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Comparative Study between Three Solutions for Cardioplegia in Pediatric Cardiac Surgery: Histidine-Tryptophan-Ketoglutarate (HTK) Solution, Blood Cardioplegia and Crystalloid (St. Thomas) Cardioplegia 组氨酸-色氨酸-酮戊二酸(HTK)溶液、血液停搏液和Crystalloid (St. Thomas)停搏液三种小儿心脏外科停搏液的比较研究
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000818
M. Elhamamsy, Hoda Hafez Bahi Eldin, Yahia Mahmoud, M. Hamed, Rana Ahmed Abdel-Ghaffar
Background: Cardioplegia is the solution used to arrest and protect the heart during aortic cross-clamping. Crystalloid and blood cardioplegia are both widely used in clinical practice. Custodial-HTK solution is an intracellular cardioplegic solution containing histidine, tryptophan and ketoglutarate. Aim: we compared the myocardial protective effects of 3 types of cardioplegia solution: The histidine–tryptophan– ketoglutarate (HTK) solution, blood and St.Thomas cardioplegia in pediatric cardiac surgery. Settings and Design: This study design was a prospective randomized controlled double blinded clinical study. Patients and Methods: 60 children aged 3-10 yrs of either sex who underwent elective cardiac surgery for acyanotic heart diseases using cardiopulmonary bypass were randomly allocated to three groups each one 20 patients: Group A received HTK cardioplegia. Group B received blood cardioplegia. Group C received St, Thomas cardioplegia. Hemodynamic parameters, duration of CPB, aortic cross clamping and the whole surgical duration, mechanical ventilation duration and the length of ICU stay were measured. Venous blood samples were collected for measurement of cardiac marker proteins (CK-MB) and troponin (t). Uses of inotropic support were also recorded. Statistical Analysis Used: one-way ANOVA test and Chi-square test were used. Results: The main findings in our results were that troponin (t) levels were not statistically significant different among the study groups except that recorded 24 h, with the highest level was in the group (B) and the lowest one in the group (C). CK-MB levels also were not statistically significant different among the study groups except that recorded after 12 h the highest one in group (C) and the lowest one in group (B). Conclusion: Single dose of cold HTK cardioplegia in pediatric cardiac surgery is as effective as multiple doses of cold blood and crystalloid (St.Thomas) cardioplegia in protecting the myocardium.
背景:在主动脉交叉夹持过程中,心脏截留是用来阻止和保护心脏的解决方案。晶体截止剂和血液截止剂均在临床应用广泛。Custodial-HTK溶液是一种含有组氨酸、色氨酸和酮戊二酸的细胞内心脏截瘫溶液。目的:比较组氨酸-色氨酸-酮戊二酸(HTK)溶液、血液和圣托马斯停搏液3种停搏液在小儿心脏手术中的心肌保护作用。背景和设计:本研究设计为前瞻性随机对照双盲临床研究。患者和方法:60例3-10岁的儿童,均为择期行体外循环治疗无氰性心脏病的心脏手术患者,随机分为三组,每组20例:A组采用HTK停搏。B组接受血液停搏。C组采用St, Thomas心脏停搏术。测量血流动力学参数、CPB时间、主动脉交叉夹持时间、手术总时间、机械通气时间、ICU住院时间。静脉血样本用于测量心脏标记蛋白(CK-MB)和肌钙蛋白(t)。同时记录肌力支持的使用情况。统计学方法:采用单因素方差分析和卡方检验。结果:我们的研究结果主要发现:各组间肌钙蛋白(t)水平除24 h记录外无统计学差异,其中B组最高,C组最低;CK-MB水平除12 h记录后C组最高,B组最低外,各组间差异无统计学意义。小儿心脏手术中单剂量冷HTK停搏与多剂量冷血和晶体(St.Thomas)停搏对心肌的保护效果相同。
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引用次数: 4
Anaesthetic Management of Traumatic Brain Injury in Pregnancy for Emergency Craniotomy 急诊开颅术中妊娠外伤性脑损伤的麻醉处理
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000808
Monika Dabgotra, J. Jacob, M. George, M. Mathew
Management of head injury requiring emergency craniotomy in a parturient is indeed challenging. Unexpectedly mild head injury can threaten the life of mother or fetus. A multidisciplinary approach to management which is individualized according to severity of injury and gestational age is appropriate. Neuroanaesthetic approach should strive to provide balance between therapy for mother and risks for fetus. Evidence based recommendations from randomized controlled trials to manage such cases is limited. We report a case of 27 year old woman in late 2nd trimester with extradural and subdural hematoma requiring urgent decompressive craniotomy. Post-operatively, she was managed for two days in the intensive care unit with regular monitoring of Fetal Heart Sound (FHS). Pregnancy continued till term with good outcome of mother and child.
