Mustafa Cüneyt ÇİÇEK, Mustafa DAĞLI, A Nihat BAYSAL, Emin BARBARUS, Hayat GÖKMENGİL, Hüseyin DURMAZ, İlyas Selim YILMAZ, Yalçın GÜNERHAN, Kadir DURGUT
Aim: The importance of endovascular procedures in the diagnosis and treatment of peripheral vascular diseases has seen a notable rise in recent years. Nevertheless, this surge has resulted in a corresponding rise in iatrogenic vascular complications and subsequent interventions associated with peripheral endovascular procedures. This study involved a retrospective evaluation of acute complications associated with endovascular treatments performed for lower limb peripheral artery diseases, as well as a closer look of the related therapeutic strategies for these challenges.
Materials and Methods: A retrospective evaluation was conducted on a cohort of 400 patients who received endovascular intervention for lower extremity peripheral artery disease at our clinic. The study included 27 patients (6.7%) from this cohort who received surgical or endovascular treatment for acute complications following endovascular intervention. Our preference for endovascular or surgical treatments was chosen based on the type and localization of the complications.
Results: The mean age of patients who experienced complications was 63.7±6 years. The complications were as follows in order of frequency: dissection 14 (51.9%) patients, arterial perforation 5 (18.5%) patients, major hematoma 3 (11.1%) patients, pseudoaneurysm 2 (7.4%) patients, distal embolism 2 (7.4%) patients and arterio-venous fistula 1 (3.7%) patient. In the treatment of complications, endovascular methods were preferred in 19 (4.7%) patients and surgical approaches were used in 8 (2%) patients. Following endovascular intervention, minor amputation was performed in one patient.
Conclusion: The rapid and effective management of complications related to peripheral endovascular procedures in the lower extremities is of utmost importance. Despite the notable advancements in endovascular procedures in recent years, there are scenarios where these interventions may be insufficient for dealing with complications. The management of such problems may necessitate surgical intervention. Hence, the integration of well-established and validated vascular surgical techniques with endovascular interventions is believed to yield optimal outcomes.
{"title":"Alt Ekstremite Periferik Arter Hastalığında Endovasküler Girişimlerden Kaynaklanan Akut Komplikasyonların Cerrahi Yönetimi: Eskimeyen Yeni","authors":"Mustafa Cüneyt ÇİÇEK, Mustafa DAĞLI, A Nihat BAYSAL, Emin BARBARUS, Hayat GÖKMENGİL, Hüseyin DURMAZ, İlyas Selim YILMAZ, Yalçın GÜNERHAN, Kadir DURGUT","doi":"10.16899/jcm.1348296","DOIUrl":"https://doi.org/10.16899/jcm.1348296","url":null,"abstract":"Aim: The importance of endovascular procedures in the diagnosis and treatment of peripheral vascular diseases has seen a notable rise in recent years. Nevertheless, this surge has resulted in a corresponding rise in iatrogenic vascular complications and subsequent interventions associated with peripheral endovascular procedures. This study involved a retrospective evaluation of acute complications associated with endovascular treatments performed for lower limb peripheral artery diseases, as well as a closer look of the related therapeutic strategies for these challenges.
 Materials and Methods: A retrospective evaluation was conducted on a cohort of 400 patients who received endovascular intervention for lower extremity peripheral artery disease at our clinic. The study included 27 patients (6.7%) from this cohort who received surgical or endovascular treatment for acute complications following endovascular intervention. Our preference for endovascular or surgical treatments was chosen based on the type and localization of the complications.
 Results: The mean age of patients who experienced complications was 63.7±6 years. The complications were as follows in order of frequency: dissection 14 (51.9%) patients, arterial perforation 5 (18.5%) patients, major hematoma 3 (11.1%) patients, pseudoaneurysm 2 (7.4%) patients, distal embolism 2 (7.4%) patients and arterio-venous fistula 1 (3.7%) patient. In the treatment of complications, endovascular methods were preferred in 19 (4.7%) patients and surgical approaches were used in 8 (2%) patients. Following endovascular intervention, minor amputation was performed in one patient.
