首页 > 最新文献

Journal of Food Science and Nutrition Research最新文献

英文 中文
Nutrition Information System (SISFORNUTRIMIL) Application with Food Record Online for Indonesia Pregnant Women: Protocol for Randomized Controlled Trial 营养信息系统(SISFORNUTRIMIL)与印度尼西亚孕妇在线食品记录的应用:随机对照试验方案
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-11000099
Koeryaman Mt, Pallikadavath S, I. R, Kandala N
Background The pregnant women and family may not have the necessary knowledge and skills to estimate nutrient value in line with dietary targets and the guidelines, i.e. they do not know whether or not they are consuming the right amount of nutrition needed during pregnancy. The aims of this randomized controlled trial (RCT) is to examine the effectiveness of SISFORNUTRIMIL application on maternal eating behaviour and clinical indicators such as weight gain, blood pressure, biochemical measurement, and pregnancy outcome. Methods The study recruits 109 participants with eligible criteria during November 3 2019, and mid-January 2020. The allocation of participants is 1:1 to the SISFORNUTRIMIL application user (56 participants) and non-user application (53 J Food Sci Nutr Res 2022; 5 (2): 570-581 DOI: 10.26502/jfsnr.2642-11000099 Journal of Food Science and Nutrition Research Vol. 5 No. 2 June 2022. [ISSN 2642-1100] 571 participants), with criteria: singleton pregnancy (2226 weeks), mother age between 19-30 years old), have monthly income and literate. The participants in the intervention group received a face-to-face visit and standardised prenatal care and diet advice from healthcare professionals which the intervention group used a web-based app for 12 weeks to follow food choices and input their dietary intake on the dietary record that had synchronised total calorie estimation. At the same time, the control group received the usual care and paper-based method only. Discussion This is the first randomized controlled trial to examine the effectiveness of the SISFORNUTIMIL application. Additionally, the researcher's personal efforts to reduce morbidity and mortality rates caused by poor nutrition. The frameworks have focused on nutrition self-monitoring interventions concerning calorie intake and food diversity consumed. The application's interface comprises records of dietary intake, food advice, and information on adequate nutrition that follow national guidelines. Trial registration: ISRCTN Registry: ISRCTN42690828. Date of registration: 22 October 2019.
孕妇及其家庭可能没有必要的知识和技能来根据膳食目标和指南估计营养价值,即他们不知道自己在怀孕期间是否摄入了所需的适量营养。本随机对照试验(RCT)的目的是检查SISFORNUTRIMIL应用对产妇饮食行为和临床指标(如体重增加、血压、生化测量和妊娠结局)的有效性。方法在2019年11月3日和2020年1月中旬招募109名符合条件的参与者。参与者按1:1的比例分配给SISFORNUTRIMIL应用程序用户(56名参与者)和非用户应用程序(53 J Food science nur Res 2022;DOI: 10.26502/jfsnr. 5(2): 570-581。食品科学与营养研究Vol. 5 No. 2 2022年6月。[ISSN 2642-1100] 571名参与者),标准:单胎妊娠(2226周),母亲年龄在19-30岁之间),有月收入,识字。干预组的参与者接受了面对面的访问,并接受了医疗保健专业人员的标准化产前护理和饮食建议。干预组使用基于网络的应用程序进行了12周的食物选择,并将他们的饮食摄入量输入到与总卡路里估算同步的饮食记录中。与此同时,对照组仅接受常规护理和纸本方法。这是检验SISFORNUTIMIL应用有效性的第一个随机对照试验。此外,研究人员为减少营养不良引起的发病率和死亡率所作的个人努力。这些框架的重点是关于卡路里摄入量和所消耗食物多样性的营养自我监测干预措施。该应用程序的界面包括膳食摄入量记录、食品建议和符合国家指南的充足营养信息。试验注册:ISRCTN注册:ISRCTN42690828。注册日期:2019年10月22日。
{"title":"Nutrition Information System (SISFORNUTRIMIL) Application with Food Record Online for Indonesia Pregnant Women: Protocol for Randomized Controlled Trial","authors":"Koeryaman Mt, Pallikadavath S, I. R, Kandala N","doi":"10.26502/jfsnr.2642-11000099","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-11000099","url":null,"abstract":"Background The pregnant women and family may not have the necessary knowledge and skills to estimate nutrient value in line with dietary targets and the guidelines, i.e. they do not know whether or not they are consuming the right amount of nutrition needed during pregnancy. The aims of this randomized controlled trial (RCT) is to examine the effectiveness of SISFORNUTRIMIL application on maternal eating behaviour and clinical indicators such as weight gain, blood pressure, biochemical measurement, and pregnancy outcome. Methods The study recruits 109 participants with eligible criteria during November 3 2019, and mid-January 2020. The allocation of participants is 1:1 to the SISFORNUTRIMIL application user (56 participants) and non-user application (53 J Food Sci Nutr Res 2022; 5 (2): 570-581 DOI: 10.26502/jfsnr.2642-11000099 Journal of Food Science and Nutrition Research Vol. 5 No. 2 June 2022. [ISSN 2642-1100] 571 participants), with criteria: singleton pregnancy (2226 weeks), mother age between 19-30 years old), have monthly income and literate. The participants in the intervention group received a face-to-face visit and standardised prenatal care and diet advice from healthcare professionals which the intervention group used a web-based app for 12 weeks to follow food choices and input their dietary intake on the dietary record that had synchronised total calorie estimation. At the same time, the control group received the usual care and paper-based method only. Discussion This is the first randomized controlled trial to examine the effectiveness of the SISFORNUTIMIL application. Additionally, the researcher's personal efforts to reduce morbidity and mortality rates caused by poor nutrition. The frameworks have focused on nutrition self-monitoring interventions concerning calorie intake and food diversity consumed. The application's interface comprises records of dietary intake, food advice, and information on adequate nutrition that follow national guidelines. Trial registration: ISRCTN Registry: ISRCTN42690828. Date of registration: 22 October 2019.","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80951949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Adherence to Combined Exercise and Dietary Intervention in Patients with Gastrointestinal Cancer Undergoing Neo-Adjuvant Therapy: An Open-Label, Pilot, Randomized Controlled Trial 接受新辅助治疗的胃肠癌患者坚持运动和饮食联合干预:一项开放标签、先导、随机对照试验
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-110000113
Velho S, Moço S, Capitão C, B. M., C. L.
