Pub Date : 2025-12-26DOI: 10.1186/s41043-025-01151-3
Moses Festo Towongo, Olusegun S Ewemooje, Morrison Okezie Ogu
Background: Despite global efforts to improve maternal health outcomes, many regions, including Uganda, continue to face challenges in achieving optimal maternal healthcare utilization. This study aims to investigate how restricted autonomy in household decision-making by significant others affects inadequate use of maternal healthcare services among married women in Uganda. Inadequate use of maternal healthcare services refers to not meeting all four WHO-recommended standards for ANC timing, ANC visits, place of delivery, and PNC timing.
Methods: Secondary data from the latest 2016 Uganda Demographic and Health Survey (UDHS 2016) were used for this study. Data from 7906 married women of childbearing age were analyzed using a multilevel binary logistic regression approach.
Results: The inadequate use of maternal healthcare services was estimated to be 39.1%. The odds of inadequate use were 17% higher among women with moderate restricted autonomy in household decision-making by significant others compared to women with low restrictions [Adjusted Odds Ratio (AOR) = 1.17, 95% Confidence Interval (CI) = 1.02-1.34]. Inadequate use of MHCS decreases with an increase in the household wealth index. Women from the richest household [(AOR) = 0.52, 95% CI = 0.39,0.70] were less likely to report Inadequate use of maternal healthcare services compared to the poorest. Employed women were less likely [AOR = 0.73, 95% CI = 0.62-0.84] to report inadequate use of maternal healthcare services. Women who reside in the northern region of Uganda were significantly less likely [AOR = 0.72, 95% CI = 0.52-0.99] to report inadequate use of maternal healthcare services compared to those who reside in the central region.
Conclusion: The study concluded that the restricted autonomy in household decision-making by significant others plays a crucial role in the use of maternal healthcare services among married women in Uganda. Factors such as maternal age, household wealth index, employment status, and region of residence were also associated with inadequate use of maternal healthcare services. Therefore, to achieve Sustainable Development Goal (SDG) 3.1, the government and policymakers should engage significant others in maternal health programs, promote regional equity, female labor force participation, education, and autonomy in health decision-making.
背景:尽管全球努力改善孕产妇保健结果,但包括乌干达在内的许多地区在实现最佳孕产妇保健利用方面继续面临挑战。本研究旨在调查重要他人在家庭决策中受限制的自主权如何影响乌干达已婚妇女对孕产妇保健服务的不充分利用。孕产妇保健服务使用不足是指未达到世卫组织建议的四项标准,即产前分娩时机、产前就诊、分娩地点和产前分娩时机。方法:本研究使用最新的2016年乌干达人口与健康调查(UDHS 2016)的二手数据。对7906名已婚育龄妇女的数据进行多水平二元logistic回归分析。结果:孕产妇保健服务利用不足的比例为39.1%。在家庭决策中受到重要他人适度限制的妇女中,与受到低限制的妇女相比,不充分使用的几率高出17%[调整优势比(AOR) = 1.17, 95%可信区间(CI) = 1.02-1.34]。随着家庭财富指数的增加,MHCS使用不足的情况减少。与最贫困家庭相比,来自最富裕家庭的妇女[(AOR) = 0.52, 95% CI = 0.39,0.70]报告不充分利用孕产妇保健服务的可能性更小。就业妇女报告孕产妇保健服务使用不足的可能性较小[AOR = 0.73, 95% CI = 0.62-0.84]。与居住在中部地区的妇女相比,居住在乌干达北部地区的妇女报告未充分利用孕产妇保健服务的可能性显著降低[AOR = 0.72, 95% CI = 0.52-0.99]。结论:该研究得出结论,重要他人在家庭决策中的自主权受到限制,在乌干达已婚妇女使用孕产妇保健服务方面发挥了至关重要的作用。产妇年龄、家庭财富指数、就业状况和居住地区等因素也与产妇保健服务利用不足有关。因此,为了实现可持续发展目标3.1,政府和决策者应该让重要他人参与孕产妇保健计划,促进区域公平、女性劳动力参与、教育和健康决策自主权。
{"title":"The role of significant others in the inadequate use of maternal healthcare among married women in Uganda: a secondary analysis of the 2016 demographic and health survey.","authors":"Moses Festo Towongo, Olusegun S Ewemooje, Morrison Okezie Ogu","doi":"10.1186/s41043-025-01151-3","DOIUrl":"10.1186/s41043-025-01151-3","url":null,"abstract":"<p><strong>Background: </strong>Despite global efforts to improve maternal health outcomes, many regions, including Uganda, continue to face challenges in achieving optimal maternal healthcare utilization. This study aims to investigate how restricted autonomy in household decision-making by significant others affects inadequate use of maternal healthcare services among married women in Uganda. Inadequate use of maternal healthcare services refers to not meeting all four WHO-recommended standards for ANC timing, ANC visits, place of delivery, and PNC timing.</p><p><strong>Methods: </strong>Secondary data from the latest 2016 Uganda Demographic and Health Survey (UDHS 2016) were used for this study. Data from 7906 married women of childbearing age were analyzed using a multilevel binary logistic regression approach.</p><p><strong>Results: </strong>The inadequate use of maternal healthcare services was estimated to be 39.1%. The odds of inadequate use were 17% higher among women with moderate restricted autonomy in household decision-making by significant others compared to women with low restrictions [Adjusted Odds Ratio (AOR) = 1.17, 95% Confidence Interval (CI) = 1.02-1.34]. Inadequate use of MHCS decreases with an increase in the household wealth index. Women from the richest household [(AOR) = 0.52, 95% CI = 0.39,0.70] were less likely to report Inadequate use of maternal healthcare services compared to the poorest. Employed women were less likely [AOR = 0.73, 95% CI = 0.62-0.84] to report inadequate use of maternal healthcare services. Women who reside in the northern region of Uganda were significantly less likely [AOR = 0.72, 95% CI = 0.52-0.99] to report inadequate use of maternal healthcare services compared to those who reside in the central region.</p><p><strong>Conclusion: </strong>The study concluded that the restricted autonomy in household decision-making by significant others plays a crucial role in the use of maternal healthcare services among married women in Uganda. Factors such as maternal age, household wealth index, employment status, and region of residence were also associated with inadequate use of maternal healthcare services. Therefore, to achieve Sustainable Development Goal (SDG) 3.1, the government and policymakers should engage significant others in maternal health programs, promote regional equity, female labor force participation, education, and autonomy in health decision-making.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"31"},"PeriodicalIF":2.8,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12853674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-26DOI: 10.1186/s41043-025-01192-8
Robinah Nakayima, Stephen Ssemujju, Newton Ekakoro
Background: Despite advancements in the use of maternity care services, certain nations in sub-Saharan Africa continue to record unacceptable rates of maternal and perinatal morbidity and mortality, particularly in the postnatal period. This study aimed to assess the level of postnatal care service utilisation and associated factors among multiparous women in Buyamba County, Rakai District, Uganda.
