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Methodological progress note: Pilot randomized controlled trials 方法进展说明:试点随机对照试验。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-24 DOI: 10.1002/jhm.13376
Amanda Corley RN PhD, Nicole Marsh RN PhD, Samantha Keogh RN PhD
<p>Definitive randomized controlled trials (RCTs) are the cornerstone of evidence-based medicine but can be complicated, protracted, and expensive. Given the challenges of large-scale trials, pilot trials serve as a crucial initial step, allowing for refinement and validation before embarking on the definitive RCT.<span><sup>1</sup></span> They are a crucial element of good study design and, while conducting a pilot RCT does not guarantee success of the definitive RCT, it increases the likelihood of successful trial completion.<span><sup>2</sup></span> More than US$100 billion is invested annually in biomedical research but often this research is conducted wastefully from poor study design and/or study procedures.<span><sup>3</sup></span> Conducting a well-designed pilot RCT before launching an expensive, time-consuming definitive trial can minimize research waste and improve study conduct.</p><p>Small RCTs cannot be branded pilot or feasibility trials to justify a small sample size. Pilot RCTs have a very specific purpose and inform future trial conduct.<span><sup>4</sup></span> Indeed, research models, including the Canadian Critical Care Trials Group programmatic model, the UK Medical Research Council, and the Australian Clinical Trials Alliance, highlight the importance of pilot RCTs as an integral and necessary step in interventional clinical research (Figure 1). Early piloting of research methods and interventions is important in evaluating feasibility and acceptability before the definitive RCT.</p><p>The importance of pilot trials has been acknowledged for decades<span><sup>5</sup></span> with trial methods evolving over time. It is within this context that we will discuss pilot RCTs used to inform larger definitive RCTs. We will situate pilot trial methods within a larger research framework and propose important concepts in design and reporting.</p><p>The terms “pilot” and “feasibility” trial are used interchangeably by some, but others purport that each type of trial has unique characteristics and therefore define them separately. Whitehead et al.