需要紧急开颅的产妇头部损伤的处理确实具有挑战性。意想不到的轻微头部损伤会威胁到母亲或胎儿的生命。多学科的方法来管理,是根据损伤的严重程度和胎龄个体化是适当的。神经麻醉方法应努力在对母亲的治疗和对胎儿的风险之间提供平衡。来自随机对照试验的以证据为基础的建议是有限的。我们报告一例27岁的妇女在晚期妊娠晚期硬膜外和硬膜下血肿需要紧急减压开颅术。术后在重症监护病房进行2天监护,定期监测胎儿心音。妊娠持续至足月,母婴预后良好。
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引用次数: 1
Magnitude of Airway Problems at a University Teaching and Referral Hospital Recovery Room of Low Resource Setting-A Cross Sectional Study 低资源环境下大学教学转诊医院康复室气道问题严重程度的横断面研究
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000825
Gebremedhn Endale Gebreegziabher, H. Tawuye
Background: Airway management is a basic life-saving intervention which is used when the patient’s breathing effort is compromised due to various reasons. Postsurgical patients are at risk of developing airway problems due to co-morbidities, intraoperative complications, surgery and anaesthetic drug effects. The severity of illness, analgesic drugs like narcotics and postoperative standard of monitoring may impact on breathing process of the patients. We aimed to assess the magnitude of airway problems at the recovery room. Methods and material: Cross sectional study conducted at a referral hospital recovery room, 2014. Standardized checklist used for data collection. All patients with airway problem who admitted at the recovery room during the study period were included in the study. Descriptive statistics and Chi-square were used. Results: One hundred seventy seven patients developed airway problems over five months duration. Of these, 47.5%, 32.2%, and 20.3% patients developed mild, moderate and severe airway problems respectively. The major airway problems were desaturation (62.7%), respiratory arrest (14.7%), aspiration (18.1%), bronchospasm (3.4%) and laryngospasm (1.1%) respectively. Factors associated with severity of airway problems were ASA status (P=0.031), type of trauma (P=0.026), intraoperative analgesia (P=0.020) and type of patient (P=0.049). The interventions made were ETTI or LMA (35%) patients, nasopharyngeal airway insertion (21.5%), oral airway (14.1%), oxygen supplementation (10.2%), surgical airway (9.6%), recovery position (7.3%) and emergency airway manoeuvre (2.3%) respectively. Anaesthetists involved in airway management in 30.5% of patients. Conclusion: The magnitude of airway problem was high. We recommend the availability of well trained staff for airway management and fulfilment of basic equipments and drugs for patient monitoring and resuscitation. High airway problems are an alarm for the need for well-equipped recovery room with well trained staff, patient monitoring and resuscitation materials.
