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Histopathological Spectrum of Neoplastic Lesions of Female Reproductive System at a Tertiary Care Hospital in Bharatpur, Chitwan Chitwan巴拉特普尔一家三级医院女性生殖系统肿瘤病变的组织病理学谱
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.52017
M. Sedhain, P. Pathak, B. Goyal, Pratigya Subedi
IntroductionMalignant neoplasms of the female genital tract accounts for majority of the cancers in females.The incidence and pattern of malignancies vary from region to region due to differences ingenetic patterns, lifestyle and sociocultural factors. The objective of this research is to study thehistopathological spectrum of neoplastic lesions of female reproductive system.MethodsA total of 309 samples of neoplastic lesions were included in the study from the period of January2017 to December 2021.ResultsMost of the neoplastic lesions were found in the uterine corpus, followed by ovary, breasts, cervixand vulva. 80.25% of the neoplastic lesions were benign and 11.97% were malignant; the rest beingpremalignant and borderline categories.ConclusionsMalignant neoplasms of female genital tract contributes to major cancer burden among women andtherefore special measures should be adopted to reduce its incidence and improve the prognosis
引言女性生殖道恶性肿瘤占女性癌症的大多数。由于遗传模式、生活方式和社会文化因素的差异,恶性肿瘤的发病率和模式因地区而异。本研究的目的是研究女性生殖系统肿瘤病变的病理学谱。方法2017年1月至2021年12月共309例肿瘤性病变样本。结果肿瘤性病变多见于子宫体,其次为卵巢、乳房、宫颈和外阴。肿瘤病变中良性占80.25%,恶性占11.97%;其余的是不一致的和边缘的类别。结论女性生殖道恶性肿瘤是女性癌症主要负担之一,应采取特殊措施降低其发生率,改善预后
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引用次数: 0
Prevalence and Associated Factors of Menstruation Pattern Among Schools Adolescents 学校青少年月经方式的患病率及相关因素
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.53523
M. Prasai, H. Upadhyay, Srijana Panthi, K. Khadka, Roshan Kuwar
IntroductionMenstruation, also known as a period, is a natural process that occurs in the female body as apart of the menstrual cycle. The menstrual cycle is the monthly hormonal cycle that preparesthe female body for pregnancy. The objective of this research is to find the prevalence andassociated factors of menstruation pattern among schools adolescents.MethodsA descriptive cross sectional study was conducted among 355 adolescent girls of (10-19 years) in five boarding and government school of Bharatpur municipality, Chitwan. Self- structure questionnaire was then distributed to those students who had already attended their menstruation. Data was entered and analyse by using descriptive and inferential statistical tools in SPSS 20. P-value <0.05 were considered as statistically significant.ResultsThe mean±SD of age was found 14.60±1.54 years. In 63.9% (With 95 %CI 58.9% to 68.9%)students had irregular menstruation cycle. Likewise18.87% students had Oligomenorrhoea,17.18% had Polymenorrhoea and 11.3% students had menorrhagia. Family history of studentswas found as statistically significant with menstruation problem (p-value<0.05).ConclusionsDysmenorrhea, Irregularities in menstruations cycle and Pre menstruation symptoms wasfound to be major problems in adolescents girls.
