Journal of Health, Population, and Nutrition最新文献

Background: Metabolic syndrome (MetS) contributes to an increased risk of cardiovascular diseases. Traditional metrics like body mass index (BMI) have limitations in discerning fat distribution. The purpose of this study was to evaluate the diagnostic accuracy of traditional and novel anthropometric indices in metabolic syndrome and its components in the south coast of Iran.

Methods: In this cross-sectional study, 2694 adults aged 35 to 70 were included. Comprehensive anthropometric and biochemical data were collected and analyzed. There were eight anthropometric indices evaluated in this study, including a body shape index (ABSI), body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), body roundness index (BRI), abdominal volume index (AVI), weight-adjusted waist index (WWI) and waist-height ratio (WHtR).

Results: WHtR (AUC: 0.766 for males, 0.799 for females), BRI (AUC: 0.766 for males, 0.799 for females), and AVI (AUC: 0.769 for males, 0.793 for females) were the best predictors of MetS. ABSI had the weakest correlation with metabolic variables.

Conclusions: AVI, WHtR, BRI, and WHR were superior to other measures as anthropometric indexes for determining MetS and its components. The study contributes valuable insights into the utility of traditional and novel metrics in clinical practice, highlighting the need for standardized diagnostic approaches and further research in diverse populations.

Background: Kenya has ratified and enacted several frameworks and laws in a bid to reduce the incidence of IPV and improve disclosure of violence experience. With these legal and structural mechanisms in place, women's disclosure of IPV is expected to show a positive trend over the years. We examined the trends and factors associated with disclosure of IPV among women in Kenya.

Methods: The 2008, 2014 and 2022 Kenya demographic and health survey data was used, with a weighted sample of 6,093 women aged 15-49 years. The sample size for 2008, 2014 and 2022 were 1350, 1165, and 3578, respectively. Violence disclosure was the outcome variable. A logistic regression model was fitted to estimate the predicted probabilities (margins) of reporting violence for each year. Additionally, a multivariable logistic regression was performed to assess factors associated with violence disclosure using a backward stepwise approach.

Results: We found a statistically significant increase in the odds of disclosing violence by 65% from 2008 to 2022 [OR = 1.65; 95%CI: 1.41-1.94, p < 0.001]. The odds of disclosing violence increased significantly by 35% from 2008 to 2014 (OR = 1.35, p = 0.003), and further declined by 23% from 2014 to 2022 (OR = 1.23, p = 0.012). Violence disclosure significantly increased with age. Women in the richest wealth index (AOR = 1.78, 95% CI: 1.46-2.16), those currently working (AOR = 1.23, 95% CI: 1.08-1.41), had witnessed parental violence (AOR = 1.14, 95% CI: 1.01-1.29), or had partners who drank alcohol (AOR = 1.41, 95% CI: 1.24-1.59) were also more likely to disclose violence.

Conclusion: The findings from this study indicate that violence disclosure among women in Kenya has significantly increased over the years. Women in higher wealth quintile, currently employed, and those exposed to violence in their parental homes were more likely to disclose violence, highlighting the importance of economic empowerment and addressing intergenerational transmission of violence in increasing disclosure rates.

Background: Health is a key driver of the United Nations Sustainable Development Goals. This study examined the relationships between economic indicators, demographic metrics, and health system factors and morbidity due to non-communicable diseases, such as diseases of the circulatory system, in Kazakhstan.

Methods: This retrospective ecological study utilized regionally aggregated data from 2010 to 2020 for all 14 regions in Kazakhstan. Data on incidence rates of diseases of the circulatory system (DCS) and socioeconomic, demographic, and healthcare variables were sourced from the Bureau of National Statistics and the Ministry of Health. Variables included gross regional product per capita, population density, living wage, unemployment rates, average monthly salary, Gini coefficient, income below subsistence level, housing space per capita, average monthly wage in healthcare, doctor and nurse densities per 10,000 population, and number of hospital beds. A correlation analysis was performed followed by stepwise regression to identify significant predictors.