 Conclusion: The rapid and effective management of complications related to peripheral endovascular procedures in the lower extremities is of utmost importance. Despite the notable advancements in endovascular procedures in recent years, there are scenarios where these interventions may be insufficient for dealing with complications. The management of such problems may necessitate surgical intervention. Hence, the integration of well-established and validated vascular surgical techniques with endovascular interventions is believed to yield optimal outcomes.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Percutaneous endoscopic gastrostomy (PEG) is a feeding method used in patients who are expected to require enteral nutrition for more than 2-3 weeks. We aimed to evaluate PEG indications, complications, and post-procedural patient prognosis in patients followed up in our intensive care unit and fed via PEG.
Materials and Methods: We retrospectively reviewed 51 patients receiving PEG between January 1, 2017, and December 31, 2022, in the Respiratory Intensive Care Unit.
Results: Among the patients receiving PEG, 30 (58%) were male. The average age was 63.9, ranging from 23 to 90. The mean scores for the Glasgow Coma Scale (GCS), Acute Physiology and Chronic Health Evaluation II (APACHE II), and Sepsis Related Organ Failure Assessment (SOFA) were 8.47, 22, and 7.45, respectively. The mean duration until PEG placement was 24.8 days, and the average intensive care unit (ICU) hospitalization was 48.8 days.PEG was performed in 21 patients (41.2%) due to cerebrovascular disease, in 19 patients (37.3%) due to Alzheimer, dementia, or Parkinson's disease, and 18 patients (35.3%) due to prolonged mechanical ventilation. The complication rate associated with PEG was 13.7%. Among the patients who underwent PEG, 35 (68.6%) were discharged, while 16 (31.4%) died.
Conclusion: Considering its easy use at bedside, low complication, and mortality rates, PEG insertion is appropriate for continuing enteral therapies, especially in intensive care patients with insufficient oral intake.
{"title":"Solunum Yoğun Bakım Ünitesinde Perkütan Endoskopik Gastrostominin Klinik Sonuçları","authors":"Kamuran ULUÇ, Esra AKKÜTÜK ÖNGEL, Nazan KÖYLÜ İLKAYA, Özkan DEVRAN, Ernur AY, Hatice KUTBAY ÖZÇELİK","doi":"10.16899/jcm.1331937","DOIUrl":"https://doi.org/10.16899/jcm.1331937","url":null,"abstract":"Aim: Percutaneous endoscopic gastrostomy (PEG) is a feeding method used in patients who are expected to require enteral nutrition for more than 2-3 weeks. We aimed to evaluate PEG indications, complications, and post-procedural patient prognosis in patients followed up in our intensive care unit and fed via PEG.
 Materials and Methods: We retrospectively reviewed 51 patients receiving PEG between January 1, 2017, and December 31, 2022, in the Respiratory Intensive Care Unit.
 Results: Among the patients receiving PEG, 30 (58%) were male. The average age was 63.9, ranging from 23 to 90. The mean scores for the Glasgow Coma Scale (GCS), Acute Physiology and Chronic Health Evaluation II (APACHE II), and Sepsis Related Organ Failure Assessment (SOFA) were 8.47, 22, and 7.45, respectively. The mean duration until PEG placement was 24.8 days, and the average intensive care unit (ICU) hospitalization was 48.8 days.PEG was performed in 21 patients (41.2%) due to cerebrovascular disease, in 19 patients (37.3%) due to Alzheimer, dementia, or Parkinson's disease, and 18 patients (35.3%) due to prolonged mechanical ventilation. The complication rate associated with PEG was 13.7%. Among the patients who underwent PEG, 35 (68.6%) were discharged, while 16 (31.4%) died.
 Conclusion: Considering its easy use at bedside, low complication, and mortality rates, PEG insertion is appropriate for continuing enteral therapies, especially in intensive care patients with insufficient oral intake.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Aims: Optic pathway gliomas (OPGs) are low-grade gliomas histologically represented by pilocytic astrocytoma (PA) in 90% of cases, can develop from any part of the visual pathways such as optic nerve, chiasm, optic tract, or optic radiations which frequently involve the hypothalamus. OPGs account for 3–5% of childhood central nervous system (CNS) tumors and about 2% of pediatric glial lesions. OPGs are believed to be the most prevalent intracranial tumor in patients with neurofibromatosis type 1 (NF-1) and can occur in 15–20% of NF-1 cases. The aim of this study is to evaluate the clinical features and treatment response in patients diagnosed with optic glioma and NF-1.
