Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_366_23
R. Kumari, Shruti, Neena Vir Singh, M. Rohit
Background: Diagnosis of cardiovascular disorders in children is a very stressful time for the entire family. During this period family caregivers are anxious about their child's condition. At this time, nurses play an important role to educate the parents or caregivers about the child's health, procedure that has to be performed, and pre- and post-operative care after procedure. This study was conducted to assess the effectiveness of an “instructional module” on knowledge and anxiety of caregivers of children undergoing cardiac catheterization. Materials and Methods: Caregivers of children with congenital heart disease were randomly enrolled in two groups with 30 caregivers in each control and experimental group. Preoperative knowledge and anxiety in both the groups were assessed by a self-structured questionnaire and the State-Trait Anxiety Inventory. An instructional module in the form of a booklet regarding cardiac catheterization was developed and administered to the experimental group while the control group received routine care instuctions. Caregivers' postintervention knowledge was assessed by a structured knowledge questionnaire. Results: Median knowledge score was 2 (2–2) in the control group and 2 (1–2) in the experimental group among caregivers of the children during preintervention phase. The median anxiety score of the caregivers of children underwent cardiac catheterization during preintervention phase was 57.50 (47–61) in the control group and 53 (47.75–56) in the experimental group. The results revealed that there was a significant improvement in knowledge score regarding cardiac catheterization procedure and also there was reduction in the level of anxiety among caregivers in the postintervention experimental group (P < 0.001). Conclusion: The study suggests that the “instructional module” is effective in reducing the anxiety and improving the knowledge levels of caregivers regarding the preoperative and postoperative care of children who underwent cardiac catheterization.
{"title":"Effectiveness of an instructional module on knowledge and anxiety of caregivers of children undergoing cardiac catheterization – An experimental study","authors":"R. Kumari, Shruti, Neena Vir Singh, M. Rohit","doi":"10.4103/jdmimsu.jdmimsu_366_23","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_366_23","url":null,"abstract":"Background: Diagnosis of cardiovascular disorders in children is a very stressful time for the entire family. During this period family caregivers are anxious about their child's condition. At this time, nurses play an important role to educate the parents or caregivers about the child's health, procedure that has to be performed, and pre- and post-operative care after procedure. This study was conducted to assess the effectiveness of an “instructional module” on knowledge and anxiety of caregivers of children undergoing cardiac catheterization. Materials and Methods: Caregivers of children with congenital heart disease were randomly enrolled in two groups with 30 caregivers in each control and experimental group. Preoperative knowledge and anxiety in both the groups were assessed by a self-structured questionnaire and the State-Trait Anxiety Inventory. An instructional module in the form of a booklet regarding cardiac catheterization was developed and administered to the experimental group while the control group received routine care instuctions. Caregivers' postintervention knowledge was assessed by a structured knowledge questionnaire. Results: Median knowledge score was 2 (2–2) in the control group and 2 (1–2) in the experimental group among caregivers of the children during preintervention phase. The median anxiety score of the caregivers of children underwent cardiac catheterization during preintervention phase was 57.50 (47–61) in the control group and 53 (47.75–56) in the experimental group. The results revealed that there was a significant improvement in knowledge score regarding cardiac catheterization procedure and also there was reduction in the level of anxiety among caregivers in the postintervention experimental group (P < 0.001). Conclusion: The study suggests that the “instructional module” is effective in reducing the anxiety and improving the knowledge levels of caregivers regarding the preoperative and postoperative care of children who underwent cardiac catheterization.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"438 - 443"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48334465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_61_23
Versha Negi, Bijaya Mohanta, S. Pareek
Introduction: A cesarean section is a surgical procedure by which one or more babies are delivered through an incision made on a mother's abdomen and uterus. In post cesarean section phase, early ambulation and oral intake are need to be encouraged after declined effects of anesthesia. The present study was conducted with aim to assess the effectiveness of early ambulation on postoperative pain among the women with a lower segment cesarean section. Materials and Methods: The study design was quasi-experimental design and 60 subjects were enrolled by convenient sampling technique. In experimental group, the pain level was assessed after performing breathing exercise, moving legs and hands, upright sitting position, stand and walk with and without support after 10 h of surgery for first 3 postoperative days. While in control group, the mothers were ambulated after 24 h of surgery as per the hospital protocol. Results: There was a significant difference (P < 0.001) between the mean postoperative pain scores after early ambulation among experimental on day 1st, day 2nd, and day 3rd. There was a significant decline in pain scores in experimental group compared to control group (P < 0.001) with days progresses. Conclusion: The early ambulation was significantly effective in reduce postoperative pain scores among the mothers after cesarean section. The present approach may be adopted for the mothers to decline the need of analgesics during postoperative period.