背景:气道管理是一项基本的挽救生命的干预措施,当患者的呼吸努力受到损害,由于各种原因。由于合并症、术中并发症、手术和麻醉药物的作用,术后患者有发生气道问题的风险。病情的严重程度、麻醉等镇痛药物以及术后监测的标准都可能影响患者的呼吸过程。我们的目的是评估恢复室气道问题的严重程度。方法与材料:2014年在某转诊医院康复室进行横断面研究。用于数据收集的标准化检查表。所有在研究期间入住康复室的气道问题患者都被纳入研究。采用描述性统计和卡方分析。结果:177例患者在5个月内出现气道问题。其中,47.5%、32.2%和20.3%的患者分别出现轻度、中度和重度气道问题。主要气道问题分别为去饱和(62.7%)、呼吸骤停(14.7%)、误吸(18.1%)、支气管痉挛(3.4%)和喉痉挛(1.1%)。与气道问题严重程度相关的因素有ASA状态(P=0.031)、创伤类型(P=0.026)、术中镇痛(P=0.020)和患者类型(P=0.049)。采取干预措施的患者分别为ETTI或LMA(35%)、鼻咽气道插入(21.5%)、口腔气道(14.1%)、补氧(10.2%)、手术气道(9.6%)、恢复体位(7.3%)和紧急气道操作(2.3%)。30.5%的患者有麻醉师参与气道管理。结论:患儿气道问题严重。我们建议提供训练有素的人员进行气道管理,并提供基本的设备和药物,以进行患者监测和复苏。高气道问题是一个警报,需要装备精良的恢复室,训练有素的工作人员,病人监测和复苏材料。
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引用次数: 0
Cervical Epidural Analgesia with Laryngeal Mask Airway Assisted Ventilation for Thymectomy in Myasthenia Gravis 重症肌无力患者胸腺切除术硬膜外硬膜喉罩辅助通气镇痛
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000860
Avinash Londhe, Madhu Chavan
Myasthenia gravis is a disease of great significance to the anesthesiologist, because it affects the neuromuscular junction. In this paper, we discuss the case of a 57 y. Old male patient with newly diagnosed myasthenia gravis who is scheduled for transsternal thymectomy. Anaesthesia for thymectomy in myasthenia is challenging. We have used a modern approach and have successfully done thymectomy under general anaesthesia avoiding need for intubation of trachea and most importantly avoiding use of muscle relaxant. We maintained adequate muscle relaxation with the use of inhalational agent (Sevoflurane) and anaesthetic dose of local anaesthetic through cervical epidural.
重症肌无力是一种对麻醉师意义重大的疾病,因为它影响神经肌肉连接处。在本文中,我们讨论的情况下,57岁的老年男性患者新诊断重症肌无力谁是计划经胸骨胸腺切除术。肌无力胸腺切除术的麻醉具有挑战性。我们采用现代方法,在全身麻醉下成功地完成了胸腺切除术,避免了气管插管,最重要的是避免了使用肌肉松弛剂。我们使用吸入剂(七氟醚)和经宫颈硬膜外局部麻醉剂量保持足够的肌肉松弛。
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引用次数: 0
A Randomized Controlled Trial of Intravenous and Intramuscular Ketorolac for Post-Cesarean Analgesia 子宫剖宫产后静脉注射和肌肉注射酮咯酸镇痛的随机对照试验
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000861
C. Fidkowski
Backgroundː Optimal analgesia post-cesarean delivery is essential to promote maternal recovery for the care of the newborn. Intravenous (IV) ketorolac is commonly administered as a part of multi-modal analgesia for cesarean delivery. Ketorolac pharmacokinetics is altered in pregnancy. The purpose of this study is to compare the efficacy of IV and intramuscular (IM) ketorolac for post-cesarean analgesia. Methodsː This study is a prospective, double blinded, randomized controlled trial to assess the efficacy of IV versus IM ketorolac administration on post-cesarean analgesia. Patients undergoing an elective cesarean delivery under spinal anesthesia were randomized to receive either 30 mg IV ketorolac (Group 30IV), 30 mg IM ketorolac (Group 30IM), or 60 mg IM ketorolac (Group 60IM). Primary outcomes include time to the first analgesic, total analgesic consumption, and pain scores. Secondary outcomes include patient satisfaction, opioid related side effects, and length of hospital stay. Resultsː The time to first break through pain was not statistically significant in the IM groups as compared to the IV group (Group 30IV 527 min, Group 30IM 578 min and Group 60IM 581 min). Pain scores and post-operative analgesic use did not differ significantly between groups. Secondary outcomes did not differ between groups. Conclusionsː IV and IM ketorolac are equally effective for post-cesarean analgesia.
