ABSTRACT Bacground/Aims: Hand trauma is common in emergency departments, with approximately 20% of regional traumas involving hand injuries. Extensor tendon lacerations, often caused by sharp objects, are frequently encountered but may be overlooked, leading to significant morbidity. This study aims to retrospectively review cases of extensor tendon lacerations in the upper extremities to highlight the importance of thorough evaluation and management in the emergency department. Methods: A single-center retrospective study included 114 patients presenting to the emergency department with extensor tendon lacerations. Data on patient demographics, injury characteristics, treatment, complications, and costs were collected and analyzed. Statistical analysis was performed using SPSS version 26.0. Results: The majority of patients were male adults, with sharp objects such as knives being the most common cause of injury. Extensor tendon repairs were predominantly performed in the emergency department, with complications observed in 14.9% of cases. The mean cost of treatment was $255.97. Factors influencing the decision to perform repair in the operating room included patient age, injury characteristics, and associated injuries. Conclusions: Extensor tendon lacerations in the upper extremities represent a significant burden in emergency departments. Our findings emphasize the importance of thorough evaluation and timely management to prevent missed diagnoses and optimize patient outcomes. Repairing extensor tendon injuries in the emergency department can be cost-effective and efficient, but careful consideration of patient and injury factors is necessary to determine the most appropriate treatment setting.
{"title":"Evaluation Of Clinical And Cost Analysis Of Patients Applying To The Emergency Service With Extensor Tendon Incision In The Upper Extremity","authors":"Mehmet Burak Yalçın, K. Şener","doi":"10.16899/jcm.1442209","DOIUrl":"https://doi.org/10.16899/jcm.1442209","url":null,"abstract":"ABSTRACT\u0000Bacground/Aims:\u0000Hand trauma is common in emergency departments, with approximately 20% of regional traumas involving hand injuries. Extensor tendon lacerations, often caused by sharp objects, are frequently encountered but may be overlooked, leading to significant morbidity. This study aims to retrospectively review cases of extensor tendon lacerations in the upper extremities to highlight the importance of thorough evaluation and management in the emergency department.\u0000Methods:\u0000A single-center retrospective study included 114 patients presenting to the emergency department with extensor tendon lacerations. Data on patient demographics, injury characteristics, treatment, complications, and costs were collected and analyzed. Statistical analysis was performed using SPSS version 26.0.\u0000Results:\u0000The majority of patients were male adults, with sharp objects such as knives being the most common cause of injury. Extensor tendon repairs were predominantly performed in the emergency department, with complications observed in 14.9% of cases. The mean cost of treatment was $255.97. Factors influencing the decision to perform repair in the operating room included patient age, injury characteristics, and associated injuries.\u0000Conclusions:\u0000Extensor tendon lacerations in the upper extremities represent a significant burden in emergency departments. Our findings emphasize the importance of thorough evaluation and timely management to prevent missed diagnoses and optimize patient outcomes. Repairing extensor tendon injuries in the emergency department can be cost-effective and efficient, but careful consideration of patient and injury factors is necessary to determine the most appropriate treatment setting.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140389368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: The proximity of the root tips of the maxillary posterior teeth to the maxillary sinus causes odontogenic infection to become a potential source of maxillary sinusitis. This study aims to evaluate the relationship between dental pathologies and maxillary sinus abnormalities using cone beam computed tomography (CBCT). Material and Method: In this study, 300 patients who applied to our clinic for any reason 600 maxillary sinus cone beam computed tomography images of the patient were analyzed retrospectively. Maxillary sinus diseases and dental pathologies categoized among themselves. Results: The age of all patients ranged between 18 and 77 years, with a mean age of 41.38 (±14.39) years. No pathology was detected in 359 (59.8%) of the maxillary sinuses examined which were considered healthy sinuses. The most common pathology in 241 (40.2%) of the maxillary sinuses in the imaging area was mucosal thickening (MT). A statistically significant relationship was detected between teeth with periapical lesions (PL) and MT (p<0.05). No statistically significant relationship was found between restorative applications, oro-antral fistula (OAF), periodontal bone loss (PBL), and maxillary sinusitis (MS) (p<0.05). Conclusion: Odontogenic infections and inflammatory events are the causes of maxillary sinus pathologies and may play a role in their formation. CBCT, maxillary posterior teeth and maxillary sinüs in demonstrating the relationship between and in the diagnosis of odontogenous sinus pathlogies is quite useful.