引言月经,也被称为经期,是女性身体中作为月经周期的一部分发生的一个自然过程。月经周期是女性为怀孕做准备的每月荷尔蒙周期。本研究的目的是了解在校青少年月经方式的患病率及其相关因素。方法对奇特旺市巴拉特布尔市五所寄宿制和公立学校的355名10-19岁少女进行描述性横断面研究。然后将自我结构问卷分发给那些已经来月经的学生。使用SPSS 20中的描述性和推断性统计工具对数据进行输入和分析。P值<0.05被认为具有统计学意义。结果年龄平均±SD为14.60±1.54岁。63.9%(95%CI为58.9%至68.9%)的学生月经周期不规律。与此类似,18.87%的学生患有月经过少,17.18%的学生患有多发性甲状腺肿,11.3%的学生患有痛经。学生的家族史与月经问题具有统计学意义(p值<0.05)。结论痛经、月经周期不规律和月经前症状是少女的主要问题。
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引用次数: 0
Awareness and Practice Patterns Among Pediatricians Regarding Retinopathy of Prematurity at Bharatpur, Chitwan, Nepal 尼泊尔奇旺巴拉特普尔儿科医生对早产儿视网膜病变的认识和实践模式
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.48990
M. Shrestha, Puspa Giri Shrestha, R. Sah, K. Subedi
IntroductionRetinopathy of prematurity (ROP) is a disorder of the developing retina of preterm infants dueto defective vasculogenesis that can lead to incurable blindness. It can be prevented by timelydetection and treatment. The study aimed to analyze the level of awareness, knowledge andpractice of Pediatricians regarding ROP in Bharatpur.MethodsThis was a quantitative, cross-sectional study using self-administered questionnaires to assess theawareness level among pediatricians at the main hospitals of Bharatpur City. A scoring system wasimplemented in the data analysis, depending on the correct chosen answers on the questionnaire.The ethical approval was obtained from the Institutional Review Committee of NNJS (Reg. no. 15/2022).ResultsForty-three pediatricians from 11 hospitals in Bharatpur Metropolitan City filled out thequestionnaires. The mean age of the participants was 35.53 ± 9.09 years (25 to 68 years), majoritybeing male (N=28; 65.12%). More than half of the participants, 23 (53.49%) had a knowledge scoreof 10-15. The knowledge score was 0-5 and >20 in 6 (13.95%) and 2(4.65%) participants respectively.Men were significantly more knowledgeable about ROP than women (p = 0.02).ConclusionsThis study has projected the level of understanding about ROP among pediatricians in Bharatpur.Workshops and courses on ROP screening criteria and referral are recommended specificallyfor pediatric residents and pediatricians in the early stages of their careers. There should becoordination and good referral network between Pediatricians and Ophthalmologists.
早产儿视网膜病变(ROP)是一种由于血管生成缺陷导致的早产儿视网膜发育障碍,可导致无法治愈的失明。它可以通过及时检测和治疗来预防。本研究旨在分析巴拉特布尔儿科医生对ROP的认识、知识和实践水平。方法这是一项定量、横断面的研究,使用自填问卷来评估巴拉特布尔市主要医院儿科医生的意识水平。在数据分析中,根据问卷上正确选择的答案,采用了评分系统。伦理批准获得了NNJS机构审查委员会的批准(注册号15/2022)。结果来自巴拉特布尔市11家医院的43名儿科医生填写了问卷。参与者的平均年龄为35.53±9.09岁(25至68岁),大多数为男性(N=28;65.12%)。超过一半的参与者,23人(53.49%)的知识得分为10-15。6名(13.95%)和2名(4.65%)参与者的知识得分分别为0-5和>20。男性对ROP的了解明显高于女性(p=0.02)。结论本研究预测了巴拉特布尔儿科医生对ROP了解的水平。专门为处于职业生涯早期的儿科住院医师和儿科医生推荐关于ROP筛查标准和转诊的研讨会和课程。儿科医生和眼科医生之间应该有协调和良好的转诊网络。
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引用次数: 0
Clinical Characteristics and Results of Transungual Excision of Subungual Glomus Tumor 蹄下肾小球肿瘤经蹄切除术的临床特点及疗效
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.49319
S. Pandey
IntroductionGlomus tumor is rare and subungual location of the distal phalanx is the most common site. Surgical excision is the mainstay of treatment to relieve the symptoms. The objective of this study was to analyze the clinical characteristics and result of transungual excision of the tumor.MethodsA retrospective cross sectional study of was conducted among 15 cases of subungual glomus tumors operated with transungual excision over 8 years period in the department of Orthopedics. The clinical and demographic characteristics were noted from the case record. The outcome variables were assessed from case records, OPD visits, and telephone interviews and the results analyzed were pain relief, postoperative recurrence, nail deformity, and patient satisfaction. Data was analyzed by using descriptive statistical tools in SPSS-20.ResultsThe mean age of the patients was 32.6 years with the mean duration of symptoms 1.8 years. The mean tumor size was 3.4 mm. Pain and pinpoint tenderness were present in all 15 cases and positive cold sensitivity test and positive Hildreth’s test in 13 (86.7%) and 10 (66.7%) cases respectively. All cases had complete relief of pain within 2 weeks of the operation. There was no case of recurrence and nail deformity till a minimum of 1 year of follow up.ConclusionsThe diagnostic clinical triad of pain, point tenderness, and cold sensitivity are the most common findings. The transungual excision of the tumor can give rise to excellent results with complete relief of pain in all cases with no recurrence or nail deformity.
