Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_629_22
A. Siddiqui, Shadma H. Quazi, Sharjeel H. Khan, Tanaji R. Shende
Objective: Drug use research's main goal is to assist patients in using medications responsibly. The chronic inflammatory disease rheumatoid arthritis (RA) is a condition comprising long-term disability. Disease-modifying antirheumatic drugs (DMARDs) are the mainstay of therapy preventing joint damage. The study's aim was to examine the prescription trends for medications used to treat RA. Methodology: In conjunction with the orthopedic department, a cross-sectional observational study was carried out in a tertiary care hospital for 6 months. The current study included 90 patients in total who met the inclusion and exclusion requirements. Data from patients were collected in a case report format and examined to determine the prescription pattern in all 90 patients participated in the study. Female preponderance was seen in the study with 68.8% of female patients compared to 31.1% of male patients affected by the disease. Patients of the age group of 40–60 years (63.3%) were most commonly affected, followed by 61–70 years (26.6%). A combination of two DMARDs, methotrexate and hydroxychloroquine (HCQ), was the most common in 90% of patients. Triple-DMARD combination was required only in 4.4% of patients. Etoricoxib was most the commonly prescribed analgesic in 28.8% of patients, followed by etodolac in 16.6%. Conclusions: RA affects females more often than males. DMARD combination of methotrexate and HCQ was the most commonly used compared to monotherapy and triple-drug therapy. Drug utilization studies give the prescriber feedback and raise their awareness of the proper usage of medications.
{"title":"Drug prescription patterns and quality of life in rheumatoid arthritis patients at a tertiary care teaching hospital in Central India: A cross-sectional study","authors":"A. Siddiqui, Shadma H. Quazi, Sharjeel H. Khan, Tanaji R. Shende","doi":"10.4103/jdmimsu.jdmimsu_629_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_629_22","url":null,"abstract":"Objective: Drug use research's main goal is to assist patients in using medications responsibly. The chronic inflammatory disease rheumatoid arthritis (RA) is a condition comprising long-term disability. Disease-modifying antirheumatic drugs (DMARDs) are the mainstay of therapy preventing joint damage. The study's aim was to examine the prescription trends for medications used to treat RA. Methodology: In conjunction with the orthopedic department, a cross-sectional observational study was carried out in a tertiary care hospital for 6 months. The current study included 90 patients in total who met the inclusion and exclusion requirements. Data from patients were collected in a case report format and examined to determine the prescription pattern in all 90 patients participated in the study. Female preponderance was seen in the study with 68.8% of female patients compared to 31.1% of male patients affected by the disease. Patients of the age group of 40–60 years (63.3%) were most commonly affected, followed by 61–70 years (26.6%). A combination of two DMARDs, methotrexate and hydroxychloroquine (HCQ), was the most common in 90% of patients. Triple-DMARD combination was required only in 4.4% of patients. Etoricoxib was most the commonly prescribed analgesic in 28.8% of patients, followed by etodolac in 16.6%. Conclusions: RA affects females more often than males. DMARD combination of methotrexate and HCQ was the most commonly used compared to monotherapy and triple-drug therapy. Drug utilization studies give the prescriber feedback and raise their awareness of the proper usage of medications.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"422 - 426"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46802954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_243_22
K. Kamala, S. Sankethguddad
Objectives: Oral submucous fibrosis (OSMF) is a potentially malignant disorder (PMD) which has one of the highest rates of malignant transformation (MT) rate. The aim of this study was to assess the rate of MT of OSMF and to analyze the possible contributory factors such as age, gender, socioeconomic status, habits, various signs and symptoms, and presence of other oral PMDs in a group of OSMF patients attending the Oral Medicine Department. Materials and Methods: Out of 25,200 patients who visited the Outpatient Department of School of Dental Sciences, KIMSDU, Karad, from January 2017 to December 2020, 1342 (5.3%) were diagnosed with OSMF and comprised the study sample, in which 1300 (96.87%) were male and 42 (3.12) were female. All the patients were subjected to incisional biopsy, and clinical diagnosis was confirmed histopathologically. Results: The prevalence of OSMF was 5.3% with male predominance, and majority of OSMF patients were in the age group of 21–30 years. Betel chewer's mucosa and leukoplakia was the most associated lesion. Out of total 1300 male and 42 female OSMF patients, 897 (69%) and 17 (40.47%) showed epithelial dysplasia, and 61 (4.69%) male and 1 (2.38%) female patients showed signs of MT, respectively. Conclusion: The present study highlights the importance of certain risk factors for OSMF that are associated with an increased chance of MT. There is an urgent need of awareness programs through public–private partnership.
