Backgrounds: Carbon monoxide (CO) is an odorless and colorless gas that forms when organic materials burn incompletely. Children are more susceptible to CO poisoning than adults because their respiratory and immune systems are still developing. The systemic immune inflammation index (SII) is a marker that reflects the balance between inflammation and immunity.
Aims: In this study, we investigate the relationship between CO poisoning in children and SII.
Materials and Methods: We conducted a retrospective observational study involving pediatric patients (age
{"title":"Karbon Monoksit Zehirlenmesi Olan Çocuklarda Sistemik İmmün İnflamasyon İndeksinin Prognostik Değeri","authors":"Emine ÖZDEMİR KAÇER","doi":"10.16899/jcm.1347034","DOIUrl":"https://doi.org/10.16899/jcm.1347034","url":null,"abstract":"Backgrounds: Carbon monoxide (CO) is an odorless and colorless gas that forms when organic materials burn incompletely. Children are more susceptible to CO poisoning than adults because their respiratory and immune systems are still developing. The systemic immune inflammation index (SII) is a marker that reflects the balance between inflammation and immunity.
 Aims: In this study, we investigate the relationship between CO poisoning in children and SII.
 Materials and Methods: We conducted a retrospective observational study involving pediatric patients (age","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Aim: In the study, the role of Spexin (SPX) and TRPM2 in the protective effect of Hydroxytyrosol (HT) in rats given Corn Syrup was evaluated.
Material and Method: The rats were divided into 4 groups (6 rats in each) (Control, HT, Corn Syrup, Corn Syrup +HT). Rats were given 30% Corn Syrup with drinking water for 6 weeks. 4 ml/kg/day liquid containing HT was applied by oral gavage alone and together with Corn Syrup for 6 weeks. Molecular parameters SPX and TRPM2 were examined histopathologically in liver tissue.
Results: The SPX levels decreased and the TRPM2 levels increased more in the Corn Syrup given Group than the Control Group. SPX levels increased and TRPM2 levels decreased after HT treatment. In the HT Group only, no differences were detected when compared to the control Group.
Conclusion: SPX and TRPM2 may mediate the protective effect of HT on the liver in rats given corn syrup.
{"title":"Liver Protection of Hydroxytyrosol Mediated by Spexin and TRPM2","authors":"Elif ONAT, Nevin KOCAMAN","doi":"10.16899/jcm.1352503","DOIUrl":"https://doi.org/10.16899/jcm.1352503","url":null,"abstract":"Background/Aim: In the study, the role of Spexin (SPX) and TRPM2 in the protective effect of Hydroxytyrosol (HT) in rats given Corn Syrup was evaluated.
 Material and Method: The rats were divided into 4 groups (6 rats in each) (Control, HT, Corn Syrup, Corn Syrup +HT). Rats were given 30% Corn Syrup with drinking water for 6 weeks. 4 ml/kg/day liquid containing HT was applied by oral gavage alone and together with Corn Syrup for 6 weeks. Molecular parameters SPX and TRPM2 were examined histopathologically in liver tissue. 
 Results: The SPX levels decreased and the TRPM2 levels increased more in the Corn Syrup given Group than the Control Group. SPX levels increased and TRPM2 levels decreased after HT treatment. In the HT Group only, no differences were detected when compared to the control Group.