Method: A community-based cross-sectional study involving women who had two or more children was conducted in four sub-counties of Buyamba County. Study participants were recruited using a systematic sampling technique. A structured and pre-tested questionnaire was used to gather data. Descriptive, bivariate and modified poisson regressions were computed using STATA version 14. Statistical significance was considered at p < 0.05 and the strength of statistical association was assessed by prevalence ratios with 95% confidence intervals.
Result: Out of 321 women who participated in the study, (81.9%) were married, (30.8%) were aged 35-44 years, (71.0%) attended antenatal care (ANC) during their previous pregnancy, (94.7%) delivered normally, and (94.4%) utilised postnatal care (PNC) services of which (67.2%) received immunisation for the children, (26.2%) acquired family planning counseling and (70.3%) had four or more PNC visits. Attending antenatal care (aPR = 1.750; 95% CI: 1.029-2.981), being aware of PNC services (aPR = 1.380; 95% CI: 1.016-1.875), receiving PNC education (aPR = 1.421; 95% CI: 1.048-1.923), having a normal delivery (aPR = 1.538; 95% CI: 1.055-2.241), and residing within 5 km of a health facility (aPR = 1.282; 95% CI: 1.006-1.632) were significantly associated with a higher likelihood of utilising postnatal care services. In contrast, being younger in age (aPR = 0.511; 95% CI: 0.347-0.752) and having a husband without formal education (aPR = 0.622; 95% CI: 0.454-0.853) were significantly associated with a lower likelihood of postnatal care services utilisation.
Conclusion: The study identified several maternal, spousal, and accessibility factors influencing postnatal care utilisation. Enhancing maternal health education, improving facility access, involving partners, and strengthening antenatal counseling and community sensitisation can increase PNC utilisation and improve maternal and neonatal health outcomes.
{"title":"Postnatal care service utilisation and associated factors among multiparous women in Buyamba County, Rakai District Uganda: a community-based cross-sectional study.","authors":"Robinah Nakayima, Stephen Ssemujju, Newton Ekakoro","doi":"10.1186/s41043-025-01192-8","DOIUrl":"10.1186/s41043-025-01192-8","url":null,"abstract":"<p><strong>Background: </strong>Despite advancements in the use of maternity care services, certain nations in sub-Saharan Africa continue to record unacceptable rates of maternal and perinatal morbidity and mortality, particularly in the postnatal period. This study aimed to assess the level of postnatal care service utilisation and associated factors among multiparous women in Buyamba County, Rakai District, Uganda.</p><p><strong>Method: </strong>A community-based cross-sectional study involving women who had two or more children was conducted in four sub-counties of Buyamba County. Study participants were recruited using a systematic sampling technique. A structured and pre-tested questionnaire was used to gather data. Descriptive, bivariate and modified poisson regressions were computed using STATA version 14. Statistical significance was considered at p < 0.05 and the strength of statistical association was assessed by prevalence ratios with 95% confidence intervals.</p><p><strong>Result: </strong>Out of 321 women who participated in the study, (81.9%) were married, (30.8%) were aged 35-44 years, (71.0%) attended antenatal care (ANC) during their previous pregnancy, (94.7%) delivered normally, and (94.4%) utilised postnatal care (PNC) services of which (67.2%) received immunisation for the children, (26.2%) acquired family planning counseling and (70.3%) had four or more PNC visits. Attending antenatal care (aPR = 1.750; 95% CI: 1.029-2.981), being aware of PNC services (aPR = 1.380; 95% CI: 1.016-1.875), receiving PNC education (aPR = 1.421; 95% CI: 1.048-1.923), having a normal delivery (aPR = 1.538; 95% CI: 1.055-2.241), and residing within 5 km of a health facility (aPR = 1.282; 95% CI: 1.006-1.632) were significantly associated with a higher likelihood of utilising postnatal care services. In contrast, being younger in age (aPR = 0.511; 95% CI: 0.347-0.752) and having a husband without formal education (aPR = 0.622; 95% CI: 0.454-0.853) were significantly associated with a lower likelihood of postnatal care services utilisation.</p><p><strong>Conclusion: </strong>The study identified several maternal, spousal, and accessibility factors influencing postnatal care utilisation. Enhancing maternal health education, improving facility access, involving partners, and strengthening antenatal counseling and community sensitisation can increase PNC utilisation and improve maternal and neonatal health outcomes.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"426"},"PeriodicalIF":2.8,"publicationDate":"2025-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12742198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145843845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: A community-based cross-sectional study was conducted to explore the association between Ultra-Processed Foods (UPFs) intake and the risk of frailty among community-dwelling older adults.
Methods: The current study was conducted on 368 community-dwelling older adults (with a mean age of 67.11 ± 6.21 years, of whom 55.2% were women) at health centers of Maragheh city in Iran. Body composition was measured by a body composition analyzer and physical activity by the short-form physical activity questionnaire. The UPFs intake were determined using NOVA classification, based on a self-administered 147-item semi-quantitative FFQ. Blood samples were derived for the evaluation of blood parameters. Raw and adjusted logistic regression models were used to examine the relationship between UPFs intake tertiles and the risk of frailty.
Results: Outcomes showed that the overall prevalence of frailty was 96 (26.1%). Results from the multivariable adjusted logistic regression model indicated that higher UPFs intake was significantly associated with higher odds of frailty (OR = 2.15, 95% CI: 1.13-4.09, P = 0.019). Subgroup analysis also indicated that among men, higher UPF intake was significantly related to higher odds of frailty (OR = 3.55, 95% CI: 1.20-10.51, P = 0.022), but not for women (P > 0.05). Additionally, the results revealed that higher UPF intake was significantly associated with the risk of exhaustion (OR = 3.97, 95% CI: 1.89-8.34, P < 0.001), especially among men (OR = 9.89, 95% CI: 3.10-31.60, P < 0.001), unlike women (P > 0.05). However, there were no significant associations between UPFs intake and other components of frailty, including the risk of weight loss, slowness, dominant hand grip strength and low physical activity.