Methods: All cases diagnosed with OPG and received treatment in the Pediatric Oncology Department, between January 2015 to January 2021 were retrospectively evaluated. Inclusion criteria include children and adolescents with OPG aged between 0 and 18 years. The medical records (gender, age, tumor entity, tumor location) of patients, as well as their treatment history and magnetic resonance imaging (MRI) scans, were examined. The diagnosis of OPG was made clinically and radiologically by the tumor board. The recommendations of the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group were used in the diagnosis and evaluation of treatment response. Patients received intravenous chemotherapy with SIOP LGG 2004 (vincristine- carboplatin) with or without bevacizumab (10 mg/kg, started every 2 weeks), therapy or vinblastine (3 mg/m2, weekly).
Results: This study included 27 cases during the study period from January 2015 to January 2021. In this study there were 14 male (51.8 %) and 13 female (48.1 %) patients. The median age was 4.8 (range: 0.5–14.9) years. Biopsy was performed in three patients and the diagnosis was low-grade glioma (pilocytic astrocytoma) for all of them. Chemotherapy was administered to 22 cases in total. Twelve patients received vincristine-carboplatine, 5 patients received vincristine-carboplatin with bevacizumab and 5 patients received vinorelbine. Radiological response was evaluated in all 22 patients at 3 months MRI. No patient had a radiological complete respons, 11 patients (50%) had partial response, 2 patients (9%) presented with a progressive disease, showing an increase in measurements of 35% and 9 patients(40.9%) had stable disease at the 3-month evaluation.
Conclusions: Systemic and visual problems play a significant role in the selection of treatment for pediatric patients with optic gliomas. An essential treatment option for improving symptoms and reducing tumor size is systemic chemotherapy. A crucial therapy option for enhancing vision is bevacizumab for the patients with NF-associated OPG.
{"title":"Evaluation of Neurofibromatosis Type 1 Associated Optic Pathway Gliomas","authors":"Özge VURAL, Arzu OKUR, Faruk Güçlü PINARLI","doi":"10.16899/jcm.1350153","DOIUrl":"https://doi.org/10.16899/jcm.1350153","url":null,"abstract":"Background/Aims: Optic pathway gliomas (OPGs) are low-grade gliomas histologically represented by pilocytic astrocytoma (PA) in 90% of cases, can develop from any part of the visual pathways such as optic nerve, chiasm, optic tract, or optic radiations which frequently involve the hypothalamus. OPGs account for 3–5% of childhood central nervous system (CNS) tumors and about 2% of pediatric glial lesions. OPGs are believed to be the most prevalent intracranial tumor in patients with neurofibromatosis type 1 (NF-1) and can occur in 15–20% of NF-1 cases. The aim of this study is to evaluate the clinical features and treatment response in patients diagnosed with optic glioma and NF-1.
 Methods: All cases diagnosed with OPG and received treatment in the Pediatric Oncology Department, between January 2015 to January 2021 were retrospectively evaluated. Inclusion criteria include children and adolescents with OPG aged between 0 and 18 years. The medical records (gender, age, tumor entity, tumor location) of patients, as well as their treatment history and magnetic resonance imaging (MRI) scans, were examined. The diagnosis of OPG was made clinically and radiologically by the tumor board. The recommendations of the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group were used in the diagnosis and evaluation of treatment response. Patients received intravenous chemotherapy with SIOP LGG 2004 (vincristine- carboplatin) with or without bevacizumab (10 mg/kg, started every 2 weeks), therapy or vinblastine (3 mg/m2, weekly). 
 Results: This study included 27 cases during the study period from January 2015 to January 2021. In this study there were 14 male (51.8 %) and 13 female (48.1 %) patients. The median age was 4.8 (range: 0.5–14.9) years. Biopsy was performed in three patients and the diagnosis was low-grade glioma (pilocytic astrocytoma) for all of them. Chemotherapy was administered to 22 cases in total. Twelve patients received vincristine-carboplatine, 5 patients received vincristine-carboplatin with bevacizumab and 5 patients received vinorelbine. Radiological response was evaluated in all 22 patients at 3 months MRI. No patient had a radiological complete respons, 11 patients (50%) had partial response, 2 patients (9%) presented with a progressive disease, showing an increase in measurements of 35% and 9 patients(40.9%) had stable disease at the 3-month evaluation.