{"title":"Evaluation Of The Frequency, Localization And Relationship Of Maxillary Sinus Pathologies With Dental Pathologies By Cone Beam Computed Tomography (CBCT)","authors":"Emre Haylaz, Gediz Geduk, Çiğdem Şeker","doi":"10.16899/jcm.1438173","DOIUrl":"https://doi.org/10.16899/jcm.1438173","url":null,"abstract":"Background: The proximity of the root tips of the maxillary posterior teeth to the maxillary sinus causes odontogenic infection to become a potential source of maxillary sinusitis. This study aims to evaluate the relationship between dental pathologies and maxillary sinus abnormalities using cone beam computed tomography (CBCT).\u0000\u0000Material and Method: In this study, 300 patients who applied to our clinic for any reason 600 maxillary sinus cone beam computed tomography images of the patient were analyzed retrospectively. Maxillary sinus diseases and dental pathologies categoized among themselves.\u0000\u0000Results: The age of all patients ranged between 18 and 77 years, with a mean age of 41.38 (±14.39) years. No pathology was detected in 359 (59.8%) of the maxillary sinuses examined which were considered healthy sinuses. The most common pathology in 241 (40.2%) of the maxillary sinuses in the imaging area was mucosal thickening (MT). A statistically significant relationship was detected between teeth with periapical lesions (PL) and MT (p<0.05). No statistically significant relationship was found between restorative applications, oro-antral fistula (OAF), periodontal bone loss (PBL), and maxillary sinusitis (MS) (p<0.05).\u0000\u0000Conclusion: Odontogenic infections and inflammatory events are the causes of maxillary sinus pathologies and may play a role in their formation. CBCT, maxillary posterior teeth and maxillary sinüs in demonstrating the relationship between and in the diagnosis of odontogenous sinus pathlogies is quite useful.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140390496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/aims: Vitiligo is a severe skin disease that significantly affects individuals’ quality of life due to striking color changes in external appearance, and one that causes the majority of patients to feel stigmatized. This study was conducted to determine the effects of vitiligo on patients’ psychological and social lives and to elucidate how they perceive the disease. Methods: The research was conducted as an epidemiological study. The Dermatological Life Quality Index (DLQI) was applied to patients with vitiligo presenting to our clinic and to a control group. Results: Fifty patients with vitiligo and 50 healthy individuals were enrolled. The vitiligo group consisted of 26 (52%) women and 24 (48%) men, and the healthy control group of 24 (48%) women and 26 (52%) men. The patients’ mean age was 37.2 ± 13.1 years, and that of the healthy controls 34.7 ± 9.2 years. (p=0.2). No significant age or sex differences were observed between the patient and control groups (p=0.2 and p<0.05, respectively). The mean duration of the disease was 83.9 ± 72.9 months. The most common vitiligo subtype was focal vitiligo, at 52%. The vitiligo and control groups’ mean DLQI scores were 5.5 ± 5.0 and 1.4 ± 1.3, respectively, the difference being statistically significant (p<0.05) Conclusion: The findings of this study show that the quality of life of the patients with vitiligo was significantly impaired compared to the control group.