Conclusions: The results highlighted that higher UPFs intake was significantly associated with the risk of frailty and exhaustion among community-dwelling older adults, especially for men. Future large-scale prospective and interventional studies are warranted to validate these associations and elucidate underlying biological mechanisms.
目的:一项以社区为基础的横断面研究旨在探讨超加工食品(upf)摄入量与社区老年人身体虚弱风险之间的关系。方法:本研究对伊朗Maragheh市卫生中心的368名社区老年人(平均年龄67.11±6.21岁,其中55.2%为女性)进行了研究。用身体成分分析仪测量身体成分,用简短的身体活动问卷测量身体活动。upf的摄入量是基于自我管理的147项半定量FFQ,使用NOVA分类来确定的。提取血液样本用于评估血液参数。使用原始和调整的逻辑回归模型来检验upf摄入量与虚弱风险之间的关系。结果:结果显示衰弱的总患病率为96(26.1%)。多变量调整logistic回归模型的结果表明,较高的upf摄入量与较高的虚弱几率显著相关(OR = 2.15, 95% CI: 1.13-4.09, P = 0.019)。亚组分析还表明,在男性中,较高的UPF摄入量与较高的虚弱几率显著相关(OR = 3.55, 95% CI: 1.20-10.51, P = 0.022),但对女性没有影响(P < 0.05)。此外,结果显示,较高的UPF摄入量与疲惫的风险显著相关(OR = 3.97, 95% CI: 1.89-8.34, P 0.05)。然而,摄入upf与身体虚弱的其他因素之间没有显著的关联,包括体重减轻的风险、行动迟缓、主要的手握力和低体力活动。结论:研究结果强调,在社区居住的老年人中,特别是男性,较高的upf摄入量与虚弱和疲惫的风险显著相关。未来有必要进行大规模的前瞻性和干预性研究,以验证这些关联并阐明潜在的生物学机制。
{"title":"Association between ultra-processed foods intake and frailty risk in community-dwelling older adults.","authors":"Jamal Hallajzadeh, Parasto Yousefi Tanha, Arian Azadnia, Alexei Wong, Sajjad Moradi","doi":"10.1186/s41043-025-01209-2","DOIUrl":"10.1186/s41043-025-01209-2","url":null,"abstract":"<p><strong>Aim: </strong>A community-based cross-sectional study was conducted to explore the association between Ultra-Processed Foods (UPFs) intake and the risk of frailty among community-dwelling older adults.</p><p><strong>Methods: </strong>The current study was conducted on 368 community-dwelling older adults (with a mean age of 67.11 ± 6.21 years, of whom 55.2% were women) at health centers of Maragheh city in Iran. Body composition was measured by a body composition analyzer and physical activity by the short-form physical activity questionnaire. The UPFs intake were determined using NOVA classification, based on a self-administered 147-item semi-quantitative FFQ. Blood samples were derived for the evaluation of blood parameters. Raw and adjusted logistic regression models were used to examine the relationship between UPFs intake tertiles and the risk of frailty.</p><p><strong>Results: </strong>Outcomes showed that the overall prevalence of frailty was 96 (26.1%). Results from the multivariable adjusted logistic regression model indicated that higher UPFs intake was significantly associated with higher odds of frailty (OR = 2.15, 95% CI: 1.13-4.09, P = 0.019). Subgroup analysis also indicated that among men, higher UPF intake was significantly related to higher odds of frailty (OR = 3.55, 95% CI: 1.20-10.51, P = 0.022), but not for women (P > 0.05). Additionally, the results revealed that higher UPF intake was significantly associated with the risk of exhaustion (OR = 3.97, 95% CI: 1.89-8.34, P < 0.001), especially among men (OR = 9.89, 95% CI: 3.10-31.60, P < 0.001), unlike women (P > 0.05). However, there were no significant associations between UPFs intake and other components of frailty, including the risk of weight loss, slowness, dominant hand grip strength and low physical activity.</p><p><strong>Conclusions: </strong>The results highlighted that higher UPFs intake was significantly associated with the risk of frailty and exhaustion among community-dwelling older adults, especially for men. Future large-scale prospective and interventional studies are warranted to validate these associations and elucidate underlying biological mechanisms.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"30"},"PeriodicalIF":2.8,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12849376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Background: </strong>Although the policy of screening tuberculosis (TB) in individuals with diabetes mellitus (DM) was suggested, the coexistence of TB and DM is rapidly increasing in China, hindering the country's TB elimination efforts. The delay in TB consultation and diagnosis poses a challenge for DM-TB patients. However, the impact of DM on TB is not fully understood. Our study aimed to evaluate patient and diagnosis delays in pulmonary tuberculosis (PTB) patients in Ningxia, China, investigate the relationship between DM comorbidity and delays, and provide recommendations for improving the implementation of TB prevention and control strategies.</p><p><strong>Methods: </strong>We examined all PTB patients with DM registered in the Chinese TB Information Management System (TBIMS) in the Ningxia region from 2016 to 2019. Patient delay was defined as > 20 days from symptom onset to first medical consultation, and diagnosis delay as > 1 day from first consultation to diagnosis, both measured in days. In our study, possible covariates were screened based on relevant literatures, then mediating variables were excluded, and finally covariates were screened by univariate analysis. Propensity score matching (PSM) was conducted (1:1 nearest matching with a caliper of 0.25 standard deviation (SD) of the propensity score (PS), without replacement) using covariates including sex, age, ethnicity, household registration, occupation, type of hospital for initial PTB diagnosis, level of hospital for initial PTB diagnosis, X-ray, the presence of other types of TB, and patient source. Logistic regression was then employed to assess the impact of DM on patient and diagnosis delays. Additionally, we conducted sensitivity analyses, exploring different ratios and caliper sizes, and mahalanobis distance matching. To address the potential for residual confounding by age, we conducted a further sensitivity analysis using age as a continuous variable in the PS model.</p><p><strong>Results: </strong>Out of 9,625 PTB patients registered in TBIMS, 260 (2.7%) were also diagnosed with DM. In the unadjusted analysis, there was no difference in the median duration of patient delay between NDM-PTB and DM-PTB patients (20 days vs. 22 days, P > 0.05), while the median diagnosis delay was significantly longer in DM-PTB patients (1 day vs. 3 days, P < 0.05). However, after PSM to control for confounders, regression analysis indicated that DM was associated with a higher likelihood of experiencing patient delay [odds ratio (OR) = 1.85; 95% confidence interval (CI) = 1.30-2.64], but not with diagnosis delay (OR = 1.29; 95% CI = 0.89-1.87). In conclusion, after balancing baseline characteristics, DM was a risk factor for patient delay in PTB patients, but not for diagnosis delay.</p><p><strong>Conclusions: </strong>Our study revealed that DM only exacerbated patient delay and ultimately had no significant effect on diagnosis delay. This suggests that screening for TB in