 Conclusions: Systemic and visual problems play a significant role in the selection of treatment for pediatric patients with optic gliomas. An essential treatment option for improving symptoms and reducing tumor size is systemic chemotherapy. A crucial therapy option for enhancing vision is bevacizumab for the patients with NF-associated OPG.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Fluopyram is a mitochondrial complex II inhibitor with low water solubility and a relatively long half-life in soil. So it may also be dangerous for humans. The effect of fluopyram on DNA damage was evaluated in human lymphocytes using the comet assay.
Materials and Methods: Lymphocytes of eight volunteers were isolated using histopaque-1077. Fluopyram was administered at doses of 0.05, 0.25, and 1.00 mg/mL for 1, 2, and 4 h. The comet assay was applied, and photographs of the slides were taken under a fluorescence microscope. 50 cells per slide were analyzed using the OpenComet software. The obtained results were statistically evaluated using one-way ANOVA.
Results: Fluopyram treatments at 1.00 mg/mL for 1 h and 0.05, 0.25, and 1.00 mg/mL for 2 and 4 h resulted in a statistically significant increase in DNA damage compared to the internal control groups (p
{"title":"Assessment of DNA Damage Induced by Velum® Prime in Human Lymphocytes","authors":"Vehbi Atahan TOĞAY, Dilek AŞCI ÇELİK","doi":"10.16899/jcm.1345215","DOIUrl":"https://doi.org/10.16899/jcm.1345215","url":null,"abstract":"Aim: Fluopyram is a mitochondrial complex II inhibitor with low water solubility and a relatively long half-life in soil. So it may also be dangerous for humans. The effect of fluopyram on DNA damage was evaluated in human lymphocytes using the comet assay.
 Materials and Methods: Lymphocytes of eight volunteers were isolated using histopaque-1077. Fluopyram was administered at doses of 0.05, 0.25, and 1.00 mg/mL for 1, 2, and 4 h. The comet assay was applied, and photographs of the slides were taken under a fluorescence microscope. 50 cells per slide were analyzed using the OpenComet software. The obtained results were statistically evaluated using one-way ANOVA.
 Results: Fluopyram treatments at 1.00 mg/mL for 1 h and 0.05, 0.25, and 1.00 mg/mL for 2 and 4 h resulted in a statistically significant increase in DNA damage compared to the internal control groups (p","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
İntroduction: Our research aimed to assess Acanthamoeba keratitis research trends and compare contributions from various nations, institutions, journals, and authors.
Methodology: A bibliometric design was used. We used the Web of Science database to extract all Acanthamoeba keratitis articles from 1970 to 2021. To collect publishing data, analyze publication trends, and visualize relevant data, Microsoft Excel and VOSviewer were used.
Results: 171 (31.784 %) of them were published as open Access. 92.751% of them were published in Science Citation Index Expanded indexed journals. The mean number of citations was 13733, with a median of 25.53, and the H index was 63. 77.32 % of the articles were published since 2000. University of Texas in the United States had the highest number of publications (78, 14.499%), followed by the University of London in the UK (63,11.71%). The United States (USA) ranked first in the number of publications (151, 28.067%), followed by the United Kingdom (49, 9.108%) and Germany (31, 5.762%). Publications from the USA were cited 6,344 times (42.01/median per publication), while publications from the UK were cited 2,949 times (60.18/median per publication). Acanthamoeba keratitis research has increased significantly in the last 15 years.
Conclusions: With the use of information visualization analysis, we were able to gain a wide understanding of the state of affairs, recognize trends, and identify hotspots. It is a more effective way to learn the literature and could give future researchers summarized data
{"title":"Acanthamoeba keratiti ile ilgili bilimsel literatürün bibliyometrik analiz","authors":"Oğuz EVLİCE, Burcu YÜCEKUL","doi":"10.16899/jcm.1342910","DOIUrl":"https://doi.org/10.16899/jcm.1342910","url":null,"abstract":"İntroduction: Our research aimed to assess Acanthamoeba keratitis research trends and compare contributions from various nations, institutions, journals, and authors. 
 
 Methodology: A bibliometric design was used. We used the Web of Science database to extract all Acanthamoeba keratitis articles from 1970 to 2021. To collect publishing data, analyze publication trends, and visualize relevant data, Microsoft Excel and VOSviewer were used. 