{"title":"Potentiality of malignant transformation of oral submucous fibrosis: A prospective study","authors":"K. Kamala, S. Sankethguddad","doi":"10.4103/jdmimsu.jdmimsu_243_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_243_22","url":null,"abstract":"Objectives: Oral submucous fibrosis (OSMF) is a potentially malignant disorder (PMD) which has one of the highest rates of malignant transformation (MT) rate. The aim of this study was to assess the rate of MT of OSMF and to analyze the possible contributory factors such as age, gender, socioeconomic status, habits, various signs and symptoms, and presence of other oral PMDs in a group of OSMF patients attending the Oral Medicine Department. Materials and Methods: Out of 25,200 patients who visited the Outpatient Department of School of Dental Sciences, KIMSDU, Karad, from January 2017 to December 2020, 1342 (5.3%) were diagnosed with OSMF and comprised the study sample, in which 1300 (96.87%) were male and 42 (3.12) were female. All the patients were subjected to incisional biopsy, and clinical diagnosis was confirmed histopathologically. Results: The prevalence of OSMF was 5.3% with male predominance, and majority of OSMF patients were in the age group of 21–30 years. Betel chewer's mucosa and leukoplakia was the most associated lesion. Out of total 1300 male and 42 female OSMF patients, 897 (69%) and 17 (40.47%) showed epithelial dysplasia, and 61 (4.69%) male and 1 (2.38%) female patients showed signs of MT, respectively. Conclusion: The present study highlights the importance of certain risk factors for OSMF that are associated with an increased chance of MT. There is an urgent need of awareness programs through public–private partnership.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"376 - 381"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43275796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_608_22
Sakshi Raju Meshram, Rozina Vishnani
Platelet-rich plasma (PRP) is prepared by using autologous blood plasma enriched with platelet. PRP has been proven to be a successful analog to correct blood loss during cardiac surgery and cardiothoracic bypass. Some authors have demonstrated bone regeneration following tooth extraction with healthy compact bone by using PRP. Typical protocols include either 1 or 2 centrifugation steps to separate whole blood into 3 layers: a top plasma layer, middle leukocyte layer, and bottom red blood cell layer, to collect a concentrate of platelets in plasma. The rationale for use and therapeutic potential of a high concentration of platelets is based on their capacity to supply and release supraphysiologic amounts of essential growth factors and cytokines from their alpha-granules to provide a regenerative stimulus that augments healing and promotes repair in tissues with low healing potential.
{"title":"Action of platelet-rich plasma in facial esthetics and its recovery","authors":"Sakshi Raju Meshram, Rozina Vishnani","doi":"10.4103/jdmimsu.jdmimsu_608_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_608_22","url":null,"abstract":"Platelet-rich plasma (PRP) is prepared by using autologous blood plasma enriched with platelet. PRP has been proven to be a successful analog to correct blood loss during cardiac surgery and cardiothoracic bypass. Some authors have demonstrated bone regeneration following tooth extraction with healthy compact bone by using PRP. Typical protocols include either 1 or 2 centrifugation steps to separate whole blood into 3 layers: a top plasma layer, middle leukocyte layer, and bottom red blood cell layer, to collect a concentrate of platelets in plasma. The rationale for use and therapeutic potential of a high concentration of platelets is based on their capacity to supply and release supraphysiologic amounts of essential growth factors and cytokines from their alpha-granules to provide a regenerative stimulus that augments healing and promotes repair in tissues with low healing potential.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"508 - 512"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42499790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_548_23
Aditya Pundkar, Chetan S. Kulkarni
Fractures of the tibial shaft are the most common fractures to occur in the human body. Number of motor vehicle high-velocity injuries has increased in recent years. Various modalities used for treatment range from immobilization with the cast to open reduction and plating, closed reduction and nailing, and external fixator application. In our study, we have preferred fixation with multiple Ender's nails in a series of three cases with different modes of injury. We found that closed reduction along with internal fixation with Ender's nailing is a better modality in terms of easy technique, cost-effectiveness, small incision size, no soft-tissue damage or stripping, and complication. Ender's nailing is an excellent alternative.
