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Efficacy of fractional carbon dioxide laser-assisted drug delivery in the management of post-burn scars - A prospective study. 点阵二氧化碳激光辅助给药治疗烧伤后疤痕的疗效--一项前瞻性研究。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/jcas_181_23
Shekhar Neema, Senkadhir Vendhan, Biju Vasudevan, Lekshmipriya K, Senkadhirdasan Dakshinamurthy

Objectives: The objective of our study is to assess the efficacy of fractional carbon dioxide (CO2) laser-assisted drug delivery (LADD) in the management of post-burn scars.

Material and methods: It is a prospective study conducted from March 2021 to February 2022, with 32 patients ranging in age from 9 to 52 years. The scars lasted anywhere from 6 months to 18 years. The ethical clearance of the Institutional Ethics Committee was obtained. The patient's median age was 22 (range, 09-52). Patients were assessed using a modified Vancouver scar scale (mVSS) score before and after receiving fractional CO2 laser at monthly intervals.

Results: After one treatment, statistically significant improvements in pigment, thickness, and pliability were seen according to the mVSS scores, and these improvements persisted through the final laser session.

Conclusion: Our study has demonstrated that fractional CO2 LADD seems to be an encouraging approach in the management of post-burn scars with good patient satisfaction.

研究目的我们的研究旨在评估点阵二氧化碳(CO2)激光辅助给药(LADD)治疗烧伤后疤痕的疗效:这是一项前瞻性研究,研究时间为 2021 年 3 月至 2022 年 2 月,共有 32 名患者参加,年龄从 9 岁到 52 岁不等。疤痕持续时间从 6 个月到 18 年不等。研究获得了机构伦理委员会的伦理许可。患者的中位年龄为 22 岁(09-52 岁)。患者在接受点阵 CO2 激光治疗之前和之后,每月接受一次改良温哥华疤痕量表(mVSS)评分:结果:经过一次治疗后,根据 mVSS 评分,色素、厚度和柔韧度都有了统计学意义上的显著改善,这些改善一直持续到最后一次激光治疗:我们的研究表明,点阵二氧化碳激光治疗烧伤后疤痕似乎是一种令人鼓舞的方法,患者满意度很高。
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引用次数: 0
Intralesional chemical cautery of papulonodular acne. 乳头状痤疮的区域内化学烧灼疗法。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2022-12-02 DOI: 10.4103/JCAS.JCAS_129_22
Muhammed Mukhtar
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引用次数: 0
A keen eye for detailed observation. 敏锐的观察力
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/JCAS_61_2024
Uwe Wollina
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引用次数: 0
Giant trichilemmal cyst of scrotum. 阴囊巨大三叶囊肿。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2022-12-02 DOI: 10.4103/JCAS.JCAS_43_21
Anirudha D Gulanikar, Omkar S Kulkarni, Jiten Kulkarni, Nikhil Reddy

A 45-year-old man with an asymptomatic lesion on the scrotum since 25 years presented to the skin out patient department (OPD). There were multiple skin-colored to hyperpigmented nodules with areas of calcification on the scrotum. The mass measured 20 cm × 10 cm × 8 cm as a whole. Steatocystoma was clinically diagnosed and excision of the lesion was performed by a plastic surgeon. The mass was removed en masse and the removed specimen was measured to be 20 cm × 10 cm × 5 cm. On histopathological examination, the cysts showed epithelium resembling that of outer hair root sheath. Contents of the cysts were homogenous unlamellated keratin with focal calcification.