<span><sup>4</sup></span> proposed that pilot trials are a type of feasibility trial with some distinguishing elements: (i) stricter methodology (closely following the definitive study design); (ii) intended to lead to further work; (iii) a smaller version of the larger study; and (iv) focuses on trial processes. This delineation suggests that a pilot RCT is a specific subset of feasibility trial. Henceforth, we adopt the term “pilot.”</p><p>Pilot RCTs allow researchers to test and establish feasibility of the study protocol, study processes, data collection, and intervention fidelity and acceptability.<span><sup>2, 4, 6</sup></span> Table 1 details trial elements tested by a pilot RCT.</p><p>An important indicator of trial feasibility is the ability to recruit the required numbers of participants, using inclusion/exclusion criteria, from the sample population. Recruitment to RCTs can be challe
确定性随机对照试验(RCT)是循证医学的基石,但可能会很复杂、旷日持久且费用高昂。1 试点试验是良好研究设计的关键要素,虽然进行试点试验并不能保证最终 RCT 的成功,但却能增加试验成功完成的可能性。每年用于生物医学研究的投资超过 1000 亿美元,但这些研究往往因研究设计和/或研究程序不当而造成浪费。3 在启动昂贵、耗时的最终试验之前,进行精心设计的试验性 RCT 可以最大限度地减少研究浪费,改善研究行为。4 事实上,包括加拿大重症监护试验小组计划模式、英国医学研究委员会和澳大利亚临床试验联盟在内的各种研究模式都强调了试验性 RCT 的重要性,认为它是干预性临床研究不可或缺的必要步骤(图 1)。研究方法和干预措施的早期试点对于在最终 RCT 之前评估可行性和可接受性非常重要。几十年来,随着试验方法的不断发展,试点试验的重要性已得到认可5。正是在这种背景下,我们将讨论用于为更大规模的确定性研究试验提供信息的试验性研究试验。我们将把先导试验方法置于更大的研究框架中,并提出设计和报告方面的重要概念。"先导 "和 "可行性 "试验这两个术语在一些人那里可以互换使用,但另一些人则认为每种类型的试验都有其独特性,因此要分别定义。怀特黑德等人4 提出,试验性试验是可行性试验的一种,具有一些区别要素:(i) 采用更严格的方法(严格遵循确定的研究设计);(ii) 旨在开展进一步的工作;(iii) 是大型研究的缩小版;(iv) 侧重于试验过程。这种划分表明,试验性 RCT 是可行性试验的一个特定子集。因此,我们采用 "试验 "一词。试验性 RCT 使研究人员能够测试和确定研究方案、研究过程、数据收集以及干预的忠实性和可接受性的可行性。6 研究者过高估计样本群的规模,最终导致招募不足,使试验无法回答提出的研究问题,浪费资源,而且可能不符合伦理道德,这往往是放弃严格的试点试验过程的结果。资助者也重视在开展确定性 RCT 之前测试可行性的重要性。例如,在澳大利亚国家健康与医学研究委员会的标准中,研究项目必须 "在所有必要的技术和资源都已确定的情况下,具有高度可行性"。外部试点 RCT 是在最终 RCT 之前完成的独立试验:对数据进行分析,得出结果,从而为推进最终试验的可行性提供信息。如果干预措施的忠实性或新的试验内容(如新的临床环境)存在不确定性,外部试点 RCT 尤为有用。8 但是,外部试点 RCT 的数据不包括在大型试验中,而是单独公布,因此可能被视为 "浪费"。"4 此外,外部试验性 RCT 可能很难吸引到资金,尤其是当研究结果与患者获益无关,而是侧重于可行性时。9 Cooper 等人认为,当总体可行性已基本确定,但需要有关招募、随机化和自然减员率的证据时,这种方法非常有用。10 内部试点 RCT 是最终 RCT 的一个阶段,计划与主要试验同时进行。明确的预设进展标准(见下节)用于决定是否进入最终 RCT,9 最好由外部专家小组做出决定。
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引用次数: 0
Artificial intelligence, ethics, and hospital medicine: Addressing challenges to ethical norms and patient-centered care 人工智能、伦理和医院医疗:应对伦理规范和以患者为中心的护理所面临的挑战。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-22 DOI: 10.1002/jhm.13364
Micah Prochaska MD, MSc, David Alfandre MD, MPH