Background: To assess adherence of gastrointestinal cancer patients to a Combined Exercise and Dietary Intervention (CEDI) during neo-adjuvant chemotherapy. Methods: Parallel randomized controlled, open label, pilot trial. A table from a web based randomization system was used to allocate treatments. 46 patients were screened at diagnosis of esophageal, gastric, pancreatic and rectal cancer from June 2018 to November 2019 at a teaching hospital in Loures, 39 were randomized. A planned interim analysis was performed and results are herein presented. Patients were randomized to receive either 8 week individualized CEDI, with moderate aerobic and resistance training, dietary counseling and oral nutritional supplements or standard care. Follow up was conducted after neo-adjuvant treatment. Main outcome measures were adherence to CEDI, change in weight, body composition and functional status. Adherence to CEDI was analyzed with an intention to treat approach, other outcome measures were analyzed with a per protocol approach. Data analysis was conducted with Chi-square test or Fisher exact test and t-test or Mann Whitney U test. Effect size was computed with Cohen’s d for t tests and r for Mann-Whitney U tests. Paired-samples t test or Wilcoxon Signed Rank Test were used to analyze longitudinal data. Results: 39 patients (CEDI n=19 or control n=20) were randomized and included in the intention to treat analysis (29 (74.3%) male, median age 63.5 (Interquartile Range (IQR):11.75)).
背景:评估胃肠道肿瘤患者在新辅助化疗期间对运动和饮食联合干预(CEDI)的依从性。方法:平行、随机对照、开放标签、先导试验。使用基于网络的随机化系统的表格来分配治疗。对2018年6月至2019年11月在法国洛雷斯市某教学医院诊断为食管癌、胃癌、胰腺癌和直肠癌的患者46例进行筛查,其中39例随机抽取。进行了计划的中期分析,并提出了结果。患者随机接受8周的个体化CEDI,包括适度的有氧和阻力训练、饮食咨询和口服营养补充剂或标准治疗。新辅助治疗后随访。主要结局指标为遵守CEDI、体重变化、身体组成和功能状态。采用意向治疗方法分析对CEDI的依从性,其他结果测量采用每个方案方法分析。数据分析采用卡方检验或Fisher精确检验、t检验或Mann Whitney U检验。效应量用Cohen 's d (t检验)和r (Mann-Whitney U检验)计算。纵向资料分析采用配对样本t检验或Wilcoxon sign Rank检验。结果:39例患者(CEDI n=19或对照组n=20)被随机纳入意向治疗分析(29例(74.3%)男性,中位年龄63.5岁(四分位间距(IQR):11.75)。
{"title":"Adherence to Combined Exercise and Dietary Intervention in Patients with Gastrointestinal Cancer Undergoing Neo-Adjuvant Therapy: An Open-Label, Pilot, Randomized Controlled Trial","authors":"Velho S, Moço S, Capitão C, B. M., C. L.","doi":"10.26502/jfsnr.2642-110000113","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-110000113","url":null,"abstract":"Background: To assess adherence of gastrointestinal cancer patients to a Combined Exercise and Dietary Intervention (CEDI) during neo-adjuvant chemotherapy. Methods: Parallel randomized controlled, open label, pilot trial. A table from a web based randomization system was used to allocate treatments. 46 patients were screened at diagnosis of esophageal, gastric, pancreatic and rectal cancer from June 2018 to November 2019 at a teaching hospital in Loures, 39 were randomized. A planned interim analysis was performed and results are herein presented. Patients were randomized to receive either 8 week individualized CEDI, with moderate aerobic and resistance training, dietary counseling and oral nutritional supplements or standard care. Follow up was conducted after neo-adjuvant treatment. Main outcome measures were adherence to CEDI, change in weight, body composition and functional status. Adherence to CEDI was analyzed with an intention to treat approach, other outcome measures were analyzed with a per protocol approach. Data analysis was conducted with Chi-square test or Fisher exact test and t-test or Mann Whitney U test. Effect size was computed with Cohen’s d for t tests and r for Mann-Whitney U tests. Paired-samples t test or Wilcoxon Signed Rank Test were used to analyze longitudinal data. Results: 39 patients (CEDI n=19 or control n=20) were randomized and included in the intention to treat analysis (29 (74.3%) male, median age 63.5 (Interquartile Range (IQR):11.75)).","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87978204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double Burden of Obesity and Hypertension in the Elderly: Cross- Sectional Study of Prevalence and Risk Factors in Foumban, West Region, Cameroon 老年人肥胖和高血压的双重负担:喀麦隆西部富班地区患病率和危险因素的横断面研究
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-110000105
W. Dakam, P. Mintom, Chetou Mbete, Christine Fernande Nyangono Biyegue