背景剖宫产后最佳镇痛对促进产妇康复护理新生儿至关重要。静脉注射(IV)酮罗拉酸通常作为剖宫产多模式镇痛的一部分。酮咯酸药代动力学在妊娠期发生改变。本研究的目的是比较静脉注射和肌注酮罗拉酸对剖宫产后镇痛的效果。方法:本研究是一项前瞻性、双盲、随机对照试验,评估静脉注射与静脉注射酮罗拉酸对剖宫产后镇痛的疗效。在脊髓麻醉下择期剖宫产的患者被随机分为静脉注射30mg酮罗拉酸(30IV组)、静脉注射30mg酮罗拉酸(30IM组)或静脉注射60mg酮罗拉酸(60IM组)。主要结局包括首次使用镇痛药的时间、镇痛药总用量和疼痛评分。次要结局包括患者满意度、阿片类药物相关副作用和住院时间。结果IM组与静脉注射组(30IV组527 min、30IM组578 min、60IM组581 min)相比,首次突破疼痛时间无统计学意义。组间疼痛评分和术后镇痛药使用无显著差异。两组间的次要结果没有差异。结论静脉注射与静脉注射酮罗拉酸对剖宫产后镇痛效果相同。
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引用次数: 2
Preoperative Use of Continuous Positive Airway Pressure is related to Postoperative Respiratory Complications in Patients with Obstructive Sleep Apnea Undergoing Endoscopic Sinus Surgery 内镜鼻窦手术阻塞性睡眠呼吸暂停患者术前持续气道正压通气与术后呼吸并发症相关
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000871
A. Endo, Y. Kuwabara, K. Yamakawa, D. Sakamaki, A. Suzuki, I. Kondo, Y. Mio, S. Uezono
Backgrounds: Patients with obstructive sleep apnea (OSA) undergoing endoscopic sinus surgery (ESS) are considered at risk of postoperative respiratory complications because postoperative nasal packing often delays resumption of preoperative continuous positive airway pressure (CPAP) therapy. Our hospital implemented a policy in 2011 that all patients with OSA undergoing ESS be admitted to the intensive care unit (ICU) for at least 1 night for postoperative respiratory monitoring. We conducted the present study to evaluate the policy by examining the incidence of postoperative respiratory complications and to identify risk factors for postoperative respiratory complications in these patients. Methods: All patients with OSA scheduled for ESS from 2011 to 2015 were included in this retrospective chart review. Postoperative respiratory complication was defined as decrease of the percutaneous arterial oxygen saturation (SpO2) greater than 3% from each baseline or apnea for more than 20 seconds. We examined the incidence of respiratory complications and conducted multiple logistic regression analysis to determine risk factors for those of complications. Results: A total of 152 patients were analyzed. Postoperative respiratory complications were observed in 27 patients (17.8%) and the minimum value of SpO2 was 84%. None of these patients experienced severe sequelae. Multiple logistic regression analysis showed that preoperative CPAP use was an independent risk factor for postoperative respiratory complications (odds ratio=4.1; 95% CI=1.1–14.7). Conclusion: This retrospective study revealed a relatively high incidence of postoperative respiratory complications after ESS in patients with OSA. Our hospital policy of continuous respiratory monitoring in the ICU for at least 1 night postoperatively appears to be valid for these patients.
背景:阻塞性睡眠呼吸暂停(OSA)患者接受内窥镜鼻窦手术(ESS)被认为有术后呼吸并发症的风险,因为术后鼻腔填塞经常延迟术前持续气道正压(CPAP)治疗的恢复。我院于2011年实施了一项政策,即所有接受ESS治疗的OSA患者均需在重症监护病房(ICU)进行至少1晚的术后呼吸监测。我们进行了本研究,通过检查术后呼吸系统并发症的发生率来评估该政策,并确定这些患者术后呼吸系统并发症的危险因素。方法:回顾性分析2011 - 2015年所有计划进行ESS的OSA患者。术后呼吸并发症定义为经皮动脉血氧饱和度(SpO2)比每次基线下降大于3%或呼吸暂停超过20秒。我们检查了呼吸系统并发症的发生率,并进行了多元logistic回归分析,以确定并发症的危险因素。结果:共分析152例患者。术后出现呼吸系统并发症27例(17.8%),SpO2最小值为84%。这些患者均未出现严重的后遗症。多元logistic回归分析显示术前使用CPAP是术后呼吸系统并发症的独立危险因素(优势比=4.1;95% CI = 1.1 - -14.7)。结论:本回顾性研究显示OSA患者ESS术后呼吸系统并发症发生率较高。我院术后在ICU持续呼吸监测至少1晚的政策似乎对这些患者有效。
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引用次数: 0
Anesthetic Challenges in a Child with Pulmonary Agenesis: A Case Report and Review of Literature 小儿肺发育不全的麻醉挑战:1例报告及文献复习
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000833
M. Amin, D. Chin, Sima D. Amin, Anuradha Patel
Pulmonary agenesis is a rare congenital anomaly, which results in a complete absence in the development of lung tissue, bronchi, and pulmonary vessels. Pulmonary agenesis can occur on its own or it can often be found in conjunction with other congenital defects as part of VACTERL association. Anesthesia for patients with pulmonary agenesis can be challenging particularly when other defects or comorbidities exist. Here, we describe the successful anesthetic and ventilation management of a pediatric patient with right-sided unilateral pulmonary agenesis with VACTERL association.