{"title":"A determination of the quality of life of patients with vitiligo using the dermatological life quality index","authors":"Erdal Pala, Mustafa Atasoy","doi":"10.16899/jcm.1431049","DOIUrl":"https://doi.org/10.16899/jcm.1431049","url":null,"abstract":"Background/aims: Vitiligo is a severe skin disease that significantly affects individuals’ quality of life due to striking color changes in external appearance, and one that causes the majority of patients to feel stigmatized. This study was conducted to determine the effects of vitiligo on patients’ psychological and social lives and to elucidate how they perceive the disease. \u0000Methods: The research was conducted as an epidemiological study. The Dermatological Life Quality Index (DLQI) was applied to patients with vitiligo presenting to our clinic and to a control group. \u0000Results: Fifty patients with vitiligo and 50 healthy individuals were enrolled. The vitiligo group consisted of 26 (52%) women and 24 (48%) men, and the healthy control group of 24 (48%) women and 26 (52%) men. The patients’ mean age was 37.2 ± 13.1 years, and that of the healthy controls 34.7 ± 9.2 years. (p=0.2). No significant age or sex differences were observed between the patient and control groups (p=0.2 and p<0.05, respectively). The mean duration of the disease was 83.9 ± 72.9 months. The most common vitiligo subtype was focal vitiligo, at 52%. The vitiligo and control groups’ mean DLQI scores were 5.5 ± 5.0 and 1.4 ± 1.3, respectively, the difference being statistically significant (p<0.05)\u0000Conclusion: The findings of this study show that the quality of life of the patients with vitiligo was significantly impaired compared to the control group.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140396917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: This study aimed to investigate the acute effect of kinesio taping applied to athletes and sedentary individuals on vertical and horizontal jumping performances. Methods: The study included 20 licensed male basketball players and 20 male sedentary individuals between the ages of 18-25. Vertical jump height and horizontal jump distance were evaluated. Free jumping and squat jumping tests were applied to measure the vertical jump height. Single leg hop test was chosen for the measurement of horizontal jump distance. Single leg hop test was performed with the dominant foot. Tests after kinesio taping were performed 10 minutes after facilitation technique was applied to gastrocnemius muscle. Results: A comparison of the pre- and post-taping data in the athlete group revealed a significant increase in both squat jump and single leg hop tests (p<0.05). In the sedentary group, there was a significant increase only in the single leg hop test compared to before taping (p<0.05). All pretest and posttest values of the athlete group were higher than the sedentary group (p>0.05). In terms of the performance increases after kinesio taping, the increases in the athlete group were higher for all tests compared to the sedentary group (p>0.05). Conclusions: Our study revealed that kinesio taping can improve jumping performance in both athletes and sedentary individuals. We think that kinesio taping could improve the performance especially in sports where jumping movements are frequently used such as basketball.