 Conclusion: SPX and TRPM2 may mediate the protective effect of HT on the liver in rats given corn syrup.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT Aim: The aim of this study is retrospective evaluation of the frequency of rotavirus and adenovirus in stool, and their distribution according to gender, age and seasons in children with diarrhea admitted at outpatients or hospitalized in our hospital. Material and Methods: Stool samples of patients aged between 0-18 years received at the Medical Microbiology Laboratory between 2021–2022 were evaluated for rotavirus–adenovirus. Rotavirus and adenovirus antigens were determined qualitatively by immunochromatographic cassette test method. Chi-square test was used in the statistical analysis. Results: A total of 1148 stool samples of pediatric patients were received by our laboratory during these two years for rotavirus and adenovirus antigen test. Of 1148 patients, 8.6% were positive for rotavirus, 5.1% for adenovirus, and 0.6% for both rotavirus and adenovirus antigens. Rotavirus and adenovirus was positive in 7.2% and 5.6% of males, respectively, and 10.6% and 4.5% of females, and there were no statistically significant differences. Rotavirus was most frequently found in the age group 3-5 years (11.6%) and adenovirus was most frequently found in the age group 6-9 years (8.4%), with no significant difference. Rotavirus was most frequently detected in spring (12.9%) while adenovirus was found most frequently in winter (8.1%), without significant differences. Antigen positivity was 4.1% and 4.9% in outpatients for rotavirus and adenovirus, respectively, and 15.1% and 5.5% in hospitalized patients. Rotavirus positivity was significantly higher in hospitalized patients than outpatients, and adenovirus positivity did not show a significant difference. Conclusion: We found that rotavirus and adenovirus were significant agents causing diarrhea in children, especially those younger than 5 years old, and that its frequency increased in winter and spring, and as rotavirus is a cause of hospitalization, implementation of rotavirus vaccine into routine vaccination programs seem to be beneficial for patients.
{"title":"Frequency of Rotavirus and Adenovirus in Children with Diarrhea","authors":"Hülya DURAN, Fadime YILMAZ YÜCEL","doi":"10.16899/jcm.1316829","DOIUrl":"https://doi.org/10.16899/jcm.1316829","url":null,"abstract":"ABSTRACT Aim: The aim of this study is retrospective evaluation of the frequency of rotavirus and adenovirus in stool, and their distribution according to gender, age and seasons in children with diarrhea admitted at outpatients or hospitalized in our hospital. Material and Methods: Stool samples of patients aged between 0-18 years received at the Medical Microbiology Laboratory between 2021–2022 were evaluated for rotavirus–adenovirus. Rotavirus and adenovirus antigens were determined qualitatively by immunochromatographic cassette test method. Chi-square test was used in the statistical analysis. Results: A total of 1148 stool samples of pediatric patients were received by our laboratory during these two years for rotavirus and adenovirus antigen test. Of 1148 patients, 8.6% were positive for rotavirus, 5.1% for adenovirus, and 0.6% for both rotavirus and adenovirus antigens. Rotavirus and adenovirus was positive in 7.2% and 5.6% of males, respectively, and 10.6% and 4.5% of females, and there were no statistically significant differences. Rotavirus was most frequently found in the age group 3-5 years (11.6%) and adenovirus was most frequently found in the age group 6-9 years (8.4%), with no significant difference. Rotavirus was most frequently detected in spring (12.9%) while adenovirus was found most frequently in winter (8.1%), without significant differences. Antigen positivity was 4.1% and 4.9% in outpatients for rotavirus and adenovirus, respectively, and 15.1% and 5.5% in hospitalized patients. Rotavirus positivity was significantly higher in hospitalized patients than outpatients, and adenovirus positivity did not show a significant difference. Conclusion: We found that rotavirus and adenovirus were significant agents causing diarrhea in children, especially those younger than 5 years old, and that its frequency increased in winter and spring, and as rotavirus is a cause of hospitalization, implementation of rotavirus vaccine into routine vaccination programs seem to be beneficial for patients.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: This study aims to ascertain the clinical and pathological factors linked to the outcomes of patients subjected to surgical intervention and postoperative radiotherapy for mucoepidermoid carcinoma (MEC) originating from both major and minor salivary glands in the head and neck region.
Material and Method: In this retrospective review, medical records of 42 patients who underwent surgery and subsequent radiotherapy for localized MEC in the major and minor salivary glands of the head and neck were analyzed to identify clinicopathological determinants of overall survival. Secondary endpoints encompassed local-regional control, distant metastasis-free survival, and disease-free survival.