肺发育不全是一种罕见的先天性异常,导致肺组织、支气管和肺血管发育完全缺失。肺发育不全可以单独发生,也可以经常与其他先天性缺陷一起发现,作为VACTERL关联的一部分。肺发育不全患者的麻醉具有挑战性,特别是当存在其他缺陷或合并症时。在这里,我们描述了成功的麻醉和通气管理的儿童患者右侧单侧肺发育不全与VACTERL关联。
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引用次数: 0
Paramedian Spinal Anesthesia: Landmark vs. Ultrasound-guided Approaches 辅助脊柱麻醉:地标与超声引导入路
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000837
Wirinaree Kampitak, T. Werawatganon, K. Uerpairojkit, B. Songthamwat
Background: Multiple attempts at needle redirection for paramedian spinal anesthesia can lead to significant complications, particularly in elderly patients. We hypothesized that ultrasound guidance may reduce the need for redirection (s), the associated discomfort, and complications in conventional landmark-guided paramedian spinal anesthesia. Methods: A total of 70 patients >65 years of age, undergoing total knee or hip arthroplasty, were randomly assigned to pre-procedural ultrasound-guided paramedian (PP) or conventional surface landmark-guided paramedian (CP) approach groups. The paramedian approach was performed at L3-4 in the lateral decubitus position. Results: The median number of needle redirection attempts was significantly lower in group PP (2 (interquartile range (IQR) 1-2)) than in group CP (4 (IQR 2-8.5)) (P<0.001). The median number of needle insertion attempts was also significantly lower in group PP than in group CP (P=0.003). All patients in group PP underwent successful needle insertion at the 3-4 lumbar intrathecal space, while 7 in group CP required multiple interspinous space insertions for success (P=0.006). No patient in group PP experienced significant complications related to spinal anesthesia. However, 5 (13.9%), 1 (2.8%), and 7 patients (19.4%) in group CP experienced transient radicular pain, paresthesia, and traumatic puncture, respectively. Conclusion: Application of pre-procedural ultrasound guidance in paramedian spinal anesthesia in elderly patients resulted in a significant decrease in the number of needle redirection and insertion attempts, as well as a reduction in related complications compared with the conventional paramedian technique.