骨部肿瘤是罕见的,趾下位置的远端指骨是最常见的位置。手术切除是缓解症状的主要治疗方法。本研究的目的是分析经舌切除肿瘤的临床特点和结果。方法对骨科8年来收治的15例经趾下血管球瘤行经趾切除的病例进行回顾性横断面分析。从病例记录中记录临床和人口学特征。结果变量从病例记录、门诊就诊和电话访谈中评估,结果分析为疼痛缓解、术后复发、指甲畸形和患者满意度。采用SPSS-20的描述性统计工具对数据进行分析。结果患者平均年龄32.6岁,平均症状持续时间1.8年。平均肿瘤大小为3.4 mm。15例患者均出现疼痛和针尖压痛,冷敏试验阳性13例(86.7%),Hildreth试验阳性10例(66.7%)。所有病例均在术后2周内疼痛完全缓解。随访至少1年,无复发及甲部畸形。结论疼痛、穴位压痛和冷敏感是诊断性临床三联征中最常见的表现。经舌切除肿瘤可获得良好的效果,在所有病例中疼痛完全缓解,无复发或指甲畸形。
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引用次数: 0
An Early Experience of “Hanging Maneuver of Liver resection":A Cross-Sectional Study “悬挂式肝切除术”的早期经验:横断面研究
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.50893
Sagar Khatiwada, N. Belbase, Nishnata Koirala, Sushim Bhujel, Nischal Shrestha, S. Baral, H. Upadhyay
Introduction The posterior approach to liver resection is technically difficult, especially when there is a bulky tumor or dense adhesion of right lobe of liver with the risk of tumor dissemination and hepatic vein avulsion. To prevent this, anterior approach of liver resection was used; however, it is technically challenging and can lead to a false line of transection and difficulty in controlling bleeding in deeper parenchymal plane. These technical difficulties are overcome by hanging maneuver liver resection which eases the process of anterior approach. The Objectives of our study were to observe the technical safety, operative duration, operative blood loss, and perioperative complications of hanging maneuver in liver resection.MethodsThis is a cross-sectional study on the patients who underwent hanging maneuver of liver resection at our center. The perioperative data were analyzed. Descriptive variables were described using frequency and percentage; continuous variables were described using mean and standard deviation.ResultsA total of 15 patients underwent hanging maneuver of liver resection, majority were male (66.6%) with Child-Pugh score-A of 80%. The most common indication was complex hydatid cyst of liver (33%) and biliocutaneous fistula (13%) that occurred after previous intervention for hydatid cyst of liver (13%). Intraoperative blood loss was 750±343.2 ml and complications grade IIIA were up to 20% as per Clavien Dindo grading system.ConclusionsHanging maneuver of liver resection is a technique that facilitates in elevating liver parenchyma away from IVC and helps in an easier anterior approach. A learning curve and assessment of background liver disease is necessary for its safety. 