Results: The median age of the patient cohort was 56 years, comprising 52.4% males and 47.6% females. The median follow-up period spanned 36 months, with a range of 6 to 88 months. All patients underwent curative surgery, followed by adjuvant radiotherapy. The 2-year and 5-year rates for overall survival (OS), local-regional recurrence-free survival (LRFS), distant metastasis-free survival (DMFS), and disease-free survival (DFS) were 92% and 72.6%, 92.2% and 85.6%, 84.8% and 73%, 82% and 67.3%, respectively. Notably, only histologic grade emerged as a statistically significant prognostic factor, influencing both OS (p=0.019), DMFS (p=0.014), and DFS (p=0.044).
Conclusion: The histologic grade of the tumor is the foremost determinant impacting the outcomes of MEC cases. Adjuvant radiotherapy is recommended for high-grade tumors, while its application for low-grade and intermediate-grade tumors should be individualized based on the anticipated risk of recurrence. This underscores the significance of tailoring treatment approaches according to histologic characteristics.
{"title":"Survival Outcomes and Factors Affecting Prognosis in Patients with Head and Neck Region Mucoepidermoid Carcinoma Treated with Adjuvant Radiotherapy","authors":"Mursel DUZOVA, Mustafa AKIN","doi":"10.16899/jcm.1345383","DOIUrl":"https://doi.org/10.16899/jcm.1345383","url":null,"abstract":"Aim: This study aims to ascertain the clinical and pathological factors linked to the outcomes of patients subjected to surgical intervention and postoperative radiotherapy for mucoepidermoid carcinoma (MEC) originating from both major and minor salivary glands in the head and neck region.
 Material and Method: In this retrospective review, medical records of 42 patients who underwent surgery and subsequent radiotherapy for localized MEC in the major and minor salivary glands of the head and neck were analyzed to identify clinicopathological determinants of overall survival. Secondary endpoints encompassed local-regional control, distant metastasis-free survival, and disease-free survival.
 Results: The median age of the patient cohort was 56 years, comprising 52.4% males and 47.6% females. The median follow-up period spanned 36 months, with a range of 6 to 88 months. All patients underwent curative surgery, followed by adjuvant radiotherapy. The 2-year and 5-year rates for overall survival (OS), local-regional recurrence-free survival (LRFS), distant metastasis-free survival (DMFS), and disease-free survival (DFS) were 92% and 72.6%, 92.2% and 85.6%, 84.8% and 73%, 82% and 67.3%, respectively. Notably, only histologic grade emerged as a statistically significant prognostic factor, influencing both OS (p=0.019), DMFS (p=0.014), and DFS (p=0.044).
 Conclusion: The histologic grade of the tumor is the foremost determinant impacting the outcomes of MEC cases. Adjuvant radiotherapy is recommended for high-grade tumors, while its application for low-grade and intermediate-grade tumors should be individualized based on the anticipated risk of recurrence. This underscores the significance of tailoring treatment approaches according to histologic characteristics.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim:
The internet is a popular and continually utilized platform to gain medical knowledge for patients and health professionals. This research aimed to evaluate the accuracy and quality of videos for premature ventricular contraction (PVC) on YouTube.
Material and method: The keyword "premature ventricular contraction" was inputted into the YouTube search engine. The 60 most watched videos on YouTube were analyzed. Six of these were excluded from the study. A total of 54 patients were included in the study. General characteristics of the videos were recorded. Two specialist physicians reviewed all videos. GQS, DISCERN, and JAMA scoring systems were used to test the video quality and reliability. Video quality was divided into three groups according to the GQS score. Video characteristics were compared between quality groups.
Results: 37% of the videos posted were from doctors, and the most frequently seen content was related to general information about PVCs, accounting for 70.4%. There were 24 high-quality videos. The number of video comments (p=0.006), daily view rate (p=0.001), JAMA (p=
{"title":"Prematüre erken kontraksiyon ile ilgili YouTube videolarının kalite ve güvenilirliğinin değerlendirilmesi","authors":"Kemal GÖÇER","doi":"10.16899/jcm.1342668","DOIUrl":"https://doi.org/10.16899/jcm.1342668","url":null,"abstract":"Aim: 
 The internet is a popular and continually utilized platform to gain medical knowledge for patients and health professionals. This research aimed to evaluate the accuracy and quality of videos for premature ventricular contraction (PVC) on YouTube.