 
 Results: 171 (31.784 %) of them were published as open Access. 92.751% of them were published in Science Citation Index Expanded indexed journals. The mean number of citations was 13733, with a median of 25.53, and the H index was 63. 77.32 % of the articles were published since 2000. University of Texas in the United States had the highest number of publications (78, 14.499%), followed by the University of London in the UK (63,11.71%). The United States (USA) ranked first in the number of publications (151, 28.067%), followed by the United Kingdom (49, 9.108%) and Germany (31, 5.762%). Publications from the USA were cited 6,344 times (42.01/median per publication), while publications from the UK were cited 2,949 times (60.18/median per publication). Acanthamoeba keratitis research has increased significantly in the last 15 years. 
 
 Conclusions: With the use of information visualization analysis, we were able to gain a wide understanding of the state of affairs, recognize trends, and identify hotspots. It is a more effective way to learn the literature and could give future researchers summarized data","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: The aim of this study was to examine the effect of administrative meetings with family health center staff on cancer and autism screenings in a district of Istanbul.
Material and Method: The study was designed as an intervention research conducted in a district of Istanbul. The population of the study consisted of employees working in family health centers (24 family health centers) in Sultanbeyli district. The meetings were held at the end of February 2022 at the District Health Directorate building. During the meetings, the aspects that need to be improved, especially regarding cancer and autism screenings, were conveyed. Following these meetings for field staff, the changes in preventive health services (number of screenings) at the district level were analyzed. All data were analyzed retrospectively from district health directorate records.
Results: For cervical cancer screening, the total number of screenings in Sultanbeyli district in January-February and March-April were 144 and 235, respectively. For colon cancer, the total number of screenings in January-February and March-April were 54 and 277, respectively. The total number of autism screenings in January-February and March-April were 565 and 1388, respectively. Cervical cancer screenings, colon cancer screenings and autism screenings showed statistically significant increases after the meetings (p=0.002, p
目的:本研究的目的是检查伊斯坦布尔一个地区与家庭保健中心工作人员举行行政会议对癌症和自闭症筛查的影响。材料与方法:本研究设计为在伊斯坦布尔某地区进行的干预研究。研究对象包括在Sultanbeyli区家庭保健中心(24个家庭保健中心)工作的雇员。会议于2022年2月底在区卫生局大楼举行。在会议期间，双方传达了需要改进的方面，特别是关于癌症和自闭症筛查的方面。在这些外地工作人员会议之后，分析了地区一级预防性保健服务(检查次数)的变化。所有数据回顾性分析来自区卫生局的记录。
结果:苏丹贝利区1 - 2月和3 - 4月宫颈癌筛查总数分别为144例和235例。对于结肠癌，1月至2月和3月至4月的筛查总数分别为54例和277例。1月至2月和3月至4月的自闭症筛查总数分别为565例和1388例。宫颈癌筛查、结肠癌筛查和自闭症筛查在会议后显示有统计学意义的增加(p=0.002, p
{"title":"The Role of Communication with the Field during the Pandemic Period: A District Intervention Example in Preventive Health Services","authors":"Mehmet Akif SEZEROL, Zeynep Meva ALTAŞ","doi":"10.16899/jcm.1338980","DOIUrl":"https://doi.org/10.16899/jcm.1338980","url":null,"abstract":"Aim: The aim of this study was to examine the effect of administrative meetings with family health center staff on cancer and autism screenings in a district of Istanbul.
 Material and Method: The study was designed as an intervention research conducted in a district of Istanbul. The population of the study consisted of employees working in family health centers (24 family health centers) in Sultanbeyli district. The meetings were held at the end of February 2022 at the District Health Directorate building. During the meetings, the aspects that need to be improved, especially regarding cancer and autism screenings, were conveyed. Following these meetings for field staff, the changes in preventive health services (number of screenings) at the district level were analyzed. All data were analyzed retrospectively from district health directorate records.
 Results: For cervical cancer screening, the total number of screenings in Sultanbeyli district in January-February and March-April were 144 and 235, respectively. For colon cancer, the total number of screenings in January-February and March-April were 54 and 277, respectively. The total number of autism screenings in January-February and March-April were 565 and 1388, respectively. Cervical cancer screenings, colon cancer screenings and autism screenings showed statistically significant increases after the meetings (p=0.002, p","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background/Aims: The global prevalence of breast cancer continues to rise, necessitating heightened awareness, early detection, and effective management strategies. This study aimed to assess differences in breast cancer awareness, risk factors, symptoms, and attitudes among economically well-off female patients in Turkey.