{"title":"Acute Effect of Kinesio Taping Applied to Gastrocnemius Muscle on Jumping Performance in Athletes and Sedentary Individuals","authors":"Kağan Üstün, Hilal Irmak Sapmaz, Sadık Buğrahan Şimşek","doi":"10.16899/jcm.1428083","DOIUrl":"https://doi.org/10.16899/jcm.1428083","url":null,"abstract":"Aim: This study aimed to investigate the acute effect of kinesio taping applied to athletes and sedentary individuals on vertical and horizontal jumping performances.\u0000Methods: The study included 20 licensed male basketball players and 20 male sedentary individuals between the ages of 18-25. Vertical jump height and horizontal jump distance were evaluated.\u0000Free jumping and squat jumping tests were applied to measure the vertical jump height. Single leg hop test was chosen for the measurement of horizontal jump distance. Single leg hop test was performed with the dominant foot. Tests after kinesio taping were performed 10 minutes after facilitation technique was applied to gastrocnemius muscle.\u0000Results: A comparison of the pre- and post-taping data in the athlete group revealed a significant increase in both squat jump and single leg hop tests (p<0.05). In the sedentary group, there was a significant increase only in the single leg hop test compared to before taping (p<0.05). All pretest and posttest values of the athlete group were higher than the sedentary group (p>0.05). In terms of the performance increases after kinesio taping, the increases in the athlete group were higher for all tests compared to the sedentary group (p>0.05).\u0000Conclusions: Our study revealed that kinesio taping can improve jumping performance in both athletes and sedentary individuals. We think that kinesio taping could improve the performance especially in sports where jumping movements are frequently used such as basketball.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140396779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ABSTRACT AIM: This study aims to assist the surgical treatment plan by increasing the rate of correct preoperative diagnoses through comparing the clinical, radiological, and laboratory findings of appendiceal mucocele (AM) and acute appendicitis (AA) before surgery. MATERIALS AND METHODS: The study included 63 patients with a histopathologic diagnosis of AM and AA among 4867 patients who underwent appendectomy with the diagnosis of acute appendicitis in the general surgery clinic between 2009 and 2020. The patients were separated into two groups: those with AM (21 patients) and those with AA (42 patients). Age, gender, physical examination (PE), Alvarado appendicitis score, ultrasonography (USG), computed tomography (CT), laboratory, preoperative diagnosis, intraoperative diagnosis, and pathological diagnosis results of both groups were compared. RESULTS: PE, abdominal pain, nausea, vomiting, fever symptoms, and Alvarado score were found to be significant between the two groups (p<0.05). In addition, WBC, NE, LYM %, and CRP were found to be high in group 2 (p<0.05), while there was no difference in radiological diagnosis (USG/CT) between the two groups (p<0.05). However, the appendix diameter was larger in group 1 (p<0.05). Patients with AM in 80% preoperatively, and 52% intraoperatively were operated on with a provisional diagnosis of AA. The second surgery was performed in Group 1 with a rate of 9.5% (2/21). CONCLUSION: In our study, patients with AM who underwent surgery with a diagnosis of AA were found to differ in radiological, clinical, and laboratory findings from patients with AA. KEYWORDS: Appendiceal Mucocele, Acute Appendicitis, Differential Diagnosis
ABSTRACTAIM: 本研究旨在通过比较阑尾粘液瘤（AM）和急性阑尾炎（AA）术前的临床、放射学和实验室检查结果，提高术前诊断的正确率，从而帮助制定手术治疗方案。这些患者被分为两组：AM 患者（21 人）和 AA 患者（42 人）。比较两组患者的年龄、性别、体格检查（PE）、阿尔瓦拉多阑尾炎评分、超声波检查（USG）、计算机断层扫描（CT）、实验室检查、术前诊断、术中诊断和病理诊断结果。结果：发现两组患者的 PE、腹痛、恶心、呕吐、发热症状和 Alvarado 评分差异显著（P<0.05）。此外，发现第 2 组的白细胞、NE、LYM % 和 CRP 偏高（P<0.05），而两组的放射诊断（USG/CT）无差异（P<0.05）。然而，第 1 组的阑尾直径更大（P<0.05）。80% 的 AM 患者术前诊断为 AA，52% 的患者术中临时诊断为 AA。第 1 组进行第二次手术的比例为 9.5%（2/21）。结论：在我们的研究中发现，在诊断为 AA 的情况下接受手术的 AM 患者与 AA 患者在放射学、临床和实验室检查结果上存在差异。关键词： 阑尾黏液囊 急性阑尾炎 鉴别诊断