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引用次数: 0
Innovations Corner: A new column in the Journal of Hospital Medicine 创新角:医院医学杂志》的新专栏。
IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-22 DOI: 10.1002/jhm.13369
Suchita S. Sata MD, FACP, SFHM, Samir S. Shah MD, MSCE, MHM
<p>The <i>Journal of Hospital Medicine</i> (JHM) is dedicated to advancing the practice and science of inpatient medicine. As part of our commitment to supporting hospitalists in their pursuit of excellence, we proudly introduce Innovations Corner, a new article type in the journal. We designed Innovations Corner to provide a forum to share inventive solutions to vexing problems encountered by clinicians or patients in the inpatient setting. These short reports are structured to highlight the innovation and its impact and to provide readers with tools to accelerate change in their institutions (Table 1).</p><p>Hospitalists innovate locally and transform globally. JHM's Innovations Corner celebrates the ingenuity of hospitalists while serving as a platform for scalability and shared innovation. Reports in Innovations Corner describe care improvement interventions, emphasizing the process of progress. We welcome submissions that address common challenges for patients, teams, and institutions. We seek reports on innovations in any aspect of care delivery that have the potential for adaptation or scalability. We anticipate that published articles will use a wide array of methodological approaches and apply them to the quotidian issues that arise during the provision of care. Topics of particular interest include common systems challenges that affect patients or clinicians, resource stewardship, patient safety measures, and innovative care pathways. Submissions showcasing interdisciplinary teams or patient involvement are encouraged.</p><p>In this issue,<span><sup>1</sup></span> Sanders et al. describe their efforts to improve inpatient glycemic control through a multifaceted intervention. Their sustained and safe improvement methods can be adopted by other institutions.</p><p>Each article will also be accompanied by a graphical summary, “Driving Change: Keys to Innovation.” This summary visually communicates key components of the innovation and was designed for sharing with administrative stakeholders. This section of Innovations Corner prioritizes readability and visual appeal to convey the salient messages. We understand that frontline clinicians need to communicate succinctly and effectively about complex problems with those who may lack medical training or a nuanced understanding of the care system. In titling this graphical summary, “Driving Change: Keys to Innovation,” we signal that hospitalists are in the driver's seat, accelerating improvement and paving a path of progress.</p><p>Sharing these innovations allows hospitalists to leverage peer wisdom to improve patient care, enhance outcomes, and make meaningful advancements in the field. We seek to foster collaboration and knowledge-sharing among inpatient clinicians to help them work smarter, build upon successes, reduce redundancies, and ensure that the wheel of innovation turns towards benefiting patients, healthcare providers, and the entire healthcare system.</p><p>The authors declare no
医院医学杂志》(JHM)致力于推动住院医疗的实践和科学发展。作为我们支持住院医生追求卓越的承诺的一部分,我们隆重推出《创新园地》这一期刊的新文章类型。我们设计 "创新园地 "的目的是提供一个论坛,分享临床医生或患者在住院环境中遇到的棘手问题的创新解决方案。这些简短的报告结构突出了创新及其影响,并为读者提供了加快其所在机构变革的工具(表 1)。JHM 的 "创新园地 "弘扬了医院医生的聪明才智,同时也为可扩展性和共享创新提供了一个平台。创新角的报告描述了护理改进措施,强调了进步的过程。我们欢迎针对患者、团队和机构面临的共同挑战提交报告。我们征集有关护理服务任何方面的创新报告,这些创新都具有适应性和可扩展性。我们希望发表的文章能够采用多种方法,并将其应用于医疗服务过程中出现的日常问题。我们特别关注的主题包括影响患者或临床医生的常见系统挑战、资源管理、患者安全措施和创新护理路径。本期1 中,桑德斯等人介绍了他们通过多方面干预改善住院患者血糖控制的工作。他们持续、安全的改进方法可供其他机构借鉴。每篇文章还将附有图表摘要 "推动变革:创新的关键"。该摘要直观地传达了创新的关键要素,旨在与行政利益相关者分享。创新角 "的这一部分将优先考虑可读性和视觉吸引力,以传达突出的信息。我们深知,一线临床医生需要就复杂的问题与那些可能缺乏医学培训或对医疗系统缺乏细致了解的人进行简洁有效的沟通。我们将本图表摘要命名为 "推动变革:通过分享这些创新成果,医院医生可以利用同行的智慧来改善患者护理、提高疗效,并在该领域取得有意义的进步。我们力求促进住院临床医生之间的合作和知识共享,帮助他们更聪明地工作,在成功的基础上再接再厉,减少冗余,确保创新之轮转动起来,造福患者、医疗服务提供者和整个医疗保健系统。
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引用次数: 0
Changing patterns of routine laboratory testing over time at children's hospitals 儿童医院常规实验室检测模式的长期变化
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-21 DOI: 10.1002/jhm.13372
Michael J. Tchou MD, MSc, Matt Hall PhD, Jessica L. Markham MD, MSc, John R. Stephens MD, Michael J. Steiner MD, MPH, Elisha McCoy MD, Paul L. Aronson MD, MHS, Samir S. Shah MD, MSCE, Matthew J. Molloy MD, MPH, Jillian M. Cotter MD, MSCS

