Pub Date : 2023-08-04DOI: 10.4103/jcas.jcas_183_21
F. Kaliyadan, Jayasree Puravoor, K. Ashique
{"title":"Improving effectiveness of topical treatment in patients with vitiligo in lighter skin types by marking out skin lesions using ultraviolet lamps","authors":"F. Kaliyadan, Jayasree Puravoor, K. Ashique","doi":"10.4103/jcas.jcas_183_21","DOIUrl":"https://doi.org/10.4103/jcas.jcas_183_21","url":null,"abstract":"","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49285886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-04DOI: 10.4103/jcas.jcas_201_22
C. Asher, Daniel Oluboyede, Avelina I. Mario, C. Malata
Forehead defects pose a reconstructive challenge and multiple revisions are often required to achieve satisfactory outcomes. The case history of a 20-year-old woman undergoing radical resection of a forehead arteriovenous malformation and reconstruction with an anterolateral (ALT) free flap is described. Although free tissue transfer with an ALT was successful, its color and texture mismatch were unacceptable to the patient. The esthetic result and patient satisfaction were improved by subsequent tissue expansion of the contralateral forehead, removal of the free flap and advancement of the contralateral forehead skin. Complex reconstructions utilize a breadth of techniques. We illustrate a dynamic use of the reconstructive ladder, implementing a descending approach to achieve a satisfactory reconstruction objectively and subjectively from the patient perspective.
{"title":"Descending the reconstructive ladder: Salvage reconstruction by tissue expansion to revise a free flap-based forehead reconstruction","authors":"C. Asher, Daniel Oluboyede, Avelina I. Mario, C. Malata","doi":"10.4103/jcas.jcas_201_22","DOIUrl":"https://doi.org/10.4103/jcas.jcas_201_22","url":null,"abstract":"\u0000 \u0000 \u0000 Forehead defects pose a reconstructive challenge and multiple revisions are often required to achieve satisfactory outcomes.\u0000 \u0000 \u0000 \u0000 The case history of a 20-year-old woman undergoing radical resection of a forehead arteriovenous malformation and reconstruction with an anterolateral (ALT) free flap is described.\u0000 \u0000 \u0000 \u0000 Although free tissue transfer with an ALT was successful, its color and texture mismatch were unacceptable to the patient. The esthetic result and patient satisfaction were improved by subsequent tissue expansion of the contralateral forehead, removal of the free flap and advancement of the contralateral forehead skin.\u0000 \u0000 \u0000 \u0000 Complex reconstructions utilize a breadth of techniques. We illustrate a dynamic use of the reconstructive ladder, implementing a descending approach to achieve a satisfactory reconstruction objectively and subjectively from the patient perspective.\u0000","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49110859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post-acne atrophic scars (PAS) are a common complication of acne, and their treatment can be limited in people of color due to dyspigmentation and scarring risks. This split-face study compared the efficacy of microneedling with topical insulin (TI) on one side of the face with microneedling with platelet-rich plasma (PRP) on the other side for the treatment of PAS. The study included 50 participants with Fitzpatrick skin types III to VI who had never been treated for PAS. Both sides of the face showed significant improvement, with the left side (TI) showing a 52% improvement and the right side (PRP) showing a 28% improvement. The treatment was well-tolerated, with no significant adverse effects, and no changes in blood glucose levels were observed. The researchers suggest that combining TI or PRP with microneedling can improve PAS treatment, with TI being a superior option due to its ease of use, low cost, and noninvasive nature.