Material and Methods: A single-center survey was conducted at a private hospital, involving 189 economically well-off patients. Descriptive statistics, Chi-square tests, ANOVA, and Kruskal-Wallis tests were used for data analysis.
Results: Participants had a mean age of 50.2 years, with the highest awareness of risk factors and symptoms observed in the 31-50 age group. Marital status and education were associated with breast cancer awareness, risk factors, symptoms, and screening methods. Education level correlated with enhanced knowledge of risk factors and symptoms. The prevalence of breast cancer risk awareness was 41.2%, with the most recognized risk factors being smoking and family history. Palpable lump (36.4%) and redness of breast skin (16.9%) were identified as common symptoms. Screening methods included self-breast examination (12.2%), physician examination (13.2%), ultrasonography (19%), magnetic resonance imaging (15.9%), and mammography (23.3%).
Discussion: Breast cancer remains a critical global health concern, necessitating increased awareness and early detection. In Turkey, breast cancer poses a significant health burden. Socioeconomic factors impact awareness and outcomes, with education and marital status influencing awareness levels. The study highlights the need for tailored interventions and accessible screening programs to enhance awareness and early detection.
Conclusion: This study sheds light on breast cancer awareness and attitudes among economically well-off female patients in Turkey. Education, marital status, and age play pivotal roles in shaping awareness levels. Targeted interventions and education are crucial for improving early detection, reducing mortality rates, and effectively addressing breast cancer.
{"title":"Özel Bir Hastanenin Kadın Hastaları Arasında Meme Kanseri Farkındalığı: Türkiye'de Risk Faktörleri, Semptomlar ve Tutumlar Üzerine Kesitsel Bir Çalışma","authors":"Hatice KAYIKÇIOĞLU","doi":"10.16899/jcm.1349391","DOIUrl":"https://doi.org/10.16899/jcm.1349391","url":null,"abstract":"Background/Aims: The global prevalence of breast cancer continues to rise, necessitating heightened awareness, early detection, and effective management strategies. This study aimed to assess differences in breast cancer awareness, risk factors, symptoms, and attitudes among economically well-off female patients in Turkey.
 Material and Methods: A single-center survey was conducted at a private hospital, involving 189 economically well-off patients. Descriptive statistics, Chi-square tests, ANOVA, and Kruskal-Wallis tests were used for data analysis.
 Results: Participants had a mean age of 50.2 years, with the highest awareness of risk factors and symptoms observed in the 31-50 age group. Marital status and education were associated with breast cancer awareness, risk factors, symptoms, and screening methods. Education level correlated with enhanced knowledge of risk factors and symptoms. The prevalence of breast cancer risk awareness was 41.2%, with the most recognized risk factors being smoking and family history. Palpable lump (36.4%) and redness of breast skin (16.9%) were identified as common symptoms. Screening methods included self-breast examination (12.2%), physician examination (13.2%), ultrasonography (19%), magnetic resonance imaging (15.9%), and mammography (23.3%).
 Discussion: Breast cancer remains a critical global health concern, necessitating increased awareness and early detection. In Turkey, breast cancer poses a significant health burden. Socioeconomic factors impact awareness and outcomes, with education and marital status influencing awareness levels. The study highlights the need for tailored interventions and accessible screening programs to enhance awareness and early detection.
 Conclusion: This study sheds light on breast cancer awareness and attitudes among economically well-off female patients in Turkey. Education, marital status, and age play pivotal roles in shaping awareness levels. Targeted interventions and education are crucial for improving early detection, reducing mortality rates, and effectively addressing breast cancer.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ela DELİKGÖZ SOYKUT, Eylem ODABASİ, Serdar ŞENOL, Salih Buğra YILMAZ, Hatice TATAROĞLU, Ahmet BARAN
Aim: Gastrointestinal cancers rarely metastasize to the brain and constitute 4-8% of all brain metastases (BM). Survival is generally poor for BM from gastrointestinal cancers and stereotactic radiosurgery (SRS) is frequently used in its management. Since the data are still insufficient due to their rare presentation, we aim to analyze the clinical results of patients who underwent SRS for BM due to gastrointestinal cancers.