肝后入路切除在技术上是困难的,特别是当肿瘤体积大或肝右叶致密粘连时,有肿瘤播散和肝静脉撕脱的危险。为防止这种情况,采用肝前路切除;然而,在技术上具有挑战性,并可能导致假横切线和难以控制深部实质面出血。悬挂式肝切除术简化了前路手术过程,克服了这些技术上的困难。我们的研究目的是观察悬挂手法在肝切除术中的技术安全性、手术时间、术中出血量及围手术期并发症。方法对我院行悬挂式肝切除术的患者进行横断面研究。分析围手术期资料。描述性变量用频率和百分比来描述;连续变量用均值和标准差来描述。结果15例患者行悬挂式肝切除术,男性占66.6%,Child-Pugh评分为80%。最常见的适应症是复杂肝包虫病(33%)和既往干预肝包虫病(13%)后发生的胆皮瘘(13%)。术中出血量750±343.2 ml,并发症按Clavien Dindo分级IIIA级占20%。结论尚青手法是一种能使肝实质远离下腔静脉的方法,有利于前路手术。学习曲线和背景肝病的评估对其安全性是必要的。
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引用次数: 0
Prevalence of Bullying in Undergraduate Students at a Medical College of Nepal 尼泊尔一所医学院本科生恃强凌弱的普遍程度
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.47943
Mukta Singh Bhandari, J. Chataut
IntroductionBullying is a common problem affecting physical and mental health as well as academic performance of students. It also results in harmful coping behaviours like indulgence in alcohol, drug abuse and college drop out. Compared to students from other streams, the proportion of bullying among medical students is very high. The objective of this study was to determine the prevalence of bullying among students in a medical college of Nepal.MethodsA cross-sectional study was carried out amongst students of Kathmandu University School of Medical Sciences, enrolled in MBBS stream during the period of September 2021 to July 2022. Ethical approval was taken from Institutional review committee of the institute (Approval number: 76/2021). A semi-structured, self-administered questionnaire was used. Descriptive statistics were performed and Chi-square Test was done.ResultsThe prevalence of bullying in this study was 78% (203) and 145 (71%) of the victims were male. Verbal bullying by classmates and others was 153 (75%) while non-verbal bullying by teacher/ instructor was 120 (59%). Only 50 (24%) had ever complained about bullying and out of 50 complains, 27 (54%) said action was taken but bullying didn't stop in 33 (66%) of the cases. Out of 156 students who didn't complain, 57 (37%) students felt that it was not a big issue.ConclusionsBullying is a very common problem among medical students however most of the students take it lightly and no action is taken after complaining. Thus, students should be made aware about bullying and serious action should be taken against it.
欺凌是影响学生身心健康和学习成绩的常见问题。它还会导致有害的应对行为,如酗酒、滥用药物和大学辍学。与其他学科的学生相比,医学生中的欺凌比例非常高。本研究的目的是确定尼泊尔一所医学院学生恃强凌弱的普遍程度。方法对2021年9月至2022年7月在加德满都大学医学院MBBS专业入学的学生进行横断面研究。伦理批准由研究所机构审查委员会(批准号:76/2021)批准。采用半结构化、自我管理的问卷。进行描述性统计和卡方检验。结果本研究中欺凌行为的发生率为78%(203),男性占145(71%)。同学和他人的言语欺凌153例(75%),老师/辅导员的非言语欺凌120例(59%)。只有50人(24%)曾经抱怨过欺凌,在50个投诉中,27人(54%)表示采取了行动,但33人(66%)的欺凌行为没有停止。在156名没有抱怨的学生中,57名(37%)学生认为这不是一个大问题。结论:医学生恃强凌弱是一个非常普遍的问题,但大多数学生对其轻描淡写,投诉后不采取任何行动。因此,学生应该意识到欺凌行为,并对其采取严肃的行动。
{"title":"Prevalence of Bullying in Undergraduate Students at a Medical College of Nepal","authors":"Mukta Singh Bhandari, J. Chataut","doi":"10.3126/jcmsn.v19i1.47943","DOIUrl":"https://doi.org/10.3126/jcmsn.v19i1.47943","url":null,"abstract":"IntroductionBullying is a common problem affecting physical and mental health as well as academic performance of students. It also results in harmful coping behaviours like indulgence in alcohol, drug abuse and college drop out. Compared to students from other streams, the proportion of bullying among medical students is very high. The objective of