{"title":"Microneedling with autologous platelet-rich plasma versus topical insulin for treating postacne scars: A split-face comparison","authors":"A. Mohta, M. Yadav, B. Ghiya","doi":"10.4103/jcas.jcas_20_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_20_23","url":null,"abstract":"\u0000 Post-acne atrophic scars (PAS) are a common complication of acne, and their treatment can be limited in people of color due to dyspigmentation and scarring risks. This split-face study compared the efficacy of microneedling with topical insulin (TI) on one side of the face with microneedling with platelet-rich plasma (PRP) on the other side for the treatment of PAS. The study included 50 participants with Fitzpatrick skin types III to VI who had never been treated for PAS. Both sides of the face showed significant improvement, with the left side (TI) showing a 52% improvement and the right side (PRP) showing a 28% improvement. The treatment was well-tolerated, with no significant adverse effects, and no changes in blood glucose levels were observed. The researchers suggest that combining TI or PRP with microneedling can improve PAS treatment, with TI being a superior option due to its ease of use, low cost, and noninvasive nature.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46157631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kavita Bisherwal, A. Singal, Anil Bhoi, Sonal Sharma
Cutaneous horn, characterized by conical protrusion arising from the skin surface, comprises of hyperkeratotic epidermis. It is commonly seen on photo-exposed body parts in elderly men and can arise from benign, premalignant, or malignant dermatoses. There are scarce reports of cutaneous horn developing in association with discoid lupus erythematosus (DLE). We report an interesting case of cutaneous horn with underlying well-differentiated squamous cell carcinoma arising over chronic scarred lesion of DLE on the scalp.
{"title":"Cutaneous horn with underlying squamous cell carcinoma complicating discoid lupus erythematosus of scalp: A hitherto unreported complication","authors":"Kavita Bisherwal, A. Singal, Anil Bhoi, Sonal Sharma","doi":"10.4103/jcas.jcas_61_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_61_23","url":null,"abstract":"\u0000 Cutaneous horn, characterized by conical protrusion arising from the skin surface, comprises of hyperkeratotic epidermis. It is commonly seen on photo-exposed body parts in elderly men and can arise from benign, premalignant, or malignant dermatoses. There are scarce reports of cutaneous horn developing in association with discoid lupus erythematosus (DLE). We report an interesting case of cutaneous horn with underlying well-differentiated squamous cell carcinoma arising over chronic scarred lesion of DLE on the scalp.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44255376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neha Pralhad Deokar, B. Nikam, A. Hussain, Varsha Jamale
Lymphangioma circumscriptum is a “microcytic” lymphatic malformation. Different treatments have been tried with varying success. We report here a case of recurrent lymphangioma circumscriptum who was treated with microneedling radiofrequency (MNRF) and topical preparation or sirolimus cream with good improvement. A 14-year-old girl presented to outpatient department with a cluster of small asymptomatic blisters over the unilateral inguinal area which on histopathology was confirmed to be lymphangioma circumscriptum. The patient had similar lesions 3 years back which she got surgically excised. Since the last 6 months, she had a recurrence of the similar lesions so this time we chose MNRF every 40 days to treat this case which was combined with topical sirolimus 0.01% during and after the procedure. MNRF helps in neoelastogenesis and neocollagenosis, which leads to dermal thickening. It also acts as a drug delivery system by creating dermal channels. Sirolimus with its antilymphangiogenic properties helps prevent recurrence.