{"title":"Manoeuvring distal tibial shaft fractures with Ender's nailing: Case series","authors":"Aditya Pundkar, Chetan S. Kulkarni","doi":"10.4103/jdmimsu.jdmimsu_548_23","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_548_23","url":null,"abstract":"Fractures of the tibial shaft are the most common fractures to occur in the human body. Number of motor vehicle high-velocity injuries has increased in recent years. Various modalities used for treatment range from immobilization with the cast to open reduction and plating, closed reduction and nailing, and external fixator application. In our study, we have preferred fixation with multiple Ender's nails in a series of three cases with different modes of injury. We found that closed reduction along with internal fixation with Ender's nailing is a better modality in terms of easy technique, cost-effectiveness, small incision size, no soft-tissue damage or stripping, and complication. Ender's nailing is an excellent alternative.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"95 3","pages":"481 - 485"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41306874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_624_22
Sanagat Trupti, Monika Solanki, Yashwant Ramawat, S. Pareek
Background: Being hospitalized, every individual may experience a wide range of short-term or long-term consequences. Hospitalization is not only physical stress, but there are other factors that negatively affect a patient's psychology. This study aimed to assess the effectiveness of bibliotherapy in stress reduction among 9–12 years aged hospitalized children. Materials and Methods: In the research, preexperimental research approach and one group pretest–posttest research design were applied. The study was conducted at Umaid Hospital, Jodhpur, Rajasthan, among 60 hospitalized children. A nonprobability purposive sampling technique was applied for sample selection. Results: The mean posttest stress score (15.35) was less than the mean pretest stress score (24.82). The findings highlighted that bibliotherapy was statistically significant (P < 0.0001) in the reduction of stress of hospitalized children. In terms of association, only the education of children was associated with the stress levels of the children. Conclusion: The findings of the research concluded that bibliotherapy is an effective intervention in stress reduction among hospitalized children. The administrators may utilize this cost-effective intervention in clinical settings for declining stress among children and the adult population.
{"title":"Impact of bibliotherapy in stress reduction among hospitalized children in Western India","authors":"Sanagat Trupti, Monika Solanki, Yashwant Ramawat, S. Pareek","doi":"10.4103/jdmimsu.jdmimsu_624_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_624_22","url":null,"abstract":"Background: Being hospitalized, every individual may experience a wide range of short-term or long-term consequences. Hospitalization is not only physical stress, but there are other factors that negatively affect a patient's psychology. This study aimed to assess the effectiveness of bibliotherapy in stress reduction among 9–12 years aged hospitalized children. Materials and Methods: In the research, preexperimental research approach and one group pretest–posttest research design were applied. The study was conducted at Umaid Hospital, Jodhpur, Rajasthan, among 60 hospitalized children. A nonprobability purposive sampling technique was applied for sample selection. Results: The mean posttest stress score (15.35) was less than the mean pretest stress score (24.82). The findings highlighted that bibliotherapy was statistically significant (P < 0.0001) in the reduction of stress of hospitalized children. In terms of association, only the education of children was associated with the stress levels of the children. Conclusion: The findings of the research concluded that bibliotherapy is an effective intervention in stress reduction among hospitalized children. The administrators may utilize this cost-effective intervention in clinical settings for declining stress among children and the adult population.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"372 - 375"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45491759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_383_22
L. Patnaik, Sumitra Pattanaik, S. Sabat, Sambedana Mohanty, Sumita Sharma
Background: Demonstration, observation, assistance, and performance (DOAP) is a practical session that allows the student to observe a demonstration, assist the performer, perform in a simulated environment, perform under supervision, or perform independently. Competency-based medical education necessitates DOAP sessions that are timely and frequent, criterion based, skillful, and developing. Objective: The objective of the study was to assess the effectiveness of DOAP sessions for training of competencies related to family study among 6th-semester students. Methods: It was a quasi-experimental study conducted over 6 months from November 2021 to April 2022 on 6th-semester undergraduate students coming to the community medicine department during their community posting. The control group consisted of 28 students taught family study by traditional method, and 27 students assigned to the experimental group were taught by DOAP sessions. Demonstration was provided through postgraduates and health-care workers as a role-play followed by recorded video-based sessions. Data were collected at baseline and after intervention. Later, the control group was provided the DOAP sessions. Feedback from all 55 students was collected in a Likert scale. Results: The mean score of the intervention group was significantly higher (P < 0.05). Knowledge score increased 4.07 (confidence interval [CI]: 3.29–4.85) points in the intervention group while 2.35 points in the control group (CI: 1.6–3.1). Objective structured clinical examination score increased 4.72 (CI: 4.0–5.3) points in the intervention group while 2.53 points in the control group (CI: 1.8–3.3). Response rate for feedback was 100% and positive feedback was given by more than 80%. Conclusion: DOAP sessions were found to be effective which may help in implementing DOAP sessions for MBBS students for competencies related to the family study.
