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Comparative analysis of transmissibility and case fatality ratio of SARS, MERS and COVID-19 via a mathematical modeling approach 基于数学模型的SARS、MERS和COVID-19的传播率和病死率对比分析
Pub Date : 2021-07-28 DOI: 10.4314/JFAS.V13I3.7
A. A. Ayoade, T. Latunde, R. Folaranmi
Coronavirus epidemics emerged in the 1960s and the world has witnessed seven coronavirus outbreaks since then. Four of the coronaviruses instigate human influenza while the rest: Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV), the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) trigger severe respiratory disorders (SARS, MERS and COVID-19 respectively). The etiology of SARS, MERS and COVID-19 are similar but their epidemiology, in terms of incubation period, infectivity, case fatality ratio and the serial interval differ. In an attempt to compare the infectivity and case fatality ratio of the diseases, a mathematical model was considered for each disease. The key epidemiological quantity, the basic reproduction number, was derived for each model to examine the transmission potential of each disease. The mortality rates for the diseases were also investigated by considering the global report of COVID-19 as of October 1 2020 together with the history of SARS and MERS. Results from the computations showed that COVID-19 had the highest transmission potential and at the same time the lowest case fatality ratio. It was also revealed that COVID-19 would have wrecked more havocs had its case fatality ratio was as high as that of MERS.
冠状病毒疫情出现于20世纪60年代,此后全球共发生了七次冠状病毒疫情。其中四种冠状病毒引发人类流感,其余的冠状病毒:严重急性呼吸综合征冠状病毒(SARS- cov)、中东呼吸综合征冠状病毒(MERS- cov)和严重急性呼吸综合征冠状病毒-2 (SARS- cov -2)引发严重呼吸系统疾病(分别为SARS、MERS和COVID-19)。SARS、MERS和COVID-19的病原学相似,但其流行病学在潜伏期、传染性、病死率和发病间隔等方面存在差异。为了比较这些疾病的传染性和病死率,我们考虑了每种疾病的数学模型。为每个模型导出关键流行病学数量,即基本繁殖数,以检验每种疾病的传播潜力。考虑到截至2020年10月1日的全球COVID-19报告,并结合SARS和MERS的历史,对疾病的死亡率进行了调查。计算结果表明,2019冠状病毒病的传播潜力最大,同时病死率最低。如果新冠肺炎的病死率与MERS一样高,将会造成更大的破坏。
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引用次数: 0
Facing floods in Tébessa City, Eastern Algeria, a morphometric and cartographic approach to prioritize intervention in the City's sub-watersheds using GIS and remote sensing 面对阿尔及利亚东部tsambessa市的洪水,采用形态计量学和制图学方法,利用地理信息系统和遥感优先干预该市的分流域
Pub Date : 2021-07-27 DOI: 10.4314/JFAS.V13I3.6
A. Hadjela, R. Annab, K. Seghir
The objective of this work is to determine the importance of the five partial sub-watersheds that penetrate the city of Tébessa and their water networks in the “Oued El Kabir” watershed , belonging to the semi-arid climate Characterized by torrential rains constituting a natural danger, in terms of the real dimensions of the floods, especially since the hydromorphological characteristics of the valleys are not clear on the ground, because of the urban expansion which carried them away. The study was based on the morphometric and cartographic approach which allows the comparison of sub-watersheds between them, through 12 indicators, to determine the most influential sub- watersheds using GIS and remote sensing The results showed that the “ennagues” sub-watershed is the most dangerous for the city, it is a priority for its protection, and the need to manage the most vulnerable parts.
这项工作的目的是从洪水的实际规模、,尤其是由于城市扩张将山谷带走,山谷的水文地貌特征在地面上并不清楚。这项研究基于形态计量和制图方法,该方法允许通过12个指标对它们之间的子流域进行比较,以使用GIS和遥感来确定最具影响力的子流域。结果表明,“围困”子流域对城市来说是最危险的,它是城市保护的优先事项,以及需要管理最脆弱的部分。
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引用次数: 0
Effect of Ramial Fragmented Wood amendments on the germination rate (%) of durum wheat 苎麻碎木改良剂对硬粒小麦发芽率(%)的影响
Pub Date : 2021-07-24 DOI: 10.4314/JFAS.V13I3.3
I. Kerrouche, K. Bazri, A.E.S. Zeltni, G. Ouahrani
The presence of organic matter in agricultural soils is an important factor in assessing the conditions of the soils. BRF and Manure are energy inputs that can improve the soil. The objective of our work is to study the influence of the contribution of Rameal Fragmented Wood (RFW) and cattle manure in the presence and absence of earthworms Octodrilus complanatus on the germination rate (%) of durum wheat (Tritucum durum) of the Hedba 3 variety. The study station is located in a semi-arid zone (Constantine, Algeria). the results obtained show that the contribution of RFW or RFW mixture and cattle manure in the presence and absence of earthworms Octodrilus complanatus has a beneficial effect on the the germination rate increased by 193.35% on average in the amended plots compared to the control plots.
