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The scope of virtual dissection modalities in today's technological era over the conventional anatomical teaching 在当今技术时代,虚拟解剖模式相对于传统解剖教学的范围
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_280_23
V. Anjankar, G. Chavan, Kanchankumar P. Wankhede, Shital Hajare
The branch of medicine is witnessing continuous makeover due to new knowledge or innovations in the field. The novel coronavirus pandemic also changed many of our mindsets. The traditional cadaveric dissection is also not an exception to this. The increasing shortage of cadavers for dissection, lack of public awareness of body donation program, etc., is important factors that generated the need of virtual dissection modalities. Many technologically advanced modalities are available worldwide. India is one of the largest Medical Education Hubs with hundreds of medical institutes across the country. Many multi-national companies and newly launched start-ups from India are focusing their attention toward virtual dissection modalities. These have revolutionaries the concept of teaching and learning through traditional cadaveric dissection. In this article, we presented some of the virtual dissection modalities and their pros/cons over the traditional teaching.
由于该领域的新知识或创新,医学的分支正在经历不断的变革。新型冠状病毒大流行也改变了我们的许多心态。传统的尸体解剖也不例外。用于解剖的尸体日益短缺,公众对尸体捐赠计划缺乏认识等,是产生虚拟解剖模式需求的重要因素。世界各地都有许多技术先进的模式。印度是最大的医学教育中心之一,在全国拥有数百所医学院。许多来自印度的跨国公司和新成立的初创企业正将注意力集中在虚拟解剖模式上。这些都对传统尸体解剖的教学理念产生了革命性的影响。在这篇文章中,我们介绍了一些虚拟解剖模式及其与传统教学相比的优缺点。
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引用次数: 0
The effect of toothbrushing duration on plaque removal: A randomized crossover trial 刷牙时间对牙菌斑清除的影响:一项随机交叉试验
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_16_22
B. Pavani, V. Anu, G. S. Cinthiya, V. Deepika, M. Ayesha, Akkaloori Anitha Reddy
Background: Regular toothbrushing is an important step that removes plaque which is the common risk factor for both periodontitis and dental caries. Commonly prescribed time of brushing by dental professionals is 2 min, despite of which, the average time spent for brushing by the general population is 45 s. Aim: The aim of this study was to determine the relationship between different brushing times from 30 to 180 s, and plaque removal using conventional brushing techniques in the general population. Materials and Methods: Forty participants were included in the study. Study participants brushed for 30, 45, 60, 120, and 180 s randomly. Plaque levels at baseline and after brushing for a specific time period were assessed using the Turesky-modified Quigley–Hein plaque index and a disclosing agent. Results: Plaque removal increased with increased brushing time with maximum removal at 180 s. Conclusions: Dental professionals during health education sessions should highlight the importance of brushing for more than 3 min to achieve maximum plaque removal.
背景:定期刷牙是去除牙菌斑的重要步骤,牙菌斑是牙周炎和龋齿的常见危险因素。牙科专业人员通常规定的刷牙时间为2分钟,尽管如此,普通人群的平均刷牙时间为45秒。目的:本研究的目的是确定30至180秒的不同刷牙时间与普通人群使用传统刷牙技术去除牙菌斑之间的关系。材料和方法:40名参与者被纳入研究。研究参与者随机刷了30、45、60、120和180秒。使用Turesky改良的Quigley–Hein斑块指数和披露剂评估基线和刷牙特定时间后的斑块水平。结果:牙菌斑的去除随着刷牙时间的增加而增加,最大去除时间为180秒。结论:牙科专业人员在健康教育课程中应强调刷牙超过3分钟的重要性,以实现最大限度的牙菌斑去除。
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引用次数: 0
Role of GATA-3 expression in urothelial carcinoma and ITS correlation with p53 by immunohistochemistry 免疫组化分析GATA-3在尿路上皮癌中的表达及其与p53的相关性
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_466_21
Kalpana Chandra, A. Mishra, S. Singh, Nidhish Kumar, Rohit Upadhyay, Umesh Kumar, Amad Atique, Tanwi Singh
Background and Objectives: Urothelial carcinomas are known for divergent differentiation, which often poses diagnostic challenges. The use of immunohistochemistry (IHC) markers helps in differentiating these entities and provides insight into tumor pathogenesis. This study is done with the objective of evaluating significant clinicopathological and histomorphological features of urothelial carcinoma and correlating with GATA-3 and P53 staining. Materials and Methods: A total of 59 cases of urothelial tumors were included in this prospective study. Tissue samples were processed, and H and E-stained slides were evaluated and reported as per the WHO/International Society of Urologic Pathology Classification of bladder tumor 2016. IHC for GATA-3 and p53 was performed using respective monoclonal primary antibodies for GATA-3 and p53. Statistical Analysis: The correlation between GATA-3 and other classical clinicopathological parameters was studied by Chi-square test. P <0.05 was considered statistically significant. Results: In the present study, out of 59 cases, there was a male preponderance with an M: F ratio of 7.4:1 and an age range of 25–85 years. High-grade urothelial carcinoma was the most common histologic subtype. GATA-3 expression was seen in 93.2% of cases. There was a statistically significant correlation of GATA-3 expression with hematuria and dysuria. GATA-3 expression was compared with significant histopathological parameters and a significant correlation of the above parameters with GATA-3 expression was observed. High P53 expression was seen in the majority of high-grade tumors, with only a single case of low-grade UC showing strong P 53 reactivity. Conclusion: GATA-3 is a sensitive IHC marker to diagnose urothelial carcinoma. GATA-3 expression intensity and proportion show significant association with histopathological parameters and may play an important role in stratifying high-risk patients.