Material and Method: We retrospectively reviewed patients with BM from gastrointestinal cancers who received robotic SRS with CyberKnife at our institute from October 2013 to December 2022. Clinical characteristics and treatment outcomes were recorded. Study endpoints were local control rates, distant brain control rates, and overall survival (OS).
Results: A total of 61 BM were detected in 42 patients. The median clinical follow-up time was 7 (0.5-36) months. Nine lesions progressed in the irradiated area, 14 new lesions were observed outside the irradiated area. The local control rate was 85.1% and the distant brain control rate was 77%. The median OS was 8 months; 12-month and 24-month OS were 31.6% and 10.5%, respectively. Patients with high performance status had better OS (p=0.016). The prognostic scoring scales RPA and GI-GPA were both associated with OS (p=0.049, p=0.002). Multivariate analysis found a significant association between GI-GPA classes and OS (p=0.011).
Conclusion: We obtained comparable results in terms of local control, distant brain control and OS in this challenging patient population. The use of GI-GPA prognostic scoring scales in routine practice will guide the selection of the most appropriate patient for SRS.
{"title":"Gastrointestinal Kanserlerden Gelişen Beyin Metastazı Olan Hastalarda Stereotaktik Radyocerrahiye Yanıtın ve Sağkalım Sonuçlarının Değerlendirilmesi","authors":"Ela DELİKGÖZ SOYKUT, Eylem ODABASİ, Serdar ŞENOL, Salih Buğra YILMAZ, Hatice TATAROĞLU, Ahmet BARAN","doi":"10.16899/jcm.1351577","DOIUrl":"https://doi.org/10.16899/jcm.1351577","url":null,"abstract":"Aim: Gastrointestinal cancers rarely metastasize to the brain and constitute 4-8% of all brain metastases (BM). Survival is generally poor for BM from gastrointestinal cancers and stereotactic radiosurgery (SRS) is frequently used in its management. Since the data are still insufficient due to their rare presentation, we aim to analyze the clinical results of patients who underwent SRS for BM due to gastrointestinal cancers.
 Material and Method: We retrospectively reviewed patients with BM from gastrointestinal cancers who received robotic SRS with CyberKnife at our institute from October 2013 to December 2022. Clinical characteristics and treatment outcomes were recorded. Study endpoints were local control rates, distant brain control rates, and overall survival (OS).
 Results: A total of 61 BM were detected in 42 patients. The median clinical follow-up time was 7 (0.5-36) months. Nine lesions progressed in the irradiated area, 14 new lesions were observed outside the irradiated area. The local control rate was 85.1% and the distant brain control rate was 77%. The median OS was 8 months; 12-month and 24-month OS were 31.6% and 10.5%, respectively. Patients with high performance status had better OS (p=0.016). The prognostic scoring scales RPA and GI-GPA were both associated with OS (p=0.049, p=0.002). Multivariate analysis found a significant association between GI-GPA classes and OS (p=0.011). 
 Conclusion: We obtained comparable results in terms of local control, distant brain control and OS in this challenging patient population. The use of GI-GPA prognostic scoring scales in routine practice will guide the selection of the most appropriate patient for SRS.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136342847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: This study aims to show seasonal differences by analysing the chest disease consultations requested by an emergency unit in summer (June, July, and August) and winter (December, January, and February) months.
Methods: Patients over the age of 18 years who were directed by an emergency unit to the Department of Chest Diseases between 1 December 2021 and 31 August 2022 and whose thoracic computerized tomography results were available were included in the study. Variables such as the patients’ demographic characteristics, complaints, results of the examinations done in the emergency unit, hospitalization rates, place of hospitalization (hospital ward or intensive care), and pre-diagnosis before hospitalization were evaluated. The statistical significance level was accepted as p < 0.05 in all calculations and statistical analysis of the data was conducted using IBM SPSS Statistics 26 (IBM Corp., Armonk, NY, USA).
Results: For the 409 patients included in this study, more consultations were requested in the winter months (n = 239, 58.4%). We identified significant differences between the seasonal groups in terms of the complaints and the additional radiological imaging findings of patients consulted in summer and winter months (p < 0.05). The most common complaint in both seasons was shortness of breath. Pleural effusion was less common among the additional radiological findings of both seasons.