{"title":"Effectiveness of demonstration, observation, assistance, and performance sessions for training of competencies related to family study among medical undergraduates","authors":"L. Patnaik, Sumitra Pattanaik, S. Sabat, Sambedana Mohanty, Sumita Sharma","doi":"10.4103/jdmimsu.jdmimsu_383_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_383_22","url":null,"abstract":"Background: Demonstration, observation, assistance, and performance (DOAP) is a practical session that allows the student to observe a demonstration, assist the performer, perform in a simulated environment, perform under supervision, or perform independently. Competency-based medical education necessitates DOAP sessions that are timely and frequent, criterion based, skillful, and developing. Objective: The objective of the study was to assess the effectiveness of DOAP sessions for training of competencies related to family study among 6th-semester students. Methods: It was a quasi-experimental study conducted over 6 months from November 2021 to April 2022 on 6th-semester undergraduate students coming to the community medicine department during their community posting. The control group consisted of 28 students taught family study by traditional method, and 27 students assigned to the experimental group were taught by DOAP sessions. Demonstration was provided through postgraduates and health-care workers as a role-play followed by recorded video-based sessions. Data were collected at baseline and after intervention. Later, the control group was provided the DOAP sessions. Feedback from all 55 students was collected in a Likert scale. Results: The mean score of the intervention group was significantly higher (P < 0.05). Knowledge score increased 4.07 (confidence interval [CI]: 3.29–4.85) points in the intervention group while 2.35 points in the control group (CI: 1.6–3.1). Objective structured clinical examination score increased 4.72 (CI: 4.0–5.3) points in the intervention group while 2.53 points in the control group (CI: 1.8–3.3). Response rate for feedback was 100% and positive feedback was given by more than 80%. Conclusion: DOAP sessions were found to be effective which may help in implementing DOAP sessions for MBBS students for competencies related to the family study.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"405 - 409"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45730931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_517_22
J. Sen, Bitan Sen, Nikhil Akoijam Singh, N. Alaspurkar, Soumya Matturu
Hearing loss can be conductive or sensorineural in nature. Sensorineural hearing loss (SNHL) affects the spiraling organ cochlea of the inner ear, which transforms the sound vibration into a neural signal or transmits it to the auditory part of the brain. Mild-to-severe SNHL, although can be rehabilitated successfully using hearing aids in extreme SNHL, hearing aids merely make the sound louder, distorted, and amplified where the clarity may be not enough for proper understanding to develop speech. Hence, in such cases, the best option for hearing and learning proper speech is a Cochlear implant (CI). Patients with irreversible hearing loss and deaf-mutism, a cochlear implant is an acceptable therapeutic option undertaken under general anesthesia and the hallmark of a successful anesthetic procedure is to provide a bloodless field during surgery.
{"title":"Anesthetic management in pediatric cochlear implant","authors":"J. Sen, Bitan Sen, Nikhil Akoijam Singh, N. Alaspurkar, Soumya Matturu","doi":"10.4103/jdmimsu.jdmimsu_517_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_517_22","url":null,"abstract":"Hearing loss can be conductive or sensorineural in nature. Sensorineural hearing loss (SNHL) affects the spiraling organ cochlea of the inner ear, which transforms the sound vibration into a neural signal or transmits it to the auditory part of the brain. Mild-to-severe SNHL, although can be rehabilitated successfully using hearing aids in extreme SNHL, hearing aids merely make the sound louder, distorted, and amplified where the clarity may be not enough for proper understanding to develop speech. Hence, in such cases, the best option for hearing and learning proper speech is a Cochlear implant (CI). Patients with irreversible hearing loss and deaf-mutism, a cochlear implant is an acceptable therapeutic option undertaken under general anesthesia and the hallmark of a successful anesthetic procedure is to provide a bloodless field during surgery.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"493 - 496"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49178962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_351_22
Gajanan Pisulkar, Ankur Salwan, ShaunakBabanrao Taywade, A. Awasthi, Amit Saoji
Background: Deep vein thrombosis is one of the most common condition affecting adults worldwide. The condition is characterized by the presence of blood clots in the veins. The clots commonly develop in the lower limb veins. Deep vein thrombosis is the most common complication after any lower limb surgery and is a prominent complication post-orthopaedic surgery in individuals of any age due to failure of the valves. Aim and Objectives: The aim of our study is to assess the risk factors following lower limb surgery. Methodology: The individuals who fulfill the inclusion criteria were tested using ultrasonography and duplex color Doppler unit examination at 7.5 MHz and 10 MHz using high frequency probes to assess the presence of thrombus in the deep veins of the individuals who have undergone the surgeries. The assessment was recorded on the assessment sheet and analyzed using SPSS statistical software, and the results were drawn. Results: In this study, the individuals were mostly from the age group 59–68 years and a total of 202 patients were included. 136 patients are diagnosed as suffering from DVT following orthopedic surgery. Conclusion: We conclude that the occurrence of DVT after lower limb surgery depends on various factors such as the duration of surgery, the period of immobilization, prior history of DVT and post-operative stay, and various other factors such as age and gender. We found that extramedullary implants have a relative risk of 2.93. Additionally, we also concluded that clinical signs and symptoms are not reliable measures to identify incidence of DVT.