背景和目的:众所周知,尿路上皮癌具有分化差异,这通常会对诊断提出挑战。免疫组织化学(IHC)标记物的使用有助于区分这些实体,并提供对肿瘤发病机制的深入了解。本研究的目的是评估尿路上皮癌的重要临床病理和组织形态学特征,并与GATA-3和P53染色相关。材料和方法:本前瞻性研究共纳入59例尿路上皮肿瘤。根据世界卫生组织/国际泌尿病理学学会2016年膀胱肿瘤分类,对组织样本进行处理,并对H和E染色载玻片进行评估和报告。使用GATA-3和p53各自的单克隆一级抗体进行GATA-3的IHC和p53。统计学分析:采用卡方检验研究GATA-3与其他经典临床病理参数的相关性。P<0.05被认为具有统计学意义。结果:在本研究中,在59例病例中,男性占优势,男女比例为7.4:1,年龄范围为25-85岁。高级别尿路上皮癌是最常见的组织学亚型。GATA-3在93.2%的病例中表达。GATA-3的表达与血尿和排尿困难具有统计学意义。将GATA-3的表达与显著的组织病理学参数进行比较,并观察到上述参数与GATA-3表达的显著相关性。P53在大多数高级别肿瘤中高表达,只有一例低级别UC表现出较强的P53反应性。结论:GATA-3是诊断尿路上皮癌的敏感IHC标志物。GATA-3的表达强度和比例与组织病理学参数显著相关,可能在高危患者的分层中发挥重要作用。
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引用次数: 1
Autoimmune clustering of rheumatoid arthritis, Hashimoto's thyroiditis, and pernicious anemia 类风湿性关节炎、桥本甲状腺炎和恶性贫血的自身免疫聚集
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_143_23
Saket Toshniwal, Tejas Toshniwal, S. Acharya, Vaishnavi Toshniwal, Abhinav Kadam
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引用次数: 0
Early verse conventional ambulation on postoperative pain among women with lower segment cesarean section 早期与常规下段剖宫产术后疼痛对照研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_61_23
Versha Negi, Bijaya Mohanta, S. Pareek
Introduction: A cesarean section is a surgical procedure by which one or more babies are delivered through an incision made on a mother's abdomen and uterus. In post cesarean section phase, early ambulation and oral intake are need to be encouraged after declined effects of anesthesia. The present study was conducted with aim to assess the effectiveness of early ambulation on postoperative pain among the women with a lower segment cesarean section. Materials and Methods: The study design was quasi-experimental design and 60 subjects were enrolled by convenient sampling technique. In experimental group, the pain level was assessed after performing breathing exercise, moving legs and hands, upright sitting position, stand and walk with and without support after 10 h of surgery for first 3 postoperative days. While in control group, the mothers were ambulated after 24 h of surgery as per the hospital protocol. Results: There was a significant difference (P < 0.001) between the mean postoperative pain scores after early ambulation among experimental on day 1st, day 2nd, and day 3rd. There was a significant decline in pain scores in experimental group compared to control group (P < 0.001) with days progresses. Conclusion: The early ambulation was significantly effective in reduce postoperative pain scores among the mothers after cesarean section. The present approach may be adopted for the mothers to decline the need of analgesics during postoperative period.