农业土壤中有机质的存在是评估土壤条件的一个重要因素。BRF和肥料是可以改善土壤的能源投入。本研究的目的是研究在有无扁叶八角蚯蚓的条件下,Rameal Fragmented Wood(RFW)和牛粪对Hedba 3号硬粒小麦(Tritucum durum)发芽率(%)的影响。研究站位于半干旱地区(阿尔及利亚康斯坦丁)。结果表明,在有无扁叶八角蚯蚓的条件下,RFW或RFW混合物和牛粪对改良小区的发芽率有明显的影响,与对照小区相比,改良小区的平均发芽率提高了193.35%。
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引用次数: 0
Solvent effect on Hyper-Rayleigh scattering (HRS) first hyperpolarizability of substituted polyene: Part (I) 溶剂对取代多烯超瑞利散射(HRS)第一超极化率的影响(一)
Pub Date : 2021-07-24 DOI: 10.4314/JFAS.V13I3.2
N. S. Labidi
The first hyperpolarizabilities βHRS of substituted hexatriene molecules have been carried out to assess the effects of the bridge length, of the frequency dispersion as well as the solvent polarity. These calculations confirm the particular behaviour of the first hyperpolarizability βHRS, depolarization ratio and the anisotropy factor as a function of the incident light frequency and solvent polarity. The impact of the solvent and expanding the π-conjugated limit to improve the βHRS .Finally, the interplay between βHRS and β//, βvec, dN...N, Egap and the Kirkwood–Onsager factor [(ε–1)/(2ε + 1)] was established.
本文首次对取代六烯分子的超极化率βHRS进行了研究,以评估桥长度、频率色散以及溶剂极性对取代六烯分子超极化率的影响。这些计算证实了第一超极化率βHRS、退极化比和各向异性因子作为入射光频率和溶剂极性的函数的特殊行为。研究了溶剂和扩大π共轭极限对β hrs的影响。最后,研究了β hrs与β//、βvec、dN…建立了N、Egap和Kirkwood-Onsager因子[(ε-1)/(2ε + 1)]。
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引用次数: 2
Seawater problem in the alluvial coastal aquifer of Nador, Tipaza, Algeria 阿尔及利亚提帕萨纳多尔海岸冲积含水层的海水问题
Pub Date : 2021-07-24 DOI: 10.4314/JFAS.V13I3.5
A. Bouderbala, B. Remini, H. Saaed, A. Younsi
This work focuses to the study of the coastal aquifer of Tipaza in the north of Algeria, for highlights mechanisms of potential seawater intrusion into groundwater. Tipaza aquifer has been overexploited for irrigation and water supply, which caused a negatively impacts on its water quality. To investigate these impacts, many tools have been carried out as: monitoring of piezometric level and physico-chemical analysis of 24 wells from 2008 to 2012 and pumping tests. The piezometric map shows the existence of zero meter level inside the plain; which making this area vulnerable to seawater intrusion, where isovalue curves of some chemical parameters are in increasing towards the sea. Results show also a high concentration gradient of some parameters in the first two kilometers, at 1 mS.cm-1.km-1 for EC and 600 to 900 mg.L-1.km-1 for sodium and chlorides respectively. The hydrochemical study confirmed the hypothesis of seawater intrusion in the coastal aquifer of Nador.
这项工作的重点是对阿尔及利亚北部蒂帕萨沿海含水层的研究,以突出潜在的海水侵入地下水的机制。Tipaza含水层因灌溉和供水而被过度开采,对其水质造成了负面影响。为了研究这些影响,在2008年至2012年期间对24口井进行了压力水平监测和物理化学分析,并进行了泵送测试。测压图显示平原内部存在零米水平;这使得该地区容易受到海水入侵,其中一些化学参数的等值曲线向海增加。结果还表明,在前2公里,某些参数的浓度梯度很高,为1 mS.cm-1。EC和600到900毫克/升。钠和氯化物分别为Km-1。水化学研究证实了纳多尔沿海含水层存在海水入侵的假设。
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引用次数: 0
The geography of Covid-19 in Algeria: In search of demographical parameters of vulnerability 阿尔及利亚Covid-19的地理分布:寻找脆弱性的人口参数
Pub Date : 2021-06-10 DOI: 10.4314/JFAS.V13I3.1
M. Benarioua, S. Chettah
The pandemic spread of Covid-19 is worth examining by the geographic eye in order to highlight the spatial dimension of this propagation. The geographical approach is mainly convened to observe some of the territorializing aspects of coronavirus, through which it becomes possible to define the territorial specificities that intervene as vectors of vulnerability to the pandemic. Claiming to be one of the first geographical researches on Covid-19 in Algeria, this article proposes to question the correlated relationship between its propagation dynamics and the spatial and demographic characteristics of pandemic territories. The objective is to understand the behaviors of vulnerability or resistance of these territories, via geographical parameters. Such an understanding is principally useful in health prevention and action strategies.