this study was to determine the prevalence of bullying among students in a medical college of Nepal.MethodsA cross-sectional study was carried out amongst students of Kathmandu University School of Medical Sciences, enrolled in MBBS stream during the period of September 2021 to July 2022. Ethical approval was taken from Institutional review committee of the institute (Approval number: 76/2021). A semi-structured, self-administered questionnaire was used. Descriptive statistics were performed and Chi-square Test was done.ResultsThe prevalence of bullying in this study was 78% (203) and 145 (71%) of the victims were male. Verbal bullying by classmates and others was 153 (75%) while non-verbal bullying by teacher/ instructor was 120 (59%). Only 50 (24%) had ever complained about bullying and out of 50 complains, 27 (54%) said action was taken but bullying didn't stop in 33 (66%) of the cases. Out of 156 students who didn't complain, 57 (37%) students felt that it was not a big issue.ConclusionsBullying is a very common problem among medical students however most of the students take it lightly and no action is taken after complaining. Thus, students should be made aware about bullying and serious action should be taken against it.","PeriodicalId":15436,"journal":{"name":"Journal of College of Medical Sciences-nepal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43410919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Histopathological Artifacts in Oral Biopsy Specimen: A Descriptive Cross Sectional Study 口腔活检标本组织病理学伪影分析:描述性横断面研究
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.44310
P. Poudel, Bhoj Raj Adhikari
IntroductionArriving at the final diagnosis requires the histopathological examination of the biopsied lesion. Many a times, diagnosis of lesion may be hindered due to presence of artifacts in the slide. Having a thorough knowledge of these artifacts help to take the precautionary measures to avoid their occurrence. This study is an attempt to analyze histopathological slides from Department of Oral Pathology to identify the artifacts seen in oral biopsy specimens.MethodsThis cross sectional study was conducted in Department of Oral Pathology, Dhulikhel Hospital from July 2021 to February 2022. Slides of all the biopsies during the study period were included in the study. The artifacts were divided into three groups: Artifacts related to surgeons performance, artifacts related to technicians performance and artifacts caused during transfer of sample to the laboratory. Then, the frequency distribution for each type of artifact was calculated.ResultsA total of 280 slides were included in the present study. Artifacts related to technicians performance were seen in 89.3% slides whereas artifacts related to surgeons performance were seen in 76.4% slides. None of the slides showed artifacts related to transfer of sample to the laboratory. The most common artifact seen was eosin leaching (63.6%) followed by stain deposit (60%) and folds and wrinkles (40.7%).ConclusionsThe findings of our study showed that various types of artifacts may be incorporated in biopsy specimen that create difficulty in diagnosing the lesion properly. Proper biopsy protocol and careful handling of sample to prevent technical errors may be helpful to reduce the frequency of artifacts. 