剖宫产是一种外科手术,通过在母亲的腹部和子宫上做一个切口来分娩一个或多个婴儿。剖宫产术后,麻醉效果下降后,应鼓励患儿早期下床和口服。本研究的目的是评估早期下床活动对下段剖宫产术后疼痛的影响。材料与方法:本研究采用准实验设计,采用方便抽样法入组60例受试者。实验组患者术后前3天,术后10 h进行呼吸运动、活动手脚、直立坐姿、站立和无支撑行走后评估疼痛程度。而在对照组中,母亲在手术24小时后按照医院的规定下床。结果:实验组患者术后第1天、第2天、第3天早期下床后平均疼痛评分差异有统计学意义(P < 0.001)。与对照组相比,实验组疼痛评分随治疗时间的延长而显著下降(P < 0.001)。结论:早期下床对降低剖宫产术后产妇疼痛评分有显著效果。本方法可使产妇在术后减少对镇痛药的需要。
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引用次数: 0
Adaptivity and efficacy of web-based generalized exercise training on depression in younger adults: A quasi-experimental feasibility trial 基于网络的广义运动训练对年轻人抑郁症的适应性和疗效:一项准实验可行性试验
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_67_23
S.M. Imran Hossain, Abhishek Sharma, Nidhi Sharma, A. Chahal
Background: Major depressive disorder is one of the most common neuropsychiatric disorders, affecting over one-fifth of the global population. Adolescents and young adults suffering from depression are also at high risk of developing bipolar disorder. Mindfulness-based cognitive therapy is a psychotherapeutic intervention based on Zen meditation (ZM) that aims to reduce the risk of relapse of recurrent depression. Yoga stretch physical and emotional health can be improved and maintained through exercise. Yoga poses stretching exercise (YPSE) positively impacts physical and mental health by down-regulating the hypothalamic–pituitary-adrenal axis and the sympathetic nervous system. Purpose: The purpose of the study is to evaluate the effectiveness of web-based generalized exercise training in young individuals in improving their general, physical, emotional, psychological, and social outcomes. Methods: Montgomery and Asberg depression rating scale is a tool used to evaluate participants who are depressed. The pre-Mini-Mental State Exam (MMSE), Patient Health Questionnaire-9 (PHQ-9), and short-form 36 (SF-36) questionnaires were then completed by the researcher. Before beginning the intervention, the participants were briefed on the importance of the study approach. Following intervention, post-MMSE, PHQ-9, and SF-36 questionnaires were again measured. Results: After following the mindfulness cognitive behavioral therapy (ZM and YPSE) program for 7 days, there are significant improvements in the MMSE, PHQ-9, and SF-36 tests. Conclusions: ZM and YPSE training enhance general, physical, emotional psychological, and social functioning greatly.
背景:重性抑郁障碍是最常见的神经精神障碍之一,影响着全球五分之一以上的人口。患有抑郁症的青少年和年轻人也有患双相情感障碍的高风险。基于正念的认知疗法是一种基于禅宗冥想(ZM)的心理治疗干预,旨在降低复发性抑郁症的复发风险。瑜伽拉伸身体和情绪健康可以通过锻炼来改善和保持。瑜伽体式伸展运动(YPSE)通过下调下丘脑-垂体-肾上腺轴和交感神经系统,对身心健康产生积极影响。目的:本研究的目的是评估基于网络的广泛锻炼训练在改善年轻人的一般、身体、情绪、心理和社会结果方面的有效性。方法:Montgomery和Asberg抑郁评定量表是一种用于评估抑郁参与者的工具。研究人员随后完成了迷你精神状态检查前(MMSE)、患者健康问卷-9(PHQ-9)和简式36(SF-36)问卷。在开始干预之前,向参与者简要介绍了研究方法的重要性。干预后,再次测量MMSE后、PHQ-9和SF-36问卷。结果:在遵循正念认知行为疗法(ZM和YPSE)计划7天后,MMSE、PHQ-9和SF-36测试有显著改善。结论:ZM和YPSE训练能显著提高综合、身体、情感、心理和社会功能。
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引用次数: 0
Effect of resistance exercise in postmastectomy breast cancer survivors: A systematic review 抵抗运动对乳房切除术后乳腺癌幸存者的影响:一项系统综述
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_422_22
Abhishek Sharma, S. Vats, A. Chahal
Background: Breast cancer (BC) impacts over 1.2 million individuals every year worldwide and is the most frequently diagnosed illness in women. Medical treatment options have increased chances of survival, but these procedures frequently have side effects that can negatively impact health status and quality of life (QoL) over the long term QoL. Given that resistance exercise has a special anabolic effect; it may be useful for addressing the effects of BC and its therapy. Materials and Methods: This is an integrative literature review study that includes data search from PubMed, MEDLINE, Scopus, Google Scholar, and the physiotherapy evidence database databases for articles and also crossing English descriptors indexed in the medical subject headings and health sciences descriptors, respectively. The present review is based on the Whittemore and Knafl methodology. Results: A total of 842 patients from 13 studies were included. There was no aggravation subjectively reported or objectively evaluated lymphedema symptoms. Adverse effects were uncommon, mostly of a musculoskeletal in nature, and were successfully handled using conservative methods. The studies we looked at indicate that women who had BC surgically treated can benefit from resistance exercise in terms of their clinical and health outcomes. Results demonstrate that in cancer survivors, pain, physical and emotional functioning, fatigue, depression, and aerobic capacity have improved. Conclusion: It is necessary to conduct rigorously constructed randomized controlled trials (RCTs) that recommend targeted resistance exercise regimens at various stages of BC treatment. To demonstrate the effectiveness of this intervention for the posttreatment care of BC patients and survivors as a method of enhancing health status and QoL, RCTs with complete, standardized reporting of interventions, and adverse events are necessary.
