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Modified platelet rich plasma therapy for alopecia totalis. 改良型富血小板血浆疗法治疗全秃。
Q3 Medicine Pub Date : 2024-04-01 DOI: 10.4103/JCAS.JCAS_101_22
Avita Dhiman, Manmohan Bagri

Alopecia areata (AA) is an autoimmune disease characterized most commonly by patchy nonscarring hair loss which may progress to alopecia totalis which has poor prognosis. Platelet-rich plasma (PRP) therapy along with intralesional triamcinolone acetonide that is modified PRP proved to be beneficial in the case of alopecia totalis and helps in weaning patient off oral immunosuppression.

斑秃(AA)是一种自身免疫性疾病,最常见的特征是斑片状非瘢痕性脱发,可发展为预后不良的全秃。事实证明,富血小板血浆(PRP)疗法以及经改良的PRP内服曲安奈德(triamcinolone acetonide)对全脱发患者有益,有助于患者摆脱口服免疫抑制剂。
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引用次数: 0
Translation and validation of Hindi version of patient scar assessment scale in patients with postburn facial scar 翻译并验证印地语版烧伤后面部疤痕患者疤痕评估量表
Q3 Medicine Pub Date : 2024-02-16 DOI: 10.4103/jcas.jcas_11_22
Arkapal Bandopadhyay, Akshay Kapoor, Kaustav Kundu, Manish Jagtap, D. Chattopadhyay
Patient scar assessment scale (PSAS) is a reliable and standard tool for assessment of scars by the observer and the patient. Till now the scale has not been translated to Hindi. The objective of the study was to translate and validate the PSAS to Hindi. We did forward and backward translation of the English PSAS together with its validation. In total, 64 patients with postburn facial scars were included. The validation committee consisted of 6 bilingual members. The PSAS-Hindi showed good internal consistency with Cronbach’s α of 0.86. Test–retest reliability showed good correlation with intra class coefficient being 0.94 (95% confidence interval: 0.83–0.97). The PSAS was successfully translated to Hindi, and cross-cultural adaptation was made.
患者疤痕评估量表(PSAS)是观察者和患者评估疤痕的可靠标准工具。迄今为止,该量表尚未翻译成印地语。本研究的目的是将 PSAS 翻译成印地语并进行验证。 我们对英语 PSAS 进行了正向和反向翻译,并对其进行了验证。共纳入了 64 名面部烧伤后疤痕患者。验证委员会由 6 名双语成员组成。 印地语 PSAS 显示出良好的内部一致性,Cronbach's α 为 0.86。测试-再测可靠性显示出良好的相关性,类内系数为 0.94(95% 置信区间:0.83-0.97)。 PSAS 已成功翻译成印地语,并进行了跨文化调整。
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引用次数: 0
Scalp rupture-related acute hair matting in a child: A case letter 一名儿童因头皮破裂导致急性毛发枯黄:一封病例信
Q3 Medicine Pub Date : 2024-02-05 DOI: 10.4103/jcas.jcas_139_22
Bahareh Abtahi-Naeini, Fereshte Rastegarnasab, Mahsa Pourmahdi-Boroujeni
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引用次数: 0
Scalp rupture-related acute hair matting in a child: A case letter 一名儿童因头皮破裂导致急性毛发枯黄:一封病例信
Q3 Medicine Pub Date : 2024-02-05 DOI: 10.4103/jcas.jcas_139_22
Bahareh Abtahi-Naeini, Fereshte Rastegarnasab, Mahsa Pourmahdi-Boroujeni
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引用次数: 0
Efficacy of platelet-rich plasma in alleviating split skin graft morbidities. 富含血小板的血浆在缓解分瓣植皮病症方面的功效。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.4103/JCAS.JCAS_14_21
Veda Samhitha Chigurupati, Seema Khanna, Sandip Kumar, Rahul Khanna

Introduction: Skin grafting is a routinely employed technique to cover the skin defect. Though the skin grafts are technically effortless, they are tiresome because of the prolonged duration of hospital stay, labor-intensive, demanding repeated dressings, and also create a second wound. Platelet-rich plasma (PRP) is one that has a higher concentration of platelets than the blood. Alpha granules of the platelets are rich in growth factors.