引言最终诊断需要对活检病变进行组织病理学检查。很多时候,由于载玻片中存在伪影,病变的诊断可能会受到阻碍。对这些文物有全面的了解有助于采取预防措施来避免它们的发生。本研究试图分析口腔病理学系的组织病理学切片,以确定口腔活检标本中出现的伪影。方法本横断面研究于2021年7月至2022年2月在杜利克尔医院口腔病理科进行。研究期间的所有活组织切片均包含在研究中。人工制品分为三组:与外科医生表现相关的人工制品、与技术人员表现相关的手工制品以及将样本转移到实验室过程中产生的人工制品。然后,计算每种类型的伪影的频率分布。结果本研究共纳入280张载玻片。89.3%的幻灯片中出现了与技术人员表现相关的伪影,而76.4%的幻灯片中看到了与外科医生表现相关的假影。没有一张幻灯片显示与将样本转移到实验室有关的伪影。最常见的伪影是曙红浸出(63.6%),其次是色斑沉积(60%)和褶皱和皱纹(40.7%)。结论我们的研究结果表明,活检标本中可能存在各种类型的伪影,这给正确诊断病变带来了困难。正确的活检方案和仔细处理样本以防止技术错误可能有助于减少伪影的频率。
{"title":"Analysis of Histopathological Artifacts in Oral Biopsy Specimen: A Descriptive Cross Sectional Study","authors":"P. Poudel, Bhoj Raj Adhikari","doi":"10.3126/jcmsn.v19i1.44310","DOIUrl":"https://doi.org/10.3126/jcmsn.v19i1.44310","url":null,"abstract":"Introduction\u0000Arriving at the final diagnosis requires the histopathological examination of the biopsied lesion. Many a times, diagnosis of lesion may be hindered due to presence of artifacts in the slide. Having a thorough knowledge of these artifacts help to take the precautionary measures to avoid their occurrence. This study is an attempt to analyze histopathological slides from Department of Oral Pathology to identify the artifacts seen in oral biopsy specimens.\u0000Methods\u0000This cross sectional study was conducted in Department of Oral Pathology, Dhulikhel Hospital from July 2021 to February 2022. Slides of all the biopsies during the study period were included in the study. The artifacts were divided into three groups: Artifacts related to surgeons performance, artifacts related to technicians performance and artifacts caused during transfer of sample to the laboratory. Then, the frequency distribution for each type of artifact was calculated.\u0000Results\u0000A total of 280 slides were included in the present study. Artifacts related to technicians performance were seen in 89.3% slides whereas artifacts related to surgeons performance were seen in 76.4% slides. None of the slides showed artifacts related to transfer of sample to the laboratory. The most common artifact seen was eosin leaching (63.6%) followed by stain deposit (60%) and folds and wrinkles (40.7%).\u0000Conclusions\u0000The findings of our study showed that various types of artifacts may be incorporated in biopsy specimen that create difficulty in diagnosing the lesion properly. Proper biopsy protocol and careful handling of sample to prevent technical errors may be helpful to reduce the frequency of artifacts.\u0000 ","PeriodicalId":15436,"journal":{"name":"Journal of College of Medical Sciences-nepal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45212572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stone Free Rate of Lower Pole Calyceal Stone Versus Other Calyces in Retrograde Intrarenal Surgery 逆行肾内手术中下极肾盏结石与其他肾盏结石的游离率
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.49849
R. Shah, Tika Devi Kandel, D. Adhikari
Background: Miniaturization of endoscopic instruments has gained wide popularity in the treatment of renal calculi. Retrograde intra-renal surgery (RIRS) and laser in combination has already proven their superiority when compared to other modalities in the treatment of renal calculi. This study was conducted to assess the stone-free rate (SFR) of lower pole calyceal stone versus other pole calyces in RIRS. Methods:This retrospective study analyzed the stone free rate of lower pole calyx stone versus other pole calyces in retrograde intra renal surgery (RIRS) adults above 15 years of age from March 2021 to February 2022 at Chitwan Medical College and Teaching Hospital, Nepal. The stone-free rate was assessed descriptively on post operative complications, stone size, operative time, hospital stay, and need for the second procedure.Results:A total of 62 patients underwent retrograde intrarenal surgery. The mean age of the study population was 38.41 ± 10.54years in the lower caliceal group against 39.09 ±13.53 years with p value of 0.829.The mean hounsfield of lower caliceal stone was 1023.31±252.96 to that of other caliceal stones 1004.00±349.22 with p value of 0.806. The sizes of the stones were 11.07±2.10 mm in lower caliceal stones versus 10.67±2.51mm in other caliceal stones with p value of 0.507.The duration of operation time in 1st group was 63.82±23.57minutes to that of 65.93±28.96 in 2nd group with p value of 0.756.The hospital stay in lower caliceal stones were 6.13±1.43days to that of other caliceal stones 5.87±0.99 with significant p value of 0.412.There were no major complications in both arms.The stone free rate was 25 (86.2%) in lower caliceal stones as compared to 31(93.93%) in other caliceal stones with no significant p value of 0.405.  Conclusions:Retrograde intrarenal surgery is a better procedure that continues to undergo significant advancements. It is a technically safe and effective procedure for the treatment option for treating the lower pole calyx calculus with optimal post-surgical morbidity and stone-free rate.