{"title":"Recurrent lymphangioma circumscriptum: Treated with microneedling radiofrequency and topical sirolimus","authors":"Neha Pralhad Deokar, B. Nikam, A. Hussain, Varsha Jamale","doi":"10.4103/jcas.jcas_50_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_50_23","url":null,"abstract":"\u0000 \u0000 \u0000 Lymphangioma circumscriptum is a “microcytic” lymphatic malformation. Different treatments have been tried with varying success. We report here a case of recurrent lymphangioma circumscriptum who was treated with microneedling radiofrequency (MNRF) and topical preparation or sirolimus cream with good improvement.\u0000 \u0000 \u0000 \u0000 A 14-year-old girl presented to outpatient department with a cluster of small asymptomatic blisters over the unilateral inguinal area which on histopathology was confirmed to be lymphangioma circumscriptum. The patient had similar lesions 3 years back which she got surgically excised. Since the last 6 months, she had a recurrence of the similar lesions so this time we chose MNRF every 40 days to treat this case which was combined with topical sirolimus 0.01% during and after the procedure.\u0000 \u0000 \u0000 \u0000 MNRF helps in neoelastogenesis and neocollagenosis, which leads to dermal thickening. It also acts as a drug delivery system by creating dermal channels. Sirolimus with its antilymphangiogenic properties helps prevent recurrence.\u0000","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49179041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Preema Sinha, Mahashweta Dash, M. Madakshira, Juhi Sharma
{"title":"A case of granulomatous dermatitis following dermaroller therapy for acne scars treated with methotrexate: A difficult-to-treat condition","authors":"Preema Sinha, Mahashweta Dash, M. Madakshira, Juhi Sharma","doi":"10.4103/jcas.jcas_26_23","DOIUrl":"https://doi.org/10.4103/jcas.jcas_26_23","url":null,"abstract":"","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43268264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-04DOI: 10.4103/jcas.jcas_173_20
S. Puri, Akhilesh Shewale
Excessive gingival display can be managed by a variety of treatment modalities, depending on the specific diagnosis. Lip repositioning surgery is a largely unknown and underutilized treatment modality for excessive gingival display. The aim of the present study was to minimize gingival display by comparing the modified lip repositioning procedure with the conventional lip repositioning procedure. A total of 12 patients with gummy smile were selected for the study. The patients were randomly divided into two groups (group A and group B), consisting of six patients each. Group A patients were treated with conventional lip repositioning procedure and group B patients were treated with modified lip repositioning procedure. The procedure resulted in a narrower vestibule and restricted muscle pull, thereby reducing gingival display during smiling. The lip repositioning technique that was meant to decrease the amount of gingival display proved to be more conservative and provided good aesthetic outcome.
{"title":"Comparative evaluation of conventional versus modified lip repositioning surgery for gummy smile: A Two-year follow-up study","authors":"S. Puri, Akhilesh Shewale","doi":"10.4103/jcas.jcas_173_20","DOIUrl":"https://doi.org/10.4103/jcas.jcas_173_20","url":null,"abstract":"\u0000 \u0000 \u0000 Excessive gingival display can be managed by a variety of treatment modalities, depending on the specific diagnosis. Lip repositioning surgery is a largely unknown and underutilized treatment modality for excessive gingival display. The aim of the present study was to minimize gingival display by comparing the modified lip repositioning procedure with the conventional lip repositioning procedure.\u0000 \u0000 \u0000 \u0000 A total of 12 patients with gummy smile were selected for the study. The patients were randomly divided into two groups (group A and group B), consisting of six patients each. Group A patients were treated with conventional lip repositioning procedure and group B patients were treated with modified lip repositioning procedure.\u0000 \u0000 \u0000 \u0000 The procedure resulted in a narrower vestibule and restricted muscle pull, thereby reducing gingival display during smiling.\u0000 \u0000 \u0000 \u0000 The lip repositioning technique that was meant to decrease the amount of gingival display proved to be more conservative and provided good aesthetic outcome.\u0000","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47710381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alistair Campbell Brown, Toby Nelson, Sarah C Nelson
The paramedian forehead flap (PFF) provides a reliable reconstruction option for complex nasal tip defects. The robust blood supply from a well perfused pedicle allows for reconstruction of large defects of the nasal tip for which simpler methods/techniques would provide inadequate coverage or result in inferior cosmesis. A well-designed PFF containing the supratrochlear artery inherently predisposes to small vessel bleeding from the pedicles cut edge. Due to the well perfused nature of the pedicle, there is an increased risk of post-operative bleeding. We describe a technique for better identifying bleeding points from the pedicle to optimise intra-operative haemostasis by performing the Valsalva maneuver using a syringe intraoperatively.