 Material and method: The keyword \"premature ventricular contraction\" was inputted into the YouTube search engine. The 60 most watched videos on YouTube were analyzed. Six of these were excluded from the study. A total of 54 patients were included in the study. General characteristics of the videos were recorded. Two specialist physicians reviewed all videos. GQS, DISCERN, and JAMA scoring systems were used to test the video quality and reliability. Video quality was divided into three groups according to the GQS score. Video characteristics were compared between quality groups.
 Results: 37% of the videos posted were from doctors, and the most frequently seen content was related to general information about PVCs, accounting for 70.4%. There were 24 high-quality videos. The number of video comments (p=0.006), daily view rate (p=0.001), JAMA (p=","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract
Introduction and Aim: Selective IgE deficiency (SIgED) is currently defined as a significant decrease in serum levels of IgE (≤2 kIU/L) in a patient whose other immunoglobulin levels are normal. The clinical spectrum of SIgED is unknown still. This study aimed to determine the relationship between SIgED and autoimmune diseases in an allergy and immunology clinic of a university hospital.
Methods: A retrospective study of the data obtained from medical records of 40 patients, 27 were female (67.5%), and the mean age was 39 years (range 20–69 years) and IgE levels of ≤2.0 kIU/L with normal immunoglobulin (Ig) IgG, IgA, and IgM levels.
Results: A total of 40 patients , 27 females (67.5 %) and 13 males (32.5%), were included in the study. The mean age of the patients was 39 ±13.06 years (range 20–69). In the present study, 35% of patients had an autoimmune disease (N:14), however 65% of patients did not have any autoimmune disease (N:26). Hashimoto’s thyroiditis being the most frequent (N:6) in 15% which is followed by systemic lupus erythematosus (SLE) (N:3) in 7.5%, celiac disease (N: 2) in 5%, chronic spontaneous urticaria (CSU) (N:1) in 2.5%, vitiligo (N:1) in 2.5%, type 1 diabetes mellitus (DM) (N:1) in 2.5%.
Conclusion: SIgED, should be defined clearly with cut-off values of IgE. Physicians should show more attention to the low IgE values and investigate patients about autoimmune diseases which can be seen together with SIgED. More studies should be conducted to investigate associated diseases with SIgED.
{"title":"Selektif IgE Eksikliği ve Otoimmun Hastalık İlişkisi","authors":"Nurhan SAYACA","doi":"10.16899/jcm.1350196","DOIUrl":"https://doi.org/10.16899/jcm.1350196","url":null,"abstract":"Abstract
 Introduction and Aim: Selective IgE deficiency (SIgED) is currently defined as a significant decrease in serum levels of IgE (≤2 kIU/L) in a patient whose other immunoglobulin levels are normal. The clinical spectrum of SIgED is unknown still. This study aimed to determine the relationship between SIgED and autoimmune diseases in an allergy and immunology clinic of a university hospital.
 Methods: A retrospective study of the data obtained from medical records of 40 patients, 27 were female (67.5%), and the mean age was 39 years (range 20–69 years) and IgE levels of ≤2.0 kIU/L with normal immunoglobulin (Ig) IgG, IgA, and IgM levels.
 Results: A total of 40 patients , 27 females (67.5 %) and 13 males (32.5%), were included in the study. The mean age of the patients was 39 ±13.06 years (range 20–69). In the present study, 35% of patients had an autoimmune disease (N:14), however 65% of patients did not have any autoimmune disease (N:26). Hashimoto’s thyroiditis being the most frequent (N:6) in 15% which is followed by systemic lupus erythematosus (SLE) (N:3) in 7.5%, celiac disease (N: 2) in 5%, chronic spontaneous urticaria (CSU) (N:1) in 2.5%, vitiligo (N:1) in 2.5%, type 1 diabetes mellitus (DM) (N:1) in 2.5%. 