一名 45 岁男子的阴囊自 25 年前开始出现无症状病变,后来到皮肤门诊部(OPD)就诊。阴囊上有多个皮肤色至色素沉着的结节,并伴有钙化区域。肿块整体大小为 20 厘米×10 厘米×8 厘米。经临床诊断为脂肪囊肿,整形外科医生对病灶进行了切除。肿块被整体切除,切除标本的尺寸为 20 cm × 10 cm × 5 cm。组织病理学检查显示,囊肿的上皮与外发根鞘相似。囊肿内容物为均质无细胞角蛋白,伴局灶性钙化。
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引用次数: 0
Therapeutic pearl: A simple cost-effective treatment for chronic digital intertrigo of toes. 治疗珍珠:治疗慢性脚趾骨间膜炎的经济有效的简单疗法。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2022-12-02 DOI: 10.4103/JCAS.JCAS_127_21
Muhammed Mukhtar, Nadia Mukhtar

Chronic intertrigo of toe-web space is a recalcitrant problem which is often associated with multi-organism infections. For this, a number of topical therapies with preventative measures are used, but many of them are cumbersome and not very effective. Cryotherapy is a good option for treating the toe intertrigo, but its availability is a major concern. Here as an alternative to cryotherapy, trichloroacetic acid (TCA) cautery and Sodium hypochlorite (NaOCl) (a broad spectrum anti-infective agent) solution is advocated as a simple, feasible, and cost-effective treatment of chronic inter digital intertrigo.

趾蹼间的慢性趾蹼间皮瘤是一种顽固性问题,通常与多种病原体感染有关。为此,人们采用了许多局部疗法和预防措施,但其中许多都很麻烦,而且效果不佳。冷冻疗法是治疗脚趾间皮瘤的一个不错选择,但其可用性是一个主要问题。作为冷冻疗法的替代疗法,这里提倡使用三氯乙酸(TCA)烧灼法和次氯酸钠(NaOCl)(一种广谱抗感染剂)溶液,这是一种简单、可行且经济有效的治疗慢性足趾间溃疡的方法。
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引用次数: 0
Efficacy and safety of microneedling radiofrequency in patterned hair loss. 微针射频治疗模式化脱发的有效性和安全性。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/jcas_44_23
Balakrishnan Nirmal, S Shahin Mubeena, Belavendra Antonisamy

Objectives: We aimed to assess the improvement of patterned hair loss with microneedling radiofrequency (MNRF) and its adverse effects in patients.

Material and methods: An open-label study was conducted to evaluate the efficacy and safety of MNRF for the treatment of androgenetic alopecia. Patients diagnosed with patterned hair loss received three MNRF treatment sessions once monthly. Efficacy was assessed by comparing before and after photographs and trichoscopy.

Results: Twenty-four patients were recruited. Excellent improvement in hair growth was observed in 14 patients, fair improvement in seven patients, and no improvement in three patients without significant adverse effects. Slight pain lasting for a day was the most common adverse event following MNRF.

Conclusion: Overall, significant improvement was observed in the majority of the patients without significant side effects.

目的:我们旨在评估微针射频治疗模式性脱发的改善效果及其对患者的不良影响:我们旨在评估微针射频治疗模式性脱发的改善效果及其对患者的不良影响:我们进行了一项开放标签研究,以评估微针射频治疗雄激素性脱发的有效性和安全性。被诊断为模式性脱发的患者接受了三次 MNRF 治疗,每月一次。疗效通过比较治疗前后的照片和毛囊镜检查进行评估:结果:共招募了 24 名患者。结果:共招募了 24 名患者,其中 14 名患者的毛发生长得到了很好的改善,7 名患者改善一般,3 名患者没有改善,且无明显不良反应。轻微疼痛持续一天是多发性脱发治疗后最常见的不良反应:总体而言,大多数患者的病情都有明显改善,且无明显副作用。
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引用次数: 0
A unique use of a face mask for photoprotection during Psoralen-UVASol for eyelid and lip vitiligo. 在补骨脂- uvasol治疗眼睑和唇部白癜风期间,使用独特的面膜进行光保护
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2023-06-27 DOI: 10.4103/JCAS.JCAS_147_22
Muhammed Mukhtar
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引用次数: 0
Comparative study in treatment of acne scars fractional carbon dioxide laser versus micro needling fractional radio frequency - A retrospective study. 点阵二氧化碳激光与点阵射频微针治疗痤疮疤痕的比较研究 - 一项回顾性研究。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/jcas_122_23
Rashmi Sriram, B S Chandrashekar, Madura C, Harshavardhan Gowda H

Objectives: Efficacy of fractional carbon dioxide laser and microfractional radiofrequency in treatment of acne scars is well substantiated. The objective of this study was to compare the efficacy and safety of carbon dioxide laser versus microfractional radiofrequency in treatment of acne scars in skin type 3,4.