Objective: To identify the factors contributing to the double burden of obesity and hypertension in the elderly Cameroonians. Methodology: A total of 172 participants aged over 60 were enrolled in a cross- sectional study carried out in households in the city of Foumban. The sociodemographic and nutritional data of each participant were collected using a questionnaire adapted from the WHO STEP wise approach while anthropometric and hemodynamic measurements were recorded. Based on the WHO guidelines and ACC/AHA definitions, three patterns of the double burden of obesity and hypertension were investigated: i) generalized obesity/hypertension (GO/H), ii) abdominal obesity/hypertension (AO/H) and iii) combined generalized and abdominal obesity/hypertension (CO/H). Results: Prevalence of the different patterns of the double burden of obesity and hypertension were: 29.7% (CO/H), 37.8% (GO/H), and 46.5% (AO/H). Type of marriage, source of income, consumption of fat and starchy recipes, consumption of refined sugars and family history were significantly linked to the AO/H pattern while consumption of refined sugars and irregular consumption of fruits were associated with the GO/H pattern. Conclusion: Abdominal obesity appears to be the most frequent pattern of the double burden of obesity and hypertension in the elderly. Key risk factors are mainly diet-based, suggesting the importance of nutritional education of the elderly in Cameroon. Yet, large scale studies are needed to refine the nutritional education strategies for the elderly in Cameroon.
目的:探讨导致喀麦隆老年人肥胖和高血压双重负担的因素。方法:172名60岁以上的参与者参加了一项横断面研究,该研究在阜ban市的家庭中进行。每个参与者的社会人口学和营养数据是通过采用世界卫生组织STEP明智方法的问卷收集的,同时记录了人体测量和血液动力学测量。根据WHO指南和ACC/AHA定义,研究了肥胖和高血压双重负担的三种模式:i)全身性肥胖/高血压(GO/H), ii)腹部肥胖/高血压(AO/H)和iii)全身性和腹部肥胖/高血压合并(CO/H)。结果:不同类型肥胖和高血压双重负担的患病率分别为29.7% (CO/H)、37.8% (GO/H)和46.5% (AO/H)。婚姻类型、收入来源、脂肪和淀粉类食谱的消费、精制糖的消费和家族史与AO/H模式显著相关,而精制糖的消费和不规则水果消费与GO/H模式相关。结论:腹部肥胖是老年人肥胖和高血压双重负担中最常见的类型。关键的风险因素主要是基于饮食,这表明对喀麦隆老年人进行营养教育的重要性。然而,需要大规模的研究来完善喀麦隆老年人的营养教育策略。
{"title":"Double Burden of Obesity and Hypertension in the Elderly: Cross- Sectional Study of Prevalence and Risk Factors in Foumban, West Region, Cameroon","authors":"W. Dakam, P. Mintom, Chetou Mbete, Christine Fernande Nyangono Biyegue","doi":"10.26502/jfsnr.2642-110000105","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-110000105","url":null,"abstract":"Objective: To identify the factors contributing to the double burden of obesity and hypertension in the elderly Cameroonians. Methodology: A total of 172 participants aged over 60 were enrolled in a cross- sectional study carried out in households in the city of Foumban. The sociodemographic and nutritional data of each participant were collected using a questionnaire adapted from the WHO STEP wise approach while anthropometric and hemodynamic measurements were recorded. Based on the WHO guidelines and ACC/AHA definitions, three patterns of the double burden of obesity and hypertension were investigated: i) generalized obesity/hypertension (GO/H), ii) abdominal obesity/hypertension (AO/H) and iii) combined generalized and abdominal obesity/hypertension (CO/H). Results: Prevalence of the different patterns of the double burden of obesity and hypertension were: 29.7% (CO/H), 37.8% (GO/H), and 46.5% (AO/H). Type of marriage, source of income, consumption of fat and starchy recipes, consumption of refined sugars and family history were significantly linked to the AO/H pattern while consumption of refined sugars and irregular consumption of fruits were associated with the GO/H pattern. Conclusion: Abdominal obesity appears to be the most frequent pattern of the double burden of obesity and hypertension in the elderly. Key risk factors are mainly diet-based, suggesting the importance of nutritional education of the elderly in Cameroon. Yet, large scale studies are needed to refine the nutritional education strategies for the elderly in Cameroon.","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85411167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement of Body Image Flexibility in Adolescent Female Athletes Undergoing Education about Nutrition and Body Image 青少年女运动员营养与身体形象教育对身体形象柔韧性的改善
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-110000106
K. Vidlock, Catherine Liggett, Nicole Oberlag
