo Okada, Casey A. Rimland, Jian Yue, Xiao P. Peng, Christian Wysocki, Anusha Ramanathan, Zhengping Huang, Milena M. Andzelm, Connie L. Jiang, Holly Wobma, Joyce C. Chang, Janet Chou, Mary Beth F. Son, Craig D. Platt, Lauren A. Henderson, Roshini S. Abraham, Pui Y. Lee
{"title":"A clinically validated assay for rapid determination of type I and type II interferon activity in systemic inflammatory diseases","authors":"Michael T. Lam, Amrita Basu, Kailey E. Brodeur, Courtney LeSon, Evan Hsu, Musaab A. Alhezam, Rachel Weng, Seigo Okada, Casey A. Rimland, Jian Yue, Xiao P. Peng, Christian Wysocki, Anusha Ramanathan, Zhengping Huang, Milena M. Andzelm, Connie L. Jiang, Holly Wobma, Joyce C. Chang, Janet Chou, Mary Beth F. Son, Craig D. Platt, Lauren A. Henderson, Roshini S. Abraham, Pui Y. Lee","doi":"10.1016/j.jaci.2026.01.021","DOIUrl":"https://doi.org/10.1016/j.jaci.2026.01.021","url":null,"abstract":"","PeriodicalId":14936,"journal":{"name":"Journal of Allergy and Clinical Immunology","volume":"29 1","pages":""},"PeriodicalIF":14.2,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146110549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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