{"title":"Assessment of risk factors of deep-vein thrombosis after lower limb surgery","authors":"Gajanan Pisulkar, Ankur Salwan, ShaunakBabanrao Taywade, A. Awasthi, Amit Saoji","doi":"10.4103/jdmimsu.jdmimsu_351_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_351_22","url":null,"abstract":"Background: Deep vein thrombosis is one of the most common condition affecting adults worldwide. The condition is characterized by the presence of blood clots in the veins. The clots commonly develop in the lower limb veins. Deep vein thrombosis is the most common complication after any lower limb surgery and is a prominent complication post-orthopaedic surgery in individuals of any age due to failure of the valves. Aim and Objectives: The aim of our study is to assess the risk factors following lower limb surgery. Methodology: The individuals who fulfill the inclusion criteria were tested using ultrasonography and duplex color Doppler unit examination at 7.5 MHz and 10 MHz using high frequency probes to assess the presence of thrombus in the deep veins of the individuals who have undergone the surgeries. The assessment was recorded on the assessment sheet and analyzed using SPSS statistical software, and the results were drawn. Results: In this study, the individuals were mostly from the age group 59–68 years and a total of 202 patients were included. 136 patients are diagnosed as suffering from DVT following orthopedic surgery. Conclusion: We conclude that the occurrence of DVT after lower limb surgery depends on various factors such as the duration of surgery, the period of immobilization, prior history of DVT and post-operative stay, and various other factors such as age and gender. We found that extramedullary implants have a relative risk of 2.93. Additionally, we also concluded that clinical signs and symptoms are not reliable measures to identify incidence of DVT.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"347 - 352"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48117347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_94_23
S. Anwar, N. Tyagi, Yulia Mathias, D. Javed
Background: Oral squamous cell carcinoma (OSCC) is generally converted from precancerous conditions. The conversion rates are mainly linked to various addiction habits and sometimes to sociodemographic profile of patients. The clinical spectrum of oral potentially malignant disorders (OPMDs) varies between geographical districts or from place to place within the same country. The prevalence of this particular malignancy may be reduced by prompt diagnostic and therapeutic action. Aims and Objectives: We focused on the data associated with histo-pathological types of lesion in relation to certain sociodemographic profile and addiction habits in the targeted population. Materials and Methods: We performed 5 years retrospective cross-sectional study from January 2013 to December 2017 in the oral pathology department in systematic manner. Data were collected and compiled in Microsoft Excel and were analyzed through SPSS software. Chi-square, Student's t-test, and Pearson's correlation tests were used to determine the significance of study parameters between groups. Results: Our study suggests a more common relationship of lichen planus with gutkha, pan, and mixed habit; leukoplakia with bidi smoking and mixed habit; verrucous leukoplakia with bidi and cigarette smoking and gutkha chewing; oral submucous fibrosis with pan and gutkha; mild and moderate dysplasia with bidi and alcohol consumption; well-differentiated OSCC and moderately differentiated OSCC with tobacco intake and/or alcohol and poorly differentiated OSCC with alcohol, pan, and bidi. Conclusion: OPMDs and OSCC are more associated with various addiction habits. Cessation of these habits along with early intervention may reduce the burden of disease.