{"title":"Valsalva maneuver to identify dermal bleeders after paramedian flap elevation under local anesthesia","authors":"Alistair Campbell Brown, Toby Nelson, Sarah C Nelson","doi":"10.4103/jcas.jcas_98_22","DOIUrl":"https://doi.org/10.4103/jcas.jcas_98_22","url":null,"abstract":"The paramedian forehead flap (PFF) provides a reliable reconstruction option for complex nasal tip defects. The robust blood supply from a well perfused pedicle allows for reconstruction of large defects of the nasal tip for which simpler methods/techniques would provide inadequate coverage or result in inferior cosmesis. A well-designed PFF containing the supratrochlear artery inherently predisposes to small vessel bleeding from the pedicles cut edge. Due to the well perfused nature of the pedicle, there is an increased risk of post-operative bleeding. We describe a technique for better identifying bleeding points from the pedicle to optimise intra-operative haemostasis by performing the Valsalva maneuver using a syringe intraoperatively.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139364808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jcas.jcas_206_22
Michael A Kaiser, Lina M Ferrari, Simonetta I Gaumond, Najy Issa, Joaquin J Jimenez, N. Issa
Androgenetic alopecia (AGA) is the most common cause of alopecia in males and females. Minoxidil and finasteride are the only FDA-approved treatments for AGA. New treatments including Platelet Rich Plasma (PRP) and microneedling have shown promising results. The purpose of this literature review was to highlight recent studies examining the effects of topical minoxidil combined with PRP to minoxidil or PRP monotherapy. The method used for this paper includes a systematic review of the literature from 2010 to 2022 using the PubMed, EMBASE, and MEDLINE databases examining studies evaluating combination therapies for AGA. Three randomized control trials compared combination PRP + topical 5% minoxidil to either no treatment, 5% minoxidil, or PRP only. Two studies found increased hair growth at five months and at six months following combined therapy. Another study found an increase in hair density and improved patient satisfaction with combination therapy compared to monotherapy. A prospective study revealed that patients treated with combined 5% minoxidil, PRP, and microneedling reported the highest patient and physician satisfaction compared to minoxidil monotherapy. An observational study evaluating topical 5% minoxidil with PRP reported an increase in hair diameter after one year of combination treatment compared to minoxidil monotherapy. PRP therapy combined with minoxidil and microneedling in a retrospective study was shown to increase hair growth compared to PRP with minoxidil as well as PRP or minoxidil monotherapy. In conclusion, a variety of studies demonstrated superior treatment response with a combination of PRP and minoxidil therapy in patients with AGA. Limitations to this study include different PRP preparation protocols, few randomized control studies, and small sample sizes.
{"title":"Platelet rich plasma combination therapies for treatment of androgenetic alopecia: A systematic review","authors":"Michael A Kaiser, Lina M Ferrari, Simonetta I Gaumond, Najy Issa, Joaquin J Jimenez, N. Issa","doi":"10.4103/jcas.jcas_206_22","DOIUrl":"https://doi.org/10.4103/jcas.jcas_206_22","url":null,"abstract":"Androgenetic alopecia (AGA) is the most common cause of alopecia in males and females. Minoxidil and finasteride are the only FDA-approved treatments for AGA. New treatments including Platelet Rich Plasma (PRP) and microneedling have shown promising results. The purpose of this literature review was to highlight recent studies examining the effects of topical minoxidil combined with PRP to minoxidil or PRP monotherapy. The method used for this paper includes a systematic review of the literature from 2010 to 2022 using the PubMed, EMBASE, and MEDLINE databases examining studies evaluating combination therapies for AGA. Three randomized control trials compared combination PRP + topical 5% minoxidil to either no treatment, 5% minoxidil, or PRP only. Two studies found increased hair growth at five months and at six months following combined therapy. Another study found an increase in hair density and improved patient satisfaction with combination therapy compared to monotherapy. A prospective study revealed that patients treated with combined 5% minoxidil, PRP, and microneedling reported the highest patient and physician satisfaction compared to minoxidil monotherapy. An observational study evaluating topical 5% minoxidil with PRP reported an increase in hair diameter after one year of combination treatment compared to minoxidil monotherapy. PRP therapy combined with minoxidil and microneedling in a retrospective study was shown to increase hair growth compared to PRP with minoxidil as well as PRP or minoxidil monotherapy. In conclusion, a variety of studies demonstrated superior treatment response with a combination of PRP and minoxidil therapy in patients with AGA. Limitations to this study include different PRP preparation protocols, few randomized control studies, and small sample sizes.