Results: The analysis identified that higher living wages (β = 0.7), population density (β = 0.275), nurse density (β = 0.212), and average monthly salary (β = 0.502) were positively associated with higher DCS incidence rates. Conversely, gross regional product per capita (β = -0.68), housing space per capita (β = -0.441), and income below the subsistence level (β = -0.161) were negatively associated with DCS incidence. The model explained approximately 63.7% of variance in DCS incidence.

Conclusions: Socioeconomic and healthcare factors significantly influence the incidence of circulatory diseases in Kazakhstan. Policies aimed at improving economic conditions such as increasing living wages and reducing unemployment may help lower DCS morbidity. Additionally, equitable distribution of healthcare resources like nurses could enhance early detection and management of circulatory diseases, contributing to better public health outcomes in a middle-income country setting.

Background: The emergence of a new pandemic SARS-CoV-2 (COVID-19) resulted in a high mortality rate across the world. This study sought to comprehensively analyze the Case Fatality Rate (CFR) associated with COVID-19 in the Khuzestan province of Iran". The primary objective was to discern patterns and determinants influencing CFR, shedding light on the evolving impact of the pandemic on morbidity and mortality.

Methods: A retrospective examination was performed on a dataset encompassing confirmed COVID-19 cases and related fatalities in Khuzestan. Data, spanning from December 2020 to April 2022, underwent rigorous statistical analysis. Demographic variables, comorbidities, and temporal trends were scrutinized to identify key factors influencing CFR.

Results: Preliminary findings revealed dynamic shifts in CFR, capturing the nuanced nature of the pandemic over time. Demographic nuances, particularly age and gender, emerged as significant determinants impacting CFR, the reported CFR of COVID-19 in Khuzestan province was 1.79%.

Conclusion: This study contributes critical insights into the CFR landscape of COVID-19 in Khuzestan, providing a foundation for evidence-based decision-making in public health. The identified factors influencing mortality rates offer valuable information for tailoring interventions and optimizing resource allocation. Continuous monitoring and further investigations are recommended to adapt strategies to the evolving nature of the pandemic.

Background: The manufacturing sector in Malaysia has been severely impacted by the COVID-19 pandemic. This is further exacerbated by Long COVID-19 symptoms among the manufacturing workers, which are proven to influence work performance and quality of life. Of note, there is currently a lack of knowledge regarding the burden of Long COVID-19 in the Malaysian manufacturing sector. As such, our study aims to investigate the prevalence and risk factors of Long COVID-19 symptoms among the manufacturing workers, and subsequently assess the prevalence and risk factors of adverse work outcomes among the workers with Long Covid-19 symptoms.

Methods: This is an exploratory mixed-methods study. In phase 1 (qualitative phase), three groups of participants (i.e., clinicians, employers, and workers) will be invited to participate to focus group discussions (FGDs) until thematic saturation. The aim of the FGDs is to explore the understanding, experience, and potential risk factors of Long Covid-19 among manufacturing workers. Findings from the FGDs will be analysed thematically. Themes generated from the FGDs will be used to generate items in a new questionnaire. The newly developed questionnaire will be validated using a fuzzy Delphi study, which will also be conducted among clinicians, employers, and workers. Phase 2 is a cross-sectional study that will be conducted among manufacturing workers across all states in Malaysia to identify the prevalence and risk factors of Long COVID-19, as well as the prevalence and risk factors of adverse work outcomes among workers with Long COVID-19. A multistage cluster sampling will be used to collect data from 4500 manufacturing workers in Malaysia. Logistic regression will be performed to determine the association between risk factors with both Long COVID-19 and adverse work outcomes.

Conclusion: Once the prevalence and risk factors of Long COVID and its associated adverse work outcome are identified, timely support and effective interventions could be provided to manufacturing workers to maintain their health and productivity.