Methods: A pre-post study was done measuring body image flexibility in adolescent female athletes. Athletes, aged 14-18, participated in educational sessions about nutrition, body image flexibility, and RED-S (relative energy deficiency in sport). Body image flexibility was measured by the BI-AAQ (Body Image - Acceptance and Action Questionnaire). Results: Increases were shown in all teams and overall. Specifically, mean BI-AAQ scores from 45.2 to 57.2 or difference of 12.0 (p-value <0.01). The cheer team showed an increase of the mean scores from 42.3 to 52.0 or difference of 9.7 (p-value 0.033). Overall scores improved from 43.6 to 54.1 or difference of 10.4 (p-value <0.01). Individual questions results shows that the cross country/track team had significant improvement in 8 of the 12 questions and the cheer team had significant improvement in 4 of the 12 questions. Discussion: This pre-post study examined the efficacy of three educational sessions during the athletic season. The positive outcomes in the short educational sessions suggest that starting education early may help with the mindset of positive body image flexibility at least short term. Conclusion: There was statistically significant short-term increase in body image flexibility in adolescent female athletes with education about body image, performance, and nutrition.
方法:对青少年女运动员身体形象柔韧性进行前后研究。14-18岁的运动员参加了关于营养、身体形象灵活性和RED-S(运动中相对能量不足)的教育课程。身体形象灵活性采用BI-AAQ(身体形象接受与行动问卷)进行测量。结果:所有团队和整体都有所增加。具体来说,BI-AAQ的平均得分从45.2到57.2,差异为12.0 (p值<0.01)。啦啦队的平均分从42.3分增加到52.0分,相差9.7分(p值为0.033)。总分从43.6分提高到54.1分,差异为10.4分(p值<0.01)。个别问题结果显示,越野队/田径队在12个问题中有8个问题有显著改善,啦啦队在12个问题中有4个问题有显著改善。讨论:这项前后研究考察了运动赛季期间三次教育课程的效果。短期教育课程的积极结果表明,尽早开始教育可能至少在短期内有助于培养积极的身体形象灵活性。结论:对青少年女运动员进行身体形象、成绩和营养方面的教育后,其身体形象柔韧性在短期内有统计学意义的提高。
{"title":"Improvement of Body Image Flexibility in Adolescent Female Athletes Undergoing Education about Nutrition and Body Image","authors":"K. Vidlock, Catherine Liggett, Nicole Oberlag","doi":"10.26502/jfsnr.2642-110000106","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-110000106","url":null,"abstract":"Methods: A pre-post study was done measuring body image flexibility in adolescent female athletes. Athletes, aged 14-18, participated in educational sessions about nutrition, body image flexibility, and RED-S (relative energy deficiency in sport). Body image flexibility was measured by the BI-AAQ (Body Image - Acceptance and Action Questionnaire). Results: Increases were shown in all teams and overall. Specifically, mean BI-AAQ scores from 45.2 to 57.2 or difference of 12.0 (p-value <0.01). The cheer team showed an increase of the mean scores from 42.3 to 52.0 or difference of 9.7 (p-value 0.033). Overall scores improved from 43.6 to 54.1 or difference of 10.4 (p-value <0.01). Individual questions results shows that the cross country/track team had significant improvement in 8 of the 12 questions and the cheer team had significant improvement in 4 of the 12 questions. Discussion: This pre-post study examined the efficacy of three educational sessions during the athletic season. The positive outcomes in the short educational sessions suggest that starting education early may help with the mindset of positive body image flexibility at least short term. Conclusion: There was statistically significant short-term increase in body image flexibility in adolescent female athletes with education about body image, performance, and nutrition.","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88679453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Ceftriaxone Residue in Cow Milk and its Toxicity on Danio rerio 牛奶中头孢曲松残留量及其对牛的毒性评价
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-110000119
J. Chowdhury, Riya Mukherjee, Debanjan Dutta, Tapan Kumar Mandal, T. Basu, Sandhimita Mondal
Ceftriaxone (CEFT), a widely used broad-spectrum beta -lactam cephalosporin antibiotic, is used to treat bovine mastitis, caused by a variety of bacteria. If used injudiciously, this antibiotic leaves a residue that persists after pasteurization. Antibiotic residue contamination occurs when antibiotic residue exceeds its Maximum Residue Limits (MRLs). This has negative impacts on both public health and the environment. The aim of a recent study was to determine the concentration of ceftriaxone residue (CEFTR) in raw and pasteurized mastitis cow milk, and its role in developmental toxicity and genotoxicity in the zebra fish model. The CEFTR concentrations in raw and pasteurized milk were several times higher than CEFT's MRL. CEFTR showed a decrease in body length and yolk sac region of zebra fish larvae 7-amino cephalosporanic acid (7-ACA), C3 and C7 are the cephalosporin components produced by the degradation of CEFT that may present in CEFTR, and have an impact on the zebra fish embryo in this stage of development. Comet Assay or Single Cell Gel Electrophoresis (SCGE) also exhibited highest percentage of tail DNA, and tail moment (DNA migration) that is the ultimate indicator of DNA damage by breaking DNA strands and incorporating guanine residue into the genome that ultimately damages the DNA. As a result, the CEFTR is extremely concerning for public health and the environment. The toxic effects of the CEFTR in zebra fish model have not yet been studied. This may be the first comprehensive study.