Aims and objectives: To assess the effect of PRP on split-thickness skin graft uptake and donor site healing.

Materials and methods: In a single-center-based prospective study done from August 2018 to June 2020, 60 patients with acute and chronic wounds were divided into two equal groups. Autologous PRP was applied on the recipient wound bed and donor site in PRP group, and conventional methods like staples/sutures were used to anchor the skin grafts and standard of care of the donor site in a control group.

Results: Instantaneous graft adhesion was observed in all patients of PRP group. The first graft inspection was delayed. Seroma, hematoma, total number of dressings, and duration of stay in hospital were significantly reduced in the PRP group. Donor site pain in the postoperative period was notably reduced in PRP group. PRP also remarkably hastened the donor site healing.

Conclusion: The application of PRP promotes graft take, minimizes complications, enhances donor site wound healing, mitigates donor site pain, and has immense economic benefits due to the reduced number of dressing changes and shorter hospital stay.

介绍:植皮是一种常规的皮肤缺损覆盖技术。虽然植皮在技术上不费吹灰之力,但由于住院时间长、劳动强度大、需要反复包扎,而且还会造成第二个伤口,因此令人厌倦。富血小板血浆(PRP)是一种血小板浓度高于血液的血浆。血小板的α颗粒富含生长因子:评估 PRP 对分层厚皮移植吸收和供体部位愈合的影响:在2018年8月至2020年6月进行的一项基于单中心的前瞻性研究中,60名急性和慢性伤口患者被分为两组。PRP组在受体伤口床和供体部位涂抹自体PRP,对照组使用订书机/缝合线等传统方法固定植皮,并对供体部位进行标准护理:结果:PRP 组的所有患者均观察到移植物瞬间粘连。结果:PRP 组所有患者均观察到移植物瞬间粘连,而首次移植物检查则出现延迟。PRP 组的血清肿、血肿、敷料总数和住院时间明显缩短。PRP 组术后供体部位疼痛明显减轻。PRP还明显加快了供体部位的愈合:结论:应用 PRP 可促进移植物吸收、减少并发症、促进供体部位伤口愈合、减轻供体部位疼痛,并且由于减少了换药次数和缩短了住院时间,因此具有巨大的经济效益。
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引用次数: 0
Treatment of Fordyce Spots with CO2 Laser: A Case Series of Three Patients. CO2激光治疗福代斯斑:附3例
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.4103/JCAS.JCAS_159_22
Yogesh M Bhingradia, Abhishek Shriram Patokar, Nilam Moradiya

The Fordyce spots are ectopic sebaceous glands, located at the lip's vermilion border or the oral mucosa. Clinically presents as tiny, discrete, white or yellowish, focally grouped papules. It is a common cosmetic disorder and is significantly associated with emotional stress. Herein, we describe three cases that showed satisfactory cosmetic results after the treatment of Fordyce spots using a CO2 laser. Patients were 21-year-old, 25-year-old, and 28-year-old males with Fordyce spots on the upper lip. They were treated with the CO2 laser and after 4 months of treatment, no recurrence was noted. Treatment with pinhole ablation with CO2 laser improves cosmetic results, reduces downtime, and minimizes side effects. To the best of our knowledge, no such case series have been reported to date from the Indian subcontinent.