Ethical considerations: Ethical approval has been granted by the Research Ethics Committee of the National University of Malaysia (JEP-2023-607) and the Medical Research and Ethics Committee (MREC) Malaysia (NMRR ID-23-03310-H3E).

Background: Haff disease is a condition that has emerged in China in recent years, primarily associated with the consumption of crayfish. Despite its increasing incidence, the exact cause of Haff disease remains unknown, prompting further investigation into its potential triggers and risk factors. The purpose of this system review is to investigate and summarize the current understanding of Haff disease and provide insights into the etiology and pathogenesis of Haff disease by collecting and analyzing data from a large number of patients.

Method: Systematic searches were conducted in PubMed, CNKI, and Wanfang Databases to investigate and summarize Haff disease by crayfish consumption in China over recent years. The search included observational studies published up to May 1, 2024.

Result: This review collected data from 1437 patients and conducted a comprehensive analysis of symptoms. In-depth examinations of patient symptoms revealed that nearly all patients exhibited abnormally elevated serum creatine kinase levels and muscular pain, while some also experienced changes in urine color, abdominal discomfort, and chest pain. Risk factors associated with Haff disease from crayfish consumption included high crayfish consumption, alcohol use, the consumption of specific crayfish organs such as the head, liver, and pancreas, and the consumption of wild crayfish.

Conclusion: Haff disease is indeed related to the consumption of crayfish, which may be due to the presence of an unknown heat stable toxin in crayfish. During the research process, many risk factors were identified, and it is recommended that people who consume crayfish pay attention to these risk factors and take appropriate preventive measures to minimize the risk of illness.

Background: Poor maternal nutrition is a significant public health problem, especially in conflict-affected areas. Lactating mothers are particularly vulnerable due to increased nutritional demands. The recent conflict in the Tigray region has resulted in serious crises and disruptions, worsening maternal undernutrition.

Objective: This study aimed to determine the post-war nutritional status of lactating mothers, in Tigray, Ethiopia, 2024.

Methods: A household-based cross-sectional study was conducted from January 16 to February 14, 2024, across six zones of Tigray, excluding the Western zone, which included 1245 lactating mothers with children under six months of age. Data were collected through a structured interview-based questionnaire designed in KoboToolBox. The collected data were managed and analyzed via Stata version 17 software. Descriptive statistics and bivariate and multivariable robust (modified) Poisson regression models were fitted to identify the factors associated with maternal undernutrition, after checking the necessary model assumptions. Adjusted prevalence rates with 95% confidence intervals were used as measures of effects and statistical significance.

Results: The prevalence of undernutrition among lactating mothers was 55.2% (95% CI: 52.3-58.1). The proportion of undernourished lactating mothers was greater in rural areas (60.7%: 57.3-64.0) than in urban (41.8%: 36.5-47.2). The factors independently associated with maternal undernutrition included elementary education [aPR (95% C.I): 1.1(1.01-1.3)], rural residence [aPR (95% C.I): 1.3(1.1-1.5)], iodized salt use [aPR (95% C.I): 0.9(0.8-0.99)], and low meal frequency [aPR (95% C.I): 1.3(1.2-1.5)].

Conclusions: This study revealed a high maternal undernutrition prevalence among lactating mothers in Tigray in the post-conflict era. Therefore, interventions targeting educational opportunities, iodized salt use, and adequate meal frequency may help improve the nutritional status of lactating mothers in the conflict-affected areas in Tigray, Ethiopia.

Background: Non-prescription use of Tramadol is increasingly becoming common among vulnerable populations. This study examines the factors associated with non-prescription use of Tramadol among youth in urban informal settlements in the Asokore Mampong Municipality, Ghana.

Methods: Cross-sectional data from Tramadol users aged 15 to 35 years living in urban informal settlements were analyzed. Non-prescription use of Tramadol was assessed using the item "Have you ever used Tramadol for any reason without a prescription from a healthcare professional?". The responses were dichotomized as yes = 1, otherwise = 0. Multivariable logistic regression models evaluated the factors associated with non-prescription use of Tramadol.