{"title":"Under the bidirectional screening policy, impact of diabetes mellitus on patient and diagnosis delays of pulmonary tuberculosis patients in Ningxia, China: a propensity score analysis.","authors":"Ying Zhang, Juan Lei, Wenxuan Li, Ye Li, Libo Liang, Xiaomei Tian, Wei Liu, Zehui Li, Siqi Wu, Longjia Wu, Xiaolin Wei, Hui Yin","doi":"10.1186/s41043-025-01195-5","DOIUrl":"10.1186/s41043-025-01195-5","url":null,"abstract":"<p><strong>Background: </strong>Although the policy of screening tuberculosis (TB) in individuals with diabetes mellitus (DM) was suggested, the coexistence of TB and DM is rapidly increasing in China, hindering the country's TB elimination efforts. The delay in TB consultation and diagnosis poses a challenge for DM-TB patients. However, the impact of DM on TB is not fully understood. Our study aimed to evaluate patient and diagnosis delays in pulmonary tuberculosis (PTB) patients in Ningxia, China, investigate the relationship between DM comorbidity and delays, and provide recommendations for improving the implementation of TB prevention and control strategies.</p><p><strong>Methods: </strong>We examined all PTB patients with DM registered in the Chinese TB Information Management System (TBIMS) in the Ningxia region from 2016 to 2019. Patient delay was defined as > 20 days from symptom onset to first medical consultation, and diagnosis delay as > 1 day from first consultation to diagnosis, both measured in days. In our study, possible covariates were screened based on relevant literatures, then mediating variables were excluded, and finally covariates were screened by univariate analysis. Propensity score matching (PSM) was conducted (1:1 nearest matching with a caliper of 0.25 standard deviation (SD) of the propensity score (PS), without replacement) using covariates including sex, age, ethnicity, household registration, occupation, type of hospital for initial PTB diagnosis, level of hospital for initial PTB diagnosis, X-ray, the presence of other types of TB, and patient source. Logistic regression was then employed to assess the impact of DM on patient and diagnosis delays. Additionally, we conducted sensitivity analyses, exploring different ratios and caliper sizes, and mahalanobis distance matching. To address the potential for residual confounding by age, we conducted a further sensitivity analysis using age as a continuous variable in the PS model.</p><p><strong>Results: </strong>Out of 9,625 PTB patients registered in TBIMS, 260 (2.7%) were also diagnosed with DM. In the unadjusted analysis, there was no difference in the median duration of patient delay between NDM-PTB and DM-PTB patients (20 days vs. 22 days, P > 0.05), while the median diagnosis delay was significantly longer in DM-PTB patients (1 day vs. 3 days, P < 0.05). However, after PSM to control for confounders, regression analysis indicated that DM was associated with a higher likelihood of experiencing patient delay [odds ratio (OR) = 1.85; 95% confidence interval (CI) = 1.30-2.64], but not with diagnosis delay (OR = 1.29; 95% CI = 0.89-1.87). In conclusion, after balancing baseline characteristics, DM was a risk factor for patient delay in PTB patients, but not for diagnosis delay.</p><p><strong>Conclusions: </strong>Our study revealed that DM only exacerbated patient delay and ultimately had no significant effect on diagnosis delay. This suggests that screening for TB in ","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"28"},"PeriodicalIF":2.8,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145827912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Malnutrition is a significant public health concern affecting many populations, particularly in developing countries such as India and its neighboring economies. It can lead to adverse health outcomes, including stunted growth, impaired cognition, and increased susceptibility to disease. This review attempts to summarize the problems associated with malnutrition in different age groups in India and its neighboring countries, and the accompanying factors contributing to it. We also summarize the different biofortification techniques, which, when appropriately implemented, can alleviate these problems and potentially increase the availability and accessibility of crucial micronutrients such as vitamins and minerals in the diets of vulnerable populations. Government schemes and policies for scaling up biofortification interventions, as well as increasing public awareness and acceptance of biofortified crops, have also been delineated. In conclusion, while significant challenges remain, biofortification represents a promising approach for combating malnutrition, although further research and evaluations are needed to realize its potential impact fully.
{"title":"Biofortification as a sustainable strategy to address micronutrient malnutrition in South Asia.","authors":"Aneesha VijayaKumar, Irshaan Syed, Harshavardhan Dhulipalla, Payel Ghosh, Laxmikarthika V Srinivasan, Faraz Ahmad, Sandeep Singh Rana, Vipin Singh","doi":"10.1186/s41043-025-01108-6","DOIUrl":"10.1186/s41043-025-01108-6","url":null,"abstract":"<p><p>Malnutrition is a significant public health concern affecting many populations, particularly in developing countries such as India and its neighboring economies. It can lead to adverse health outcomes, including stunted growth, impaired cognition, and increased susceptibility to disease. This review attempts to summarize the problems associated with malnutrition in different age groups in India and its neighboring countries, and the accompanying factors contributing to it. We also summarize the different biofortification techniques, which, when appropriately implemented, can alleviate these problems and potentially increase the availability and accessibility of crucial micronutrients such as vitamins and minerals in the diets of vulnerable populations. Government schemes and policies for scaling up biofortification interventions, as well as increasing public awareness and acceptance of biofortified crops, have also been delineated. In conclusion, while significant challenges remain, biofortification represents a promising approach for combating malnutrition, although further research and evaluations are needed to realize its potential impact fully.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"425"},"PeriodicalIF":2.8,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12729806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145827898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-23DOI: 10.1186/s41043-025-01164-y
Vandana Garg, Joseph Lin, Aida Gadzhieva-Moore, Shi Mun Yee, Abhijeet Dhiman, Richa Kumari, Sheryl S L Tan
Background: Multivitamin and mineral (MVM) supplements have been shown to provide various health benefits, including enhanced energy, skin health, metabolism, and immune function. This study explored the impact of MVM supplements based on users' experience in Taiwan.
Methods: This retrospective, real-world, cross-sectional study included 400 respondents, aged 35-60 years, residing in Taiwan. Data were collected via an online survey. Respondents self-reported perceived benefits across six youthful vitality benefits: energy, metabolism, sleep, mental alertness, skin health and complexion, and spirit. Additional assessments covered perceived immunity, general health, quality-of-life (QoL), well-being, user attitude and perception. Subgroup analyses was performed post hoc based on gender (male vs. female), age (< 50 vs. ≥50 years) and frequency of use (daily vs. occasional) to explore potential subgroup differences in perceived benefits.