{"title":"Apendiks mukoselini akut apandisitten ayırmada klinik, radyolojik ve laboratuvar belirteçlerin rolü","authors":"Hacı Bolat, Ali Erdoğan, Caner Özbey","doi":"10.16899/jcm.1406168","DOIUrl":"https://doi.org/10.16899/jcm.1406168","url":null,"abstract":"ABSTRACT\u0000AIM: This study aims to assist the surgical treatment plan by increasing the rate of correct preoperative diagnoses through comparing the clinical, radiological, and laboratory findings of appendiceal mucocele (AM) and acute appendicitis (AA) before surgery.\u0000MATERIALS AND METHODS: The study included 63 patients with a histopathologic diagnosis of AM and AA among 4867 patients who underwent appendectomy with the diagnosis of acute appendicitis in the general surgery clinic between 2009 and 2020. The patients were separated into two groups: those with AM (21 patients) and those with AA (42 patients). Age, gender, physical examination (PE), Alvarado appendicitis score, ultrasonography (USG), computed tomography (CT), laboratory, preoperative diagnosis, intraoperative diagnosis, and pathological diagnosis results of both groups were compared. \u0000\u0000RESULTS: PE, abdominal pain, nausea, vomiting, fever symptoms, and Alvarado score were found to be significant between the two groups (p<0.05). In addition, WBC, NE, LYM %, and CRP were found to be high in group 2 (p<0.05), while there was no difference in radiological diagnosis (USG/CT) between the two groups (p<0.05). However, the appendix diameter was larger in group 1 (p<0.05). Patients with AM in 80% preoperatively, and 52% intraoperatively were operated on with a provisional diagnosis of AA. The second surgery was performed in Group 1 with a rate of 9.5% (2/21). \u0000CONCLUSION: In our study, patients with AM who underwent surgery with a diagnosis of AA were found to differ in radiological, clinical, and laboratory findings from patients with AA. \u0000KEYWORDS: Appendiceal Mucocele, Acute Appendicitis, Differential Diagnosis","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140491887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
İdris Baydar, Ahmet Veli Şani̇baş, Doğan Nasır Binici
BACKGROUND/AIMS: Prediabetes is considered a risk factor for diabetes mellitus (DM) and cardiovascular diseases. Complications are also detected during diagnosis in 10-40% of diabetes patients. Diabetic nephropathy is one of the critical microvascular complications of diabetes. Studies have shown that prediabetes is associated with the development of glomerular hyperfiltration and albuminuria, as in the early stages of diabetes. Identifying patients before overt DM occurs is important for early diagnosis and treatment of nephropathy and DM. The aim of our study is to investigate the presence and frequency of nephropathy in prediabetes patients. METHODS: Patients who applied to the outpatient internal medicine and endocrinology outpatient clinics and whose random fasting blood sugar was ≥100 mg/dl were evaluated. Oral glucose tolerance test (OGTT) was performed and HbA1C values were measured. 280 patients diagnosed with prediabetes and evaluated for nephropathy were included in the study. RESULTS: Nephropathy was detected in 81 (28.9%) of the patients. The average HbA1C value of the group with nephropathy was 6.28% (sd: 0.52) and the average HbA1C value of the group without nephropathy was 6.05% (sd: 0.29). The average HbA1C value was found to be significantly higher in the group with nephropathy (p=0.000). CONCLUSIONS: The fact that nephropathy was detected in 28.9% of the patients showed once again the seriousness of prediabetes. Therefore, patients with prediabetes, especially those with higher HbA1C values, need to be evaluated more carefully in terms of nephropathy and CKD.