Background

Research into low-value routine testing at children's hospitals has not consistently evaluated changing patterns of testing over time.

Objectives

To identify changes in routine laboratory testing rates at children's hospitals over ten years and the association with patient outcomes.

Design, Settings, and Participants

We performed a multi-center, retrospective cohort study of children aged 0–18 hospitalized with common, lower-severity diagnoses at 28 children's hospitals in the Pediatric Health Information Systems database.

Main Outcomes and Measures

We calculated average annual testing rates for complete blood counts, electrolytes, and inflammatory markers between 2010 and 2019 for each hospital. A >2% average testing rate change per year was defined as clinically meaningful and used to separate hospitals into groups: increasing, decreasing, and unchanged testing rates. Groups were compared for differences in length of stay, cost, and 30-day readmission or ED revisit, adjusted for demographics and case mix index.

Results

Our study included 576,572 encounters for common, low-severity diagnoses. Individual hospital testing rates in each year of the study varied from 0.3 to 1.4 tests per patient day. The average yearly change in hospital-specific testing rates ranged from –6% to +7%. Four hospitals remained in the lowest quartile of testing and two in the highest quartile throughout all 10 years of the study. We grouped hospitals with increasing (8), decreasing (n = 5), and unchanged (n = 15) testing rates. No difference was found across subgroups in costs, length of stay, 30-day ED revisit, or readmission rates. Comparing resource utilization trends over time provides important insights into achievable rates of testing reduction.

背景对儿童医院低价值常规检验的研究并未持续评估检验模式随时间推移而发生的变化。设计、设置和参与者我们对儿科健康信息系统数据库中28家儿童医院的0-18岁住院患儿进行了一项多中心、回顾性队列研究,这些患儿均患有常见的、较低程度的诊断。每年 2% 的平均检测率变化被定义为具有临床意义,并将医院分为三组:检测率上升组、下降组和保持不变组。经人口统计学和病例组合指数调整后,比较各组在住院时间、成本、30 天再入院或急诊室复诊方面的差异。在研究的每一年中,每家医院对每位患者每天的检测率从 0.3 到 1.4 不等。医院检测率的年均变化范围为 -6% 到 +7%。在整个研究的十年中,有四家医院的检测率一直处于最低四分位数,两家医院处于最高四分位数。我们对检测率上升(8 家)、下降(5 家)和保持不变(15 家)的医院进行了分组。各分组在费用、住院时间、30 天急诊室复诊率或再入院率方面均无差异。通过比较不同时期的资源利用趋势,可以深入了解降低检测率的可行性。
{"title":"Changing patterns of routine laboratory testing over time at children's hospitals","authors":"Michael J. Tchou MD, MSc,&nbsp;Matt Hall PhD,&nbsp;Jessica L. Markham MD, MSc,&nbsp;John R. Stephens MD,&nbsp;Michael J. Steiner MD, MPH,&nbsp;Elisha McCoy MD,&nbsp;Paul L. Aronson MD, MHS,&nbsp;Samir S. Shah MD, MSCE,&nbsp;Matthew J. Molloy MD, MPH,&nbsp;Jillian M. Cotter MD, MSCS","doi":"10.1002/jhm.13372","DOIUrl":"10.1002/jhm.13372","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Research into low-value routine testing at children's hospitals has not consistently evaluated changing patterns of testing over time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To identify changes in routine laboratory testing rates at children's hospitals over ten years and the association with patient outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Design, Settings, and Participants</h3>\u0000 \u0000 <p>We performed a multi-center, retrospective cohort study of children aged 0–18 hospitalized with common, lower-severity diagnoses at 28 children's hospitals in the Pediatric Health Information Systems database.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main Outcomes and Measures</h3>\u0000 \u0000 <p>We calculated average annual testing rates for complete blood counts, electrolytes, and inflammatory markers between 2010 and 2019 for each hospital. A &gt;2% average testing rate change per year was defined as clinically meaningful and used to separate hospitals into groups: increasing, decreasing, and unchanged testing rates. Groups were compared for differences in length of stay, cost, and 30-day readmission or ED revisit, adjusted for demographics and case mix index.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Our study included 576,572 encounters for common, low-severity diagnoses. Individual hospital testing rates in each year of the study varied from 0.3 to 1.4 tests per patient day. The average yearly change in hospital-specific testing rates ranged from –6% to +7%. Four hospitals remained in the lowest quartile of testing and two in the highest quartile throughout all 10 years of the study. We grouped hospitals with increasing (8), decreasing (<i>n</i> = 5), and unchanged (<i>n</i> = 15) testing rates. No difference was found across subgroups in costs, length of stay, 30-day ED revisit, or readmission rates. Comparing resource utilization trends over time provides important insights into achievable rates of testing reduction.</p>\u0000 </section>\u0000 </div>","PeriodicalId":15883,"journal":{"name":"Journal of hospital medicine","volume":"19 8","pages":"671-679"},"PeriodicalIF":2.4,"publicationDate":"2024-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140635062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence in medicine: A primer and recommendation 人工智能在医学中的应用:入门指南和建议
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-19 DOI: 10.1002/jhm.13371
Shitij Arora MD, Sunit P. Jariwala MD, Satchit Balsari MD, MPH