头孢曲松(cefaxone, CEFT)是一种广泛使用的广谱β -内酰胺类头孢菌素抗生素,用于治疗由多种细菌引起的牛乳腺炎。如果使用不当,这种抗生素在巴氏消毒后会留下残留。抗生素残留污染发生在抗生素残留超过其最大残留限量(MRLs)时。这对公众健康和环境都产生了负面影响。最近一项研究的目的是确定生乳腺炎牛奶和巴氏灭菌乳腺炎牛奶中头孢曲松残留物(CEFTR)的浓度,及其在斑马鱼模型中发育毒性和遗传毒性的作用。生奶和巴氏灭菌奶中的CEFTR浓度比CEFT的MRL高几倍。CEFTR降低了斑马鱼幼鱼体长和卵黄囊面积,7-氨基头孢菌酸(7-ACA)、C3和C7是CEFTR中可能存在的由CEFT降解产生的头孢菌素成分,对这一发育阶段的斑马鱼胚胎有影响。彗星试验或单细胞凝胶电泳(SCGE)也显示出最高百分比的尾部DNA和尾部力矩(DNA迁移),尾部力矩是DNA损伤的最终指标,DNA链断裂并将鸟嘌呤残基纳入基因组,最终损害DNA。因此,CEFTR对公共卫生和环境极为关切。CEFTR在斑马鱼模型中的毒性作用尚未得到研究。这可能是第一次全面的研究。
{"title":"Evaluation of Ceftriaxone Residue in Cow Milk and its Toxicity on Danio rerio","authors":"J. Chowdhury, Riya Mukherjee, Debanjan Dutta, Tapan Kumar Mandal, T. Basu, Sandhimita Mondal","doi":"10.26502/jfsnr.2642-110000119","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-110000119","url":null,"abstract":"Ceftriaxone (CEFT), a widely used broad-spectrum beta -lactam cephalosporin antibiotic, is used to treat bovine mastitis, caused by a variety of bacteria. If used injudiciously, this antibiotic leaves a residue that persists after pasteurization. Antibiotic residue contamination occurs when antibiotic residue exceeds its Maximum Residue Limits (MRLs). This has negative impacts on both public health and the environment. The aim of a recent study was to determine the concentration of ceftriaxone residue (CEFTR) in raw and pasteurized mastitis cow milk, and its role in developmental toxicity and genotoxicity in the zebra fish model. The CEFTR concentrations in raw and pasteurized milk were several times higher than CEFT's MRL. CEFTR showed a decrease in body length and yolk sac region of zebra fish larvae 7-amino cephalosporanic acid (7-ACA), C3 and C7 are the cephalosporin components produced by the degradation of CEFT that may present in CEFTR, and have an impact on the zebra fish embryo in this stage of development. Comet Assay or Single Cell Gel Electrophoresis (SCGE) also exhibited highest percentage of tail DNA, and tail moment (DNA migration) that is the ultimate indicator of DNA damage by breaking DNA strands and incorporating guanine residue into the genome that ultimately damages the DNA. As a result, the CEFTR is extremely concerning for public health and the environment. The toxic effects of the CEFTR in zebra fish model have not yet been studied. This may be the first comprehensive study.","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"136 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76381728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Consumption of Convenience Store Food and Obesity in Urban Preschool-going Children: A Cross-Sectional study in Nepal 尼泊尔城市学龄前儿童便利店食品消费与肥胖:一项横断面研究
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-11000095
Parvez Ahmed, Alisha Bohora, Nawzia Yasmin, N. Alam, Mahim Eaty
Background Childhood obesity is a complex condition and the associated factors are not well understood. This paper aims to explore the relationship of behavioral factors including consumption of convenience stores food for lunch at school and obesity in urban preschool-going children. A cross-sectional study was conducted among 351 selected children The Organization was used to categorize children into underweight, normal, and obese according to age and sex. Multinomial logistic regression analysis was conducted to assess the association. The findings suggest that consumption of convenience store food for lunch at school is associated with obesity in urban preschool-going children in Nepal. The findings can help to explain the information and knowledge gaps regarding obesity in preschool-going children in Nepal.