Results: A total of 93% of users agreed that MVM supplements support at least one out of six youthful vitality benefits. Users reported several perceived benefits: energy support (59.00%), improved metabolism (59.75%), improved complexion (53.25%), normal immune functioning (66.25%), confident in maintaining overall health (63.25%). Satisfaction levels were notably high, with 74.50% expressing satisfaction with product use, 72.50% trusting the product, and 79.00% showed willingness to repurchase. Subgroup analyses suggested that males, daily users, and users aged ≥ 50 years experienced more favorable outcomes across several parameters as compared to their respective counterparts.
Conclusion: This study provides real-world evidence that MVM supplements are widely perceived to support youthful vitality, immunity, general health, and QoL. These user-reported outcomes complement existing clinical research by highlighting benefits experienced in everyday settings, especially among daily users and those aged 50 and above. The high satisfaction and trust levels observed further reinforce the relevance of MVM supplements as a self-care strategy. By bridging the gap between controlled trials and consumer experience, this study adds valuable context to the science and recommendation of micronutrient supplementation.
{"title":"The role of multivitamin and mineral supplements in supporting health and well-being: a retrospective cross-sectional study in Taiwan.","authors":"Vandana Garg, Joseph Lin, Aida Gadzhieva-Moore, Shi Mun Yee, Abhijeet Dhiman, Richa Kumari, Sheryl S L Tan","doi":"10.1186/s41043-025-01164-y","DOIUrl":"10.1186/s41043-025-01164-y","url":null,"abstract":"<p><strong>Background: </strong>Multivitamin and mineral (MVM) supplements have been shown to provide various health benefits, including enhanced energy, skin health, metabolism, and immune function. This study explored the impact of MVM supplements based on users' experience in Taiwan.</p><p><strong>Methods: </strong>This retrospective, real-world, cross-sectional study included 400 respondents, aged 35-60 years, residing in Taiwan. Data were collected via an online survey. Respondents self-reported perceived benefits across six youthful vitality benefits: energy, metabolism, sleep, mental alertness, skin health and complexion, and spirit. Additional assessments covered perceived immunity, general health, quality-of-life (QoL), well-being, user attitude and perception. Subgroup analyses was performed post hoc based on gender (male vs. female), age (< 50 vs. ≥50 years) and frequency of use (daily vs. occasional) to explore potential subgroup differences in perceived benefits.</p><p><strong>Results: </strong>A total of 93% of users agreed that MVM supplements support at least one out of six youthful vitality benefits. Users reported several perceived benefits: energy support (59.00%), improved metabolism (59.75%), improved complexion (53.25%), normal immune functioning (66.25%), confident in maintaining overall health (63.25%). Satisfaction levels were notably high, with 74.50% expressing satisfaction with product use, 72.50% trusting the product, and 79.00% showed willingness to repurchase. Subgroup analyses suggested that males, daily users, and users aged ≥ 50 years experienced more favorable outcomes across several parameters as compared to their respective counterparts.</p><p><strong>Conclusion: </strong>This study provides real-world evidence that MVM supplements are widely perceived to support youthful vitality, immunity, general health, and QoL. These user-reported outcomes complement existing clinical research by highlighting benefits experienced in everyday settings, especially among daily users and those aged 50 and above. The high satisfaction and trust levels observed further reinforce the relevance of MVM supplements as a self-care strategy. By bridging the gap between controlled trials and consumer experience, this study adds valuable context to the science and recommendation of micronutrient supplementation.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"423"},"PeriodicalIF":2.8,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12729314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145819759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-23DOI: 10.1186/s41043-025-01190-w
Fatma Elif Eroğlu, Büşra Açıkalın Göktürk, Zeynep Begüm Kalyoncu Atasoy, Özge Mengi Çelik
Background: Sustainable food literacy, healthy life awareness, and adherence to sustainable dietary models such as the Mediterranean diet are critical for promoting both public health and environmental well-being. While sociodemographic influences have been examined in previous research, the potential role of social media addiction as a behavioral factor in shaping sustainable dietary practices remains underexplored.
Objectives: This study aimed to investigate how sustainable food literacy, healthy life awareness, and social media addiction relate to Mediterranean diet adherence and nutritional sustainability in adults, while also accounting for key sociodemographic characteristics.
Methods: This cross-sectional online study included 2,263 adults (60.5% female; mean age, 29.4 ± 11.7 years; mean BMI, 24.54 ± 6.8 kg/m²). Data were collected using the Sustainable Food Literacy Scale (SFLS), Social Media Addiction Scale (SMAS), Adherence to the Mediterranean Diet and Nutritional Sustainability Questionnaire Turkish Version (MedQ-Sus-Tr), and Healthy Life Awareness Scale (HLAS). Pearson correlation and multiple linear regression analyses were performed.
Results: Based on the MedQ-Sus-Tr, 91.0% of participants were classified as having low adherence to the Mediterranean diet, and 70.1% were classified as having low nutritional sustainability. Mediterranean diet adherence showed the strongest correlation with nutritional sustainability (r = 0.728, p < 0.001). Predictors of Mediterranean diet adherence included marital status, income, SFLS, and HLAS (R² = 0.365), while nutritional sustainability was predicted by marital status, income, SFLS, and HLAS (R² = 0.301). SFLS was associated with sex, education level, marital status, income, social media addiction, HLAS, Mediterranean diet adherence, and nutritional sustainability (R² = 0.704). HLAS was predicted by sex, age, SFLS, social media addiction, Mediterranean diet adherence, and nutritional sustainability (R² = 0.696).
Conclusions: Our findings highlight that higher sustainable food literacy and healthy life awareness significantly predict greater adherence to the Mediterranean diet and improved nutritional sustainability, regardless of sociodemographic characteristics. Social media addiction was positively associated with both literacy and awareness, though it did not directly predict dietary adherence or sustainability. These results suggest that while social media use may enhance exposure to nutrition-related information, its impact on actual dietary behaviors is less direct. Targeted interventions should therefore leverage the informational potential of digital platforms, while also fostering translation of awareness into healthier and more sustainable eating practices.