背景:癌症(BC)每年影响全球120多万人,是女性最常见的疾病。医疗选择增加了生存机会,但这些手术经常会产生副作用,对长期生活质量和健康状况产生负面影响。鉴于阻力运动具有特殊的合成代谢作用;它可能有助于解决BC及其治疗的影响。材料和方法:这是一项综合文献综述研究,包括从PubMed、MEDLINE、Scopus、Google Scholar和理疗证据数据库中搜索文章的数据,以及分别在医学主题标题和健康科学描述符中索引的交叉英语描述符。本综述基于Whittemore和Knafl方法论。结果:共纳入13项研究的842名患者。主观报告或客观评估的淋巴水肿症状均未加重。不良反应并不常见,主要是肌肉骨骼性质的,并且使用保守的方法成功处理。我们观察的研究表明,接受BC手术治疗的女性在临床和健康结果方面可以从阻力运动中受益。结果表明,癌症幸存者的疼痛、身体和情绪功能、疲劳、抑郁和有氧能力都有所改善。结论:有必要进行严格构建的随机对照试验(RCT),在BC治疗的各个阶段推荐有针对性的抵抗运动方案。为了证明这种干预措施对BC患者和幸存者的治疗后护理的有效性,作为一种提高健康状况和生活质量的方法,有必要对干预措施和不良事件进行完整、标准化的随机对照试验。
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引用次数: 0
Correlation between cervical spine posture and hand grip strength in healthy collegiate population 健康大学生颈椎姿势与握力的相关性研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_512_22
R. Chauhan, T. Gujral
Introduction: Natural lordotic curves in the cervical spine, which gradually curve back into the apex of the chest and upper back at the base of the skull, are indicative of a healthy cervical spine. Hand grip strength can be determined by determining the amount of maximum force that the hand can squeeze against a dynamometer. Grip strength determines how tightly and securely one can grasp objects. Therefore, this study looked at the relationship between hand grip strength and cervical spine position in a healthy collegiate population. Objective: To study the correlation between cervical spine posture and hand grip strength in healthy collegiate population. Methodology: Total 100 male and female subjects. The subjects for the study were included based on inclusion and exclusion criteria. After explaining the benefits, objectives, and purpose of the study in detail, they were asked to complete the screening form and consent form to conduct the study on the impact of cervical spine position on hand grip strength in a healthy collegiate population. Results: Maximum voluntary contraction stands for Maximum voluntary contraction (MVC) T1, T2, and T3 are highly correlated. There is a weak correlation of MVC with the degree of angle of craniovertebral angle (CVA). Conclusion: This study concluded a positive and statistically significant link between body mass index and MVC and CVA, but not between MCV and CVA.