儿童肥胖是一种复杂的疾病,其相关因素尚不清楚。本文旨在探讨城市学龄前儿童在学校午餐食用便利店食品等行为因素与肥胖的关系。在351名儿童中进行了一项横断面研究,该组织根据年龄和性别将儿童分为体重不足、正常和肥胖。采用多项逻辑回归分析来评估相关性。研究结果表明,尼泊尔城市学龄前儿童在学校午餐时食用便利店食品与肥胖有关。这些发现可以帮助解释尼泊尔学龄前儿童肥胖方面的信息和知识差距。
{"title":"Consumption of Convenience Store Food and Obesity in Urban Preschool-going Children: A Cross-Sectional study in Nepal","authors":"Parvez Ahmed, Alisha Bohora, Nawzia Yasmin, N. Alam, Mahim Eaty","doi":"10.26502/jfsnr.2642-11000095","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-11000095","url":null,"abstract":"Background Childhood obesity is a complex condition and the associated factors are not well understood. This paper aims to explore the relationship of behavioral factors including consumption of convenience stores food for lunch at school and obesity in urban preschool-going children. A cross-sectional study was conducted among 351 selected children The Organization was used to categorize children into underweight, normal, and obese according to age and sex. Multinomial logistic regression analysis was conducted to assess the association. The findings suggest that consumption of convenience store food for lunch at school is associated with obesity in urban preschool-going children in Nepal. The findings can help to explain the information and knowledge gaps regarding obesity in preschool-going children in Nepal.","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"114 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90907609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global Association of Obesity and COVID-19 Death Rates 全球肥胖与COVID-19死亡率的关联
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-110000112
Mary Adams
{"title":"Global Association of Obesity and COVID-19 Death Rates","authors":"Mary Adams","doi":"10.26502/jfsnr.2642-110000112","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-110000112","url":null,"abstract":"","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75000563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Correlation Between Phase Angle and Nutritional Status in Hospitalized Patients at Nutritional Risk 有营养风险住院患者的相位角与营养状况的关系
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-110000121
Ludiane Alves do Nascimento, J. Carvalho, Grasiela Konkolisc Pina de Andrade, A. Severine, Ana Lucia Chalhoub Chediac Rodrigues.
Background & Aims: This study evaluated the correlations between phase angle (PA) and muscle mass (MM), which can contribute to an accurate nutritional diagnosis. Methods: Retrospective cross-sectional study, conducted from July 2020 to July 2021, included patients classified as at-risk based on their initial nutritional assessments. Bioelectrical impedance analysis was used to evaluate body composition and determine the phase angle (PA). Data on nutritional status and hospital stay were also obtained. Results: Among the 1.012 evaluated patients, 55% (557) were male, the median age was 71.8 years, and the median body mass index (BMI) was 22.7 kg/m 2 . A total of 60.1% (606) of the patients had low MM. The PA cut-off for reduced MM was 4.30º for the total population and for men, and 3.76º for women. Patients with reduced PA were older (61.8 [23] vs. 76.4 [19] years; p<0.001), had a longer hospital stay (14 [20] vs. 11[15]; p<0.001) and lower BMI (24.1 [6.0] vs 22.3 [4.8] kg/m 2 ; p<0.001). Patients with a hospital stay >11 days were twice as likely to have a reduced PA (odds ratio [OR] = 2.00, 95% confidence interval [CI] 1.37–2.93). In addition, patients from critical units were almost twice as likely to have a reduced PA (OR = 1.87, 95% CI 1.22–2.87). Conclusion: Patients with reduced MM presented a lower PA cut-off than that for patients with normal MM; thus, the PA represents a good marker to detect MM reduction. A reduced PA also increased the likelihood of malnutrition and prolonged hospital stay.