Results: Data on 200 Tramadol users were obtained. Family/friends (52.3%), were the main source of knowledge on Tramadol. Energy boost (43%) was the most cited reason for Tramadol use. Approximately 52% indicated a continuing non-prescription use of Tramadol for energy boost. Multivariable logistic regressions showed that those who lived alone (OR = 6.34: 95% CI = 2.03-19.82), migrants (OR = 3.97, 95% CI = 1.31-12.05) and the unemployed (OR = 3.57, 95% CI = 1.02-12.58) were significantly more likely to report non-prescription use of Tramadol.

Conclusions: Non-prescription use of Tramadol is a threat to the youth in urban informal settlements in the Asokore Mampong Municipality. Interventions such as strict drug monitoring and regulation, drug use education, strict parental supervision, and sustainable jobs may contribute to controlling non-prescription use of Tramadol.

Background: The Dietary Approach to Stop Hypertension (DASH) has shown positive effects on various health factors that may be related to pancreatic steatosis (PS). This study aimed to investigate the association between adherence to the DASH diet and the risk of developing PS.

Methods: This case-control study was conducted on 278 patients diagnosed with gallstone disease and referred to Taleghani Hospital (Tehran, Iran). Among the participants, 89 were diagnosed with PS based on an endoscopic ultrasound (EUS) examination, while 189 patients did not exhibit this condition. The dietary intake of patients was assessed using a validated food frequency questionnaire (FFQ). Participants were classified based on the DASH diet score. Multiple logistic regression models estimated crude and multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs).

Results: The mean ± SD of DASH score in PS patients and controls was 23.68 ± 4.38 and 25.27 ± 4.2, respectively (P = 0.006). The risk of PS in the highest tertile of DASH score was 64% lower than the lowest tertile (OR = 0.36, 95%CI: 0.17-0.75, P = 0.005) after full adjustment for confounders. Also, more intake of vegetables and whole grains and less intake of sodium, red and processed meat were each significantly associated with reduced risk of PS.

Conclusions: Our data prove that adherence to the DASH diet was associated with a lower risk of PS. Further prospective studies are warranted to confirm these associations and explore the underlying mechanisms.

Introduction: Statins are effective in reducing high cholesterol levels; however, due to associated side effects, many patients actively seek alternative medications. This review evaluates the efficacy, side effects, patient adherence, cost-effectiveness, and accessibility of dietary supplements (DS) as a treatment option for hypercholesterolemia.

Methods: This narrative review compares red yeast rice (RYR), flaxseed, artichokes, bergamot, Ayurvedic mixtures (with garlic as a prominent ingredient), and statins for treating hypercholesterolemia. We searched PubMed, Scopus, and Cochrane databases for studies published between 2012 and 2024 using "hypercholesterolemia" in combination with a dietary supplement (red yeast rice, flaxseed, artichokes, garlic, or bergamot). The selected articles were published until 28th January 2024 with no language restrictions.

Results: Study results suggest that alternative treatments using dietary supplements such as flaxseed, bergamot, or red yeast rice may effectively reduce cholesterol levels, with the specific value varying based on the study.

Conclusion: The following natural ingredients - red yeast rice, artichoke extract, bergamot, garlic, and flaxseed - have been specifically selected for their cholesterol-lowering properties. Based on consistent usage, except for aged garlic extract, these ingredients appear to have a beneficial impact on cholesterol levels. (1) It is advisable to conduct a comprehensive cohort study to assess the efficacy of relevant dietary supplements, particularly red yeast rice, bergamot, and flaxseed, in treating hypercholesterolemia. This is important due to the varying effectiveness of alternative treatments. However, there are lingering concerns regarding the lack of supervision and quality control that require attention. (2) Further research into the specific molecular composition and the underlying mechanisms by which it reduces cholesterol levels is warranted.