{"title":"Early verse conventional ambulation on postoperative pain among women with lower segment cesarean section","authors":"Versha Negi, Bijaya Mohanta, S. Pareek","doi":"10.4103/jdmimsu.jdmimsu_61_23","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_61_23","url":null,"abstract":"Introduction: A cesarean section is a surgical procedure by which one or more babies are delivered through an incision made on a mother's abdomen and uterus. In post cesarean section phase, early ambulation and oral intake are need to be encouraged after declined effects of anesthesia. The present study was conducted with aim to assess the effectiveness of early ambulation on postoperative pain among the women with a lower segment cesarean section. Materials and Methods: The study design was quasi-experimental design and 60 subjects were enrolled by convenient sampling technique. In experimental group, the pain level was assessed after performing breathing exercise, moving legs and hands, upright sitting position, stand and walk with and without support after 10 h of surgery for first 3 postoperative days. While in control group, the mothers were ambulated after 24 h of surgery as per the hospital protocol. Results: There was a significant difference (P < 0.001) between the mean postoperative pain scores after early ambulation among experimental on day 1st, day 2nd, and day 3rd. There was a significant decline in pain scores in experimental group compared to control group (P < 0.001) with days progresses. Conclusion: The early ambulation was significantly effective in reduce postoperative pain scores among the mothers after cesarean section. The present approach may be adopted for the mothers to decline the need of analgesics during postoperative period.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"455 - 459"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46204721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_371_23
Bivek Singh, Prabakaran Shankar
{"title":"Knowledge of research before and after a webinar for health science students","authors":"Bivek Singh, Prabakaran Shankar","doi":"10.4103/jdmimsu.jdmimsu_371_23","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_371_23","url":null,"abstract":"","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"583 - 584"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43163755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_16_22
B. Pavani, V. Anu, G. S. Cinthiya, V. Deepika, M. Ayesha, Akkaloori Anitha Reddy
Background: Regular toothbrushing is an important step that removes plaque which is the common risk factor for both periodontitis and dental caries. Commonly prescribed time of brushing by dental professionals is 2 min, despite of which, the average time spent for brushing by the general population is 45 s. Aim: The aim of this study was to determine the relationship between different brushing times from 30 to 180 s, and plaque removal using conventional brushing techniques in the general population. Materials and Methods: Forty participants were included in the study. Study participants brushed for 30, 45, 60, 120, and 180 s randomly. Plaque levels at baseline and after brushing for a specific time period were assessed using the Turesky-modified Quigley–Hein plaque index and a disclosing agent. Results: Plaque removal increased with increased brushing time with maximum removal at 180 s. Conclusions: Dental professionals during health education sessions should highlight the importance of brushing for more than 3 min to achieve maximum plaque removal.