福特斯斑是一种异位皮脂腺,位于嘴唇的朱砂边缘或口腔粘膜。临床表现为微小、离散、白色或淡黄色、局部成群的丘疹。这是一种常见的美容疾病,与情绪压力有很大关系。在此,我们介绍了三例使用二氧化碳激光治疗福特斯斑后获得满意美容效果的病例。患者分别是 21 岁、25 岁和 28 岁的男性,上唇有福特斯斑。他们接受了二氧化碳激光治疗,治疗 4 个月后未发现复发。使用二氧化碳激光进行针孔消融治疗可改善美容效果,减少停工期,并将副作用降至最低。据我们所知,迄今为止,印度次大陆还没有此类系列病例的报道。
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引用次数: 0
A Clinical and Dermatoscopic Perspective of the Efficacy and Safety of Erbium: YAG Laser Ablation Versus 50% Trichloroacetic Acid for the Management of Xanthelasma Palpebrarum. 从临床和皮肤镜角度看铒钇钕石榴石(Erbium:YAG激光消融术与50%三氯乙酸治疗掌跖黄褐斑的临床效果与安全性对比。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.4103/JCAS.JCAS_157_22
Aakanksha Arora, Alpana Mohta, Rajesh Datt Mehta, Bhikam Chand Ghiya, Prasoon Soni, Vishnu Kumar Jangir, Manoj Kumar Yadav, Rajesh Khokhar, Vijay Mangava

Xanthelasma palpebrarum (XP) is a benign cosmetic condition. Although the role of CO2 laser is well described, there are only a few studies on Erbium: YAG in XP. Similarly, trichloroacetic acid (TCA) is commonly used in XP. However, there are only a few studies comparing these modalities in the treatment of XP.

Aim: To evaluate the effectiveness and safety of Erbium: YAG laser and 50% TCA in the treatment of XP with the role of dermoscope in the evaluation of lesions.

Materials and methods: A total of 20 subjects were randomly allocated into two groups: group A (TCA) and group B (laser). All patients were subcategorized into three grades viz. I (mild), II (moderate), and III (severe) using a self-devised scoring system.

Results: About 25% and 70% of patients achieved complete clearance in groups A and B, respectively (P = 0.017). The rate of recurrence was 40% and 15% in groups A and B. Dyspigmentation and erythema were the most common side effects. Pretreatment dermoscopic evaluation of the lesion showed a network of brown streaks on a background of a yellowish structureless area and was used to assess the area and margins of the lesion where the adipose tissue was found during the procedure and serial assessment of the lesion.

睑外翻(XP)是一种良性的美容疾病。虽然 CO2 激光的作用已被充分描述,但关于 Erbium:YAG激光治疗XP的研究很少。同样,三氯乙酸(TCA)也常用于 XP。目的:评估铒:YAG 激光和 50%三氯乙酸治疗 XP 的有效性和安全性:材料与方法:将 20 名受试者随机分为两组:A 组(TCA)和 B 组(激光)。采用自定的评分系统将所有患者分为三个等级,即 I 级(轻度)、II 级(中度)和 III 级(重度):结果:A 组和 B 组分别有约 25% 和 70% 的患者实现了完全清除(P = 0.017)。色素沉着和红斑是最常见的副作用。皮损治疗前的皮肤镜评估显示,在淡黄色无结构区域的背景上有棕色条纹网络,用于评估手术中发现脂肪组织的区域和皮损边缘,并对皮损进行连续评估。
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引用次数: 0
Micro-face-lift: A novel biplanar, composite, less-invasive procedure. 微面部提升:一种新型的双平面、复合、微创手术
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.4103/JCAS.JCAS_71_23
Yoram Wolf, Rami Selinger, Ron Skorochod, Vladimir Mitz

Background: Facial rejuvenation procedures have been in existence for over a century. Since its first introduction, it improved anatomical understanding and clinical implications and gave rise to numerous techniques and re-ideations of the original face-lift. The increase in popularity of face-lift procedures attracts patients of various ages and with different medical comorbidities. In this paper, we describe the less-invasive facelift procedure, termed the "Micro-Face-lift," with minimal complications, a short recovery period, and few contraindications.

Materials and methods: The authors retrospectively analyzed the medical files of 51 patients who underwent the "Micro-Face-lift" procedure between 2014 and 2019 by three independent surgeons.