新冠肺炎的大流行性传播值得用地理眼光来审视,以突出这种传播的空间维度。地理方法主要是为了观察冠状病毒的一些属地化方面,通过这些方面,可以将干预的领土特异性定义为易受疫情影响的媒介。本文声称是阿尔及利亚最早对新冠肺炎进行的地理研究之一,并提出质疑其传播动态与大流行地区的空间和人口特征之间的相关关系。目的是通过地理参数了解这些领土的脆弱性或抵抗行为。这种理解主要有助于健康预防和行动战略。
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引用次数: 0
ETHNOBOTANIC STUDY OF THE ATRIPLEX HALIMUS L. IN THE REGION OF SIDI BEL ABBES- WEST ALGERIAN 西阿尔及利亚锡迪-贝尔-阿贝斯地区岩藻的民族植物学研究
Pub Date : 2021-04-30 DOI: 10.4314/JFAS.V13I2.28
T. Hellal, H. Benchohra, L. Mederres
The Atriplex halimus L, whose vernacular name in Algeria « Guettaf », is a widespread palnt in the Sidi Bel Abbes region in western of Algeria. It is a plant species of the Chenopodiaceae family, much in demand by the population of the wilaya of Sidi Bel Abbes for the treatment of the genitourinary system, the digestive tract and its annexes, the cardiovascular and respiratory system. It is even indicated as hypoglycemic in diabetics.The objective of our study is an ethnobotanical investigation of the plant in question, where we will try to identify its common uses by the population of the region of Sidi Bel Abbes for healing purposes.Keywords: Atriplex halimus L, Chenopodiaceae, Treatment, Diseases, Ethnobotanical investigation.
Atriplex halimus L,其在阿尔及利亚的方言名称为“Guettaf”,是阿尔及利亚西部西迪贝尔阿贝斯地区的一种广泛分布的植物。它是Chenopodiaceae家族的一种植物,Sidi Bel Abbes的wilaya人口非常需要用于治疗泌尿生殖系统,消化道及其附件,心血管和呼吸系统。它甚至被认为是糖尿病患者的低血糖药。我们研究的目的是对所讨论的植物进行民族植物学调查,在那里我们将试图确定其在西迪贝尔阿贝斯地区人口中用于治疗目的的常见用途。关键词:盐柳,藜科,治疗,疾病,民族植物学调查
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引用次数: 0
WATER QUALITY CONTROL OF THREE SITES AT KEDARRA BARRAGE KEDARRA拦河坝三个站点的水质控制
Pub Date : 2021-04-30 DOI: 10.4314/JFAS.V13I2.18
N. Ghemmit-Doulache, N. Ouslimani
Study aim is to monitor water quality at three sites at Keddara barrage witch located on territory of Boumerdes-Algeria. Physico-chemical, bacteriological and heavy metal analyses were carried out on waters feeding barrage site A, within barrage site B and those leaving barrage corresponding to pumping waters site C. Physical qualities of all three waters largely meet WHO standards. Chemical qualities Results showed that hardness is greater at site C. A mineralization with low nitrate, chloride, phosphate and ammonium contents. DCO/DBO5 ratio < 3 (for all three sites), indicating that source of water pollution is of organic origin. Analysis results of all three samples by SAA revealed traces of heavy metals which confirm good water quality. Keddara barrage waters are charged with total coliform bacteria, enterococcus and Escherichia-coli, so these waters require bacteriological treatment.