{"title":"Diyabet Aşikar Olmasa da Komplikasyonları Aşikar Olabilir, Prediyabet Hastalarında Nefropatinin Sıklığı","authors":"İdris Baydar, Ahmet Veli Şani̇baş, Doğan Nasır Binici","doi":"10.16899/jcm.1388853","DOIUrl":"https://doi.org/10.16899/jcm.1388853","url":null,"abstract":"BACKGROUND/AIMS: Prediabetes is considered a risk factor for diabetes mellitus (DM) and cardiovascular diseases. Complications are also detected during diagnosis in 10-40% of diabetes patients. Diabetic nephropathy is one of the critical microvascular complications of diabetes. Studies have shown that prediabetes is associated with the development of glomerular hyperfiltration and albuminuria, as in the early stages of diabetes. Identifying patients before overt DM occurs is important for early diagnosis and treatment of nephropathy and DM.\u0000The aim of our study is to investigate the presence and frequency of nephropathy in prediabetes patients.\u0000METHODS: Patients who applied to the outpatient internal medicine and endocrinology outpatient clinics and whose random fasting blood sugar was ≥100 mg/dl were evaluated. Oral glucose tolerance test (OGTT) was performed and HbA1C values were measured. 280 patients diagnosed with prediabetes and evaluated for nephropathy were included in the study.\u0000RESULTS: Nephropathy was detected in 81 (28.9%) of the patients. The average HbA1C value of the group with nephropathy was 6.28% (sd: 0.52) and the average HbA1C value of the group without nephropathy was 6.05% (sd: 0.29). The average HbA1C value was found to be significantly higher in the group with nephropathy (p=0.000).\u0000CONCLUSIONS: The fact that nephropathy was detected in 28.9% of the patients showed once again the seriousness of prediabetes. Therefore, patients with prediabetes, especially those with higher HbA1C values, need to be evaluated more carefully in terms of nephropathy and CKD.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140491262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dilek Tezcan, M. K. Körez, Selda Hakbi̇len, Mustafa Emin Kaygisiz, Semral Gülcemal, Sema Yi̇lmaz
Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease which influences the proportion of immune cells. Tumor necrosis factor alpha (TNF-α) is essential in the pathogenesis of AS, and TNF inhibitors are the most effective treatment for AS patients. In recent years, routine blood parameters were reported as markers of systemic inflammation associated with the diagnosis and prognosis of numerous malignancies and chronic inflammatory diseases. This study aimed to investigate the relationship between haematological parameters and clinical parameters, disease severity and treatment response in AS patients treated with TNF inhibitors. Methods: A total of 326 participants were recruited from the rheumatology department in this study. Participants were divided into healthy controls (n = 178) and AS (n = 148). Neutrophil, lymphocyte, monocyte and platelet counts, neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), platelet crit (PCT), mean platelet volume (MPV), red cell distribution width (RDW), systemic inflammatory index (SII), systemic inflammatory response index (SIRI), cluster systemic inflammation index (AISI) and RPR levels were analyzed for each participant. They were compared between healthy control, AS patients during the pre-treatment phase and three months after the treatment. Results: RDW, PLR, NLR, MLR, SIRI, AISI and SII were higher than healthy controls and decreased with treatment except SIRI. The decrease in AISI and SII after treatment was significant in HLA-B27 positive patients. MPV was lower than healthy controls and increased with treatment. SII, SIRI and AISI were significantly higher in the active AS patients than in the inactive patient. Also, they were correlated with erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). Conclusion: SII, AISI, and SIRI may be valuable markers for demonstrating disease activation and evaluating the effectiveness of anti‐TNF‐α therapy.
背景：强直性脊柱炎（AS）是一种影响免疫细胞比例的慢性炎症性疾病。肿瘤坏死因子α（TNF-α）在强直性脊柱炎的发病机制中起着至关重要的作用，TNF抑制剂是治疗强直性脊柱炎患者最有效的药物。近年来，有报道称血常规指标是全身炎症的标志物，与许多恶性肿瘤和慢性炎症性疾病的诊断和预后有关。本研究旨在探讨接受 TNF 抑制剂治疗的 AS 患者的血液学参数与临床参数、疾病严重程度和治疗反应之间的关系：方法：本研究从风湿病科招募了326名参与者。参与者分为健康对照组（n = 178）和强直性脊柱炎组（n = 148）。中性粒细胞、淋巴细胞、单核细胞和血小板计数、中性粒细胞-淋巴细胞比值（NLR）、单核细胞-淋巴细胞比值（MLR）、血小板-淋巴细胞比值（PLR）、血小板计数（PCT）、平均血小板体积（MPV）、红细胞分布宽度（RDW）、血小板计数（PCT）、平均血小板体积（MPV）、分析了每位受试者的红细胞分布宽度（RDW）、全身炎症指数（SII）、全身炎症反应指数（SIRI）、集群全身炎症指数（AISI）和 RPR 水平。结果：RDW、PLR、NLR、MLR、SIRI、AISI 和 SII 均高于健康对照组，除 SIRI 外，其他指标均随治疗而下降。治疗后，HLA-B27 阳性患者的 AISI 和 SII 下降明显。MPV 低于健康对照组，并随治疗而升高。活动期强直性脊柱炎患者的SII、SIRI和AISI明显高于非活动期患者。此外，它们还与红细胞沉降率（ESR）、C反应蛋白（CRP）和巴斯强直性脊柱炎疾病活动指数（BASDAI）相关：结论：SII、AISI 和 SIRI 可能是显示疾病激活和评估抗肿瘤坏死因子-α 治疗效果的重要标志物。