{"title":"The effect of toothbrushing duration on plaque removal: A randomized crossover trial","authors":"B. Pavani, V. Anu, G. S. Cinthiya, V. Deepika, M. Ayesha, Akkaloori Anitha Reddy","doi":"10.4103/jdmimsu.jdmimsu_16_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_16_22","url":null,"abstract":"Background: Regular toothbrushing is an important step that removes plaque which is the common risk factor for both periodontitis and dental caries. Commonly prescribed time of brushing by dental professionals is 2 min, despite of which, the average time spent for brushing by the general population is 45 s. Aim: The aim of this study was to determine the relationship between different brushing times from 30 to 180 s, and plaque removal using conventional brushing techniques in the general population. Materials and Methods: Forty participants were included in the study. Study participants brushed for 30, 45, 60, 120, and 180 s randomly. Plaque levels at baseline and after brushing for a specific time period were assessed using the Turesky-modified Quigley–Hein plaque index and a disclosing agent. Results: Plaque removal increased with increased brushing time with maximum removal at 180 s. Conclusions: Dental professionals during health education sessions should highlight the importance of brushing for more than 3 min to achieve maximum plaque removal.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"369 - 371"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41415114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_466_21
Kalpana Chandra, A. Mishra, S. Singh, Nidhish Kumar, Rohit Upadhyay, Umesh Kumar, Amad Atique, Tanwi Singh
Background and Objectives: Urothelial carcinomas are known for divergent differentiation, which often poses diagnostic challenges. The use of immunohistochemistry (IHC) markers helps in differentiating these entities and provides insight into tumor pathogenesis. This study is done with the objective of evaluating significant clinicopathological and histomorphological features of urothelial carcinoma and correlating with GATA-3 and P53 staining. Materials and Methods: A total of 59 cases of urothelial tumors were included in this prospective study. Tissue samples were processed, and H and E-stained slides were evaluated and reported as per the WHO/International Society of Urologic Pathology Classification of bladder tumor 2016. IHC for GATA-3 and p53 was performed using respective monoclonal primary antibodies for GATA-3 and p53. Statistical Analysis: The correlation between GATA-3 and other classical clinicopathological parameters was studied by Chi-square test. P <0.05 was considered statistically significant. Results: In the present study, out of 59 cases, there was a male preponderance with an M: F ratio of 7.4:1 and an age range of 25–85 years. High-grade urothelial carcinoma was the most common histologic subtype. GATA-3 expression was seen in 93.2% of cases. There was a statistically significant correlation of GATA-3 expression with hematuria and dysuria. GATA-3 expression was compared with significant histopathological parameters and a significant correlation of the above parameters with GATA-3 expression was observed. High P53 expression was seen in the majority of high-grade tumors, with only a single case of low-grade UC showing strong P 53 reactivity. Conclusion: GATA-3 is a sensitive IHC marker to diagnose urothelial carcinoma. GATA-3 expression intensity and proportion show significant association with histopathological parameters and may play an important role in stratifying high-risk patients.
{"title":"Role of GATA-3 expression in urothelial carcinoma and ITS correlation with p53 by immunohistochemistry","authors":"Kalpana Chandra, A. Mishra, S. Singh, Nidhish Kumar, Rohit Upadhyay, Umesh Kumar, Amad Atique, Tanwi Singh","doi":"10.4103/jdmimsu.jdmimsu_466_21","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_466_21","url":null,"abstract":"Background and Objectives: Urothelial carcinomas are known for divergent differentiation, which often poses diagnostic challenges. The use of immunohistochemistry (IHC) markers helps in differentiating these entities and provides insight into tumor pathogenesis. This study is done with the objective of evaluating significant clinicopathological and histomorphological features of urothelial carcinoma and correlating with GATA-3 and P53 staining. Materials and Methods: A total of 59 cases of urothelial tumors were included in this prospective study. Tissue samples were processed, and H and E-stained slides were evaluated and reported as per the WHO/International Society of Urologic Pathology Classification of bladder tumor 2016. IHC for GATA-3 and p53 was performed using respective monoclonal primary antibodies for GATA-3 and p53. Statistical Analysis: The correlation between GATA-3 and other classical clinicopathological parameters was studied by Chi-square test. P <0.05 was considered statistically significant. Results: In the present study, out of 59 cases, there was a male preponderance with an M: F ratio of 7.4:1 and an age range of 25–85 years. High-grade urothelial carcinoma was the most common histologic subtype. GATA-3 expression was seen in 93.2% of cases. There was a statistically significant correlation of GATA-3 expression with hematuria and dysuria. GATA-3 expression was compared with significant histopathological parameters and a significant correlation of the above parameters with GATA-3 expression was observed. High P53 expression was seen in the majority of high-grade tumors, with only a single case of low-grade UC showing strong P 53 reactivity. Conclusion: GATA-3 is a sensitive IHC marker to diagnose urothelial carcinoma. GATA-3 expression intensity and proportion show significant association with histopathological parameters and may play an important role in stratifying high-risk patients.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"392 - 397"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48279482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_143_23