背景:可持续食品素养、健康生活意识和坚持地中海饮食等可持续饮食模式对于促进公众健康和环境福祉至关重要。虽然在之前的研究中已经研究了社会人口统计学的影响,但社交媒体成瘾作为一种行为因素在塑造可持续饮食习惯方面的潜在作用仍未得到充分探索。目的:本研究旨在调查可持续食品素养、健康生活意识和社交媒体成瘾与成人地中海饮食依从性和营养可持续性之间的关系,同时也考虑了关键的社会人口统计学特征。方法:该横断面在线研究包括2263名成年人(60.5%为女性,平均年龄29.4±11.7岁,平均BMI为24.54±6.8 kg/m²)。使用可持续食物素养量表(SFLS)、社交媒体成瘾量表(SMAS)、地中海饮食依从性和营养可持续性问卷土耳其版(medq - su - tr)和健康生活意识量表(HLAS)收集数据。进行Pearson相关和多元线性回归分析。结果:根据MedQ-Sus-Tr, 91.0%的参与者被归类为地中海饮食依从性低,70.1%被归类为营养可持续性低。结论:我们的研究结果强调,无论社会人口特征如何,更高的可持续食品素养和健康生活意识显著地预示着更强的地中海饮食依从性和更好的营养可持续性。社交媒体成瘾与识字和意识呈正相关,尽管它并不能直接预测饮食的坚持或可持续性。这些结果表明,虽然社交媒体的使用可能会增加对营养相关信息的接触,但它对实际饮食行为的影响并不直接。因此,有针对性的干预措施应利用数字平台的信息潜力,同时促进将意识转化为更健康和更可持续的饮食习惯。
{"title":"The relationship between sustainable dietary behaviors, sustainable food literacy, healthy life awareness, and social media addiction in adults: a cross-sectional study in Türkiye.","authors":"Fatma Elif Eroğlu, Büşra Açıkalın Göktürk, Zeynep Begüm Kalyoncu Atasoy, Özge Mengi Çelik","doi":"10.1186/s41043-025-01190-w","DOIUrl":"10.1186/s41043-025-01190-w","url":null,"abstract":"<p><strong>Background: </strong>Sustainable food literacy, healthy life awareness, and adherence to sustainable dietary models such as the Mediterranean diet are critical for promoting both public health and environmental well-being. While sociodemographic influences have been examined in previous research, the potential role of social media addiction as a behavioral factor in shaping sustainable dietary practices remains underexplored.</p><p><strong>Objectives: </strong>This study aimed to investigate how sustainable food literacy, healthy life awareness, and social media addiction relate to Mediterranean diet adherence and nutritional sustainability in adults, while also accounting for key sociodemographic characteristics.</p><p><strong>Methods: </strong>This cross-sectional online study included 2,263 adults (60.5% female; mean age, 29.4 ± 11.7 years; mean BMI, 24.54 ± 6.8 kg/m²). Data were collected using the Sustainable Food Literacy Scale (SFLS), Social Media Addiction Scale (SMAS), Adherence to the Mediterranean Diet and Nutritional Sustainability Questionnaire Turkish Version (MedQ-Sus-Tr), and Healthy Life Awareness Scale (HLAS). Pearson correlation and multiple linear regression analyses were performed.</p><p><strong>Results: </strong>Based on the MedQ-Sus-Tr, 91.0% of participants were classified as having low adherence to the Mediterranean diet, and 70.1% were classified as having low nutritional sustainability. Mediterranean diet adherence showed the strongest correlation with nutritional sustainability (r = 0.728, p < 0.001). Predictors of Mediterranean diet adherence included marital status, income, SFLS, and HLAS (R² = 0.365), while nutritional sustainability was predicted by marital status, income, SFLS, and HLAS (R² = 0.301). SFLS was associated with sex, education level, marital status, income, social media addiction, HLAS, Mediterranean diet adherence, and nutritional sustainability (R² = 0.704). HLAS was predicted by sex, age, SFLS, social media addiction, Mediterranean diet adherence, and nutritional sustainability (R² = 0.696).</p><p><strong>Conclusions: </strong>Our findings highlight that higher sustainable food literacy and healthy life awareness significantly predict greater adherence to the Mediterranean diet and improved nutritional sustainability, regardless of sociodemographic characteristics. Social media addiction was positively associated with both literacy and awareness, though it did not directly predict dietary adherence or sustainability. These results suggest that while social media use may enhance exposure to nutrition-related information, its impact on actual dietary behaviors is less direct. Targeted interventions should therefore leverage the informational potential of digital platforms, while also fostering translation of awareness into healthier and more sustainable eating practices.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"27"},"PeriodicalIF":2.8,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145819746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1186/s41043-025-01120-w
Yang Wang, Xiang Miao, Aiping Hu
Objective: This study aimed to investigate the effect of gestational diabetes mellitus (GDM) on maternal serum uric acid (SUA) levels.
Methods: We searched PubMed, Embase, Web of Science, Scopus and the Cochrane Library from inception to 31 January 2025. Cohort and case-control studies reporting SUA at or before 28 weeks' gestation and subsequent GDM were eligible. Random effects meta analyses with Hartung-Knapp adjustment synthesised.
Results: Sixteen studies (19 reports) encompassing 25 212 GDM cases and 148 519 normoglycaemic controls met all criteria. In eight studies with continuous data (2 690 GDM vs. 6 250 controls), women who developed GDM had an average first trimester SUA 44.3 µmol L⁻¹ higher than controls (95% CI 10.3-78.3; I²=96.9%). Ten studies providing categorical estimates yielded a pooled adjusted OR of 2.35 (95% CI 1.54-3.58; I² = 98.7%), indicating a > two fold risk of GDM with elevated SUA. However, substantial heterogeneity was observed across studies (I² >95%). Sequential omission of individual studies, alternative τ² estimators and restriction to high quality cohorts all preserved statistical significance. Funnel plot asymmetry suggested mild small study effects for categorical data but trim and fill adjustment changed the OR by < 10%.
Conclusions: Elevated SUA measured as early as the periconceptional period is consistently associated with an approximately two fold increase in GDM risk. Given its low cost and routine availability, first trimester SUA may hold promise as an adjunctive early pregnancy risk stratification tool, though further validation studies are needed to confirm its clinical utility.