{"title":"ANKİLOZAN SPONDİLİT HASTALARINDA HASTALIK AKTİVİTESİ VE ANTİ-TÜMÖR NEKROZ FAKTÖRÜ ALFA AJANLAR İLE TEDAVİ YANITINI DEĞERLENDİRMEDE HEMATOLOJİK ENDEKSLERİN KLİNİK YARARLILIĞI","authors":"Dilek Tezcan, M. K. Körez, Selda Hakbi̇len, Mustafa Emin Kaygisiz, Semral Gülcemal, Sema Yi̇lmaz","doi":"10.16899/jcm.1415761","DOIUrl":"https://doi.org/10.16899/jcm.1415761","url":null,"abstract":"Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease which influences the proportion of immune cells. Tumor necrosis factor alpha (TNF-α) is essential in the pathogenesis of AS, and TNF inhibitors are the most effective treatment for AS patients. In recent years, routine blood parameters were reported as markers of systemic inflammation associated with the diagnosis and prognosis of numerous malignancies and chronic inflammatory diseases. This study aimed to investigate the relationship between haematological parameters and clinical parameters, disease severity and treatment response in AS patients treated with TNF inhibitors.\u0000Methods: A total of 326 participants were recruited from the rheumatology department in this study. Participants were divided into healthy controls (n = 178) and AS (n = 148). Neutrophil, lymphocyte, monocyte and platelet counts, neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), platelet crit (PCT), mean platelet volume (MPV), red cell distribution width (RDW), systemic inflammatory index (SII), systemic inflammatory response index (SIRI), cluster systemic inflammation index (AISI) and RPR levels were analyzed for each participant. They were compared between healthy control, AS patients during the pre-treatment phase and three months after the treatment.\u0000Results: RDW, PLR, NLR, MLR, SIRI, AISI and SII were higher than healthy controls and decreased with treatment except SIRI. The decrease in AISI and SII after treatment was significant in HLA-B27 positive patients. MPV was lower than healthy controls and increased with treatment. SII, SIRI and AISI were significantly higher in the active AS patients than in the inactive patient. Also, they were correlated with erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI).\u0000Conclusion: SII, AISI, and SIRI may be valuable markers for demonstrating disease activation and evaluating the effectiveness of anti‐TNF‐α therapy.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140492586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract: Aim: To investigate the effect of advancing age on postoperative outcomes in plastic surgery, focusing on patients aged 60 years and above. Methods: A retrospective analysis of clinic data from January 1, 2020, to October 1, 2023, was conducted. Data included patient demographics, preoperative comorbidities, surgical details, and 30-day postoperative complications. Logistic regression models were employed to evaluate the association between age and complication rates, adjusting for confounders like comorbidities and surgery types. Results: The study found a significant association between increasing age and higher complication rates within 30 days post-surgery. It also revealed that older surgeons tend to have lower complication rates. Additionally, factors like smoking, obesity, and gender were identified as influential in postoperative complications. Conclusions: Advancing age is independently associated with an increased risk of postoperative complications in plastic surgery. The study highlights the need for a comprehensive approach to evaluate postoperative outcomes, considering various patient and surgeon factors.