 Conclusion: SIgED, should be defined clearly with cut-off values of IgE. Physicians should show more attention to the low IgE values and investigate patients about autoimmune diseases which can be seen together with SIgED. More studies should be conducted to investigate associated diseases with SIgED.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aims: Obsessive compulsive disorder (OCD) is a heterogeneous disorder characterized by obsessions and compulsions. Despite the studies, etiopathogenesis is not fully understood. Pharmacological and psychosocial interventions in OCD may be insufficient due to limited knowledge of etiopathogenesis. Therefore, it is important to find inexpensive and easily determined biochemical parameters related to etiopathogenesis. In this study, the relationship between OCD and vitamin B12 (VitB12), folic acid (FA), vitamin D (VitD) and ferritin was investigated.
Material and Method: 50 patients with OCD (12 female, 38 male) and 50 healthy controls (HC) (13 female, 37 male) were included in this retrospective study. Serum VitB12, FA, ferritin and 25-OH VitD levels of both groups were compared.
Results: VitB12 (p
{"title":"Evaluation of Vitamin B12, Folic Acid, Ferritin and Vitamin D Levels in Obsessive Compulsive Disorder","authors":"Okan İMRE, Rahim KOCABAŞ","doi":"10.16899/jcm.1335202","DOIUrl":"https://doi.org/10.16899/jcm.1335202","url":null,"abstract":"Aims: Obsessive compulsive disorder (OCD) is a heterogeneous disorder characterized by obsessions and compulsions. Despite the studies, etiopathogenesis is not fully understood. Pharmacological and psychosocial interventions in OCD may be insufficient due to limited knowledge of etiopathogenesis. Therefore, it is important to find inexpensive and easily determined biochemical parameters related to etiopathogenesis. In this study, the relationship between OCD and vitamin B12 (VitB12), folic acid (FA), vitamin D (VitD) and ferritin was investigated.
 Material and Method: 50 patients with OCD (12 female, 38 male) and 50 healthy controls (HC) (13 female, 37 male) were included in this retrospective study. Serum VitB12, FA, ferritin and 25-OH VitD levels of both groups were compared.
 Results: VitB12 (p","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The aim of this study is to assess the quality of life and adherence to the Mediterranean diet (MD) among female breast cancer patients.
Material and Method: The study included a cohort of 120 women who received a breast cancer diagnosis within the last year. Anthropometric measurements were conducted, and body composition analysis was carried out to determine body fat percentage. The Mediterranean Diet Adherence Scale (MEDAS) and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) were employed for data collection.
Results: A total of 120 breast cancer patients, with an average age of 49.8±10.56 years, were enrolled in the study. Among these participants, 42.5% were categorized as having a normal weight. The mean waist circumference and waist/hip ratio were 94.6±12.20 cm and 0.87±0.10, respectively. Body fat percentages were determined to be 36.8±8.61%. The average total energy intake was 1944.9±385.24 kcal, with the percentage of total fat intake from energy averaging at 35.6±4.81%. Patients had a mean body mass index (BMI) of 29.0±5.80 kg/m², with 40.8% of them classified as obese. The mean MEDAS score was 7.3±2.65, and the EORTC QLQ-C30 score averaged at 69.7±11.94. There is a negative correlation was found between BMI, waist circumference and MEDAS score; A positive correlation was found between MEDAS scores and EORTC scores.
Conclusion: Breast cancer patients with high compliance with the Mediterranean diet have a higher quality of physical, emotional and social life. Therefore, evaluation of modifiable risk factors in breast cancer patients is essential for the prognosis of the disease.