背景:内镜器械的小型化在肾结石的治疗中得到了广泛的应用。与其他治疗方式相比,逆行肾内手术(RIRS)和激光联合治疗肾结石已经证明了其优越性。本研究旨在评估RIRS患者下极肾盏结石与其他极肾盏结石的无石率(SFR)。方法:本回顾性研究分析了2021年3月至2022年2月在尼泊尔奇旺医学院和教学医院接受逆行肾内手术(RIRS)的15岁以上成人中,下极肾盏结石与其他极肾盏结石的游离率。对术后并发症、结石大小、手术时间、住院时间和是否需要第二次手术进行描述性评估。结果:62例患者行逆行肾内手术。低钙组平均年龄为38.41±10.54岁,低钙组平均年龄为39.09±13.53岁,p值为0.829。下盏结石的平均hounsfield为1023.31±252.96,其他盏结石的平均值为1004.00±349.22,p值为0.806。下盏结石大小为11.07±2.10 mm,其他盏结石大小为10.67±2.51mm, p值为0.507。第一组手术时间为63.82±23.57min,第二组为65.93±28.96 min, p值为0.756。下盏结石住院时间为6.13±1.43天,其他盏结石住院时间为5.87±0.99天,p值为0.412,差异有统计学意义。两臂均无重大并发症。下盏结石游离率为25(86.2%),其他盏结石游离率为31(93.93%),p值为0.405,差异无统计学意义。结论:逆行肾内手术是一种更好的治疗方法,并不断取得重大进展。这是一种技术上安全有效的治疗方法,治疗下极肾盏结石,术后发病率和结石清除率最佳。
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引用次数: 0
Comparative Study of Serum Vitamin D and Calcium in Patients With and Without Temporomandibular Joint Disorder: An Institutional Study 颞下颌关节紊乱病和非颞下颌关节疾病患者血清维生素D和钙的比较研究
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.49989
Anuja Panthee, A. Panthee, A. Khapung
IntroductionCalcium homeostasis, an essential component of musculoskeletal system requires Vitamin D as its integral element. Many studies have demonstrated the inconclusive association between serum calcium and some factors involved in calcium metabolism such as vitamin D.ObjectivesThe aim of this present study is to evaluate the serum level of vitamin D and calcium in patient with and without Temporo-mandibular Joint disorder (TMDs) and to determine the association of same with age and gender.Methods: An observational, comparative, quantitative, cross sectional study was done over a period of 6 months. Serum analysis of vitamin D and calcium was done for patients, with and without TMDs, visiting Oral and Maxillofacial Surgery (OMFS) Out Patient Department (OPD) from May to october 2022. Data analysis was done using chi square and independent t test.ResultsA total of 200 study participants were included in the study of which 100 (50.00%) had TMDs and 100 (50.00%) did not have those problems. The difference in Vitamin D  level were found statistically significant in those with and without TMJ problems.ConclusionThere was statistically significant association between serum Vitamin D and TMDs whereas there was no association between serum calcium and TMDs.