背景:多次尝试在辅助脊髓麻醉针重定向可导致严重的并发症,特别是在老年患者。我们假设超声引导可以减少常规地标引导的辅助脊柱麻醉的重定向需求、相关不适和并发症。方法:70例年龄>65岁,行全膝关节或髋关节置换术的患者,随机分为术前超声引导下的辅助手术组(PP)和常规表面地标引导下的辅助手术组(CP)。在L3-4侧卧位行旁位入路。结果:PP组(2(四分位间距(IQR) 1 ~ 2))的中位数针头重定向次数明显低于CP组(4 (IQR 2 ~ 8.5)) (P<0.001)。PP组的中位插针次数明显低于CP组(P=0.003)。PP组所有患者均成功在3-4腰椎鞘内间隙插入针,而CP组7例患者需要多次棘间间隙插入针才成功(P=0.006)。PP组患者未出现明显的脊髓麻醉相关并发症。然而,CP组分别有5例(13.9%)、1例(2.8%)和7例(19.4%)患者出现短暂性神经根痛、感觉异常和外伤性穿刺。结论:术前超声引导在老年患者腰麻辅助手术中应用,与传统的腰麻辅助手术相比,可显著减少重针次数和插针次数,减少相关并发症。
{"title":"Paramedian Spinal Anesthesia: Landmark vs. Ultrasound-guided Approaches","authors":"Wirinaree Kampitak, T. Werawatganon, K. Uerpairojkit, B. Songthamwat","doi":"10.4172/2155-6148.1000837","DOIUrl":"https://doi.org/10.4172/2155-6148.1000837","url":null,"abstract":"Background: Multiple attempts at needle redirection for paramedian spinal anesthesia can lead to significant complications, particularly in elderly patients. We hypothesized that ultrasound guidance may reduce the need for redirection (s), the associated discomfort, and complications in conventional landmark-guided paramedian spinal anesthesia. Methods: A total of 70 patients >65 years of age, undergoing total knee or hip arthroplasty, were randomly assigned to pre-procedural ultrasound-guided paramedian (PP) or conventional surface landmark-guided paramedian (CP) approach groups. The paramedian approach was performed at L3-4 in the lateral decubitus position. Results: The median number of needle redirection attempts was significantly lower in group PP (2 (interquartile range (IQR) 1-2)) than in group CP (4 (IQR 2-8.5)) (P<0.001). The median number of needle insertion attempts was also significantly lower in group PP than in group CP (P=0.003). All patients in group PP underwent successful needle insertion at the 3-4 lumbar intrathecal space, while 7 in group CP required multiple interspinous space insertions for success (P=0.006). No patient in group PP experienced significant complications related to spinal anesthesia. However, 5 (13.9%), 1 (2.8%), and 7 patients (19.4%) in group CP experienced transient radicular pain, paresthesia, and traumatic puncture, respectively. Conclusion: Application of pre-procedural ultrasound guidance in paramedian spinal anesthesia in elderly patients resulted in a significant decrease in the number of needle redirection and insertion attempts, as well as a reduction in related complications compared with the conventional paramedian technique.","PeriodicalId":15000,"journal":{"name":"Journal of Anesthesia and Clinical Research","volume":"9 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86422209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Awake Cranioplasty: A Case Series 清醒颅骨成形术:一个病例系列
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000830
Halim Syahril, S. Gaus, Syafri K. Arif, Nur Surya Wirawan
Background: Cranioplasty restores the normal cranial architecture and protective functions of the skull and may play a role in normalizing cerebrospinal fluid dynamics in patients undergoing large craniectomies. It has a definitive impact on restoration of normal intracranial physiology and improvement of patient neurological condition. Anesthesia for awake neurosurgery procedure poses a unique challenge to anesthesiologists. Objective: To present cases of awake cranioplasty and describe the principles of anesthetic management during this procedure. Case description: 3 patients who have skull defect underwent cranioplasty procedure. Patients were managed with dexmedetomidine load of 1 mcg/kg over 10-15 min followed by infusion at rates of 0.2 mcg/kg/hr to 0.7 mcg/kg/hr and a local infiltration without airway instrumentation. Discussion: Awake cranioplasty offers great advantages with respect to patient outcome. In this type of procedure, the anesthesiologist’s goal is to make the operation safe and effective and reduce the psychophysical distress of the patient. Personal experience, careful planning, and attention to detail are the basis for obtaining good awake cranioplasty results. Dexmedetomidine is a highly specific α2 adrenoceptor agonist with sedative, analgesic, anesthetic sparing effect, awake if neither stimulated brain protection with no addiction effect nor suppress ventilation. Patients treated with dexmedetomidine will be sedated, comfortably but is easily aroused. Conclusion: Awake cranioplasty procedures were successfully performed with stable hemodynamic intraoperative and no complications during procedure. Dexmedetomidine has been shown to provide sedation and analgesia without significant respiratory depression and has been used successfully in these settings.