研究目的是监测位于阿尔及利亚Boumerdes地区的Keddara拦河坝的三个地点的水质。对补给拦河坝A、拦河坝B内拦河坝的水域以及离开拦河坝对应抽水地点C的水域进行了理化、细菌和重金属分析。所有三种水域的物理质量基本符合世界卫生组织标准。化学性质结果表明,C位点硬度较高。A矿化具有较低的硝酸盐、氯化物、磷酸盐和铵含量。DCO/DBO5比值<3(三个点),表明水污染源为有机污染。SAA对所有三个样本的分析结果都显示出微量重金属,这证实了水质良好。Keddara拦河坝水域含有大肠杆菌、肠球菌和大肠杆菌,因此这些水域需要进行细菌处理。
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引用次数: 0
COMPUTATIONAL SCREENING AND QSAR STUDY ON A SERIES THEOPHYLLINE DERIVATIVES AS ALDH1A1 INHIBITORS 一系列茶碱衍生物aldh1a1抑制剂的计算筛选与qsar研究
Pub Date : 2021-04-28 DOI: 10.4314/JFAS.V13I2.17
Firas Fadel, N. Tchouar, S. Belaidi, F. Soualmia, O. Oukil, K. Ouadah
In the present study, we explored a series of molecules with anticancer activity, so that qualitative and quantitative studies of the structure-activity relationship (SAR/QSAR) were performed on seventeen theophylline derivatives. These are inhibitors of ALDH1A1. The present study shows the importance of quantum chemical descriptors, constitutional descriptors and hydrophobicity to develop a better QSAR model, whose studied descriptors are LogP, MW, Pol, MR, S, V, HE, DM, EHOMO and ELUMO. A multiple linear regression (MLR) and artificial neural networks (ANN) procedure was used to design the relationships between molecular descriptors and the inhibition of ALDH1A1 by theophylline derivatives. The validation and good quality of the QSAR model are confirmed by a strong correlation between experimental and predicted activity.
在本研究中,我们探索了一系列具有抗癌活性的分子,从而对17种茶碱衍生物的构效关系(SAR/QSAR)进行了定性和定量研究。这些是ALDH1A1的抑制剂。本研究表明了量子化学描述符、组成描述符和疏水性对于开发更好的QSAR模型的重要性,其研究的描述符为LogP、MW、Pol、MR、S、V、HE、DM、EHOMO和ELUMO。采用多元线性回归(MLR)和人工神经网络(ANN)程序设计了分子描述符与茶碱衍生物抑制ALDH1A1之间的关系。实验活性和预测活性之间的强相关性证实了QSAR模型的有效性和良好的质量。
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引用次数: 1
APPLICATION OF STATISTICAL METHODS TO THE STUDY OF THE SPATIO-TEMPORAL EVOLUTION OF THE PHYSICO-CHEMICAL PARAMETERS OF THE SURFACE WATERS OF THE CHERF WADI BASIN. ALGERIA 应用统计方法研究cherf wadi盆地地表水理化参数的时空演变阿尔及利亚
Pub Date : 2021-04-27 DOI: 10.4314/JFAS.V13I2.27
M. A. Bellazi, N. Zenati, N. Belahcene, Y. Berredjem, A. Gheid
The physico-chemical parameters of the surface waters of the Cherf wadi watershed experience considerable variations over space and time under the influence of natural or anthropogenic phenomena. The application of the Kruskal-Wallis test for the comparison of the physico-chemical parameters showed that there were very significant intersite differences for pH, electrical conductivity, bicarbonate, chloride and sodium; as well as significant differences between the dates for all the studied variables. The typology highlighted by principal component analysis and Hierarchical Classification Analysis is linked to the availability of mineral elements by the anthropic activities of variable intensity depending on the sites, is added a natural process of mineralization related to the contact water- rock and throughfall phenomena. Statistical processing also revealed two types of water. The first type represents waters with very strong mineralization with very high sodium and chloride values ​​characterizing the waters of site 5. The second type is marked by strong mineralization with high contents of Calcium. It characterizes the sites receiving discharges coming respectively from certain agglomerations not connected to the wastewater system and from the treatment plant.
在自然或人为现象的影响下,Cherf wadi流域地表水的物理化学参数在空间和时间上经历了相当大的变化。应用Kruskal-Wallis检验比较理化参数表明,pH、电导率、碳酸氢盐、氯化物和钠在不同种间存在极显著差异;以及所有研究变量的日期之间的显著差异。主成分分析和分层分类分析强调的类型与矿物元素的可获得性有关,这是由不同地点的不同强度的人为活动引起的,并添加了与接触水岩和穿透现象相关的自然矿化过程。统计处理还揭示了两种类型的水。第一类是矿化非常强的水,具有很高的钠和氯化物值,是5点水的特征。第二类矿化程度高,钙含量高。它描述了接收排放的地点,分别来自未连接到废水系统和处理厂的某些聚集物。
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引用次数: 0
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Journal of Fundamental and Applied Sciences
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