Material and methods: Thirty-two patients of skin types 3-4 with grade 3 and 4 atrophic acne scars, of which 16 were treated with fractional carbon dioxide (CO2) laser and 16 were treated with microfractional radiofrequency were retrospectively analyzed. All patients received either treatment 4 sessions at an interval of 4-6 weeks. Objective assessment was done with qualitative and quantitative Goodman and baron acne scar grading system by assessment of photographs at baseline and 3 months after last session.

Results: All the data collected were entered in a Microsoft Excel worksheet and analyzed using R Software R-4.2.1. The study variables acne scar grades were described using frequency with percentage, acne scar scores were described using Mean with Standard deviation, and Median with interquartile range (IQR) (Q1-Q3). Since the data were ordinal, which is non-normal, hence, non-parametric tests are applied. To compare grades between the groups, Mann-Whitney U-test was applied.

Conclusion: There was no difference in the last session (after the treatment) between the groups, the Mann- Whitney U-test was 109.5 with P-value of 0.484 >0.05. Therefore, there was no statistically significant difference between the microfractional radiofrequency and carbon dioxide laser group. There were 2 (12.5%) cases reported with post-inflammatory hyperpigmentation in the CO2 laser group and zero cases in the microfractional radiofrequency group.

目的:点阵二氧化碳激光和微点阵射频治疗痤疮疤痕的疗效已得到充分证实。本研究旨在比较二氧化碳激光与微点射频治疗 3、4 类皮肤痤疮疤痕的有效性和安全性:对32名3-4型皮肤的3级和4级萎缩性痤疮疤痕患者进行了回顾性分析,其中16名患者接受了点阵二氧化碳(CO2)激光治疗,16名患者接受了微点射频治疗。所有患者均接受了其中一种治疗方法,治疗 4 次,每次间隔 4-6 周。通过对基线和最后一次治疗后 3 个月的照片进行评估,采用古德曼和巴隆痤疮疤痕分级系统进行定性和定量客观评估:收集到的所有数据均输入 Microsoft Excel 工作表,并使用 R 软件 R-4.2.1 进行分析。研究变量痤疮疤痕等级使用频率和百分比进行描述,痤疮疤痕分数使用平均值和标准差以及中位数和四分位数间距(IQR)(Q1-Q3)进行描述。由于数据是非正态的序数,因此采用了非参数检验。为了比较各组之间的成绩,采用了曼-惠特尼 U 检验:各组在最后一次治疗(治疗后)中没有差异,曼-惠特尼 U 检验结果为 109.5,P 值为 0.484 >0.05。因此,微分射频组和二氧化碳激光组在统计学上没有显著差异。二氧化碳激光组有 2 例(12.5%)报告出现炎症后色素沉着,而微点阵射频组为 0 例。
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引用次数: 0
Platelet-rich fibrin therapy in the management of nonhealing trophic ulcers due to underlying leprous neuropathy. 富含血小板的纤维蛋白治疗潜在麻风神经病变引起的营养性溃疡
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2023-06-27 DOI: 10.4103/JCAS.JCAS_192_22
Senkadhir Vendhan, Shekhar Neema, Biju Vasudevan, Lekshmipriya Krishnan, Vinay Gera

Autologous platelet-rich fibrin (PRF) therapy is beneficial in the treatment of nonhealing ulcers. We present a case series of nonhealing, trophic ulcers with underlying leprous neuropathy, treated successfully with PRF therapy. It was a prospective study, conducted in a tertiary care hospital in the western Maharashtra, India between April 2021 and March 2022. A total of 11 patients with 18 nonhealing trophic ulcers were included in the study and consisted of 8 men and 3 women. The patient's median age was 41 years (range, 33-68), the median size of the ulcers was 4 cm2 (range: 1-12 cm2), the median duration of ulcers was 20 weeks (16-30 weeks), and time to heal after starting treatment was 4 weeks (range: 1-8 weeks). PRF is an easy-to-use, simple, safe, effective, and economical treatment for the management of trophic ulcers.