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引用次数: 0
The development and pilot of a novel mobile application to assess clinician perception of workload and work environment 开发和试用新型移动应用程序,评估临床医生对工作量和工作环境的感知
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-18 DOI: 10.1002/jhm.13366
Marisha Burden MD, MBA, Lauren McBeth BA, Angela Keniston PhD, MSPH

Background

Traditional measures of workload such as wRVUs may not be adequate to understand the impact of workload on key outcomes.

Objective

The objective of this study was to develop a mobile application to assess, in near real time, clinicians' perception of workload and work environment.

Designs, Settings and Participants

We developed the GrittyWork™ application (GW App) using the Chokshi and Mann process model for user-centered digital development. Study occured at a single academic medical center with hospitalist clinicians.

Main Outcome Measures and Measures

Measures included the System Usability Scale (SUS), use measures from GW App, electronic health record (EHR) event log data and note counts, and qualitative interviews.

Results

From October 28, 2022 to November 3, 2022, six hospitalist clinicians provided feedback on the early prototype of the GW App, and from February 28, 2023 to June 8, 2023, 30 hospitalist clinicians participated in the pilot while on clinical service. All 30 clinicians (100%) participated in the pilot submitting data for a total of 122 shifts. Participants reported working 10 ± 1 h per day (mean ± SD) and were responsible for an average of 11 ± 3 patients per day. The postpilot evaluation of the GW App showed a SUS score of 86 ± 11 and a participant preference toward mobile application-based surveys (73% of participants). Regarding workload measures, EHR event log data and notes data correlated with physician-reported workloads. Applying user-centered design techniques, we successfully developed a mobile application with high usability. These data can be paired with EHR event log data and outcomes to provide insights into the impact of workloads and work environments on outcomes.

背景传统的工作量测量方法(如 wRVUs)可能不足以了解工作量对关键结果的影响。目标本研究的目标是开发一款移动应用程序,以近乎实时的方式评估临床医生对工作量和工作环境的感知。设计、设置和参与者我们采用 Chokshi 和 Mann 流程模型开发了 GrittyWork™ 应用程序(GW App),以用户为中心进行数字开发。结果2022年10月28日至2022年11月3日,6名医院临床医生对GW应用的早期原型提供了反馈意见;2023年2月28日至2023年6月8日,30名医院临床医生在临床服务期间参与了试点。所有 30 名临床医生(100%)都参与了试点工作,共提交了 122 个班次的数据。参与者表示每天工作 10 ± 1 小时(平均 ± SD),平均每天负责 11 ± 3 名患者。对 GW 应用程序的试点后评估显示,SUS 得分为 86 ± 11,参与者偏好基于移动应用程序的调查(73% 的参与者)。在工作量测量方面,电子病历事件日志数据和笔记数据与医生报告的工作量相关。应用以用户为中心的设计技术,我们成功开发出了一款可用性极高的移动应用程序。这些数据可与电子病历事件日志数据和结果配对使用,以便深入了解工作量和工作环境对结果的影响。
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引用次数: 0
Modern art 现代艺术
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-17 DOI: 10.1002/jhm.13342
Michelle Izmaylov MD
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引用次数: 0
Transitional care clinics for patients discharged from hospital without a primary care provider: A systematic review 为没有初级保健提供者的出院患者开设过渡护理诊所:系统回顾
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-16 DOI: 10.1002/jhm.13359
Cait Dmitriew MD, PhD, Del J. Houle MA, Michelle Filipovic MD, Ella Chochla MD, Alexander Hemy MD, Celeste Woods MSc, MD, Nawal Farhat MSc, PhD, Alanna Campbell MISt, Lisa J. W. Liu MPH, Jacquelyn J. Cragg MPH, PhD, James A. G. Crispo MSc, PhD

Background

The transition from hospital to home is a high-risk period. Timely follow-up care is essential to reducing avoidable harms such as adverse drug events, yet may be unattainable for patients who lack attachment to a primary care provider. Transitional care clinics (TCCs) have been proposed as a measure to improve health outcomes for patients discharged from hospital without an established provider. In this systematic review, we compared outcomes for unattached patients seen in TCCs after hospital discharge relative to care as usual.