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Madegowda, H. Rajegowda, Deepadarshan Kalegowda, Phani Halevoor Nagaraju, Hemalatha Mullagura Naidu
Striae distensae are atrophic scars that are often cosmetically distressing. The efficacy of fractional carbon dioxide (CO2) laser and platelet-rich plasma (PRP) in treating striae individually has been evaluated previously. However, not many studies described the combined efficacy of both. The aim of this study was to compare the efficacy and safety of fractional CO2 laser alone and in combination with PRP. Twenty-four patients with striae presenting bilaterally in the abdomen, upper limbs, and lower limbs were included. PRP was prepared by double-spin method and cell count was done to ensure at least fourfold concentration of platelets. The patients were treated CO2 laser on both sides and PRP on the left side along with laser, every month for three sessions. Digital photography and dermoscopy were done at baseline, every treatment session, and 6 months after treatment. Clinical improvement was assessed by comparing photographs and patient satisfaction before and after treatment. All patients showed improvement on both sides. In CO2-laser-treated patients, responses in 6 patients (25%) were moderate, 14 (56%) were good, and 4 (16.6%) were excellent. In CO2-laser and PRP-treated patients, responses in 5 patients (20.8%) were moderate, 11 (45.8%) were good, and 8 (33.3%) were excellent. Hyperpigmentation was the most common side-effect seen (19 patients) on both sides, which resolved spontaneously by 6 months. These results support the use of ablative CO2 fractional laser as effective and safe treatment modalities for striae. However, slightly better efficacy was noted with the addition of PRP.
{"title":"Efficacy of fractional carbon dioxide laser versus fractional carbon dioxide laser with platelet-rich plasma in treatment of striae distensae in a tertiary care center: A comparative study","authors":"S. Madegowda, H. Rajegowda, Deepadarshan Kalegowda, Phani Halevoor Nagaraju, Hemalatha Mullagura Naidu","doi":"10.4103/jcas.jcas_65_22","DOIUrl":"https://doi.org/10.4103/jcas.jcas_65_22","url":null,"abstract":"Striae distensae are atrophic scars that are often cosmetically distressing. The efficacy of fractional carbon dioxide (CO2) laser and platelet-rich plasma (PRP) in treating striae individually has been evaluated previously. However, not many studies described the combined efficacy of both. The aim of this study was to compare the efficacy and safety of fractional CO2 laser alone and in combination with PRP. Twenty-four patients with striae presenting bilaterally in the abdomen, upper limbs, and lower limbs were included. PRP was prepared by double-spin method and cell count was done to ensure at least fourfold concentration of platelets. The patients were treated CO2 laser on both sides and PRP on the left side along with laser, every month for three sessions. Digital photography and dermoscopy were done at baseline, every treatment session, and 6 months after treatment. Clinical improvement was assessed by comparing photographs and patient satisfaction before and after treatment. All patients showed improvement on both sides. In CO2-laser-treated patients, responses in 6 patients (25%) were moderate, 14 (56%) were good, and 4 (16.6%) were excellent. In CO2-laser and PRP-treated patients, responses in 5 patients (20.8%) were moderate, 11 (45.8%) were good, and 8 (33.3%) were excellent. Hyperpigmentation was the most common side-effect seen (19 patients) on both sides, which resolved spontaneously by 6 months. These results support the use of ablative CO2 fractional laser as effective and safe treatment modalities for striae. However, slightly better efficacy was noted with the addition of PRP.","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139365944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：