自体富血小板纤维蛋白(PRF)疗法有利于治疗不愈合溃疡。我们介绍了一例采用 PRF 疗法成功治疗伴有潜在麻风神经病变的不愈合营养性溃疡的系列病例。这是一项前瞻性研究,于 2021 年 4 月至 2022 年 3 月期间在印度马哈拉施特拉邦西部的一家三级医院进行。研究共纳入了11名患有18处不愈合营养性溃疡的患者,其中男性8人,女性3人。患者年龄中位数为 41 岁(范围:33-68 岁),溃疡面积中位数为 4 平方厘米(范围:1-12 平方厘米),溃疡持续时间中位数为 20 周(16-30 周),开始治疗后痊愈时间为 4 周(范围:1-8 周)。PRF是一种易于使用、简单、安全、有效且经济的治疗营养性溃疡的方法。
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引用次数: 0
Elliptical excision and primary closure of nasal defect to achieve best esthetic outcome: A case series of 50 patients. 椭圆形切除术和鼻缺损的初次闭合以达到最佳美学效果:50 例患者的病例系列。
Q3 Medicine Pub Date : 2024-07-01 Epub Date: 2024-08-29 DOI: 10.25259/jcas_120_23
Yogesh M Bhingradia, Chinmai Yadav, Tejaswini Sopanrao Salunke

Objectives: To evaluate the cosmetic result of nasal of an elliptical excision and primary closure on small nasal defect by using Scar assessment using the Stony Brook Scar Evaluation Scale (SBSES) score.

Material and methods: This retrospective interventional study was conducted in a private clinic over a 2-year duration. Patients aged 18-60 years with nasal defects <1.5 cm were enrolled after obtaining informed consent. Exclusion criteria included immunocompromised status, keloidal tendency, local site infection, bleeding disorder, age <18 years, and lack of consent. Scar assessment using the SBSES was performed at the end of 6 months. Statistical analysis included summary statistics, analysis of variance tests, and a significance level of P < 0.05.

Results: The study included 50 patients, with 54% males and 46% females. The most common age group was 21-40 years, and melanocytic nevi was the most common cause for excision. Lesions were excised mainly from the lateral wall and dorsum of the nose. The mean SBSES score was 3.79 ± 0.467. The best cosmetic outcome was observed in lesions involving the dorsum followed by the root of the nose. No significant difference was found among the SBSES scores for various subunits.

Conclusion: Elliptical excision with primary closure is a simple and effective technique for small nasal defects, providing good cosmetic results. The location of the nasal defect influences the cosmetic outcome, with better results observed in areas with thinner skin and increased skin laxity.

目的通过使用石溪瘢痕评估量表(SBSES)进行瘢痕评估,评估鼻部椭圆形切除术和鼻部小缺损一次闭合术的美容效果:这项回顾性干预研究在一家私人诊所进行,为期两年。研究对象为年龄在 18-60 岁之间的鼻腔缺损患者:研究共纳入 50 名患者,其中男性占 54%,女性占 46%。最常见的年龄段为 21-40 岁,黑色素细胞痣是最常见的切除原因。病变主要从鼻侧壁和鼻背切除。平均SBSES评分为(3.79±0.467)分。鼻背病变的美容效果最好,其次是鼻根。不同亚单位的 SBSES 评分无明显差异:结论:椭圆形切除加初次闭合术是治疗鼻部小缺损的一种简单而有效的技术,具有良好的美容效果。鼻部缺损的位置会影响美容效果,皮肤较薄和皮肤松弛度较高的部位效果更好。
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引用次数: 0
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Journal of Cutaneous and Aesthetic Surgery
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