{"title":"Meme Kanseri Tanısı Almış Kadınlarda Beslenme Durumu, Yaşam Kalitesi ve Akdeniz Diyetine Bağlılığın Değerlendirilmesine İlişkin Bir Araştırma","authors":"Yekta ÇAPALI ŞAHİN, Sine YILMAZ","doi":"10.16899/jcm.1350836","DOIUrl":"https://doi.org/10.16899/jcm.1350836","url":null,"abstract":"Aim: The aim of this study is to assess the quality of life and adherence to the Mediterranean diet (MD) among female breast cancer patients.
 Material and Method: The study included a cohort of 120 women who received a breast cancer diagnosis within the last year. Anthropometric measurements were conducted, and body composition analysis was carried out to determine body fat percentage. The Mediterranean Diet Adherence Scale (MEDAS) and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) were employed for data collection.
 Results: A total of 120 breast cancer patients, with an average age of 49.8±10.56 years, were enrolled in the study. Among these participants, 42.5% were categorized as having a normal weight. The mean waist circumference and waist/hip ratio were 94.6±12.20 cm and 0.87±0.10, respectively. Body fat percentages were determined to be 36.8±8.61%. The average total energy intake was 1944.9±385.24 kcal, with the percentage of total fat intake from energy averaging at 35.6±4.81%. Patients had a mean body mass index (BMI) of 29.0±5.80 kg/m², with 40.8% of them classified as obese. The mean MEDAS score was 7.3±2.65, and the EORTC QLQ-C30 score averaged at 69.7±11.94. There is a negative correlation was found between BMI, waist circumference and MEDAS score; A positive correlation was found between MEDAS scores and EORTC scores.
 Conclusion: Breast cancer patients with high compliance with the Mediterranean diet have a higher quality of physical, emotional and social life. Therefore, evaluation of modifiable risk factors in breast cancer patients is essential for the prognosis of the disease.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract
Aim: The aim of this study was to identify trends in the literature on hysteroscopy and female infertility and to quantitatively evaluate them using various bibliometric parameters.
Material and Methods: The study data was taken from the Web of Science electronic database for this bibliometric network analysis. The network analysis and bibliometric analysis were carried out by using the Biblioshiny and VosViewer bibliometric tools.
Results: A total of 1,023 documents were included in the study. The first article was published in 1977. Until 1990, the annual number of articles was irregular. The quantity of publications published annually significantly increased after 2005, peaking in 2020 and 2021 (68 and 67 articles, respectively). The included articles were published in 67 countries. Among these countries, China (n=299), the USA (n=237), Italy (n=235), and Turkey (n=156) had the highest number of publications. Especially after 2012, there has been a significant increase in Chinese publications. In addition, 10.07% of the documents had co-authors from other countries. The keywords 'hysteroscopy (frequency 422), hysterosalpingography office (frequency 65), hysteroscopy (frequency 49), and chronic endometritis (frequency 45') topped the trending topic list.
Conclusion: It is notable that among international publications, Chinese publications have increased significantly, especially in the last decade. Funding support from Chinese institutions may be responsible for this
{"title":"Global Histeroskopi ve Kadın İnfertilitesi Araştırmalarının Mevcut Durumu: Web of Science Tabanlı Bibliyometrik Analiz Çalışması","authors":"Özgür ŞAHİN","doi":"10.16899/jcm.1343842","DOIUrl":"https://doi.org/10.16899/jcm.1343842","url":null,"abstract":"Abstract
 
 Aim: The aim of this study was to identify trends in the literature on hysteroscopy and female infertility and to quantitatively evaluate them using various bibliometric parameters.
 
 Material and Methods: The study data was taken from the Web of Science electronic database for this bibliometric network analysis. The network analysis and bibliometric analysis were carried out by using the Biblioshiny and VosViewer bibliometric tools.