Methods

We searched the following bibliographic databases for articles published on or before August 12, 2022: MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Cochrane Database of Systematic Reviews, PsycINFO, and Web of Science. Five studies were identified that examined the effects of a dedicated postdischarge clinic on emergency department (ED) visits, readmissions, and/or mortality within 90 days of discharge for patients with no attachment to a primary care provider.

Results

Studies were heterogeneous in design and quality; all were from urban centers within the United States. Four of the five studies reported a reduction in either the number of ED visits or readmissions in patients seen in a TCC following hospitalization.

Conclusions

TCCs may be effective in reducing hospital contacts in the period following hospital discharge in patients with no established primary care provider. Further studies are required to evaluate the health benefits attributable to the implementation of TCCs across a broad range of practice contexts, as well as the cost implications of this model.

从医院到家庭的过渡是一个高风险时期。及时的后续护理对于减少药物不良反应等可避免的伤害至关重要,但对于缺乏初级医疗服务提供者的患者来说,这可能是无法实现的。过渡护理诊所(TCCs)被认为是改善没有固定医疗服务提供者的出院患者健康状况的一种措施。在这篇系统性综述中,我们比较了出院后在过渡护理诊所就诊的无依附性患者的治疗效果与常规护理的效果。
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引用次数: 0
Hospitalizations and transgender patients in the United States 美国变性患者的住院情况
IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-16 DOI: 10.1002/jhm.13368
Keshav Khanijow MD, Scott Wright MD, Helene Hedian MD, Che Harris MD

It is known that transgender people experience health inequalities. Disparities in hospital outcomes impacting transgender individuals have been inadequately explored. We conducted this retrospective cohort study using the National Inpatient Sample (01/2018–12/2019) to compare in-hospital mortality and utilization variables between cisgender and transgender individuals using regression analyses. Approximately two-thirds of hospitalizations for transgender patients (n = 10,245) were for psychiatric diagnoses. Compared to cisgender patients, there were no significant differences in adjusted means differences (aMD) in length of stay (LOS) (aMD = −0.29; p = .16) or total charges (aMD = −$486; p = .56). An additional 4870 transgender patients were admitted for medical diagnoses. Transgender and cisgender individuals had similar adjusted odds ratios (aOR) for in-hospital mortality (aOR = 0.96; p = .88) and total hospital charges (aMD = −$3118; p = .21). However, transgender individuals had longer LOS (aMD = +0.46 days; confidence interval [CI]: 0.15–0.90; p = .04). When comparing mortality and resource utilization between cisgender and transgender individuals, differences were negligible.

众所周知,变性人的健康状况不平等。对影响变性人的住院结果差异的探讨还不够充分。我们利用全国住院病人样本(01/2018-12/2019)开展了这项回顾性队列研究,利用回归分析比较了顺性别者和跨性别者的院内死亡率和使用变量。变性患者(n = 10,245)中约有三分之二是因精神疾病住院。与同性患者相比,变性患者在住院时间(LOS)(aMD = -0.29;p = .16)或总费用(aMD = -486美元;p = .56)方面的调整均值差异(aMD)并无显著差异。另有 4870 名变性患者因医疗诊断入院。跨性别者和顺性别者的院内死亡率(aOR = 0.96;p = .88)和住院总费用(aMD = -3118美元;p = .21)的调整后几率比(aOR)相似。然而,变性人的住院时间更长(aMD = +0.46 天;置信区间 [CI]:0.15-0.90;p = .04)。在比较顺性别者和变性者的死亡率和资源利用率时,两者之间的差异可以忽略不计。
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引用次数: 0
Abstract 摘要
IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2024-04-13 DOI: 10.1002/jhm.13328
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引用次数: 0
期刊
Journal of hospital medicine
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