{"title":"Plastik Cerrahide Yaşın Ameliyat Sonrası Sonuçlara Etkisi: Veri Analizi ve Çıkarımlar","authors":"Abdulkadir Calavul","doi":"10.16899/jcm.1407776","DOIUrl":"https://doi.org/10.16899/jcm.1407776","url":null,"abstract":"Abstract:\u0000Aim: To investigate the effect of advancing age on postoperative outcomes in plastic surgery, focusing on patients aged 60 years and above.\u0000Methods: A retrospective analysis of clinic data from January 1, 2020, to October 1, 2023, was conducted. Data included patient demographics, preoperative comorbidities, surgical details, and 30-day postoperative complications. Logistic regression models were employed to evaluate the association between age and complication rates, adjusting for confounders like comorbidities and surgery types.\u0000Results: The study found a significant association between increasing age and higher complication rates within 30 days post-surgery. It also revealed that older surgeons tend to have lower complication rates. Additionally, factors like smoking, obesity, and gender were identified as influential in postoperative complications.\u0000Conclusions: Advancing age is independently associated with an increased risk of postoperative complications in plastic surgery. The study highlights the need for a comprehensive approach to evaluate postoperative outcomes, considering various patient and surgeon factors.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140503233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Background: Chest pain is a common disease in children. Chest pain is the second most common symptom referred to by paediatric cardiologists after cardiac murmurs. Objective: In this prospective study, we aimed to evaluate clinical characteristics and causes of chest pain in children admitted to our paediatric cardiology outpatient clinics. Methods: We conducted this prospective study among 446 patients with chest pain in a tertiary care hospital from 1 June 2017 to 1 June 2020. The demographic data and clinical characteristics of the patients were analysed. All patients were evaluated with a medical history, physical examination, laboratory tests, electrocardiogram and echocardiogram and if necessary telecardiogram, 24-hour electrocardiogram monitoring, exercise stress test and psychological evaluation were made. Results: The ratio of admissions with acute pain was 4% when 20% of the patients had chronic chest pain. The most common symptoms associated with chest pain were shortness of breath and palpitations. The non-cardiac causes were as follows: 25% musculoskeletal, 14% psychological, 9% respiratory, and 7% gastrointestinal, respectively. We found cardiac chest pain in 49 (11%) of patients. Idiopathic chest pain was found in 153 (34%) patients. Conclusions: Our study showed that the aetiology of chest pain in children and adolescents admitted with chest pain is mostly due to non-cardiac causes. We found the slightly frequency of elevated rate for cardiac aetiologies of paediatric chest pain compared to the literature. We suggest that in addition to anamnesis and careful examination, further investigation, if necessary, is important in determining the aetiology of chest pain.
{"title":"Clinical characteristics of children and adolescents admitted with chest pain","authors":"Gülden Ünver, A. Sert","doi":"10.16899/jcm.1295809","DOIUrl":"https://doi.org/10.16899/jcm.1295809","url":null,"abstract":"Abstract\u0000\u0000Background: Chest pain is a common disease in children. Chest pain is the second most common symptom referred to by paediatric cardiologists after cardiac murmurs.\u0000Objective: In this prospective study, we aimed to evaluate clinical characteristics and causes of chest pain in children admitted to our paediatric cardiology outpatient clinics.\u0000Methods: We conducted this prospective study among 446 patients with chest pain in a tertiary care hospital from 1 June 2017 to 1 June 2020. The demographic data and clinical characteristics of the patients were analysed. All patients were evaluated with a medical history, physical examination, laboratory tests, electrocardiogram and echocardiogram and if necessary telecardiogram, 24-hour electrocardiogram monitoring, exercise stress test and psychological evaluation were made.\u0000Results: The ratio of admissions with acute pain was 4% when 20% of the patients had chronic chest pain. The most common symptoms associated with chest pain were shortness of breath and palpitations. The non-cardiac causes were as follows: 25% musculoskeletal, 14% psychological, 9% respiratory, and 7% gastrointestinal, respectively. We found cardiac chest pain in 49 (11%) of patients. Idiopathic chest pain was found in 153 (34%) patients. \u0000Conclusions: Our study showed that the aetiology of chest pain in children and adolescents admitted with chest pain is mostly due to non-cardiac causes. We found the slightly frequency of elevated rate for cardiac aetiologies of paediatric chest pain compared to the literature. We suggest that in addition to anamnesis and careful examination, further investigation, if necessary, is important in determining the aetiology of chest pain.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140512513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Kalsifik Tendinit Tedavisinde Ultrason Eşliğinde Barbotaj","authors":"Baran Tuncer, Onur Kara, Ayşe Merve Ata","doi":"10.16899/jcm.1400997","DOIUrl":"https://doi.org/10.16899/jcm.1400997","url":null,"abstract":"Not applicable for Letter to the Editor.............................................................................................","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140512809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：