Conclusion: This study has revealed significant differences between seasonal groups in terms of complaints and additional radiological imaging findings of patients with consultations in summer and winter months. However, there were no significant differences between the seasonal groups in terms of age, sex, pre-diagnosis, place of hospitalization, or main radiological findings.
{"title":"Analysis of Chest Disease Consultations Requested by an Emergency Unit in Summer and Winter Months","authors":"Gökhan ÇORAPLI, Ercan ÇİL","doi":"10.16899/jcm.1283820","DOIUrl":"https://doi.org/10.16899/jcm.1283820","url":null,"abstract":"Aim: This study aims to show seasonal differences by analysing the chest disease consultations requested by an emergency unit in summer (June, July, and August) and winter (December, January, and February) months.
 Methods: Patients over the age of 18 years who were directed by an emergency unit to the Department of Chest Diseases between 1 December 2021 and 31 August 2022 and whose thoracic computerized tomography results were available were included in the study. Variables such as the patients’ demographic characteristics, complaints, results of the examinations done in the emergency unit, hospitalization rates, place of hospitalization (hospital ward or intensive care), and pre-diagnosis before hospitalization were evaluated. The statistical significance level was accepted as p < 0.05 in all calculations and statistical analysis of the data was conducted using IBM SPSS Statistics 26 (IBM Corp., Armonk, NY, USA).
 Results: For the 409 patients included in this study, more consultations were requested in the winter months (n = 239, 58.4%). We identified significant differences between the seasonal groups in terms of the complaints and the additional radiological imaging findings of patients consulted in summer and winter months (p < 0.05). The most common complaint in both seasons was shortness of breath. Pleural effusion was less common among the additional radiological findings of both seasons. 
 Conclusion: This study has revealed significant differences between seasonal groups in terms of complaints and additional radiological imaging findings of patients with consultations in summer and winter months. However, there were no significant differences between the seasonal groups in terms of age, sex, pre-diagnosis, place of hospitalization, or main radiological findings.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erhan ŞİMŞEK, Hümeyra ASLANER, Seçkin ÖZSAYDI, Ali Ramazan BENLİ
Aim: Study aimed to assess the states of getting the vaccine and attitudes of the population at the age of 65 and above who was at the risk group in terms of mortality caused by COVID-19 after being informed about the COVID-19 vaccines.
Method: Data, retrospectively scanned. Study population consisted of individuals aged 65 and above who were authorized to get the vaccine in the city center of Kayseri and who had not gotten the COVID-19 vaccine yet by the 1st of June 2021.
Results: According to the decisions of getting the vaccine after phone calls, 45% of the participants decided to get the vaccine while 42.9% stated that they would not get the vaccine. mRNA vaccine was the most preferred vaccine (35.4%) after the phone calls.
Conclusion: Results of study reveal that the attitude toward COVID-19 vaccine can be affected by many personal and non-personal factors.
{"title":"COVID-19 Aşıları Konusunda Bilgilendirme Yapılan 65 Yaş ve Üzeri Bireylerin Aşı Tutumları ve Aşı Tutumlarındaki Değişimin Değerlendirilmesi","authors":"Erhan ŞİMŞEK, Hümeyra ASLANER, Seçkin ÖZSAYDI, Ali Ramazan BENLİ","doi":"10.16899/jcm.1328246","DOIUrl":"https://doi.org/10.16899/jcm.1328246","url":null,"abstract":"Aim: Study aimed to assess the states of getting the vaccine and attitudes of the population at the age of 65 and above who was at the risk group in terms of mortality caused by COVID-19 after being informed about the COVID-19 vaccines.
 
 Method: Data, retrospectively scanned. Study population consisted of individuals aged 65 and above who were authorized to get the vaccine in the city center of Kayseri and who had not gotten the COVID-19 vaccine yet by the 1st of June 2021.
 
 Results: According to the decisions of getting the vaccine after phone calls, 45% of the participants decided to get the vaccine while 42.9% stated that they would not get the vaccine. mRNA vaccine was the most preferred vaccine (35.4%) after the phone calls.
 
 Conclusion: Results of study reveal that the attitude toward COVID-19 vaccine can be affected by many personal and non-personal factors.","PeriodicalId":15449,"journal":{"name":"Journal of contemporary medicine","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136343660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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