Results: Fifty-one patients met the inclusion criteria for the procedure. Forty-nine patients were women (96.1%) and the remainder were men (3.9%). The mean age at the time of the procedure was 60.8 years (range 45-87). Complications were encountered in five patients (9.8%): two hypertrophic scars (3.8%), one hematoma (2%), one surgical wound infection (2%), and one edema (2%), persistent for more than 2 weeks postoperatively. All complications resolved within 6 weeks of postoperatively. Thirty-five patients (68.6%) underwent additional procedures to maximize the aesthetic outcome. Thirty patients (58.8%) underwent submental liposuction and five patients (9.8%) underwent mid-face lipo-filling. The average satisfaction score on the self-reported "Likert" scale was 4.27 (range 1-5). All patients were followed for a minimum period of 18 months.

Conclusions: The "Micro-Face-lift" is a less-invasive procedure that can be performed under local anesthesia and sedation in the outpatient setting. Complication rates and mortality are low, contraindications are rare, and the recovery period is short. In our experience, patient satisfaction is high with the Micro-Face-lift procedure, and the learning curve for the experienced practitioner is short.

面部再生程序已经存在了一个多世纪。自首次引入以来,它提高了对解剖学的理解和临床意义,并产生了许多原始面部提升的技术和重新构思。整容手术越来越受欢迎,吸引了不同年龄和不同医学合并症的患者。在这篇论文中,我们描述了一种微创的整容手术,称为“微型整容”,并发症最小,恢复期短,禁忌症少。作者回顾性分析了2014年至2019年间由三名独立外科医生进行“微型面部提升”手术的51名患者的医疗档案。51名患者符合该手术的入选标准。49名患者为女性(96.1%),其余为男性(3.9%)。手术时的平均年龄为60.8岁(45-87岁)。5名患者(9.8%)出现并发症:2个增生性瘢痕(3.8%)、1个血肿(2%)、1例手术伤口感染(2%)和1例水肿(2%),术后持续2周以上。所有并发症在术后6周内得到解决。35名患者(68.6%)接受了额外的手术,以最大限度地提高美观效果。30名患者(58.8%)接受了颏下吸脂术,5名患者(9.8%)接受了面部脂肪填充术。自我报告的“Likert”量表的平均满意度得分为4.27(范围1-5)。所有患者均接受了至少18个月的随访。“微整容”是一种微创手术,可以在门诊环境中在局部麻醉和镇静下进行。并发症发生率和死亡率低,禁忌症少,恢复期短。根据我们的经验,患者对微型面部提拉手术的满意度很高,而经验丰富的从业者的学习曲线很短。
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引用次数: 0
Patient Perspectives on Hidradenitis Suppurativa-induced Scarring and Laser Therapy. 化脓性汗腺炎致瘢痕形成和激光治疗的患者观点
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.4103/JCAS.JCAS_83_23
Michelle Toker, Eliza Balazic, Lesley Coe, McCall Torpey, Kristina L Campton, Kseniya Kobets
{"title":"Patient Perspectives on Hidradenitis Suppurativa-induced Scarring and Laser Therapy.","authors":"Michelle Toker, Eliza Balazic, Lesley Coe, McCall Torpey, Kristina L Campton, Kseniya Kobets","doi":"10.4103/JCAS.JCAS_83_23","DOIUrl":"10.4103/JCAS.JCAS_83_23","url":null,"abstract":"","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":" ","pages":"69-72"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11086928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48579988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of therapeutic efficacy and safety of black peel versus 25% trichloroacetic acid peel in mild to moderate acne vulgaris: a split face study. 黑果酸换肤与 25% 三氯醋酸换肤对轻中度寻常型痤疮疗效和安全性的比较评估:分脸研究。
Q3 Medicine Pub Date : 2024-01-01 DOI: 10.4103/JCAS.JCAS_69_23
Neerja Puri, Sumir Kumar, Sameer Kaur, B K Brar

Introduction: Peeling has withstood the test of time as a simple, minimally invasive method to renew the skin, despite the introduction of more advanced procedures like lasers.