Saket Toshniwal, Tejas Toshniwal, S. Acharya, Vaishnavi Toshniwal, Abhinav Kadam
{"title":"Autoimmune clustering of rheumatoid arthritis, Hashimoto's thyroiditis, and pernicious anemia","authors":"Saket Toshniwal, Tejas Toshniwal, S. Acharya, Vaishnavi Toshniwal, Abhinav Kadam","doi":"10.4103/jdmimsu.jdmimsu_143_23","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_143_23","url":null,"abstract":"","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"585 - 586"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47467557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_512_22
R. Chauhan, T. Gujral
Introduction: Natural lordotic curves in the cervical spine, which gradually curve back into the apex of the chest and upper back at the base of the skull, are indicative of a healthy cervical spine. Hand grip strength can be determined by determining the amount of maximum force that the hand can squeeze against a dynamometer. Grip strength determines how tightly and securely one can grasp objects. Therefore, this study looked at the relationship between hand grip strength and cervical spine position in a healthy collegiate population. Objective: To study the correlation between cervical spine posture and hand grip strength in healthy collegiate population. Methodology: Total 100 male and female subjects. The subjects for the study were included based on inclusion and exclusion criteria. After explaining the benefits, objectives, and purpose of the study in detail, they were asked to complete the screening form and consent form to conduct the study on the impact of cervical spine position on hand grip strength in a healthy collegiate population. Results: Maximum voluntary contraction stands for Maximum voluntary contraction (MVC) T1, T2, and T3 are highly correlated. There is a weak correlation of MVC with the degree of angle of craniovertebral angle (CVA). Conclusion: This study concluded a positive and statistically significant link between body mass index and MVC and CVA, but not between MCV and CVA.
{"title":"Correlation between cervical spine posture and hand grip strength in healthy collegiate population","authors":"R. Chauhan, T. Gujral","doi":"10.4103/jdmimsu.jdmimsu_512_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_512_22","url":null,"abstract":"Introduction: Natural lordotic curves in the cervical spine, which gradually curve back into the apex of the chest and upper back at the base of the skull, are indicative of a healthy cervical spine. Hand grip strength can be determined by determining the amount of maximum force that the hand can squeeze against a dynamometer. Grip strength determines how tightly and securely one can grasp objects. Therefore, this study looked at the relationship between hand grip strength and cervical spine position in a healthy collegiate population. Objective: To study the correlation between cervical spine posture and hand grip strength in healthy collegiate population. Methodology: Total 100 male and female subjects. The subjects for the study were included based on inclusion and exclusion criteria. After explaining the benefits, objectives, and purpose of the study in detail, they were asked to complete the screening form and consent form to conduct the study on the impact of cervical spine position on hand grip strength in a healthy collegiate population. Results: Maximum voluntary contraction stands for Maximum voluntary contraction (MVC) T1, T2, and T3 are highly correlated. There is a weak correlation of MVC with the degree of angle of craniovertebral angle (CVA). Conclusion: This study concluded a positive and statistically significant link between body mass index and MVC and CVA, but not between MCV and CVA.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"444 - 449"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46336128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_422_22
Abhishek Sharma, S. Vats, A. Chahal
Background: Breast cancer (BC) impacts over 1.2 million individuals every year worldwide and is the most frequently diagnosed illness in women. Medical treatment options have increased chances of survival, but these procedures frequently have side effects that can negatively impact health status and quality of life (QoL) over the long term QoL. Given that resistance exercise has a special anabolic effect; it may be useful for addressing the effects of BC and its therapy. Materials and Methods: This is an integrative literature review study that includes data search from PubMed, MEDLINE, Scopus, Google Scholar, and the physiotherapy evidence database databases for articles and also crossing English descriptors indexed in the medical subject headings and health sciences descriptors, respectively. The present review is based on the Whittemore and Knafl methodology. Results: A total of 842 patients from 13 studies were included. There was no aggravation subjectively reported or objectively evaluated lymphedema symptoms. Adverse effects were uncommon, mostly of a musculoskeletal in nature, and were successfully handled using conservative methods. The studies we looked at indicate that women who had BC surgically treated can benefit from resistance exercise in terms of their clinical and health outcomes. Results demonstrate that in cancer survivors, pain, physical and emotional functioning, fatigue, depression, and aerobic capacity have improved. Conclusion: It is necessary to conduct rigorously constructed randomized controlled trials (RCTs) that recommend targeted resistance exercise regimens at various stages of BC treatment. To demonstrate the effectiveness of this intervention for the posttreatment care of BC patients and survivors as a method of enhancing health status and QoL, RCTs with complete, standardized reporting of interventions, and adverse events are necessary.