颈椎的自然前凸曲线,逐渐向后弯曲至胸尖和颅底的上背部,表明颈椎是健康的。手握力可以通过测定手对测力计所能施加的最大力来确定。握力决定了一个人握紧物体的程度。因此,本研究在健康的大学生人群中观察了手握力和颈椎位置之间的关系。目的:探讨健康大学生颈椎姿势与握力的相关性。方法:共100名男女受试者。根据纳入和排除标准纳入本研究的受试者。在详细解释了研究的好处、目的和目的后,他们被要求填写筛查表和同意书,以便在健康的大学生人群中进行颈椎位置对手部握力的影响的研究。结果:最大自主收缩代表最大自主收缩(MVC) T1、T2、T3高度相关。MVC与颅椎角(CVA)夹角程度的相关性较弱。结论:本研究得出体重指数与MVC和CVA呈正相关且具有统计学意义,而MCV和CVA之间无显著相关性。
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引用次数: 0
Orphan disease, drugs, and dentistry: A cumulative review 孤儿病、药物和牙科:一项累积综述
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_246_23
Anand Shankar Sarkar, R. Castelino, Vidya Ajila, D. Darwin
Orphan diseases also known as rare diseases (RDs) are typically hereditary in nature. According to World Health Organization, RDs have a prevalence of 1 in 1000 individuals. Few RDs such as Turner syndrome, Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO), Williams syndrome, neurofibromatosis type I, Gorlin–Goltz, Schimke immuno, and cherubism exhibit oral signs. The disease's great complexity and relatively low occurrence necessitates a diagnostotherapeutic strategy based on the Integration of Several Specializations. Rare illnesses require a worldwide agreement about the planning of future interventions. Dentists are often the first medical professionals to recognize RDs because oral symptoms often appear several years before the corresponding systemic symptoms. The objective of this article is to showcase information about RDs and several activities undertaken over the past decade to address this worldwide issue.
孤儿病也被称为罕见病(RD),通常是遗传性的。根据世界卫生组织的数据,RD的患病率为千分之一。很少有RD表现出口腔症状,如特纳综合征、滑膜炎、痤疮、脓疱病、骨质增生性骨炎(SAPHO)、威廉姆斯综合征、I型神经纤维瘤病、Gorlin–Goltz、Schimke免疫和小天使症。这种疾病非常复杂,发生率相对较低,因此需要采取基于多种专业整合的诊断和治疗策略。罕见疾病需要在全球范围内就未来干预措施的规划达成一致。牙医通常是第一个识别RD的医学专业人员,因为口腔症状通常在相应的全身症状出现前几年出现。本文的目的是展示有关RD的信息以及在过去十年中为解决这一全球问题而开展的几项活动。
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引用次数: 0
Comparative evaluation of setting time and sealing ability of two root end filling materials: An In vitro Study 两种根尖充填材料凝固时间和密封能力的体外比较研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/jdmimsu.jdmimsu_104_21
Vidhi Kharabe, N. Thosar, P. Fulzele, Sphurti P Bane, Suruchi Gupta
Purpose: Incomplete root formation caused due to trauma can lead to problems in future. Treating such open apices teeth pose a challenge. Apexification is one of the treatment options for such teeth with open apex. Thus, this in vitro study intended to assess and compare two commercially available root-end filling materials mineral trioxide aggregate (MTA)-Angelus and Biodentine™ for their setting time and sealing ability. Materials and Methods: This in vitro study assessed the setting time and sealing ability of the two materials; MTA-Angelus and Biodentine™. For setting time evaluation, 30 rings were made and divided into two groups. The evaluation was done using Vicat apparatus. For sealing ability, sixty single rooted teeth were used and were divided into four groups (two experimental and two control). The assessment was done using the linear dye penetration method. Results: Mean setting time of Biodentine and MTA was 29.2 ± 3.84 min and 15.2 ± 2.11 min, respectively. The mean linear dye penetration in MTA group was found to be 0.808 ± 1.094 mm, 3.76 ± 1.05 mm in Biodentine group, 5.28 ± 1.73 mm and 0.05 mm in positive control group. Conclusion: MTA-Angelus demonstrated a faster setting time when compared to biodentine, while biodentine showed to have a superior sealing ability.
目的:外伤引起的牙根不完全形成可导致今后的问题。治疗这样的开放尖牙是一个挑战。根尖成形术是根尖开牙的治疗方法之一。因此,本体外研究旨在评估和比较两种市售的三氧化矿物骨料(MTA)-Angelus和Biodentine™的固化时间和密封能力。材料与方法:体外实验评估两种材料的凝固时间和密封能力;MTA-Angelus和Biodentine™。为评价凝固时间,制作30个环,分为两组。采用维卡仪进行评价。采用60颗单根牙进行封闭,分为4组(2个实验组和2个对照组)。采用线性染料渗透法进行评价。结果:百奥汀和MTA的平均凝固时间分别为29.2±3.84 min和15.2±2.11 min。MTA组平均线性染料穿透率为0.808±1.094 mm,百奥汀组为3.76±1.05 mm,阳性对照组为5.28±1.73 mm, 0.05 mm。结论:MTA-Angelus的凝固时间比biodentine快,而biodentine的密封能力更强。
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引用次数: 0
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Journal of Datta Meghe Institute of Medical Sciences University
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