背景:颅骨成形术恢复了正常的颅骨结构和颅骨的保护功能,并可能在大颅骨切除术患者的脑脊液动力学正常化中发挥作用。它对恢复正常颅内生理和改善患者神经系统状况有明确的影响。清醒神经外科手术的麻醉对麻醉医师来说是一个独特的挑战。目的:介绍清醒颅骨成形术的病例,并阐述手术过程中的麻醉处理原则。病例描述:3例颅骨缺损患者行颅骨成形术。患者使用右美托咪定负荷为1微克/千克,持续10-15分钟,然后以0.2微克/千克/小时至0.7微克/千克/小时的速度输注,并在没有气道仪器的情况下进行局部浸润。讨论:清醒颅骨成形术在患者预后方面有很大的优势。在这种类型的手术中,麻醉师的目标是使手术安全有效,减少患者的心理和生理痛苦。个人经验,周密的计划和对细节的关注是获得良好的清醒颅骨成形术结果的基础。右美托咪定是一种高度特异的α - 2肾上腺素能受体激动剂,具有镇静、镇痛、省麻作用,清醒时既不刺激脑保护,又无成瘾性作用,也不抑制通气。用右美托咪定治疗的患者镇静舒适,但易被唤醒。结论:清醒颅骨成形术成功,术中血流动力学稳定,术中无并发症。右美托咪定已被证明可以提供镇静和镇痛而没有明显的呼吸抑制,并已成功地用于这些环境。
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引用次数: 1
Renal Autotransplantation and its Anesthetic Management: A Case Series in a Tertiary Hospital 自体肾移植及其麻醉管理:三甲医院病例分析
Pub Date : 2018-01-01 DOI: 10.4172/2155-6148.1000857
C. Mateus, Marta Araujo, C. Mexêdo, H. Machado
Introduction: Renal autotransplantation (RAT) is an unusual but safe procedure that implies a combination of living nephrectomy and a standard renal transplantation in the same patient. Indications for surgery include treatment of vascular and urologic lesions, and less frequently nephrolithiasis or chronic flank pain. Objectives: Due to rarity of the procedure there are a few reports published and little is known about anesthetic management of these patients. The goal of this study is to describe all cases of renal autotransplantation, focusing on anesthetic management. Methods: A retrospective review of the records of all patients who underwent renal auto transplantation from 2002 to 2015 in Centro Hospitalar do Porto was performed. Demographic, anesthetic, surgical and postoperative data were collected. Results: A total of twenty-four patients underwent renal autotransplantation from 2002 to 2015, including two patients who underwent bilateral RAT. The most frequent indication for RAT was the presence of renal artery aneurysms and most patients underwent laparoscopic nephrectomy. High-grade complications according to ClavienDindo classification occurred in 16% of patients. Hypertension was the most frequent comorbidity among patients. Combined anesthetic techniques were used in 52% of cases. Median duration of anesthesia was 423 min. There were no anesthetic complications, apart from one patient with hypothermia at the end of the procedure. Conclusions: RAT is a reasonable option for selected patients. Others studies are needed in order to provide evidence if anesthetic management influences outcomes.
自体肾移植(RAT)是一种不寻常但安全的手术,意味着在同一患者中,活体肾切除术和标准肾移植相结合。手术适应症包括治疗血管和泌尿系统病变,以及少见的肾结石或慢性侧腹疼痛。目的:由于手术的罕见性,发表的报道很少,对这些患者的麻醉管理知之甚少。本研究的目的是描述所有的肾脏自体移植病例,重点是麻醉管理。方法:回顾性分析2002 - 2015年波尔图中心医院所有自体肾移植患者的资料。收集人口统计学、麻醉、手术和术后数据。结果:2002 - 2015年共24例患者行自体肾移植,其中2例患者行双侧RAT。RAT最常见的适应症是存在肾动脉动脉瘤,大多数患者接受腹腔镜肾切除术。根据ClavienDindo分类,16%的患者出现了高级并发症。高血压是患者中最常见的合并症。52%的病例采用联合麻醉技术。麻醉中位持续时间为423分钟。除一名患者在手术结束时出现体温过低外,无麻醉并发症。结论:对于选定的患者,RAT是一个合理的选择。为了提供麻醉管理是否影响结果的证据,还需要其他研究。
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引用次数: 2
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Journal of Anesthesia and Clinical Research
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