{"title":"Effect of resistance exercise in postmastectomy breast cancer survivors: A systematic review","authors":"Abhishek Sharma, S. Vats, A. Chahal","doi":"10.4103/jdmimsu.jdmimsu_422_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_422_22","url":null,"abstract":"Background: Breast cancer (BC) impacts over 1.2 million individuals every year worldwide and is the most frequently diagnosed illness in women. Medical treatment options have increased chances of survival, but these procedures frequently have side effects that can negatively impact health status and quality of life (QoL) over the long term QoL. Given that resistance exercise has a special anabolic effect; it may be useful for addressing the effects of BC and its therapy. Materials and Methods: This is an integrative literature review study that includes data search from PubMed, MEDLINE, Scopus, Google Scholar, and the physiotherapy evidence database databases for articles and also crossing English descriptors indexed in the medical subject headings and health sciences descriptors, respectively. The present review is based on the Whittemore and Knafl methodology. Results: A total of 842 patients from 13 studies were included. There was no aggravation subjectively reported or objectively evaluated lymphedema symptoms. Adverse effects were uncommon, mostly of a musculoskeletal in nature, and were successfully handled using conservative methods. The studies we looked at indicate that women who had BC surgically treated can benefit from resistance exercise in terms of their clinical and health outcomes. Results demonstrate that in cancer survivors, pain, physical and emotional functioning, fatigue, depression, and aerobic capacity have improved. Conclusion: It is necessary to conduct rigorously constructed randomized controlled trials (RCTs) that recommend targeted resistance exercise regimens at various stages of BC treatment. To demonstrate the effectiveness of this intervention for the posttreatment care of BC patients and survivors as a method of enhancing health status and QoL, RCTs with complete, standardized reporting of interventions, and adverse events are necessary.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"539 - 548"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47866460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_246_23
Anand Shankar Sarkar, R. Castelino, Vidya Ajila, D. Darwin
Orphan diseases also known as rare diseases (RDs) are typically hereditary in nature. According to World Health Organization, RDs have a prevalence of 1 in 1000 individuals. Few RDs such as Turner syndrome, Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO), Williams syndrome, neurofibromatosis type I, Gorlin–Goltz, Schimke immuno, and cherubism exhibit oral signs. The disease's great complexity and relatively low occurrence necessitates a diagnostotherapeutic strategy based on the Integration of Several Specializations. Rare illnesses require a worldwide agreement about the planning of future interventions. Dentists are often the first medical professionals to recognize RDs because oral symptoms often appear several years before the corresponding systemic symptoms. The objective of this article is to showcase information about RDs and several activities undertaken over the past decade to address this worldwide issue.
{"title":"Orphan disease, drugs, and dentistry: A cumulative review","authors":"Anand Shankar Sarkar, R. Castelino, Vidya Ajila, D. Darwin","doi":"10.4103/jdmimsu.jdmimsu_246_23","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_246_23","url":null,"abstract":"Orphan diseases also known as rare diseases (RDs) are typically hereditary in nature. According to World Health Organization, RDs have a prevalence of 1 in 1000 individuals. Few RDs such as Turner syndrome, Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO), Williams syndrome, neurofibromatosis type I, Gorlin–Goltz, Schimke immuno, and cherubism exhibit oral signs. The disease's great complexity and relatively low occurrence necessitates a diagnostotherapeutic strategy based on the Integration of Several Specializations. Rare illnesses require a worldwide agreement about the planning of future interventions. Dentists are often the first medical professionals to recognize RDs because oral symptoms often appear several years before the corresponding systemic symptoms. The objective of this article is to showcase information about RDs and several activities undertaken over the past decade to address this worldwide issue.","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"553 - 558"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49293237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-01DOI: 10.4103/jdmimsu.jdmimsu_522_22
R. Sarode, Twinkle Pawar, S. Acharya
{"title":"Sick sinus syndrome in hyperthyroidism","authors":"R. Sarode, Twinkle Pawar, S. Acharya","doi":"10.4103/jdmimsu.jdmimsu_522_22","DOIUrl":"https://doi.org/10.4103/jdmimsu.jdmimsu_522_22","url":null,"abstract":"","PeriodicalId":15592,"journal":{"name":"Journal of Datta Meghe Institute of Medical Sciences University","volume":"18 1","pages":"589 - 590"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48359774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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