目的:探讨妊娠期糖尿病(GDM)对孕妇血清尿酸(SUA)水平的影响。方法:检索PubMed、Embase、Web of Science、Scopus和Cochrane Library自成立至2025年1月31日的文献。报告妊娠28周或之前发生SUA和随后发生GDM的队列和病例对照研究符合条件。随机效应meta分析与Hartung-Knapp校正。结果:16项研究(19篇报道)包括25212例GDM病例和148519例正常血糖对照符合所有标准。在8项具有连续数据的研究中(2 690名GDM对6 250名对照组),患有GDM的妇女妊娠早期平均SUA (44.3 μ mol L -毒血症)比对照组高(95% CI 10.3-78.3; I²=96.9%)。10项提供分类估计的研究得出的合并调整OR为2.35 (95% CI 1.54-3.58; I²= 98.7%),表明SUA升高的GDM风险为bb0 - 2倍。然而,在研究中观察到大量的异质性(I²>95%)。个别研究的序贯遗漏、替代τ²估计值和对高质量队列的限制都保持了统计显著性。漏斗图不对称表明分类数据有轻微的小研究影响,但修剪和填充调整改变了OR结论:早在孕前期测量的高SUA始终与GDM风险增加约两倍相关。鉴于其低成本和常规可用性,妊娠早期SUA可能有望作为一种辅助早孕风险分层工具,尽管需要进一步的验证研究来证实其临床实用性。
{"title":"Effect of gestational diabetes mellitus on maternal serum uric acid levels: a systematic review and meta-analysis.","authors":"Yang Wang, Xiang Miao, Aiping Hu","doi":"10.1186/s41043-025-01120-w","DOIUrl":"10.1186/s41043-025-01120-w","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the effect of gestational diabetes mellitus (GDM) on maternal serum uric acid (SUA) levels.</p><p><strong>Methods: </strong>We searched PubMed, Embase, Web of Science, Scopus and the Cochrane Library from inception to 31 January 2025. Cohort and case-control studies reporting SUA at or before 28 weeks' gestation and subsequent GDM were eligible. Random effects meta analyses with Hartung-Knapp adjustment synthesised.</p><p><strong>Results: </strong>Sixteen studies (19 reports) encompassing 25 212 GDM cases and 148 519 normoglycaemic controls met all criteria. In eight studies with continuous data (2 690 GDM vs. 6 250 controls), women who developed GDM had an average first trimester SUA 44.3 µmol L⁻¹ higher than controls (95% CI 10.3-78.3; I²=96.9%). Ten studies providing categorical estimates yielded a pooled adjusted OR of 2.35 (95% CI 1.54-3.58; I² = 98.7%), indicating a > two fold risk of GDM with elevated SUA. However, substantial heterogeneity was observed across studies (I² >95%). Sequential omission of individual studies, alternative τ² estimators and restriction to high quality cohorts all preserved statistical significance. Funnel plot asymmetry suggested mild small study effects for categorical data but trim and fill adjustment changed the OR by < 10%.</p><p><strong>Conclusions: </strong>Elevated SUA measured as early as the periconceptional period is consistently associated with an approximately two fold increase in GDM risk. Given its low cost and routine availability, first trimester SUA may hold promise as an adjunctive early pregnancy risk stratification tool, though further validation studies are needed to confirm its clinical utility.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":"44 1","pages":"422"},"PeriodicalIF":2.8,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12717739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-19DOI: 10.1186/s41043-025-01178-6
Adolphe Ndikubwimana, William Checkley, Yunyun Chen, Thomas Clasen, Carmen Lucía Contreras, Anaite Diaz-Artiga, Gloriose Bankundiye, Ephrem Dusabimana, Lisa de Las Fuentes, Shirin Jabbarzadeh, Michael Johnson, Egide Kalisa, Patrick Karakwende, Miles A Kirby, Amy E Lovvorn, John P McCracken, Florien Ndagijimana, Theoneste Ntakirutimana, Jean de Dieu Ntivuguruzwa, Jennifer L Peel, Ajay Pillarisetti, Victor G Dávila-Román, Ghislaine Rosa, Sarada S Garg, Lisa M Thompson, Lance A Waller, Jiantong Wang, Maggie L Clark, Dana Boyd-Barr, Bonnie N Young
Background: Exposure to metals from the combustion of biomass via inhalation may result in negative health outcomes affecting a variety of organs and systems. Pregnant women cooking with biomass fuels may be exposed to metals, such as lead (Pb) and cadmium (Cd), and have unique risks for adverse health effects with potential impacts on the growing fetus. We assessed the associations between household air pollution and metals detected in dried blood spots from pregnant women at baseline in Rwanda.
Methods: We analyzed data from 781 pregnant women aged 18-35 years who resided in rural households using biomass fuel and who were enrolled in the Household Air Pollution Intervention Network (HAPIN) Trial in Rwanda. We explored associations between 24-h average natural log-transformed personal exposures to fine particulate matter (PM2.5), black carbon (BC), and carbon monoxide (CO) and K + standardized Pb and Cd concentrations using linear regression models adjusted for potential confounders (i.e., age, body mass index, bicycle ownership, fish consumption, and food insecurity).
Results: The adjusted models showed positive but non-significant associations between air pollutant concentrations and metals detected in blood: PM₂.₅ and Pb (β coefficient: 0.06; 95% CI - 0.03-0.15), BC and Pb (0.11; 95% CI - 0.01-0.24), PM₂.₅ and Cd (0.04; 95% CI - 0.02-0.09), and BC with Cd (0.02; 95% CI - 0.05-0.09).
Conclusions: While associations were not statistically significant, the directionally consistent increases in blood Pb and Cd with increased PM₂.₅ and BC exposures align with existing evidence and underscore the need for continued research and policy action to reduce household air pollution exposures and protect maternal and fetal health.