钙稳态是肌肉骨骼系统的重要组成部分,需要维生素D作为其不可或缺的元素。许多研究表明,血清钙与一些参与钙代谢的因素(如维生素D)之间存在不确定的相关性。本研究的目的是评估患有和不患有颞下颌关节紊乱病(TMDs)的患者的血清维生素D和钙水平,并确定其与年龄和性别的相关性。方法:进行为期6个月的观察、比较、定量、横断面研究。对2022年5月至10月访问口腔颌面外科门诊部(OPD)的患有和不患有TMDs的患者进行维生素D和钙的血清分析。数据分析采用卡方检验和独立t检验。结果共有200名研究参与者参与了这项研究,其中100人(50.00%)患有TMDs,100人(50.0%)没有这些问题。在有TMJ问题和没有TMJ问题的人群中,维生素D水平的差异具有统计学意义。结论血清维生素D与TMDs有统计学意义,而血清钙与TMDs无相关性。
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引用次数: 0
Outcome of Covid-19 Patients Admitted in Emergency Department of Karnali Academy of Health Sciences, Teaching Hospital 卡纳利卫生科学院教学医院急诊科收治新冠肺炎患者的结果
Pub Date : 2023-05-01 DOI: 10.3126/jcmsn.v19i1.53330
T. Krishna Gupta, Kushal Bhattarai, A. Pal, Smriti Mayur Kasaudhan, N. Manandhar
IntroductionCOVID-19, a global health problem, was first identified in the Hubei province, China.  While various clinical features of the diseases have been documented, the complete clinical profile is yet to be understood. The purpose of this study is to evaluate the outcome of Covid-19 after admission in the emergency of KAHS during the year 2021January – 2022 January.MethodsThis is a hospital-based, retrospective, observational study done in the emergency department of Karnali Academy of Health Sciences (KAHS), Jumla. The data was taken from the registry, including the record files of patients with Covid-19 admitted in the hospital from 2020 January to 2021 January. The retrieved data was initially entered in an Excel sheet followed by its analysis. We carried out Kaplan Meier survival distribution analysis to determine the survival probability and predictors of Covid-19.ResultsOf the 516 Covid-19 positive patients who were admitted in the hospital, 53.5% were males. For the total patients, the mean duration of hospital stay was 8.02±5.32 days with the proportion of patients who died during treatment being 3.7% (n=19). As described by the Kaplan-Meier curve and the accompanying survival table, the mean survival time of the overall patients was 36.74 days (95% CI=35.6–37.8). Moreover, the cumulative survival rate was seen prominently decreased for older patients and those admitted in the intensive care unit and/or ventilator.ConclusionThe increased mortality rates seen in the older patients and those admitted in critical care setting clearly calls for the importance of proper and timely intervention. 
引言新冠肺炎是一个全球性的健康问题,最早在中国湖北省发现。虽然这些疾病的各种临床特征已被记录在案,但完整的临床特征尚待了解。本研究的目的是评估在2021年1月至2022年1月期间入住KAHS急诊室后新冠肺炎的结果。方法本研究是在Jumla Karnali卫生科学院(KAHS)急诊室进行的一项基于医院的回顾性观察性研究。数据取自注册表,包括2020年1月至2021年1月在该医院住院的新冠肺炎患者的记录文件。检索到的数据最初输入Excel工作表,然后进行分析。我们进行了Kaplan-Meier生存分布分析,以确定Covid-19的生存概率和预测因素。结果在入院的516名Covid-19]阳性患者中,53.5%为男性。总患者的平均住院时间为8.02±5.32天,在治疗期间死亡的患者比例为3.7%(n=19)。如Kaplan-Meier曲线和随附的生存表所述,总体患者的平均生存时间为36.74天(95%CI=35.6–37.8)。此外,老年患者和重症监护室和/或呼吸机患者的累计生存率显著下降。结论老年患者和危重症患者的死亡率增加,这清楚地要求进行适当和及时的干预。
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Journal of College of Medical Sciences-nepal
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