{"title":"A five year retrospective study of oral potentially malignant disorders (Opmds) and oral squamous cell carcinoma (OSCC) and their associated risk factors","authors":"S. Anwar, N. Tyagi, Yulia Mathias, D. Javed","doi":"10.4103/jdmimsu.jdmimsu_94_23","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_94_23","url":null,"abstract":"Background: Oral squamous cell carcinoma (OSCC) is generally converted from precancerous conditions. The conversion rates are mainly linked to various addiction habits and sometimes to sociodemographic profile of patients. The clinical spectrum of oral potentially malignant disorders (OPMDs) varies between geographical districts or from place to place within the same country. The prevalence of this particular malignancy may be reduced by prompt diagnostic and therapeutic action. Aims and Objectives: We focused on the data associated with histo-pathological types of lesion in relation to certain sociodemographic profile and addiction habits in the targeted population. Materials and Methods: We performed 5 years retrospective cross-sectional study from January 2013 to December 2017 in the oral pathology department in systematic manner. Data were collected and compiled in Microsoft Excel and were analyzed through SPSS software. Chi-square, Student's t-test, and Pearson's correlation tests were used to determine the significance of study parameters between groups. Results: Our study suggests a more common relationship of lichen planus with gutkha, pan, and mixed habit; leukoplakia with bidi smoking and mixed habit; verrucous leukoplakia with bidi and cigarette smoking and gutkha chewing; oral submucous fibrosis with pan and gutkha; mild and moderate dysplasia with bidi and alcohol consumption; well-differentiated OSCC and moderately differentiated OSCC with tobacco intake and/or alcohol and poorly differentiated OSCC with alcohol, pan, and bidi. Conclusion: OPMDs and OSCC are more associated with various addiction habits. Cessation of these habits along with early intervention may reduce the burden of disease.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"460 - 467"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48162649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_546_22
Anjali Chimegave, Keta Vagha
Among the most typical reason of sudden, acquired weakness is Guillain-Barré Syndrome characterized by symmetrical ascending paralysis which is frequently sparked by an earlier illness. “Acute Inflammatory Demyelinating Polyneuropathy,” one of the prevailing kinds of Guillian-Barre Syndrome, is divided into four subtypes: acute inflammatory demyelinating polyradiculoneuropathy, Miller Fisher syndrome, acute motor sensory axonal neuropathy, and acute motor axonal neuropathy. Guillain-Barré syndrome can happen at any age, but it is frequently seen in persons over 40 years. More often, males are impacted. This syndrome lasts for 4 weeks, but if it is prolonged than that, it can be categorized as subacute, and if it lasts longer than 8 weeks, it can be classified as chronic. An antecedent infection is present in 70% of patients. The most frequent trigger for Guillain-Barré Syndrome is Campylobacter jejuni, along with the Cytomegalovirus, Zika virus, mycoplasma, hepatitis A and B, and human immunodeficiency virus. The antecedent infection generally occurs 1 to 3 weeks before. The pathogenesis of the disease solely based on the molecular mimicry. In some circumstances, collapse of respiratory system and autonomic dysfunction might make Guillain-Barré Syndrome more difficult to treat.
{"title":"Guillain-Barré syndrome in children: A narrative review","authors":"Anjali Chimegave, Keta Vagha","doi":"10.4103/jdmimsu.jdmimsu_546_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_546_22","url":null,"abstract":"Among the most typical reason of sudden, acquired weakness is Guillain-Barré Syndrome characterized by symmetrical ascending paralysis which is frequently sparked by an earlier illness. “Acute Inflammatory Demyelinating Polyneuropathy,” one of the prevailing kinds of Guillian-Barre Syndrome, is divided into four subtypes: acute inflammatory demyelinating polyradiculoneuropathy, Miller Fisher syndrome, acute motor sensory axonal neuropathy, and acute motor axonal neuropathy. Guillain-Barré syndrome can happen at any age, but it is frequently seen in persons over 40 years. More often, males are impacted. This syndrome lasts for 4 weeks, but if it is prolonged than that, it can be categorized as subacute, and if it lasts longer than 8 weeks, it can be classified as chronic. An antecedent infection is present in 70% of patients. The most frequent trigger for Guillain-Barré Syndrome is Campylobacter jejuni, along with the Cytomegalovirus, Zika virus, mycoplasma, hepatitis A and B, and human immunodeficiency virus. The antecedent infection generally occurs 1 to 3 weeks before. The pathogenesis of the disease solely based on the molecular mimicry. In some circumstances, collapse of respiratory system and autonomic dysfunction might make Guillain-Barré Syndrome more difficult to treat.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"549 - 552"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46006155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}