Materials and methods: Thirty patients (or 60 sites) with age ranging from 15 to 45 years with mild-to-moderate acne vulgaris were included in the study. Assessment at baseline was done by the global acne grading system score for including mild and moderate acne patients.

Results: On grading the improvement according to the 5-point Global Assessment Scale (GAS), it was found that in area A (black peel), 6.7% of patients showed excellent improvement, 86.7% of patients showed good improvement, and 6.7% of patients showed fair improvement. In area B (25%TCA peel), 6.7% of patients showed excellent improvement, 80% of patients showed good improvement, and 13.3% of patients showed fair improvement.

Discussion: None of the patients showed poor or worse outcomes in any of the areas. The difference between the groups was not significant (P = 0.688).

Conclusion: There is a paucity of data in the literature regarding the comparison of black peel with other conventional peels in the treatment of acne vulgaris. To the best of our knowledge, this is the first study comparing black peel with TCA peel in the treatment of acne vulgaris.

简介:作为一种简单、微创的皮肤更新方法,去皮术经受住了时间的考验,尽管激光等更先进的治疗方法已经问世:研究对象包括 30 名年龄在 15 至 45 岁之间、患有轻度至中度寻常型痤疮的患者(或 60 个部位)。对轻度和中度痤疮患者的基线评估采用全球痤疮分级系统评分法:根据 5 分全球评估量表(GAS)对改善情况进行评分,发现在 A 区(黑色脱皮),6.7% 的患者改善情况极佳,86.7% 的患者改善情况良好,6.7% 的患者改善情况一般。在 B 区(25%TCA 去皮),6.7% 的患者有极好的改善,80% 的患者有良好的改善,13.3% 的患者有一般的改善:讨论:没有患者在任何一个部位的治疗效果不佳或较差。讨论:没有一名患者在任何方面的疗效不佳或较差,组间差异不显著(P = 0.688):关于黑果皮与其他传统换肤疗法在治疗寻常型痤疮方面的比较,文献中的数据很少。据我们所知,这是第一项在治疗寻常型痤疮时比较黑果皮与 TCA 果皮的研究。
{"title":"Comparative evaluation of therapeutic efficacy and safety of black peel versus 25% trichloroacetic acid peel in mild to moderate acne vulgaris: a split face study.","authors":"Neerja Puri, Sumir Kumar, Sameer Kaur, B K Brar","doi":"10.4103/JCAS.JCAS_69_23","DOIUrl":"10.4103/JCAS.JCAS_69_23","url":null,"abstract":"<p><strong>Introduction: </strong>Peeling has withstood the test of time as a simple, minimally invasive method to renew the skin, despite the introduction of more advanced procedures like lasers.</p><p><strong>Materials and methods: </strong>Thirty patients (or 60 sites) with age ranging from 15 to 45 years with mild-to-moderate acne vulgaris were included in the study. Assessment at baseline was done by the global acne grading system score for including mild and moderate acne patients.</p><p><strong>Results: </strong>On grading the improvement according to the 5-point Global Assessment Scale (GAS), it was found that in area A (black peel), 6.7% of patients showed excellent improvement, 86.7% of patients showed good improvement, and 6.7% of patients showed fair improvement. In area B (25%TCA peel), 6.7% of patients showed excellent improvement, 80% of patients showed good improvement, and 13.3% of patients showed fair improvement.</p><p><strong>Discussion: </strong>None of the patients showed poor or worse outcomes in any of the areas. The difference between the groups was not significant (<i>P =</i> 0.688).</p><p><strong>Conclusion: </strong>There is a paucity of data in the literature regarding the comparison of black peel with other conventional peels in the treatment of acne vulgaris. To the best of our knowledge, this is the first study comparing black peel with TCA peel in the treatment of acne vulgaris.</p>","PeriodicalId":15415,"journal":{"name":"Journal of Cutaneous and Aesthetic Surgery","volume":"17 1","pages":"11-18"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11086936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140911819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Cutaneous and Aesthetic Surgery
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