背景与目的:本研究评估相位角(PA)与肌肉质量(MM)的相关性,有助于准确的营养诊断。方法:回顾性横断面研究,于2020年7月至2021年7月进行,纳入根据初始营养评估分类为高危的患者。采用生物电阻抗分析评价体成分,确定相位角(PA)。还获得了营养状况和住院时间的数据。结果:1.012例患者中,55%(557例)为男性,中位年龄71.8岁,中位体重指数(BMI)为22.7 kg/ m2。共有60.1%(606)的患者有低MM。MM降低的PA临界值在总人口和男性中为4.30º,在女性中为3.76º。PA减少的患者年龄较大(61.8[23]对76.4[19]岁;p11天出现PA降低的可能性为2倍(优势比[OR] = 2.00, 95%可信区间[CI] 1.37-2.93)。此外,危重病房的患者PA降低的可能性几乎是其两倍(OR = 1.87, 95% CI 1.22-2.87)。结论:MM减少患者的PA截止值低于MM正常患者;因此,PA是检测MM减少的良好标记。PA降低也增加了营养不良和住院时间延长的可能性。
{"title":"Correlation Between Phase Angle and Nutritional Status in Hospitalized Patients at Nutritional Risk","authors":"Ludiane Alves do Nascimento, J. Carvalho, Grasiela Konkolisc Pina de Andrade, A. Severine, Ana Lucia Chalhoub Chediac Rodrigues.","doi":"10.26502/jfsnr.2642-110000121","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-110000121","url":null,"abstract":"Background & Aims: This study evaluated the correlations between phase angle (PA) and muscle mass (MM), which can contribute to an accurate nutritional diagnosis. Methods: Retrospective cross-sectional study, conducted from July 2020 to July 2021, included patients classified as at-risk based on their initial nutritional assessments. Bioelectrical impedance analysis was used to evaluate body composition and determine the phase angle (PA). Data on nutritional status and hospital stay were also obtained. Results: Among the 1.012 evaluated patients, 55% (557) were male, the median age was 71.8 years, and the median body mass index (BMI) was 22.7 kg/m 2 . A total of 60.1% (606) of the patients had low MM. The PA cut-off for reduced MM was 4.30º for the total population and for men, and 3.76º for women. Patients with reduced PA were older (61.8 [23] vs. 76.4 [19] years; p<0.001), had a longer hospital stay (14 [20] vs. 11[15]; p<0.001) and lower BMI (24.1 [6.0] vs 22.3 [4.8] kg/m 2 ; p<0.001). Patients with a hospital stay >11 days were twice as likely to have a reduced PA (odds ratio [OR] = 2.00, 95% confidence interval [CI] 1.37–2.93). In addition, patients from critical units were almost twice as likely to have a reduced PA (OR = 1.87, 95% CI 1.22–2.87). Conclusion: Patients with reduced MM presented a lower PA cut-off than that for patients with normal MM; thus, the PA represents a good marker to detect MM reduction. A reduced PA also increased the likelihood of malnutrition and prolonged hospital stay.","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87904406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement on BAF53B Mutation Caused Developmental and Epileptic Encephalopathy with a Ketogenic Diet 生酮饮食改善BAF53B突变引起的发育性和癫痫性脑病
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-110000118
Danli Wang, Linlin Fan, Haoying Yang, Mingming Pan, Junping Shi, Ang Li, Nini Wang, Xue Xia, Yang Liu
Purpose: Genetic mutation is the leading cause of Developmental and Epileptic Encephalopathy (DEE, OMIM 308350), a spectrum of disorders characterized by severe epilepsy and usually begins in infancy, accompanied with psychomotor development arrest and hypsarrhythmiaon electroencephalogram (EEG).Up till now, mutations of 101 genes were confirmed as the cause of DEE, and were categorized accordingly into 101 different sub-types (DEE1-101). Here, we report a case of DEE76 with a tortuous path to genetic diagnosis and an illuminating treatment of ketogenic diet (KD). Methods: Through high throughput sequencing, we identified a DEE76 case caused by biallelic BAF53B mutation inherited in an autosomal recessive manner, and report the pathogenic variants NM_016188.4:c.892C>T (p.Arg298*) and NM_016188.4:c.991_996delinsAA (p.Gly331Asnfs*44) for the first time. Results: The proband commenced seizures on day five after birth and rapidly deteriorated during development. After a series of therapeutic exploration, ketogenic diet turned out to be the most hopeful treatment available. Conclusion: ultra-rare gene therapy KD, seizures
目的:基因突变是发育性和癫痫性脑病(DEE, OMIM 308350)的主要原因。发育性和癫痫性脑病是一种以严重癫痫为特征的疾病,通常始于婴儿期,伴有精神运动发育停止和低心律失常脑电图(EEG)。到目前为止,有101个基因突变被确认为DEE的病因,并据此分为101个不同的亚型(DEE1-101)。在这里,我们报告一个病例DEE76曲折的路径遗传诊断和启发性的治疗生酮饮食(KD)。方法:通过高通量测序,鉴定1例由常染色体隐性遗传的双等位基因BAF53B突变引起的DEE76病例,并报道致病变异NM_016188.4:c。c. 892C>T (p.Arg298*)和NM_016188.4;991_996delinsAA (p.Gly331Asnfs*44)。结果:先证者在出生后第5天开始癫痫发作,在发育过程中病情迅速恶化。经过一系列的治疗探索,生酮饮食被证明是最有希望的治疗方法。结论:超罕见基因治疗KD,癫痫发作