 
 Results: A total of 1,023 documents were included in the study. The first article was published in 1977. Until 1990, the annual number of articles was irregular. The quantity of publications published annually significantly increased after 2005, peaking in 2020 and 2021 (68 and 67 articles, respectively). The included articles were published in 67 countries. Among these countries, China (n=299), the USA (n=237), Italy (n=235), and Turkey (n=156) had the highest number of publications. Especially after 2012, there has been a significant increase in Chinese publications. In addition, 10.07% of the documents had co-authors from other countries. The keywords 'hysteroscopy (frequency 422), hysterosalpingography office (frequency 65), hysteroscopy (frequency 49), and chronic endometritis (frequency 45') topped the trending topic list.
 
 Conclusion: It is notable that among international publications, Chinese publications have increased significantly, especially in the last decade. Funding support from Chinese institutions may be responsible for this","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract
Objective: Our study focused on retrospectively assessing variant of concern, specified by the World Health Organization (WHO), with one-step reverse transcription and real-time polymerase chain reaction (RT-PCR) test in SARS-CoV-2 positive patients after three doses of attenuated COVID-19 vaccine.
Methods: 8.520 samples transported with viral nucleic acid buffer (vNAT) tubes between June 2021 and January 31, 2022, were tested and included in the study. All the patients whose samples were included in our research had 3 doses of CoronaVac (Sinovac Life Science Co, Ltd, Beijing, China). Gender distribution was 4686 (55%) female and 3834 ( 45%) males. Variant specific genome regions only found in B.1.351, P.1 and B.1.1.7 as well as ORF1ab and N gene regions are investigated by the Bio-Speedy® Emerging Plus kit (Bioeksen AR-GE Technologies, Turkey) used to identify the variants in the study.
Results: All 8.520 samples were SARS-CoV-2 RT-PCR positive. Our study detected alpha and delta variants in 1460 (17.14%) and 3570 (41.9%) patients respectively. 2570 (30.16%) patients did not have any variants according to test results. It was observed that the spread of beta, gamma and other suspicious variants remained at relatively low rates.
Conclusion: The delta variant became dominant from July until to the end of the year. Declining delta variant rates and increasing cases of suspected variants towards the beginning of December 2021 suggest the omicron variant. Therefore, molecular surveillance studies that are planned to take epidemiological data into consideration and to examine the prevalence and gene-based analysis of local and worldwide variants are required.
{"title":"Investigation of Variants In SARS-CoV-2 Infections after Three Doses of COVID-19 Vaccine","authors":"Burcu GÜRER GİRAY, Gökçe GÜVEN AÇIK","doi":"10.16899/jcm.1343574","DOIUrl":"https://doi.org/10.16899/jcm.1343574","url":null,"abstract":"Abstract
 Objective: Our study focused on retrospectively assessing variant of concern, specified by the World Health Organization (WHO), with one-step reverse transcription and real-time polymerase chain reaction (RT-PCR) test in SARS-CoV-2 positive patients after three doses of attenuated COVID-19 vaccine.
 Methods: 8.520 samples transported with viral nucleic acid buffer (vNAT) tubes between June 2021 and January 31, 2022, were tested and included in the study. All the patients whose samples were included in our research had 3 doses of CoronaVac (Sinovac Life Science Co, Ltd, Beijing, China). Gender distribution was 4686 (55%) female and 3834 ( 45%) males. Variant specific genome regions only found in B.1.351, P.1 and B.1.1.7 as well as ORF1ab and N gene regions are investigated by the Bio-Speedy® Emerging Plus kit (Bioeksen AR-GE Technologies, Turkey) used to identify the variants in the study.
 Results: All 8.520 samples were SARS-CoV-2 RT-PCR positive. Our study detected alpha and delta variants in 1460 (17.14%) and 3570 (41.9%) patients respectively. 2570 (30.16%) patients did not have any variants according to test results. It was observed that the spread of beta, gamma and other suspicious variants remained at relatively low rates.
 Conclusion: The delta variant became dominant from July until to the end of the year. Declining delta variant rates and increasing cases of suspected variants towards the beginning of December 2021 suggest the omicron variant. Therefore, molecular surveillance studies that are planned to take epidemiological data into consideration and to examine the prevalence and gene-based analysis of local and worldwide variants are required.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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