{"title":"Baseline exposure-response assessment of metals from dried blood spots and personal household air pollution concentrations among pregnant women in Rwanda: household air pollution intervention network trial.","authors":"Adolphe Ndikubwimana, William Checkley, Yunyun Chen, Thomas Clasen, Carmen Lucía Contreras, Anaite Diaz-Artiga, Gloriose Bankundiye, Ephrem Dusabimana, Lisa de Las Fuentes, Shirin Jabbarzadeh, Michael Johnson, Egide Kalisa, Patrick Karakwende, Miles A Kirby, Amy E Lovvorn, John P McCracken, Florien Ndagijimana, Theoneste Ntakirutimana, Jean de Dieu Ntivuguruzwa, Jennifer L Peel, Ajay Pillarisetti, Victor G Dávila-Román, Ghislaine Rosa, Sarada S Garg, Lisa M Thompson, Lance A Waller, Jiantong Wang, Maggie L Clark, Dana Boyd-Barr, Bonnie N Young","doi":"10.1186/s41043-025-01178-6","DOIUrl":"10.1186/s41043-025-01178-6","url":null,"abstract":"<p><strong>Background: </strong>Exposure to metals from the combustion of biomass via inhalation may result in negative health outcomes affecting a variety of organs and systems. Pregnant women cooking with biomass fuels may be exposed to metals, such as lead (Pb) and cadmium (Cd), and have unique risks for adverse health effects with potential impacts on the growing fetus. We assessed the associations between household air pollution and metals detected in dried blood spots from pregnant women at baseline in Rwanda.</p><p><strong>Methods: </strong>We analyzed data from 781 pregnant women aged 18-35 years who resided in rural households using biomass fuel and who were enrolled in the Household Air Pollution Intervention Network (HAPIN) Trial in Rwanda. We explored associations between 24-h average natural log-transformed personal exposures to fine particulate matter (PM<sub>2.5</sub>), black carbon (BC), and carbon monoxide (CO) and K + standardized Pb and Cd concentrations using linear regression models adjusted for potential confounders (i.e., age, body mass index, bicycle ownership, fish consumption, and food insecurity).</p><p><strong>Results: </strong>The adjusted models showed positive but non-significant associations between air pollutant concentrations and metals detected in blood: PM₂.₅ and Pb (β coefficient: 0.06; 95% CI - 0.03-0.15), BC and Pb (0.11; 95% CI - 0.01-0.24), PM₂.₅ and Cd (0.04; 95% CI - 0.02-0.09), and BC with Cd (0.02; 95% CI - 0.05-0.09).</p><p><strong>Conclusions: </strong>While associations were not statistically significant, the directionally consistent increases in blood Pb and Cd with increased PM₂.₅ and BC exposures align with existing evidence and underscore the need for continued research and policy action to reduce household air pollution exposures and protect maternal and fetal health.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"26"},"PeriodicalIF":2.8,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145793987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-18DOI: 10.1186/s41043-025-01205-6
Maysam R Homsi, Carol Underwood, Olakunle Alonge, Miguela A Caniza, Melissa A Davey-Rothwell
Background: It is estimated that approximately 80% of childhood cancer cases occur in resource-limited settings and that most unvaccinated children live in middle-income countries. This creates an overlap of burdens for children with cancer, who are especially vulnerable to vaccine-preventable infections such as influenza and invasive pneumococcal disease. Given the complexity of vaccinating children with cancer because of the multidisciplinary care they require, it is unclear how such vaccination is achieved in these settings.
Methods: A self-administered, anonymized, cross-sectional survey was distributed to providers of healthcare for children with cancer in Latin America and the Caribbean through a contact list of 3236 email addresses. A total of 378 participant responses were included in the final analysis. This study used the Consolidated Framework for Implementation Research to understand the implementation factors influencing the vaccination of children with cancer in Latin America and the Caribbean.
Results: Most respondents (n = 246, 65.3%) reported that vaccines were always, almost always, or often available for administration at their institution - and were willing to recommend children with cancer for vaccination. Most respondents reported receiving no training or education on immunizing children with cancer at their current institution (n = 297, 78.6%) or before joining it (n = 242, 64.0%). Furthermore, only a small minority reported working in institutions with written policies on vaccinating children with cancer (n = 53, 14.0%) or clinical guidelines (n = 97, 25.7%) for vaccinating these patients. Respondents estimated that most pediatric patients with cancer at their hospital were not up to date on childhood immunizations and did not receive the annual influenza vaccine. Although most respondents (n = 345, 91.3%) reported that their government provides funding for childhood vaccinations, fewer than half (n = 183, 48.5%) reported that government funding was available for re-immunizing children with cancer.
Conclusions: We found a clear willingness to recommend vaccines for children with cancer in Latin America and the Caribbean, a trend not found in similar studies in the literature. Our findings support the notion that interventions to improve vaccination for children with cancer should gear their efforts towards building an institutional culture that prioritizes immunization for both patients and staff and that supports providers in their already established practice of recommending vaccines to their patients.
{"title":"Implementation factors and healthcare provider willingness to vaccinate in Latin America and the Caribbean.","authors":"Maysam R Homsi, Carol Underwood, Olakunle Alonge, Miguela A Caniza, Melissa A Davey-Rothwell","doi":"10.1186/s41043-025-01205-6","DOIUrl":"10.1186/s41043-025-01205-6","url":null,"abstract":"<p><strong>Background: </strong>It is estimated that approximately 80% of childhood cancer cases occur in resource-limited settings and that most unvaccinated children live in middle-income countries. This creates an overlap of burdens for children with cancer, who are especially vulnerable to vaccine-preventable infections such as influenza and invasive pneumococcal disease. Given the complexity of vaccinating children with cancer because of the multidisciplinary care they require, it is unclear how such vaccination is achieved in these settings.</p><p><strong>Methods: </strong>A self-administered, anonymized, cross-sectional survey was distributed to providers of healthcare for children with cancer in Latin America and the Caribbean through a contact list of 3236 email addresses. A total of 378 participant responses were included in the final analysis. This study used the Consolidated Framework for Implementation Research to understand the implementation factors influencing the vaccination of children with cancer in Latin America and the Caribbean.</p><p><strong>Results: </strong>Most respondents (n = 246, 65.3%) reported that vaccines were always, almost always, or often available for administration at their institution - and were willing to recommend children with cancer for vaccination. Most respondents reported receiving no training or education on immunizing children with cancer at their current institution (n = 297, 78.6%) or before joining it (n = 242, 64.0%). Furthermore, only a small minority reported working in institutions with written policies on vaccinating children with cancer (n = 53, 14.0%) or clinical guidelines (n = 97, 25.7%) for vaccinating these patients. Respondents estimated that most pediatric patients with cancer at their hospital were not up to date on childhood immunizations and did not receive the annual influenza vaccine. Although most respondents (n = 345, 91.3%) reported that their government provides funding for childhood vaccinations, fewer than half (n = 183, 48.5%) reported that government funding was available for re-immunizing children with cancer.</p><p><strong>Conclusions: </strong>We found a clear willingness to recommend vaccines for children with cancer in Latin America and the Caribbean, a trend not found in similar studies in the literature. Our findings support the notion that interventions to improve vaccination for children with cancer should gear their efforts towards building an institutional culture that prioritizes immunization for both patients and staff and that supports providers in their already established practice of recommending vaccines to their patients.</p>","PeriodicalId":15969,"journal":{"name":"Journal of Health, Population, and Nutrition","volume":" ","pages":"25"},"PeriodicalIF":2.8,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145781174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}