{"title":"Improvement on BAF53B Mutation Caused Developmental and Epileptic Encephalopathy with a Ketogenic Diet","authors":"Danli Wang, Linlin Fan, Haoying Yang, Mingming Pan, Junping Shi, Ang Li, Nini Wang, Xue Xia, Yang Liu","doi":"10.26502/jfsnr.2642-110000118","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-110000118","url":null,"abstract":"Purpose: Genetic mutation is the leading cause of Developmental and Epileptic Encephalopathy (DEE, OMIM 308350), a spectrum of disorders characterized by severe epilepsy and usually begins in infancy, accompanied with psychomotor development arrest and hypsarrhythmiaon electroencephalogram (EEG).Up till now, mutations of 101 genes were confirmed as the cause of DEE, and were categorized accordingly into 101 different sub-types (DEE1-101). Here, we report a case of DEE76 with a tortuous path to genetic diagnosis and an illuminating treatment of ketogenic diet (KD). Methods: Through high throughput sequencing, we identified a DEE76 case caused by biallelic BAF53B mutation inherited in an autosomal recessive manner, and report the pathogenic variants NM_016188.4:c.892C>T (p.Arg298*) and NM_016188.4:c.991_996delinsAA (p.Gly331Asnfs*44) for the first time. Results: The proband commenced seizures on day five after birth and rapidly deteriorated during development. After a series of therapeutic exploration, ketogenic diet turned out to be the most hopeful treatment available. Conclusion: ultra-rare gene therapy KD, seizures","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"205 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75864566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correlation Between Staple Diet and its Effect on Physical Aesthetics Depicted in Paintings, Sculptures and Figurines: Greek v/s. Indian Culture 绘画、雕塑和小雕像中主食饮食对身体美学的影响:希腊v/s。印度文化
Pub Date : 2022-01-01 DOI: 10.26502/jfsnr.2642-11000092
A. Dhawan, Jeeja Hernole
Correlation Between Staple Diet and its Effect on Physical Aesthetics Depicted in Paintings, Sculptures and Figurines: Greek v/s. Indian Culture. Abstract In the specific cultural setting, the need to find links between multimodal aspects and their interconnection like regional food and regional art is necessary. The regional socio-cultural aspects such as food greatly influence human beings' physical appearances, which may be depicted in art forms. Different cultures have existed for centuries. Each culture had its unique cuisines, art, peculiar traditions, geographic location, and many prominent features which identify that specific culture distinctively. Up to some extent, cuisine and staple food plays a vital role in the culture. This review-based research focuses on finding out the prevalence of staple food and specific culture nutrition on shaping its art forms. Also, how the staple diet and daily activity of people from particular cultures shaped their physical aesthetics and how these physical aesthetics are depicted in paintings or sculptures. Hence, the article's significance is to find if any pattern exists between staple diet and art from across different cultures, i.e., for instance, compared to ancient European (Greek) and Indian culture.
绘画、雕塑和小雕像中主食饮食对身体美学的影响:希腊v/s。印度文化。在特定的文化背景下,像地域饮食和地域艺术一样,寻找多式联运方面之间的联系和相互联系是必要的。区域社会文化方面,如食物,极大地影响了人类的外表,这可以用艺术形式来描绘。不同的文化已经存在了几个世纪。每种文化都有其独特的烹饪、艺术、独特的传统、地理位置和许多突出的特征,这些特征使这种特定的文化与众不同。在某种程度上,烹饪和主食在文化中起着至关重要的作用。本文的研究重点是找出主食的流行程度及其艺术形式形成的特定文化营养。此外,来自特定文化的人们的主要饮食和日常活动如何塑造他们的身体美学,以及这些身体美学如何在绘画或雕塑中被描绘出来。因此,这篇文章的意义在于发现主食与不同文化的艺术之间是否存在某种模式,例如,与古代欧洲(希腊)和印度文化相比。
{"title":"Correlation Between Staple Diet and its Effect on Physical Aesthetics Depicted in Paintings, Sculptures and Figurines: Greek v/s. Indian Culture","authors":"A. Dhawan, Jeeja Hernole","doi":"10.26502/jfsnr.2642-11000092","DOIUrl":"https://doi.org/10.26502/jfsnr.2642-11000092","url":null,"abstract":"Correlation Between Staple Diet and its Effect on Physical Aesthetics Depicted in Paintings, Sculptures and Figurines: Greek v/s. Indian Culture. Abstract In the specific cultural setting, the need to find links between multimodal aspects and their interconnection like regional food and regional art is necessary. The regional socio-cultural aspects such as food greatly influence human beings' physical appearances, which may be depicted in art forms. Different cultures have existed for centuries. Each culture had its unique cuisines, art, peculiar traditions, geographic location, and many prominent features which identify that specific culture distinctively. Up to some extent, cuisine and staple food plays a vital role in the culture. This review-based research focuses on finding out the prevalence of staple food and specific culture nutrition on shaping its art forms. Also, how the staple diet and daily activity of people from particular cultures shaped their physical aesthetics and how these physical aesthetics are depicted in paintings or sculptures. Hence, the article's significance is to find if any pattern exists between staple diet and art from across different cultures, i.e., for instance, compared to ancient European (Greek) and Indian culture.","PeriodicalId":15858,"journal":{"name":"Journal of Food Science and Nutrition Research","volume":"357 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78955004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Food Science and Nutrition Research
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1